SPRINT Home UMBER Home Contents Standard Search Advanced Search Relation Search

==SPRINT==> PRINTS View



  selected as


PR01705

Identifier
TSP1REPEAT  [View Relations]  [View Alignment]  
Accession
PR01705
No. of Motifs
3
Creation Date
31-MAR-2002
Title
Thrombospondin type 1 repeat signature
Database References

PROSITE; PS50092 TSP1
PFAM; PF00090 tsp_1
INTERPRO; IPR000884
Literature References
1. LAWLER, J. AND HYNES, R.O.
The structure of human thrombospondin, an adhesive glycoprotein with
multiple calcium-binding sites and homologies with several different
proteins.
J.CELL BIOL. 103(5) 1635-1648 (1986).
 
2. ADAMS, J.C. AND TUCKER, R.P.
The thrombospondin type 1 repeat (TSR) superfamily: diverse proteins with
related roles in neuronal development.
DEV.DYN. 218(2) 280-299 (2000). 
 
3. SMITH, K.F., NOLAN, K.F., REID, K.B. AND PERKINS, S.J.
Neutron and X-ray scattering studies on the human complement protein
properdin provide an analysis of the thrombospondin repeat.
BIOCHEMISTRY 30(32) 8000-8008 (1991).

Documentation
The TSP1 (thrombospondin 1) repeat was first identified in the
thrombospondin protein, where it is repeated 3 times [1]. The domain is 
~60 amino acid residues in length and is characterised by a highly 
conserved W-S-X-W motif and six cysteine residues [2]. TSP1 repeats have  
been identified in a number of proteins including: the complement pathway
proteins properdin, C6, C7, C8A, C8B and C9; extracellular matrix proteins,
including mindin, ADAMTS and F-spondin; Plasmodium TRAP proteins; and G 
protein-coupled receptors, such as the brain-specific angiogenesis 
inhibitors [2]. The domains have a number of functions, including effects 
on cell attachment, motility, proliferation, the activities of extracellular
proteases, and inhibition of angiogenesis, contributing to vascular 
homeostasis [2]. A study of the structure of properdin indicates that the 
TSP1 repeat contains two amphipathic turn regions and a hydrophilic 
beta-strand [3].
 
TSP1REPEAT is a 3-element fingerprint that provides a signature for the
thrombospondin type 1 repeat. The fingerprint was derived from an initial
alignment of 5 sequences: the motifs were drawn from conserved regions
spanning the full length of the domain - motif 1 encodes the well-conserved
N-terminal portion, including the W-S-X-W motif; and motifs 2 and 3 span the
less conserved central and C-terminal portions of the repeat, respectively.
Four iterations on SPTR40_18f were required to reach convergence, at which
point a true set comprising 87 sequences was identified. Numerous partial
matches were also found: all are thrombospondin repeat-containing proteins
that fail to match one of the motifs.
Summary Information
  87 codes involving  3 elements
36 codes involving 2 elements
Composite Feature Index
3878787
2352512
123
True Positives
ATS1_HUMAN    ATS1_MOUSE    ATS1_RAT      ATS2_BOVIN    
ATS2_HUMAN ATS4_HUMAN ATS5_HUMAN ATS5_MOUSE
ATS6_HUMAN ATS7_HUMAN ATS8_HUMAN ATS8_MOUSE
ATS9_HUMAN BAI1_HUMAN BAI2_HUMAN BAI3_HUMAN
CO6_HUMAN CO7_HUMAN CO8A_HUMAN CO8A_RABIT
CO8B_HUMAN CO8B_RABIT CO9_FUGRU FSPO_RAT
O00816 O08721 O08722 O08747
O17347 O42113 O42114 O43981
O44171 O76822 O95185 O95428
PROP_CAVPO PROP_HUMAN Q17591 Q18206
Q19092 Q19204 Q19284 Q19349
Q19522 Q19764 Q19791 Q22580
Q22631 Q93243 Q9CRC7 Q9D398
Q9EPX2 Q9ERI1 Q9GLX9 Q9GQR0
Q9HCB6 Q9NBL0 Q9NS62 Q9PTY3
Q9PVW7 Q9QXT7 Q9TUQ3 Q9TYK4
Q9U631 Q9U8J9 Q9UGQ1 Q9V7B4
Q9VAV4 Q9VF61 Q9VTT0 Q9W493
Q9W770 Q9XVU5 Q9XZM7 SM5A_HUMAN
SM5A_MOUSE SM5B_MOUSE TOH2_CAEEL TSP1_BOVIN
TSP1_HUMAN TSP1_MOUSE TSP1_XENLA TSP2_BOVIN
TSP2_CHICK TSP2_HUMAN TSP2_MOUSE
True Positive Partials
Codes involving 2 elements
FSPO_XENLA O44938 O61126 O62134
O62135 O75339 O76840 P90573
P90884 Q01502 Q01503 Q01504
Q01505 Q01506 Q01508 Q01509
Q01510 Q04588 Q19305 Q23729
Q26020 Q94662 Q9BLJ2 Q9CX59
Q9GTW7 Q9JM61 Q9PVW6 Q9U8G8
Q9V692 Q9V693 Q9VWA7 Q9W1Z6
Q9Y1V4 Q9Y1V5 SSP2_PLAYO TRAP_PLAFA
Sequence Titles
ATS1_HUMAN  ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1) - Homo sapiens (Human). 
