SPRINT Home UMBER Home Contents Standard Search Advanced Search Relation Search

==SPRINT==> PRINTS View



  selected as


PR00028

Identifier
POUDOMAIN  [View Relations]  [View Alignment]  
Accession
PR00028
No. of Motifs
5
Creation Date
08-JUN-1993  (UPDATE 28-JUL-1999)
Title
POU domain signature
Database References

PROSITE; PS00035 POU_1; PS00465 POU_2
BLOCKS; BL00035
PFAM; PF00157 pou
INTERPRO; IPR000327
PDB; 1POU; 1OCT
SCOP; 1POU; 1OCT
Literature References
1. MATHIS, J.M., SIMMONS, D.M., HE, X., SWANSON, L.W. AND ROSENFELD, M.G.
Brain-4 - A novel mammalian POU-domain transcription factor exhibiting
restricted brain-specific expression.
EMBO J. 11 2551-2561 (1992).
 
2. JOHNSON, W.A. AND HIRSH, J.
Binding of Drosophila POU-domain protein to a sequence element regulating
gene expression in specific dopaminergic neurons.
NATURE 343 467-470 (1990).
 
3. PETRYNIAK, B., STAUDT, L.M., POSTEMA, C.E., MCCORMACK W.T. AND 
THOMPSON, C.
Characterization of chicken octamer-binding proteins demonstrates that POU
domain-containing homebox transcription factors have been highly conserved
during vertebrate evolution.
PROC.NATL.ACAD.SCI.U.S.A. 87 1099-1103 (1990).
 
4. ASSA-MUNT, N., MORTISHIRE-SMITH, R.J., AURORA, R., HERR, W. AND
WRIGHT, P.E. 
The solution structure of the Oct-1 POU-specific domain reveals a striking
similarity to the bacteriophage lambda repressor DNA-binding domain.
CELL 73 193-205 (1993).
 
5. KLEMM, J.D., ROULD, M.A., AURORA, R., HERR, W. AND PABO, C.O.
Crystal structure of the Oct-1 POU domain bound to an octamer site:
DNA recognition with tethered DNA-binding modules.
CELL 77 21-32 (1994).

Documentation
Many proteins that regulate gene expression contain a 60 amino acid region 
known as the homeodomain. Some of these (e.g., Oct-1, Oct-2 and Pit-1) have
a bipartite DNA-binding region known as the POU domain, which contains the 
homeodomain and a POU-specific (Pit, Oct, Unc) domain [2] - this latter is 
a region of 70-75 amino acids found upstream of the homeobox. Such proteins
bind to specific DNA sequences to cause temporal and spatial regulation of 
the expression of genes, many of which are involved in the regulation of 
neuronal development in the central nervous system of mammals [2]. Some 
other genes are also regulated, including those for immunoglobulin light 
and heavy chains (Oct-2) [3], and trophic hormone genes, such as those for 
prolactin and growth hormone (Pit-1). Both elements of the POU-domain are 
required for high affinity sequence-specific DNA-binding. The domain may 
also be involved in protein-protein interactions [1]. The 3-D structure 
structure of the POU-domain has been determined by multidimensional
NMR [4] and X-ray crystallography to 3.0 A resolution [5].
 
POUDOMAIN is a 5-element fingerprint that provides a signature for the 
POU-specific DNA-binding domain. The fingerprint was derived from an 
initial alignment of 10 sequences: motif 1 encodes residues 16-33 of the
domain and motif 2 encodes residues 42-55 (cf. PROSITE patterns POU_1
(PS00035) and POU_2 (PS00465)). Two iterations on OWL20.0 were required to
reach convergence, at which point a true set comprising 66 sequences was
identified. Four fragments were also found, all of which lack the portions
of sequence bearing the first and last motifs.
 
