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PR01768

Identifier
TRPVRECEPTOR  [View Relations]  [View Alignment]  
Accession
PR01768
No. of Motifs
10
Creation Date
02-JUL-2002  (UPDATE 12-MAR-2003)
Title
Vanilloid receptor (TRPV) family signature
Database References
PRINTS; PR00167 CACHANNEL; PR01769 VRL2RECEPTOR
Literature References
1. ZHU, X., JIANG, M., PEYTON, M., BOULAY, G., HURST, R., STEFANI, E. AND
BIRNBAUMER, L. 
Trp, a novel mammalian gene family essential for agonist-activated 
capacitative Ca2+ entry.
CELL 85 661-671 (1996).
 
2. BOULAY, G., ZHU, X., PEYTON, M., JIANG, M., HURST, R., STEFANI, E. AND
BIRNBAUMER, L.
Cloning and expression of a novel mammalian homolog of Drosophila transient 
receptor potential (Trp) involved in calcium entry secondary to activation 
of receptors coupled by the Gq class of G protein.
J.BIOL.CHEM. 272 29672-29680 (1997).
 
3. GUNTHORPE, M.J., BENHAM, C.D., RANDALL, A. AND DAVIS, J.B.
The diversity in the vanilloid (TRPV) receptor family of ion channels.
TRENDS PHARMACOL.SCI. 23(4) 183-191 (2002).

Documentation
Transient receptor potential (Trp) and related proteins are thought to be
Ca2+ ion channel subunits that mediate capacitative Ca2+ entry in response 
to a range of external and internal cell stimuli. Such Ca2+ entry is thought 
to be an essential component of cellular responses to many hormones and
growth factors, and acts to replenish intracellular Ca2+ stores that have
been emptied through the action of inositol triphosphate (IP3) and other 
agents. In non-excitable cells (i.e., those that lack voltage-gated Ca2+
channels, such as hepatocytes), this mode of Ca2+ entry is thought to be an
important step in generating the oscillations of intracellular Ca2+
concentration that characterise their response to stimulatory agents [1].
 
Studies on the visual transduction system in Drosophila led to the molecular
cloning of Trp and of a related protein, Trp-like, which show similarity to 
voltage-gated Ca2+ channels in the regions known as S3-S6, including the S5-
S6 linker, which forms the ion-selective channel pore [2]. This provided 
evidence that Trp and/or related proteins might form mammalian capacitative 
Ca2+ entry channels. The sequences of these proteins have varying lengths 
(usually 800-1000 amino acid residues), and hydropathy plots suggest they 
have 6 or more transmembrane (TM) domains, flanked by cytosolic N- and C-
termini In addition, most contain N-terminal ankyrin repeats [2,3]. 
 
Following the cloning of the vanilloid receptor (VR1), at least 4 other
related proteins have been identified. Together, these form a distinct
subgroup of the Trp family. Members of the vanilloid receptor family (TRPV)
are activated by a diverse range of stimuli, including heat, protons,
lipids, phorbols, phosphorylation, changes in extracellular osmolarity
and/or pressure, and depletion of intracellular calcium stores [3]. To date,
2 vanilloid receptor-like proteins (VRL-1 and VRL-2) and at least 2 
epithelial calcium channels (ECAC) have been reported.
 
