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PR00795

Identifier
RYANODINER  [View Relations]  [View Alignment]  
Accession
PR00795
No. of Motifs
9
Creation Date
23-AUG-1997  (UPDATE 07-JUN-1999)
Title
Ryanodine receptor signature
Database References

INTERPRO; IPR001215
Literature References
1. WITCHER, D.R., KOVACS, R.J., SCHULMAN, H., CEFALI, D.C. AND JONES, L.R.
Unique phosphorylation site on the cardiac ryanodine receptor regulates
calcium channel activity.
J.BIOL.CHEM. 266 11144-11152 (1991).
 
2.QUANE, K.A., KEATING, K.E., HEALY, J.M., MANNING, B.M.,
KRIVOSIC-HORBER, R., KRIVOSIC, I., MONNIER, N., LUNARDI, J.
AND MCCARTHY, T.V.
Mutation screening of the RYR1 gene in malignant hyperthermia: detection
of a novel Tyr to Ser mutation in a pedigree with associated central cores.
GENOMICS 23(1) 236-239 (1994).
 
3. ZORZATO, F., FUJII, J., OTSU, K., PHILLIPS, M., GREEN, N.M., LAI, F.A.,
MEISSNER, G. AND MACLENNAN, D.H.
Molecular cloning of cdna encoding human and rabbit forms of the Ca2+
release channel (ryanodine receptor) of skeletal muscle sarcoplasmic
reticulum.
J.BIOL.CHEM. 265(4) 2244-2256 (1990).

Documentation
Ryanodine receptors are involved in communication between transverse-tubules
and the sarcoplamic reticulum of cardiac and skeletal muscle. The proteins 
function as a Ca2+-release channels following depolarisation of transverse-
tubules [1]. The function is modulated by Ca2+, Mg2+, ATP and calmodulin.
 
Deficiency in the ryanodine receptor may be the cause of malignant
hyperthermia (MH) and of central core disease of muscle (CCD) [2]. MH is
an autosomal dominant disorder of skeletal muscle and is a principal
cause of death due to anaesthesia.
 
Calcium release activity of the receptors resides in the C-terminal region
of the protein, the remaining part of the molecule forming a `foot'
structure that spans the junctional gap between the sarcoplamic reticulum
and the transverse-tubule. The foot structure may interact with the
cytoplasmic region of the dihydropyridine receptor.
 
Analysis of the sequence reveals 10 potential transmembrane (TM) regions
in the C-terminal fifth of the molecule and 2 further potential TM regions
nearer to the centre [3]. These may contribute to the formation of the Ca2+ 
conducting pore. The rest of the sequence is hydrophilic, and presumably
constitutes the cytoplasmic domain of the protein. 
 
RYANODINER is a 9-element fingerprint that provides a signature for the
ryanodine receptors. The fingerprint was derived from an initial alignment
of 9 sequences: the motifs were drawn from conserved regions spanning the
N-terminal third of the alignment, i.e. within the cytoplasmic domain. Two
iterations on OWL29.4 were required to reach convergence, at which point a
true set comprising 22 sequences was identified. A single partial match was
also found, CELK11C44, a C.elegans sequence that lacks the portion of
sequence bearing the first two motifs.
 
