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PR01736

Identifier
PHPHTRNFRASE  [View Relations]  [View Alignment]  
Accession
PR01736
No. of Motifs
4
Creation Date
28-JUN-2002
Title
Phosphoenolpyruvate-protein phosphotransferase signature 
Database References

PDB; 1ZYM
SCOP; 1ZYM
CATH; 1ZYM
Literature References
1. SAFFEN, D.W., PRESPER, K.A., DOERING, T.L. AND ROSEMAN, S.
Sugar transport by the bacterial phosphotransferase system. Molecular 
cloning and structural analysis of the Escherichia coli ptsH, ptsI, and err 
genes. 
J.BIOL.CHEM. 262 16241-16253 (1987).
 
2. GINSBURG, A. AND PETERKOFSY, A.
Enzyme I: the gataway to the bacterial phosphoenolpyruvate:sugar 
phosphotransferase system.
ARCH.BIOCHEM.BIOPHYS. 397 273-278 (2002).
 
3. HIGA, F. AND EDELSTEIN, P.H. 
Potential virulence role of the Legionella pneumophila ptsP ortholog.
INFECT.IMMUN. 69 4782-4789 (2001).
 
4. LIAO, D.I., SILVERTON, E., SEOK, Y.J., LEE, B.R., PETERKOFSY, A. AND 
DAVIES, D.R.
The first step in sugar transport: crystal structure of the amino terminal 
domain of enzyme I of the E.coli PEP:sugar phosphotransferase system and a 
model of the phospotransfer complex with HPr.
STRUCTURE 4 861-872 (1996).

Documentation
The phosphoenolpyruvate phosphotransferase (PEP-PTS) system of bacteria 
facilitates the utilisation of a number of small molecules via a complex 
two-component sensing and regulatory phosphate transfer system [1]. The 
system transports these moieties through the cell membrane and tightly 
couples transport with phosphoryl transfer from the PEP to the molecule
via several phosphoprotein intermediates [1]. Sugars are usually the 
molecules transferred, although translocation of proteins and nitrogen has
also been implicated [1]. 
 
The first step in the process is catalysed by PTS Enzyme 1, a protein with 
two functional domains [2]. Enzyme 1 dimerisation is required in order for  
autophosphorylation by PEP in the presence of MgCl2. While the N-terminal 
domain of Enzyme 1 matches the nitrogen-sensitive domain of some plant 
pathogens, the C-terminal domain is similar to other Enzyme 1 and phosphate
dikinase genes from some Archaea microbes [2]. Research suggests that the
protein serves a sensory function, joining carbon and nitrogen metabolism 
together in prokaryotic cells [2].
 
More recently, an in vitro/vivo study has demonstrated that the Legionella 
pneumophila Enzyme 1 ortholog (termed PtsP) is essential for its virulence 
[3]. Mutational studies conferred an avirulent state on pathogenic strains,
and comparison of the full PtsP ORF to P.aeruginosa Enzyme 1 confirmed that 
the protein was required for successful host infection [3]. The structure of
the N-terminal domain of Escherichia coli PEP-PTS Enzyme 1 has been resolved
to 2.5A using X-ray crystallography [4]. It contains two distinct subdomains,
one of which contains four alpha-helices, the other consisting of a beta-
sandwich. This domain is topologically similar to the pyruvate phosphate
dikinase enzyme of several other pathogenic bacteria [4].
 
