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PR01609

Identifier
CD36FAMILY  [View Relations]  [View Alignment]  
Accession
PR01609
No. of Motifs
6
Creation Date
23-DEC-2001
Title
Adhesion molecule CD36 family signature
Database References
PRINTS; PR01610 CD36ANTIGEN; PR01611 LIMPII
PFAM; PF01130 CD36
INTERPRO; IPR002159
MIM; 173510; 602257
Literature References
1. OKUMURA, T. AND JAMIESON, G.A.
Platelet glycocalicin. Orientation of glycoproteins on the human platelet
surface.
J.BIOL.CHEM. 251 5944-5949 (1976).
 
2. NICHOLSON, A.C., FEBBRAIO, M.,  HAN, J., SILVERSTEIN, R.L. AND
HAJJAR, D.P.
CD36 in atherosclerosis. The role of a class B macrophage scavenger receptor.
ANN.N.Y.ACAD.SCI. 902 128-131 (2000).
 
3. SILVERSTEIN, R.L. AND FEBBRAIO, M.
CD36 and atherosclerosis.
CURR.OPIN.LIPIDOL. 11 483-491 (2000). 
 
4. SAVILL, J., HOGG, N., REN, Y. AND HASLETT, C.
Thrombospondin cooperates with CD36 and the vitronectin receptor
in macrophage recognition of neutrophils undergoing apoptosis. 
J.CLIN.INVEST. 90 1513-1522 (1989).
 
5. TANDON, NN., KRALISZ, U. AND JAMIESON, GA.
Identification of glycoprotein IV (CD36) as a primary receptor 
for platelet-collagen adhesion.
J.BIOL.CHEM. 264 7576-7583 (1989).
 
6. MCGREGOR, J.L., CATIMEL, B., PARMENTIER, S., CLEZARDIN, P., DECHAVANNE, M. 
AND LEUNG, L.L.
Rapid purification and partial characterization of human platelet
glycoprotein IIIb. Interaction with thrombospondin and its role in platelet 
aggregation.
J.BIOL.CHEM. 264 501-506 (1989).
 
7. BARNWELL, J.W., ASCH, A.S., NACHMAN, R.L., YAMAYA, M., AIKAWA, M. AND
INGRAVALLO, P.
A human 88-kD membrane glycoprotein (CD36) functions in vitro as a receptor
for a cytoadherence ligand on Plasmodium falciparum-infected erythrocytes.
J.CLIN.INVEST. 84 765-772 (1989).
 
8. BULL, H.A., BRICKELL, P.M. AND DOWD, P.M.
Src-related protein tyrosine kinases are physically associated with the 
surface antigen CD36 in human dermal microvascular endothelial cells.
FEBS LETT. 351 41-44 (1994).
 
9. MIYAOKA, K., KUWASAKO, T., HIRANO, K., NOZAKI, S., YAMASHITA, S. 
AND MATSUZAWA, Y.
CD36 deficiency associated with insulin resistance.
LANCET 357 686-687 (2001).
 
10. VEGA, M.A., SEGUI-REAL, B., GARCIA, J.A., CALES, C., RODRIGUEZ, F.,
VANDERKERCKHOVE, J. AND SANDOVAL, I.V.
Cloning, sequencing, and expression of a cDNA encoding rat LIMP II, a novel
74-kDa lysosomal membrane protein related to the surface adhesion protein
CD36.
J.BIOL.CHEM. 266 16818-16824 (1991). 
 
11. FUJITA, H., EZAKI, J., NOGUCHI, Y., KONO, A., HIMENO, M. AND KATO, K.
Isolation and sequencing of a cDNA clone encoding 85kDa sialoglycoprotein
in rat liver lysosomal membranes.
BIOCHEM.BIOPHYS.RES.COMMUN. 178 444-452 (1991). 
 
