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DAGPEDOMAIN  [View Relations]  [View Alignment]  

PR00008

4

05-APR-1991  (UPDATE 14-JUN-1999)

Diacylglycerol/phorbol-ester binding signature

PROSITE; PS00479 DAG_PE_BINDING_DOMAIN
BLOCKS; BL00479
PFAM; PF00130 DAG_PE-bind
INTERPRO; IPR002219

1. KIKKAWA, U., KISHIMOTO, A. AND NISHIZUKA, Y. 
The protein kinase C family: heterogeneity and its implications.
ANNU.REV.BIOCHEMISTRY 58 31-44 (1989). 
 
2. ONO, Y., FUJII, T., IGARASHI, K., TANAKA, C., KIKKAWA, U. 
AND NISHIZUKA, Y. 
Phorbol ester binding to protein kinase C requires a cysteine
zinc-finger-like sequence.
PROC.NATL.ACAD.SCI.U.S.A. 86 4868-4871 (1989).
 
3. BOGUSKI, M.S., BAIROCH, A., ATTWOOD, T.K. AND MICHAELS, G.S.
Proto-vav and gene expression.
NATURE 358 113 (1992).

Diacylglycerol (DAG) is an important second messenger; phorbol esters
(PE) are analogues of DAG and are potent tumour promoters that cause
a variety of physiological changes when administered to both cells and
tissues. DAG activates a family of Ser/Thr protein kinases known 
collectively as protein kinase C (PKC) [1]: PE's can stimulate PKC 
directly. The N-terminal region of PKC, known as C1, has been shown to 
bind PE and DAG in a phospholipid-dependent fashion [2]. The C1 region 
of PKC contains 1 or 2 copies of a Cys-rich region of about 50 amino acid 
residues, which is essential for DAG/PE binding.
 
DAGPEDOMAIN is a 4-element fingerprint that encodes this Cys-rich region. 
The fingerprint was derived from an initial alignment of 13 sequences 
(A.Bairoch, personal communication): the motifs span the full length of
the DAG/PE binding domain. Two iterations on OWL10.0 were required to
reach convergence, at which point every known occurrence of the motif was
detected (38 in all), together with an additional protein - the human vav
oncogene. The implication is that the vav oncogene may well bind DAG
and/or PE's and could thus be involved in signal transduction [3]. 
 
An update on SPTR37_9f identified a true set of 101 sequences, and 25
partial matches.

 101 codes involving  4 elements
  10 codes involving  3 elements
  13 codes involving  2 elements

CHIN_HUMAN    CHIN_RAT      CHIO_HUMAN    CHIO_RAT      
KDGA_HUMAN    KDGA_PIG      KDGA_RAT      KDGB_RAT      
KDGD_HUMAN    KDGG_HUMAN    KDGG_RAT      KDGL_CAEEL    
KMIL_CHICK    KPC1_CAEEL    KPC1_DROME    KPC1_HUMAN    
KPC1_RABIT    KPC1_RAT      KPC2_BOVIN    KPC2_CAEEL    
KPC2_DROME    KPC2_HUMAN    KPC2_MOUSE    KPC2_RABIT    
KPC3_DROME    KPCA_BOVIN    KPCA_HUMAN    KPCA_MOUSE    
KPCA_RABIT    KPCA_RAT      KPCD_HUMAN    KPCD_MOUSE    
KPCD_RAT      KPCE_HUMAN    KPCE_MOUSE    KPCE_RABIT    
KPCE_RAT      KPCG_HUMAN    KPCG_MOUSE    KPCG_RABIT    
KPCI_HUMAN    KPCL_HUMAN    KPCL_MOUSE    KPCL_RAT      
KPCM_HUMAN    KPCT_HUMAN    KPCT_MOUSE    KPCZ_HUMAN    
KPCZ_MOUSE    KPCZ_RABIT    KPCZ_RAT      KRAA_HUMAN    
KRAA_PIG      KRAA_RAT      KRAB_HUMAN    KRAF_HUMAN    
KRAF_RAT      KRAF_XENLA    O01583        O01715        
O14795        O17665        O44368        O44588        
O44590        O45720        O45818        O54874        
O54875        O61224        O61225        O62567        
O62569        O76664        O76850        O88469        
P90980        P90981        Q15144        Q15207        
Q16975        Q17860        Q19025        Q19266        
Q19770        Q20953        Q25378        Q62074        
Q62101        Q62768        Q62769        Q62770        
Q91569        Q92153        RMIL_CHICK    RMIL_COTJA    
UN13_CAEEL    VAV_HUMAN     VAV_MOUSE     VAV_RAT       
YB65_SCHPO    