PHPHTRNFRASE is a 4-element fingerprint that provides a signature for the
phosphoenolpyruvate-protein phosphotransferase family. The fingerprint was
derived from an initial alignment of 9 sequences: the motifs were drawn 
from conserved regions spanning the C-terminal portion of the alignment.
Three iterations on SPTR40_20f were required to reach convergence, at which
point a true set comprising 72 sequences was identified. Numerous partial 
matches were also found, all of which are bacterial PTS system proteins that
fail to match one or more motifs.
Summary Information
  72 codes involving  4 elements
3 codes involving 3 elements
17 codes involving 2 elements
Composite Feature Index
472727272
33330
241488
1234
True Positives
O87685        PT1P_ECOLI    PT1_ALCEU     PT1_BACHD     
PT1_BACME PT1_BACSP PT1_BACST PT1_BACSU
PT1_BORBU PT1_BUCAI PT1_ECOLI PT1_HAEIN
PT1_LACLA PT1_LACLC PT1_LACSK PT1_MYCCA
PT1_MYCGE PT1_MYCPN PT1_SALTY PT1_STAAU
PT1_STACA PT1_STRMU PT1_STRSL PTF1_RHOCA
PTF1_XANCP Q8VP40 Q8VP88 Q8X6K3
Q8XBL3 Q8XBQ8 Q8XHW9 Q8XQE5
Q8XVH0 Q8Y2I8 Q8YJ96 Q8Z411
Q8ZCJ2 Q8ZHU9 Q8ZIT3 Q92MK4
Q931U2 Q93MZ3 Q93TM5 Q97EM3
Q97QM7 Q98FU8 Q98G92 Q98PW7
Q99V14 Q99Z66 Q9A9W2 Q9AAQ9
Q9AAZ4 Q9AHU0 Q9CMD3 Q9EYJ0
Q9EYQ8 Q9EZA6 Q9HXN5 Q9HY55
Q9JWF8 Q9JXH7 Q9KJV2 Q9KTD7
Q9KU52 Q9KZP1 Q9PDH7 Q9RGC5
Q9RNG5 Q9WXK9 Q9X4P3 YPDD_ECOLI
True Positive Partials
Codes involving 3 elements
PT1A_ECOLI Q8X760 Q8ZKM7
Codes involving 2 elements
O85840 PODK_RHIME PPSA_AQUAE PPSA_ARCFU
PPSA_METJA PPSA_PYRAB PPSA_PYRFU PPSA_PYRHO
PT1_CHLMU PT1_CHLPN PT1_CHLTR Q8ZT84
Q97A04 Q9HJS8 Q9HSA1 Q9I2W9
Q9RI40
Sequence Titles
O87685      ENZYME I (EC 2.7.3.9) - Azotobacter vinelandii. 
PT1P_ECOLI Phosphoenolpyruvate-protein phosphotransferase ptsP (EC 2.7.3.9) (Phosphotransferase system, enzyme I) (Enzyme I-Ntr) - Escherichia coli.
PT1_ALCEU Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) (Protein I) - Alcaligenes eutrophus (Ralstonia eutropha).
PT1_BACHD Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Bacillus halodurans.
PT1_BACME Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Bacillus megaterium.
PT1_BACSP Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Bacillus sp. (strain S).
PT1_BACST Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Bacillus stearothermophilus.
PT1_BACSU Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Bacillus subtilis.
PT1_BORBU Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Borrelia burgdorferi (Lyme disease spirochete).
PT1_BUCAI Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Buchnera aphidicola (subsp. Acyrthosiphon pisum) (Acyrthosiphon pisum symbiotic bacterium).
PT1_ECOLI Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Escherichia coli.
PT1_HAEIN Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Haemophilus influenzae.
PT1_LACLA Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Lactococcus lactis (subsp. lactis) (Streptococcus lactis).
PT1_LACLC Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Lactococcus lactis (subsp. cremoris) (Streptococcus cremoris).
PT1_LACSK Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Lactobacillus sakei.
PT1_MYCCA Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Mycoplasma capricolum.
PT1_MYCGE Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Mycoplasma genitalium.
PT1_MYCPN Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Mycoplasma pneumoniae.
PT1_SALTY Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Salmonella typhimurium.
PT1_STAAU Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Staphylococcus aureus.
PT1_STACA Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Staphylococcus carnosus.
PT1_STRMU Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Streptococcus mutans.
PT1_STRSL Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Streptococcus salivarius.
PTF1_RHOCA Multiphosphoryl transfer protein (MTP) [Includes: Phosphoenolpyruvate- protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I); Phosphocarrier protein HPR (Protein H); PTS system, fructose-specific IIA component (EIIA-FRU) (Fructose-permease IIA component) (Phosphotransferase enzyme II, A component) (EC 2.7.1.69) (EIII-FRU)] - Rhodobacter capsulatus (Rhodopseudomonas capsulata).
PTF1_XANCP Multiphosphoryl transfer protein (MTP) [Includes: Phosphoenolpyruvate- protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I); Phosphocarrier protein HPR (Protein H); PTS system, fructose-specific IIA component (EIIA-FRU) (Fructose-permease IIA component) (Phosphotransferase enzyme II, A component) (EC 2.7.1.69) (EIII-FRU)] - Xanthomonas campestris (pv. campestris).
