| Identifier | TRNASYNTHMET [View Relations] [View Alignment]
|
| Accession | PR01041 |
| No. of Motifs | 6 |
| Creation Date | 11-DEC-1998 (UPDATE 28-JUN-1999) |
| Title | Methionyl-tRNA synthetase signature |
| Database References | PRINTS; PR90000 TRNASYNTH; PR90001 TRNASYNTHCLI
PROSITE; PS00178 AA_TRNA_LIGASE_I
BLOCKS; BL00178
INTERPRO; IPR002304
PDB; 1MEA; 1MED
SCOP; 1MEA; 1MED |
| Literature References | 1. LODISH, H., BALTIMORE, D., BERK, A., ZIPURSKY, S.L., MATSUDAIRA, P. AND
DARNELL, J.
Nucleic Acids, the Genetic Code, and Protein Synthesis.
IN MOLECULAR CELL BIOLOGY, SCIENTIFIC AMERICAN BOOKS (NEW YORK), 1995,
PP.126-128.
2. DELARUE, M.
Aminoacyl-tRNA synthetases.
CURR.OPIN.STRUCT.BIOL. 5 48-55 (1995).
3. PERONA, J.J., ROULD, M. AND STEITZ, T.A.
Structural Basis for Transfer RNA Aminoacylation by Escherichia coli
Glutaminyl-tRNA Synthetase.
BIOCHEMISTRY 32 8758-8771 (1993).
|
| Documentation | Appropriate attachment of an amino acid to its cognate tRNA is the key to
faithful translation of the genetic code. The family of enzymes responsible
for this is the aminoacyl-tRNA synthetases (AATRSs) (EC 6.1.1.-).
AATRSs catalyse a two-step reaction:
(1) Enzyme + amino acid + ATP ---> Enzyme(aminoacyl-AMP) + PPi
(2) tRNA + Enzyme(aminoacyl-AMP) ---> aminoacyl-tRNA + AMP + Enzyme
In the first step, they form an aminoacyl-adenylate, in which the carboxyl
of the amino acid is linked to the alpha-phosphate of ATP, by displacing
the pyrophosphate. When the correct tRNA is bound, the aminoacyl group is
transferred to the 2'- or 3'-terminal OH of the tRNA at the expense of AMP
[1].
Based on structural and sequence comparisons, this group of at least 20
proteins (in prokaryotes there are approximately 20, but in eukaryotes
there are usually 2 forms for each amino acid; namely, the cytosolic and
mitochondrial forms) can be divided into two classes.
Class I AATRSs contain a characteristic Rossman fold and are mostly
monomeric. At the primary structure level, two highly-conserved motifs
are observed, `HIGH' and `KMSKS' [2,3]; these are associated with the ATP-
binding site.
Class II AATRSs share an anti-parallel beta-sheet formation, flanked by
alpha-helices [3], and are mostly dimeric or multimeric.
Further distinction between the two classes is evident when the reaction
mechanisms are investigated. In reactions catalysed by the class I AATRSs,
the aminoacyl group is coupled to the 2'-hydroxyl of the tRNA, while, in
class II reactions, the 3'-hydroxyl site is preferred.
Methionly-tRNA synthetase (EC 6.1.1.10) is specific to methionine and
belongs to class I.
TRNASYNTHMET is a 6-element fingerprint that provides a signature for the
methionyl-tRNA synthetases. The fingerprint was derived from an initial
alignment of 11 sequences: the motifs were drawn from the N-terminal and
central portions of the alignment - motif 1 spans part of the region encoded
by the PROSITE pattern AA_TRNA_LIGASE_I (PS00178), which contains the `HIGH'
consensus sequence; a zinc binding site lies between motifs 3 and 4. Three
iterations on OWL31.1 were required to reach convergence, at which point a
true set comprising 27 sequences was identified. Two partial matches were
also found, SYM_MYCPU and AB006140, both of which are fragments that lack
the portion of sequence bearing motif 6.