CHIN_HUMAN  N-CHIMAERIN (NC) (N-CHIMERIN) (ALPHA CHIMERIN) (A-CHIMAERIN) - HOMO SAPIENS (HUMAN). 
CHIN_RAT    N-CHIMAERIN (NC) (N-CHIMERIN) (ALPHA CHIMERIN) (A-CHIMAERIN) - RATTUS NORVEGICUS (RAT). 
CHIO_HUMAN  BETA-CHIMAERIN (BETA-CHIMERIN) - HOMO SAPIENS (HUMAN). 
CHIO_RAT    BETA-CHIMAERIN (BETA-CHIMERIN) - RATTUS NORVEGICUS (RAT). 
KDGA_HUMAN  DIACYLGLYCEROL KINASE, ALPHA (EC 2.7.1.107) (DIGLYCERIDE KINASE) (DGK- ALPHA) (DAG KINASE ALPHA) (80 KD DIACYLGLYCEROL KINASE) - HOMO SAPIENS (HUMAN). 
KDGA_PIG    DIACYLGLYCEROL KINASE, ALPHA (EC 2.7.1.107) (DIGLYCERIDE KINASE) (DGK- ALPHA) (DAG KINASE ALPHA) (80 KD DIACYLGLYCEROL KINASE) - SUS SCROFA (PIG). 
KDGA_RAT    DIACYLGLYCEROL KINASE, ALPHA (EC 2.7.1.107) (DIGLYCERIDE KINASE) (DGK- ALPHA) (DAG KINASE ALPHA) (80 KD DIACYLGLYCEROL KINASE) - RATTUS NORVEGICUS (RAT). 
KDGB_RAT    DIACYLGLYCEROL KINASE, BETA (EC 2.7.1.107) (DIGLYCERIDE KINASE) (DGK- BETA) (DAG KINASE BETA) (90 KD DIACYLGLYCEROL KINASE) - RATTUS NORVEGICUS (RAT). 
KDGD_HUMAN  DIACYLGLYCEROL KINASE, DELTA (EC 2.7.1.107) (DIGLYCERIDE KINASE) (DGK- DELTA) (DAG KINASE DELTA) (80 KD DIACYLGLYCEROL KINASE) - HOMO SAPIENS (HUMAN). 
KDGG_HUMAN  DIACYLGLYCEROL KINASE, GAMMA (EC 2.7.1.107) (DIGLYCERIDE KINASE) (DGK- GAMMA) (DAG KINASE GAMMA) - HOMO SAPIENS (HUMAN). 
KDGG_RAT    DIACYLGLYCEROL KINASE, GAMMA (EC 2.7.1.107) (DIGLYCERIDE KINASE) (DGK- GAMMA) (DAG KINASE GAMMA) (88 KD DIACYLGLYCEROL KINASE) - RATTUS NORVEGICUS (RAT). 
KDGL_CAEEL  PROBABLE DIACYLGLYCEROL KINASE (EC 2.7.1.107) (DIGLYCERIDE KINASE) (DGK) (DAG KINASE) - CAENORHABDITIS ELEGANS. 
KMIL_CHICK  MIL PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE (EC 2.7.1.-) - GALLUS GALLUS (CHICKEN). 
KPC1_CAEEL  PROTEIN KINASE C-LIKE 1 (EC 2.7.1.-) (PKC) - CAENORHABDITIS ELEGANS. 
KPC1_DROME  PROTEIN KINASE C, BRAIN ISOZYME (EC 2.7.1.-) (PKC) (DPKC53E(BR)) - DROSOPHILA MELANOGASTER (FRUIT FLY). 
KPC1_HUMAN  PROTEIN KINASE C, BETA-I TYPE (EC 2.7.1.-) (PKC-BETA-1) - HOMO SAPIENS (HUMAN). 
KPC1_RABIT  PROTEIN KINASE C, BETA-I TYPE (EC 2.7.1.-) (PKC-BETA-1) - ORYCTOLAGUS CUNICULUS (RABBIT). 
KPC1_RAT    PROTEIN KINASE C, BETA-I TYPE (EC 2.7.1.-) (PKC-BETA-1) - RATTUS NORVEGICUS (RAT). 
KPC2_BOVIN  PROTEIN KINASE C, BETA-II TYPE (EC 2.7.1.-) (PKC-BETA-2) - BOS TAURUS (BOVINE). 
KPC2_CAEEL  PROTEIN KINASE C-LIKE 2 (EC 2.7.1.-) (PKC1B) - CAENORHABDITIS ELEGANS. 
KPC2_DROME  PROTEIN KINASE C, EYE ISOZYME (EC 2.7.1.-) (PKC) (DPKC53E(EY)) (PROTEIN INAC) (PHOTORECEPTOR-SPECIFIC PKC) (EYE-PKC) - DROSOPHILA MELANOGASTER (FRUIT FLY). 
KPC2_HUMAN  PROTEIN KINASE C, BETA-II TYPE (EC 2.7.1.-) (PKC-BETA-2) - HOMO SAPIENS (HUMAN). 
KPC2_MOUSE  PROTEIN KINASE C, BETA-II TYPE (EC 2.7.1.-) (PKC-BETA-2) - MUS MUSCULUS (MOUSE), AND RATTUS NORVEGICUS (RAT). 
KPC2_RABIT  PROTEIN KINASE C, BETA-II TYPE (EC 2.7.1.-) (PKC-BETA-2) - ORYCTOLAGUS CUNICULUS (RABBIT). 
KPC3_DROME  PROTEIN KINASE C (EC 2.7.1.-) (PKC) (DPKC98F) - DROSOPHILA MELANOGASTER (FRUIT FLY). 
KPCA_BOVIN  PROTEIN KINASE C, ALPHA TYPE (EC 2.7.1.-) (PKC-ALPHA) - BOS TAURUS (BOVINE). 
KPCA_HUMAN  PROTEIN KINASE C, ALPHA TYPE (EC 2.7.1.-) (PKC-ALPHA) - HOMO SAPIENS (HUMAN). 
KPCA_MOUSE  PROTEIN KINASE C, ALPHA TYPE (EC 2.7.1.-) (PKC-ALPHA) - MUS MUSCULUS (MOUSE). 
KPCA_RABIT  PROTEIN KINASE C, ALPHA TYPE (EC 2.7.1.-) (PKC-ALPHA) - ORYCTOLAGUS CUNICULUS (RABBIT). 
KPCA_RAT    PROTEIN KINASE C, ALPHA TYPE (EC 2.7.1.-) (PKC-ALPHA) - RATTUS NORVEGICUS (RAT). 
KPCD_HUMAN  PROTEIN KINASE C, DELTA TYPE (EC 2.7.1.-) (NPKC-DELTA) - HOMO SAPIENS (HUMAN). 
KPCD_MOUSE  PROTEIN KINASE C, DELTA TYPE (EC 2.7.1.-) (NPKC-DELTA) - MUS MUSCULUS (MOUSE). 
KPCD_RAT    PROTEIN KINASE C, DELTA TYPE (EC 2.7.1.-) (NPKC-DELTA) - RATTUS NORVEGICUS (RAT). 
KPCE_HUMAN  PROTEIN KINASE C, EPSILON TYPE (EC 2.7.1.-) (NPKC-EPSILON) - HOMO SAPIENS (HUMAN). 
KPCE_MOUSE  PROTEIN KINASE C, EPSILON TYPE (EC 2.7.1.-) (NPKC-EPSILON) - MUS MUSCULUS (MOUSE). 
KPCE_RABIT  PROTEIN KINASE C, EPSILON TYPE (EC 2.7.1.-) (NPKC-EPSILON) - ORYCTOLAGUS CUNICULUS (RABBIT). 
KPCE_RAT    PROTEIN KINASE C, EPSILON TYPE (EC 2.7.1.-) (NPKC-EPSILON) - RATTUS NORVEGICUS (RAT). 
KPCG_HUMAN  PROTEIN KINASE C, GAMMA TYPE (EC 2.7.1.-) (PKC-GAMMA) - HOMO SAPIENS (HUMAN). 
KPCG_MOUSE  PROTEIN KINASE C, GAMMA TYPE (EC 2.7.1.-) (PKC-GAMMA) - MUS MUSCULUS (MOUSE), AND RATTUS NORVEGICUS (RAT). 
KPCG_RABIT  PROTEIN KINASE C, GAMMA TYPE (EC 2.7.1.-) (PKC-GAMMA) (DELTA) - ORYCTOLAGUS CUNICULUS (RABBIT). 
KPCI_HUMAN  PROTEIN KINASE C, IOTA TYPE (EC 2.7.1.-) (NPKC-IOTA) - HOMO SAPIENS (HUMAN). 
KPCL_HUMAN  PROTEIN KINASE C, ETA TYPE (EC 2.7.1.-) (NPKC-ETA) (PKC-L) - HOMO SAPIENS (HUMAN). 
KPCL_MOUSE  PROTEIN KINASE C, ETA TYPE (EC 2.7.1.-) (NPKC-ETA) (PKC-L) - MUS MUSCULUS (MOUSE). 
KPCL_RAT    PROTEIN KINASE C, ETA TYPE (EC 2.7.1.-) (NPKC-ETA) (PKC-L) - RATTUS NORVEGICUS (RAT). 
KPCM_HUMAN  PROTEIN KINASE C, MU TYPE (EC 2.7.1.-) (NPKC-MU) - HOMO SAPIENS (HUMAN). 
KPCT_HUMAN  PROTEIN KINASE C, THETA TYPE (EC 2.7.1.-) (NPKC-THETA) - HOMO SAPIENS (HUMAN). 
KPCT_MOUSE  PROTEIN KINASE C, THETA TYPE (EC 2.7.1.-) (NPKC-THETA) - MUS MUSCULUS (MOUSE). 
KPCZ_HUMAN  PROTEIN KINASE C, ZETA TYPE (EC 2.7.1.-) (NPKC-ZETA) - HOMO SAPIENS (HUMAN). 
KPCZ_MOUSE  PROTEIN KINASE C, ZETA TYPE (EC 2.7.1.-) (NPKC-ZETA) - MUS MUSCULUS (MOUSE). 
KPCZ_RABIT  PROTEIN KINASE C, ZETA TYPE (EC 2.7.1.-) (NPKC-ZETA) - ORYCTOLAGUS CUNICULUS (RABBIT). 
KPCZ_RAT    PROTEIN KINASE C, ZETA TYPE (EC 2.7.1.-) (NPKC-ZETA) - RATTUS NORVEGICUS (RAT). 
KRAA_HUMAN  A-RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE (EC 2.7.1.-) (ONCOGENE PKS2) - HOMO SAPIENS (HUMAN). 
KRAA_PIG    A-RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE (EC 2.7.1.-) (A-RAF-1) - SUS SCROFA (PIG). 
KRAA_RAT    A-RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE (EC 2.7.1.-) - RATTUS NORVEGICUS (RAT). 
KRAB_HUMAN  B-RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE (EC 2.7.1.-) (P94) - HOMO SAPIENS (HUMAN). 
KRAF_HUMAN  RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE (EC 2.7.1.-) (RAF-1) (C-RAF) - HOMO SAPIENS (HUMAN). 
KRAF_RAT    RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE (EC 2.7.1.-) (RAF-1) (C-RAF) - RATTUS NORVEGICUS (RAT). 
KRAF_XENLA  RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE (EC 2.7.1.-) - XENOPUS LAEVIS (AFRICAN CLAWED FROG). 
O01583      SIMILAR TO SERINE/THREONINE-PROTEIN KINASE - CAENORHABDITIS ELEGANS. 
O01715      PROTEIN KINASE C - HYDRA ATTENUATA (HYDRA) (HYDRA VULGARIS). 
O14795      MUNC13 - HOMO SAPIENS (HUMAN).                
O17665      UNC-13 PROTEIN - CAENORHABDITIS ELEGANS.      
O44368      GENGHIS KHAN - DROSOPHILA MELANOGASTER (FRUIT FLY). 
O44588      F48G7.9 PROTEIN - CAENORHABDITIS ELEGANS.     
O44590      F48G7.10 PROTEIN - CAENORHABDITIS ELEGANS.    
O45720      R12G8.1 PROTEIN - CAENORHABDITIS ELEGANS.     
O45818      T25E12.4A PROTEIN - CAENORHABDITIS ELEGANS.   
O54874      MYTONIC DYSTROPHY KINASE-RELATED CDC42-BINDING KINASE - RATTUS NORVEGICUS (RAT). 
O54875      MYOTONIC DYSTROPHY KINASE-RELATED CDC42-BINDING KINASE MRCK-BETA - RATTUS NORVEGICUS (RAT). 
O61224      SERINE/THREONINE PROTEIN KINASE - SYCON RAPHANUS. 
O61225      SERINE/THREONINE PROTEIN KINASE - SYCON RAPHANUS. 
O62567      SERINE/THREONINE PROTEIN KINASE - SUBERITES DOMUNCULA. 
O62569      SERINE/THREONINE PROTEIN KINASE - SUBERITES DOMUNCULA. 
O76664      ALTERNATIVELY SPLICED FORM OF C. ELEGANS PROTEIN KINASE C-LIKE TPA-1 (SW: P34722) - CAENORHABDITIS ELEGANS. 
O76850      EYE-SPECIFIC PROTEIN KINASE C - CALLIPHORA VICINA (BLUE BLOWFLY) (CALLIPHORA ERYTHROCEPHALA). 
O88469      RAS GUANYL RELEASING PROTEIN - RATTUS NORVEGICUS (RAT). 
P90980      PROTEIN KINASE C2 A ISOFORM - CAENORHABDITIS ELEGANS. 
P90981      PROTEIN KINASE C2 B ISOFORM - CAENORHABDITIS ELEGANS. 
Q15144      PROTEIN KINASE C DELTA-TYPE - HOMO SAPIENS (HUMAN). 
Q15207      PROTEIN KINASE C, ZETA TYPE (EC 2.7.1.-) (NPKC-ZETA) - HOMO SAPIENS (HUMAN). 
Q16975      CALCIUM-INDEPENDENT PROTEIN KINASE C (EC 2.7.1.-) (APL II) - APLYSIA CALIFORNICA (CALIFORNIA SEA HARE). 
Q17860      DIACYLGLYCEROL KINASE - CAENORHABDITIS ELEGANS. 
Q19025      SIMILAR TO PROTEIN KINASE C - CAENORHABDITIS ELEGANS. 
Q19266      SIMILAR TO PROTEIN KINASE C - CAENORHABDITIS ELEGANS. 
Q19770      F25B3.3 PROTEIN - CAENORHABDITIS ELEGANS.     
Q20953      KIN-13 PROTEIN - CAENORHABDITIS ELEGANS.      
Q25378      PROTEIN KINASE C (EC 2.7.1.-) - LYTECHINUS PICTUS (PAINTED SEA URCHIN). 
Q62074      PROTEIN KINASE C, IOTA TYPE (EC 2.7.1.-) (NPKC-IOTA) (PROTEIN KINASE C LAMBDA) - MUS MUSCULUS (MOUSE). 
Q62101      PROTEIN KINASE C, MU (SERINE/THREONINE PROTEIN KINASE) - MUS MUSCULUS (MOUSE). 
Q62768      MUNC13-1 - RATTUS NORVEGICUS (RAT).           
Q62769      MUNC13-2 - RATTUS NORVEGICUS (RAT).           
Q62770      MUNC13-3 - RATTUS NORVEGICUS (RAT).           
Q91569      PROTEIN KINASE C SUBSPECIES LAMBDA/IOTA - XENOPUS LAEVIS (AFRICAN CLAWED FROG). 
Q92153      HAT-2 - SERINUS CANARIA (CANARY).             
RMIL_CHICK  RMIL SERINE/THREONINE-PROTEIN KINASE (EC 2.7.1.-) - GALLUS GALLUS (CHICKEN). 
RMIL_COTJA  RMIL SERINE/THREONINE-PROTEIN KINASE (EC 2.7.1.-) - COTURNIX COTURNIX JAPONICA (JAPANESE QUAIL). 
UN13_CAEEL  PHORBOL ESTER/DIACYLGLYCEROL-BINDING PROTEIN UNC-13 - CAENORHABDITIS ELEGANS. 
VAV_HUMAN   VAV PROTO-ONCOGENE - HOMO SAPIENS (HUMAN).    
VAV_MOUSE   VAV PROTO-ONCOGENE - MUS MUSCULUS (MOUSE).    
VAV_RAT     VAV PROTO-ONCOGENE (P95) - RATTUS NORVEGICUS (RAT). 
YB65_SCHPO  HYPOTHETICAL 72.2 KD PROTEIN C12C2.05C IN CHROMOSOME II - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST). 
 