TRPVRECEPTOR is a 10-element fingerprint that provides a signature for the
vanilloid receptor (TRPV) family. The fingerprint was derived from an
initial alignment of 5 sequences: the motifs were drawn from conserved
regions spanning virtually the full alignment length, focusing on those
sections that characterise the TRPV family but distinguish them from closely
related members of the ECAC channel family. Two iterations on SPTR40_20f 
were required to reach convergence, at which point a true set comprising 25 
sequences was identified. Several partial matches were also found: Q9H303, 
Q9Z182 and Q9JLM0 are closely related channel proteins that fail to make 
significant matches with one or more motifs; and Q95LU9 is a hypothetical 
protein from the crab-eating macaque, which matches motifs 8 and 10.
Summary Information
  25 codes involving 10 elements
0 codes involving 9 elements
0 codes involving 8 elements
1 codes involving 7 elements
0 codes involving 6 elements
2 codes involving 5 elements
0 codes involving 4 elements
0 codes involving 3 elements
1 codes involving 2 elements
Composite Feature Index
1025252525252525252525
90000000000
80000000000
71111111000
60000000000
50000022222
40000000000
30000000000
20000000101
12345678910
True Positives
O35433        Q91XR5        Q96Q92        Q96RS7        
Q99K71 Q9DFS3 Q9EPK8 Q9EQZ4
Q9ERZ7 Q9ERZ8 Q9ES76 Q9H0G9
Q9H304 Q9HBA0 Q9HBC0 Q9JM56
Q9JM57 Q9JMI8 Q9NQ74 Q9NY22
Q9QYH8 Q9WTR1 Q9WUD2 Q9Y5S1
Q9Y670
True Positive Partials
Codes involving 7 elements
Q9H303
Codes involving 5 elements
Q9JLM0 Q9Z182
Codes involving 2 elements
Q95LU9
Sequence Titles
O35433      VANILLOID RECEPTOR SUBTYPE 1 - Rattus norvegicus (Rat). 
Q91XR5 VANILLOID RECEPTOR-LIKE PROTEIN 2 - Mus musculus (Mouse).
Q96Q92 VANILLOID RECEPTOR LIKE CHANNEL-2 - Homo sapiens (Human).
Q96RS7 VANILLOID RECEPTOR-LIKE PROTEIN 2 - Homo sapiens (Human).
Q99K71 VANILLOID RECEPTOR-LIKE PROTEIN 1 - Mus musculus (Mouse).
Q9DFS3 VANILLOID RECEPTOR-RELATED OSMOTICALLY ACTIVATED CHANNEL PROTEIN - Gallus gallus (Chicken).
Q9EPK8 TRANSIENT RECEPTOR POTENTIAL PROTEIN 12 - Mus musculus (Mouse).
Q9EQZ4 ION CHANNEL - Mus musculus (Mouse).
Q9ERZ7 VANILLOID RECEPTOR-RELATED OSMOTICALLY ACTIVATED CHANNEL - Mus musculus (Mouse).
Q9ERZ8 VANILLOID RECEPTOR-RELATED OSMOTICALLY ACTIVATED CHANNEL - Rattus norvegicus (Rat).
Q9ES76 OTRPC4 CATION CHANNEL - Mus musculus (Mouse).
Q9H0G9 HYPOTHETICAL 94.9 KDA PROTEIN - Homo sapiens (Human).
Q9H304 CAPSAICIN RECEPTOR - Homo sapiens (Human).
Q9HBA0 VANILLOID RECEPTOR-RELATED OSMOTICALLY ACTIVATED CHANNEL - Homo sapiens (Human).
Q9HBC0 OTRPC4 - Homo sapiens (Human).
Q9JM56 VANILLOID RECEPTOR TYPE 1 LIKE PROTEIN 2 - Rattus norvegicus (Rat).
Q9JM57 VANILLOID RECEPTOR TYPE 1 LIKE PROTEIN 1 - Rattus norvegicus (Rat).
Q9JMI8 ION CHANNEL - Rattus norvegicus (Rat).
Q9NQ74 VANILLOID RECEPTOR 1 - Homo sapiens (Human).
Q9NY22 VANILLOID RECEPTOR 1 - Homo sapiens (Human).
Q9QYH8 STRETCH ACTIVATED CHANNEL 2B - Rattus norvegicus (Rat).
Q9WTR1 GROWTH FACTOR REGULATED CALCIUM CHANNEL - Mus musculus (Mouse).
Q9WUD2 VANILLOID RECEPTOR-LIKE PROTEIN 1 - Rattus norvegicus (Rat).
Q9Y5S1 VANILLOID RECEPTOR-LIKE PROTEIN 1 - Homo sapiens (Human).
Q9Y670 VANILLOID RECEPTOR-LIKE PROTEIN - Homo sapiens (Human).

Q9H303 CAPSAICIN RECEPTOR VARIANT - Homo sapiens (Human).

Q9JLM0 VANILLOID RECEPTOR SPLICE VARIANT - Rattus norvegicus (Rat).
Q9Z182 STRETCH-INHIBITABLE NONSELECTIVE CHANNEL (SIC) - Rattus norvegicus (Rat).