An update on SPTR37_9f identified a true set of 27 sequences, and 11
partial matches.
|
| Summary Information | 27 codes involving 6 elements
0 codes involving 5 elements
0 codes involving 4 elements
0 codes involving 3 elements
11 codes involving 2 elements
|
| Composite Feature Index | | 6 | 27 | 27 | 27 | 27 | 27 | 27 | | 5 | 0 | 0 | 0 | 0 | 0 | 0 | | 4 | 0 | 0 | 0 | 0 | 0 | 0 | | 3 | 0 | 0 | 0 | 0 | 0 | 0 | | 2 | 11 | 9 | 0 | 0 | 0 | 2 | | 1 | 2 | 3 | 4 | 5 | 6 |
|
| True Positives | O13634 O14000 O23761 O33925
O58721 O67298 O74634 O84035
SYMC_YEAST SYMM_YEAST SYM_ARCFU SYM_BACST
SYM_BACSU SYM_BORBU SYM_CAEEL SYM_ECOLI
SYM_HAEIN SYM_HELPY SYM_HUMAN SYM_METJA
SYM_METTH SYM_MYCGE SYM_MYCPN SYM_MYCTU
SYM_SYNY3 SYM_THETH SYM_TREPA |
| True Positive Partials | |
| Sequence Titles | O13634 METHIONYL-TRNA SYNTHETASE - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
O14000 PUTATIVE METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
O23761 METRS (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METHIONYL-TRNA SYNTHETASE) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O33925 METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - THERMOTOGA MARITIMA.
O58721 723AA LONG HYPOTHETICAL METHIONYL-TRNA SYNTHETASE - PYROCOCCUS HORIKOSHII.
O67298 METHIONYL-TRNA SYNTHETASE ALPHA SUBUNIT - AQUIFEX AEOLICUS.
O74634 METHIONYL-TRNA SYNTHETASE, MITOCHONDRIAL (EC 6.1.1.10) (METHIONINE-- TRNA LIGASE) (METRS) - CANDIDA ALBICANS (YEAST).
O84035 METHIONYL-TRNA SYNTHETASE - CHLAMYDIA TRACHOMATIS.
SYMC_YEAST METHIONYL-TRNA SYNTHETASE, CYTOPLASMIC (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
SYMM_YEAST METHIONYL-TRNA SYNTHETASE, MITOCHONDRIAL (EC 6.1.1.10) (METHIONINE-- TRNA LIGASE) (METRS) - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
SYM_ARCFU METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - ARCHAEOGLOBUS FULGIDUS.
SYM_BACST METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - BACILLUS STEAROTHERMOPHILUS.
SYM_BACSU METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - BACILLUS SUBTILIS.
SYM_BORBU METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
SYM_CAEEL PROBABLE METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - CAENORHABDITIS ELEGANS.
SYM_ECOLI METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - ESCHERICHIA COLI.
SYM_HAEIN METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - HAEMOPHILUS INFLUENZAE.
SYM_HELPY METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).
SYM_HUMAN METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - HOMO SAPIENS (HUMAN).
SYM_METJA METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - METHANOCOCCUS JANNASCHII.
SYM_METTH METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - METHANOBACTERIUM THERMOAUTOTROPHICUM.
SYM_MYCGE METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - MYCOPLASMA GENITALIUM.
SYM_MYCPN METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - MYCOPLASMA PNEUMONIAE.
SYM_MYCTU METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - MYCOBACTERIUM TUBERCULOSIS.
SYM_SYNY3 METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
SYM_THETH METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - THERMUS AQUATICUS (SUBSP. THERMOPHILUS).
SYM_TREPA METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - TREPONEMA PALLIDUM.
O75005 VALYL-TRNA SYNTHETASE, MITOCHONDRIAL PRECURSOR - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
Q12019 HYPOTHETICAL 559.3 KD PROTEIN - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
SYIM_YEAST ISOLEUCYL-TRNA SYNTHETASE, MITOCHONDRIAL (EC 6.1.1.5) (ISOLEUCINE-- TRNA LIGASE) (ILERS) - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
SYI_ECOLI ISOLEUCYL-TRNA SYNTHETASE (EC 6.1.1.5) (ISOLEUCINE--TRNA LIGASE) (ILERS) - ESCHERICHIA COLI.
SYI_HELPY ISOLEUCYL-TRNA SYNTHETASE (EC 6.1.1.5) (ISOLEUCINE--TRNA LIGASE) (ILERS) - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).
SYI_SYNY3 ISOLEUCYL-TRNA SYNTHETASE (EC 6.1.1.5) (ISOLEUCINE--TRNA LIGASE) (ILERS) - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
SYLM_SACDO LEUCYL-TRNA SYNTHETASE, MITOCHONDRIAL PRECURSOR (EC 6.1.1.4) (LEUCINE--TRNA LIGASE) (LEURS) - SACCHAROMYCES DOUGLASII (YEAST).