KPC1_ASPNG  PROTEIN KINASE C-LIKE (EC 2.7.1.-) - ASPERGILLUS NIGER. 
KPC1_TRIRE  PROTEIN KINASE C-LIKE (EC 2.7.1.-) - TRICHODERMA REESEI (HYPOCREA JECORINA). 
KPC1_YEAST  PROTEIN KINASE C-LIKE 1 (EC 2.7.1.-) (PKC 1) - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST). 
O00538      F25B3.3 KINASE LIKE PROTEIN - HOMO SAPIENS (HUMAN). 
O88673      DIACYLGLYCEROL KINASE, ALPHA (EC 2.7.1.107) (DIGLYCERIDE KINASE) (DGK- ALPHA) (DAG KINASE ALPHA) (80 KD DIACYLGLYCEROL KINASE) - MUS MUSCULUS (MOUSE). 
P87253      PROTEIN KINASE C-LIKE (EC 2.7.1.-) - NEUROSPORA CRASSA. 
PCK2_SCHPO  PROTEIN KINASE C-LIKE 2 (EC 2.7.1.-) - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST). 
Q22744      T24F1.3 PROTEIN - CAENORHABDITIS ELEGANS.     
VAV2_HUMAN  VAV2 PROTEIN - HOMO SAPIENS (HUMAN).          
VAV2_MOUSE  VAV2 PROTEIN - MUS MUSCULUS (MOUSE).          
 
