| Identifier | TMFOUR [View Relations] [View Alignment]
|
| Accession | PR00259 |
| No. of Motifs | 4 |
| Creation Date | 19-JUL-1994 (UPDATE 28-JUN-1999) |
| Title | Transmembrane four family signature |
| Database References |
PROSITE; PS00421 TM4
BLOCKS; BL00421
PFAM; PF00335 transmembrane4
INTERPRO; IPR000301
|
| Literature References | 1. LEVY, S., NGUYEN, Q.V., ANDRIA, M.L. AND TAKAHASHI, S.
Structure and membrane topology of TAPA-1.
J.BIOL.CHEM. 266 14597-14602 (1991).
2. TOMLINSON, M.G., WILLIAMS, A.F. AND WRIGHT, M.D.
Epitope mapping of anti-rat CD53 monoclonal antibodies. Implications for
the membrane orientation of the Transmembrane 4 Superfamily.
EUR.J.IMMUNOL. 23 136-140 (1993).
|
| Documentation | A number of eukaryotic cell surface antigens have been shown to be related
[1], including mammalian leukocyte antigen CD37, mammalian lysosomal
membrane protein CD63, human tumour-associated antigen CD-029, and several
others. These proteins are all type II membrane proteins: they contain an
N-terminal transmembrane (TM) domain, which acts both as a signal sequence
and a membrane anchor, and 3 additional TM regions (hence the name `TM4').
The sequences contain a number of conserved cysteine residues.
TMFOUR is a 4-element fingerprint that provides a signature for the
TM4 proteins. The fingerprint was derived from an initial alignment of 8
sequences: the motifs were drawn largely from the TM domains, motifs 2 and
3 spanning the region encoded by PROSITE pattern TM4 (PS00421), which
encompasses the intervening loop. Two iterations on OWL23.2 were required
to reach convergence, at which point a true set comprising 20 sequences was
identified. A single partial match (B35826) was also found, a fragment
lacking part of TM domain 4.
An update on SPTR37_9f identified a true set of 47 sequences, and 6
partial matches.
|
| Summary Information | 47 codes involving 4 elements
3 codes involving 3 elements
3 codes involving 2 elements
|
| Composite Feature Index | |
| True Positives | A15_HUMAN A15_MOUSE C151_HUMAN C151_MOUSE
CD37_HUMAN CD37_MOUSE CD37_RAT CD53_HUMAN
CD53_MOUSE CD53_RAT CD63_HUMAN CD63_MOUSE
CD63_RABIT CD63_RAT CD81_HUMAN CD81_MOUSE
CD82_HUMAN CD82_MOUSE CD9_BOVIN CD9_CERAE
CD9_FELCA CD9_HUMAN CD9_MOUSE CD9_RAT
CO02_HUMAN IM23_SCHHA IM23_SCHJA IM23_SCHMA
NAG2_HUMAN O43657 O55158 O60635
O60636 O60637 O60745 O60746
O70352 O70401 O75954 O76137
O88429 O89118 Q18177 Q19983
Q22495 Q62745 SAS_HUMAN |
| True Positive Partials | |
| Sequence Titles | A15_HUMAN CELL SURFACE GLYCOPROTEIN A15 (T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA ASSOCIATED ANTIGEN 1) (TALLA-1) (MEMBRANE COMPONENT, X CHROMOSOME, SURFACE MARKER 1) - HOMO SAPIENS (HUMAN).
A15_MOUSE CELL SURFACE GLYCOPROTEIN A15 (PE31) (TALLA HOMOLOG) - MUS MUSCULUS (MOUSE).
C151_HUMAN PLATELET-ENDOTHELIAL TETRASPAN ANTIGEN 3 (PETA-3) (GP27) (MEMBRANE GLYCOPROTEIN SFA-1) (CD151 ANTIGEN) - HOMO SAPIENS (HUMAN).
C151_MOUSE PLATELET-ENDOTHELIAL TETRASPAN ANTIGEN 3 (PETA-3) (GP27) (MEMBRANE GLYCOPROTEIN SFA-1) (CD151 ANTIGEN) - MUS MUSCULUS (MOUSE).