SYV_ARCFU VALYL-TRNA SYNTHETASE (EC 6.1.1.9) (VALINE--TRNA LIGASE) (VALRS) - ARCHAEOGLOBUS FULGIDUS.
SYV_METJA VALYL-TRNA SYNTHETASE (EC 6.1.1.9) (VALINE--TRNA LIGASE) (VALRS) - METHANOCOCCUS JANNASCHII.
SYV_METTH VALYL-TRNA SYNTHETASE (EC 6.1.1.9) (VALINE--TRNA LIGASE) (VALRS) - METHANOBACTERIUM THERMOAUTOTROPHICUM.
YLJ6_CAEEL HYPOTHETICAL 272.0 KD PROTEIN C50C3.6 IN CHROMOSOME III - CAENORHABDITIS ELEGANS.
|
| Scan History | OWL31_1 3 50 NSINGLE
SPTR37_9f 2 120 NSINGLE
|
| Initial Motifs | Motif 1 width=14
Element Seqn Id St Int Rpt
VTTPLYYVNDVPHL SYM_SYNY3 11 11 -
VTTPIYYVNAEPHL SYM_THETH 7 7 -
LTTPIYYPSDKLHI SYM_BACST 8 8 -
ITTPIYYVNDIPHI SYM_HELPY 6 6 -
ITTPIYYPSGKLHI SYM_BACSU 10 10 -
ITSALPYVNNVPHL SYM_HUMAN 268 268 -
ITTPIYYASGKPHI SYM_MYCGE 6 6 -
VTTPIFYPNAKPHL SYMM_YEAST 17 17 -
ITTALAYTNGPLHL SYM_METJA 5 5 -
VTCALPYANGAIHL SYM_HAEIN 10 10 -
VTCALPYANGSIHL SYM_ECOLI 9 9 -
Motif 2 width=15
Element Seqn Id St Int Rpt
QGYDVLMITGTDEHG SYM_SYNY3 43 18 -
DGYRTFFLTGTDEHG SYM_THETH 39 18 -
RGYDVMYLTGTDEHG SYM_BACST 40 18 -
QGEEVFFLTGTDEHG SYM_HELPY 38 18 -
KGFDVRYLTGTDEHG SYM_BACSU 42 18 -
RQWNTLYLCGTDEYG SYM_HUMAN 301 19 -
NGYEAFLLVGSDEHG SYM_MYCGE 38 18 -
KGNLSFFTTGTDEHG SYMM_YEAST 49 18 -
RGEDVIHVGGTDNHG SYM_METJA 38 19 -
RGNKIHFVCADDAHG SYM_HAEIN 42 18 -
RGHEVNFICADDAHG SYM_ECOLI 41 18 -
Motif 3 width=12
Element Seqn Id St Int Rpt
ILYDRFSRTTDP SYM_SYNY3 91 33 -
IAYDDFIRTTEE SYM_THETH 87 33 -
ISYDDFIRTTQE SYM_BACST 88 33 -
LDYDGFIRTTDS SYM_HELPY 86 33 -
ISNDDFIRTTEK SYM_BACSU 90 33 -
ISFDIFGRTTTP SYM_HUMAN 349 33 -
ISFDHFIRTTDE SYM_MYCGE 86 33 -
INYTRFIRTTDP SYMM_YEAST 98 34 -
VEFDAFGKTHSQ SYM_METJA 86 33 -
ISFDNYHSTHSE SYM_HAEIN 90 33 -
ISYDNYHSTHSE SYM_ECOLI 89 33 -
Motif 4 width=12
Element Seqn Id St Int Rpt
IYVWFDALLGYV SYM_SYNY3 228 125 -
TYVWFDALLNYV SYM_THETH 224 125 -
IYVWIDALANYI SYM_BACST 224 124 -
VYVWLDALLNYA SYM_HELPY 228 130 -
VYVWIDALFNYL SYM_BACSU 237 135 -
FYVWFDATIGYL SYM_HUMAN 515 154 -
IYVWFDALFSYI SYM_MYCGE 221 123 -
VYVWFDALCNYL SYMM_YEAST 244 134 -
MYVWLEAPIGYI SYM_METJA 244 146 -
FYVWLDAPIGYM SYM_HAEIN 251 149 -
FYVWLDAPIGYM SYM_ECOLI 250 149 -