KDGH_HUMAN  PUTATIVE DIACYLGLYCEROL KINASE ETA (EC 2.7.1.107) (DIGLYCERIDE KINASE) (DGK-ETA) (DAG KINASE ETA) (DIACYLGLYCEROL KINASE, DELTA) (KIAA0145) - HOMO SAPIENS (HUMAN). 
KDGH_MESAU  DIACYLGLYCEROL KINASE ETA (EC 2.7.1.107) (DIGLYCERIDE KINASE) (DGK- ETA) (DAG KINASE ETA) - MESOCRICETUS AURATUS (GOLDEN HAMSTER). 
KPC1_CANAL  PROTEIN KINASE C-LIKE 1 (EC 2.7.1.-) (PKC 1) - CANDIDA ALBICANS (YEAST). 
KRAF_CAEEL  RAF HOMOLOG SERINE/THREONINE-PROTEIN KINASE (EC 2.7.1.-) - CAENORHABDITIS ELEGANS. 
KRAF_DROME  RAF HOMOLOG SERINE/THREONINE-PROTEIN KINASE DRAF-1 (EC 2.7.1.-) (POLE-HOLE PROTEIN) - DROSOPHILA MELANOGASTER (FRUIT FLY). 
O01738      SIMILARITY TO PROTEIN KINASE C - CAENORHABDITIS ELEGANS. 
O15463      PTPL1-ASSOCIATED RHOGAP - HOMO SAPIENS (HUMAN). 
O42632      PROTEIN KINASE C-LIKE (EC 2.7.1.-) - COCHLIOBOLUS HETEROSTROPHUS (DRECHSLERA MAYDIS). 
O44113      PUTATIVE GUANINE NUCLEOTIDE EXCHANGE FACTOR RHOGEF2 - DROSOPHILA MELANOGASTER (FRUIT FLY). 
O44381      SHAR PEI/DRHOGEF2 - DROSOPHILA MELANOGASTER (FRUIT FLY). 
P97306      STAC - MUS MUSCULUS (MOUSE).                  
PCK1_SCHPO  PROTEIN KINASE C-LIKE 1 (EC 2.7.1.-) - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST). 
Q99469      STAC - HOMO SAPIENS (HUMAN).                  

OWL10_0    2  85   NSINGLE    
OWL17_1    1  210  NSINGLE    
OWL18_0    1  280  NSINGLE    
OWL19_1    1  250  NSINGLE    
OWL26_0    1  500  NSINGLE    
SPTR37_9f  4  350  NSINGLE    

Motif 1  width=15
Element                        Seqn Id          St    Int   Rpt 
EKIHNFKVHTFRGPH                CHIN_HUMAN       43     43     - 
VKSHKFTARFFKQPT                KPCG_BOVIN       18     18     - 
VKNHRFIARFFKQPT                KIBOC            34     34     - 
LTMHNFVRKTFFSLA                TVHUAF           96     96     - 
LTTHNFARKTFLKLA                TVHUF6          136    136     - 
HIKHQIIRKTFFSLV                DRORAFPO        147    147     - 
NGQHMWRPKRFPRPV                S09156          202    202     - 
RSKHKFKIHTYGSPT                KPCA_RAT         99     99     - 
VKNHKFTARFFKQPT                KIRTC1           34     34     - 
VNGHKFMATYLRQPT                KPCE_MOUSE      167    167     - 
IKNHEFIATFFGQPT                KPCD_RAT        156    156     - 
VNGHRFGVRFFKNPT                KPC2_DROME       69     69     - 
ANGHLFQAKRFNRRA                KPCZ_RAT         28     28     - 
 
Motif 2  width=10
Element                        Seqn Id          St    Int   Rpt 
CDHCGTLLWG                     KPCD_RAT        244     73     - 
CDHCGSLLYG                     KPCA_RAT        115      1     - 
CSHCTDFIWG                     KPCG_BOVIN       34      1     - 
CSHCTDFIWG                     KIBOC            50      1     - 
CDFCLKFLFH                     TVHUAF          112      1     - 
CDICQKFLLN                     TVHUF6          152      1     - 
CEGCRRLLFT                     DRORAFPO        163      1     - 
CDRCQKKIRI                     S09156          281     64     - 
CSHCTDFIWG                     KIRTC1           50      1     - 
CEYCANFMWG                     CHIN_HUMAN       59      1     - 
CGQCSERIWG                     KPCZ_RAT         44      1     - 
CGHCKDFIWG                     KPC2_DROME       85      1     - 
CDHCGSLLWG                     KPCE_MOUSE      256     74     - 
 
Motif 3  width=12
Element                        Seqn Id          St    Int   Rpt 
QGVKCADCGLNV                   CHIN_HUMAN       72      3     - 
QGFQCQVCCFVV                   KIRTC1           63      3     - 
QGLQCQVCSFVV                   KPCG_BOVIN       47      3     - 
QGFQCQVCCFVV                   KIBOC            63      3     - 
HGFRCQTCGYKF                   TVHUAF          121     -1     - 
NGFRCQTCGYKF                   TVHUF6          161     -1     - 
TGFYCSQCNFRF                   DRORAFPO        172     -1     - 
VGLHCVWCHLEI                   S09156          295      4     - 
QGMKCDTCDMNV                   KPCA_RAT        128      3     - 
QGLQCKVCKMNV                   KPCE_MOUSE      269      3     - 
QGLKCEDCGMNV                   KPCD_RAT        257      3     - 
QGVKCENCNLNV                   KPC2_DROME      163     68     - 
QGYRCINCKLLV                   KPCZ_RAT         57      3     - 
 
Motif 4  width=13
Element                        Seqn Id          St    Int   Rpt 
HRRCVRSVPSLCG                  KPCG_BOVIN      124     65     - 
HRRCETNVAPNCG                  KPCE_MOUSE      281      0     - 
HHKCREKVANLCG                  KPCD_RAT        269      0     - 
HHACQETVPPMCG                  KPC2_DROME      175      0     - 
HKRCHVLVPLTCR                  KPCZ_RAT         69      0     - 
HKQCSKMVPNDCK                  CHIN_HUMAN       84      0     - 
HKRCVMNVPSLCG                  KIRTC1          140     65     - 
HKQCVINVPSLCG                  KPCA_RAT        140      0     - 
HDDCLPAMGHECD                  S09156          307      0     - 
HQRCANRVPMLCQ                  DRORAFPO        184      0     - 
HEHCSTKVPTMCV                  TVHUF6          173      0     - 
HQHCSSKVPTVCV                  TVHUAF          133      0     - 
HKRCHEFVTFSCP                  KIBOC            75      0     - 