CD37_HUMAN LEUKOCYTE ANTIGEN CD37 - HOMO SAPIENS (HUMAN).
CD37_MOUSE LEUKOCYTE ANTIGEN CD37 - MUS MUSCULUS (MOUSE).
CD37_RAT LEUKOCYTE ANTIGEN CD37 - RATTUS NORVEGICUS (RAT).
CD53_HUMAN LEUKOCYTE SURFACE ANTIGEN CD53 (CELL SURFACE GLYCOPROTEIN CD53) - HOMO SAPIENS (HUMAN).
CD53_MOUSE LEUKOCYTE SURFACE ANTIGEN CD53 (CELL SURFACE GLYCOPROTEIN CD53) - MUS MUSCULUS (MOUSE).
CD53_RAT LEUKOCYTE SURFACE ANTIGEN CD53 (CELL SURFACE GLYCOPROTEIN CD53) (LEUKOCYTE ANTIGEN MRC OX-44) - RATTUS NORVEGICUS (RAT).
CD63_HUMAN CD63 ANTIGEN (MELANOMA-ASSOCIATED ANTIGEN ME491) (LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 3) (LAMP-3) (OCULAR MELANOMA-ASSOCIATED ANTIGEN) (OMA81H) (GRANULOPHYSIN) - HOMO SAPIENS (HUMAN).
CD63_MOUSE CD63 ANTIGEN - MUS MUSCULUS (MOUSE).
CD63_RABIT CD63 ANTIGEN - ORYCTOLAGUS CUNICULUS (RABBIT).
CD63_RAT CD63 ANTIGEN (AD1 ANTIGEN) - RATTUS NORVEGICUS (RAT).
CD81_HUMAN CD81 ANTIGEN (26 KD CELL SURFACE PROTEIN TAPA-1) - HOMO SAPIENS (HUMAN).
CD81_MOUSE CD81 ANTIGEN (26 KD CELL SURFACE PROTEIN TAPA-1) - MUS MUSCULUS (MOUSE).
CD82_HUMAN CD82 ANTIGEN (INDUCIBLE MEMBRANE PROTEIN R2) (C33 ANTIGEN) (IA4) (METASTASIS SUPPRESSOR KANGAI 1) (SUPPRESSOR OF TUMORIGENICITY-6) - HOMO SAPIENS (HUMAN).
CD82_MOUSE CD82 ANTIGEN (INDUCIBLE MEMBRANE PROTEIN R2) (C33 ANTIGEN) (IA4) - MUS MUSCULUS (MOUSE).
CD9_BOVIN CD9 ANTIGEN - BOS TAURUS (BOVINE).
CD9_CERAE CD9 ANTIGEN (27 KD DIPHTHERIA TOXIN RECEPTOR-ASSOCIATED PROTEIN) (DRAP27) - CERCOPITHECUS AETHIOPS (GREEN MONKEY) (GRIVET).
CD9_FELCA CD9 ANTIGEN - FELIS SILVESTRIS CATUS (CAT).
CD9_HUMAN CD9 ANTIGEN (P24) (LEUKOCYTE ANTIGEN MIC3) (MOTILITY-RELATED PROTEIN) (MRP-1) - HOMO SAPIENS (HUMAN).
CD9_MOUSE CD9 ANTIGEN - MUS MUSCULUS (MOUSE).
CD9_RAT CD9 ANTIGEN - RATTUS NORVEGICUS (RAT).
CO02_HUMAN TUMOR-ASSOCIATED ANTIGEN CO-029 - HOMO SAPIENS (HUMAN).
IM23_SCHHA 23 KD INTEGRAL MEMBRANE PROTEIN (SH23) - SCHISTOSOMA HAEMATOBIUM (BLOOD FLUKE).
IM23_SCHJA 23 KD INTEGRAL MEMBRANE PROTEIN (SJ23) - SCHISTOSOMA JAPONICUM (BLOOD FLUKE).
IM23_SCHMA 23 KD INTEGRAL MEMBRANE PROTEIN (SM23) - SCHISTOSOMA MANSONI (BLOOD FLUKE).