Q95LU9 HYPOTHETICAL 22.7 KDA PROTEIN - Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey).
Scan History
SPTR40_20f 2  100  NSINGLE    
Initial Motifs
Motif 1  width=28
Element Seqn Id St Int Rpt
KRLTDEEFREPSTGKTCLPKALLNLSNG Q96Q92 178 178 -
KRLTDEEFREPSTGKTCLPKALLNLSNG Q96RS7 110 110 -
KRLTDEEFREPSTGKTCLPKALLNLSNG Q91XR5 110 110 -
KYLTDSAYTEGSTGKTCLMKAVLNLQDG Q99K71 99 99 -
KYLTDSAYTEGSTGKTCLMKAVLNLQDG Q9WTR1 99 99 -

Motif 2 width=22
Element Seqn Id St Int Rpt
NDTIPVLLDIAERTGNMREFIN Q96Q92 207 1 -
NDTIPVLLDIAERTGNMREFIN Q96RS7 139 1 -
NDTIPVLLDIAERTGNMREFIN Q91XR5 139 1 -
NACILPLLQIDRDSGNPQPLVN Q99K71 128 1 -
NACILPLLQIDRDSGNPQPLVN Q9WTR1 128 1 -

Motif 3 width=19
Element Seqn Id St Int Rpt
ERRCKHYVELLVAQGADVH Q96Q92 247 18 -
ERRCKHYVELLVAQGADVH Q96RS7 179 18 -
ERRCKHYVELLVAQGADVH Q91XR5 179 18 -
EKRSLWCVKLLVENGANVH Q99K71 168 18 -
EKRSLWCVKLLVENGANVH Q9WTR1 168 18 -

Motif 4 width=18
Element Seqn Id St Int Rpt
TNQPHIVNYLTENPHKKA Q96Q92 295 29 -
TNQPHIVNYLTENPHKKA Q96RS7 227 29 -
TNQPHIVNYLTENPHKKA Q91XR5 227 29 -
TKQWDVVTYLLENPHQPA Q99K71 215 28 -
TKQWDVVTYLLENPHQPA Q9WTR1 215 28 -

Motif 5 width=24
Element Seqn Id St Int Rpt
DNTRENTKFVTKMYDLLLLKCARL Q96Q92 333 20 -
DNTRENTKFVTKMYDLLLLKCARL Q96RS7 265 20 -
DNTRENTKFVTKMYDLLLLKCSRL Q91XR5 265 20 -
DNSPENSALVIHMYDSLLQMGARL Q99K71 253 20 -
DNSPENSALVIHMYDSLLQMGARL Q9WTR1 253 20 -

Motif 6 width=21
Element Seqn Id St Int Rpt
KIENRHEMLAVEPINELLRDK Q96Q92 442 85 -
KIENRHEMLAVEPINELLRDK Q96RS7 374 85 -
KIENRHEMLAVEPINELLRDK Q91XR5 374 85 -
KSPHRHRMVVLEPLNKLLQEK Q99K71 360 83 -
KSPHRHRMVVLEPLNKLLQEK Q9WTR1 360 83 -

Motif 7 width=17
Element Seqn Id St Int Rpt
FTLTAYYQPLEGTPPYP Q96Q92 485 22 -
FTLTAYYQPLEGTPPYP Q96RS7 417 22 -
FTLTAYYQPLEGTPPYP Q91XR5 417 22 -
FTIVAYHQPSLEQPAIP Q99K71 402 21 -
FTIVAYHQPSLEQPAIP Q9WTR1 402 21 -

Motif 8 width=24
Element Seqn Id St Int Rpt
LDLFKLTIGMGDLEMLSSTKYPVV Q96Q92 671 169 -
LDLFKLTIGMGDLEMLSSTKYPVV Q96RS7 603 169 -
LDLFKLTIGMGDLEMLSSAKYPVV Q91XR5 603 169 -
LELFKFTIGMGELAFQEQLRFRGV Q99K71 593 174 -
LELFKFTIGMGELAFQEQLRFRGV Q9WTR1 593 174 -

Motif 9 width=21
Element Seqn Id St Int Rpt
GEMVTVGKSSDGTPDRRWCFR Q96Q92 759 64 -
GEMVTVGKSSDGTPDRRWCFR Q96RS7 691 64 -
GEMVTVGKSSDGTPDRRWCFR Q91XR5 691 64 -
GRLLKVGTKGDGIPDERWCFR Q99K71 681 64 -
GRLLKVGTKGDGIPDERWCFR Q9WTR1 681 64 -