12. FUJITA, H., TAKATA, Y., KONO, A., TANAKA, Y., TAKAHASHI, T., HIMENO, M.
AND KATO, K.
Isolation and sequencing of a cDNA clone encoding the 85 kDa human lysosomal
sialoglycoprotein (hLGP85) in human metastatic pancreas islet tumor cells.
BIOCHEM.BIOPHYS.RES.COMMUN. 184 604-611 (1992). 

Documentation
CD36 is a transmembrane, highly glycosylated, 88kDa glycoprotein [1] 
expressed by monocytes, macrophages, platelets, microvascular endothelial 
cells and adipose tissue [2]. It is a multifunctional receptor that binds
to oxidised LDL (OxLDL), long chain fatty acids, anionic phospholipids,
apoptotic cells, thrombospondin (TSP), collagen and Plasmodium falciparum-
infected erythrocytes [2].
 
CD36 has numerous cellular functions. It is a type B scavenger receptor, 
playing a major role in the uptake of OxLDL by macrophages [3]. The lipid-
rich macrophages are then differentiated into foam cells and contribute to
the formation of atherosclerotic lesions [3]. In addition, CD36 of macro-
phages, together with TSP and the integrin alphav beta3, can phagocytose 
apoptotic neutrophils [4]. Furthermore, the protein is one of the receptors
of collagen in platelet adhesion and aggregation [5,6]. CD36 can also
mediate cytoadherence of Plasmodium falciparum-infected erythrocytes to the
endothelium of post-capillary venules of different organs [7]. Moreover, 
cytoplasmic CD36 plays an important role in signal transduction by inter-
acting with Src family tyrosine kinases [8]. Deficiency in CD36 in Asian
and African populations has been associated with insulin resistance [9]. 
 
Lysosome membrane protein II (LIMP II) is a 478-residue glycoprotein
expressed in the membrane of lysosomes and secretory granules with lysosomal
properties [10]. The N-terminal segment (residues ~4-26) constitute an 
uncleavable signal peptide [10]. LIMP II possesses an additional C-terminal
hydrophobic region that, together with the signal peptide, may anchor the
protein to the membrane [10]. The major portion of the protein resides on
the luminal side and contains 11 potential N-glycosylation sites and 5 
cysteine residues. The N- and C-terminal ends of the protein constitute
short cytoplasmic tails. 
 
Comparison of the sequence to that of other lysosomal membrane glycoproteins
reveals no similarity. Glycine-tyrosine residues (the so-called GY motif),
believed to constitute an important signal for delivery of lysosomal 
membrane glycoproteins to lysosomes, are not contained in the cytoplasmic 
tail [11,12]. The protein thus appears to be a unique LIMP that does not 
require tyrosine residues for targeting to lysosomes [11]. Sequence database 
searches reveal extensive similarity between LIMP II and the cell surface 
protein CD36 involved in cell adhesion [10]. 
 