Motif 5 width=16
Element Seqn Id St Int Rpt
HLIGKDILRFHAVYWP SYM_SYNY3 264 24 -
HLIGKDILKPHAVFWP SYM_THETH 255 19 -
HLVGKEIVRFHTIYWP SYM_BACST 257 21 -
HIVGKDILRFHAIYWP SYM_HELPY 260 20 -
HLVGKEIVRFHTIYWP SYM_BACSU 270 21 -
QFMAKDNVPFHSLVFP SYM_HUMAN 550 23 -
HLISREITRFHCIYWP SYM_MYCGE 259 26 -
HVIGKDIAKFHTVYWP SYMM_YEAST 300 44 -
HFIGKDITVHHAVFWP SYM_METJA 278 22 -
HFIGKDIVYFHSLFWP SYM_HAEIN 290 27 -
HFIGKDIVYFHSLFWP SYM_ECOLI 291 29 -
Motif 6 width=12
Element Seqn Id St Int Rpt
DLANDLGNLLNR SYM_SYNY3 356 76 -
DLADDLGNLVQR SYM_THETH 348 77 -
DLANDLGNLLHR SYM_BACST 349 76 -
NLNNDLGNLLNR SYM_HELPY 352 76 -
DLANDLGNLLNR SYM_BACSU 362 76 -
ELLNNLGNFINR SYM_HUMAN 645 79 -
DLANSFGNHVSR SYM_MYCGE 352 77 -
LLVSKWGNLINR SYMM_YEAST 391 75 -
ELINIIGNFTHR SYM_METJA 371 77 -
DIVNKLVNLASR SYM_HAEIN 383 77 -
DIVNKVVNLASR SYM_ECOLI 384 77 -
|
| Final Motifs | Motif 1 width=14
Element Seqn Id St Int Rpt
VTTPLYYVNDVPHL SYM_SYNY3 11 11 -
LTTPLYYVNAPPHM O23761 73 73 -
VTTPIYYVNDVPHL O67298 9 9 -
ITTPIYYVNSEPHI O33925 5 5 -
VTTAIAYPNAAPHV SYM_MYCTU 6 6 -
VTTPIYYVNAEPHL SYM_THETH 7 7 -
LTTPIYYPSDKLHI SYM_BACST 8 8 -
ITTPIYYVNDIPHI SYM_HELPY 6 6 -
ITTPIYYPSGKLHI SYM_BACSU 10 10 -
VTSALPYANGPIHA O58721 6 6 -
ITTPIYYASGKPHI SYM_MYCPN 6 6 -
ITSALPYVNNVPHL O13634 21 21 -
ITCALPYANGPTHL SYM_METTH 6 6 -
ITSALPYVNNVPHL SYMC_YEAST 199 199 -
ITSALPYVNNVPHL SYM_HUMAN 268 268 -
ITAALPYVNNVPHL SYM_TREPA 6 6 -
ITAALPYVNNVPHL SYM_CAEEL 39 39 -
ITTPIYYASGKPHI SYM_MYCGE 6 6 -
VTAALPYVNNIPHL SYM_BORBU 7 7 -
VTTPIFYPNAKPHL SYMM_YEAST 17 17 -
LTTPIFYVNAAPHL O14000 23 23 -
ITSALPYANGPLHF O84035 8 8 -
ITTPIFYVNAAPHI O74634 22 22 -
ITTALAYTNGPLHL SYM_METJA 5 5 -
VTCGLPYANGKAHV SYM_ARCFU 4 4 -
VTCALPYANGAIHL SYM_HAEIN 10 10 -
VTCALPYANGSIHL SYM_ECOLI 9 9 -
Motif 2 width=15
Element Seqn Id St Int Rpt
QGYDVLMITGTDEHG SYM_SYNY3 43 18 -
LGKKVIFITGTDEHG O23761 105 18 -
RDYDVFFLTGTDEHG O67298 41 18 -
MGYDVFFLTGTDEHG O33925 37 18 -
DRYDVRFLTGTDEHG SYM_MYCTU 38 18 -
DGYRTFFLTGTDEHG SYM_THETH 39 18 -
RGYDVMYLTGTDEHG SYM_BACST 40 18 -
QGEEVFFLTGTDEHG SYM_HELPY 38 18 -
KGFDVRYLTGTDEHG SYM_BACSU 42 18 -
KGEDVVFICGTDEHG O58721 39 19 -