NAG2_HUMAN NOVEL ANTIGEN 2 (NAG-2) (TSPAN-4) - HOMO SAPIENS (HUMAN).
O43657 T245 PROTEIN - HOMO SAPIENS (HUMAN).
O55158 D6.1A PROTEIN - RATTUS NORVEGICUS (RAT).
O60635 TSPAN-1 - HOMO SAPIENS (HUMAN).
O60636 TSPAN-2 - HOMO SAPIENS (HUMAN).
O60637 TSPAN-3 - HOMO SAPIENS (HUMAN).
O60745 TETRASPAN NET-1 - HOMO SAPIENS (HUMAN).
O60746 TETRASPAN NET-4 - HOMO SAPIENS (HUMAN).
O70352 METASTASIS SUPPRESSOR HOMOLOG - RATTUS NORVEGICUS (RAT).
O70401 TETRASPANIN TSPAN-6 - MUS MUSCULUS (MOUSE).
O75954 TETRASPAN NET-5 - HOMO SAPIENS (HUMAN).
O76137 TM4SF PROTEIN - DROSOPHILA MELANOGASTER (FRUIT FLY).
O88429 CELL SURFACE GLYCOPROTEIN A15 - MUS MUSCULUS (MOUSE).
O89118 PLATELET ENDOTHELIAL TETRASPAN ANTIGEN-3 - MUS MUSCULUS (MOUSE).
Q18177 SIMILAR TO SMALL TYPE-II MEMBRANE ANTIGEN. NCBI GI: 1086714 - CAENORHABDITIS ELEGANS.
Q19983 F33C8.3 PROTEIN - CAENORHABDITIS ELEGANS.
Q22495 T14G10.6 PROTEIN - CAENORHABDITIS ELEGANS.
Q62745 TARGET OF THE ANTIPROLIFERATIVE ANTIBODY - RATTUS NORVEGICUS (RAT).
SAS_HUMAN SARCOMA AMPLIFIED SEQUENCE - HOMO SAPIENS (HUMAN).
O60628 TETRASPANIN TSPAN-5 - HOMO SAPIENS (HUMAN).
Q17526 SIMILAR TO HUMAN INDUCIBLE MEMBRANE PROTEIN R2 - CAENORHABDITIS ELEGANS.
YL11_CAEEL HYPOTHETICAL 35.3 KD PROTEIN C02F12.1 IN CHROMOSOME X - CAENORHABDITIS ELEGANS.
O02138 SIMILAR TO THE FAMILY OF SMALL TYPE-III MEMBRANE ANTIGENS - CAENORHABDITIS ELEGANS.
O44582 F39C12.3 PROTEIN - CAENORHABDITIS ELEGANS.
O46101 EG:8D8.7 PROTEIN - DROSOPHILA MELANOGASTER (FRUIT FLY).
|
| Scan History | OWL23_2 2 100 NSINGLE
OWL28_0 1 100 NSINGLE
SPTR37_9f 3 100 NSINGLE
|
| Initial Motifs | Motif 1 width=24
Element Seqn Id St Int Rpt
YLLFVFNFVFWLAGGVILGVALWL TAPA_HUMAN 12 12 -
YFLFLFNLIFFILGAVILGFGVWI R2_HUMAN 11 11 -
FLLYVLLLAFCACAVGLIAIGVAV AD1_RAT 11 11 -
YLLFGFNFIFWLAGIAVLAIGLWL CD9_CERAE 11 11 -
YLLFGFNFIFWLAGIAVLSVGLWL CD9_BOVIN 11 11 -
YVLFFFNFLFWVCGCCILGFGIHL CD53_RAT 10 10 -
FLLYVLLLAFCACAVGLIAVGVGA CD63_HUMAN 11 11 -
Motif 2 width=27