CD36FAMILY is a 6-element fingerprint that provides a signature for the
adhesion molecule CD36 family. The fingerprint was derived from an initial
alignment of 6 sequences: the motifs were drawn from conserved regions
spanning the lumenal domain. Seven iterations on SPTR40_18f were required
to reach convergence, at which point a true set comprising 29 sequences
was identified. Several partial matches were also found, all of which are
proteins related to the CD36 family that fail to make significant matches
with one or more motifs.
Summary Information
  29 codes involving  6 elements
2 codes involving 5 elements
3 codes involving 4 elements
1 codes involving 3 elements
4 codes involving 2 elements
Composite Feature Index
6292929292929
5122122
4332121
3110001
2310013
123456
True Positives
CD36_BOVIN    CD36_HUMAN    CD36_MESAU    CD36_MOUSE    
CD36_RAT CRQ_DROME LYII_HUMAN LYII_RAT
O02351 O18824 O35114 O35754
O88548 P97943 Q14016 Q24336
Q60417 Q61009 Q9CWJ7 Q9GPH7
Q9GPH8 Q9U1G3 Q9U3U2 Q9VDD3
Q9VJA7 Q9VM10 Q9VPQ1 Q9W067
Q9W0X0
True Positive Partials
Codes involving 5 elements
Q9VLU7 Q9W0W9
Codes involving 4 elements
Q9VET1 Q9XTT3 Q9Y121
Codes involving 3 elements
Q9W0X1
Codes involving 2 elements
Q19140 Q19344 YRN3_CAEEL YX13_CAEEL
Sequence Titles
CD36_BOVIN  Platelet glycoprotein IV (GPIV) (GPIIIB) (CD36 antigen) (PAS IV) (PAS-4 protein) - Bos taurus (Bovine). 
CD36_HUMAN Platelet glycoprotein IV (GPIV) (GPIIIB) (CD36 antigen) (PAS IV) (PAS-4 protein) - Homo sapiens (Human).
CD36_MESAU Platelet glycoprotein IV (GPIV) (GPIIIB) (CD36 antigen) (PAS IV) (PAS-4 protein) - Mesocricetus auratus (Golden hamster).
CD36_MOUSE Platelet glycoprotein IV (GPIV) (GPIIIB) (CD36 antigen) (PAS IV) (PAS-4 protein) - Mus musculus (Mouse).
CD36_RAT Platelet glycoprotein IV (GPIV) (GPIIIB) (CD36 antigen) (PAS IV) (PAS- 4 protein) (Fatty acid transport protein) (Fatty acid translocase) (Adipocyte membrane protein) - Rattus norvegicus (Rat).
CRQ_DROME Croquemort protein (D-CD36) - Drosophila melanogaster (Fruit fly).
LYII_HUMAN Lysosome membrane protein II (LIMP II) (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) - Homo sapiens (Human).
LYII_RAT Lysosome membrane protein II (LIMP II) (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) - Rattus norvegicus (Rat).
O02351 SENSORY NEURON MEMBRANE PROTEIN-1 - Antheraea polyphemus (Polyphemus moth).
O18824 SCAVENGER RECEPTOR CLASS B TYPE I - Bos taurus (Bovine).
O35114 CD36 ANTIGEN (COLLAGEN TYPE I RECEPTOR, THROMBOSPONDIN RECEPTOR)-LIKE 2 (MLGP85/LIMP II) - Mus musculus (Mouse).
O35754 FATTY ACID TRANSPORT PROTEIN (FATTY ACID TRANSPORTER) - Rattus norvegicus (Rat).
O88548 TYPE II PNEUMOCYTE CD36-RELATED CLASS B SCAVENGER RECEPTOR - Rattus norvegicus (Rat).
P97943 SCAVENGER RECEPTOR CLASS B TYPE I - Rattus norvegicus (Rat).
Q14016 CLA-1 - Homo sapiens (Human).
Q24336 EPITHELIAL MEMBRANE PROTEIN - Drosophila melanogaster (Fruit fly).
Q60417 CD36-RELATED CLASS B SCAVENGER RECEPTOR HASR-BI - Cricetulus griseus (Chinese hamster).
Q61009 SCAVENGER RECEPTOR CLASS B TYPE I (SCAVENGER RECEPTOR CLASS B1) - Mus musculus (Mouse).
Q9CWJ7 SCAVENGER RECEPTOR CLASS B1 - Mus musculus (Mouse).
Q9GPH7 SENSORY NEURON MEMBRANE PROTEIN 1 - Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm).
Q9GPH8 SENSORY NEURON MEMBRANE PROTEIN 2 - Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm).
Q9U1G3 SENSORY NEURON MEMBRANE PROTEIN-1 - Heliothis virescens (Noctuid moth) (Owlet moth).
Q9U3U2 SENSORY NEURON MEMBRANE PROTEIN-1 - Bombyx mori (Silk moth).
Q9VDD3 CG7000 PROTEIN - Drosophila melanogaster (Fruit fly).
Q9VJA7 CG5750 PROTEIN - Drosophila melanogaster (Fruit fly).
Q9VM10 CG12789 PROTEIN - Drosophila melanogaster (Fruit fly).
Q9VPQ1 CRQ PROTEIN - Drosophila melanogaster (Fruit fly).
Q9W067 CG1887 PROTEIN - Drosophila melanogaster (Fruit fly).
Q9W0X0 EMP PROTEIN - Drosophila melanogaster (Fruit fly).

