SPRINT Home UMBER Home Contents Standard Search Advanced Search Relation Search

==SPRINT==> PRINTS View



  selected as


PR00779

Identifier
INSP3RECEPTR  [View Relations]  [View Alignment]  
Accession
PR00779
No. of Motifs
9
Creation Date
22-AUG-1997  (UPDATE 07-JUN-1999)
Title
Inositol 1,4,5-trisphosphate-binding protein receptor signature
Database References

INTERPRO; IPR000493
Literature References
1. SUDHOF, T.C., NEWTON, C.L., ARCHER, B.T.III, USHKARYOV, Y.A.
AND MIGNERY, G.A.
Structure of a novel InsP3 receptor.
EMBO J. 10(11) 3199-3206 (1991).
 
2. MIGNERY, G.A., NEWTON, C.L., ARCHER, B.T.III AND SUDHOF, T.C.
Structure and expression of the rat inositol 1,4,5-trisphosphate receptor.
J.BIOL.CHEM. 265 12679-12685 (1990).
 
3. WITCHER, D.R., KOVACS, R.J., SCHULMAN, H., CEFALI, D.C. AND JONES, L.R.
Unique phosphorylation site on the cardiac ryanodine receptor regulates
calcium channel activity.
J.BIOL.CHEM. 266 11144-11152 (1991).

Documentation
Inositol 1,4,5-trisphosphate (InsP3) is an intracellular second messenger 
that transduces growth factor and neurotransmitter signals. InsP3 mediates 
the release of Ca2+ from intracellular stores by binding to specific Ca2+ 
channel-coupled receptors. One such receptor contains a C-terminal Ca2+ 
channel with 8 possible transmembrane (TM) regions, while its N-terminal 
cytoplasmic region houses ligand-binding and modulatory sites [1,2]. Ca2+
appears to inhibit ligand binding, possibly by interacting with a Ca2+-
binding protein that itself inhibits the receptor.
 
The InsP3 receptor is an integral membrane protein located in the
endoplasmic reticulum. It is a homotetramer. The protein shows some
similarity to the ryanodine receptor, which functions as a Ca2+-release
channel in the sarcoplasmic reticulum of cardiac and skeletal muscle [3].
 
INSP3RECEPTR is a 9-element fingerprint that provides a signature for
InsP3 receptors. The fingerprint was derived from an initial alignment
of 11 sequences - the motifs were drawn from conserved regions spanning
the N-terminal third of the alignment. A single iteration on OWL29.4 was
required to reach convergence, no further sequences being identified
beyond the starting set. Two partial matches were found, S27272 and
MVRYR3, both of which are ryanodine receptors that match motifs 3 and 4.
 
