| Literature References | 1. LINDER, M.E. AND GILMAN, A.G.
G proteins.
SCI.AM. 267 56 (1992).
2. KAZIRO, Y., ITOH, H., KOZASA, T., NAKAFUKU, M. AND SATOH, T.
Structure and function of signal-transducing GTP-binding proteins.
ANNU.REV.BIOCHEMISTRY 60 349-400 (1991).
3. SIMON, M.I., STRATHMANN, M.P. AND GAUTAM, N.
Diversity of G proteins in signal transduction.
SCIENCE 252 802-808 (1993).
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| Documentation | Guanine nucleotide binding proteins (G proteins) are a family of membrane-
associated proteins that couple extracellularly-activated integral-membrane
receptors to intracellular effectors, such as ion channels and enzymes that
vary the concentration of second messenger molecules [1-3]. G proteins are
composed of 3 subunits (alpha, beta and gamma) which, in the resting state,
associate as a trimer at the inner face of the plasma membrane. The alpha
subunit has a molecule of guanosine diphosphate (GDP) bound to it:
stimulation of the G protein by an activated receptor leads to its exchange
for GTP (guanosine triphosphate). This results in the separation of the
alpha from the beta and gamma subunits, which always remain tightly
associated as a dimer. Both the alpha and beta-gamma subunits are then able
to interact with effectors, either individually or in a cooperative manner.
The intrinsic GTPase activity of the alpha subunit hydrolyses the bound GTP
to GDP. This returns the alpha subunit to its inactive conformation and
allows it to reassociate with the beta-gamma subunit, thus restoring the
system to its resting state.
G protein alpha subunits are 350-400 amino acids in length and have
molecular weights in the range 40-45 kDa. Seventeen distinct types of alpha
subunit have been identified in mammals. These fall into 4 main groups on
the basis of both sequence similarity and function: alpha-S, alpha-Q,
alpha-I and alpha-12 [3]. Many alpha subunits are substrates for
ADP-ribosylation by cholera or pertussis toxins. They are often N-terminally
acylated, usually with myristate and/or palmitoylate, and these fatty acid
modifications are probably important for membrane association and high-
affinity interactions with other proteins. The atomic structure of the
alpha subunit of the G protein involved in mammalian vision, transducin,
has been elucidated in both GTP- and GDB-bound forms, and shows considerable
similarity in both primary and tertiary structure in the nucleotide-binding
regions to other G proteins, such as p21-ras and EF-Tu.
GPROTEINA is a 5-element fingerprint that provides a signature for alpha
transducins. The fingerprint was derived from an initial alignment of 7
sequences: the motifs were drawn from conserved regions spanning virtually
the full alignment length, motifs 1, 3 and 5 encoding the GTP-binding
domain [2]. Two iterations on OWL23.2 were required to reach convergence,
at which point a true set comprising 104 sequences was identified. Numerous
partial matches were also found, including 2 alpha transducin fragments
(BOVGTPAA and A30246) and several GTP-binding proteins, such as GTPases
and ADP-ribosylation factors.
An update on SPTR37_9f identified a true set of 166 sequences, and 15
partial matches.
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| Sequence Titles | GB01_BOVIN GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT 1 (GTP-BINDING PROTEIN G3
GB01_DROME GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT (G(O) CLASS-I) - DROSOPHI
GB01_HUMAN GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT 1 - HOMO SAPIENS (HUMAN).
GB01_MOUSE GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT 1 - MUS MUSCULUS (MOUSE).
GB01_RAT GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT 1 - RATTUS NORVEGICUS (RA
GB02_CRILO GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT 2 - CRICETULUS LONGICAUDA
GB02_DROME GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT (G(O) CLASS- II) - DROSOP
GB02_HUMAN GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT 2 - HOMO SAPIENS (HUMAN).
GB02_MOUSE GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT 2 - MUS MUSCULUS (MOUSE).
GB02_RAT GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT 2 - RATTUS NORVEGICUS (RA
GB05_DROME GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT - DROSOPHILA MELANOGASTER
GB0_CAEEL GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT - CAENORHABDITIS ELEGANS.