Q8VP40 PUTATIVE PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHORYLTRANSFERASE PPTE - Escherichia coli.
Q8VP88 ENZYME I - Streptococcus thermophilus.
Q8X6K3 PTS SYSTEM, ENZYME I, TRANSCRIPTIONAL REGULATOR (WITH NPR AND NTR PROTEINS) - Escherichia coli O157:H7.
Q8XBL3 PEP-PROTEIN PHOSPHOTRANSFERASE SYSTEM ENZYME I - Escherichia coli O157:H7.
Q8XBQ8 PUTATIVE PTS SYSTEM ENZYME IIA COMPONENT, ENZYME I - Escherichia coli O157:H7.
Q8XHW9 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE - Clostridium perfringens.
Q8XQE5 PROBABLE MULTIFUNCTIONAL PROTEIN : PHOSPHOCARRIER PROTEIN HPR (PROTEIN H) AND PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE (EC 2.7.3.9) - Ralstonia solanacearum (Pseudomonas solanacearum).
Q8XVH0 PROBABLE MULTIPHOSPHORYL TRANSFER PROTEIN MTP (EC 2.7.3.9) - Ralstonia solanacearum (Pseudomonas solanacearum).
Q8Y2I8 PROBABLE PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE TRANSMEMBRANE (EC 2.7.3.9) - Ralstonia solanacearum (Pseudomonas solanacearum).
Q8YJ96 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE PTSP (EC 2.7.3.9) - Brucella melitensis.
Q8Z411 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE - Salmonella typhi.
Q8ZCJ2 PTS SYTEM, ENZYME I COMPONENT (EC 2.7.3.9) - Yersinia pestis.
Q8ZHU9 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE (EC 2.7.3.9) - Yersinia pestis.
Q8ZIT3 PUTATIVE PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE (EC 2.7.3.9) - Yersinia pestis.
Q92MK4 PROBABLE PHOSPHOENOLPYRUVATE PHOSPHOTRANSFERASE PTSP (ENZYME I-NTR) PROTEIN (EC 2.7.3.9) - Rhizobium meliloti (Sinorhizobium meliloti).
Q931U2 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHATASE - Staphylococcus aureus (strain Mu50 / ATCC 700699).
Q93MZ3 PHOSPHOENOLPYRUVATE:SUGAR PHOSPHOTRANSFERASE SYSTEM ENZYME I - Corynebacterium glutamicum (Brevibacterium flavum).
Q93TM5 ENZYME I - Lactobacillus brevis.
Q97EM3 PHOSPHOENOLPYRUVATE-PROTEIN KINASE (PTS SYSTEM ENZYME I) - Clostridium acetobutylicum.
Q97QM7 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE - Streptococcus pneumoniae.
Q98FU8 PHOSPHOTRANSFERASE SYSTEM ENZYME I - Rhizobium loti (Mesorhizobium loti).
Q98G92 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE, PTSP - Rhizobium loti (Mesorhizobium loti).
Q98PW7 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE (PHOSPHOTRANSFERASE SYSTEM, ENZYME I) (EC 2.7.3.9) - Mycoplasma pulmonis.
Q99V14 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHATASE - Staphylococcus aureus (strain N315).
Q99Z66 PUTATIVE PHOSPHOENOLPYRUVATE:SUGAR PHOSPHOTRANSFERASE SYSTEM ENZYME I (EC 2.7.3.9) - Streptococcus pyogenes.
Q9A9W2 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE - Caulobacter crescentus.
Q9AAQ9 PTS SYSTEM, FRUCTOSE-SPECIFIC EIIA/HPR/EI COMPONENTS - Caulobacter crescentus.
Q9AAZ4 PTS SYSTEM, FRUCTOSE-SPECIFIC EIIA/HPR/EI COMPONENTS - Caulobacter crescentus.
Q9AHU0 PHOSPHOENOLPYRUVATE:SUGAR PHOSPHOTRANSFERASE SYSTEM ENZYME I - Lactococcus lactis (subsp. lactis) (Streptococcus lactis).
Q9CMD3 PTSI - Pasteurella multocida.
Q9EYJ0 ENZYMEI-NTR - Bradyrhizobium japonicum.
Q9EYQ8 ENZYME I - Staphylococcus xylosus.
Q9EZA6 PHOSPHOTRANSFERASE SYSTEM ENZYME I - Zymomonas mobilis.
Q9HXN5 PROBABLE PHOSPHOTRANSFERASE PROTEIN - Pseudomonas aeruginosa.
Q9HY55 PROBABLE PHOSPHOTRANSFERASE SYSTEM ENZYME I - Pseudomonas aeruginosa.
Q9JWF8 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE (EC 2.7.3.9) - Neisseria meningitidis (serogroup A).
Q9JXH7 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE - Neisseria meningitidis (serogroup B).
Q9KJV2 ENZYME I - Lactobacillus casei.
Q9KTD7 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE - Vibrio cholerae.
Q9KU52 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE - Vibrio cholerae.
Q9KZP1 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE - Streptomyces coelicolor.
Q9PDH7 PHOSPHOTRANSFERASE SYSTEM ENZYME I - Xylella fastidiosa.
Q9RGC5 ENZYME I - Mycoplasma hyopneumoniae.
Q9RNG5 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE PTSP - Legionella pneumophila.
Q9WXK9 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE - Streptococcus bovis.
Q9X4P3 PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE PTSP - Pseudomonas aeruginosa.
YPDD_ECOLI Putative phosphoenolpyruvate-protein phosphotransferase ypdD (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Escherichia coli.