An update on SPTR37_9f identified a true set of 15 sequences.
Summary Information
15 codes involving  9 elements
0 codes involving 8 elements
0 codes involving 7 elements
0 codes involving 6 elements
0 codes involving 5 elements
0 codes involving 4 elements
0 codes involving 3 elements
0 codes involving 2 elements
Composite Feature Index
9151515151515151515
8000000000
7000000000
6000000000
5000000000
4000000000
3000000000
2000000000
123456789
True Positives
IP3R_DROME    IP3R_MOUSE    IP3R_RAT      IP3S_HUMAN    
IP3S_RAT O61193 O61194 O61195
O77089 Q14573 Q14643 Q14649
Q14660 Q63269 Q91908
Sequence Titles
IP3R_DROME  INOSITOL 1,4,5-TRISPHOSPHATE-BINDING PROTEIN RECEPTOR (INSP3 RECEPTOR) (INSP3R) - DROSOPHILA MELANOGASTER (FRUIT FLY). 
IP3R_MOUSE INOSITOL 1,4,5-TRISPHOSPHATE-BINDING PROTEIN TYPE 1 RECEPTOR (INOSITOL 1,4,5-TRISPHOSPHATE-BINDING PROTEIN P(400)) (TYPE 1 INSP3 RECEPTOR) - MUS MUSCULUS (MOUSE).
IP3R_RAT INOSITOL 1,4,5-TRISPHOSPHATE-BINDING PROTEIN TYPE 1 RECEPTOR (INOSITOL 1,4,5-TRISPHOSPHATE-BINDING PROTEIN P(400)) (TYPE 1 INSP3 RECEPTOR) - RATTUS NORVEGICUS (RAT).
IP3S_HUMAN INOSITOL 1,4,5-TRISPHOSPHATE-BINDING PROTEIN TYPE 2 RECEPTOR (TYPE 2 INSP3 RECEPTOR) (TYPE 2 INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR) - HOMO SAPIENS (HUMAN).
IP3S_RAT INOSITOL 1,4,5-TRISPHOSPHATE-BINDING PROTEIN TYPE 2 RECEPTOR (TYPE 2 INSP3 RECEPTOR) (TYPE 2 INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR) - RATTUS NORVEGICUS (RAT).
O61193 F33D4.2A PROTEIN - CAENORHABDITIS ELEGANS.
O61194 F33D4.2B PROTEIN - CAENORHABDITIS ELEGANS.
O61195 F33D4.2C PROTEIN - CAENORHABDITIS ELEGANS.
O77089 INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR - PANULIRUS ARGUS (SPINY LOBSTER).
Q14573 HUMAN TYPE 3 INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR - HOMO SAPIENS (HUMAN).
Q14643 HUMAN TYPE 1 INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR - HOMO SAPIENS (HUMAN).
Q14649 TYPE 3 INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR - HOMO SAPIENS (HUMAN).
Q14660 INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 1 - HOMO SAPIENS (HUMAN).
Q63269 INOSITOL TRIPHOSPHATE RECEPTOR SUBTYPE 3 - RATTUS NORVEGICUS (RAT).
Q91908 INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
Scan History
OWL29_4    1  50   NSINGLE    
SPTR37_9f 2 16 NSINGLE
Initial Motifs
Motif 1  width=24
Element Seqn Id St Int Rpt
KKFRDCLFKVCPMNRYSAQKQYWK A49873 50 50 -
KKFRDCLFKVCPMNRYSAQKQYWK A46719 50 50 -
KKFRDCLFKLCPMNRYSAQKQFWK S54974 51 51 -
KKFRDCLFRLCPMNRYSAQKQFWK A40743 51 51 -
KKFRDCLFKVCPMNRYSAQKQYWK HUMHT3I 50 50 -
KKFRDCLFKVCPMNRYSAQKQYWK HUMHT2I 51 51 -
KKFRDCLIKICPMNRYSAQKQFWK IP3R_DROME 54 54 -
KKFRDCLFKVCPMNRYSAQKQYWK IP3S_RAT 51 51 -
KKFRDCLFKLCPMNRYSAQKQFWK IP3R_RAT 51 51 -
KKFRDCLFKLCPMNRYSAQKQFWK IP3R_MOUSE 51 51 -
KKFRDCLFKLCPMNRYSAQKQFWK A55713 51 51 -

Motif 2 width=20
Element Seqn Id St Int Rpt
KYLTVNKRLPSLLEKNAMRV IP3R_DROME 134 56 -
KYLTVNKRLPALLEKNAMRV A55713 130 55 -
KYLTVNKRLPALLEKNAMRV S54974 130 55 -
KYLTVNKRLPALLEKNAMRV A46719 131 57 -
KYLTVNKRLPALLEKNAMRV A49873 131 57 -
KYLTVNKRLPALLEKNAMRV HUMHT2I 130 55 -
KYLTVNKRLPALLEKNAMRV HUMHT3I 131 57 -
KYLTVNKRLPALLEKNAMRV A40743 130 55 -
KYLTVNKRLPALLEKNAMRV IP3S_RAT 130 55 -
KYLTVNKRLPALLEKNAMRV IP3R_RAT 130 55 -
KYLTVNKRLPALLEKNAMRV IP3R_MOUSE 130 55 -