An update on SPTR37_9f identified a true set of 96 sequences, and 2
partial matches.
Summary Information
  96 codes involving  5 elements
0 codes involving 4 elements
0 codes involving 3 elements
2 codes involving 2 elements
Composite Feature Index
59696969696
400000
300000
200022
12345
True Positives
BR3A_HUMAN    BR3A_MOUSE    BR3B_HUMAN    BR3B_MOUSE    
BR3C_HUMAN BR3C_MOUSE BRN1_HUMAN BRN1_MOUSE
BRN1_RAT BRN3_CHICK BRN4_HUMAN BRN4_MOUSE
CF1A_DROME HM06_CAEEL HM18_CAEEL HMP1_BOVIN
HMP1_HUMAN HMP1_MELGA HMP1_MOUSE HMP1_ONCKE
HMP1_ONCMY HMP1_PIG HMP1_RAT HMP1_SHEEP
IPOU_DROME O13006 O13007 O17487
O18452 O18807 O42276 O57514
O57599 O57602 O60557 O73627
O73628 O73629 O73861 O75757
O77214 OC11_MOUSE OC3A_HUMAN OC3B_HUMAN
OC3N_HUMAN OC3N_MOUSE OC3N_RAT OCT1_CHICK
OCT1_HUMAN OCT1_MOUSE OCT1_XENLA OCT2_HUMAN
OCT2_MOUSE OCT2_PIG OCT3_MOUSE OCT6_HUMAN
OCT6_MOUSE OCT6_RAT P78424 P78425
PDM1_DROME PDM2_DROME PO3A_XENLA PO3B_XENLA
PO61_HUMAN PO61_MOUSE PO61_RAT POU1_BRARE
POU1_DUGJA POU1_XENLA POU2_BRARE POU2_XENLA
POUC_BRARE Q03916 Q03917 Q06416
Q16648 Q28503 Q29076 Q91441
Q91481 Q91485 Q91809 Q91989
Q94551 Q98978 Q99293 SGF3_BOMMO
SK1A_RAT SK1I_RAT SPM1_RAT UN86_CAEEL
ZP12_BRARE ZP23_BRARE ZP47_BRARE ZP50_BRARE
True Positive Partials
Codes involving 2 elements
P70506 Q94432
Sequence Titles
BR3A_HUMAN  BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 3A (BRN-3A) (OCT-T1) (HOMEOBOX/POU DOMAIN PROTEIN RDC-1) - HOMO SAPIENS (HUMAN). 
BR3A_MOUSE BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 3A (BRN-3A) (BRN-3.0) - MUS MUSCULUS (MOUSE).
BR3B_HUMAN BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 3B (BRN-3B) - HOMO SAPIENS (HUMAN).
BR3B_MOUSE BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 3B (BRN-3B) (BRN-3.2) - MUS MUSCULUS (MOUSE).
BR3C_HUMAN BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 3C (BRN-3C) - HOMO SAPIENS (HUMAN).
BR3C_MOUSE BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 3C (BRN-3C) - MUS MUSCULUS (MOUSE).
BRN1_HUMAN BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 1 (BRN-1 PROTEIN) - HOMO SAPIENS (HUMAN).
BRN1_MOUSE BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 1 (BRN-1 PROTEIN) - MUS MUSCULUS (MOUSE).
BRN1_RAT BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 1 (BRN-1 PROTEIN) - RATTUS NORVEGICUS (RAT).
BRN3_CHICK BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 3 (BRN-3) - GALLUS GALLUS (CHICKEN).
BRN4_HUMAN BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 4 - HOMO SAPIENS (HUMAN).
BRN4_MOUSE BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 4 (RHS2 CLASS III POU PROTEIN) - MUS MUSCULUS (MOUSE), AND RATTUS NORVEGICUS (RAT).
CF1A_DROME POU-DOMAIN PROTEIN CF1A (CHORION FACTOR 1A) (CF1-A) (VENTRAL VEINS LACKING PROTEIN) (DRIFTER PROTEIN) - DROSOPHILA MELANOGASTER (FRUIT FLY).
HM06_CAEEL HOMEOBOX PROTEIN CEH-6 - CAENORHABDITIS ELEGANS.
HM18_CAEEL HOMEOBOX PROTEIN CEH-18 - CAENORHABDITIS ELEGANS.
HMP1_BOVIN PITUITARY-SPECIFIC POSITIVE TRANSCRIPTION FACTOR 1 (PIT-1) (GROWTH HORMONE FACTOR 1) (GHF-1) - BOS TAURUS (BOVINE).
HMP1_HUMAN PITUITARY-SPECIFIC POSITIVE TRANSCRIPTION FACTOR 1 (PIT-1) (GROWTH HORMONE FACTOR 1) (GHF-1) - HOMO SAPIENS (HUMAN).
HMP1_MELGA PITUITARY-SPECIFIC POSITIVE TRANSCRIPTION FACTOR 1 (PIT-1) (GROWTH HORMONE FACTOR 1) (GHF-1) - MELEAGRIS GALLOPAVO (COMMON TURKEY).
HMP1_MOUSE PITUITARY-SPECIFIC POSITIVE TRANSCRIPTION FACTOR 1 (PIT-1) (GROWTH HORMONE FACTOR 1) (GHF-1) - MUS MUSCULUS (MOUSE).
HMP1_ONCKE PITUITARY-SPECIFIC POSITIVE TRANSCRIPTION FACTOR 1 (PIT-1) (GROWTH HORMONE FACTOR 1) (GHF-1) - ONCORHYNCHUS KETA (CHUM SALMON).
HMP1_ONCMY PITUITARY-SPECIFIC POSITIVE TRANSCRIPTION FACTOR 1 (PIT-1) (GROWTH HORMONE FACTOR 1) (GHF-1) - ONCORHYNCHUS MYKISS (RAINBOW TROUT) (SALMO GAIRDNERI).
HMP1_PIG PITUITARY-SPECIFIC POSITIVE TRANSCRIPTION FACTOR 1 (PIT-1) (GROWTH HORMONE FACTOR 1) (GHF-1) - SUS SCROFA (PIG).
HMP1_RAT PITUITARY-SPECIFIC POSITIVE TRANSCRIPTION FACTOR 1 (PIT-1) (GROWTH HORMONE FACTOR 1) (GHF-1) - RATTUS NORVEGICUS (RAT).
HMP1_SHEEP PITUITARY-SPECIFIC POSITIVE TRANSCRIPTION FACTOR 1 (PIT-1) (GROWTH HORMONE FACTOR 1) (GHF-1) - OVIS ARIES (SHEEP).
IPOU_DROME INHIBITORY POU PROTEIN (I-POU) (ABNORMAL CHEMOSENSORY JUMP 6 PROTEIN) - DROSOPHILA MELANOGASTER (FRUIT FLY).
O13006 OCT-2 ALPHA TRANSCRIPTION FACTOR - ICTALURUS PUNCTATUS (CHANNEL CATFISH).
O13007 OCT-2 BETA TRANSCRIPTION FACTOR (OCT2 BETA) - ICTALURUS PUNCTATUS (CHANNEL CATFISH).
O17487 APH-1 - ARTEMIA SANFRANCISCANA (BRINE SHRIMP) (ARTEMIA FRANCISCANA).
O18452 CLASS IV POU PROTEIN - HERDMANIA CURVATA.
O18807 POU-DOMAIN TRANSCRIPTIONAL REGULATOR - SUS SCROFA (PIG).
O42276 OCTAMER-BINDING TRANSCRIPTION FACTOR 1 - BRACHYDANIO RERIO (ZEBRAFISH) (ZEBRA DANIO).
O57514 POU DOMAIN PROTEIN ZP-12 (CLASS III POU DOMAIN PROTEIN TAICHI) - BRACHYDANIO RERIO (ZEBRAFISH) (ZEBRA DANIO).
O57599 PITUITARY SPECIFIC TRANSCRIPTION FACTOR - GALLUS GALLUS (CHICKEN).
O57602 OCT1 TRANSCRIPTION FACTOR - ICTALURUS PUNCTATUS (CHANNEL CATFISH).
O60557 TRANSCRIPTION FACTOR POU4F3 - HOMO SAPIENS (HUMAN).
O73627 BRAIN-1 GENE - ANOLIS CAROLINENSIS (GREEN ANOLE) (AMERICAN CHAMELEON).
O73628 BRAIN-2 GENE - ANOLIS CAROLINENSIS (GREEN ANOLE) (AMERICAN CHAMELEON).
O73629 BRAIN-4 GENE - ANOLIS CAROLINENSIS (GREEN ANOLE) (AMERICAN CHAMELEON).
O73861 POU CLASS III TRANSCRIPTION FACTOR - GALLUS GALLUS (CHICKEN).
O75757 PIT-1/GHF-1 - HOMO SAPIENS (HUMAN).
O77214 POU DOMAIN TRANSCRIPTION FACTOR - DROSOPHILA MELANOGASTER (FRUIT FLY).
OC11_MOUSE OCTAMER-BINDING TRANSCRIPTION FACTOR 11 (OCT-11) - MUS MUSCULUS (MOUSE).
OC3A_HUMAN OCTAMER-BINDING TRANSCRIPTION FACTOR 3A (OCT-3A) (OCT-4) - HOMO SAPIENS (HUMAN).