Element Seqn Id St Int Rpt
FYTGVYILIGAGALMMLVGFLGCCGAV CD9_BOVIN 53 18 -
FYTGVYILIGAGALMMLVGFLGCCGAV CD9_CERAE 55 20 -
GSLLPVVIIAVGAFLFLVAFVGCCGAC AD1_RAT 49 14 -
LRMGAYVFIGVGAVTMLMGFLGCIGAV R2_HUMAN 52 17 -
FYVGIYILIAVGAVMMFVGFLGCYGAI TAPA_HUMAN 58 22 -
GSLLPVVIIAVGVFLFLVAFVGCCGAC CD63_HUMAN 49 14 -
FLTLGNVLVIVGSIIMVVAFLGCMGSI CD53_RAT 48 14 -
Motif 3 width=29
Element Seqn Id St Int Rpt
QESQCLLGTFFTCLVILFACEVAAGIWGF TAPA_HUMAN 85 0 -
KENYCLMITFAIFLSLIMLVEVAVAIAGY AD1_RAT 76 0 -
QESQCMLGLFFGFLLVIFAIEIAAAIWGY CD9_CERAE 82 0 -
QESQCMLGLFFSFLLVIFAIEVAAAIWGY CD9_BOVIN 80 0 -
KENKCLLMSFFVLLLLILLAEVTLAILLF CD53_RAT 75 0 -
KENYCLMITFAIFLSLIMLVEVAAAIAGY CD63_HUMAN 76 0 -
NEVRCLLGLYFAFLLLILIAQVTAGALFY R2_HUMAN 79 0 -
Motif 4 width=27
Element Seqn Id St Int Rpt
LVAGAALGIAFVEVLGIIFSCCLVKSI AD1_RAT 204 99 -
IILGVGVGVAIIELLGMVLSICLCRHV R2_HUMAN 230 122 -
VVAAAALGIAFVEVLGIVFACCLVKSI CD63_HUMAN 204 99 -
YIGIVTICVCVIQVLGMSFALTLNCQI CD53_RAT 183 79 -
IIGAVGIGIAVVMIFGMVFSMILCCAI CD9_BOVIN 192 83 -
IIGAVGIGIAVVMIFGMIFSMILCCAI CD9_CERAE 194 83 -
LIGIAAIVVAVIMIFEMILSMVLCCGI TAPA_HUMAN 204 90 -
|
| Final Motifs | Motif 1 width=24
Element Seqn Id St Int Rpt
YLLFGFNFIFWLAGIAVLAVGLWL CD9_FELCA 11 11 -
YLLFGFNFIFWLAGIAVLAIGLWL CD9_CERAE 11 11 -
YLLFGFNFIFWLAGIAVLAIGLWL CD9_HUMAN 11 11 -
YLLFGFNFIFWLAGIAVLSVGLWL CD9_BOVIN 11 11 -
YLLFGFNFIFWLAGIAVLAIGLWL CD9_MOUSE 11 11 -
YLLFGFNFIFWLAGIAVLAIGLWL CD9_RAT 11 11 -
YLLFVFNFVFWLAGGVILGVALWL CD81_HUMAN 12 12 -
YLLFVFNFVFWLAGGVILGVALWL CD81_MOUSE 12 12 -
YLLFVFNFVFWLAGGVILGVALWL Q62745 12 12 -
YSMFTFNFLFWLCGILILALAIWV CO02_HUMAN 10 10 -
YFLFLFNLIFFILGAVILGFGVWI CD82_HUMAN 11 11 -
YSMFFFNFLFWVCGTLILGLAIWL O55158 10 10 -
YLLLGFNLLFWLAGSAVIAFGLWF O60636 13 13 -
YFLFLFNLLFFILGAVILGFGVWI O70352 11 11 -
YFLFLFNLLFFILGAVILGFGVWI CD82_MOUSE 11 11 -
YLLFTYNCCFWLAGLAVMAVGIWT O89118 18 18 -
YLLFTYNCCFWLAGLAVMAVGIWT C151_HUMAN 18 18 -
YVLFFFNFLFWVCGCCILGFGIHL CD53_RAT 10 10 -
YLLFTYNCCFWLAGLAVMAVGIWT C151_MOUSE 18 18 -