Motif 3 width=21
Element Seqn Id St Int Rpt
KGGDVVRLFHAEQEKFLTCDE IP3R_MOUSE 235 85 -
KGGDVVRLFHAEQEKFLTCDE A55713 235 85 -
KGGDVVRLFHAEQEKFLTCDE S54974 235 85 -
KGGDVVRLFHAEQEKFLTCDE A46719 236 85 -
KGGDVVRLFHAEQEKFLTCDE A49873 236 85 -
KGGDVVRLFHAEQEKFLTCDE HUMHT2I 235 85 -
KGGDVVRLFHAEQEKFLTCDE HUMHT3I 236 85 -
KGGDVVRLFHAEQEKFLTCDE A40743 235 85 -
KGGDVVRLFHAEQEKFLTMDE IP3R_DROME 242 88 -
KGGDVVRLFHAEQEKFLTCDD IP3S_RAT 235 85 -
KGGDVVRLFHAEQEKFLTCDE IP3R_RAT 235 85 -

Motif 4 width=25
Element Seqn Id St Int Rpt
HDPCRGGAGHWNGLYRFKHLATGNY HUMHT3I 290 33 -
HDPCRGGAGQWNSLFRFKHLATGNY HUMHT2I 289 33 -
HDPCRGGAGHWNGLYRFKHLATGNY A49873 290 33 -
HDSCRGGAGDWNSLYRFKHLATGHY IP3R_DROME 296 33 -
HDPCRGGAGQWNSLFRFKHLATGNY IP3S_RAT 289 33 -
HDPCRGGAGYWNSLFRFKHLATGHY IP3R_RAT 289 33 -
HDPCRGGAGYWNSLFRFKHLATGHY IP3R_MOUSE 289 33 -
HDPCRGGAGYWNSLFRFKHLATGHY A55713 289 33 -
HDPCRGGAGHWNGLYRFKHLATGNY A46719 290 33 -
HDPCRGGAGYWNSLFRFKHLATGHY S54974 289 33 -
HDPCRGGAGYWNSLFRFKHLATGHY A40743 289 33 -

Motif 5 width=26
Element Seqn Id St Int Rpt
KEDKEAFAIVSVPLSEVRDLDFANDA HUMHT2I 423 109 -
KEDKEAFAIVPVSPAEVRDLDFANDA A40743 409 95 -
KEDKEAFAIVPVSPAEVRDLDFANDA S54974 409 95 -
KEDKEAFGIVPVSPAEVRDLDFANDA A55713 424 110 -
KEDKEAFALIPVSPVEVRDLDFANDA IP3R_DROME 444 123 -
KEDKEAFAIVCVPLSEVRDLDFANDA IP3S_RAT 423 109 -
KEDKEAFAIVPVSPAEVRDLDFANDA IP3R_RAT 424 110 -
KEDKEAFAIVPVSPAEVRDLDFANDA IP3R_MOUSE 424 110 -
KEDKEAFAIVSVPVSEIRDLDFANDA A46719 423 108 -
KEDKEAFAIVSVPVSEIRDLDFANDA A49873 423 108 -
KEDKEAFAIVSVPVSEIRDLDFANDA HUMHT3I 423 108 -

Motif 6 width=23
Element Seqn Id St Int Rpt
RLCYRILRLSQQDYRKNQEYIAK IP3R_DROME 578 108 -
RLCYRVLRHSQQDYRKNQEYIAK A55713 554 104 -
RLCYRVLRHSQQDYRKNQEYIAK S54974 539 104 -
RLCYRVLRHSQEDYRKNQEHIAK A46719 554 105 -
RLCYRVLRYSQEDYRKNQEHIAK A49873 554 105 -
RLCYRVLRHSQQDYRKNQEYIAK HUMHT2I 554 105 -
RLCYRVLRHSQEDYRKNQEHIAK HUMHT3I 554 105 -
RLCYRVLRHSQQDYRKNQEYIAK A40743 539 104 -
RLCYRVLRHSQQDYRKNQEYIAK IP3R_MOUSE 554 104 -
RLCYRVLRHSQQDYRKNQEYIAK IP3R_RAT 554 104 -
RLCYRVLRHSQQDYRKNQEYIAK IP3S_RAT 554 105 -