OC3B_HUMAN OCTAMER-BINDING TRANSCRIPTION FACTOR 3B (OCT-3B) - HOMO SAPIENS (HUMAN).
OC3N_HUMAN NERVOUS-SYSTEM SPECIFIC OCTAMER-BINDING TRANSCRIPTION FACTOR N-OCT 3 (BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 2) (BRN-2 PROTEIN) [CONTAINS: N-OCT 5A; N-OCT 5B] - HOMO SAPIENS (HUMAN).
OC3N_MOUSE NERVOUS-SYSTEM SPECIFIC OCTAMER-BINDING TRANSCRIPTION FACTOR N-OCT 3 (BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 2) (BRN-2 PROTEIN) - MUS MUSCULUS (MOUSE).
OC3N_RAT NERVOUS-SYSTEM SPECIFIC OCTAMER-BINDING TRANSCRIPTION FACTOR N-OCT 3 (BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 2) (BRN-2 PROTEIN) - RATTUS NORVEGICUS (RAT).
OCT1_CHICK OCTAMER-BINDING TRANSCRIPTION FACTOR 1 (OTF-1) (NF-A1) - GALLUS GALLUS (CHICKEN).
OCT1_HUMAN OCTAMER-BINDING TRANSCRIPTION FACTOR 1 (OTF-1) (NF-A1) - HOMO SAPIENS (HUMAN).
OCT1_MOUSE OCTAMER-BINDING TRANSCRIPTION FACTOR 1 (OTF-1) (NF-A1) - MUS MUSCULUS (MOUSE).
OCT1_XENLA OCTAMER-BINDING TRANSCRIPTION FACTOR 1 (OTF-1) (NF-A1) (XOCT1) - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
OCT2_HUMAN OCTAMER-BINDING TRANSCRIPTION FACTOR 2 (OTF-2) (LYMPHOID-RESTRICTED IMMUNOGLOBULIN OCTAMER BINDING PROTEIN NF-A2) (OCT-2 FACTOR) - HOMO SAPIENS (HUMAN).
OCT2_MOUSE OCTAMER-BINDING TRANSCRIPTION FACTOR 2 (OTF-2) (LYMPHOID-RESTRICTED IMMUNOGLOBULIN OCTAMER BINDING PROTEIN NF-A2) (OCT-2 FACTOR) - MUS MUSCULUS (MOUSE).
OCT2_PIG OCTAMER-BINDING TRANSCRIPTION FACTOR 2 (OTF-2) (LYMPHOID-RESTRICTED IMMUNOGLOBULIN OCTAMER BINDING PROTEIN NF-A2) (OCT-2 FACTOR) - SUS SCROFA (PIG).
OCT3_MOUSE OCTAMER-BINDING TRANSCRIPTION FACTOR 3 (OCT3) (OCT4) (NF-A3) - MUS MUSCULUS (MOUSE).
OCT6_HUMAN OCTAMER-BINDING TRANSCRIPTION FACTOR 6 (POU-DOMAIN TRANSCRIPTION FACTOR SCIP) - HOMO SAPIENS (HUMAN).
OCT6_MOUSE OCTAMER-BINDING TRANSCRIPTION FACTOR 6 (OCT-6) (POU-DOMAIN TRANSCRIPTION FACTOR SCIP) - MUS MUSCULUS (MOUSE).
OCT6_RAT OCTAMER-BINDING TRANSCRIPTION FACTOR 6 (OCT-6) (POU-DOMAIN TRANSCRIPTION FACTOR SCIP) (TST-1) - RATTUS NORVEGICUS (RAT).
P78424 RETINA-DERIVED POU-DOMAIN FACTOR-1 - HOMO SAPIENS (HUMAN).
P78425 RETINA-DERIVED POU-DOMAIN FACTOR-1 - HOMO SAPIENS (HUMAN).
PDM1_DROME NUBBIN PROTEIN (TWAIN PROTEIN) (POU DOMAIN PROTEIN 1) (PDM-1) (DPOU- 19) (DOCT1) - DROSOPHILA MELANOGASTER (FRUIT FLY).
PDM2_DROME DIDYMOUS PROTEIN (POU DOMAIN PROTEIN 2) (PDM-2) (DPOU-28) (DOCT2) (MITI-MERE) - DROSOPHILA MELANOGASTER (FRUIT FLY).
PO3A_XENLA TRANSCRIPTION FACTOR POU3A (XLPOU3) - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
PO3B_XENLA TRANSCRIPTION FACTOR POU3B (XLPOU3B) - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
PO61_HUMAN POU DOMAIN, CLASS 6, TRANSCRIPTION FACTOR 1 (MPOU HOMEOBOX PROTEIN) (BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 5) (BRN-5 PROTEIN) - HOMO SAPIENS (HUMAN).
PO61_MOUSE POU DOMAIN, CLASS 6, TRANSCRIPTION FACTOR 1 (OCTAMER-BINDING TRANSCRIPTION FACTOR EMB) (TRANSCRIPTION REGULATORY PROTEIN MCP-1) - MUS MUSCULUS (MOUSE).
PO61_RAT POU DOMAIN, CLASS 6, TRANSCRIPTION FACTOR 1 (BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN PROTEIN 5) (BRN-5 PROTEIN) - RATTUS NORVEGICUS (RAT).
POU1_BRARE POU DOMAIN PROTEIN 1 (ZFPOU1) - BRACHYDANIO RERIO (ZEBRAFISH) (ZEBRA DANIO).
POU1_DUGJA POU DOMAIN PROTEIN 1 (DJPOU1) - DUGESIA JAPONICA (PLANARIAN).
POU1_XENLA TRANSCRIPTION FACTOR POU1 (XLPOU1) (HOMEOTIC PROTEIN NRL-22/NRL-34) - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
POU2_BRARE POU DOMAIN PROTEIN 2 - BRACHYDANIO RERIO (ZEBRAFISH) (ZEBRA DANIO).
POU2_XENLA TRANSCRIPTION FACTOR POU2 (XLPOU2) - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
POUC_BRARE POU DOMAIN PROTEIN C (POU[C]) (ZFPOU[C]) - BRACHYDANIO RERIO (ZEBRAFISH) (ZEBRA DANIO).
Q03916 OCTAMER-BINDING TRANSCRIPTION FACTOR 60 (OCT-60) - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
Q03917 OCTAMER-BINDING TRANSCRIPTION FACTOR 91 (OCT-91) - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
Q06416 OCTAMER-BINDING TRANSCRIPTION FACTOR 3C (OCT-3C) - HOMO SAPIENS (HUMAN).
Q16648 OCT-2 PROTEIN - HOMO SAPIENS (HUMAN).
Q28503 PIT-1/GHF-1 - MACACA MULATTA (RHESUS MACAQUE).
Q29076 OCTAMER BINDING PROTEIN 1 - SUS SCROFA (PIG).
Q91441 PITUITARY TRANSCRIPTION FACTOR - SPARUS AURATA (GILTHEAD SEA BREAM).
Q91481 PITUITARY SPECIFIC TRANSCRIPTION FACTOR PIT-1 - SALMO SALAR (ATLANTIC SALMON).
Q91485 PITUITARY SPECIFIC TRANSCRIPTION FACTOR - SALMO SALAR (ATLANTIC SALMON).
Q91809 MATERNAL TRANSCRIPTION FACTOR - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
Q91989 POU-DOMAIN PROTEIN - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
Q94551 TRANSCRIPTION FACTOR - DUGESIA TIGRINA (PLANARIAN).
Q98978 PIT-1 TRANSCRIPTION FACTOR - ONCORHYNCHUS TSCHAWYTSCHA (CHINOOK SALMON) (KING SALMON).
Q99293 OCTAMER-BINDING TRANSCRIPTION FACTOR 25 (OCT-25) - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
SGF3_BOMMO SILK GLAND FACTOR 3 (POU DOMAIN PROTEIN M1) - BOMBYX MORI (SILK MOTH).
SK1A_RAT TRANSCRIPTION FACTOR SKN-1A - RATTUS NORVEGICUS (RAT).
SK1I_RAT TRANSCRIPTION FACTOR SKN-1I - RATTUS NORVEGICUS (RAT).
SPM1_RAT SPERM 1 POU-DOMAIN TRANSCRIPTION FACTOR (SPRM-1) - RATTUS NORVEGICUS (RAT).
UN86_CAEEL TRANSCRIPTION FACTOR UNC-86 - CAENORHABDITIS ELEGANS.
ZP12_BRARE POU DOMAIN PROTEIN ZP-12 (CLASS III POU DOMAIN PROTEIN TAICHI) - BRACHYDANIO RERIO (ZEBRAFISH) (ZEBRA DANIO).
ZP23_BRARE POU DOMAIN PROTEIN ZP-23 - BRACHYDANIO RERIO (ZEBRAFISH) (ZEBRA DANIO).
ZP47_BRARE POU DOMAIN PROTEIN ZP-47 - BRACHYDANIO RERIO (ZEBRAFISH) (ZEBRA DANIO).
ZP50_BRARE POU DOMAIN PROTEIN ZP-50 - BRACHYDANIO RERIO (ZEBRAFISH) (ZEBRA DANIO).