GB0_HELTI GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT - HELISOMA TRIVOLVIS (SNA
GB0_LOCMI GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT - LOCUSTA MIGRATORIA (MIG
GB0_LYMST GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT - LYMNAEA STAGNALIS (GREA
GB0_MANSE GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT - MANDUCA SEXTA (TOBACCO
GB0_PATYE GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT - PATINOPECTEN YESSOENSIS
GB0_XENLA GUANINE NUCLEOTIDE-BINDING PROTEIN G(O), ALPHA SUBUNIT - XENOPUS LAEVIS (AFRICAN
GB11_BOVIN GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-11 SUBUNIT (GL2) - BOS TAURUS (BOVINE)
GB11_HUMAN GUANINE NUCLEOTIDE-BINDING PROTEIN G(Y), ALPHA SUBUNIT (ALPHA-11) - HOMO SAPIENS
GB11_MELGA GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-11 SUBUNIT - MELEAGRIS GALLOPAVO (COMM
GB11_MOUSE GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-11 SUBUNIT - MUS MUSCULUS (MOUSE).
GB11_XENLA GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-11 SUBUNIT - XENOPUS LAEVIS (AFRICAN C
GB12_HUMAN GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-12 SUBUNIT (G ALPHA 12) - HOMO SAPIENS
GB12_MOUSE GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-12 SUBUNIT (G ALPHA 12) - MUS MUSCULUS
GB13_HUMAN GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-13 SUBUNIT (G ALPHA 13) - HOMO SAPIENS
GB13_MOUSE GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-13 SUBUNIT (G ALPHA 13) - MUS MUSCULUS
GB14_BOVIN GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-14 SUBUNIT (GL1) - BOS TAURUS (BOVINE)
GB14_MOUSE GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-14 SUBUNIT - MUS MUSCULUS (MOUSE).
GB15_HUMAN GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-15 SUBUNIT (ALPHA-16) - HOMO SAPIENS (
GB15_MOUSE GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-15 SUBUNIT - MUS MUSCULUS (MOUSE).
GBA1_ARATH GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT (GP-ALPHA-1) - ARABIDOPSIS TH
GBA1_CAEEL GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT - CAENORHABDITIS ELEGANS.
GBA1_CANAL GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA SUBUNIT - CANDIDA ALBICANS (YEAST).
GBA1_COLTR GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA SUBUNIT - COLLETOTRICHUM TRIFOLII.
GBA1_COPCO GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA SUBUNIT - COPRINUS CONGREGATUS (INKY CA
GBA1_CRYNE GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA SUBUNIT - CRYPTOCOCCUS NEOFORMANS (FILO
GBA1_CRYPA GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA SUBUNIT - CRYPHONECTRIA PARASITICA (CHE
GBA1_DICDI GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT (G ALPHA 1) - DICTYOSTELIUM DISCOIDEUM (SLIME MOLD).
GBA1_EMENI GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA SUBUNIT - EMERICELLA NIDULANS (ASPERGIL
GBA1_LOTJA GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT (GP-ALPHA-1) - LOTUS JAPONICU
GBA1_LUPLU GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT (GP-ALPHA-1) - LUPINUS LUTEUS
GBA1_LYCES GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT (GP-ALPHA-1) - LYCOPERSICON E
GBA1_MAGGR GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA SUBUNIT - MAGNAPORTHE GRISEA (RICE BLAS
GBA1_NEUCR GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT (GP1-ALPHA) - NEUROSPORA CRAS
GBA1_ORYSA GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT (GP-ALPHA-1) - ORYZA SATIVA (
GBA1_PEA GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT (GP-ALPHA-1) - PISUM SATIVUM
GBA1_SCHPO GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT (GP1-ALPHA) - SCHIZOSACCHAROM
GBA1_SOLTU GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT (GP-ALPHA-1) - SOLANUM TUBERO
GBA1_SOYBN GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT (GP-ALPHA-1) - GLYCINE MAX (S
GBA1_USTMA GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT - USTILAGO MAYDIS (SMUT FUNGU
GBA1_YEAST GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT (GP1-ALPHA) - SACCHAROMYCES C
GBA2_CAEEL GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-2 SUBUNIT - CAENORHABDITIS ELEGANS.