An update on SPTR37_9f identified a true set of 18 sequences, and 1
partial match.
Summary Information
  18 codes involving  9 elements
0 codes involving 8 elements
1 codes involving 7 elements
0 codes involving 6 elements
0 codes involving 5 elements
0 codes involving 4 elements
0 codes involving 3 elements
0 codes involving 2 elements
Composite Feature Index
9181818181818181818
8000000000
7001111111
6000000000
5000000000
4000000000
3000000000
2000000000
123456789
True Positives
O13054        P91905        Q24498        Q24499        
Q24500 Q24501 Q29104 Q29105
Q29621 Q90985 Q91313 Q91319
Q92736 Q95201 RYNC_RABIT RYNR_HUMAN
RYNR_PIG RYNR_RABIT
True Positive Partials
Codes involving 7 elements
Q94279
Sequence Titles
O13054      RYANODINE RECEPTOR RYR1 ISOFORM - MAKAIRA NIGRICANS. 
P91905 RYANODINE RECEPTOR - CAENORHABDITIS ELEGANS.
Q24498 RYANODINE RECEPTOR HOMOLOGUE - DROSOPHILA MELANOGASTER (FRUIT FLY).
Q24499 RYANODINE RECEPTOR HOMOLOGUE - DROSOPHILA MELANOGASTER (FRUIT FLY).
Q24500 RYANODINE RECEPTOR HOMOLOGUE - DROSOPHILA MELANOGASTER (FRUIT FLY).
Q24501 RYANODINE RECEPTOR HOMOLOGUE - DROSOPHILA MELANOGASTER (FRUIT FLY).
Q29104 RYANODINE RECEPTOR - SUS SCROFA (PIG).
Q29105 RYANODINE RECEPTOR - SUS SCROFA (PIG).
Q29621 CARDIAC RYANODINE RECEPTOR - ORYCTOLAGUS CUNICULUS (RABBIT).
Q90985 RYANODINE RECEPTOR TYPE 3 - GALLUS GALLUS (CHICKEN).
Q91313 ALPHA-RYANODINE BINDING PROTEIN - RANA CATESBEIANA (BULL FROG).
Q91319 BETA-RYANODINE BINDING PROTEIN - RANA CATESBEIANA (BULL FROG).
Q92736 RYANODINE RECEPTOR 2 - HOMO SAPIENS (HUMAN).
Q95201 RYANODINE RECEPTOR TYPE 3 - MUSTELA VISON (AMERICAN MINK).
RYNC_RABIT RYANODINE RECEPTOR, CARDIAC MUSCLE - ORYCTOLAGUS CUNICULUS (RABBIT).
RYNR_HUMAN RYANODINE RECEPTOR, SKELETAL MUSCLE (SKELETAL MUSCLE CALCIUM RELEASE CHANNEL) - HOMO SAPIENS (HUMAN).
RYNR_PIG RYANODINE RECEPTOR, SKELETAL MUSCLE (SKELETAL MUSCLE CALCIUM RELEASE CHANNEL) - SUS SCROFA (PIG).
RYNR_RABIT RYANODINE RECEPTOR, SKELETAL MUSCLE (SKELETAL MUSCLE CALCIUM RELEASE CHANNEL) - ORYCTOLAGUS CUNICULUS (RABBIT).

Q94279 PARTIAL CDS - CAENORHABDITIS ELEGANS.
Scan History
OWL29_4    2  100  NSINGLE    
SPTR37_9f 2 59 NSINGLE
Initial Motifs
Motif 1  width=22
Element Seqn Id St Int Rpt
PPDLAICCFVLEQSLSVRALQE RYNR_HUMAN 58 58 -
PPDLAICCFVLEQSLSVRALQE RYNR_PIG 59 59 -
PPDLAICCFVLEQSLSVRALQE I46645 59 59 -
PPDLCVCNFVLEQSLSVRALQE MVRYR3 60 60 -
PPDLCVCNFVLEQSLSVRALQE S27272 60 60 -
PPDLCICNFVLEQSLSVRALQE S66572 60 60 -
PPDLAICCFVLEQSLSVRALQE I46646 59 59 -
PPDLSICTFVLEQSLLVRALQE RYNC_RABIT 59 59 -
PPDLAICCFTLEQSLSVRALQE RYNR_RABIT 59 59 -

Motif 2 width=19
Element Seqn Id St Int Rpt
GGHRTLLYGHAILLRHSFS MVRYR3 98 16 -
GGHRTLLYGHAILLRHSYS RYNC_RABIT 108 27 -
GGHRTLLYGHAILLRHAHS RYNR_RABIT 96 15 -
GGHRTLLYGHAILLRHAHS I46645 96 15 -
GGHRTLLYGHAILLRHAHS RYNR_HUMAN 95 15 -
GGHRTLLYGHAILLRHAHS I46646 96 15 -
GGHRTLLYGHAILLRHSFS S66572 97 15 -
GGHRTLLYGHAILLRHAHS RYNR_PIG 96 15 -
GGHRTLLYGHAILLRHSFS S27272 98 16 -