P70506 GHF-1 PROTEIN - RATTUS NORVEGICUS (RAT).
Q94432 COS2.2 - CIONA INTESTINALIS.
Scan History
OWL20_0    2  100  NSINGLE    
OWL26_0 1 250 NSINGLE
SPTR37_9f 3 120 NSINGLE
Initial Motifs
Motif 1  width=18
Element Seqn Id St Int Rpt
RIKLGYTQTNVGEALAAV HMP1_RAT 169 169 -
RIKLGYTQADVGVALGTL HM06_CAEEL 25 25 -
RIKLGFTQADVGLALGTL CF1A_DROME 270 270 -
RIKLGFTQADVGLALGTL BRN1_HUMAN 2 2 -
RIKLGFTQADVGLALGTL HMO6_MOUSE 264 264 -
RIKLGVTQADVGSALANL BRN3_RAT 2 2 -
RIKLGFTQGDVGLAMGKL HMO1_CHICK 293 293 -
RIKLGFTQADVGLALGTL BRN2_HUMAN 2 2 -
RIKLGVTQADVGKALAHL UN86_CAEEL 284 284 -
RIKLGVTQADVGKALANL IPOU_DROME 214 214 -

Motif 2 width=14
Element Seqn Id St Int Rpt
SQSTICRFESLTLS BRN3_RAT 28 8 -
SQTTISRFEALNLS HMO1_CHICK 316 5 -
SQTTICRFEALQLS HMO6_MOUSE 287 5 -
SQTTICRFEALQLS BRN2_HUMAN 25 5 -
SQTTICRFEALQLS BRN1_HUMAN 25 5 -
SQTTICRFEALQLS CF1A_DROME 293 5 -
SQTTICRFEALQLS HM06_CAEEL 48 5 -
SQTTICRFENLQLS HMP1_RAT 192 5 -
SQSTICRFESLTLS IPOU_DROME 240 8 -
SQSTICRFESLTLS UN86_CAEEL 310 8 -

Motif 3 width=16
Element Seqn Id St Int Rpt
NMCKLKPLLQKWLEEA CF1A_DROME 309 2 -
NMCKLKPLLNKWLEEA BRN1_HUMAN 41 2 -
NMVALKPILHSWLEKA UN86_CAEEL 326 2 -
NMCKLKPLLNKWLEEA BRN2_HUMAN 41 2 -
NMIALKPILQAWLEEA BRN3_RAT 44 2 -
NMCKLKPLLNKWLEET HMO6_MOUSE 303 2 -
NMCKLKPLLEKWLNDA HMO1_CHICK 332 2 -
NMIALKPILQAWLEEA IPOU_DROME 256 2 -
NACKLKAILSKWLEEA HMP1_RAT 208 2 -
NMCKLKPLLFKWLEEA HM06_CAEEL 64 2 -

Motif 4 width=21
Element Seqn Id St Int Rpt
RKRKKRTSIEVGVKGALESHF HMO6_MOUSE 336 17 -
RRRKKRTSIETNIRVALEKSF HMO1_CHICK 374 26 -
RKRKKRTSIEVSVKGALESHF BRN1_HUMAN 74 17 -
RKRKKRTSIEVSVKGALEQHF CF1A_DROME 342 17 -
RKRKKRTSIEVNVKSRLEFHF HM06_CAEEL 99 19 -
RKRKRRTTISIAAKDALERHF HMP1_RAT 239 15 -
AGEKKRTSIAAPEKRSLEAYF IPOU_DROME 290 18 -
DKKRKRTSIAAPEKRELEQFF UN86_CAEEL 362 20 -
EKKRKRTSIAAPEKRSLEAYF BRN3_RAT 77 17 -
RKRKKRTSIEVSVKGALESHF BRN2_HUMAN 74 17 -

Motif 5 width=16
Element Seqn Id St Int Rpt
AEKLDLKKNVVRVWFC BRN3_RAT 112 14 -
ADSLQLEKEVVRVWFC BRN2_HUMAN 109 14 -
ADRLDLKKNVVRVWFC UN86_CAEEL 397 14 -
AEKLDLKKNVVRVWFC IPOU_DROME 325 14 -
AEELNLEKEVVRVWFC HMP1_RAT 274 14 -
AMELQLEKEVVRVWFC HM06_CAEEL 134 14 -
ADSLQLEKEVVRVWFC CF1A_DROME 377 14 -
ADSLQLEKEVVRVWFC BRN1_HUMAN 109 14 -
ADQLNMEKEVIRVWFC HMO1_CHICK 409 14 -
ADSLQLEKEVVRVWFC HMO6_MOUSE 371 14 -
Final Motifs
Motif 1  width=18
Element Seqn Id St Int Rpt
RIKLGFTQADVGLALGTL BRN1_MOUSE 328 328 -
RIKLGFTQADVGLALGTL BRN1_RAT 330 330 -
RIKLGFTQADVGLALGTL O73627 287 287 -
RIKLGFTQADVGLALGTL O73628 283 283 -
RIKLGFTQADVGLALGTL OC3N_HUMAN 281 281 -
RIKLGFTQADVGLALGTL OC3N_MOUSE 283 283 -
RIKLGFTQADVGLALGTL OC3N_RAT 283 283 -
RIKLGFTQADVGLALGTL PO3B_XENLA 223 223 -
RIKLGFTQADVGLALGTL ZP47_BRARE 219 219 -
RIKLGFTQADVGLALGTL O57514 260 260 -
RIKLGFTQADVGLALGTL ZP23_BRARE 257 257 -
RIKLGFTQADVGLALGTL ZP12_BRARE 260 260 -
RIKLGFTQADVGLALGTL CF1A_DROME 270 270 -
RIKLGFTQADVGLALGTL SGF3_BOMMO 168 168 -
RIKLGFTQADVGLALGTL O17487 187 187 -
RIKLGFTQADVGLALGTL BRN4_HUMAN 205 205 -
RIKLGFTQADVGLALGTL POU2_XENLA 62 62 -
RIKLGFTQADVGLALGTL O73629 194 194 -
RIKLGFTQADVGLALGTL BRN4_MOUSE 205 205 -
RIKLGFTQADVGLALGTL OCT6_HUMAN 263 263 -
RIKLGFTQADVGLALGTL OCT6_MOUSE 264 264 -
RIKLGFTQADVGLALGTL OCT6_RAT 266 266 -
RIKLGFTQADVGLALGTL PO3A_XENLA 220 220 -
RIKLGFTQADVGLALGTL O73861 210 210 -
RIKLGFTQADVGLALGTL POU1_XENLA 194 194 -
RIKLGFKQADVGLALGTL POU1_BRARE 257 257 -
RIKLGFTQADVGLALGTL ZP50_BRARE 206 206 -
RIKLGYTQADVGVALGTL HM06_CAEEL 25 25 -
RIKLGYTQADVGLALGTL POU1_DUGJA 278 278 -
RIKLGYTQADVGLALGTL Q94551 279 279 -
RIKLGFTQGDVGLAMGKL O42276 195 195 -
RIKLGFTQGDVGLAMGKL SK1A_RAT 195 195 -
RIKLGFTQGDVGLAMGKL SK1I_RAT 113 113 -
RIKLGFTQGDVGLAMGKL O13007 216 216 -
RIKLGFTQGDVGLAMGKL O57602 221 221 -
RIKLGFTQGDVGLAMGKL OCT2_HUMAN 213 213 -
RIKLGFTQGDVGLAMGKL OCT2_MOUSE 197 197 -
RIKLGFTQGDVGLAMGKL OCT2_PIG 214 214 -
RIKLGFTQGDVGLAMGKL Q16648 214 214 -
RIKLGFTQGDVGLAMGKL PDM1_DROME 440 440 -
RIKLGFTQGDVGLAMGKL OCT1_MOUSE 300 300 -
RIKLGFTQGDVGLAMGKL O13006 216 216 -
RIKLGFTQGDVGLAMGKL OCT1_CHICK 293 293 -
RIKLGFTQGDVGLAMGKL OCT1_HUMAN 299 299 -
RIKLGFTQGDVGLAMGKL OCT1_XENLA 313 313 -
RIKLGFTQGDVGLAMGKL Q29076 299 299 -
RIKLGFTQGDVGLAMGKL Q91809 313 313 -
RIKLGFTQADVGLALGTL BRN1_HUMAN 2 2 -
RIKLGYTQTNVGEALAAV HMP1_MOUSE 143 143 -
RIKLGYTQTNVGEALAAV HMP1_BOVIN 143 143 -
RIKLGYTQTNVGEALAAV Q28503 169 169 -
RIKLGYTQTNVGEALAAV O75757 169 169 -
RIKLGYTQTNVGEALAAV HMP1_RAT 169 169 -
RIKLGYTQTNVGEALAAV HMP1_HUMAN 143 143 -
RIKLGFTQGDVGLAMGKL OC11_MOUSE 195 195 -
RIKLGYTQTNVGEALAAV O57599 178 178 -
RIKLGYTQTNVGEALAAV HMP1_SHEEP 143 143 -
RIKLGYTQTNVGEALAAV O18807 143 143 -
RITLGFTQADVGLALGNL POU2_BRARE 268 268 -
RIKLGYTQTNVGEALAAV HMP1_MELGA 221 221 -
RIKLGFTQGDVGLAMGKL PDM2_DROME 305 305 -
RIKLGYTQTNVGEALAAV HMP1_ONCKE 207 207 -
RIKLGYTQTNVGEALAAV HMP1_ONCMY 211 211 -
RIKLGYTQTNVGEALAAV Q98978 211 211 -
RIKLGYTQTNVGEALAAV HMP1_PIG 143 143 -
RIKLGYTQTNVGEALAAV Q91441 213 213 -
RITLGYTQADVGLTLGVL OC3A_HUMAN 157 157 -
RITLGYTQADVGLTLGVL OC3B_HUMAN 62 62 -
RIKLGYTQTNVGEALAAV Q91481 211 211 -
RIKLGYTQTNVGEALAAV Q91485 211 211 -
RITLGYTQADVGLTLGVL OCT3_MOUSE 150 150 -
RITMGYTQADVGYALGVL Q03917 237 237 -
RIKLGVTQADVGSALANL BR3A_HUMAN 283 283 -
RIKLGVTQADVGSALANL BR3A_MOUSE 281 281 -
RIKLGVTQADVGSALANL BR3B_HUMAN 270 270 -
RIKLGVTQADVGSALANL BR3B_MOUSE 271 271 -
RIKLGVTQADVGKALANL O77214 241 241 -
RITLGYTQADVGLILGVL Q06416 157 157 -
RIKLGVTQADVGSALANL BRN3_CHICK 201 201 -
RIKLGVTQADVGKALANL IPOU_DROME 214 214 -
RVSLGYTQADVGYALGVL Q99293 246 246 -
RIKLGVTQADVGAALANL BR3C_HUMAN 198 198 -
RIKLGVTQADVGAALANL BR3C_MOUSE 198 198 -
RIKLGVTQADVGAALANL O60557 198 198 -
RVALGYTQGDIGHALGIL Q03916 221 221 -
RVALGYTQGDIGHALGIL Q91989 221 221 -
RIKLGVTQADVGKALAHL UN86_CAEEL 284 284 -
RIKLGVTQCNVGQALAKL O18452 280 280 -
RIKFGFTQGDVGVALGKR HM18_CAEEL 309 309 -
RLSLGLTQTQVGQALTAT PO61_HUMAN 158 158 -
RLSLGLTQTQVGQALTAT PO61_RAT 158 158 -
RLSLGLTQTQVGQALTAT PO61_MOUSE 158 158 -
RMTLGYTQADVGFAVGAM SPM1_RAT 132 132 -
RLSLGLTQTQVGQALTAT POUC_BRARE 467 467 -
RLSLGLTQTQVGQALSAT P78425 488 488 -
RLSLGLTQTQVGQALSAT P78424 488 488 -