GBA2_DICDI GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-2 SUBUNIT (G ALPHA 2) - DICTYOSTELIUM D
GBA2_KLULA GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-2 SUBUNIT (GP2-ALPHA) - KLUYVEROMYCES L
GBA2_NEUCR GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-2 SUBUNIT (GP2-ALPHA) - NEUROSPORA CRAS
GBA2_PEA GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-2 SUBUNIT (GP-ALPHA-2) - PISUM SATIVUM
GBA2_SCHPO GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-2 SUBUNIT (GP2-ALPHA) - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
GBA2_SOYBN GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-2 SUBUNIT (GP-ALPHA-2) - GLYCINE MAX (S
GBA2_USTMA GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-2 SUBUNIT - USTILAGO MAYDIS (SMUT FUNGUS).
GBA2_YEAST GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-2 SUBUNIT (GP2-ALPHA) - SACCHAROMYCES C
GBA3_CAEEL GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-3 SUBUNIT - CAENORHABDITIS ELEGANS.
GBA3_USTHO GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-3 SUBUNIT - USTILAGO HORDEI (SMUT FUNGUS).
GBA3_USTMA GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-3 SUBUNIT - USTILAGO MAYDIS (SMUT FUNGUS).
GBA4_USTMA GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-4 SUBUNIT - USTILAGO MAYDIS (SMUT FUNGUS).
GBA5_DICDI GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT (G ALPHA 5) - DICTYOSTELIUM DISCOIDEUM (SLIME MOLD).
GBA7_DICDI GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-7 SUBUNIT (G ALPHA 7) - DICTYOSTELIUM DISCOIDEUM (SLIME MOLD).
GBA8_DICDI GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-8 SUBUNIT (G ALPHA 8) - DICTYOSTELIUM DISCOIDEUM (SLIME MOLD).
GBAF_DROME GUANINE NUCLEOTIDE-BINDING PROTEIN G(F), ALPHA SUBUNIT - DROSOPHILA MELANOGASTER (FRUIT FLY).
GBAF_HUMAN GUANINE NUCLEOTIDE-BINDING PROTEIN G(OLF), ALPHA SUBUNIT (ADENYLATE CYCLASE-STIM
GBAF_RAT GUANINE NUCLEOTIDE-BINDING PROTEIN G(OLF), ALPHA SUBUNIT (ADENYLATE CYCLASE-STIM
GBAK_CAVPO GUANINE NUCLEOTIDE-BINDING PROTEIN G(K), ALPHA SUBUNIT (G(I) ALPHA-3) - CAVIA PO
GBAK_HUMAN GUANINE NUCLEOTIDE-BINDING PROTEIN G(K), ALPHA SUBUNIT (G(I) ALPHA-3) - HOMO SAP
GBAK_RAT GUANINE NUCLEOTIDE-BINDING PROTEIN G(K), ALPHA SUBUNIT (G(I) ALPHA-3) - RATTUS N
GBAL_DROME GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA SUBUNIT HOMOLOG (PROTEIN CONCERTINA) -
GBAS_BOVIN GUANINE NUCLEOTIDE-BINDING PROTEIN G(S), ALPHA SUBUNIT (ADENYLATE CYCLASE-STIMUL
GBAS_CRILO GUANINE NUCLEOTIDE-BINDING PROTEIN G(S), ALPHA SUBUNIT (ADENYLATE CYCLASE-STIMUL
GBAS_HOMAM GUANINE NUCLEOTIDE-BINDING PROTEIN G(S), ALPHA SUBUNIT (ADENYLATE CYCLASE-STIMUL
GBAS_HUMAN GUANINE NUCLEOTIDE-BINDING PROTEIN G(S), ALPHA SUBUNIT (ADENYLATE CYCLASE-STIMUL
GBAS_LYMST GUANINE NUCLEOTIDE-BINDING PROTEIN G(S), ALPHA SUBUNIT (ADENYLATE CYCLASE-STIMUL
GBAS_MOUSE GUANINE NUCLEOTIDE-BINDING PROTEIN G(S), ALPHA SUBUNIT (ADENYLATE CYCLASE-STIMUL