Q9VLU7 CG7227 PROTEIN - Drosophila melanogaster (Fruit fly).
Q9W0W9 CG3829 PROTEIN - Drosophila melanogaster (Fruit fly).

Q9VET1 BCDNA:GH08773 PROTEIN - Drosophila melanogaster (Fruit fly).
Q9XTT3 Y49E10.20 PROTEIN - Caenorhabditis elegans.
Q9Y121 BCDNA.GH08773 - Drosophila melanogaster (Fruit fly).

Q9W0X1 CG2736 PROTEIN - Drosophila melanogaster (Fruit fly).

Q19140 F07A5.3 PROTEIN - Caenorhabditis elegans.
Q19344 F11C1.3 PROTEIN - Caenorhabditis elegans.
YRN3_CAEEL Hypothetical 61.0 kDa protein R07B1.3 in chromosome X - Caenorhabditis elegans.
YX13_CAEEL Hypothetical 62.6 kDa protein C03F11.3 in chromosome X precursor - Caenorhabditis elegans.
Scan History
SPTR40_18f 7  50   NSINGLE    
Initial Motifs
Motif 1  width=22
Element Seqn Id St Int Rpt
KTGTTVYRQFWIFDVQNPDDVA CD36_MOUSE 55 55 -
KTGTTVYRQFWVFDVQNPEEVA CD36_RAT 55 55 -
KTGTEVYRQFWIFDVQNPQEVM CD36_HUMAN 55 55 -
KPPLPVYTQFYFFNVTNPEEIL LYII_HUMAN 54 54 -
KTGTDVYRQFWIFDVQNPDEVT CD36_BOVIN 55 55 -
KPPLPVYIQFYFFNVTNPEEIL LYII_RAT 54 54 -

Motif 2 width=13
Element Seqn Id St Int Rpt
KIKVKQRGPYTYR CD36_MOUSE 81 4 -
KIKVIQRGPYTYR CD36_RAT 81 4 -
NIQVKQRGPYTYR CD36_HUMAN 81 4 -
TPRVEEVGPYTYR LYII_HUMAN 79 3 -
KIKVKQRGPYTYR CD36_BOVIN 81 4 -
IPLLEEVGPYTYR LYII_RAT 79 3 -

Motif 3 width=20
Element Seqn Id St Int Rpt
TVSFVQPNGAIFEPSLSVGT CD36_MOUSE 110 16 -
TVSFVQPNGAIFEPSLSVGT CD36_RAT 110 16 -
TVSFLQPNGAIFEPSLSVGT CD36_HUMAN 110 16 -
TISAVSNKAYVFERDQSVGD LYII_HUMAN 107 15 -
TVSFLQPNGAIFEPLLSVGT CD36_BOVIN 110 16 -
TISAVTNKAYIFERNQSVGD LYII_RAT 107 15 -

Motif 4 width=25
Element Seqn Id St Int Rpt
CDMINGTDAASFPPFVEKSRTLRFF CD36_MOUSE 242 112 -
CDMINGTDAASFPPLGEKSRTLRFF CD36_RAT 242 112 -
CDMINGTDAASFPPFVEKSQVLQFF CD36_HUMAN 242 112 -
CNMINGTDGDSFHPLITKDEVLYVF LYII_HUMAN 244 117 -
CDLINGTDAASFPPLVEKTRVLQFF CD36_BOVIN 242 112 -
CNMINGTDGDSFHPLISKDETLYIF LYII_RAT 244 117 -

Motif 5 width=25
Element Seqn Id St Int Rpt
CTSYGVLDIGKCKEGKPVYISLPHF CD36_MOUSE 321 54 -
CTSYGVLDIGKCKEGKPVYNSLPHF CD36_RAT 321 54 -
CTSYGVLDISKCKEGRPVYISLPHF CD36_HUMAN 321 54 -
CLGSGVLNVSICKNGAPIIMSFPHF LYII_HUMAN 317 48 -
CTLYGVLDIGKCKEGKPVYISLPHF CD36_BOVIN 321 54 -
CMDAGVLNVSICKNGAPIIMSFPHF LYII_RAT 317 48 -