YVLFIFNLLFWVCGCCILGFGIYF CD53_MOUSE 10 10 -
YVLFFFNLLFWICGCCILGFGIYL CD53_HUMAN 11 11 -
YMMFLFNLIFWLCGCGLLGVGIWL O75954 11 11 -
YLMFAFNLLFWLGGCGVLGVGIWL NAG2_HUMAN 11 11 -
TLLIIYSFVFWITGVILLAVGVWG O88429 12 12 -
TLLIIYSFVFWITGVILLAVGVWG A15_MOUSE 12 12 -
TLLIIYSFVFWITGVILLAVGVWG A15_HUMAN 12 12 -
TMMILFNLLIFLCGAALLAVGIWV O60635 9 9 -
TMMILFNLLIFLCGAALLAVGIWV O60745 9 9 -
FLLYVLLLAFCACAVGLIAVGVGA CD63_HUMAN 11 11 -
FLLYVLLLAFCACAVGLIAIGVAV CD63_RAT 11 11 -
FLLYVLLLAFCACAVGLIAVGVGA CD63_RABIT 11 11 -
FLLYVLLLAFCACAVGLIAIGVAV CD63_MOUSE 11 11 -
SVLLIYTFIFWITGVILLAVGIWG O70401 19 19 -
SVLLIYTFIFWITGVILLAVGIWG O43657 19 19 -
YFLFVFNLFFFVLGGLIFCFGTWI CD37_MOUSE 13 13 -
YFLFVFNLFFFVLGGLIFCFGTWI CD37_RAT 13 13 -
YFIFGFNVIFWFLGITFLGIGLWA O60746 17 17 -
YFLFVFNLFFFVLGSLIFCFGIWI CD37_HUMAN 13 13 -
SCVFVLNIICLLCSLVLIGAGAYV IM23_SCHMA 13 13 -
SCVFVLNIICLLCSLVLIGAGAYV IM23_SCHHA 13 13 -
IVTFLFNFAFWLSGVVVFGLGIWL Q19983 10 10 -
SCVFILNIICLLCSLVLIGAGAYV IM23_SCHJA 13 13 -
YSVFSFNVIFFLLGFGLLLFGVWA Q22495 40 40 -
TVLVFLNLIFWGAAGILCYVGAYV O60637 11 11 -
LLFFVINFFICIFGALICGFSLWA Q18177 10 10 -
NALCALNVVYMLVSLLLIGVAAWG SAS_HUMAN 11 11 -
YLVYSYVVLLALTGAAQIFLGTSL O76137 12 12 -
Motif 2 width=27
Element Seqn Id St Int Rpt
FYTGVYILIGAGALMMLVGFLGCCGAV CD9_FELCA 53 18 -
FYTGVYILIGAGALMMLVGFLGCCGAV CD9_CERAE 55 20 -
FYTGVYILIGAGALMMLVGFLGCCGAV CD9_HUMAN 55 20 -
FYTGVYILIGAGALMMLVGFLGCCGAV CD9_BOVIN 53 18 -
FYTGVYILIGAGALMMLVGFLGCCGAV CD9_MOUSE 53 18 -
FYTGVYILIGAGALMMLVGFLGCCGAV CD9_RAT 53 18 -
FYVGIYILIAVGAVMMFVGFLGCYGAI CD81_HUMAN 58 22 -
FYVGIYILIAVGAVMMFVGFLGCYGAI CD81_MOUSE 58 22 -
FYVGIYILIAVGAVMMFVGFLGCYGAI Q62745 58 22 -
SYVAVDILIAVGAIIMILGFLGCCGAI CO02_HUMAN 52 18 -
LRMGAYVFIGVGAVTMLMGFLGCIGAV CD82_HUMAN 52 17 -
PFIAVNILIAVGSIIMVLGFLGCCGAV O55158 52 18 -
FYVGLYVLVGAGALMMAVGFFGCCGPC O60636 55 18 -
LQVGAYVFIGVGAITMLMGFLGCIGAV O70352 52 17 -
LQVGAYVFIGVGAITIVMGFLGCIGAV CD82_MOUSE 52 17 -
YLATAYILVVAGVVVMVTGVLGCCATF O89118 57 15 -
YLATAYILVVAGTVVMVTGVLGCCATF C151_HUMAN 57 15 -