Motif 3 width=25
Element Seqn Id St Int Rpt
KQRSEGEKVRIGDDLILVSVSSERY S66572 156 40 -
KQRSEGEKVRVGDDLILVSVSSERY RYNR_RABIT 155 40 -
KQRSEGEKVRVGDDLILVSVSSERY RYNC_RABIT 167 40 -
KQRSEGEKVRVGDDLILVSVSSERY I46645 155 40 -
KQRSEGEKVRVGDDLILVSVSSERY I46646 155 40 -
KQRSEGEKVRVGDDIILVSVSSERY RYNR_HUMAN 154 40 -
KQRSEGEKVRIGDDLILVSVSSERY S27272 157 40 -
KQRSEGEKVRIGDDLILVSVSSERY MVRYR3 157 40 -
KQRSEGEKVRVGDDLILVSVSSERY RYNR_PIG 155 40 -

Motif 4 width=24
Element Seqn Id St Int Rpt
RARSLWRVDPLRISWSGSNIRWGQ MVRYR3 259 77 -
RARSLWRVEPLRISWSGSNIRWGQ S27272 259 77 -
RARSLWRVEPLRISWSGSNIRWGQ S66572 258 77 -
HARSLWRLEPLRISWSGSHLRWGQ I46646 255 75 -
HARSLWRLEPLRISWSGSHLRWGQ I46645 255 75 -
HARSLWRLEPLRISWSGSHLRWGQ RYNR_RABIT 255 75 -
HARSLWRLEPLRISWSGSHLRWGQ RYNR_HUMAN 254 75 -
HARSLWRLEPLRISWSGSHLRWGQ RYNR_PIG 255 75 -
HARSLWRLETLRVAWSGSHIRWGQ RYNC_RABIT 270 78 -

Motif 5 width=20
Element Seqn Id St Int Rpt
GILEVLHCILIESPEALNLI MVRYR3 557 274 -
GILEVLHCILIESPEALNLI S27272 557 274 -
GILEVLHCILIESPEALNII S66572 556 274 -
GILEVLYCVLIESPEVLNII I46646 559 280 -
GILEVLHCVLVESPEALNII RYNC_RABIT 570 276 -
GILEVLYCVLIESPEVLNII RYNR_RABIT 559 280 -
GILEVLYCVLIESPEVLNII RYNR_HUMAN 558 280 -
GILEVLYCVLIESPEVLNII RYNR_PIG 559 280 -
GILEVLYCVLIESPEVLNII I46645 559 280 -

Motif 6 width=23
Element Seqn Id St Int Rpt
WGGNGVGDDLYSYGFDGLHLWTG I46646 702 123 -
WGGNGVGDDLYSYGFDGLHLWSG S27272 700 123 -
WGGNGVGDDLYSYGFDGLHLWSG MVRYR3 700 123 -
WGGNGVGDDLYSYGFDGLHLWTG I46645 702 123 -
WGGNGVGDDLFSYGFDGLHLWSG RYNC_RABIT 713 123 -
WGGNGVGDDLYSYGFDGLHLWTG RYNR_RABIT 702 123 -
WGGNGVGDDLYSYGFDGLHLWTG RYNR_HUMAN 701 123 -
WGGNGVGDDLYSYGFDGLHLWTG RYNR_PIG 702 123 -
WGGNGVGDDLYSFGFDGLHLWSG S66572 699 123 -