Motif 1  width=15
Element                        Seqn Id          St    Int   Rpt 
VKNHKFTARFFKQPT                KPC2_RABIT       34     34     - 
VKNHKFTARFFKQPT                KPC2_MOUSE       34     34     - 
VKNHKFTARFFKQPT                KPC2_HUMAN       34     34     - 
VKNHKFTARFFKQPT                KPC2_BOVIN       34     34     - 
VKNHKFTARFFKQPT                KPC1_RAT         34     34     - 
VKNHKFTARFFKQPT                KPC1_RABIT       34     34     - 
VKNHKFTARFFKQPT                KPC1_HUMAN       34     34     - 
RSKHKFKIHTYGSPT                KPCA_RAT         99     99     - 
VKDHKFIARFFKQPT                KPCA_RABIT       34     34     - 
VKDHKFIARFFKQPT                KPCA_HUMAN       34     34     - 
VKNHRFIARFFKQPT                KPCA_BOVIN       34     34     - 
IKSHKFIARFFKQPT                P90980           36     36     - 
IKSHKFIARFFKQPT                Q19025          101    101     - 
IKSHKFIARFFKQPT                P90981           36     36     - 
VKSHKFTARFFKQPT                KPCG_MOUSE       33     33     - 
VKSHKFTARFFKQPT                KPCG_HUMAN       33     33     - 
VKSHKFTARFFKQPT                KPCG_RABIT       33     33     - 
VKDHCFIARFFKQPT                KPC1_DROME       43     43     - 
IKNHKFIPRFFKQPT                Q25378           25     25     - 
VKDHKFIARFFKQPT                KPCA_MOUSE       34     34     - 
VNGHKFMAMFFRQPT                Q16975          174    174     - 
VNGHKFMATFLRQPT                KPC3_DROME       69     69     - 
VNGHKFMATYLRQPT                KPCE_HUMAN      167    167     - 
VNGHKFMATYLRQPT                KPCE_MOUSE      167    167     - 
VNGHKFMATYLRQPT                KPCE_RABIT      167    167     - 
VNGHKFMATYLRQPT                KPCE_RAT        167    167     - 
VNGHKFMATYLRQPT                KPCL_MOUSE      169    169     - 
VNGHKFMATYLRQPT                KPCL_RAT        169    169     - 
VTGHKFMALFLRQPT                Q20953            8      8     - 
INGHKFMATYLRQPT                KPCL_HUMAN      168    168     - 
VNGHKFVVRFFKQPT                O76850           54     54     - 
VRDHEFEPRFFKQPT                O61224           41     41     - 
VTGHKFMALFLRHAT                KPC2_CAEEL      168    168     - 
VKCHEFTATFFPQPT                KPCT_HUMAN      157    157     - 
VKCHEFTATFFPQPT                KPCT_MOUSE      157    157     - 
IKNHEFIATFFGQPT                KPCD_HUMAN      156    156     - 
IKNHEFIATFFGQPT                KPCD_MOUSE      156    156     - 
IKNHEFIATFFGQPT                Q15144          106    106     - 
IKNHEFIATFFGQPT                KPCD_RAT        156    156     - 
VNGHRFGVRFFKNPT                KPC2_DROME       69     69     - 
IRGHKFVLNYFKQFT                O62567           24     24     - 
INGHGYKARFFRQPT                O61225          184    184     - 
VKDHKFVPKFFTSPT                O01715           28     28     - 
IRGHQFVATFFRQPH                KPC1_CAEEL      163    163     - 
IRGHQFVATFFRQPH                O76664           56     56     - 
FKGHMFIKKFFRRPT                O62569          175    175     - 
ANGHLFQAKRFNRRA                Q15207          128    128     - 
ANGHLFQAKRFNRRA                KPCZ_RABIT      128    128     - 
ANGHLFQAKRFNRRA                KPCZ_HUMAN      120    120     - 
ISGHKFKAVGLAQPT                O45720           24     24     - 
ANGHLFQAKRFNRRA                KPCZ_RAT         28     28     - 
ANGHTFQAKRFNRRA                Q91569          131    131     - 
ANGHTFQAKRFNRRA                Q62074          129    129     - 
ANGHTFQAKRFNRRA                KPCI_HUMAN      129    129     - 
ANGHLFQAKRFNRGA                KPCZ_MOUSE      128    128     - 
EKTHNFKVHTFRGPH                CHIO_RAT         39     39     - 
EKTHNFKVHTFRGPH                CHIO_HUMAN      212    212     - 
EKVHNFKVHTFRGPH                Q92153           43     43     - 
EKVHNFKVHTFRGPH                CHIN_RAT         78     78     - 
EKIHNFKVHTFRGPH                CHIN_HUMAN       43     43     - 
GFKHNFHETTFLTPT                Q19770          518    518     - 
GFPHNFQETTYLKPT                O88469          539    539     - 
KVPHTFVIHSYTRPT                Q62101          274    274     - 
YNGHRFQAKRLNRRI                Q19266          125    125     - 
KVPHTFVIHSYTRPT                KPCM_HUMAN      268    268     - 
ISGHRFKATALVQPT                O44590           24     24     - 
TTPHNFATTTFQTPT                O17665          690    690     - 
TTPHNFATTTFQTPT                UN13_CAEEL      693    693     - 
LTTHNFVRKTFFTLA                KRAB_HUMAN      231    231     - 
LTTHNFVRKTFFTLA                RMIL_COTJA      232    232     - 
LTTHNFVRKTFFTLA                RMIL_CHICK      232    232     - 
GRFHDFKHVSFKLPT                YB65_SCHPO      395    395     - 
VAGHKFRAAALLQPT                O44588           24     24     - 
QVPHTFQVHSYKLPT                O45818          471    471     - 
TAIHQFLVRTFSSPT                O44368          963    963     - 
NHGHYFVKKTFGKPA                Q17860           18     18     - 
PKAHQFSIKSFPSPT                O54875         1024   1024     - 
LTTHNFARKTFLKLA                KRAF_RAT        136    136     - 
LTTHNFARKTFLKLA                KRAF_HUMAN      136    136     - 
LTTHNFARKTFLKLA                KMIL_CHICK      136    136     - 
TTPHNFEVWTATTPT                O14795          475    475     - 
TTPHNFEVWTATTPT                Q62768          564    564     - 
RKTHQFFVKSFTAPT                O54874         1010   1010     - 
APGHSFRKVTLTKPT                KDGD_HUMAN       58     58     - 
TTPHNFEVWSATTPT                Q62769          851    851     - 
LTMHNFVRKTFFSLA                KRAA_HUMAN       96     96     - 
LTMHNFVRKTFFSLA                KRAA_PIG         96     96     - 
LTMHNFVRKTFFSLA                KRAA_RAT         96     96     - 
TTPHNFEVWTATTPT                Q62770         1088   1088     - 
ERGHNFERMKIKTPT                O01583          953    953     - 
DGGHAWTMKHFKKPT                KDGG_HUMAN      269    269     - 
DGRHAWTLKHFKKPT                KDGG_RAT        266    266     - 
LTTHNFVRKTFLKLA                KRAF_XENLA      135    135     - 
DGSHVWRLRHFTKPT                KDGL_CAEEL      278    278     - 
ANGHDFQMFSFEETT                VAV_RAT         513    513     - 
ANGHDFQMFSFEETT                VAV_MOUSE       513    513     - 
ANGHDFQMFSFEETT                VAV_HUMAN       513    513     - 
DGQHVWRLKHFNKPA                KDGB_RAT        241    241     - 
DGHHIWRPKRFSRPV                KDGA_RAT        201    201     - 
DGQHMWRPKRFPRPV                KDGA_HUMAN      203    203     - 
NGQHMWRPKRFPRPV                KDGA_PIG        202    202     - 
 