FLTLGNVLVIVGSIIMVVAFLGCMGSI CD53_RAT 48 14 -
YLATAYILVVAGVVVMVTGVLGCCATF C151_MOUSE 57 15 -
FLTLGNILVIVGSIIMVVAFLGCMGSI CD53_MOUSE 48 14 -
SLTLGNVFVIVGSIIMVVAFLGCMGSI CD53_HUMAN 49 14 -
SLSAANLVIAIGTIVMVTGFLGCLGAI O75954 50 15 -
SLSAANLLIITGAFVMAIGFVGCLGAI NAG2_HUMAN 50 15 -
STNAPYVLIGTGTTIVVFGLFGCFATC O88429 50 14 -
STNAPYVLIGTGTTIVVFGLFGCFATC A15_MOUSE 50 14 -
STNAPYVLIGTGTTIVVFGLFGCFATC A15_HUMAN 50 14 -
FVNVGYFLIAAGVVVFALGFLGCYGAK O60635 53 20 -
FVNVGYFLIAAGVVVFALGFLGCYGAK O60745 53 20 -
GSLLPVVIIAVGVFLFLVAFVGCCGAC CD63_HUMAN 49 14 -
GSLLPVVIIAVGAFLFLVAFVGCCGAC CD63_RAT 49 14 -
GSLLPVVIIAVGAFLFLVAFVGCCGTC CD63_RABIT 49 14 -
GSLLPVVIIAVGAFLFLVAFVGCCGAC CD63_MOUSE 49 14 -
ATNVPFVLIGTGTVIILLGTFGCFATC O70401 57 14 -
ATNVPFVLIATGTVIILLGTFGCFATC O43657 57 14 -
LQTWSKVLAVSGVLTMALALLGCVGAL CD37_MOUSE 54 17 -
LQTWSKVLSVSGVLTMALALLGCVGAL CD37_RAT 54 17 -
GFDPVWLFLVVGGVMFILGFAGCIGAL O60746 58 17 -
LQIWSKVLAISGIFTMGIALLGCVGAL CD37_HUMAN 54 17 -
WQAAPIAIIVVGVIILIVSFLGCCGAI IM23_SCHMA 51 14 -
WQAAPIAIIVVGVIILIVSFLGCCGAI IM23_SCHHA 51 14 -
FRYVGWFLVGAGAIIILVGYFGCIGAW Q19983 53 19 -
WQAAPIAIIVVGVVILIVSFLGCCGAI IM23_SCHJA 51 14 -
YLDPTWPLLIVGFLTFIIGFSGCVGSL Q22495 81 17 -
TLIPAVVIIAVGALLFIIGLIGCCATI O60637 50 15 -
YQASLWILVAVGALLFLVGFFGCCGAG Q18177 64 30 -
SIHIIGGVIAVGVFLLLIAVAGLVGAV SAS_HUMAN 42 7 -
LWAPAAILLCLGPVTFILCWMGCQATN O76137 50 14 -
Motif 3 width=29
Element Seqn Id St Int Rpt
QESQCMLGLFFGFLLVIFAIEIAAAIWGY CD9_FELCA 80 0 -
QESQCMLGLFFGFLLVIFAIEIAAAIWGY CD9_CERAE 82 0 -
QESQCMLGLFFGFLLVIFAIEIAAAIWGY CD9_HUMAN 82 0 -
QESQCMLGLFFSFLLVIFAIEVAAAIWGY CD9_BOVIN 80 0 -
QESQCMLGLFFGFLLVIFAIEIAAAVWGY CD9_MOUSE 80 0 -
QESQCMLGLFFGFLLVIFAIEIAAAVWGY CD9_RAT 80 0 -
QESQCLLGTFFTCLVILFACEVAAGIWGF CD81_HUMAN 85 0 -
QESQCLLGTFFTCLVILFACEVAAGIWGF CD81_MOUSE 85 0 -
QESQCLLGTFFTCLVILFACEVAAGIWGF Q62745 85 0 -
KESRCMLLLFFIGLLLILLLQVATGILGA CO02_HUMAN 79 0 -
NEVRCLLGLYFAFLLLILIAQVTAGALFY CD82_HUMAN 79 0 -
KESRCMLLLFFIGLLLILLLQVAAGILGA O55158 79 0 -