PT1A_ECOLI Phosphoenolpyruvate-protein phosphotransferase ptsA (EC 2.7.3.9) (Phosphotransferase system, enzyme I) (Enzyme I-Ani) - Escherichia coli.
Q8X760 PEP-PROTEIN PHOSPHOTRANSFERASE SYSTEM ENZYME I - Escherichia coli O157:H7.
Q8ZKM7 GENERAL PTS FAMILY, ENZYME I (EC 2.7.3.9) - Salmonella typhimurium.

O85840 PYRUVATE PHOSPHATE DIKINASE - Sphingomonas aromaticivorans.
PODK_RHIME Pyruvate,phosphate dikinase (EC 2.7.9.1) (Pyruvate,orthophosphate dikinase) - Rhizobium meliloti (Sinorhizobium meliloti).
PPSA_AQUAE Phosphoenolpyruvate synthase (EC 2.7.9.2) (Pyruvate,water dikinase) (PEP synthase) - Aquifex aeolicus.
PPSA_ARCFU Probable phosphoenolpyruvate synthase (EC 2.7.9.2) (Pyruvate,water dikinase) (PEP synthase) - Archaeoglobus fulgidus.
PPSA_METJA Probable phosphoenolpyruvate synthase (EC 2.7.9.2) (Pyruvate,water dikinase) (PEP synthase) [Contains: Mja pep intein (Mja pepA intein)] - Methanococcus jannaschii.
PPSA_PYRAB Probable phosphoenolpyruvate synthase (EC 2.7.9.2) (Pyruvate,water dikinase) (PEP synthase) - Pyrococcus abyssi.
PPSA_PYRFU Probable phosphoenolpyruvate synthase (EC 2.7.9.2) (Pyruvate,water dikinase) (PEP synthase) - Pyrococcus furiosus.
PPSA_PYRHO Probable phosphoenolpyruvate synthase (EC 2.7.9.2) (Pyruvate,water dikinase) (PEP synthase) - Pyrococcus horikoshii.
PT1_CHLMU Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Chlamydia muridarum.
PT1_CHLPN Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Chlamydia pneumoniae (Chlamydophila pneumoniae).
PT1_CHLTR Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I) - Chlamydia trachomatis.
Q8ZT84 PYRUVATE, PHOSPHATE DIKINASE - Pyrobaculum aerophilum.
Q97A04 PYRUVATE ORTHOPHOSPHATE DIKINASE - Thermoplasma volcanium.
Q9HJS8 PROBABLE PYRUVATE ORTHOPHOSPHATE DIKINASE - Thermoplasma acidophilum.
Q9HSA1 PHOSPHOENOLPYRUVATE SYNTHASE - Halobacterium sp. (strain NRC-1).
Q9I2W9 PHOSPHOENOLPYRUVATE SYNTHASE - Pseudomonas aeruginosa.
Q9RI40 PYRUVATE PHOSPHATE DIKINASE - Streptomyces coelicolor.
Scan History
SPTR40_20f 3  100  NSINGLE    
Initial Motifs
Motif 1  width=20
Element Seqn Id St Int Rpt
GLYRTEFLYMDSQDFPTEDE PT1_STRMU 295 295 -
GLYRTEFLFMDRDALPTEEE Q9KTD7 293 293 -
GLYRTEIPFMLQSGFPSEEE Q8ZHU9 459 459 -
GLYRTEVPFMINDRFPSEKE Q9X4P3 467 467 -
GLYRTEVPFMNNERFPSEKE O87685 467 467 -
GLYRSEVPFMSRDRFPSEDE Q9RNG5 475 475 -
GLYRTEIPFMLQSGFPSEEE PT1P_ECOLI 459 459 -
GLYRTEIPFMLQSGFPSEEE Q8X6K3 459 459 -
GLYRTEISFLLQHRFPSEEE Q9KU52 459 459 -

Motif 2 width=16
Element Seqn Id St Int Rpt
DFFSIGTNDLIQYTMA PT1_STRMU 451 136 -
SFFSIGTNDLTQYTLA Q9KTD7 447 134 -
DFISVGTNDLTQYLLA Q8ZHU9 613 134 -
DFLSVGSNDLTQYLLA Q9X4P3 620 133 -
DFLSVGSNDLTQYLLA O87685 620 133 -
DFISVGSNDLTQYLLA Q9RNG5 628 133 -
DFISVGTNDLTQYILA PT1P_ECOLI 613 134 -
DFISVGTNDLTQYILA Q8X6K3 613 134 -
DFVSVGTNDLTQYLLA Q9KU52 612 133 -

Motif 3 width=16
Element Seqn Id St Int Rpt
DRMNEQVSYLYQPYNP PT1_STRMU 468 1 -
DRGNEMISHLYNPLSP Q9KTD7 464 1 -
DRNNTRVASLYDSLHP Q8ZHU9 630 1 -
DRNNPRVADLYDYLHP Q9X4P3 637 1 -
DRNNPRVADLYDYLHP O87685 637 1 -
DRNNARVAALYDPLHP Q9RNG5 645 1 -
DRNNTRVANIYDSLHP PT1P_ECOLI 630 1 -
DRNNTRVANIYDSLHP Q8X6K3 630 1 -
DRNNARVADVYESMHP Q9KU52 629 1 -