ATS1_MOUSE ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) - Mus musculus (Mouse).
ATS1_RAT ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) - Rattus norvegicus (Rat).
ATS2_BOVIN ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino-propeptide processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI) - Bos taurus (Bovine).
ATS2_HUMAN ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino-propeptide processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI) (Procollagen I/II amino-propeptide processing enzyme) - Homo sapiens (Human).
ATS4_HUMAN ADAMTS-4 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase 1) (ADMP-1) - Homo sapiens (Human).
ATS5_HUMAN ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11) - Homo sapiens (Human).
ATS5_MOUSE ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin) - Mus musculus (Mouse).
ATS6_HUMAN ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6) - Homo sapiens (Human).
ATS7_HUMAN ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7) - Homo sapiens (Human).
ATS8_HUMAN ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH-8) - Homo sapiens (Human).
ATS8_MOUSE ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) - Mus musculus (Mouse).
ATS9_HUMAN ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9) - Homo sapiens (Human).
BAI1_HUMAN Brain-specific angiogenesis inhibitor 1 precursor - Homo sapiens (Human).
BAI2_HUMAN Brain-specific angiogenesis inhibitor 2 precursor - Homo sapiens (Human).
BAI3_HUMAN Brain-specific angiogenesis inhibitor 3 precursor - Homo sapiens (Human).
CO6_HUMAN Complement component C6 precursor - Homo sapiens (Human).
CO7_HUMAN Complement component C7 precursor - Homo sapiens (Human).
CO8A_HUMAN Complement component C8 alpha chain precursor - Homo sapiens (Human).
CO8A_RABIT Complement component C8 alpha chain precursor - Oryctolagus cuniculus (Rabbit).
CO8B_HUMAN Complement component C8 beta chain precursor - Homo sapiens (Human).
CO8B_RABIT Complement component C8 beta chain precursor - Oryctolagus cuniculus (Rabbit).
CO9_FUGRU Complement component C9 precursor - Fugu rubripes (Japanese pufferfish) (Takifugu rubripes).
FSPO_RAT F-spondin precursor - Rattus norvegicus (Rat).
O00816 MICRONEMAL PROTEIN MIC2 - Toxoplasma gondii.
O08721 TRANSMEMBRANE RECEPTOR UNC5H1 - Rattus norvegicus (Rat).
O08722 TRANSMEMBRANE RECEPTOR UNC5H2 - Rattus norvegicus (Rat).
O08747 UNC-5 HOMOLOG (C. ELEGANS) 3 (ROSTRAL CEREBELLAR MALFORMATION PROTEIN) - Mus musculus (Mouse).
O17347 H42K12.3 PROTEIN - Caenorhabditis elegans.
O42113 F-SPONDIN1 - Brachydanio rerio (Zebrafish) (Zebra danio).
O42114 F-SPONDIN2 - Brachydanio rerio (Zebrafish) (Zebra danio).
O43981 MICRONEME PROTEIN PRECURSOR ETMIC-1 - Eimeria tenella.
O44171 C. ELEGANS UNC-5 (NID:G25852) - Caenorhabditis elegans.
O76822 F-SPONDIN - Branchiostoma floridae (Florida lancelet) (Amphioxus).
O95185 TRANSMEMBRANE RECEPTOR UNC5C - Homo sapiens (Human).
O95428 Hypothetical protein - Homo sapiens (Human).
PROP_CAVPO Properdin precursor - Cavia porcellus (Guinea pig).
PROP_HUMAN Properdin precursor - Homo sapiens (Human).
Q17591 C02B4.1 PROTEIN - Caenorhabditis elegans.
Q18206 C26C6.3 PROTEIN - Caenorhabditis elegans.
Q19092 SIMILAR TO THROMBOSPONDIN - Caenorhabditis elegans.
Q19204 HYPOTHETICAL PROTEIN F08C6.1 - Caenorhabditis elegans.
Q19284 SIMILAR TO TYPE I THROMBOSPONDIN - Caenorhabditis elegans.
Q19349 COSMID F11C7 - Caenorhabditis elegans.
Q19522 F53B7.5 PROTEIN - Caenorhabditis elegans.
Q19764 F23H12.5 PROTEIN - Caenorhabditis elegans.
Q19791 F25H8.3 protein - Caenorhabditis elegans.
Q22580 SIMILARITY TO TYPE-1 TSP REPEATS - Caenorhabditis elegans.
Q22631 T21B6.3 PROTEIN - Caenorhabditis elegans.
Q93243 C17G1.6 PROTEIN - Caenorhabditis elegans.
Q9CRC7 2010109H09Rik protein - Mus musculus (Mouse).
Q9D398 6330415E02RIK PROTEIN - Mus musculus (Mouse).
Q9EPX2 Papilin - Mus musculus (Mouse).
Q9ERI1 ADAMTS-1 - Rattus norvegicus (Rat).
Q9GLX9 VSGP/F-SPONDIN - Bos taurus (Bovine).
Q9GQR0 Extracellular matrix protein papilin precursor - Drosophila melanogaster (Fruit fly).
Q9HCB6 VSGP/F-SPONDIN - Homo sapiens (Human).
Q9NBL0 NETRIN RECEPTOR DUNC5 - Drosophila melanogaster (Fruit fly).