GBAS_PIG GUANINE NUCLEOTIDE-BINDING PROTEIN G(S), ALPHA SUBUNIT (ADENYLATE CYCLASE-STIMUL
GBAS_SCHMA GUANINE NUCLEOTIDE-BINDING PROTEIN G(S), ALPHA SUBUNIT (ADENYLATE CYCLASE-STIMUL
GBAS_XENLA GUANINE NUCLEOTIDE-BINDING PROTEIN G(S), ALPHA SUBUNIT (ADENYLATE CYCLASE-STIMUL
GBAZ_HUMAN GUANINE NUCLEOTIDE-BINDING PROTEIN G(Z), ALPHA SUBUNIT (G(X) ALPHA CHAIN) - HOMO
GBAZ_RAT GUANINE NUCLEOTIDE-BINDING PROTEIN G(Z), ALPHA SUBUNIT (G(X) ALPHA CHAIN) - RATT
GBI1_CAVPO GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-1 SUBUNIT (ADENYLATE CYCLASE-INHI
GBI1_CHICK GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-1 SUBUNIT (ADENYLATE CYCLASE-INHI
GBI1_HUMAN GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-1 SUBUNIT (ADENYLATE CYCLASE-INHI
GBI1_ORYLA GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-1 SUBUNIT (ADENYLATE CYCLASE-INHI
GBI1_RAT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-1 SUBUNIT (ADENYLATE CYCLASE-INHI
GBI1_XENLA GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-1 SUBUNIT (ADENYLATE CYCLASE-INHI
GBI2_CANFA GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-2 SUBUNIT (ADENYLATE CYCLASE-INHI
GBI2_CAVPO GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-2 SUBUNIT (ADENYLATE CYCLASE-INHI
GBI2_CHICK GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-2 SUBUNIT (ADENYLATE CYCLASE-INHI
GBI2_HUMAN GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-2 SUBUNIT (ADENYLATE CYCLASE-INHI
GBI2_MOUSE GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-2 SUBUNIT (ADENYLATE CYCLASE-INHI
GBI2_RAT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-2 SUBUNIT (ADENYLATE CYCLASE-INHI
GBI_ASTPE GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA SUBUNIT (ADENYLATE CYCLASE-INHIBI
GBI_HELTI GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA SUBUNIT (ADENYLATE CYCLASE-INHIBI
GBI_HOMAM GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA SUBUNIT (ADENYLATE CYCLASE-INHIBI
GBI_LYMST GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA SUBUNIT (ADENYLATE CYCLASE-INHIBI
GBQ1_DROME GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q), ALPHA SUBUNIT ISOFORM 1 (DGQALPHA-1) -
GBQ3_DROME GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q), ALPHA SUBUNIT ISOFORM 3 (DGQALPHA-3) -
GBQ_CANFA GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q), ALPHA SUBUNIT - CANIS FAMILIARIS (DOG).
GBQ_HOMAM GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q), ALPHA SUBUNIT - HOMARUS AMERICANUS (AME
GBQ_HUMAN GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q), ALPHA SUBUNIT - HOMO SAPIENS (HUMAN).
GBQ_LOLFO GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q), ALPHA SUBUNIT - LOLIGO FORBESI (NORTHER
GBQ_LYMST GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q), ALPHA SUBUNIT - LYMNAEA STAGNALIS (GREA
GBQ_MOUSE GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q), ALPHA SUBUNIT - MUS MUSCULUS (MOUSE).