Motif 7 width=25
Element Seqn Id St Int Rpt
GYDVLAEDTITALLHNNRKLLEKHI IP3R_MOUSE 586 9 -
GYDILAEDTITALLHNNRKLLEKHI IP3S_RAT 586 9 -
GYDILAEDTITALLHNNRKLLEKHI IP3R_DROME 610 9 -
GYDVLAEDTITALLHNNRKLLEKHI A40743 571 9 -
GYDILAEDTITALLHNNRKLLEKHI HUMHT3I 586 9 -
GYDILAEDTITPLLHNNRKLLEKHI HUMHT2I 586 9 -
GYDILAEDTITALLHNNRKLLEKHI A49873 586 9 -
GYDILAEDTITALLHNNRKLLEKHI A46719 586 9 -
GYDVLAEDTITALLHNNRKLLEKHI S54974 571 9 -
GYDVLAEDTITALLHNNRKLLEKHI A55713 586 9 -
GYDVLAEDTITALLHNNRKLLEKHI IP3R_RAT 586 9 -

Motif 8 width=22
Element Seqn Id St Int Rpt
LPFDLRASFCRLMLHMHVDRDP A40743 758 162 -
LPFDLRASFCHLMLHVHVDRDP HUMHT3I 769 158 -
LPFDLRASFCRLMLHMHVDRDP HUMHT2I 770 159 -
LPYDLRASFCRLMLHMHVDRDP IP3R_MOUSE 773 162 -
LPYDLRASFCRLMLHMHVDRDP IP3R_RAT 773 162 -
LPFDLRASFCRLMLHMHVDRDP IP3S_RAT 770 159 -
MPYELRASFCRLMLHLHVDRDP IP3R_DROME 836 201 -
LPFDLRASFCHLMLHVHVDRDP A49873 769 158 -
LPFDLRASFCHLMLHVHVDRDP A46719 769 158 -
LPYDLRASFCRLMLHMHVDRDP S54974 759 163 -
LPYDLRASFCRLMLHMHVDRDP A55713 774 163 -

Motif 9 width=26
Element Seqn Id St Int Rpt
FEVVHLARNLIYFGFYSFSELLRLTR HUMHT2I 862 70 -
FEVVSLAHNLIYFGFYSFSELLRLTR A46719 861 70 -
FEVVNLARNLIYFGFYNFSDLLRLTK S54974 850 69 -
FEVVNLARNLIYFGFYNFSDLLRLTK A55713 865 69 -
FEVVNLARNLIYFGFYNFSDLLRLTK IP3R_RAT 864 69 -
FEVVHLARNLIYFGFYSFSELLRLTR IP3S_RAT 862 70 -
FEVVKLARDLIYFGFYSFSDLLRLTK IP3R_DROME 931 73 -
FEVVNLARNLIYFGFYNFSDLLRLTK IP3R_MOUSE 864 69 -
FEVVNLARNLIYFGFYNFSDLLRLTK A40743 849 69 -
FEVVSLAHNLIYFGFYSFSELLRLTR HUMHT3I 861 70 -
FEVVSLAHNLIYFGFYSFSELLRLTR A49873 861 70 -
Final Motifs
Motif 1  width=24
Element Seqn Id St Int Rpt
KKFRDCLFKLCPMNRYSAQKQFWK IP3R_MOUSE 51 51 -
KKFRDCLFKLCPMNRYSAQKQFWK IP3R_RAT 51 51 -
KKFRDCLFKLCPMNRYSAQKQFWK Q14643 51 51 -
KKFRDCLFKLCPMNRYSAQKQFWK Q14660 51 51 -
KKFRDCLFRLCPMNRYSAQKQFWK Q91908 51 51 -
KKFRDCLFKVCPMNRYSAQKQYWK IP3S_HUMAN 51 51 -
KKFRDCLFKVCPMNRYSAQKQYWK IP3S_RAT 51 51 -
KKFRDCLFKVCPMNRYSAQKQYWK Q14573 50 50 -
KKFRDCLFKVCPMNRYSAQKQYWK Q63269 50 50 -
KKFRDCLFKVCPMNRYSAQKQYWK Q14649 50 50 -
KKFRDCLIKICPMNRYSAQKQFWK IP3R_DROME 54 54 -
KKFRDCLFSICPSNRYSAQKQFWK O77089 52 52 -
KKFRDCLFKVCPVNRYAAQKHLWT O61193 68 68 -
KKFRDCLFKVCPVNRYAAQKHLWT O61194 68 68 -
KKFRDCLFKVCPVNRYAAQKHLWT O61195 68 68 -