Motif 2  width=10
Element                        Seqn Id          St    Int   Rpt 
CSHCTDFIWG                     KPC2_RABIT       50      1     - 
CSHCTDFIWG                     KPC2_MOUSE       50      1     - 
CSHCTDFIWG                     KPC2_HUMAN       50      1     - 
CSHCTDFIWG                     KPC2_BOVIN       50      1     - 
CSHCTDFIWG                     KPC1_RAT         50      1     - 
CSHCTDFIWG                     KPC1_RABIT       50      1     - 
CSHCTDFIWG                     KPC1_HUMAN       50      1     - 
CDHCGSLLYG                     KPCA_RAT        115      1     - 
CSHCTDFIWG                     KPCA_RABIT       50      1     - 
CSHCTDFIWG                     KPCA_HUMAN       50      1     - 
CSHCTDFIWG                     KPCA_BOVIN       50      1     - 
CSHCKDFLWG                     P90980           52      1     - 
CSHCKDFLWG                     Q19025          117      1     - 
CSHCKDFLWG                     P90981           52      1     - 
CSHCTDFIWG                     KPCG_MOUSE       49      1     - 
CSHCTDFIWG                     KPCG_HUMAN       49      1     - 
CSHCTDFIWG                     KPCG_RABIT       49      1     - 
CSHCKDFIWG                     KPC1_DROME       59      1     - 
CSHCKDFIWG                     Q25378           41      1     - 
CSHCTDFIWG                     KPCA_MOUSE       50      1     - 
CSLCRDFIWG                     Q16975          190      1     - 
CSHCREFIWG                     KPC3_DROME       85      1     - 
CSHCRDFIWG                     KPCE_HUMAN      183      1     - 
CDHCGSLLWG                     KPCE_MOUSE      256     74     - 
CSHCRDFIWG                     KPCE_RABIT      183      1     - 
CSHCRDFIWG                     KPCE_RAT        183      1     - 
CSHCREFIWG                     KPCL_MOUSE      185      1     - 
CSHCREFIWG                     KPCL_RAT        185      1     - 
CAHCKEFIWG                     Q20953           24      1     - 
CSHCREFIWG                     KPCL_HUMAN      184      1     - 
CGHCKDFIWG                     O76850           70      1     - 
CAHCKEFIWG                     O61224           57      1     - 
CAHCKEFIWG                     KPC2_CAEEL      184      1     - 
CEHCGTLLWG                     KPCT_HUMAN      245     73     - 
CEHCGTLLWG                     KPCT_MOUSE      245     73     - 
CDHCGSLLWG                     KPCD_HUMAN      244     73     - 
CDHCGSLLWG                     KPCD_MOUSE      244     73     - 
CDHCGSLLWG                     Q15144          194     73     - 
CDHCGTLLWG                     KPCD_RAT        244     73     - 
CGHCKDFIWG                     KPC2_DROME       85      1     - 
CGHCTRFLWG                     O62567           40      1     - 
CGFCKEFLWG                     O61225          200      1     - 
CAHCKDFIWG                     O01715           44      1     - 
CSLCSDFMWG                     KPC1_CAEEL      179      1     - 
CSLCSDFMWG                     O76664           72      1     - 
CSLCREFLWG                     O62569          191      1     - 
CGQCSERIWG                     Q15207          144      1     - 
CGQCSERIWG                     KPCZ_RABIT      144      1     - 
CGQCSERIWG                     KPCZ_HUMAN      136      1     - 
CSFCSKFIYG                     O45720           40      1     - 
CGQCSERIWG                     KPCZ_RAT         44      1     - 
CAICTDRIWG                     Q91569          147      1     - 
CAICTDRIWG                     Q62074          145      1     - 
CAICTDRIWG                     KPCI_HUMAN      145      1     - 
CGQCSERIWG                     KPCZ_MOUSE      144      1     - 
CEYCANFMWG                     CHIO_RAT         55      1     - 
CEYCANFMWG                     CHIO_HUMAN      228      1     - 
CEYCANFMWG                     Q92153           59      1     - 
CEYCANFMWG                     CHIN_RAT         94      1     - 
CEYCANFMWG                     CHIN_HUMAN       59      1     - 
CNHCNKLLWG                     Q19770          534      1     - 
CDNCAGFLWG                     O88469          555      1     - 
CQFCKKLLKG                     Q62101          290      1     - 
CFICHDYIWG                     Q19266          141      1     - 
CQYCKKLLKG                     KPCM_HUMAN      284      1     - 
CDHCGSLLYG                     O44590          127     88     - 
CYECEGLLWG                     O17665          706      1     - 
CYECEGLLWG                     UN13_CAEEL      709      1     - 
CDFCRKLLFQ                     KRAB_HUMAN      247      1     - 
CDFCRKLLFQ                     RMIL_COTJA      248      1     - 
CDFCRKLLFQ                     RMIL_CHICK      248      1     - 
CSYCREIIWG                     YB65_SCHPO      411      1     - 
CAFCSKIIYG                     O44588           40      1     - 
CQHCKKLLKG                     O45818          487      1     - 
CNHCTSLMVG                     O44368          979      1     - 
CHHCCDKIWG                     Q17860           34      1     - 
CSHCTSLMVG                     O54875         1040      1     - 
CDICQKFLLN                     KRAF_RAT        152      1     - 
CDICQKFLLN                     KRAF_HUMAN      152      1     - 
CDICQKFLLN                     KMIL_CHICK      152      1     - 
CYECEGLLWG                     O14795          491      1     - 
CYECEGLLWG                     Q62768          580      1     - 
CHQCTSLMVG                     O54874         1026      1     - 
CHLCSDFIWG                     KDGD_HUMAN       74      1     - 
CYECEGLLWG                     Q62769          867      1     - 
CDFCLKFLFH                     KRAA_HUMAN      112      1     - 
CDFCLKFLFH                     KRAA_PIG        112      1     - 
CDFCLKFLFH                     KRAA_RAT        112      1     - 
CYECEGLLWG                     Q62770         1104      1     - 
CGHCTSILIG                     O01583          969      1     - 
CNFCHIMLMG                     KDGG_HUMAN      285      1     - 
CNFCHIMLMG                     KDGG_RAT        282      1     - 
CDICQKFLLN                     KRAF_XENLA      151      1     - 
CNACCSILVG                     KDGL_CAEEL      294      1     - 
CKACQMLLRG                     VAV_RAT         529      1     - 
CKACQMLLRG                     VAV_MOUSE       529      1     - 
CKACQMLLRG                     VAV_HUMAN       529      1     - 
CNLCLNMLIG                     KDGB_RAT        257      1     - 
CDRCQKKIRT                     KDGA_RAT        280     64     - 
CDRCQKKIRI                     KDGA_HUMAN      282     64     - 
CDRCQKKIRI                     KDGA_PIG        281     64     - 
 