Motif 7 width=21
Element Seqn Id St Int Rpt
SAGVKVRFLLGGRHGEFKFLP RYNR_HUMAN 783 59 -
SAGVKVRFLLGGRHGEFKFLP I46645 784 59 -
SAGVKVRFLLGGRHGEFKFLP I46646 784 59 -
SAGVKARFLLGGRHGEFKFLP S66572 781 59 -
SAGVKVRFLMGGRHGEFKFLP S27272 782 59 -
SAGVKVRFLTGGRHGEFKFLP MVRYR3 782 59 -
SAGVKVRFLLGGRHGEFKFLP RYNR_PIG 784 59 -
SAGVKVRFLLGGRHGEFKFLP RYNR_RABIT 784 59 -
SAGIKVRFLLGGRHGEFKFLP RYNC_RABIT 795 59 -

Motif 8 width=24
Element Seqn Id St Int Rpt
RDKLAENIHELWGMNKIELGWTYG S66572 868 66 -
REKLAENIHELWALTRIEQGWTYG RYNR_PIG 871 66 -
REKLAENIHELWALTRIEQGWTYG RYNR_HUMAN 870 66 -
REKLAENIHELWALTRIEQGWTYG RYNR_RABIT 871 66 -
REKLAENIHELWVMNKIELGWQYG RYNC_RABIT 882 66 -
REKLAENIHELWALTRIEQGWTYG I46646 871 66 -
RDRLAENIHELWGMNKIELGWTFG MVRYR3 869 66 -
REKLAENIHELWALTRIEQGWTYG I46645 871 66 -
RDRLAENIHELWGMNKIELGWTFG S27272 869 66 -

Motif 9 width=22
Element Seqn Id St Int Rpt
QGWTYGIQQDLKNKRNPRLVPY S66572 1000 108 -
QGWSYSAVQDIPARRNPRLVPY I46645 1003 108 -
QGWSYSAVQDIPARRNPRLVPY RYNR_HUMAN 1002 108 -
QGWSYSAVQDIPARRNPRLVPY RYNR_RABIT 1003 108 -
QGWTYGIQQDVKNRRNPRLVPY RYNC_RABIT 1014 108 -
QGWSYSAVQDIPARRNPRLVPY RYNR_PIG 1003 108 -
QGWTYGIQQDLKNKRNPRLVPY MVRYR3 1001 108 -
QGWTYGIQQDLKNKRNPRLVPY S27272 1001 108 -
QGWSYSAVQDIPARRNPRLVPY I46646 1003 108 -
Final Motifs
Motif 1  width=22
Element Seqn Id St Int Rpt
PPDLAICCFVLEQSLSVRALQE Q29104 59 59 -
PPDLAICCFVLEQSLSVRALQE Q29105 59 59 -
PPDLAICCFVLEQSLSVRALQE RYNR_PIG 59 59 -
PPDLAICCFVLEQSLSVRALQE RYNR_HUMAN 58 58 -
PPDLAICCFTLEQSLSVRALQE RYNR_RABIT 59 59 -
PPDLSICTFVLEQSLSVRALQE Q29621 59 59 -
PPDLSICTFVLEQSLSVRALQE Q92736 59 59 -
PPDLSICTFVLEQSLLVRALQE RYNC_RABIT 59 59 -
PPDLCICNFVLEQSLSVRALQE Q90985 60 60 -
PPDLCICNFVLEQSLSVRALQE Q91319 59 59 -
PPDLAICCFILEQSLSVRALQE O13054 59 59 -
PPDLAICCFILEQSLSVRALQE Q91313 59 59 -
PPDLCVCNFVLEQSLSVRALQE Q95201 60 60 -
PPDLSQCVFVIEQALSVRALQE Q24498 56 56 -
PPDLSQCVFVIEQALSVRALQE Q24499 56 56 -
PPDLSQCVFVIEQALSVRALQE Q24500 56 56 -
PPDLSQCVFVIEQALSVRALQE Q24501 56 56 -
PPDIAMCMLYIDNALSMRALQE P91905 66 66 -