Motif 10 width=20
Element Seqn Id St Int Rpt
VDEVNWSHWNQNLGIINEDP Q96Q92 780 0 -
VDEVNWSHWNQNLGIINEDP Q96RS7 712 0 -
VDEVNWSHWNQNLGIINEDP Q91XR5 712 0 -
VEEVNWAAWEKTLPTLSEDP Q99K71 702 0 -
VEEVNWAAWEKTLPTLSEDP Q9WTR1 702 0 -
Final Motifs
Motif 1  width=28
Element Seqn Id St Int Rpt
KRLTDEEFREPSTGKTCLPKALLNLSNG Q96Q92 178 178 -
KRLTDEEFREPSTGKTCLPKALLNLSNG Q96RS7 110 110 -
KRLTDEEFREPSTGKTCLPKALLNLSNG Q9HBC0 178 178 -
KRLTDEEFREPSTGKTCLPKALLNLSNG Q91XR5 110 110 -
KRLTDEEFREPSTGKTCLPKALLNLSNG Q9EPK8 178 178 -
KRLTDEEFREPSTGKTCLPKALLNLSNG Q9ERZ7 180 180 -
KRLTDEEFREPSTGKTCLPKALLNLSNG Q9ERZ8 178 178 -
KRLTDEEFREPSTGKTCLPKALLNLSNG Q9ES76 178 178 -
KRLTDEEFREPSTGKTCLPKALLNLSNG Q9HBA0 178 178 -
KRLTDEEFREPSTGKTCLPKALLNLSNG Q9EQZ4 178 178 -
KRLTDEEFREPSTGKTCLPKALLNLSAG Q9DFS3 164 164 -
KRLTDSEFKDPETGKTCLLKAMLNLHNG Q9JM56 141 141 -
KRLTDSEFKDPETGKTCLLKAMLNLHNG O35433 141 141 -
KRLTDSEFKDPETGKTCLLKAMLNLHNG Q9JM57 141 141 -
KHLTDNEFKDPETGKTCLLKAMLNLHDG Q9H0G9 142 142 -
KHLTDNEFKDPETGKTCLLKAMLNLHDG Q9NQ74 142 142 -
KHLTDNEFKDPETGKTCLLKAMLNLHDG Q9NY22 142 142 -
KHLTDNEFKDPETGKTCLLKAMLNLHDG Q9H304 142 142 -
KYLTDSAYTEGSTGKTCLMKAVLNLQDG Q9WUD2 104 104 -
KYLTDSAYTEGSTGKTCLMKAVLNLQDG Q9JMI8 104 104 -
KYLTDSAYTEGSTGKTCLMKAVLNLQDG Q9QYH8 104 104 -
KYLTDSAYTEGSTGKTCLMKAVLNLQDG Q99K71 99 99 -
KYLTDSAYTEGSTGKTCLMKAVLNLQDG Q9WTR1 99 99 -
KYLTDSEYTEGSTGKTCLMKAVLNLKDG Q9Y5S1 103 103 -
KYLTDSEYTEGSTGKTCLMKAVLNLKDG Q9Y670 103 103 -

Motif 2 width=22
Element Seqn Id St Int Rpt
NDTIPVLLDIAERTGNMREFIN Q96Q92 207 1 -
NDTIPVLLDIAERTGNMREFIN Q96RS7 139 1 -
NDTIPVLLDIAERTGNMREFIN Q9HBC0 207 1 -
NDTIPVLLDIAERTGNMREFIN Q91XR5 139 1 -
NDTIPVLLDIAERTGNMREFIN Q9EPK8 207 1 -
NDTIPVLLDIAERTGNMREFIN Q9ERZ7 209 1 -
NDTIPVLLDIAERTGNMREFIN Q9ERZ8 207 1 -
NDTIPVLLDIAERTGNMREFIN Q9ES76 207 1 -
NDTIPVLLDIAERTGNMREFIN Q9HBA0 207 1 -
NDTLQVLLDIAERTGNMREFIN Q9EQZ4 207 1 -
NDTIPILLDIAEKTGNMREFIN Q9DFS3 193 1 -
NDTIALLLDVARKTDSLKQFVN Q9JM56 170 1 -
NDTIALLLDVARKTDSLKQFVN O35433 170 1 -
NDTIALLLDVARKTDSLKQFVN Q9JM57 170 1 -
NTTIPLLLEIARQTDSLKELVN Q9H0G9 171 1 -
NTTIPLLLEIARQTDSLKELVN Q9NQ74 171 1 -
NTTIPLLLEIARQTDSLKELVN Q9NY22 171 1 -
NTTIPLLLEIARQTDSLKELVN Q9H304 171 1 -
NACIMPLLQIDKDSGNPKPLVN Q9WUD2 133 1 -
NACIMPLLQIDKDSGNPKLLVN Q9JMI8 133 1 -
NACIMPLLQIDKDSGNPKLLVN Q9QYH8 133 1 -
NACILPLLQIDRDSGNPQPLVN Q99K71 128 1 -
NACILPLLQIDRDSGNPQPLVN Q9WTR1 128 1 -
NACILPLLQIDRDSGNPQPLVN Q9Y5S1 132 1 -
NACILPLLQIDRDSGNPQPLVN Q9Y670 132 1 -