Motif 3  width=12
Element                        Seqn Id          St    Int   Rpt 
QGFQCQVCCFVV                   KPC2_RABIT       63      3     - 
QGFQCQVCCFVV                   KPC2_MOUSE       63      3     - 
QGFQCQVCCFVV                   KPC2_HUMAN       63      3     - 
QGFQCQVCCFVV                   KPC2_BOVIN       63      3     - 
QGFQCQVCCFVV                   KPC1_RAT         63      3     - 
QGFQCQVCCFVV                   KPC1_RABIT       63      3     - 
QGFQCQVCCFVV                   KPC1_HUMAN       63      3     - 
QGMKCDTCDMNV                   KPCA_RAT        128      3     - 
QGFQCQVCCFVV                   KPCA_RABIT       63      3     - 
QGFQCQVCCFVV                   KPCA_HUMAN       63      3     - 
QGFQCQVCCFVV                   KPCA_BOVIN       63      3     - 
QGFQCQVCTLVV                   P90980           65      3     - 
QGFQCQVCTLVV                   Q19025          130      3     - 
QGFQCQVCTLVV                   P90981           65      3     - 
QGLQCQVCSFVV                   KPCG_MOUSE       62      3     - 
QGLQCQVCSFVV                   KPCG_HUMAN       62      3     - 
QGLQCQVCSFVV                   KPCG_RABIT       62      3     - 
QGFQCQVCSYVV                   KPC1_DROME       72      3     - 
QGFQCKVCSFVV                   Q25378           54      3     - 
QGFQCQVCCFVV                   KPCA_MOUSE       63      3     - 
QGYQCQVCTCVV                   Q16975          203      3     - 
QGYQCQVCTLVV                   KPC3_DROME       98      3     - 
QGYQCQVCTCVV                   KPCE_HUMAN      197      4     - 
QGLQCKVCKMNV                   KPCE_MOUSE      269      3     - 
QGYQCQVCTCVV                   KPCE_RABIT      197      4     - 
QGYQCQVCTCVV                   KPCE_RAT        197      4     - 
QGYQCQVCTCVV                   KPCL_MOUSE      199      4     - 
QGYQCQVCTCVV                   KPCL_RAT        199      4     - 
QGYQCQICTVVV                   Q20953           37      3     - 
QGYQCQVCTCVV                   KPCL_HUMAN      198      4     - 
QGVKCDNCNLNV                   O76850          148     68     - 
QGLKCQACEMNV                   O61224          133     66     - 
QGYQCQICTVVV                   KPC2_CAEEL      197      3     - 
QGLKCDACGMNV                   KPCT_HUMAN      258      3     - 
QGLKCDACGMNV                   KPCT_MOUSE      258      3     - 
QGLKCEDCGMNV                   KPCD_HUMAN      257      3     - 
QGLKCEDCGMNV                   KPCD_MOUSE      257      3     - 
QGLKCEDCGMNV                   Q15144          207      3     - 
QGLKCEDCGMNV                   KPCD_RAT        257      3     - 
QGVKCENCNLNV                   KPC2_DROME      163     68     - 
QGVQCSDCGINV                   O62567          117     67     - 
QGLQCEVCKANC                   O61225          292     82     - 
NGFQCKVCSFGV                   O01715           58      4     - 
QGYQCQLCSAAV                   KPC1_CAEEL      192      3     - 
QGYQCQLCSAAV                   O76664           85      3     - 
HGYQCQVCQYTS                   O62569          204      3     - 
QGYRCINCKLLV                   Q15207          157      3     - 
QGYRCINCKLLV                   KPCZ_RABIT      157      3     - 
QGYRCINCKLLV                   KPCZ_HUMAN      149      3     - 
QGVQCTDCHANV                   O45720          136     86     - 
QGYRCINCKLLV                   KPCZ_RAT         57      3     - 
QGYKCINCKLLV                   Q91569          160      3     - 
QGYKCINCKLLV                   Q62074          158      3     - 
QGYKCINCKLLV                   KPCI_HUMAN      158      3     - 
QGYRCINCKLLV                   KPCZ_MOUSE      157      3     - 
QGVRCSDCGLNV                   CHIO_RAT         68      3     - 
QGVRCSDCGLNV                   CHIO_HUMAN      241      3     - 
QGVKCADCGLNV                   Q92153           72      3     - 
QGVKCADCGLNV                   CHIN_RAT        107      3     - 
QGVKCADCGLNV                   CHIN_HUMAN       72      3     - 
QGFKCKDCGLAV                   Q19770          547      3     - 
QGYRCKDCGMNC                   O88469          568      3     - 
QGLQCKDCRFNC                   Q62101          303      3     - 
QGFRCVDCRLCV                   Q19266          154      3     - 
QGLQCKDCRFNC                   KPCM_HUMAN      297      3     - 
QGVQCSDCLANV                   O44590          140      3     - 
QGLRCTQCQVKV                   O17665          719      3     - 
QGLRCTQCQVKV                   UN13_CAEEL      722      3     - 
QGFRCQTCGYKF                   KRAB_HUMAN      256     -1     - 
QGFRCQTCGYKF                   RMIL_COTJA      257     -1     - 
QGFRCQTCGYKF                   RMIL_CHICK      257     -1     - 
RGCVCKNCGFKC                   YB65_SCHPO      424      3     - 
QGYRCLGCETVV                   O44588           53      3     - 
QGMQCRDCKYNC                   O45818          500      3     - 
QGVVCEICGFAC                   O44368          992      3     - 
TGYSCEMCNFVC                   Q17860           47      3     - 
QGYACEVCAFSC                   O54875         1053      3     - 
NGFRCQTCGYKF                   KRAF_RAT        161     -1     - 
NGFRCQTCGYKF                   KRAF_HUMAN      161     -1     - 
NGFRCQTCGYKF                   KMIL_CHICK      161     -1     - 
QGMRCSECGVKC                   O14795          504      3     - 
QGMRCTECGVKC                   Q62768          593      3     - 
QGCSCEVCGFSC                   O54874         1039      3     - 
AGVRCEWCGVQA                   KDGD_HUMAN      211    127     - 
QGMRCSECGVKC                   Q62769          880      3     - 
HGFRCQTCGYKF                   KRAA_HUMAN      121     -1     - 
HGFRCQTCGYKF                   KRAA_PIG        121     -1     - 
HGFRCQTCGYKF                   KRAA_RAT        121     -1     - 
QGMKCLECGVKC                   Q62770         1117      3     - 
QGLFCQSCQYAC                   O01583          982      3     - 
QGLCCTYCKYTV                   KDGG_HUMAN      298      3     - 
QGLCCIYCKYAV                   KDGG_RAT        295      3     - 
NAFRCQTCGYKF                   KRAF_XENLA      160     -1     - 
QGLSCSLCKYTV                   KDGL_CAEEL      308      4     - 
QGYRCYRCRAPA                   VAV_RAT         542      3     - 
QGYRCYRCRAPA                   VAV_MOUSE       542      3     - 
QGYRCHRCRASA                   VAV_HUMAN       542      3     - 
QGLCCSFCKYTV                   KDGB_RAT        270      3     - 
TGLHCVWCHLEI                   KDGA_RAT        294      4     - 
TGLHCVWCHLEI                   KDGA_HUMAN      296      4     - 
VGLHCVWCHLEI                   KDGA_PIG        295      4     - 
 