GBQ_PATYE GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q), ALPHA SUBUNIT - PATINOPECTEN YESSOENSIS
GBQ_XENLA GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q), ALPHA SUBUNIT - XENOPUS LAEVIS (AFRICAN
GBS1_DROME GUANINE NUCLEOTIDE-BINDING PROTEIN G(S)-L, ALPHA SUBUNIT (ADENYLATE CYCLASE-STIM
GBS2_DROME GUANINE NUCLEOTIDE-BINDING PROTEIN G(S)-S, ALPHA SUBUNIT (ADENYLATE CYCLASE-STIM
GBT1_BOVIN GUANINE NUCLEOTIDE-BINDING PROTEIN G(T), ALPHA-1 SUBUNIT (TRANSDUCIN ALPHA-1 CHA
GBT1_CANFA GUANINE NUCLEOTIDE-BINDING PROTEIN G(T), ALPHA-1 SUBUNIT (TRANSDUCIN ALPHA-1 CHA
GBT1_HUMAN GUANINE NUCLEOTIDE-BINDING PROTEIN G(T), ALPHA-1 SUBUNIT (TRANSDUCIN ALPHA-1 CHA
GBT1_MOUSE GUANINE NUCLEOTIDE-BINDING PROTEIN G(T), ALPHA-1 SUBUNIT (TRANSDUCIN ALPHA-1 CHA
GBT2_BOVIN GUANINE NUCLEOTIDE-BINDING PROTEIN G(T), ALPHA-2 SUBUNIT (TRANSDUCIN ALPHA-2 CHA
GBT2_HUMAN GUANINE NUCLEOTIDE-BINDING PROTEIN G(T), ALPHA-2 SUBUNIT (TRANSDUCIN ALPHA-2 CHA
GBT2_MOUSE GUANINE NUCLEOTIDE-BINDING PROTEIN G(T), ALPHA-2 SUBUNIT (TRANSDUCIN ALPHA-2 CHA
GBT3_RAT GUANINE NUCLEOTIDE-BINDING PROTEIN G(T), ALPHA-3 SUBUNIT (GUSTDUCIN ALPHA-3 CHAI
GBT_XENLA GUANINE NUCLEOTIDE-BINDING PROTEIN G(T), ALPHA SUBUNIT (TRANSDUCIN ALPHA CHAIN)
O13011 ALPHA 01 SUBUNIT OF HETEROTRIMERIC GTP-BINDING PROTEIN - XENOPUS LAEVIS (AFRICAN
O13055 GI2 ALPHA SUBUNIT - ORYZIAS LATIPES (MEDAKA FISH).
O13314 MAGA - MAGNAPORTHE GRISEA (RICE BLAST FUNGUS).
O13316 MAGC - MAGNAPORTHE GRISEA (RICE BLAST FUNGUS).
O18678 G PROTEIN ALPHA SUBUNIT - CAENORHABDITIS ELEGANS.
O44409 T07A9.7 PROTEIN - CAENORHABDITIS ELEGANS.
O44744 R06A10.2 PROTEIN - CAENORHABDITIS ELEGANS.
O73819 GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-14 SUBUNIT - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
O74204 MOD-D - PODOSPORA ANSERINA.
O74227 GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA SUBUNIT - COCHLIOBOLUS HETEROSTROPHUS (DRECHSLERA MAYDIS).
O74259 G PROTEIN ALPHA SUBUNIT - SPOROTHRIX SCHENCKII.
O74768 GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT - SCHIZOSACCHAROMYCES POMBE (
O76584 C16A11.1 PROTEIN - CAENORHABDITIS ELEGANS.
O82057 G PROTEIN ALPHA SUBUNIT - SPINACIA OLERACEA (SPINACH).
O88302 GTP BINDING PROTEIN ALPHA 15 - RATTUS NORVEGICUS (RAT).
O93564 GUANINE NUCLEOTIDE-BINDING PROTEIN G(O) ALPHA SUBUNIT 1 - XENOPUS LAEVIS (AFRICA
P78705 G PROTEIN ALPHA SUBUNIT - NEUROSPORA CRASSA.
P79895 TRANSDUCIN ALPHA SUBUNIT - SPARUS AURATA (GILTHEAD SEA BREAM).
P91907 GPA-15 PROTEIN - CAENORHABDITIS ELEGANS.
P91955 GQ PROTEIN ALPHA SUBUNIT - LIMULUS POLYPHEMUS (ATLANTIC HORSESHOE CRAB).