Motif 2 width=14
Element Seqn Id St Int Rpt
SQSAICRHTILRSH P78424 511 5 -
SQTTICRFEALQLS BRN1_MOUSE 351 5 -
SQTTICRFEALQLS BRN1_RAT 353 5 -
SQTTICRFEALQLS O73627 310 5 -
SQTTICRFEALQLS O73628 306 5 -
SQTTICRFEALQLS OC3N_HUMAN 304 5 -
SQTTICRFEALQLS OC3N_MOUSE 306 5 -
SQTTICRFEALQLS OC3N_RAT 306 5 -
SQTTICRFEALQLS PO3B_XENLA 246 5 -
SQTTICRFEALQLS ZP47_BRARE 242 5 -
SQTTICRFEALQLS O57514 283 5 -
SQTTICRFEALQLS ZP23_BRARE 280 5 -
SQTTICRFEALQLS ZP12_BRARE 283 5 -
SQTTICRFEALQLS CF1A_DROME 293 5 -
SQTTICRFEALQLS SGF3_BOMMO 191 5 -
SQTTICRFEALQLS O17487 210 5 -
SQTTICRFEALQLS BRN4_HUMAN 228 5 -
SQTTICRFEALQLS POU2_XENLA 85 5 -
SQTTICRFEALQLS O73629 217 5 -
SQTTICRFEALQLS BRN4_MOUSE 228 5 -
SQTTICRFEALQLS OCT6_HUMAN 286 5 -
SQTTICRFEALQLS OCT6_MOUSE 287 5 -
SQTTICRFEALQLS OCT6_RAT 289 5 -
SQTTICRFEALQLS PO3A_XENLA 243 5 -
SQTTICRFEALQLS BRN1_HUMAN 25 5 -
SQTTICRFEALQLS O73861 233 5 -
SQTTICRFEALQLS POU1_XENLA 217 5 -
SQTTICRFEALQLS POU1_BRARE 280 5 -
SQTTICRFEALQLS ZP50_BRARE 229 5 -
SQTTICRFEALQLS HM06_CAEEL 48 5 -
SQTTICRFEALQLS POU1_DUGJA 301 5 -
SQTTICRFEALQLS Q94551 302 5 -
SQTTISRFEALNLS O42276 218 5 -
SQTTISRFEALNLS SK1A_RAT 218 5 -
SQTTISRFEALNLS SK1I_RAT 136 5 -
SQTTISRFEALNLS O13007 239 5 -
SQTTISRFEALNLS O57602 244 5 -
SQTTISRFEALNLS OCT2_HUMAN 236 5 -
SQTTISRFEALNLS OCT2_MOUSE 220 5 -
SQTTISRFEALNLS OCT2_PIG 237 5 -
SQTTISRFEALNLS Q16648 237 5 -
SQTTISRFEALNLS PDM1_DROME 463 5 -
SQTTISRFEALNLS OCT1_MOUSE 323 5 -
SQTTISRFEALNLS O13006 239 5 -
SQTTISRFEALNLS OCT1_CHICK 316 5 -
SQTTISRFEALNLS OCT1_HUMAN 322 5 -
SQTTISRFEALNLS OCT1_XENLA 336 5 -
SQTTISRFEALNLS Q29076 322 5 -
SQTTISRFEALNLS Q91809 336 5 -
SQTTICRFENLQLS HMP1_MOUSE 166 5 -
SQTTICRFENLQLS HMP1_BOVIN 166 5 -
SQTTICRFENLQLS Q28503 192 5 -
SQTTICRFENLQLS O75757 192 5 -
SQTTICRFENLQLS HMP1_RAT 192 5 -
SQTTICRFENLQLS HMP1_HUMAN 166 5 -
SQTTISRFEALNLS OC11_MOUSE 218 5 -
SQTTICRFENLQLS O57599 201 5 -
SQTTICRFENLQLS HMP1_SHEEP 166 5 -
SQTTICRFENLQLS O18807 166 5 -
SQTTICRFEALQLS POU2_BRARE 291 5 -
SQTTICRFENSQLS HMP1_MELGA 244 5 -
SQTTISRFEALNLS PDM2_DROME 328 5 -
SQTTICRFENLQLS HMP1_ONCKE 230 5 -
SQTTICRFENLQLS HMP1_ONCMY 234 5 -
SQTTICRFENLQLS Q98978 234 5 -
SQTTICRFENLQLS HMP1_PIG 166 5 -
SQTTICRFENLQLS Q91441 236 5 -
SQTTICRFEALQLS OC3A_HUMAN 180 5 -
SQTTICRFEALQLS OC3B_HUMAN 85 5 -
SQTTICRFENLQLS Q91481 234 5 -
SQTTICRFENLQLS Q91485 234 5 -
SQTTICRFEALQLS OCT3_MOUSE 173 5 -
SQTTICRFESLQLS Q03917 260 5 -
SQSTICRFESLTLS BR3A_HUMAN 309 8 -
SQSTICRFESLTLS BR3A_MOUSE 307 8 -
SQSTICRFESLTLS BR3B_HUMAN 296 8 -
SQSTICRFESLTLS BR3B_MOUSE 297 8 -
SQSTICRFESLTLS O77214 267 8 -
SQKTICRFEALQLS Q06416 180 5 -
SQSTICRFESLTLS BRN3_CHICK 227 8 -
SQSTICRFESLTLS IPOU_DROME 240 8 -
SQTTICRFESLQLS Q99293 269 5 -
SQSTICRFESLTLS BR3C_HUMAN 224 8 -
SQSTICRFESLTLS BR3C_MOUSE 224 8 -
SQSTICRFESLTLS O60557 224 8 -
SQTTICRFESLQLT Q03916 244 5 -
SQTTICRFESLQLT Q91989 244 5 -
SQSTICRFESLTLS UN86_CAEEL 310 8 -
SQSTICRFESLTLS O18452 306 8 -
SQTTISRFEALNLS HM18_CAEEL 332 5 -
SQSAICRFEKLDIT PO61_HUMAN 181 5 -
SQSAICRFEKLDIT PO61_RAT 181 5 -
SQSAICRFEKLDIT PO61_MOUSE 181 5 -
SQTTICRFEAQQLS SPM1_RAT 155 5 -
SQSAICRFEKLDIT POUC_BRARE 490 5 -
SQSAICRFEKLDIT P78425 511 5 -