Motif 3 width=19
Element Seqn Id St Int Rpt
ERRCKHYVELLVAQGADVH Q96Q92 247 18 -
ERRCKHYVELLVAQGADVH Q96RS7 179 18 -
ERRCKHYVELLVAQGADVH Q9HBC0 247 18 -
ERRCKHYVELLVAQGADVH Q91XR5 179 18 -
ERRCKHYVELLVAQGADVH Q9EPK8 247 18 -
ERRCKHYVELLVAQGADVH Q9ERZ7 249 18 -
ERRCKHYVELLVAQGADVH Q9ERZ8 247 18 -
ERRCKHYVELLVAQGADVH Q9ES76 247 18 -
ERRCKHYVELLVAQGADVH Q9HBA0 247 18 -
ERRCKHYVELLVAQGADVH Q9EQZ4 247 18 -
ERRCKHYVELLVEKGADVH Q9DFS3 233 18 -
ERRNMTLVTLLVENGADVQ Q9JM56 210 18 -
ERRNMTLVTLLVENGADVQ O35433 210 18 -
ERRNMTLVTLLVENGADVQ Q9JM57 210 18 -
ERRNMALVTLLVENGADVQ Q9H0G9 211 18 -
ERRNMALVTLLVENGADVQ Q9NQ74 211 18 -
ERRNMALVTLLVENGADVQ Q9NY22 211 18 -
ERRNMALVTLLVENGADVQ Q9H304 211 18 -
EKRSLQCVKLLVENGADVH Q9WUD2 173 18 -
EKRSLQCVKLLVENGADVH Q9JMI8 173 18 -
EKRSLQCVKLLVENGADVH Q9QYH8 173 18 -
EKRSLWCVKLLVENGANVH Q99K71 168 18 -
EKRSLWCVKLLVENGANVH Q9WTR1 168 18 -
EKRSLQCVKLLVENGANVH Q9Y5S1 172 18 -
EKRSLQCVKLLVENGANVH Q9Y670 172 18 -

Motif 4 width=18
Element Seqn Id St Int Rpt
TNQPHIVNYLTENPHKKA Q96Q92 295 29 -
TNQPHIVNYLTENPHKKA Q96RS7 227 29 -
TNQPHIVNYLTENPHKKA Q9HBC0 295 29 -
TNQPHIVNYLTENPHKKA Q91XR5 227 29 -
TNQPHIVNYLTENPHKKA Q9EPK8 295 29 -
TNQPHIVNYLTENPHKKA Q9ERZ7 297 29 -
TNQPHIVNYLTENPHKKA Q9ERZ8 295 29 -
TNQPHIVNYLTENPHKKA Q9ES76 295 29 -
TNQPHIVNYLTENPHKKA Q9HBA0 295 29 -
TNQPHIVNYLTENPHKKA Q9EQZ4 295 29 -
TNQPHIVHYLTENGHKQA Q9DFS3 281 29 -
TNQLAIVKFLLQNSWQPA Q9JM56 258 29 -
TNQLAIVKFLLQNSWQPA O35433 258 29 -
TNQLAIVKFLLQNSWQPA Q9JM57 258 29 -
TNQLGIVKFLLQNSWQTA Q9H0G9 259 29 -
TNQLGIVKFLLQNSWQTA Q9NQ74 259 29 -
TNQLGIVKFLLQNSWQTA Q9NY22 259 29 -
TNQLGIVKFLLQNSWQTA Q9H304 259 29 -
TKQWDVVTYLLENPHQPA Q9WUD2 220 28 -
TKQWDVVTYLLENPHQPA Q9JMI8 220 28 -
TKQWDVVTYLLENPHQPA Q9QYH8 220 28 -
TKQWDVVTYLLENPHQPA Q99K71 215 28 -
TKQWDVVTYLLENPHQPA Q9WTR1 215 28 -
TKQWDVVSYLLENPHQPA Q9Y5S1 219 28 -
TKQWDVVSYLLENPHQPA Q9Y670 219 28 -