Q9NS62 TRANSMEMBRANE MOLECULE WITH THROMBOSPONDIN MODULE PRECURSOR - Homo sapiens (Human).
Q9PTY3 COMPLEMENT COMPONENT C7 - Paralichthys olivaceus (Flounder).
Q9PVW7 COMPLEMENT COMPONENT C8 BETA - Paralichthys olivaceus (Flounder).
Q9QXT7 COMPLEMENT COMPONENT 6 - Mus musculus (Mouse).
Q9TUQ3 COMPLEMENT COMPONENT C7 PRECURSOR - Sus scrofa (Pig).
Q9TYK4 Y8A9A.2 PROTEIN - Caenorhabditis elegans.
Q9U631 SEMAPHORIN 5C PROTEIN - Drosophila melanogaster (Fruit fly).
Q9U8J9 THROMBOSPONDIN-RELATED ADHESIVE PROTEIN HOMOLOG - Neospora caninum.
Q9UGQ1 Hypothetical protein - Homo sapiens (Human).
Q9V7B4 CG8166 PROTEIN - Drosophila melanogaster (Fruit fly).
Q9VAV4 CG1540 protein - Drosophila melanogaster (Fruit fly).
Q9VF61 CG6107 PROTEIN - Drosophila melanogaster (Fruit fly).
Q9VTT0 SEMA-5C PROTEIN - Drosophila melanogaster (Fruit fly).
Q9W493 CG4096 protein - Drosophila melanogaster (Fruit fly).
Q9W770 F-SPONDIN PRECURSOR - Gallus gallus (Chicken).
Q9XVU5 F15B9.8 PROTEIN - Caenorhabditis elegans.
Q9XZM7 CORTICAL GRANULE SERINE PROTEASE 1 PRECURSOR - Strongylocentrotus purpuratus (Purple sea urchin).
SM5A_HUMAN Semaphorin 5A precursor (Semaphorin F) (Sema F) - Homo sapiens (Human).
SM5A_MOUSE Semaphorin 5A precursor (Semaphorin F) (Sema F) - Mus musculus (Mouse).
SM5B_MOUSE Semaphorin 5B precursor (Semaphorin G) (Sema G) - Mus musculus (Mouse).
TOH2_CAEEL Zinc metalloproteinase toh-2 precursor (EC 3.4.24.-) - Caenorhabditis elegans.
TSP1_BOVIN Thrombospondin 1 precursor - Bos taurus (Bovine).
TSP1_HUMAN Thrombospondin 1 precursor - Homo sapiens (Human).
TSP1_MOUSE Thrombospondin 1 precursor - Mus musculus (Mouse).
TSP1_XENLA Thrombospondin 1 precursor - Xenopus laevis (African clawed frog).
TSP2_BOVIN Thrombospondin 2 precursor (Corticotropin-induced secreted protein) (CISP) - Bos taurus (Bovine).
TSP2_CHICK Thrombospondin 2 precursor - Gallus gallus (Chicken).
TSP2_HUMAN Thrombospondin 2 precursor - Homo sapiens (Human).
TSP2_MOUSE Thrombospondin 2 precursor - Mus musculus (Mouse).

FSPO_XENLA F-spondin precursor - Xenopus laevis (African clawed frog).
O44938 Thrombospondin - Haemonchus contortus (Barber pole worm).
O61126 SPOROZOITE CYSTEINE-RICH PROTEIN - Cryptosporidium parvum.
O62134 F02H6.6 PROTEIN - Caenorhabditis elegans.
O62135 F02H6.7 PROTEIN - Caenorhabditis elegans.
O75339 CARTILAGE INTERMEDIATE LAYER PROTEIN - Homo sapiens (Human).
O76840 Hypothetical protein C37C3.6b - Caenorhabditis elegans.
P90573 PBTRAP - Plasmodium berghei (strain Anka).
P90884 Hypothetical protein F53B6.2a - Caenorhabditis elegans.
Q01502 THROMBOSPONDIN RELATED ANONYMOUS PROTEIN - Plasmodium falciparum.
Q01503 THROMBOSPONDIN RELATED ANONYMOUS PROTEIN - Plasmodium falciparum.
Q01504 THROMBOSPONDIN RELATED ANONYMOUS PROTEIN - Plasmodium falciparum.
Q01505 THROMBOSPONDIN RELATED ANONYMOUS PROTEIN - Plasmodium falciparum.
Q01506 THROMBOSPONDIN RELATED ANONYMOUS PROTEIN - Plasmodium falciparum.
Q01508 THROMBOSPONDIN RELATED ANONYMOUS PROTEIN - Plasmodium falciparum.
Q01509 THROMBOSPONDIN RELATED ANONYMOUS PROTEIN - Plasmodium falciparum.
Q01510 THROMBOSPONDIN RELATED ANONYMOUS PROTEIN - Plasmodium falciparum.
Q04588 MICRONEME PROTEIN ETP100 - Eimeria maxima.
Q19305 SIMILAR TO F-SPONDIN. NCBI GI: 1086836 - Caenorhabditis elegans.
Q23729 THROMBOSPONDIN RELATED ADHESIVE PROTEIN (TRAP-C1) - Cryptosporidium parvum.
Q26020 SPOROZOITE SURFACE PROTEIN 2 - Plasmodium falciparum.
Q94662 THROMBOSPONDIN RELATED ADHESIVE PROTEIN - Plasmodium falciparum.