Motif 3 width=16
Element Seqn Id St Int Rpt
NACKLKAILSKWLEEA HMP1_MOUSE 182 2 -
NMCKLKPLLNKWLEEA BRN1_HUMAN 41 2 -
NMCKLKPLLNKWLEEA BRN1_MOUSE 367 2 -
NMCKLKPLLNKWLEEA BRN1_RAT 369 2 -
NMCKLKPLLNKWLEEA O73627 326 2 -
NMCKLKPLLNKWLEEA O73628 322 2 -
NMCKLKPLLNKWLEEA OC3N_HUMAN 320 2 -
NMCKLKPLLNKWLEEA OC3N_MOUSE 322 2 -
NMCKLKPLLNKWLEEA OC3N_RAT 322 2 -
NMCKLKPLLNKWLEEA PO3B_XENLA 262 2 -
NMCKLKPLLNKWLEEA ZP47_BRARE 258 2 -
NMCKLKPLLNKWLEEA O57514 299 2 -
NMCKLKPLLNKWLEEA ZP23_BRARE 296 2 -
NMCKLKPLLNKWLEEA ZP12_BRARE 299 2 -
NMCKLKPLLQKWLEEA CF1A_DROME 309 2 -
NMCKLKPLLQKWLEEA SGF3_BOMMO 207 2 -
NMCKLKPLLQKWLEEA O17487 226 2 -
NMCKLKPLLNKWLEEA BRN4_HUMAN 244 2 -
NMCKLKPLLNKWLEEA POU2_XENLA 101 2 -
NMCKLKPLLNKWLEEA O73629 233 2 -
NMCKLKPLLNKWLEEA BRN4_MOUSE 244 2 -
NMCKLKPLLNKWLEET OCT6_HUMAN 302 2 -
NMCKLKPLLNKWLEET OCT6_MOUSE 303 2 -
NMCKLKPLLNKWLEET OCT6_RAT 305 2 -
NMCKLKPLLNKWLEEA PO3A_XENLA 259 2 -
NMCKLKPLLNKWLEET O73861 249 2 -
NMCKLKPLLNKWLEET POU1_XENLA 233 2 -
NMCKLKPLLNKWLEEA POU1_BRARE 296 2 -
NMCKLKPLLNKWLEET ZP50_BRARE 245 2 -
NMCKLKPLLFKWLEEA HM06_CAEEL 64 2 -
NMCKLRPLLQKWLHEA POU1_DUGJA 317 2 -
NMCKLRPLLQKWLHEA Q94551 318 2 -
NMCKLKPLLEKWLTDA O42276 234 2 -
NMCKLKPLLEKWLNDA SK1A_RAT 234 2 -
NMCKLKPLLEKWLNDA SK1I_RAT 152 2 -
NMCKLKPLLEKWLTDA O13007 255 2 -
NMCKLKPLLEKWLNDA O57602 260 2 -
NMCKLKPLLEKWLNDA OCT2_HUMAN 252 2 -
NMCKLKPLLEKWLNDA OCT2_MOUSE 236 2 -
NMCKLKPLLEKWLNDA OCT2_PIG 253 2 -
NMCKLKPLLEKWLNDA Q16648 253 2 -
NMCKLKPLLQKWLDDA PDM1_DROME 479 2 -
NMCKLKPLLEKWLNDA OCT1_MOUSE 339 2 -
NMCKLKPLLEKWLTDA O13006 255 2 -
NMCKLKPLLEKWLNDA OCT1_CHICK 332 2 -
NMCKLKPLLEKWLNDA OCT1_HUMAN 338 2 -
NMCKLKPLLEKWLNDA OCT1_XENLA 352 2 -
NMCKLKPLLEKWLNDA Q29076 338 2 -
NMCKLKPLLEKWLNDA Q91809 352 2 -
NACKLKAILSKWLEEA HMP1_BOVIN 182 2 -
NACKLKAILSKWLEEA Q28503 208 2 -
NACKLKAILSKWLEEA O75757 208 2 -
NACKLKAILSKWLEEA HMP1_RAT 208 2 -
NACKLKAILSKWLEEA HMP1_HUMAN 182 2 -
NMCKLKPLLEKWLNDP OC11_MOUSE 234 2 -
NACKLKSILSKWLEEA O57599 217 2 -
NACKLKAILFKWLEEA HMP1_SHEEP 182 2 -
NACKLKAILSKWLEEA O18807 182 2 -
NMCKLKPLLQRWLNEA POU2_BRARE 307 2 -
NACKLKSILSKWLEEA HMP1_MELGA 260 2 -
NMCKLKPLLQKWLEDA PDM2_DROME 344 2 -
NACTLKAILAKWLDEA HMP1_ONCKE 246 2 -
NACTLKAILAKWLDEA HMP1_ONCMY 250 2 -
NACTLKAILAKWLDEA Q98978 250 2 -
NRCKLKAILSKWLEVA HMP1_PIG 182 2 -
NACTLKAILAKWLDEA Q91441 252 2 -
NMCKLRPLLQKWVEEA OC3A_HUMAN 196 2 -
NMCKLRPLLQKWVEEA OC3B_HUMAN 101 2 -
NACTLKTILAKWLDET Q91481 250 2 -
NACTLKTILAKWLDET Q91485 250 2 -
NMCKLRPLLEKWVEEA OCT3_MOUSE 189 2 -
NMCKLKPLLRSWLHEV Q03917 276 2 -
NMIALKPILQAWLEEA BR3A_HUMAN 325 2 -
NMIALKPILQAWLEEA BR3A_MOUSE 323 2 -
NMIALKPILQAWLEEA BR3B_HUMAN 312 2 -
NMIALKPILQAWLEEA BR3B_MOUSE 313 2 -
NMIALKPILQAWLEEA O77214 283 2 -
NICKLRPLLQKWVEEA Q06416 196 2 -
NMVALKPILEAWLEEA BRN3_CHICK 243 2 -
NMIALKPILQAWLEEA IPOU_DROME 256 2 -
NMCQLKPFLERWVVEA Q99293 285 2 -
NMIALKPVLQAWLEEA BR3C_HUMAN 240 2 -
NMIALKPVLQAWLEEA BR3C_MOUSE 240 2 -
NMIALKPVLQAWLEEA O60557 240 2 -
NMCKLKPLLEQWLGEA Q03916 260 2 -
NMCKLKPLLEQWLGEA Q91989 260 2 -
NMVALKPILHSWLEKA UN86_CAEEL 326 2 -
NMVALKPILMTWLEQA O18452 322 2 -
NMCKLRPLLKEWLADV HM18_CAEEL 348 2 -
SAQKLKPVLEKWLNEA PO61_HUMAN 197 2 -
SAQKLKPVLEKWLNEA PO61_RAT 197 2 -
SAQKLKPVLEKWLMEA PO61_MOUSE 197 2 -
NMWKLRPLLKMWLEEV SPM1_RAT 171 2 -
SAQKLKPVLERWLAEA POUC_BRARE 506 2 -
SAQKIKPVLERWMAEA P78425 527 2 -
SAQKIKPVLERWMAEA P78424 563 38 -