Motif 5 width=24
Element Seqn Id St Int Rpt
DNTRENTKFVTKMYDLLLLKCARL Q96Q92 333 20 -
DNTRENTKFVTKMYDLLLLKCARL Q96RS7 265 20 -
DNTRENTKFVTKMYDLLLLKCARL Q9HBC0 333 20 -
DNTRENTKFVTKMYDLLLLKCSRL Q91XR5 265 20 -
DNTRENTKFVTKMYDLLLLKCSRL Q9EPK8 333 20 -
DNTRENTKFVTKMYDLLLLKCSRL Q9ERZ7 335 20 -
DNTRENTKFVTKMYDLLLLKCSRL Q9ERZ8 333 20 -
DNTRENTKFVTKMYDLLLLKCSRL Q9ES76 333 20 -
DNTRENTKFVTKMYDLLLLKCARL Q9HBA0 333 20 -
DNTRENTKFVTKMYDLLLLKCSRL Q9EQZ4 333 20 -
DNTRENTKFVTKMYDLLLIKCAKL Q9DFS3 319 20 -
DNTVDNTKFVTSMYNEILILGAKL Q9JM56 296 20 -
DNTVDNTKFVTSMYNEILILGAKL O35433 296 20 -
DNTVDNTKFVTSMYNEILILGAKL Q9JM57 296 20 -
DNTADNTKFVTSMYNEILILGAKL Q9H0G9 297 20 -
DNTADNTKFVTSMYNEILILGAKL Q9NQ74 297 20 -
DNTADNTKFVTSMYNEILILGAKL Q9NY22 297 20 -
DNTADNTKFVTSMYNEILMLGAKL Q9H304 297 20 -
DNSPENSALVIHMYDGLLQMGARL Q9WUD2 258 20 -
DNSPENSALVIHMYDGLLQMGARL Q9JMI8 258 20 -
DNSPENSALVIHMYDGLLQMGARL Q9QYH8 258 20 -
DNSPENSALVIHMYDSLLQMGARL Q99K71 253 20 -
DNSPENSALVIHMYDSLLQMGARL Q9WTR1 253 20 -
DNSAENIALVTSMYDGLLQAGARL Q9Y5S1 257 20 -
DNSAENIALVTSMYDGLLQAGARL Q9Y670 257 20 -

Motif 6 width=21
Element Seqn Id St Int Rpt
KIENRHEMLAVEPINELLRDK Q96Q92 442 85 -
KIENRHEMLAVEPINELLRDK Q96RS7 374 85 -
KIENRHEMLAVEPINELLRDK Q9HBC0 442 85 -
KIENRHEMLAVEPINELLRDK Q91XR5 374 85 -
KIENRHEMLAVEPINELLRDK Q9EPK8 442 85 -
KIENRHEMLAVEPINELLRDK Q9ERZ7 444 85 -
KIENRHEMLAVEPINELLRDK Q9ERZ8 442 85 -
KIENRHEMLAVEPINELLRDK Q9ES76 442 85 -
KIENRHEMLAVEPINELLRDK Q9HBA0 442 85 -
KIENRHEMLAVEPINELLRDK Q9EQZ4 442 85 -
KIENRHEMLAVEPINELLRDK Q9DFS3 428 85 -
KIGNRHDMLLVEPLNRLLQDK Q9JM56 345 25 -
ETPNRHDMLLVEPLNRLLQDK O35433 405 85 -
ETPNRHDMLLVEPLNRLLQDK Q9JM57 405 85 -
ETPNRHDMLLVEPLNRLLQDK Q9H0G9 406 85 -
ETPNRHDMLLVEPLNRLLQDK Q9NQ74 406 85 -
ETPNRHDMLLVEPLNRLLQDK Q9NY22 406 85 -
ETPNRHDMLLVEPLNRLLQDK Q9H304 406 85 -
KSPNRHRMVVLEPLNKLLQEK Q9WUD2 365 83 -
KSPNRHRMVVLEPLNKLLQEK Q9JMI8 365 83 -
KSPNRHRMVVLEPLNKLLQEK Q9QYH8 365 83 -
KSPHRHRMVVLEPLNKLLQEK Q99K71 360 83 -
KSPHRHRMVVLEPLNKLLQEK Q9WTR1 360 83 -
KSPHRHRMVVLEPLNKLLQAK Q9Y5S1 363 82 -
KSPHRHRMVVLEPLNKLLQAK Q9Y670 363 82 -