Motif 6 width=22
Element Seqn Id St Int Rpt
TYLDVEPITGFTLQFAKRLQVN CD36_MOUSE 368 22 -
TYLDVEPITGFTLQFSKRLQVN CD36_RAT 368 22 -
TYLDIEPITGFTLQFAKRLQVN CD36_HUMAN 368 22 -
TFVDINPLTGIILKAAKRFQIN LYII_HUMAN 364 22 -
TYLDVEPITGFTLRFAKRLQVN CD36_BOVIN 368 22 -
SFVDINPLTGIILRGAKRFQIN LYII_RAT 364 22 -
Final Motifs
Motif 1  width=22
Element Seqn Id St Int Rpt
EIPVPFYLSVYFFEVVNPNEVL Q61009 58 58 -
EIPVPFYLSVYFFEVVNPNEVL Q9CWJ7 58 58 -
EIPVPFYLSVYFFEVVNPSEIL Q60417 58 58 -
EIPVPFYLSVYFFEVVNPSEVL O88548 58 58 -
EIPVPFYLSVYFFEVVNPSEVL P97943 58 58 -
EIPIPFYLSVYFFDVMNPSEIL Q14016 58 58 -
KTGTTVYRQFWIFDVQNPDEVA CD36_MESAU 55 55 -
KTGTTVYRQFWIFDVQNPEEVA O35754 56 56 -
KTGTTVYRQFWIFDVQNPDDVA CD36_MOUSE 55 55 -
EIPVPFYLSVYFFNIVNPEGII O18824 58 58 -
KTGTTVYRQFWVFDVQNPEEVA CD36_RAT 55 55 -
KTGTEVYRQFWIFDVQNPQEVM CD36_HUMAN 55 55 -
KPPLPVYTQFYFFNVTNPEEIL LYII_HUMAN 54 54 -
KTGTDVYRQFWIFDVQNPDEVT CD36_BOVIN 55 55 -
KPPLPVYIQFYFFNVTNPEEIL LYII_RAT 54 54 -
KPPLPVYIQFYFFNVTNPEEIL O35114 55 55 -
EAPIPIYLSFYMFNWTNPEDIR CRQ_DROME 59 59 -
EAPIPIYLSFYMFNWTNPEDIR Q9VPQ1 59 59 -
KPPVEPRISLYIYNVTNADDFL Q24336 67 67 -
KPPVEPRISLYIYNVTNADDFL Q9W0X0 67 67 -
KIPFALDFKIYLFNYTNPEEVQ Q9GPH7 54 54 -
KIPFALDFKVYIFNFTNAEEVQ Q9U1G3 54 54 -
KVPFALDFKVYIFNYTNVDEIQ O02351 54 54 -
KPGVIRLTKLYIYNVTNPDGFL Q9W067 37 37 -
KIPFALDFKIYLFNYTNAEDVQ Q9U3U2 54 54 -
KLPIPLIFKVYFFNVTNAEGIN Q9GPH8 54 54 -
NTPFPLHFYIYVFNVTNPDEVS Q9VDD3 53 53 -
SPPIDLSLDIYLYNWTNPEDFG Q9VM10 29 29 -
ELPIPVYVYMYLWNWTNAADVQ Q9VJA7 59 59 -