Motif 4 width=13
Element Seqn Id St Int Rpt
GMCGEMAGDQTAV PT1_STRMU 504 20 -
GMCGELAGDERAT Q9KTD7 500 20 -
SLCGEMAGDPMGA Q8ZHU9 666 20 -
SICGEMAGDPAAA Q9X4P3 673 20 -
SICGEMAGDPSAA O87685 673 20 -
SICGEMASDPLAV Q9RNG5 681 20 -
RLCGEMAGDPMCV PT1P_ECOLI 666 20 -
RLCGEMAGDPMCV Q8X6K3 666 20 -
CVCGELAGDPIGA Q9KU52 665 20 -
Final Motifs
Motif 1  width=20
Element Seqn Id St Int Rpt
GLYRTEFLYMDRDQLPTEEE PT1_BACHD 294 294 -
GLYRTEFLYMGREDLPTEEE PT1_BACME 294 294 -
GLYRTEFLYMGRDQLPTEDE PT1_BACSU 293 293 -
GLYRTEFLYMGRSELPTEDE PT1_BACSP 299 299 -
GLYRTEFLYMGRSELPTEDE PT1_BACST 299 299 -
GLYRTEFLYMDSQDFPTEDE PT1_STRMU 295 295 -
GLYRTEFLYMDSQDFPTEDE Q9WXK9 295 295 -
GLYRTEFLYMDSQDFPTEDE Q97QM7 295 295 -
GLYRTEFLYMDSQDFPTEDE Q99Z66 295 295 -
GLYRTEFLYMGRDQMPTEEE PT1_STAAU 295 295 -
GLYRTEFLYMGRDQMPTEEE Q99V14 295 295 -
GLYRTEFLYMGRDQMPTEEE Q931U2 295 295 -
GLYRTEFLYMDSQDFPTEED Q8VP88 295 295 -
GLFRTEFLYMDRDQMPTEDE Q97EM3 292 292 -
GLYRTEFLYMDSQDFPTEDD PT1_STRSL 295 295 -
GLYRTEFLYMDAQDFPTEDD PT1_LACLA 295 295 -
GLYRTEFLYMDAQDFPTEDD Q9AHU0 295 295 -
GLYRTEFLYMDAQDFPTEDD PT1_LACLC 295 295 -
GLYRTEFLYMGRDEMPTEDK Q9EYQ8 294 294 -
GLFRTEFLYMDRDEAPTEDE Q8XHW9 291 291 -
GLFRTEFLYMDNDHFPTEEE PT1_MYCCA 294 294 -
GLYRTEFLFMDREQLPTEEE PT1_HAEIN 293 293 -
GLYRTEFLFMDRDALPTEEE PT1_ECOLI 293 293 -
GLYRTEFLFMDRDALPTEEE Q8XBL3 293 293 -
GLYRTEFLFMDRDALPTEEE PT1_SALTY 293 293 -
GLYRTEFLFMDRDSLPTEEE Q8ZCJ2 293 293 -
GLYRTEFLFMDREQLPTEEE Q9CMD3 293 293 -
GLYRTEFLYMGRDQMPTEEE PT1_STACA 295 295 -
GLYRTEFLYMDSAELPSEDD PT1_LACSK 294 294 -
GLYRTEFLFMDRDALPTEEE Q9KTD7 293 293 -
GLYRTEFLYMDSAELPTEDD Q9KJV2 295 295 -
GLFRSEFLYMDRSNWPSEEE Q9RGC5 295 295 -
GLYRTEFLFMGRNCLPDENE PT1_BUCAI 293 293 -
GLFRTEFLYMNSQEWPDEET PT1_MYCPN 294 294 -
GLFRSEFLYMDNSNWPSEEE Q98PW7 289 289 -
GLMRTEFLYMDAERVPTEDE Q93TM5 292 292 -
GLFRTEFLYMSSQDWPDESV PT1_MYCGE 294 294 -
GLYRTEIPFMLQSGFPSEEE Q8ZHU9 459 459 -
GLYRTEVPFMINDRFPSEKE Q9X4P3 467 467 -
GLYRTEVPFMNNERFPSEKE O87685 467 467 -
GLYRSEVPFMSRDRFPSEDE Q9RNG5 475 475 -
GLYRTEIPFMLQSGFPSEEE PT1P_ECOLI 459 459 -
GLYRTEIPFMLQSGFPSEEE Q8X6K3 459 459 -
GLYRTEIPFMLQSGFPSEEE Q8Z411 459 459 -
GLFRSEFLFMNRRGALPDEE Q8Y2I8 302 302 -
GLYRTEFLFLQRNKLPDEEE Q9PDH7 308 308 -
GLFRSEFLYLNRDTMPSEDE Q9JWF8 298 298 -
GLFRSEFLYLNRDTMPSEDE Q9JXH7 298 298 -
GLFRTEFLYMRSLQPPTEDE PT1_BORBU 294 294 -
GLLRTEFLFHESATLPDEEE Q8VP40 290 290 -
GLFRSEFLFMNRRDELPGED PT1_ALCEU 305 305 -
GLFRTEFQFMVAEELPRLEA Q9A9W2 472 472 -
GLMRTEFLFLERGSTPTEDE PTF1_XANCP 563 563 -
GLYRTEISFLLQHRFPSEEE Q9KU52 459 459 -
GLLRTEFLFLDRETPPDEDE Q9AAQ9 598 598 -
GLLRTEFLFLDRETPPDEDE Q9AAZ4 572 572 -
GLFRTELLFMRHMHLPSEDM Q98FU8 299 299 -
GLFRTEMLYMDRDSAPDEQE YPDD_ECOLI 402 402 -
GLMRTEFLFLERDHAPDEDA Q8XVH0 562 562 -
GLFRTEMLYMDRDSEPDEQE Q8XBQ8 402 402 -
GLLRTEFLFVNREAPPGEDE PTF1_RHOCA 561 561 -
GLLRSEFLFEDRTAPPDEDE Q8XQE5 581 581 -
GLFRTEILYMDRAAAPSEEE Q8ZIT3 424 424 -
GLLRTEFVFMNNARAPDLAT Q9HY55 685 685 -
GLLRTEFLFLERRAAPDEEE Q9HXN5 568 568 -
GLFRTELCFLSATEEPSVDE Q93MZ3 292 292 -
GLFRTEFLFLDDSANAPSEE Q9KZP1 285 285 -
GLFRTELQFMVASTFPRSEQ Q8YJ96 471 471 -
GLFRTELQFMIASTMPKAEE Q92MK4 471 471 -
GLFRTQFEFLVYSTLPRRER Q9EZA6 476 476 -
GLFRTELQFMVASTFPRAEA Q98G92 471 471 -
GLFRTELQFMVGQSLPRTSD Q9EYJ0 471 471 -