Q9BLJ2 CI-META2 - Ciona intestinalis.
Q9CX59 6720426B09Rik protein - Mus musculus (Mouse).
Q9GTW7 SPOROZOITE SURFACE PROTEIN 2 - Plasmodium falciparum.
Q9JM61 TRANSMEMBRANE MOLECULE WITH THROMBOSPONDIN MODULE PRECURSOR - Mus musculus (Mouse).
Q9PVW6 COMPLEMENT COMPONENT C9 - Paralichthys olivaceus (Flounder).
Q9U8G8 Lacunin precursor - Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm).
Q9V692 CG17739 PROTEIN - Drosophila melanogaster (Fruit fly).
Q9V693 CG17740 PROTEIN - Drosophila melanogaster (Fruit fly).
Q9VWA7 CG13817 PROTEIN - Drosophila melanogaster (Fruit fly).
Q9W1Z6 CG3622 PROTEIN - Drosophila melanogaster (Fruit fly).
Q9Y1V4 HREPIC PROTEIN - Halocynthia roretzi (Sea squirt).
Q9Y1V5 HREPIC PROTEIN - Halocynthia roretzi (Sea squirt).
SSP2_PLAYO Sporozoite surface protein 2 precursor - Plasmodium berghei yoelii.
TRAP_PLAFA Thrombospondin related anonymous protein precursor - Plasmodium falciparum.
Scan History
SPTR40_18f 4  500  NSINGLE    
Initial Motifs
Motif 1  width=14
Element Seqn Id St Int Rpt
GNWNEWSSWSACSA BAI1_HUMAN 468 468 R4
GGWSGWGPWEPCSV PROP_HUMAN 137 137 -
GHWSCWGSWSPCTA CO8A_RABIT 541 541 -
GGWSCWSSWSPCVQ CO7_HUMAN 501 501 -
GRWSPWSPWSACTV TSP2_BOVIN 493 493 R2
GGWSHWSPWSSCSV TSP1_HUMAN 436 436 -
GGWSHWSPWSSCSV TSP2_MOUSE 438 438 -
GQWGCWSSWSTCDA CO6_HUMAN 566 566 -
GKWNCWSNWSSCSG CO8B_HUMAN 546 546 -
GGWSHWSPWSSCSV TSP1_XENLA 439 439 R1

Motif 2 width=12
Element Seqn Id St Int Rpt
GRQQRTRECNGP BAI1_HUMAN 486 4 R4
GTRTRRRACNHP PROP_HUMAN 155 4 -
GTRERRRECNNP CO8A_RABIT 555 0 -
GKKTRSRECNNP CO7_HUMAN 515 0 -
GIRERTRVCNSP TSP2_BOVIN 511 4 R2
GVITRIRLCNSP TSP1_HUMAN 454 4 -
GNVTRIRLCNSP TSP2_MOUSE 456 4 -
YKRSRTRECNNP CO6_HUMAN 581 1 -
RRKTRQRQCNNP CO8B_HUMAN 560 0 -
GQITRIRLCNSP TSP1_XENLA 457 4 R1

Motif 3 width=12
Element Seqn Id St Int Rpt
ECQGHWVETRDC BAI1_HUMAN 503 5 R4
HCPGQAQESEAC PROP_HUMAN 173 6 -
PCPGWRVQTQAC CO8A_RABIT 574 7 -
SCVGETTESTQC CO7_HUMAN 534 7 -
DCVGGAKEQQMC TSP2_BOVIN 530 7 R2
PCEGEARETKAC TSP1_HUMAN 473 7 -
NCKGSGRETKPC TSP2_MOUSE 475 7 -
RCEGEKRQEEDC CO6_HUMAN 600 7 -
PCSGPASETLDC CO8B_HUMAN 579 7 -
QCEGEGRENKPC TSP1_XENLA 476 7 R1
Final Motifs
Motif 1  width=14
Element Seqn Id St Int Rpt
GGWSAWSEWSACSE Q19284 317 317 -
GNWNEWSSWSACSA BAI1_HUMAN 468 468 R4
GRWSCWSRWSSCSG CO8B_RABIT 546 546 -
GGWSSWAEWSPCSN Q9D398 247 247 -
GGWSGWGPWEPCSV PROP_HUMAN 137 137 -
GGWSSWAEWSPCSN O08722 247 247 -
GGWSCWSSWGSCSG Q9PTY3 486 486 -
GHWSCWGSWSPCTA CO8A_RABIT 541 541 -
GGWSTWSKWSKCRE Q19092 56 56 -
GGWSCWSSWSPCVQ CO7_HUMAN 501 501 -
GGWSTWTEWSVCSA O08721 243 243 -
GQWQEWSSWSQCSV BAI3_HUMAN 401 401 R3