NGYEAYFLTGTDEHG SYM_MYCPN 38 18 -
RNHNTLYICGTDEYG O13634 54 19 -
RGDDVLFVCATDEHG SYM_METTH 39 19 -
RNYNALFICGTDEYG SYMC_YEAST 232 19 -
RQWNTLYLCGTDEYG SYM_HUMAN 301 19 -
RGYHTCFVCGTDEYG SYM_TREPA 38 18 -
RGHQTFYVGGTDEYG SYM_CAEEL 72 19 -
NGYEAFLLVGSDEHG SYM_MYCGE 38 18 -
SGIETLYVCGTDEYG SYM_BORBU 39 18 -
KGNLSFFTTGTDEHG SYMM_YEAST 49 18 -
PDVSVISSTGTDEHG O14000 56 19 -
QGKEVLYICGSDEYG O84035 41 19 -
PSKESFMLTGTDEHG O74634 55 19 -
RGEDVIHVGGTDNHG SYM_METJA 38 19 -
SGEEVVFVCGSDCHG SYM_ARCFU 36 18 -
RGNKIHFVCADDAHG SYM_HAEIN 42 18 -
RGHEVNFICADDAHG SYM_ECOLI 41 18 -
Motif 3 width=12
Element Seqn Id St Int Rpt
ILYDRFSRTTDP SYM_SYNY3 91 33 -
IAYDKFIRTTDP O23761 153 33 -
IEYTKFIRTTDP O67298 89 33 -
ITNDYFIRTTDE O33925 85 33 -
ISFDRFIRTTDA SYM_MYCTU 86 33 -
IAYDDFIRTTEE SYM_THETH 87 33 -
ISYDDFIRTTQE SYM_BACST 88 33 -
LDYDGFIRTTDS SYM_HELPY 86 33 -
ISNDDFIRTTEK SYM_BACSU 90 33 -
ISFDFFGRTELP O58721 87 33 -
INFDHFIRTTDL SYM_MYCPN 86 33 -
IDFDHFGRTTTP O13634 102 33 -
ISFDSFTRTTDE SYM_METTH 87 33 -
IGFDYFGRTTTD SYMC_YEAST 280 33 -
ISFDIFGRTTTP SYM_HUMAN 349 33 -
LSFDYFGRTTSD SYM_TREPA 86 33 -
IDFSHFGRTTTD SYM_CAEEL 120 33 -
ISFDHFIRTTDE SYM_MYCGE 86 33 -
IEFDIFGRTTNK SYM_BORBU 87 33 -
INYTRFIRTTDP SYMM_YEAST 98 34 -
TKFTHFIRTTNP O14000 104 33 -
ISVDFFSRTTNT O84035 89 33 -
VNYDRFIRTTDN O74634 103 33 -
VEFDAFGKTHSQ SYM_METJA 86 33 -
IKFDFYGRTDSD SYM_ARCFU 84 33 -
ISFDNYHSTHSE SYM_HAEIN 90 33 -
ISYDNYHSTHSE SYM_ECOLI 89 33 -
Motif 4 width=12
Element Seqn Id St Int Rpt
IYVWFDALLGYV SYM_SYNY3 228 125 -
IYVWFDALLGYI O23761 289 124 -
IYVWFDALFNYI O67298 227 126 -
IYVWVDALINYI O33925 224 127 -
MYVWVDALTNYL SYM_MYCTU 225 127 -
TYVWFDALLNYV SYM_THETH 224 125 -
IYVWIDALANYI SYM_BACST 224 124 -
VYVWLDALLNYA SYM_HELPY 228 130 -
VYVWIDALFNYL SYM_BACSU 237 135 -
LYVWFEAPIGYI O58721 251 152 -
IYVWFDALFNYI SYM_MYCPN 221 123 -
LYVWFDATIGYI O13634 268 154 -
IYVWGEAFLGYI SYM_METTH 249 150 -
LYVWFDATIGYV SYMC_YEAST 446 154 -
FYVWFDATIGYL SYM_HUMAN 515 154 -
FYVWFDAPVGYI SYM_TREPA 250 152 -
FYVWFDAPIGYL SYM_CAEEL 288 156 -
IYVWFDALFSYI SYM_MYCGE 221 123 -
FYVWFDAPIGYI SYM_BORBU 252 153 -
VYVWFDALCNYL SYMM_YEAST 244 134 -