Motif 2 width=16
Element Seqn Id St Int Rpt
DFFSIGTNDLIQYTMA PT1_BACHD 448 134 -
DFFSIGTNDLIQYTLA PT1_BACME 448 134 -
DFFSIGTNDLIQYTMA PT1_BACSU 447 134 -
DFFSIGTNDLIQYTMA PT1_BACSP 453 134 -
DFFSIGTNDLIQYTMA PT1_BACST 453 134 -
DFFSIGTNDLIQYTMA PT1_STRMU 451 136 -
DFFSIGTNDLIQYTMA Q9WXK9 451 136 -
DFFSIGTNDLIQYTMA Q97QM7 451 136 -
DFFSIGTNDLIQYTMA Q99Z66 451 136 -
DFFSIGTNDLIQYTLA PT1_STAAU 449 134 -
DFFSIGTNDLIQYTLA Q99V14 449 134 -
DFFSIGTNDLIQYTLA Q931U2 449 134 -
DFFSIGTNDLIQYTMA Q8VP88 451 136 -
DFFSIGTNDLIQYTLA Q97EM3 446 134 -
DFFSIGTNDLIQYTMA PT1_STRSL 451 136 -
DFFSIGTNDLIQYTMA PT1_LACLA 451 136 -
DFFSIGTNDLIQYTMA Q9AHU0 451 136 -
DFFSIGTNDLIQYTMA PT1_LACLC 451 136 -
DFFSIGTNDLIQYTMA Q9EYQ8 448 134 -
DFFSIGTNDLIQYTLA Q8XHW9 445 134 -
DFFSIGTNDLIQYSFA PT1_MYCCA 447 133 -
DFFSIGTNDLTQYTLA PT1_HAEIN 447 134 -
DFFSIGTNDLTQYTLA PT1_ECOLI 447 134 -
DFFSIGTNDLTQYTLA Q8XBL3 447 134 -
DFFSIGTNDLTQYTLA PT1_SALTY 447 134 -
DFFSIGTNDLTQYTLA Q8ZCJ2 447 134 -
DFFSIGTNDLTQYTLA Q9CMD3 447 134 -
DFFSIGTNDLIQYTMA PT1_STACA 449 134 -
DFFSIGTNDLIQYTMA PT1_LACSK 448 134 -
SFFSIGTNDLTQYTLA Q9KTD7 447 134 -
DFFSIGTNDLIQYSMA Q9KJV2 449 134 -
DFFSIGTNDLIQYSFA Q9RGC5 451 136 -
DFFSIGTNDLTQYTLA PT1_BUCAI 447 134 -
DFFSIGTNDLIQYSFA PT1_MYCPN 443 129 -
DFLSIGTNDLIQYSMA Q98PW7 447 138 -
DFMSIGTNDLIGYAMA Q93TM5 445 133 -
DFFSIGSNDLIQYSFA PT1_MYCGE 443 129 -
DFISVGTNDLTQYLLA Q8ZHU9 613 134 -
DFLSVGSNDLTQYLLA Q9X4P3 620 133 -
DFLSVGSNDLTQYLLA O87685 620 133 -
DFISVGSNDLTQYLLA Q9RNG5 628 133 -
DFISVGTNDLTQYILA PT1P_ECOLI 613 134 -
DFISVGTNDLTQYILA Q8X6K3 613 134 -
DFISVGTNDLTQYILA Q8Z411 613 134 -
DFLSIGTNDLIQYTLA Q8Y2I8 462 140 -
DFLSIGTNDLVQYLLA Q9PDH7 463 135 -
DFISVGTNDLIQYILS Q9JWF8 455 137 -
DFISVGTNDLIQYILS Q9JXH7 455 137 -
KFFSIGTNDLTQYVLA PT1_BORBU 449 135 -
DFFSIGTNDLTQYIMA Q8VP40 442 132 -
DFLSIGTNDLIQYTLA PT1_ALCEU 462 137 -
DFVSVGTNDLMQYMFA Q9A9W2 626 134 -
DFFSIGTNDLTQYVLA PTF1_XANCP 712 129 -
DFVSVGTNDLTQYLLA Q9KU52 612 133 -
DFLSIGTNDLTQYVLA Q9AAQ9 747 129 -
DFLSIGTNDLTQYVLA Q9AAZ4 721 129 -
AFFSIGTNDLTQYIMA Q98FU8 452 133 -
DFFSIGSNDMTQYLYA YPDD_ECOLI 556 134 -
DFFSIGTNDLTQYTLA Q8XVH0 711 129 -
DFFSIGSNDMTQYLYA Q8XBQ8 556 134 -
DFFSIGTNDLTQYALA PTF1_RHOCA 709 128 -
DFFSIGTNDLTQYTLA Q8XQE5 729 128 -
DFLSIGSNDLTQYLLA Q8ZIT3 578 134 -
DFFSVGTNDLTQYTLA Q9HY55 833 128 -
DFLSIGTNDLSQYALA Q9HXN5 717 129 -
DFVSIGTNDLTQYTMA Q93MZ3 439 127 -
EFLSLGTNDLAQYTFA Q9KZP1 431 126 -
DFVSVGSNDLFQFLMA Q8YJ96 626 135 -
DFVSVGSNDLFQFAMA Q92MK4 625 134 -
DFLSIGTNDLIQFFFA Q9EZA6 633 137 -
DFVSVGSNDLFQFVMA Q98G92 626 135 -
DFISVGSNDLFQFLFA Q9EYJ0 625 134 -