GGWSTWSDWTPCSA Q17591 1308 1308 R2
GSWSCWSSWSVCRA CO8A_HUMAN 540 540 -
GGWATWGPWSSCSR SM5B_MOUSE 796 796 R2
GAWSAWTSWSQCSR SM5A_HUMAN 785 785 R2
GEWGCWSEWSACSV Q9U631 839 839 R1
GEWGCWSEWSACSV Q9VTT0 841 841 R1
AEWTEWCEWSGCSS Q22631 652 652 R2
SGVEEWSQWSTCSV BAI3_HUMAN 292 292 R1
GGWTPWTSWSPCST SM5A_HUMAN 596 596 R1
GGWTPWTSWSPCST SM5A_MOUSE 596 596 R1
GRWSPWSPWSACTV TSP2_BOVIN 493 493 R2
GGWSNWEPWGPCTV PROP_CAVPO 136 136 -
GAWSAWTSWSQCSR SM5A_MOUSE 785 785 R2
GSWGPWGPWGDCSR ATS1_MOUSE 561 561 -
GSWGPWGPWGDCSR ATS1_RAT 560 560 -
GGWSCWSSWGPCAQ Q9TUQ3 501 501 -
GAWDEWSPWSLCSS BAI1_HUMAN 410 410 R3
GVWEEWGSWSLCSR BAI2_HUMAN 353 353 R2
GGWSTWTEWSVCNS O08747 261 261 -
GGWSTWTEWSVCNS O95185 261 261 -
GSWGMWGPWGDCSR ATS1_HUMAN 560 560 -
GGWSHWSPWSSCSV TSP1_HUMAN 436 436 -
GGWSHWSPWSSCSV TSP1_MOUSE 436 436 -
GSWGPWGPWGDCSR Q9ERI1 544 544 -
YGWSSWGDWSECHP Q9XZM7 259 259 -
GGWSGWSAWSICSR ATS7_HUMAN 539 539 -
GVWEEWSPWSLCSF BAI3_HUMAN 346 346 R2
GLWNDWGAWTTCSA Q9TYK4 1203 1203 R2
PAAEEWSPWSVCSL BAI2_HUMAN 298 298 R1
GGWSHWSPWSSCSV TSP1_BOVIN 436 436 -
GRWSPWSPWSACTV TSP2_HUMAN 495 495 R2
LGWSAWSEWSSCSS Q9U631 892 892 R2
LGWSAWSEWSSCSS Q9VTT0 894 894 R2
GNWNSWSPWTACSA TOH2_CAEEL 491 491 -
GKWQAWASWGSCSV BAI1_HUMAN 523 523 R5
GGWGPWSLWGECSR ATS6_HUMAN 511 511 -
GGWGDWSEWSECSR Q9W493 624 624 -
GVWGTWGGWSTCST Q19204 856 856 -
ESWSEWSDWSECEA SM5A_HUMAN 897 897 R3
GGWKLWSLWGECTR BAI1_HUMAN 262 262 R1
PAAEEWSPWSVCSS BAI1_HUMAN 355 355 R2
GGWSLWSEWSSCSK Q17591 1187 1187 R1
ESWSEWSDWSVCDA SM5A_MOUSE 897 897 R3
GGWSHWSPWSSCSV TSP2_BOVIN 436 436 R1
GQWLEWGPWGPCST BAI2_HUMAN 408 408 R3
GGWGPWGPWGDCSR ATS4_HUMAN 521 521 -
GNWGSWGPWGQCSR ATS5_MOUSE 568 568 -
GGWSHWSPWSSCSV TSP2_MOUSE 438 438 -
GEWTPWGSWSRCSS Q9CRC7 47 47 -
GNWGSWGSWGQCSR ATS5_HUMAN 568 568 -
GQWGCWSSWSTCDA CO6_HUMAN 566 566 -
GRWSSWGPRSPCSR Q9UGQ1 57 57 -
GKWNCWSNWSSCSG CO8B_HUMAN 546 546 -
GDWGPWRPWGQCSR ATS8_MOUSE 543 543 -
GAWTAWSSWAQCST SM5B_MOUSE 607 607 R1
DTWGPWSQWSPCSR O95428 27 27 -
PEWSQWEDWGQCSV Q22631 552 552 R1
NVWADWGEWSMCSR Q18206 542 542 -
GEWSAWNEWSGCMG Q17591 1366 1366 R3
GSWGAWSPFGSCSR ATS2_HUMAN 562 562 -
GGWSHWSPWSSCSV TSP2_CHICK 444 444 -
GNWGCWSSWSACNA Q9QXT7 566 566 -
GSWSCWGAWSSCSG Q9PVW7 543 543 -
STWNAWQEWSTCTE Q19522 2684 2684 -
GQWGDWRSWGECSR Q19791 604 604 -
GGWSSWSDWSACSS O44171 303 303 -
GGWSHWSPWSSCSV TSP2_HUMAN 438 438 R1
GNWGAWSPFGSCSR ATS2_BOVIN 556 556 -
AVCSEWSEWSPCSA Q9U8J9 269 269 -
SSWSMWSPWSFCSN Q19764 29 29 -
GGWGPWTPFTPCSL Q9VF61 640 640 -
GGWAPWGPWGECSR ATS8_HUMAN 528 528 -
ETWGLWQPWSQCSA Q9NS62 341 341 -
EGWSLWSEWGVCTE SM5B_MOUSE 908 908 R3