Motif 2 width=13
Element Seqn Id St Int Rpt
KPVVRERGPYVYR Q61009 83 3 -
KPVVRERGPYVYR Q9CWJ7 83 3 -
KPVVRERGPYVYR Q60417 83 3 -
KPVVRERGPYVYR O88548 83 3 -
KPVVRERGPYVYR P97943 83 3 -
KPQVRERGPYVYR Q14016 83 3 -
KIKVKQRGPYTYR CD36_MESAU 81 4 -
KIKVKQRGPYTYR O35754 82 4 -
KIKVKQRGPYTYR CD36_MOUSE 81 4 -
KPQVQEHGPYVYR O18824 83 3 -
KIKVIQRGPYTYR CD36_RAT 81 4 -
NIQVKQRGPYTYR CD36_HUMAN 81 4 -
TPRVEEVGPYTYR LYII_HUMAN 79 3 -
KIKVKQRGPYTYR CD36_BOVIN 81 4 -
IPLLEEVGPYTYR LYII_RAT 79 3 -
IPLLEEVGPYTYR O35114 80 3 -
KPNFVEMGPYTFL CRQ_DROME 85 4 -
KPNFVEMGPYTFL Q9VPQ1 85 4 -
KAIVDEVGPYVYS Q24336 93 4 -
KAIVDEVGPYVYS Q9W0X0 93 4 -
APIVKEVGPYYFE Q9GPH7 79 3 -
TPILKEIGPYHFD Q9U1G3 79 3 -
KPIVKEIGPYYFE O02351 79 3 -
KPHLQEVGPFVYR Q9W067 62 3 -
VPIVKEVGPFYFE Q9U3U2 79 3 -
RPILQEIGPYVYK Q9GPH8 79 3 -
KPRLQEVGPFVFD Q9VDD3 78 3 -
KPILEQVGPYRFI Q9VM10 55 4 -
KPIFAQLGPYVYR Q9VJA7 85 4 -

Motif 3 width=20
Element Seqn Id St Int Rpt
TVSFVENRSLHFQPDKSHGS Q61009 110 14 -
TVSFVENRSLHFQPDKSHGS Q9CWJ7 110 14 -
TVSFVEHRSLHFQPDRSHGS Q60417 110 14 -
TVSYIENRSLHFQPDRSQGS O88548 110 14 -
TVSYIENRSLRFQPDRSQGS P97943 110 14 -
TVSFLEYRTFQFQPSKSHGS Q14016 110 14 -
TVSFVQPNGAIFEPSLSVGT CD36_MESAU 110 16 -
TVSFVQPNGAIFEPSLSVGT O35754 111 16 -
TVSFVQPNGAIFEPSLSVGT CD36_MOUSE 110 16 -
TVSFLEYRSYQFQPDKSRGQ O18824 110 14 -
TVSFVQPNGAIFEPSLSVGT CD36_RAT 110 16 -
TVSFLQPNGAIFEPSLSVGT CD36_HUMAN 110 16 -
TISAVSNKAYVFERDQSVGD LYII_HUMAN 107 15 -
TVSFLQPNGAIFEPLLSVGT CD36_BOVIN 110 16 -
TISAVTNKAYIFERNQSVGD LYII_RAT 107 15 -
TISAVTNKAYVFERNQSVGD O35114 108 15 -
TVAYYERRTWFFDPERSNGT CRQ_DROME 112 14 -
TVAYYERRTWFFDPERSNGT Q9VPQ1 112 14 -
TLSYNLRKIYSFREDLSVGP Q24336 120 14 -
TLSYNLRKIYSFREDLSVGP Q9W0X0 120 14 -
TITYRKMDTFYFRPELSGPG Q9GPH7 107 15 -
TITYKKRDVFYFNPEMSGPG Q9U1G3 107 15 -
TITYKRLDVFHFRPDLSGPG O02351 107 15 -
TVSYQHKKILQFVPELSIDK Q9W067 90 15 -
TINYKKIDVFLFKPELSGPG Q9U3U2 107 15 -
TIKYMLKKNFVFDPEASNGL Q9GPH8 106 14 -
TVSFTMRNTFIFNPKESLPL Q9VDD3 106 15 -
SVTYRRRSLFYFDAAGSNGS Q9VM10 83 15 -
TVTFNPRRTWFWEEELSGGK Q9VJA7 112 14 -