WESQCVLGSFFTCLLVIFAAEVTTGVFAF O60636 82 0 -
NEVRCLLGLYFVFLLLILIAQVTVEVLFY O70352 79 0 -
NEVRCLLGLYFVFLLLILIAQVTVGVLFY CD82_MOUSE 79 0 -
KERRNLLRLYFILLLIIFLLEIIAGILAY O89118 84 0 -
KERRNLLRLYFILLLIIFLLEIIAGILAY C151_HUMAN 84 0 -
KENKCLLMSFFVLLLLILLAEVTLAILLF CD53_RAT 75 0 -
KERRNLLRLYFILLLIIFLLEIIAGILAY C151_MOUSE 84 0 -
KENKCLLMSFFVLLLIILLAEVTIAILLF CD53_MOUSE 75 0 -
KENKCLLMSFFILLLIILLAEVTLAILLF CD53_HUMAN 76 0 -
KENKCLLLSFFIVLLVILLAELILLILFF O75954 77 0 -
KENKCLLLTFFLLLLLVFLLEATIAILFF NAG2_HUMAN 77 0 -
RGSPWMLKLYAMFLSLVFLAELVAGISGF O88429 77 0 -
RGSPWMLKLYAMFLSLVFLAELVAGISGF A15_MOUSE 77 0 -
RGSPWMLKLYAMFLSLVFLAELVAGISGF A15_HUMAN 77 0 -
TESKCALVTFFFILLLIFIAEVAAAVVAL O60635 80 0 -
TESKCALVTFFFILLLIFIAEVAAAVVAL O60745 80 0 -
KENYCLMITFAIFLSLIMLVEVAAAIAGY CD63_HUMAN 76 0 -
KENYCLMITFAIFLSLIMLVEVAVAIAGY CD63_RAT 76 0 -
KENYCLMITFAIFLSLIMLVEVAAAIAGY CD63_RABIT 76 0 -
KENYCLMITFAIFLSLIMLVEVAVAIAGY CD63_MOUSE 76 0 -
RTSAWMLKLYAMFLTLIFLVELVAAIVGF O70401 84 0 -
RASAWMLKLYAMFLTLVFLVELVAAIVGF O43657 84 0 -
KELRCLLGLYFGMLLLLFATQITLGILIS CD37_MOUSE 81 0 -
KELRCLLGLYFGMLLLLFATQITLGILIS CD37_RAT 81 0 -
RENTFLLKFFSVFLGIIFFLELTAGVLAF O60746 85 0 -
KELRCLLGLYFGMLLLLFATQITLGILIS CD37_HUMAN 81 0 -
KENVCMLYMYAFFLVVLLIAELAAAIVAV IM23_SCHMA 78 0 -
KENVCMLYMYAFFLIILLIAELAAAIVAV IM23_SCHHA 78 0 -
KMNQCALAFFCCILILAFFLELAAAVTLF Q19983 80 0 -
KENVCMLYMYAFFLIVLLIAELVAAIVAV IM23_SCHJA 78 0 -
RENTSFLTFYSTLLGLLLIAEFSAGVFAY Q22495 108 0 -
RESRCGLATFVIILLLVFVTEVVVVVLGY O60637 77 0 -
CESPVLLGLFIFIIVILTAVELGATVFAM Q18177 91 0 -
NHHQVLLFFYMIILGLVFIFQFVISCSCL SAS_HUMAN 69 0 -
QRKRCLLGMFAALLVACICVQFIICGWSL O76137 77 0 -
Motif 4 width=27
Element Seqn Id St Int Rpt
IIGAVGIGIAVVMIFGMIFSMILCCAI CD9_FELCA 192 83 -
IIGAVGIGIAVVMIFGMIFSMILCCAI CD9_CERAE 194 83 -
IIGAVGIGIAVVMIFGMIFSMILCCAI CD9_HUMAN 194 83 -
IIGAVGIGIAVVMIFGMVFSMILCCAI CD9_BOVIN 192 83 -
IIGAVGIGIAVVMIFGMIFSMILCCAI CD9_MOUSE 192 83 -
IIGAVGIGIAVVMIFGMIFSMILCCAI CD9_RAT 192 83 -