Motif 2 width=20
Element Seqn Id St Int Rpt
KYLTVNKRLPALLEKNAMRV IP3R_MOUSE 130 55 -
KYLTVNKRLPALLEKNAMRV IP3R_RAT 130 55 -
KYLTVNKRLPALLEKNAMRV Q14643 130 55 -
KYLTVNKRLPALLEKNAMRV Q14660 130 55 -
KYLTVNKRLPALLEKNAMRV Q91908 130 55 -
KYLTVNKRLPALLEKNAMRV IP3S_HUMAN 130 55 -
KYLTVNKRLPALLEKNAMRV IP3S_RAT 130 55 -
KYLTVNKRLPALLEKNAMRV Q14573 131 57 -
KYLTVNKRLPALLEKNAMRV Q63269 131 57 -
KYLTVNKRLPALLEKNAMRV Q14649 131 57 -
KYLTVNKRLPSLLEKNAMRV IP3R_DROME 134 56 -
KYLTVNKRLPALLEKNAMRV O77089 131 55 -
KYITVQKNSPAKRERNAMKV O61193 149 57 -
KYITVQKNSPAKRERNAMKV O61194 149 57 -
KYITVQKNSPAKRERNAMKV O61195 149 57 -

Motif 3 width=21
Element Seqn Id St Int Rpt
KGGDVVRLFHAEQEKFLTCDE IP3R_MOUSE 235 85 -
KGGDVVRLFHAEQEKFLTCDE IP3R_RAT 235 85 -
KGGDVVRLFHAEQEKFLTCDE Q14643 235 85 -
KGGDVVRLFHAEQEKFLTCDE Q14660 235 85 -
KGGDVVRLFHAEQEKFLTCDE Q91908 235 85 -
KGGDVVRLFHAEQEKFLTCDE IP3S_HUMAN 235 85 -
KGGDVVRLFHAEQEKFLTCDD IP3S_RAT 235 85 -
KGGDVVRLFHAEQEKFLTCDE Q14573 236 85 -
KGGDVVRLFHAEQEKFLTCDE Q63269 236 85 -
KGGDVVRLFHAEQEKFLTCDE Q14649 236 85 -
KGGDVVRLFHAEQEKFLTMDE IP3R_DROME 242 88 -
KGGDVIRLFHAEQEKFLTMDE O77089 237 86 -
KSGDVVRLFHADQQTFLTLDT O61193 262 93 -
KSGDVVRLFHADQQTFLTLDT O61194 262 93 -
KSGDVVRLFHADQQTFLTLDT O61195 262 93 -