Q00581 GUANINE NUCLEOTIDE REGULATORY PROTEIN - CRYPHONECTRIA PARASITICA (CHESNUT BLIGHT FUNGUS) (ENDOTHIA PARASITICA).
Q01706 GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT - PNEUMOCYSTIS CARINII.
Q01711 GUANOSINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT - PNEUMOCYSTIS CARINII.
Q17386 EGL-30 - CAENORHABDITIS ELEGANS.
Q18022 C15C8.7 PROTEIN.
Q18205 GOA-1 PROTEIN - CAENORHABDITIS ELEGANS.
Q18434 ODR-3 PROTEIN - CAENORHABDITIS ELEGANS.
Q18873 SIMILAR TO GUANINE NUCLEOTIDE-BINDING PROTEIN - CAENORHABDITIS ELEGANS.
Q19029 CE. ELEGANS GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-3 SUBUNIT (SP:P28052) - CAENORHABDITIS ELEGANS.
Q19572 SIMILAR TO GUANINE NUCLEOTIDE-BINDING PROTEINS - CAENORHABDITIS ELEGANS.
Q20701 SIMILAR TO THE G-ALPHA FAMILY - CAENORHABDITIS ELEGANS.
Q20907 GPA-8 PROTEIN - CAENORHABDITIS ELEGANS.
Q21917 GPA-7 PROTEIN - CAENORHABDITIS ELEGANS.
Q22567 GPA-1 PROTEIN - CAENORHABDITIS ELEGANS.
Q25408 G PROTEIN ALPHA-A SUBUNIT - LYMNAEA STAGNALIS (GREAT POND SNAIL).
Q43604 G PROTEIN ALPHA SUBUNIT - ORYZA SATIVA (RICE).
Q61939 GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA 11 - MUS MUSCULUS (MOUSE).
Q63210 GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-12 SUBUNIT (G ALPHA 12) - RATTUS NORVEGICUS (RAT).
Q63803 XLAS - RATTUS NORVEGICUS (RAT).
Q90846 G PROTEIN - GALLUS GALLUS (CHICKEN).
Q90847 G PROTEIN ALPHA SUBUNIT - GALLUS GALLUS (CHICKEN).
Q93743 GPA-6 PROTEIN - CAENORHABDITIS ELEGANS.
Q94470 GTP-BINDING PROTEIN ALPHA SUBUNIT - DICTYOSTELIUM DISCOIDEUM (SLIME MOLD).
O01428 SIMILAR TO GUANINE NUCLEOTIDE-BINDING PROTEIN - CAENORHABDITIS ELEGANS.
Q20910 GPA-9 PROTEIN - CAENORHABDITIS ELEGANS.
Q40404 HETEROTRIMERIC G PROTEIN SUBUNIT - NICOTIANA PLUMBAGINIFOLIA (LEADWORT-LEAVED TO
CIN4_YEAST GTP-BINDING PROTEIN CIN4 - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
ARF_AJECA ADP-RIBOSYLATION FACTOR - AJELLOMYCES CAPSULATA (HISTOPLASMA CAPSULATUM).
ARL2_DROME GTP-BINDING ADP-RIBOSYLATION FACTOR HOMOLOG 2 PROTEIN - DROSOPHILA MELANOGASTER (FRUIT FLY).
ARL_SCHPO PUTATIVE ADP-RIBOSYLATION FACTOR-LIKE PROTEIN C22F3.05C - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
GBA_LEIDO GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA SUBUNIT - LEISHMANIA DONOVANI.
O45379 F19H8.3 PROTEIN - CAENORHABDITIS ELEGANS.
O80462 PUTATIVE GUANINE NUCLEOTIDE-BINDING PROTEIN - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O81224 EXTRA-LARGE G-PROTEIN - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O81225 EXTRA-LARGE G-PROTEIN - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O88667 RAS-LIKE GTP-BINDING PROTEIN RAD - MUS MUSCULUS (MOUSE).
Q92788 RAD GTPASE - HOMO SAPIENS (HUMAN).
RAD_HUMAN GTP-BINDING PROTEIN RAD (RAS ASSOCIATED WITH DIABETES) (RAD1) - HOMO SAPIENS (HUMAN).
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