Motif 2 width=19
Element Seqn Id St Int Rpt
GGHRTLLYGHAILLRHAHS Q29104 96 15 -
GGHRTLLYGHAILLRHAHS Q29105 96 15 -
GGHRTLLYGHAILLRHAHS RYNR_PIG 96 15 -
GGHRTLLYGHAILLRHAHS RYNR_HUMAN 95 15 -
GGHRTLLYGHAILLRHAHS RYNR_RABIT 96 15 -
GGHRTLLYGHAILLRHSYS Q29621 108 27 -
GGHRTLLYGHAILLRHSYS Q92736 108 27 -
GGHRTLLYGHAILLRHSYS RYNC_RABIT 108 27 -
GGHRTLLYGHAILLRHSFS Q90985 97 15 -
GGHRTLLYGHAILLRHSFS Q91319 97 16 -
GGHRTLLYGHAILLKHTHS O13054 101 20 -
GGHRTLLYGHAILLRHCHS Q91313 96 15 -
GGHRTLLYGHAILLRHSFS Q95201 98 16 -
SGHRTLLYGNAILLRHHNS Q24498 92 14 -
SGHRTLLYGNAILLRHHNS Q24499 92 14 -
SGHRTLLYGNAILLRHHNS Q24500 92 14 -
SGHRTLLYGNAILLRHHNS Q24501 92 14 -
GGHKTLLYGHAVQLKHVQS P91905 102 14 -

Motif 3 width=25
Element Seqn Id St Int Rpt
KQRSEGEKVRVGDDLILVSVSSERY Q29104 155 40 -
KQRSEGEKVRVGDDLILVSVSSERY Q29105 155 40 -
KQRSEGEKVRVGDDLILVSVSSERY RYNR_PIG 155 40 -
KQRSEGEKVRVGDDIILVSVSSERY RYNR_HUMAN 154 40 -
KQRSEGEKVRVGDDLILVSVSSERY RYNR_RABIT 155 40 -
KQRSEGEKVRVGDDLILVSVSSERY Q29621 167 40 -
KQRSEGEKVRVGDDLILVSVSSERY Q92736 167 40 -
KQRSEGEKVRVGDDLILVSVSSERY RYNC_RABIT 167 40 -
KQRSEGEKVRIGDDLILVSVSSERY Q90985 156 40 -
KQRSEGEKVRIGDDLILVSVSSERY Q91319 156 40 -
KQRSEGEKVRVGDDLILVSVSSERY O13054 160 40 -
KQRSEGEKVRIGDDLILVSVSSERY Q91313 155 40 -
KQRSEGEKVRIGDDLILVSVSSERY Q95201 157 40 -
KQRSEGEKVRVGDDLILVSVATERY Q24498 150 39 -
KQRSEGEKVRVGDDLILVSVATERY Q24499 150 39 -
KQRSEGEKVRVGDDLILVSVATERY Q24500 150 39 -
KQRSEGEKVRVGDDLILVSVATERY Q24501 150 39 -
KQRSEGEKVRVGDDVILVSVATERY P91905 160 39 -

Motif 4 width=24
Element Seqn Id St Int Rpt
HARSLWRLEPLRISWSGSHLRWGQ Q29104 255 75 -
HARSLWRLEPLRISWSGSHLRWGQ Q29105 255 75 -
HARSLWRLEPLRISWSGSHLRWGQ RYNR_PIG 255 75 -
HARSLWRLEPLRISWSGSHLRWGQ RYNR_HUMAN 254 75 -
HARSLWRLEPLRISWSGSHLRWGQ RYNR_RABIT 255 75 -
HARSLWRLETLRVAWSGSHIRWGQ Q29621 270 78 -
HARSLWRLETLRVAWSGSHIRWGQ Q92736 270 78 -
HARSLWRLETLRVAWSGSHIRWGQ RYNC_RABIT 270 78 -
RARSLWRVEPLRISWSGSNIRWGQ Q90985 258 77 -
RARSLWRVEPLRISWSGSHIRWGQ Q91319 260 79 -
HARSLWRLEPLRIAWSGGHIKWGQ O13054 263 78 -
HARSLWRSEPLRISWSGSHMRWGM Q91313 258 78 -
RARSLWRVDPLRISWSGSNIRWGQ Q95201 259 77 -
QARSLWRLELARTKWTGGFINWYH Q24498 254 79 -
QARSLWRLELARTKWTGGFINWYH Q24499 254 79 -
QARSLWRLELARTKWTGGFINWYH Q24500 254 79 -
QARSLWRLELARTKWTGGFINWYH Q24501 254 79 -
QARSLWRVELIRMKWHGALVGWEQ P91905 263 78 -