Motif 3 width=16
Element Seqn Id St Int Rpt
DRMNERVSYLYQPYHP PT1_BACHD 465 1 -
DRMNERVSYLYQPYNP PT1_BACME 465 1 -
DRMNERVSYLYQPYNP PT1_BACSU 464 1 -
DRMNERVAYLYQPYNP PT1_BACSP 470 1 -
DRMNERVAYLYQPYNP PT1_BACST 470 1 -
DRMNEQVSYLYQPYNP PT1_STRMU 468 1 -
DRMNEQVSYLYQPYNP Q9WXK9 468 1 -
DRMNEQVSYLYQPYNP Q97QM7 468 1 -
DRMNEQVSYLYQPYNP Q99Z66 468 1 -
DRMSERVSYLYQPYNP PT1_STAAU 466 1 -
DRMSERVSYLYQPYNP Q99V14 466 1 -
DRMSERVSYLYQPYNP Q931U2 466 1 -
DRMNEQVSYLYQPYNP Q8VP88 468 1 -
DRMNEKVSYLYNPMHP Q97EM3 463 1 -
DRMNEQVSYLYQPYNP PT1_STRSL 468 1 -
DRMNEQVSYLYQPYNP PT1_LACLA 468 1 -
DRMNEQVSYLYQPYNP Q9AHU0 468 1 -
DRMNEQVSYLYQPYNP PT1_LACLC 468 1 -
DRMSERVSYLYQPYNP Q9EYQ8 465 1 -
DRMSEKVSYLYNPMHP Q8XHW9 462 1 -
DRMNQNVSYLYQPLNP PT1_MYCCA 464 1 -
DRGNEFISHLYNPMHP PT1_HAEIN 464 1 -
DRGNDMISHLYQPMSP PT1_ECOLI 464 1 -
DRGNDMISHLYQPMSP Q8XBL3 464 1 -
DRGNDMISHLYQPMSP PT1_SALTY 464 1 -
DRGNELISHLYNPMSP Q8ZCJ2 464 1 -
DRGNELISHLYNPMSP Q9CMD3 464 1 -
DRMSERVSYLYQPYIS PT1_STACA 466 1 -
DRMNERVSYLYQPYNP PT1_LACSK 465 1 -
DRGNEMISHLYNPLSP Q9KTD7 464 1 -
DRGNEHVSYLYQPYNP Q9KJV2 466 1 -
DRMNEKVAYLYQTLNP Q9RGC5 468 1 -
DRGNDLISHLYNPMNP PT1_BUCAI 464 1 -
DRMNKNVSYLYQPLNP PT1_MYCPN 460 1 -
DRMNEKISYLYQPLNP Q98PW7 464 1 -
DRTNQDVAYLYQPYHP Q93TM5 462 1 -
DRMNKNVSYLYQPLNP PT1_MYCGE 460 1 -
DRNNTRVASLYDSLHP Q8ZHU9 630 1 -
DRNNPRVADLYDYLHP Q9X4P3 637 1 -
DRNNPRVADLYDYLHP O87685 637 1 -
DRNNARVAALYDPLHP Q9RNG5 645 1 -
DRNNTRVANIYDSLHP PT1P_ECOLI 630 1 -
DRNNTRVANIYDSLHP Q8X6K3 630 1 -
DRNNTRVASIYDSLHP Q8Z411 630 1 -
DRADNAVAHLYDPLHP Q8Y2I8 479 1 -
DRNNAAISEIYSPLHP Q9PDH7 480 1 -
DRGDDSVSHLYQPGHP Q9JWF8 472 1 -
DRGDDSVSHLYQPGHP Q9JXH7 472 1 -
DRGNQKISNLYDKYNP PT1_BORBU 466 1 -
DRGNSTVAKLVDYRND Q8VP40 459 1 -
DRADNAVAHLFDPLHP PT1_ALCEU 479 1 -
DRGNPRVSDRYDPLSP Q9A9W2 643 1 -
DRQNPELAAEASSLHP PTF1_XANCP 729 1 -
DRNNARVADVYESMHP Q9KU52 629 1 -
DRGNPELAAGIDALHP Q9AAQ9 764 1 -
DRGNPELAAGIDALHP Q9AAZ4 738 1 -
DRLNPTVAKLNDVTNP Q98FU8 469 1 -
DRNNPRVSPLYNPITP YPDD_ECOLI 573 1 -
DRQHPDLAAEADSLHP Q8XVH0 728 1 -
DRNNPRVSPLYNPITP Q8XBQ8 573 1 -
DRMHPVLAKQADGLHP PTF1_RHOCA 726 1 -
DRGHAGLAARVDALHP Q8XQE5 746 1 -
DRDNAKVSEHYHCLPP Q8ZIT3 595 1 -
DRGHPSLSAQADGLHP Q9HY55 850 1 -
DRCHAGLADRIDALHP Q9HXN5 734 1 -
DRMSPELAYLTDPWQP Q93MZ3 456 1 -
DRQVGAVSRLQDPWQP Q9KZP1 448 1 -
DRGNSLISDRFDQLSP Q8YJ96 643 1 -
DRGNARVSERFDILGR Q92MK4 642 1 -
DRAYPKLAERYDWLSP Q9EZA6 650 1 -
DRGNTQLANRFDTLSA Q98G92 643 1 -
DRGNAKVSERFDTMSA Q9EYJ0 642 1 -