Motif 4 width=25
Element Seqn Id St Int Rpt
CNMINGTSGQMWAPFMTPESSLEFF Q61009 251 121 -
CNMINGTSGQMWAPFMTPESSLEFF Q9CWJ7 251 121 -
CNMINGTSGQMWAPFMTPQSSLEFF Q60417 251 121 -
CNMINGTAGQMWAPFMTPESSLEFF O88548 251 121 -
CNMINGTAGQMWAPFMTPESSLEFF P97943 251 121 -
CNMINGTSGQMWPPFMTPESSLEFY Q14016 251 121 -
CDMINGTDAASFPPFVEKSRVLRFF CD36_MESAU 242 112 -
CDMINGTDAASFPPFVEKSQTLRFF O35754 243 112 -
CDMINGTDAASFPPFVEKSRTLRFF CD36_MOUSE 242 112 -
CNMINGTSGQMWAPFMTPESSLEFY O18824 251 121 -
CDMINGTDAASFPPLGEKSRTLRFF CD36_RAT 242 112 -
CDMINGTDAASFPPFVEKSQVLQFF CD36_HUMAN 242 112 -
CNMINGTDGDSFHPLITKDEVLYVF LYII_HUMAN 244 117 -
CDLINGTDAASFPPLVEKTRVLQFF CD36_BOVIN 242 112 -
CNMINGTDGDSFHPLISKDETLYIF LYII_RAT 244 117 -
CNMINGTDGDSFHPLISKDEVLYLF O35114 245 117 -
CGIVNGTTGDMFPPKMNVNDEITIF CRQ_DROME 256 124 -
CGIVNGTTGDMFPPKMNVNDEITIF Q9VPQ1 256 124 -
CNTLAGTDGSIFPPHIDHDRILHVY Q24336 262 122 -
CNTLAGTDGSIFPPHIDHDRILHVY Q9W0X0 262 122 -
CNEYQGTDGTIFPPFLTQKDRLQSY Q9GPH7 268 141 -
CNEYQGTDGTVFPPFVPETERIQSF Q9U1G3 268 141 -
CNEFQGTDGTVFPPFLTYKDRLQSF O02351 268 141 -
CTSIAGSEGSFFPPRELTKSEVVHI Q9W067 215 105 -
CNEYQGTDGTVFPPFLTHKDRLQSF Q9U3U2 268 141 -
CNRINGSDASIFPPIDENNVPERLY Q9GPH8 268 142 -
CNTFVGTDSTVFAPGLKKEDGLFIV Q9VDD3 265 139 -
CGMTNGSAGEFQPQHLKPGDSVGLF Q9VM10 229 126 -
CGRLNGSTTDLFVPDEPKEKALTIF Q9VJA7 257 125 -