LIGIAAIVVAVIMIFEMILSMVLCCGI CD81_HUMAN 204 90 -
LIGIAAIVVAVIMIFEMILSMVLCCGI CD81_MOUSE 204 90 -
LIGIAAIVVAVIMIFEMILSMVLCCGI Q62745 204 90 -
IVIGISFGLAVIEILGLVFSMVLYCQI CO02_HUMAN 208 100 -
IILGVGVGVAIIELLGMVLSICLCRHV CD82_HUMAN 230 122 -
IVIGIAFGLAVIEILGLVFSMVLYCQI O55158 206 98 -
LIGIVGIGIAGLTIFGMIFSMVLCCAI O60636 189 78 -
ILLGVCAGVAVIELLGLFLSICLCRYI O70352 229 121 -
ILLGVCAGVAVIELLGLFLSICLCRYI CD82_MOUSE 229 121 -
VIGAVGIGIACVQVFGMIFTCCLYRSL O89118 222 109 -
VIGAVGIGIACVQVFGMIFTCCLYRSL C151_HUMAN 222 109 -
YIGIVTICVCVIQVLGMSFALTLNCQI CD53_RAT 183 79 -
VIGAVGIGIACVQVFSMIFTCCLYRSL C151_MOUSE 222 109 -
YIGIITICVCVIQVLGMSFALTLNCQI CD53_MOUSE 183 79 -
YIGIITICVCVIEVLGMSFALTLNCQI CD53_HUMAN 184 79 -
VLGTVGMCILIMQILGMAFSMTLFQHI O75954 204 98 -
AVGIFGLCTALVQILGLTFAMTMYCQV NAG2_HUMAN 204 98 -
IIAGVAFGIAFSQLIGMLLACCLSRFI O88429 210 104 -
IIAGVAFGIAFSQLIGMLLACCLSRFI A15_MOUSE 210 104 -
IIAGVAFGIAFSQLIGMLLACCLSRFI A15_HUMAN 210 104 -
TVGGVAAGIGGLELAAMIVSMYLYCNL O60635 214 105 -
TVGGVAAGIGGLELAAMIVSMYLYCNL O60745 214 105 -
VVAAAALGIAFVEVLGIVFACCLVKSI CD63_HUMAN 204 99 -
LVAGAALGIAFVEVLGIIFSCCLVKSI CD63_RAT 204 99 -
VVAAAALGIAFVEVLGIVFACCLVKSI CD63_RABIT 204 99 -
LVAAAALGIAFVEVLGIIFSCCLVKSI CD63_MOUSE 204 99 -
VVAGISFGVACFQLIGIFLAYCLSRAI O70401 211 98 -
VVAGISFGVACFQLIGIFLAYCLSRAI O43657 211 98 -
SIVGICLGVGLLELGFMTLSIFLCRNL CD37_MOUSE 244 134 -
SIVGICLGVGLLELGFMTLSIFLCRNL CD37_RAT 244 134 -
IVAGIFIGIALLQIFGICLAQNLVSDI O60746 235 121 -
SIVGICLGVGLLELGFMTLSIFLCRNL CD37_HUMAN 244 134 -
IVACVAFGVCFFQLLSIVIACCLGRQI IM23_SCHMA 186 79 -
IVACVAFGVCFFQLLSIVIACCLGRQI IM23_SCHHA 186 79 -
LIVGVCVVLCIVQLLGIVLSMTLCCCK Q19983 251 142 -
IVACVAFGVCFFQLLSIVIACCLGQRI IM23_SCHJA 186 79 -
LVAVSMVIIAIIQVLGICFAQNLKSDI Q22495 271 134 -
HVIWAALAFAAIQLLGMLCACIVLCRR O60637 211 105 -
SIVVVAFLLLAIELFAILFSCILCRSS Q18177 197 77 -
ILGGVGLFFSFTEILGVWLAMRFRNQK SAS_HUMAN 174 76 -
ITAFGAAIIAIFQSLGIFCAVHLTILF O76137 202 96 -
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