IYVWLDALINYI O14000 251 135 -
FYVWFDAPIGYI O84035 248 147 -
IYVWFDALLNYL O74634 249 134 -
MYVWLEAPIGYI SYM_METJA 244 146 -
VYVWVDAPIGYI SYM_ARCFU 243 147 -
FYVWLDAPIGYM SYM_HAEIN 251 149 -
FYVWLDAPIGYM SYM_ECOLI 250 149 -
Motif 5 width=16
Element Seqn Id St Int Rpt
HLIGKDILRFHAVYWP SYM_SYNY3 264 24 -
HLIGKDILRFHAVYWP O23761 325 24 -
HLVGKDILRFHTVYWP O67298 254 15 -
HLIGKEINRFHSIIWP O33925 256 20 -
HMIGKDIIRFHAVYWP SYM_MYCTU 258 21 -
HLIGKDILKPHAVFWP SYM_THETH 255 19 -
HLVGKEIVRFHTIYWP SYM_BACST 257 21 -
HIVGKDILRFHAIYWP SYM_HELPY 260 20 -
HLVGKEIVRFHTIYWP SYM_BACSU 270 21 -
HFIGKDNIPFHAIFWP O58721 293 30 -
HLISREITRFHCIYWP SYM_MYCPN 259 26 -
QFMGKDNVPFHTVIFP O13634 303 23 -
HFIGKDIIYHHAIFWP SYM_METTH 284 23 -
QFMGKDNVPFHTVVFP SYMC_YEAST 481 23 -
QFMAKDNVPFHSLVFP SYM_HUMAN 550 23 -
QFVGKDNIPFHTLFFP SYM_TREPA 301 39 -
NFVGKDNVAFHAVMFP SYM_CAEEL 324 24 -
HLISREITRFHCIYWP SYM_MYCGE 259 26 -
QFIGKDNILFHTIIFP SYM_BORBU 287 23 -
HVIGKDIAKFHTVYWP SYMM_YEAST 300 44 -
HVIGKDIIRFHCIYWP O14000 285 22 -
QFIGKDNTSFHAAIFP O84035 288 28 -
HVIGKDIIRFHCIYWP O74634 288 27 -
HFIGKDITVHHAVFWP SYM_METJA 278 22 -
HFIGLDIVYHHCIFWP SYM_ARCFU 281 26 -
HFIGKDIVYFHSLFWP SYM_HAEIN 290 27 -
HFIGKDIVYFHSLFWP SYM_ECOLI 291 29 -
Motif 6 width=12
Element Seqn Id St Int Rpt
DLANDLGNLLNR SYM_SYNY3 356 76 -
HLANTIGNLLNR O23761 417 76 -
ELANEIGNLYSR O67298 346 76 -
DLANDYGNLLHR O33925 348 76 -
DLANELGNLAQR SYM_MYCTU 350 76 -
DLADDLGNLVQR SYM_THETH 348 77 -
DLANDLGNLLHR SYM_BACST 349 76 -
NLNNDLGNLLNR SYM_HELPY 352 76 -
DLANDLGNLLNR SYM_BACSU 362 76 -
ELVNNLGNFVHR O58721 395 86 -
DLANSFGNHASR SYM_MYCPN 352 77 -
ELLANLGNFVNR O13634 398 79 -
ELADVLGNFLHR SYM_METTH 376 76 -
ELLANLGNFVNR SYMC_YEAST 576 79 -
ELLNNLGNFINR SYM_HUMAN 645 79 -
ELIGNLCNLVNR SYM_TREPA 396 79 -
ELLNNLGNFINR SYM_CAEEL 419 79 -
DLANSFGNHVSR SYM_MYCGE 352 77 -
ELIDNFSNLVNR SYM_BORBU 382 79 -
LLVSKWGNLINR SYMM_YEAST 391 75 -
DLRRSLGVLLSR O14000 377 76 -
ELVGKYGNFVNR O84035 382 78 -
AVLGKYCNLISR O74634 379 75 -
ELINIIGNFTHR SYM_METJA 371 77 -
EVIATLGNFLYR SYM_ARCFU 375 78 -
DIVNKLVNLASR SYM_HAEIN 383 77 -
DIVNKVVNLASR SYM_ECOLI 384 77 -
|