Motif 5 width=25
Element Seqn Id St Int Rpt
CRESGIQNVSTCRFGAPLFLSHPHF Q61009 323 47 -
CRESGIQNVSTCRFGAPLFLSHPHF Q9CWJ7 323 47 -
CLESGIQNVSTCRFGAPLFLSHPHF Q60417 323 47 -
CRESGIQNVSTCRFGAPLFLSQPHF O88548 323 47 -
CRESGIQNVSTCRFGAPLFLSQPHF P97943 323 47 -
CLESGIQNVSTCRFSAPLFLSHPHF Q14016 323 47 -
CTSYGVLDISKCKQGRPVYISLPHF CD36_MESAU 321 54 -
CTSYGVLDIGKCKEGKPVYISLPHF O35754 322 54 -
CTSYGVLDIGKCKEGKPVYISLPHF CD36_MOUSE 321 54 -
CRESGIQNVSTCRFNAPLFLSHPHF O18824 323 47 -
CTSYGVLDIGKCKEGKPVYNSLPHF CD36_RAT 321 54 -
CTSYGVLDISKCKEGRPVYISLPHF CD36_HUMAN 321 54 -
CLGSGVLNVSICKNGAPIIMSFPHF LYII_HUMAN 317 48 -
CTLYGVLDIGKCKEGKPVYISLPHF CD36_BOVIN 321 54 -
CMDAGVLNVSICKNGAPIIMSFPHF LYII_RAT 317 48 -
CMDSGVLNISICKNGAPIIMSFPHF O35114 318 48 -
CPKTGVVECKACRDKAPIYSSFPHF CRQ_DROME 334 53 -
CPKTGVVECKACRDKAPIYSSFPHF Q9VPQ1 334 53 -
CSPNGLFNVSLCQYDSPIMLSFPHF Q24336 339 52 -
CSPNGLFNVSLCQYDSPIMLSFPHF Q9W0X0 340 53 -
KCPPKGLMDLTKCVKAPMYASMPHF Q9GPH7 340 47 -
SCPPKGLMDLAPCMKAPMYASMPHF Q9U1G3 340 47 -
ECLPKGIMDIRKCLKVPMYVSLPHF O02351 340 47 -
EPIQGLQNISPCQYGAPVYISNPHF Q9W067 291 51 -
KCPPKGLMDLYKCIKAPMFVSMPHY Q9U3U2 340 47 -
GCLLMGVFNLMPCQGAPAIASLPHF Q9GPH8 350 57 -
RVPPKGTMNLAACVGGPLMASMPHF Q9VDD3 299 9 -
CVPSGVMNISSCRFGSPVFMSYPHF Q9VM10 308 54 -
CPRNGVLDYGPPAFNGPFYMSHPHF Q9VJA7 783 501 -

Motif 6 width=22
Element Seqn Id St Int Rpt
LFLDIHPVTGIPMNCSVKMQLS Q61009 370 22 -
LFLDIHPVTGIPMNCSVKMQLS Q9CWJ7 370 22 -
LFLDIHPVTGIPMNCSVKLQIS Q60417 370 22 -
LFLDIHPVTGIPMNCSVKMQLS O88548 370 22 -
LFLDIHPVTGIPMNCSVKMQLS P97943 370 22 -
LFLDIHPVTGIPMNCSVKLQLS Q14016 370 22 -
TYLDVEPITGFTLQFAKRLQVN CD36_MESAU 368 22 -
TYLDVEPITGFTLQFAKRLQVN O35754 369 22 -
TYLDVEPITGFTLQFAKRLQVN CD36_MOUSE 368 22 -
LFLDIHPVTGIPMNCSVKLQLS O18824 370 22 -
TYLDVEPITGFTLQFSKRLQVN CD36_RAT 368 22 -
TYLDIEPITGFTLQFAKRLQVN CD36_HUMAN 368 22 -
TFVDINPLTGIILKAAKRFQIN LYII_HUMAN 364 22 -
TYLDVEPITGFTLRFAKRLQVN CD36_BOVIN 368 22 -
SFVDINPLTGIILRGAKRFQIN LYII_RAT 364 22 -
SFVDINPLTGIILRGAKRFQIN O35114 365 22 -
FFLAVEPITGVPVQVHGRIQIN CRQ_DROME 381 22 -
FFLAVEPITGVPVQVHGRIQIN Q9VPQ1 381 22 -
FFFDVQPKMGTTLRVRARIQIN Q24336 387 23 -
FFFDVQPKMGTTLRVRARIQIN Q9W0X0 388 23 -
IQIDFEPISGTPMMAKQRVQFN Q9GPH7 387 22 -
IEIDYEPITGTPMVAKQRIQFN Q9U1G3 387 22 -
IIADFEPLSGTLMDAKQRMQYN O02351 387 22 -
TYFKIQPKLGVPLEGKVRIQLN Q9W067 338 22 -
IEIDFEPISGTPMVAKQRIQFN Q9U3U2 387 22 -
TYVYIDPVTGVVLKGVKRLQFN Q9GPH8 398 23 -
VYIDFELMSGTPFQAAKRLQFN Q9VDD3 346 22 -
FYMVVQPSTGIPLEVAARFQVN Q9VM10 355 22 -
MYVIMEPTLGIPLSLRGQLMIS Q9VJA7 830 22 -