Motif 4  width=13
Element                        Seqn Id          St    Int   Rpt 
HKRCVMNVPSLCG                  KPC2_RABIT      140     65     - 
HKRCVMNVPSLCG                  KPC2_MOUSE      140     65     - 
HKRCVMNVPSLCG                  KPC2_HUMAN      140     65     - 
HKRCVMNVPSLCG                  KPC2_BOVIN      140     65     - 
HKRCVMNVPSLCG                  KPC1_RAT        140     65     - 
HKRCVMNVPSLCG                  KPC1_RABIT      140     65     - 
HKRCVMNVPSLCG                  KPC1_HUMAN      140     65     - 
HKQCVINVPSLCG                  KPCA_RAT        140      0     - 
HKQCVINVPSLCG                  KPCA_RABIT      140     65     - 
HKQCVINVPSLCG                  KPCA_HUMAN      140     65     - 
HKQCVINVPSLCG                  KPCA_BOVIN      140     65     - 
HHRCVKNVPNMCG                  P90980          142     65     - 
HHRCVKNVPNMCG                  Q19025          207     65     - 
HHRCVKNVPNMCG                  P90981          142     65     - 
HRRCVRSVPSLCG                  KPCG_MOUSE      139     65     - 
HRRCVRSVPSLCG                  KPCG_HUMAN      139     65     - 
HRRCVRTVPSLCG                  KPCG_RABIT      139     65     - 
HARCKENVPSLCG                  KPC1_DROME      149     65     - 
HKRCQKSVPNLCG                  Q25378          131     65     - 
HKQCVINDPSLCG                  KPCA_MOUSE      140     65     - 
HKRCQKNVANNCG                  Q16975          286     71     - 
HKRCQKNVANTCG                  KPC3_DROME      185     75     - 
HRRCETNVAPNCG                  KPCE_HUMAN      281     72     - 
HRRCETNVAPNCG                  KPCE_MOUSE      281      0     - 
HRRCETNVAPNCG                  KPCE_RABIT      281     72     - 
HRRCETNVAPNCG                  KPCE_RAT        281     72     - 
HIRCQANVAPNCG                  KPCL_MOUSE      284     73     - 
HIRCQANVAPNCG                  KPCL_RAT        284     73     - 
HKRCQRNVANNCG                  Q20953          127     78     - 
HIRCQANVAPNCG                  KPCL_HUMAN      283     73     - 
HHGCKDKVPPLCG                  O76850          160      0     - 
HKRCERFVPQLCG                  O61224          145      0     - 
HKRCQRNVANNCG                  KPC2_CAEEL      287     78     - 
HHRCQTKVANLCG                  KPCT_HUMAN      270      0     - 
HHRCQTKVANLCG                  KPCT_MOUSE      270      0     - 
HHKCREKVANLCG                  KPCD_HUMAN      269      0     - 
HHKCREKVANLCG                  KPCD_MOUSE      269      0     - 
HHKCREKVANLCG                  Q15144          219      0     - 
HHKCREKVANLCG                  KPCD_RAT        269      0     - 
HHACQETVPPMCG                  KPC2_DROME      175      0     - 
HHRCKGLVPKTCG                  O62567          129      0     - 
HKRCQGSMPNLCG                  O61225          304      0     - 
HKRCHEYVSFKCP                  O01715           70      0     - 
HHKCERLMSNLCG                  KPC1_CAEEL      276     72     - 
HHKCERLMSNLCG                  O76664          169     72     - 
HTKCAQNMPPLCG                  O62569          288     72     - 
HKRCHGLVPLTCR                  Q15207          169      0     - 
HKRCHGLVPLTCR                  KPCZ_RABIT      169      0     - 
HKRCHGLVPLTCR                  KPCZ_HUMAN      161      0     - 
HFRCQEKVLRNCG                  O45720          148      0     - 
HKRCHVLVPLTCR                  KPCZ_RAT         69      0     - 
HKKCHKLVTIECG                  Q91569          172      0     - 
HKKCHKLVTIECG                  Q62074          170      0     - 
HKKCHKLVTIECG                  KPCI_HUMAN      170      0     - 
HKRCHVLVPLTCR                  KPCZ_MOUSE      169      0     - 
HKQCSKHVPNDCQ                  CHIO_RAT         80      0     - 
HKQCSKHVPNDCQ                  CHIO_HUMAN      253      0     - 
HKQCSKMVPNDCK                  Q92153           84      0     - 
HKQCSKMVPNDCK                  CHIN_RAT        119      0     - 
HKQCSKMVPNDCK                  CHIN_HUMAN       84      0     - 
HSCCKSNAVAECR                  Q19770          559      0     - 
HKQCKDLVVFECK                  O88469          580      0     - 
HKRCAPKVPNNCL                  Q62101          315      0     - 
HKKCHRHVRTHCG                  Q19266          166      0     - 
HKRCAPKVPNNCL                  KPCM_HUMAN      309      0     - 
HHRCKEKAVHNCI                  O44590          152      0     - 
HDKCRELLSADCL                  O17665          731      0     - 
HDKCRELLSADCL                  UN13_CAEEL      734      0     - 
HQRCSTEVPLMCV                  KRAB_HUMAN      268      0     - 
HQRCSTEVPLMCV                  RMIL_COTJA      269      0     - 
HQRCSTEVPLMCV                  RMIL_CHICK      269      0     - 
HARCELLVPANCK                  YB65_SCHPO      436      0     - 
HKKCHASMITCCV                  O44588           65      0     - 
HKKCSEHVAKDCS                  O45818          512      0     - 
HTICCQKVPTTCP                  O44368         1004      0     - 
HEKCLRTVVSYCS                  Q17860           59      0     - 
HVSCKDSAPQVCP                  O54875         1065      0     - 
HEHCSTKVPTMCV                  KRAF_RAT        173      0     - 
HEHCSTKVPTMCV                  KRAF_HUMAN      173      0     - 
HEHCSTKVPTMCV                  KMIL_CHICK      173      0     - 
HEKCQDLLNADCL                  O14795          516      0     - 
HEKCQDLLNADCL                  Q62768          605      0     - 
HITCVNKAPTTCP                  O54874         1051      0     - 
HSLCSAALAPECG                  KDGD_HUMAN      223      0     - 
HEKCQDLLNADCL                  Q62769          892      0     - 
HQHCSSKVPTVCV                  KRAA_HUMAN      133      0     - 
HQHCSSKVPTVCV                  KRAA_PIG        133      0     - 
HQHCSSKVPTVCV                  KRAA_RAT        133      0     - 
HEKCQDLLNADCL                  Q62770         1129      0     - 
HVSCAERVSQSCP                  O01583          994      0     - 
HERCVSKNIPGCV                  KDGG_HUMAN      310      0     - 
HQRCVSNSIPGCV                  KDGG_RAT        307      0     - 
HEHCSTKVPTMCV                  KRAF_XENLA      172      0     - 
HERCVRSAATNCI                  KDGL_CAEEL      320      0     - 
HKECLGRVPPCGR                  VAV_RAT         554      0     - 
HKECLGRVPPCGR                  VAV_MOUSE       554      0     - 
HKECLGRVPPCGR                  VAV_HUMAN       554      0     - 
HERCARAPPSCIK                  KDGB_RAT        282      0     - 
HDDCLQAVGPECD                  KDGA_RAT        306      0     - 
HDDCLQAVGHECD                  KDGA_HUMAN      308      0     - 
HDDCLPAMGHECD                  KDGA_PIG        307      0     -