Motif 4 width=25
Element Seqn Id St Int Rpt
HDPCRGGAGYWNSLFRFKHLATGHY IP3R_MOUSE 289 33 -
HDPCRGGAGYWNSLFRFKHLATGHY IP3R_RAT 289 33 -
HDPCRGGAGYWNSLFRFKHLATGHY Q14643 289 33 -
HDPCRGGAGYWNSLFRFKHLATGHY Q14660 289 33 -
HDPCRGGAGYWNSLFRFKHLATGHY Q91908 289 33 -
HDPCRGGAGQWNSLFRFKHLATGNY IP3S_HUMAN 289 33 -
HDPCRGGAGQWNSLFRFKHLATGNY IP3S_RAT 289 33 -
HDPCRGGAGHWNGLYRFKHLATGNY Q14573 290 33 -
HDPCRGGAGHWNGLYRFKHLATGNY Q63269 290 33 -
HDPCRGGAGHWNGLYRFKHLATGNY Q14649 290 33 -
HDSCRGGAGDWNSLYRFKHLATGHY IP3R_DROME 296 33 -
HDPSRGGAGHWNSLFRFKHLATGHY O77089 291 33 -
TNAYRGGTAKWNKAYRFKHLATDMY O61193 320 37 -
TNAYRGGTAKWNKAYRFKHLATDMY O61194 320 37 -
TNAYRGGTAKWNKAYRFKHLATDMY O61195 320 37 -

Motif 5 width=26
Element Seqn Id St Int Rpt
KEDKEAFAIVPVSPAEVRDLDFANDA IP3R_MOUSE 424 110 -
KEDKEAFAIVPVSPAEVRDLDFANDA IP3R_RAT 424 110 -
KEDKEAFAIVPVSPAEVRDLDFANDA Q14643 409 95 -
KEDKEAFGIVPVSPAEVRDLDFANDA Q14660 424 110 -
KEDKEAFAIVPVSPAEVRDLDFANDA Q91908 409 95 -
KEDKEAFAIVSVPLSEVRDLDFANDA IP3S_HUMAN 423 109 -
KEDKEAFAIVCVPLSEVRDLDFANDA IP3S_RAT 423 109 -
KEDKEAFAIVSVPVSEIRDLDFANDA Q14573 423 108 -
KEDKEAFAIVSVPVSEIRDLDFANDA Q63269 423 108 -
KEDKEAFAIVSVPVSEIRDLDFANDA Q14649 423 108 -
KEDKEAFALIPVSPVEVRDLDFANDA IP3R_DROME 444 123 -
KEDKEAFSLVPVHAKEVRDLDFAHDA O77089 413 97 -
RVDKETFALLPVNPDEASQSLNVRDL O61193 488 143 -
RVDKETFALLPVNPDEASQSLNVRDL O61194 488 143 -
RVDKETFALLPVNPDEASQSLNVRDL O61195 488 143 -

Motif 6 width=23
Element Seqn Id St Int Rpt
RLCYRVLRHSQQDYRKNQEYIAK IP3R_MOUSE 554 104 -
RLCYRVLRHSQQDYRKNQEYIAK IP3R_RAT 554 104 -
RLCYRVLRHSQQDYRKNQEYIAK Q14643 539 104 -
RLCYRVLRHSQQDYRKNQEYIAK Q14660 554 104 -
RLCYRVLRHSQQDYRKNQEYIAK Q91908 539 104 -
RLCYRVLRHSQQDYRKNQEYIAK IP3S_HUMAN 554 105 -
RLCYRVLRHSQQDYRKNQEYIAK IP3S_RAT 554 105 -
RLCYRVLRHSQEDYRKNQEHIAK Q14573 554 105 -
RLCYRVLRHSQEDYRKNQEHIAK Q63269 554 105 -
RLCYRVLRYSQEDYRKNQEHIAK Q14649 554 105 -
RLCYRILRLSQQDYRKNQEYIAK IP3R_DROME 578 108 -
RLCYRLLRLAQQGYRKNQEHIAQ O77089 549 110 -
QLCYCLLKYSQVSYRKNQEFLAE O61193 630 116 -
QLCYCLLKYSQVSYRKNQEFLAE O61194 630 116 -
QLCYCLLKYSQVSYRKNQEFLAE O61195 630 116 -