Motif 5 width=20
Element Seqn Id St Int Rpt
GILEVLYCVLIESPEVLNII Q29104 559 280 -
GILEVLYCVLIESPEVLNII Q29105 559 280 -
GILEVLYCVLIESPEVLNII RYNR_PIG 559 280 -
GILEVLYCVLIESPEVLNII RYNR_HUMAN 558 280 -
GILEVLYCVLIESPEVLNII RYNR_RABIT 559 280 -
GILEVLHCVLVESPEALNII Q29621 570 276 -
GILEVLHCVLVESPEALNII Q92736 570 276 -
GILEVLHCVLVESPEALNII RYNC_RABIT 570 276 -
GILEVLHCILIESPEALNII Q90985 556 274 -
GILEVLHSILIESPEALNLI Q91319 562 278 -
GILEVLYCVLIESPEVLNII O13054 564 277 -
GILEVLYCVLIESPEVLNII Q91313 559 277 -
GILEVLHCILIESPEALNLI Q95201 557 274 -
GMLDVLHCVLIDSPEALNMM Q24498 562 284 -
GMLDVLHCVLIDSPEALNMM Q24499 562 284 -
GMLDVLHCVLIDSPEALNMM Q24500 562 284 -
GMLDVLHCVLIDSPEALNMM Q24501 562 284 -
GILDVLYCVLTESPEALNMI P91905 568 281 -

Motif 6 width=23
Element Seqn Id St Int Rpt
WGGNGVGDDLYSYGFDGLHLWTG Q29104 702 123 -
WGGNGVGDDLYSYGFDGLHLWTG Q29105 702 123 -
WGGNGVGDDLYSYGFDGLHLWTG RYNR_PIG 702 123 -
WGGNGVGDDLYSYGFDGLHLWTG RYNR_HUMAN 701 123 -
WGGNGVGDDLYSYGFDGLHLWTG RYNR_RABIT 702 123 -
WGGNGVGDDLFSYGFDGLHLWSG Q29621 713 123 -
WGGNGVGDDLFSYGFDGLHLWSG Q92736 713 123 -
WGGNGVGDDLFSYGFDGLHLWSG RYNC_RABIT 713 123 -
WGGNGVGDDLYSFGFDGLHLWSG Q90985 699 123 -
WGGNGVGDDLFSYGFDGLHLWSG Q91319 705 123 -
WGGNGVGDDLYSYGFDGLHLWSG O13054 707 123 -
WGANGAGDDLYSFAFDGLHLWSG Q91313 702 123 -
WGGNGVGDDLYSYGFDGLHLWSG Q95201 700 123 -
WGGNGVGDDLYSFGFDGAFLWTG Q24498 704 122 -
WGGNGVGDDLYSFGFDGAFLWTG Q24499 704 122 -
WGGNGVGDDLYSFGFDGAFLWTG Q24500 704 122 -
WGGNGVGDDLYSFGFDGAFLWTG Q24501 704 122 -
MGCNGVGDDFYSYGFDGKSMYFG P91905 710 122 -