Motif 4 width=21
Element Seqn Id St Int Rpt
RKRKKRTSIEVSVKGALESHF BRN1_HUMAN 74 17 -
RKRKKRTSIEVSVKGALESHF BRN1_MOUSE 400 17 -
RKRKKRTSIEVSVKGALESHF BRN1_RAT 402 17 -
RKRKKRTSIEVSVKGALESHF O73627 359 17 -
RKRKKRTSIEVSVKGALESHF O73628 355 17 -
RKRKKRTSIEVSVKGALESHF OC3N_HUMAN 353 17 -
RKRKKRTSIEVSVKGALESHF OC3N_MOUSE 355 17 -
RKRKKRTSIEVSVKGALESHF OC3N_RAT 355 17 -
RKRKKRTSIEVSVKGALESHF PO3B_XENLA 295 17 -
RKRKKRTSIEVSVKGALESHF ZP47_BRARE 291 17 -
RKRKKRTSIEVSVKGALESHF O57514 332 17 -
RKRKKRTSIEVSVKGALESHF ZP23_BRARE 329 17 -
RKRKKRTSIEVSVKGALESHF ZP12_BRARE 332 17 -
RKRKKRTSIEVSVKGALEQHF CF1A_DROME 342 17 -
RKRKKRTSIEVSVKGALEQHF SGF3_BOMMO 240 17 -
RKRKKRTSIEVSVKGALEQHF O17487 259 17 -
RKRKKRTSIEVSVKGVLETHF BRN4_HUMAN 277 17 -
RKRKKRTSIEVSVKGVLETHF POU2_XENLA 134 17 -
RKRKKRTSIEVSVKGVLETHF O73629 266 17 -
RKRKKRTSIEVSVKGVLETHF BRN4_MOUSE 277 17 -
RKRKKRTSIEVGVKGALESHF OCT6_HUMAN 335 17 -
RKRKKRTSIEVGVKGALESHF OCT6_MOUSE 336 17 -
RKRKKRTSIEVGVKGALESHF OCT6_RAT 338 17 -
RKRKKRTSIEVSVKGALESHF PO3A_XENLA 292 17 -
RKRKKRTSIEVGVKGALENHF O73861 282 17 -
RKRKKRTSIEVGVKGALENHF POU1_XENLA 266 17 -
RKRKKRTSIEVSVKGALESHF POU1_BRARE 329 17 -
RKRKKRTSIEVGVKGALENHF ZP50_BRARE 278 17 -
RKRKKRTSIEVNVKSRLEFHF HM06_CAEEL 99 19 -
RKRKKRTSIEANVKSILESSF POU1_DUGJA 350 17 -
RKRKKRTSIEANVKSILESSF Q94551 351 17 -
RRRKKRTSIETSIRIALERSF O42276 274 24 -
RKRKKRTSIETNIRLTLEKRF SK1A_RAT 273 23 -
RKRKKRTSIETNIRLTLEKRF SK1I_RAT 191 23 -
RRRKKRTSIETNVRVALERSF O13007 298 27 -
RRRKKRTSIDTNIRIALEKSF O57602 300 24 -
RRRKKRTSIETNVRFALEKSF OCT2_HUMAN 295 27 -
RRRKKRTSIETNVRFALEKSF OCT2_MOUSE 279 27 -
RRRKKRTSIETNVRFALEKSF OCT2_PIG 296 27 -
RRRKKRTSIETNVRFALEKSF Q16648 296 27 -
RRRKKRTSIETTIRGALEKAF PDM1_DROME 522 27 -
RRRKKRTSIETNIRVALEKSF OCT1_MOUSE 381 26 -
RRRKKRTSIETNVRVALERTF O13006 298 27 -
RRRKKRTSIETNIRVALEKSF OCT1_CHICK 374 26 -
RRRKKRTSIETNIRVALEKSF OCT1_HUMAN 378 24 -
RRRKKRTSIETNIRVALEKSF OCT1_XENLA 396 28 -
RRRKKRTSIETNIRVALEKSF Q29076 380 26 -
RRRKKRTSIETNIRVALEKSF Q91809 394 26 -
RKRKRRTTISVAAKDALERHF HMP1_MOUSE 213 15 -
RKRKRRTTISIAAKDALERHF HMP1_BOVIN 213 15 -
RKRKRRTTISIAAKDALERHF Q28503 239 15 -
RKRKRRTTISIAAKDALERHF O75757 239 15 -
RKRKRRTTISIAAKDALERHF HMP1_RAT 239 15 -
RKRKRRTTISIAAKDALERHF HMP1_HUMAN 213 15 -
RKRKKRTSIETNIRLTLEKRF OC11_MOUSE 273 23 -
RKRKRRTTISISAKEALERHF O57599 248 15 -
RKRKRRTTISIAAKDALERHF HMP1_SHEEP 213 15 -
RKRKRRTTISIAAKDALERHF O18807 213 15 -
RKRKRRTSLEGTVRSALESYF POU2_BRARE 342 19 -
RKRKRRTTISIAAKEALERHF HMP1_MELGA 291 15 -
RRRKKRTSIETTVRTTLEKAF PDM2_DROME 390 30 -
RKRKRRTTISLGAKEALERSF HMP1_ONCKE 277 15 -
RKRKRRTTISLGAKEALERSF HMP1_ONCMY 281 15 -
RKRKRRTTISLGAKEALERSF Q98978 281 15 -
RKRKRRTTISIAAKDALERHF HMP1_PIG 213 15 -
RKRKRRTTISLGAKEALERSF Q91441 283 15 -
ARKRKRTSIENRVRGNLENLF OC3A_HUMAN 229 17 -
ARKRKRTSIENRVRGNLENLF OC3B_HUMAN 134 17 -
RKRKRRTTISLGAKEALERSF Q91481 281 15 -
RKRKRRTTISRGAKEALERSF Q91485 281 15 -
ARKRKRTSIENRVRWSLETMF OCT3_MOUSE 222 17 -
QKRKHRTSIENNVKCTLENYF Q03917 311 19 -
EKKRKRTSIAAPEKRSLEAYF BR3A_HUMAN 358 17 -
EKKRKRTSIAAPEKRSLEAYF BR3A_MOUSE 356 17 -
EKKRKRTSIAAPEKRSLEAYF BR3B_HUMAN 345 17 -
EKKRKRTSIAAPEKRSLEAYF BR3B_MOUSE 346 17 -
EKKRKRTSIAAPEKRSLEAYF O77214 319 20 -
ARKRKRTSIENRVRGNLENLF Q06416 229 17 -
DKKRKRTSIAAPEKRSLEAYF BRN3_CHICK 276 17 -
AGEKKRTSIAAPEKRSLEAYF IPOU_DROME 290 18 -
RKRKRRTNIENIVKGTLESYF Q99293 320 19 -
ERKRKRTSIAAPEKRSLEAYF BR3C_HUMAN 273 17 -
ERKRKRTSIAAPEKRSLEAYF BR3C_MOUSE 273 17 -
ERKRKRTSIAAPEKRSLEAYF O60557 273 17 -
RKRKMRTCFDTVLKGQLEGHF Q03916 295 19 -
RKRKMRTCFDTVLKGQLEGHF Q91989 295 19 -
DKKRKRTSIAAPEKRELEQFF UN86_CAEEL 362 20 -
EKKRKRTSIAAPEKRSLEAYF O18452 352 14 -
KRRRKRTNLDMNQRNALDTFF HM18_CAEEL 420 56 -
KKRKRRTSFTPQAIEALNAYF PO61_HUMAN 233 20 -
KKRKRRTSFTPQAIEALNAYF PO61_RAT 233 20 -
KKRKRRTSFTPQAIEALNAYF PO61_MOUSE 233 20 -
ARKRRRASRERRIGSNLEKLF SPM1_RAT 204 17 -
KKRKRRTSFTPQAIEVLNTYF POUC_BRARE 542 20 -
KKRKRRTSFTPQALEILNAHF P78425 563 20 -
KKRKRRTSFTPQALEILNAHF P78424 599 20 -