Motif 7 width=17
Element Seqn Id St Int Rpt
FTLTAYYQPLEGTPPYP Q96Q92 485 22 -
FTLTAYYQPLEGTPPYP Q96RS7 417 22 -
FTLTAYYQPLEGTPPYP Q9HBC0 485 22 -
FTLTAYYQPLEGTPPYP Q91XR5 417 22 -
FTLTAYYQPLEGTPPYP Q9EPK8 485 22 -
FTLTAYYQPLEGTPPYP Q9ERZ7 487 22 -
FTLTAYYQPLEGTPPYP Q9ERZ8 485 22 -
FTLTAYYQPLEGTPPYP Q9ES76 485 22 -
FTLTAYYQPLEGTPPYP Q9HBA0 485 22 -
FTLTAYYQPLEGTPPYP Q9EQZ4 485 22 -
FTLIAYYRPMEGPPPYP Q9DFS3 471 22 -
FTAAAYYRPVEGLPPYK Q9JM56 388 22 -
FTAAAYYRPVEGLPPYK O35433 448 22 -
FTAAAYYRPVEGLPPYK Q9JM57 448 22 -
FTMAAYYRPVDGLPPFK Q9H0G9 449 22 -
FTMAAYYRPVDGLPPFK Q9NQ74 449 22 -
FTMAAYYRPVDGLPPFK Q9NY22 449 22 -
FTMAAYYRPVDGLPPFK Q9H304 449 22 -
FTVVAYHQPSLDQPAIP Q9WUD2 407 21 -
FTVVAYHQPSLDQPAIP Q9JMI8 407 21 -
FTVVAYHQPSLDQPAIP Q9QYH8 407 21 -
FTIVAYHQPSLEQPAIP Q99K71 402 21 -
FTIVAYHQPSLEQPAIP Q9WTR1 402 21 -
FTAVAYHQPTLKKQAAP Q9Y5S1 405 21 -
FTAVAYHQPTLKKQAAP Q9Y670 405 21 -

Motif 8 width=24
Element Seqn Id St Int Rpt
LDLFKLTIGMGDLEMLSSTKYPVV Q96Q92 671 169 -
LDLFKLTIGMGDLEMLSSTKYPVV Q96RS7 603 169 -
LDLFKLTIGMGDLEMLSSTKYPVV Q9HBC0 671 169 -
LDLFKLTIGMGDLEMLSSAKYPVV Q91XR5 603 169 -
LDLFKLTIGMGDLEMLSSAKYPVV Q9EPK8 671 169 -
LDLFKLTIGMGDLEMLSSAKYPVV Q9ERZ7 673 169 -
LDLFKLTIGMGDLEMLSSAKYPVV Q9ERZ8 671 169 -
LDLFKLTIGMGDLEMLSSAKYPVV Q9ES76 671 169 -
LDLFKLTIGMGDLEMLSSTKYPVV Q9HBA0 671 169 -
LDLFKLTIGMGDLEMLSSAKYPVV Q9EQZ4 671 169 -
LDLFKLTIGMGDLEMLESAKYPGV Q9DFS3 657 169 -
LELFKFTIGMGDLEFTENYDFKAV Q9JM56 575 170 -
LELFKFTIGMGDLEFTENYDFKAV O35433 635 170 -
LELFKFTIGMGDLEFTENYDFKAV Q9JM57 635 170 -
LELFKFTIGMGDLEFTENYDFKAV Q9H0G9 636 170 -
LELFKFTIGMGDLEFTENYDFKAV Q9NQ74 636 170 -
LELFKFTIGMGDLEFTENYDFKAV Q9NY22 636 170 -
LELFKFTIGMGDLEFTENYDFKAV Q9H304 636 170 -
LELFKFTIGMGELAFQEQLRFRGV Q9WUD2 598 174 -
LELFKFTIGMGELAFQEQLRFRGV Q9JMI8 598 174 -
LELFKFTIGMGELAFQEQLRFRGV Q9QYH8 598 174 -
LELFKFTIGMGELAFQEQLRFRGV Q99K71 593 174 -
LELFKFTIGMGELAFQEQLRFRGV Q9WTR1 593 174 -
LELFKFTIGMGELAFQEQLHFRGM Q9Y5S1 598 176 -
LELFKFTIGMGELAFQEQLHFRGM Q9Y670 598 176 -