Motif 7 width=21
Element Seqn Id St Int Rpt
SAGVKVRFLLGGRHGEFKFLP Q29104 784 59 -
SAGVKVRFLLGGRHGEFKFLP Q29105 784 59 -
SAGVKVRFLLGGRHGEFKFLP RYNR_PIG 784 59 -
SAGVKVRFLLGGRHGEFKFLP RYNR_HUMAN 783 59 -
SAGVKVRFLLGGRHGEFKFLP RYNR_RABIT 784 59 -
SAGIKVRFLLGGRHGEFKFLP Q29621 795 59 -
SAGIKVRFLLGGRHGEFKFLP Q92736 795 59 -
SAGIKVRFLLGGRHGEFKFLP RYNC_RABIT 795 59 -
SAGVKARFLLGGRHGEFKFLP Q90985 781 59 -
SAGVKVRFLLGGRHGEFKFLP Q91319 787 59 -
SAGVKLRFLLGGRHGDFKFLP O13054 789 59 -
SPGIKIRFLLGGRHGEFKFLP Q91313 784 59 -
SAGVKVRFLTGGRHGEFKFLP Q95201 782 59 -
SSKLSCRFLFGGDHGRLKFAP Q24498 788 61 -
SSKLSCRFLFGGDHGRLKFAP Q24499 788 61 -
SSKLSCRFLFGGDHGRLKFAP Q24500 788 61 -
SSKLSCRFLFGGDHGRLKFAP Q24501 788 61 -
SAKVSCRFILGGNQGRLRYGP P91905 789 56 -

Motif 8 width=24
Element Seqn Id St Int Rpt
REKLAENIHELWALTRIEQGWTYG Q29104 871 66 -
REKLAENIHELWALTRIEQGWTYG Q29105 871 66 -
REKLAENIHELWALTRIEQGWTYG RYNR_PIG 871 66 -
REKLAENIHELWALTRIEQGWTYG RYNR_HUMAN 870 66 -
REKLAENIHELWALTRIEQGWTYG RYNR_RABIT 871 66 -
REKLAENIHELWVMNKIELGWQYG Q29621 882 66 -
REKLAENIHELWVMNKIELGWQYG Q92736 882 66 -
REKLAENIHELWVMNKIELGWQYG RYNC_RABIT 882 66 -
RDKLAENIHELWGMNKIELGWTYG Q90985 868 66 -
RDKLAENIHELWGMNKIELGWIYG Q91319 874 66 -
REKLAENSHELWAVTRIEQGWTYG O13054 876 66 -
REKLAENIHELWALTRIEQGWTYG Q91313 871 66 -
RDRLAENIHELWGMNKIELGWTFG Q95201 869 66 -
KEKLAENIHEMWALNKIEAGWSWG Q24498 873 64 -
KEKLAENIHEMWALNKIEAGWSWG Q24499 873 64 -
KEKLAENIHEMWALNKIEAGWSWG Q24500 873 64 -
KEKLAENIHEMWALNKIEAGWSWG Q24501 873 64 -
HQKYAENLHELWAMRKIELGWSYG P91905 873 63 -

Motif 9 width=22
Element Seqn Id St Int Rpt
QGWSYSAVQDIPARRNPRLVPY Q29104 1003 108 -
QGWSYSAVQDIPARRNPRLVPY Q29105 1003 108 -
QGWSYSAVQDIPARRNPRLVPY RYNR_PIG 1003 108 -
QGWSYSAVQDIPARRNPRLVPY RYNR_HUMAN 1002 108 -
QGWSYSAVQDIPARRNPRLVPY RYNR_RABIT 1003 108 -
QGWTYGIQQDVKNRRNPRLVPY Q29621 1014 108 -
QGWTYGIQQDVKNRRNPRLVPY Q92736 1014 108 -
QGWTYGIQQDVKNRRNPRLVPY RYNC_RABIT 1014 108 -
QGWTYGIQQDLKNKRNPRLVPY Q90985 1000 108 -
QGWTYGIQQDLKNKRNPRLVPY Q91319 1006 108 -
QGWTYSIVQDILNKRNPRLVPY O13054 1008 108 -
QGWTYSIIQDIKNKRNPRLVPY Q91313 1003 108 -
QGWTYGIQQDLKNKRNPRLVPY Q95201 1001 108 -
QGWTYGLNEDSENHRSPHLVPY Q24498 1004 107 -
QGWTYGLNEDSENHRSPHLVPY Q24499 1004 107 -
QGWTYGLNEDSENHRSPHLVPY Q24500 1004 107 -
QGWTYGLNEDSENHRSPHLVPY Q24501 1004 107 -
WTFGLSEHVDATQKRSPHLVPY P91905 1005 108 -