DTWGTWGEWSPCSR Q9EPX2 28 28 -
GEWTEWTSWSMCQN Q9XVU5 98 98 -
GGWSHWSPWSSCSV TSP1_XENLA 439 439 R1
ASWSAWGEWSACSQ Q93243 577 577 -
NEWSGWSVWSECVT Q22580 637 637 -
GGWSTWSPWRECKC Q9NBL0 325 325 -
GGWSTWSPWRECKC Q9V7B4 325 325 -
GQWNQWGHWSGCSK BAI3_HUMAN 456 456 R4
SKWGPWNAWSLCSK BAI2_HUMAN 464 464 R4
AEWGEWEEWAACDN Q19349 70 70 -
AICSDWSAWSPCSV O00816 271 271 -
CTMSEWITWSPCSI Q9GLX9 502 502 -
CMMSEWISWSPCSA O42114 498 498 -
CLYSPWSEWSDCSV O76822 571 571 -
CMMSEWITWSPCSV O42113 502 502 -
GNWSCWSSWSNCQG CO9_FUGRU 544 544 -
GQWGPWSLWDTCTV TSP1_XENLA 496 496 R2
GSWGSWSPFGTCSR ATS9_HUMAN 589 589 -
CTMSEWITWSPCSV FSPO_RAT 502 502 -
CMMSDWITWSPCSV Q9W770 497 497 -
DEWTPWSSPSDCSR Q9GQR0 58 58 -
DEWTPWSSPSDCSR Q9VAV4 18 18 -
CTMSEWITWSPCSI Q9HCB6 502 502 -
AVCSEWSEYGPCVG O43981 240 240 -
GIWGEWVSVSGCND Q9TYK4 1105 1105 R1
TYFSDWSDWTPCTK O17347 382 382 -

Motif 2 width=12
Element Seqn Id St Int Rpt
GRQRRVRFCNEP Q19284 335 4 -
GRQQRTRECNGP BAI1_HUMAN 486 4 R4
GQKTRRRQCNNP CO8B_RABIT 560 0 -
GWQKRTRTCTNP Q9D398 265 4 -
GTRTRRRACNHP PROP_HUMAN 155 4 -
GWQKRTRTCTNP O08722 265 4 -
GRMSRTRSCNNP Q9PTY3 500 0 -
GTRERRRECNNP CO8A_RABIT 555 0 -
GIRKRRRTCNNP Q19092 70 0 -
GKKTRSRECNNP CO7_HUMAN 515 0 -
GWQKRSRSCTNP O08721 261 4 -
GTQQRSRQCTAA BAI3_HUMAN 419 4 R3
GVQTRDRSCSSP Q17591 1326 4 R2
GIQERRRECDNP CO8A_HUMAN 554 0 -
GFRVRKRTCTNP SM5B_MOUSE 814 4 R2
GIRNRKRVCNNP SM5A_HUMAN 803 4 R2
GLRRRTRRCLAG Q9U631 857 4 R1
GLRRRTRRCLAG Q9VTT0 859 4 R1
GQRTRTRGCLGP Q22631 670 4 R2
GSQVRTRTCVSP BAI3_HUMAN 310 4 R1
GFQVRQRSCSNP SM5A_HUMAN 614 4 R1
GFQVRQRSCSNP SM5A_MOUSE 614 4 R1
GIRERTRVCNSP TSP2_BOVIN 511 4 R2
GTRIRRRVCNNP PROP_CAVPO 154 4 -
GIRNRKRVCNNP SM5A_MOUSE 803 4 R2
GVQYTMRECDNP ATS1_MOUSE 579 4 -
GVQYTMRECDNP ATS1_RAT 578 4 -
GKKTRSRKCNNP Q9TUQ3 515 0 -
GFRDRTRTCRPP BAI1_HUMAN 428 4 R3
GSRSRMRTCVPP BAI2_HUMAN 371 4 R2
GYQKRTRTCTNP O08747 279 4 -
GYQKRTRTCTNP O95185 279 4 -
GVQYTMRECDNP ATS1_HUMAN 578 4 -
GVITRIRLCNSP TSP1_HUMAN 454 4 -
GVITRIRLCNSP TSP1_MOUSE 454 4 -
GVQYTMRECDNP Q9ERI1 562 4 -
GTRSRSRFCASP Q9XZM7 277 4 -
GVQSAERQCTQP ATS7_HUMAN 557 4 -
GQRTRTRSCTPP BAI3_HUMAN 364 4 R2
GTQTRSRTCASA Q9TYK4 1222 5 R2
GLQVRTRSCVSS BAI2_HUMAN 316 4 R1
GVITRIRLCNSP TSP1_BOVIN 454 4 -
GIRERTRVCNSP TSP2_HUMAN 513 4 R2
GIRLRHRRCLVE Q9U631 907 1 R2
GIRLRHRRCLVE Q9VTT0 909 1 R2
GSRMRTRTCPPG TOH2_CAEEL 510 5 -
GSQRRERVCSGP BAI1_HUMAN 541 4 R5
GVSSSLRHCDSP ATS6_HUMAN 529 4 -
GVSTQQRECDNP Q9W493 642 4 -
GTLVRQRTCNRE Q19204 874 4 -
GVQVRARQCILL SM5A_HUMAN 912 1 R3
GLQTRTRTCLPA BAI1_HUMAN 280 4 R1
GWQTRTRFCVSS BAI1_HUMAN 373 4 R2
GHQIRNRMCSEP Q17591 1206 5 R1