Motif 4 width=13
Element Seqn Id St Int Rpt
GMCGEMAGDEVAI PT1_BACHD 501 20 -
GMCGEMAGDEIAI PT1_BACME 501 20 -
GMCGEMAGDEIAI PT1_BACSU 500 20 -
GMCGEMAGDPIAI PT1_BACSP 506 20 -
GMCGEMAGDPIAI PT1_BACST 506 20 -
GMCGEMAGDQTAV PT1_STRMU 504 20 -
GMCGEMAGDQKAV Q9WXK9 504 20 -
GMCGEMAGDQQAV Q97QM7 504 20 -
GMCGEMAGDQQAV Q99Z66 504 20 -
GMCGEMAGDETAI PT1_STAAU 502 20 -
GMCGEMAGDETAI Q99V14 502 20 -
GMCGEMAGDETAI Q931U2 502 20 -
GMCGEMAGDQTAV Q8VP88 504 20 -
GMCGEMAGDEKAI Q97EM3 499 20 -
GMCGEMAGDQTAV PT1_STRSL 504 20 -
GMCGEMAGDQTAV PT1_LACLA 504 20 -
GMCGEMAGDQTAV Q9AHU0 504 20 -
GMCGEMAGDQTAV PT1_LACLC 504 20 -
GMCGEMAGDETAI Q9EYQ8 501 20 -
GMCGEMAGDERAI Q8XHW9 498 20 -
GMCGEMAGDSKAL PT1_MYCCA 500 20 -
GMCGELAGDERAT PT1_HAEIN 500 20 -
GMCGELAGDERAT PT1_ECOLI 500 20 -
GMCGELAGDERAT Q8XBL3 500 20 -
GMCGELAGDERAT PT1_SALTY 500 20 -
GMCGELAGDERAT Q8ZCJ2 500 20 -
GMCGELAGDEKAA Q9CMD3 500 20 -
GMCGEMAGDQTAI PT1_STACA 502 20 -
GMCGEAAGDSIMA PT1_LACSK 501 20 -
GMCGELAGDERAT Q9KTD7 500 20 -
GMCGEAAGDPIMV Q9KJV2 502 20 -
GMCGEMAGDINAV Q9RGC5 504 20 -
GMCGELAGDERAT PT1_BUCAI 500 20 -
GMCGEMAGEPLAI PT1_MYCPN 496 20 -
GMCGEMAGNPEAI Q98PW7 500 20 -
AMCGEMAGDPIAV Q93TM5 498 20 -
GMCGEMASDQYAI PT1_MYCGE 496 20 -
SLCGEMAGDPMGA Q8ZHU9 666 20 -
SICGEMAGDPAAA Q9X4P3 673 20 -
SICGEMAGDPSAA O87685 673 20 -
SICGEMASDPLAV Q9RNG5 681 20 -
RLCGEMAGDPMCV PT1P_ECOLI 666 20 -
RLCGEMAGDPMCV Q8X6K3 666 20 -
RLCGEMAGDPMCV Q8Z411 666 20 -
SVCGEMAGDATMT Q8Y2I8 515 20 -
AICGEIAGDPHYV Q9PDH7 516 20 -
SVCGEMAGDTAFT Q9JWF8 508 20 -
SVCGEMAGDTAFT Q9JXH7 508 20 -
SVCGELGGDDAGA PT1_BORBU 502 20 -
SMCGEMAGDTQQT Q8VP40 495 20 -
AVCGEMAGDPSMT PT1_ALCEU 515 20 -
SVCGEMAGRPLEA Q9A9W2 679 20 -
GVCGGLAGDPFGA PTF1_XANCP 765 20 -
CVCGELAGDPIGA Q9KU52 665 20 -
GVCGGLASDLDAT Q9AAQ9 800 20 -
GVCGGLASDLDAT Q9AAZ4 774 20 -
GMCGEAAGRPDLI Q98FU8 505 20 -
GICGELGGESRYL YPDD_ECOLI 609 20 -
GVCGGLAGDPFGA Q8XVH0 764 20 -
GICGELGGESRYL Q8XBQ8 609 20 -
GACGGIAGDPVGA PTF1_RHOCA 762 20 -
GVCGALASDLAAV Q8XQE5 782 20 -
GLCGELAAKDSVL Q8ZIT3 631 20 -
GVCGELAADPLAL Q9HY55 886 20 -
GVCGALASDPLAT Q9HXN5 770 20 -
GVCGEAAADPLLA Q93MZ3 492 20 -
GVCGEAAADPLLA Q9KZP1 484 20 -
TLCGEMAGRPLTA Q8YJ96 679 20 -
TLCGEMASKPLSA Q92MK4 678 20 -
GICGEMGGRTLTA Q9EZA6 686 20 -
TLCGELAGKPISA Q98G92 679 20 -
SLCGEMASKPIGA Q9EYJ0 678 20 -