Motif 5 width=16
Element Seqn Id St Int Rpt
ADSLQLEKEVVRVWFC BRN1_HUMAN 109 14 -
ADSLQLEKEVVRVWFC BRN1_MOUSE 435 14 -
ADSLQLEKEVVRVWFC BRN1_RAT 437 14 -
ADSLQLEKEVVRVWFC O73627 394 14 -
ADSLQLEKEVVRVWFC O73628 390 14 -
ADSLQLEKEVVRVWFC OC3N_HUMAN 388 14 -
ADSLQLEKEVVRVWFC OC3N_MOUSE 390 14 -
ADSLQLEKEVVRVWFC OC3N_RAT 390 14 -
ADSLQLEKEVVRVWFC PO3B_XENLA 330 14 -
ADSLQLEKEVVRVWFC ZP47_BRARE 326 14 -
ADNLQLEKEVVRVWFC O57514 367 14 -
ADNLQLEKEVVRVWFC ZP23_BRARE 364 14 -
ADNLQLEKEVVRVWFC ZP12_BRARE 367 14 -
ADSLQLEKEVVRVWFC CF1A_DROME 377 14 -
ADSLQLEKEVVRVWFC SGF3_BOMMO 275 14 -
ADSLQLEKEVVRVWFC O17487 294 14 -
ADSLQLEKEVVRVWFC BRN4_HUMAN 312 14 -
ADSLQLEKEVVRVWFC POU2_XENLA 169 14 -
ADSLQLEKEVVRVWFC O73629 301 14 -
ADSLQLEKEVVRVWFC BRN4_MOUSE 312 14 -
ADSLQLEKEVVRVWFC OCT6_HUMAN 370 14 -
ADSLQLEKEVVRVWFC OCT6_MOUSE 371 14 -
ADSLQLEKEVVRVWFC OCT6_RAT 373 14 -
ADSLQLEKEVVRVWCC PO3A_XENLA 327 14 -
ADSLQLEKEVVRVWFC O73861 317 14 -
ADSLQLEKEVVRVWFC POU1_XENLA 301 14 -
ADNLQLEKEVVRVWFC POU1_BRARE 364 14 -
AGTLQLEKEVVRVWFC ZP50_BRARE 313 14 -
AMELQLEKEVVRVWFC HM06_CAEEL 134 14 -
AEKLSLEKEVVRVWFC POU1_DUGJA 385 14 -
AEKLSLEKEVVRVWFC Q94551 386 14 -
ADQLSMEKEVVRVWFC O42276 310 15 -
AEQLSMEKEVVRVWFC SK1A_RAT 308 14 -
AEQLSMEKEVVRVWFC SK1I_RAT 226 14 -
AEQLNMEKEVIRVWFC O13007 333 14 -
ADQLNMEKEVVRVWFC O57602 336 15 -
AEQLHMEKEVIRVWFC OCT2_HUMAN 330 14 -
AEQLHMEKEVIRVWFC OCT2_MOUSE 314 14 -
AEQLHMEKEVIRVWFC OCT2_PIG 331 14 -
AEQLHMEKEVIRVWFC Q16648 331 14 -
ADRLSMEKEVVRVWFC PDM1_DROME 557 14 -
AEQLNMEKEVIRVWFC OCT1_MOUSE 416 14 -
AEQLNMEKEVIRVWFC O13006 333 14 -
ADQLNMEKEVIRVWFC OCT1_CHICK 409 14 -
ADQLNMEKEVIRVWFC OCT1_HUMAN 413 14 -
ADQLNMEKEVIRVWFC OCT1_XENLA 431 14 -
ADQLNMEKEVIRVWFC Q29076 415 14 -
ADQLNMEKEVIRVWFC Q91809 429 14 -
AEELNLEKEVVRVWFC HMP1_MOUSE 248 14 -
AEELNLEKEVVRVWFC HMP1_BOVIN 248 14 -
AEELNLEKEVVRVWFC Q28503 274 14 -
AEELNLEKEVVRVWFC O75757 274 14 -
AEELNLEKEVVRVWFC HMP1_RAT 274 14 -
AEELNLEKEVVRVWFC HMP1_HUMAN 248 14 -
AEQLSMEKEVVRVWFC OC11_MOUSE 308 14 -
AEGLNLEKEVVRVWFC O57599 283 14 -
AEELNLEKEVVRVWFC HMP1_SHEEP 248 14 -
AEELNLEKEVVSVWFC O18807 248 14 -
SDDLGLERDVVRVWFC POU2_BRARE 377 14 -
AEGLNLEKEVVRVWFC HMP1_MELGA 326 14 -
SERLNMDKEVIRVWFC PDM2_DROME 425 14 -
AEGLHLEKEVVRVWFC HMP1_ONCKE 312 14 -
AEGLHLEKEVVRVWFC HMP1_ONCMY 316 14 -
AEGLHLEKEVVRVWFC Q98978 316 14 -
AEELNLEKEVVRFWFC HMP1_PIG 248 14 -
AKGLHLEKEVVRVWFC Q91441 318 14 -
AQQLGLEKDVVRVWFC OC3A_HUMAN 264 14 -
AQQLGLEKDVVRVWFC OC3B_HUMAN 169 14 -
AEGLHLEKEVVRVWFC Q91481 316 14 -
AEGLHLEKEVVRVWFC Q91485 316 14 -
ANQLGLEKDVVRVWFC OCT3_MOUSE 257 14 -
ARELNMEKDVVRVWFC Q03917 346 14 -
AEKLDLKKNVVRVWFC BR3A_HUMAN 393 14 -
AEKLDLKKNVVRVWFC BR3A_MOUSE 391 14 -
AEKLDLKKNVVRVWFC BR3B_HUMAN 380 14 -
AEKLDLKKNVVRVWFC BR3B_MOUSE 381 14 -
AEKLDLKKNVVRVWFC O77214 354 14 -
AQQLGLEKDVVRVWFC Q06416 263 13 -
AEKLDLKKNVVRVWFC BRN3_CHICK 311 14 -
AEKLDLKKNVVRVWFC IPOU_DROME 325 14 -
AKELNMDKDVVRVWFC Q99293 355 14 -
AEKLDLKKNVVRVWFC BR3C_HUMAN 308 14 -
AEKLDLKKNVVRVWFC BR3C_MOUSE 308 14 -
AEKLDLKKNVVRVWFC O60557 308 14 -
AKELSLEKDVVRVWFC Q03916 330 14 -
AKELSLEKDVVRVWFC Q91989 330 14 -
ADRLDLKKNVVRVWFC UN86_CAEEL 397 14 -
ADKLDLKKNVVRVWFC O18452 387 14 -
ANSLELDRDVVRVWFC HM18_CAEEL 455 14 -
AKELNYDREVVRVWFC PO61_HUMAN 268 14 -
AKELNYDREVVRVWFC PO61_RAT 268 14 -
AKELNYDREVVRVWFC PO61_MOUSE 268 14 -
AGRLRLQKDLVQVWFS SPM1_RAT 239 14 -
AKELNYDREVVRVWFC POUC_BRARE 577 14 -
AEKLNYDREVVRVWFC P78425 598 14 -
AEKLNYDREVVRVWFC P78424 634 14 -