GTQVRARQCILL SM5A_MOUSE 912 1 R3
GNVTRIRLCNSP TSP2_BOVIN 454 4 R1
GTQQRSRKCSVA BAI2_HUMAN 426 4 R3
GVQFSSRDCTRP ATS4_HUMAN 539 4 -
GVQFAYRHCNNP ATS5_MOUSE 586 4 -
GNVTRIRLCNSP TSP2_MOUSE 456 4 -
GVSVRRRQCVRL Q9CRC7 65 4 -
GVQFAYRHCNNP ATS5_HUMAN 586 4 -
YKRSRTRECNNP CO6_HUMAN 581 1 -
GVVTRRRQCNNP Q9UGQ1 75 4 -
RRKTRQRQCNNP CO8B_HUMAN 560 0 -
GIQFSNRECDNP ATS8_MOUSE 561 4 -
GFQVRQRSCSNP SM5B_MOUSE 625 4 R1
GVSFRERPCYSQ O95428 45 4 -
GVAVRQRTCLGG Q22631 570 4 R1
GIRSRVRSCRSK Q18206 561 5 -
GTRTRVRACVSP Q17591 1384 4 R3
GVKFRTRQCDNP ATS2_HUMAN 580 4 -
GNITRIRLCNSP TSP2_CHICK 462 4 -
YRRSRTRECNNP Q9QXT7 581 1 -
RKMSRSRQCNNP Q9PVW7 557 0 -
GTQQRFRSCNKP Q19522 2703 5 -
GVQKGLRDCDSP Q19791 622 4 -
CHRYRTRACTVP O44171 318 1 -
GNITRIRLCNSP TSP2_HUMAN 456 4 R1
GVKFRTRQCDNP ATS2_BOVIN 574 4 -
GTQGRTRQQLSP Q9U8J9 287 4 -
GKQSRKRKCLKY Q19764 718 675 -
GVQESRRECNQP Q9VF61 658 4 -
GVQFSHRECKDP ATS8_HUMAN 546 4 -
GVRERRRVCLTS Q9NS62 359 4 -
GAQSRSRSCEEL SM5B_MOUSE 923 1 R3
GISFRERPCYSQ Q9EPX2 46 4 -
GERSRVRTCVSR Q9XVU5 112 0 -
GQITRIRLCNSP TSP1_XENLA 457 4 R1
GTKTRVRACYGG Q93243 596 5 -
GVKVRVRRCLAG Q22580 657 6 -
QGRKRSRTCNNP Q9NBL0 344 5 -
QGRKRSRTCNNP Q9V7B4 344 5 -
GWERRIRTCQGA BAI3_HUMAN 474 4 R4
GWQRRFRMCQAT BAI2_HUMAN 482 4 R4
GTHARTRTCELL Q19349 89 5 -
GSQIRTRTEVSA O00816 289 4 -
GTRSRERYVKQF Q9GLX9 520 4 -
GMRSRERYVKQF O42114 516 4 -
GVRKRNRVLKSL O76822 589 4 -
GLRSRERYVKQF O42113 520 4 -
QKRSRTRYCNTE CO9_FUGRU 558 0 -
GMQKRERLCNNP TSP1_XENLA 514 4 R2
GIKTAIRECNRP ATS9_HUMAN 607 4 -
GMRSRERYVKQF FSPO_RAT 520 4 -
GTRSRERYVKQF Q9W770 515 4 -
GVSYQTRECLRR Q9GQR0 76 4 -
GVSYQTRECLRR Q9VAV4 36 4 -
GMRSRERYVKQF Q9HCB6 520 4 -
GVQTSTRVEISP O43981 259 5 -
GQETRKRKCLSL Q9TYK4 1124 5 R1
ERQVRRRRCLNL O17347 398 2 -

Motif 3 width=12
Element Seqn Id St Int Rpt
YCDGPLIETQEC Q19284 353 6 -
ECQGHWVETRDC BAI1_HUMAN 503 5 R4
PCSGPASETLAC CO8B_RABIT 579 7 -
FCEGQAFQKTAC Q9D398 284 7 -
HCPGQAQESEAC PROP_HUMAN 173 6 -
FCEGQACQKTAC O08722 284 7 -
HCTGLRAEQKPC Q9PTY3 519 7 -
PCPGWRVQTQAC CO8A_RABIT 574 7 -
TCSGQKVEKQSC Q19092 87 5 -
SCVGETTESTQC CO7_HUMAN 534 7 -
FCEGQNVQKTAC O08721 280 7 -
ECRGPWAESREC BAI3_HUMAN 436 5 R3
SCSGLAHQTSLC Q17591 1344 6 R2
SCPGRKVQTQAC CO8A_HUMAN 573 7 -
PCVGDAAEYQDC SM5B_MOUSE 833 7 R2
PCLGPSLEYQEC SM5A_HUMAN 822 7 R2
LCQGRALEEQKC Q9U631 872 3 R1
LCQGRALEEQKC Q9VTT0 874 3 R1
TCQGPSIETTLC Q22631 688 6 R2
HCSGPLRESRVC BAI3_HUMAN 325 3 R1
VCVGQNREERYC SM5A_HUMAN 633 7 R1
VCVGQNREERYC SM5A_MOUSE 633 7 R1
DCVGGAKEQQMC TSP2_BOVIN 530 7 R2
HCPGVAQESEAC PROP_CAVPO 172 6 -
PCLGPSLEFQEC SM5A_MOUSE 822 7 R2
YCEGKRVRYRSC ATS1_MOUSE 598 7 -
YCEGKRVRYRSC ATS1_RAT 597 7 -