Motif 7 width=25
Element Seqn Id St Int Rpt
GYDVLAEDTITALLHNNRKLLEKHI IP3R_MOUSE 586 9 -
GYDVLAEDTITALLHNNRKLLEKHI IP3R_RAT 586 9 -
GYDVLAEDTITALLHNNRKLLEKHI Q14643 571 9 -
GYDVLAEDTITALLHNNRKLLEKHI Q14660 586 9 -
GYDVLAEDTITALLHNNRKLLEKHI Q91908 571 9 -
GYDILAEDTITPLLHNNRKLLEKHI IP3S_HUMAN 586 9 -
GYDILAEDTITALLHNNRKLLEKHI IP3S_RAT 586 9 -
GYDILAEDTITALLHNNRKLLEKHI Q14573 586 9 -
GYDILAEDTITALLHNNRKLLEKHI Q63269 586 9 -
GYDILAEDTITALLHNNRKLLEKHI Q14649 586 9 -
GYDILAEDTITALLHNNRKLLEKHI IP3R_DROME 610 9 -
GIDILAEETITALLHNNRKLLEIHI O77089 581 9 -
GFDLMAEDTMTAVLHNNPKLLEKYV O61193 662 9 -
GFDLMAEDTMTAVLHNNPKLLEKYV O61194 662 9 -
GFDLMAEDTMTAVLHNNPKLLEKYV O61195 662 9 -

Motif 8 width=22
Element Seqn Id St Int Rpt
LPYDLRASFCRLMLHMHVDRDP IP3R_MOUSE 773 162 -
LPYDLRASFCRLMLHMHVDRDP IP3R_RAT 773 162 -
LPYDLRASFCRLMLHMHVDRDP Q14643 759 163 -
LPYDLRASFCRLMLHMHVDRDP Q14660 774 163 -
LPFDLRASFCRLMLHMHVDRDP Q91908 758 162 -
LPFDLRASFCRLMLHMHVDRDP IP3S_HUMAN 770 159 -
LPFDLRASFCRLMLHMHVDRDP IP3S_RAT 770 159 -
LPFDLRASFCHLMLHVHVDRDP Q14573 769 158 -
LPFDLRASFCHLMLHVHVDRDP Q63269 769 158 -
LPFDLRASFCHLMLHVHVDRDP Q14649 769 158 -
MPYELRASFCRLMLHLHVDRDP IP3R_DROME 836 201 -
LAYDLRAAFCRLMLHMHVDCEP O77089 772 166 -
LPYDLRGSFTRLMLHLHVVRGS O61193 830 143 -
LPYDLRGSFTRLMLHLHVVRGS O61194 830 143 -
LPYDLRGSFTRLMLHLHVVRGS O61195 830 143 -

Motif 9 width=26
Element Seqn Id St Int Rpt
FEVVNLARNLIYFGFYNFSDLLRLTK IP3R_MOUSE 864 69 -
FEVVNLARNLIYFGFYNFSDLLRLTK IP3R_RAT 864 69 -
FEVVNLARNLIYFGFYNFSDLLRLTK Q14643 850 69 -
FEVVNLARNLIYFGFYNFSDLLRLTK Q14660 865 69 -
FEVVNLARNLIYFGFYNFSDLLRLTK Q91908 849 69 -
FEVVHLARNLIYFGFYSFSELLRLTR IP3S_HUMAN 862 70 -
FEVVHLARNLIYFGFYSFSELLRLTR IP3S_RAT 862 70 -
FEVVSLAHNLIYFGFYSFSELLRLTR Q14573 861 70 -
FEVVSLAHNLIYFGFYSFSELLRLTR Q63269 861 70 -
FEVVSLAHNLIYFGFYSFSELLRLTR Q14649 861 70 -
FEVVKLARDLIYFGFYSFSDLLRLTK IP3R_DROME 931 73 -
FEVVKLARYLIYFGFYSFNDLLRLTK O77089 865 71 -
YEIVNLAKALAQFNFYSFNDLLQLTQ O61193 927 75 -
YEIVNLAKALAQFNFYSFNDLLQLTQ O61194 927 75 -
YEIVNLAKALAQFNFYSFNDLLQLTQ O61195 927 75 -