Motif 9 width=21
Element Seqn Id St Int Rpt
GEMVTVGKSSDGTPDRRWCFR Q96Q92 759 64 -
GEMVTVGKSSDGTPDRRWCFR Q96RS7 691 64 -
GEMVTVGKSSDGTPDRRWCFR Q9HBC0 759 64 -
GEMVTVGKSSDGTPDRRWCFR Q91XR5 691 64 -
GEMVTVGKSSDGTPDRRWCFR Q9EPK8 759 64 -
GEMVTVGKSSDGTPDRRWCFR Q9ERZ7 761 64 -
GEMVTVGKSSDGTPDRRWCFR Q9ERZ8 759 64 -
GEMVTVGKSSDGTPDRRWCFR Q9ES76 759 64 -
GEMVTVGKSSDGTPDRRWCFR Q9HBA0 759 64 -
GEMVTVGKSSDGTPDRRWCFR Q9EQZ4 759 64 -
GEMVTVGKGTDGTPDRRWCFR Q9DFS3 745 64 -
GKLLQVGFTPDGQDDYRWCFR Q9JM56 663 64 -
GKLLQVGFTPDGKDDYRWCFR O35433 723 64 -
GKLLQVGFTPDGKDDYRWCFR Q9JM57 723 64 -
GKLLQVGYTPDGKDDYRWCFR Q9H0G9 724 64 -
GKLLQVGYTPDGKDDYRWCFR Q9NQ74 724 64 -
GKLLQVGYTPDGKDDYRWCFR Q9NY22 724 64 -
GKLLQVGYTPDGKDDYRWCFR Q9H304 724 64 -
GRLLKVGTRGDGTPDERWCFR Q9WUD2 686 64 -
GRLLKVGTRGDGTPDERWCFR Q9JMI8 686 64 -
GRLLKVGTRGDGTPDERWCFR Q9QYH8 686 64 -
GRLLKVGTKGDGIPDERWCFR Q99K71 681 64 -
GRLLKVGTKGDGIPDERWCFR Q9WTR1 681 64 -
GVMLTVGTKPDGSPDERWCFR Q9Y5S1 685 63 -
GVMLTVGTKPDGSPDERWCFR Q9Y670 685 63 -

Motif 10 width=20
Element Seqn Id St Int Rpt
VDEVNWSHWNQNLGIINEDP Q96Q92 780 0 -
VDEVNWSHWNQNLGIINEDP Q96RS7 712 0 -
VDEVNWSHWNQNLGIINEDP Q9HBC0 780 0 -
VDEVNWSHWNQNLGIINEDP Q91XR5 712 0 -
VDEVNWSHWNQNLGIINEDP Q9EPK8 780 0 -
VDEVNWSHWNQNLGIINEDP Q9ERZ7 782 0 -
VDEVNWSHWNQNLGIINEDP Q9ERZ8 780 0 -
VDEVNWSHWNQNLGIINEDP Q9ES76 780 0 -
VNEVNWSHWNQNLGIINEDP Q9HBA0 780 0 -
VDEVSWSHWNQNLGIINEDP Q9EQZ4 780 0 -
VDEVNWSHWNQNLGIISEDP Q9DFS3 766 0 -
VDEVNWTTWNTNVGIINEDP Q9JM56 684 0 -
VDEVNWTTWNTNVGIINEDP O35433 744 0 -
VDEVNWTTWNTNVGIINEDP Q9JM57 744 0 -
VDEVNWTTWNTNVGIINEDP Q9H0G9 745 0 -
VDEVNWTTWNTNVGIINEDP Q9NQ74 745 0 -
VDEVNWTTWNTNVGIINEDP Q9NY22 745 0 -
VDEVNWTTWNTNVGIINEDP Q9H304 745 0 -
VEEVNWAAWEKTLPTLSEDP Q9WUD2 707 0 -
VEEVNWAAWEKTLPTLSEDP Q9JMI8 707 0 -
VEEVNWAAWEKTLPTLSEDP Q9QYH8 707 0 -
VEEVNWAAWEKTLPTLSEDP Q99K71 702 0 -
VEEVNWAAWEKTLPTLSEDP Q9WTR1 702 0 -
VEEVNWASWEQTLPTLCEDP Q9Y5S1 706 0 -
VEEVNWASWEQTLPTLCEDP Q9Y670 706 0 -