SCIGETSESRQC Q9TUQ3 534 7 -
PCEGPEKQTKFC BAI1_HUMAN 445 5 R3
ACEGPELQTKLC BAI2_HUMAN 388 5 R2
FCEGQSVQKIAC O08747 298 7 -
FCEGQSVQKIAC O95185 298 7 -
YCEGKRVRYRSC ATS1_HUMAN 597 7 -
PCEGEARETKAC TSP1_HUMAN 473 7 -
PCEGEARETKAC TSP1_MOUSE 473 7 -
YCEGKRVRYRFC Q9ERI1 581 7 -
RCLGESQEEEEC Q9XZM7 291 2 -
YCVGERKRFRLC ATS7_HUMAN 576 7 -
PCEGPETHHKPC BAI3_HUMAN 381 5 R2
PCTGDLTETQSC Q9TYK4 1238 4 R2
LCSGPLRETRPC BAI2_HUMAN 332 4 R1
PCEGKARETKAC TSP1_BOVIN 473 7 -
ACVGDVQERQMC TSP2_HUMAN 532 7 R2
ECRGAEFEKTAC Q9U631 924 5 R2
ECRGAEFEKTAC Q9VTT0 926 5 R2
ACSGEPVETQIC TOH2_CAEEL 523 1 -
ACQGPQDEYRQC BAI1_HUMAN 558 5 R5
YCLGERKRYRSC ATS6_HUMAN 548 7 -
FCIGERKRYKIC Q9W493 661 7 -
PCDGSAHERRSC Q19204 886 0 -
QCSGNTTESRPC SM5A_HUMAN 929 5 R3
GCEGVLEEGRQC BAI1_HUMAN 298 6 R1
QCSGPLREQRLC BAI1_HUMAN 389 4 R2
YCSGYSFDQRPC Q17591 1225 7 R1
QCSGNTTESRPC SM5A_MOUSE 929 5 R3
SCKGSGRETKAC TSP2_BOVIN 473 7 R1
TCTGALTDTREC BAI2_HUMAN 443 5 R3
YCEGRRTRFRSC ATS4_HUMAN 558 7 -
YCTGKRAIYRSC ATS5_MOUSE 605 7 -
NCKGSGRETKPC TSP2_MOUSE 475 7 -
LCWGDSHEYRVC Q9CRC7 81 4 -
YCTGKRAIYRSC ATS5_HUMAN 605 7 -
RCEGEKRQEEDC CO6_HUMAN 600 7 -
ACVGADLQAEMC Q9UGQ1 94 7 -
PCSGPASETLDC CO8B_HUMAN 579 7 -
FCLGERVKYQSC ATS8_MOUSE 580 7 -
ICVGKSREERFC SM5B_MOUSE 644 7 R1
SCVGPARSHRSC O95428 63 6 -
LCQGPKTEQRAC Q22631 587 5 R1
KCEGRRQEFGTC Q18206 573 0 -
PCFGRSSEITEC Q17591 1403 7 R3
TCSGLAYDFQLC ATS2_HUMAN 599 7 -
NCVGNGRETEKC TSP2_CHICK 481 7 -
SCGGKDQQEEDC Q9QXT7 600 7 -
ACRGLQQESTDC Q9PVW7 576 7 -
TCSGSAFEKEYC Q19522 2719 4 -
YCVGQRERYRSC Q19791 641 7 -
PCFGDDLMTQEC O44171 337 7 -
NCKGSGRETKAC TSP2_HUMAN 475 7 R1
TCSGLAYDFQLC ATS2_BOVIN 593 7 -
PCDFPTFQTQSC Q9U8J9 632 333 -
KCPSPQIEVQSC Q19764 786 56 -
YCTGSRKKYRSC Q9VF61 677 7 -
YCLGRRAKYQSC ATS8_HUMAN 565 7 -
VCPGMSLEASLC Q9NS62 376 5 -
ACVGNSSQSRPC SM5B_MOUSE 940 5 R3
SCVGPARSHRTC Q9EPX2 64 6 -
VCHGDAIEIEKC Q9XVU5 130 6 -
QCEGEGRENKPC TSP1_XENLA 476 7 R1
VCPGSNLDRESC Q93243 610 2 -
VCAGALRERQPC Q22580 669 0 -
LCAGKDIQTAEC Q9NBL0 482 126 -
LCAGKDIQTAEC Q9V7B4 482 126 -
QCEGTGEEVRRC BAI3_HUMAN 491 5 R4
PCEGTGEEVKPC BAI2_HUMAN 499 5 R4
LCTGDDNESEPC Q19349 107 6 -
PCDLPTFETKAC O00816 631 330 -
VCTLPTEETEKC Q9GLX9 537 5 -
SCTLPTEETEKC O42114 533 5 -
MCTDELEQTEQC O76822 604 3 -
ACTHPTEETEPC O42113 537 5 -
ECRGEIRSEEYC CO9_FUGRU 575 5 -
DCIGEPTDSQIC TSP1_XENLA 533 7 R2
YCVGRRMKFKSC ATS9_HUMAN 626 7 -
VCMLPTEETEKC FSPO_RAT 537 5 -
MCKVPTEETEKC Q9W770 532 5 -
VCSGGSRRYFSC Q9GQR0 94 6 -
VCSGGSRRYFSC Q9VAV4 54 6 -
VCTLPTEEMEKC Q9HCB6 537 5 -
MCSGDTHEVQSC O43981 594 323 -
ACTGNATDTSVC Q9TYK4 1140 4 R1
KCLGALMQVQNC O17347 411 1 -