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PR01607

Identifier
APYRASEFAMLY  [View Relations]  [View Alignment]  
Accession
PR01607
No. of Motifs
6
Creation Date
31-DEC-2001
Title
Apyrase family signature
Database References

PFAM; PF01009 5_nucleotidase
INTERPRO; IPROO2224 5_nuc
PDB; 1USH
SCOP; 1USH
CATH; 1USH
Literature References
1. SMARTT, C.T., KIM, A.P., GROSSMAN, G.L. AND JAMES, A.A.
The Apyrase gene of the vector mosquito, Aedes aegypti, is expressed 
specifically in the adult female salivary glands.
EXP.PARASITOL. 81 239-248 (1995).
 
2. CHAMPAGNE, D.E., SMARTT, C.T., RIBEIRO, J.M.C. AND JAMES, A.A.
The salivary gland-specific apyrase of the mosquito Aedes aegypti is 
a member of the 5'-nucleotidase family.
PROC.NATL.ACAD.SCI.U.S.A. 92 694-698 (1995).
 
3. LOMBARDO, F., MANLIO, C., SPANOS, L., LOUIS, C., COLUZZI, A. AND ARCA, B.
Promoter sequences of the putative Anopheles gambiae Apyrase confer 
salivary gland expression in Drosophila melanogaster.
J.BIOL.CHEM. 275 23861-23868 (2000).
 
4. KNOFEL, T. AND STRATER, N.
X-ray structure of the Escherichia coli periplasmic 5'-nucleotidase 
containing a dimetal catalytic site.
NAT.STRUCT.BIOL. 6 448-453 (1999).

Documentation
Many pathogens are transmitted by arthropod vectors to vertebrate hosts
through salivary secretions that occur while the vectors are feeding on
blood. Since hematophagy has arisen independently several times in insects,
a large variety of different molecules have evolved to accomplish the same
or similar function.
 
When vascular tissue is damaged, the disrupted cells release ATP and ADP at
high concentration into the extracellular environment, where ADP promotes
platelet activation and aggregation. The activated platelets may in turn 
release in the medium their ADP-containing granules, recruiting additional
platelets to the site of injury. One of the ADP-platelet dependent anti-
aggregation components, required for efficient feeding, is an apyrase with 
ATP-diphosphohydrolase activity [1]. Apyrase acts as an allergen, and its 
function is to inhibit the ADP-induced platelet recruitment and aggregation
by hydrolysing ADP to AMP and inorganic phosphate: 
 
		ATP + 2H2O = AMP + 2PHOSPHATE
 
In addition, levels of apyrase activity correlate positively with decreased
probing time during feeding, leading investigators to suggest that the
enzyme facilitates the speed of locating blood.
 
The gene Apyrase is expressed specifically in the adult female salivary
glands of the mosquito A.aegypti. Expression of this gene is confined to
those lobes of the salivary glands that secrete female-enriched products.
Apyrase protein levels increase after adult emergence, and are not affected
greatly by bloodfeeding [1]. In animals, Apyrase has been found in the
bovine aorta, rat uterus and mammary glands, and human placenta. The enzyme
has been implicated as an inhibitor of platelet aggregation [1]. 
 
Sequence comparisons indicate similarities with a ubiquitous family of
5'-nucleotidases. However, the mosquito protein differs from other members
of the family in lacking a C-terminal hydrophobic domain. This is consistent
with the fact that mosquito apyrase is a secreted salivary protein [2]. 
 
The observation that apyrase is similar to 5'-nucleotidase extends earlier
suggestions that the evolutionary history of the nucleotidase family has
been characterised by substrate specification. An example of the ancestral
state is represented by a bacterial enzyme that combines 5'-nucleotidase,
UDP-sugar hydrolase, and apyrase activities, including an identical region
of 6 amino acid residues, GKYVGR. Accordingly, it has been proposed that
duplications of the broad substrate spectrum ancestral gene were followed 
by divergent selection to produce apyrases, 5'-nucleotidases and UDP-sugar 
hydrolases. It is possible that a gene for a single enzyme such as the 
5'-nucleotidase is the common progenitor for salivary apyrases in the 
various arthropod taxa. The apparent conversion of a gene encoding an 
enzyme involved in a common metabolic event at the cellular level to a gene
involved in the anti-haemostatic response, illustrates one way that this
particular insect has adapted to the challenges of bloodfeeding [2,3].
 
The crystal structure of 5'-nucleotidase from E.coli has been determined 
to 1.7A resolution [4]. The structure sequesters two zinc ions within a 
cleft between two domains, so forming the active site. The dimetal center
and a catalytic Asp-His dyad are the principal components of the catalytic
mechanism [4]. Structure-based sequence comparisons indicate that this
structure provides a model for animal 5'-nucleotidases and related proteins. 
 
APYRASEFAMLY is a 6-element fingerprint that provides a signature for the 
apyrase family. The fingerprint was derived from an initial alignment of 16
sequences: the motifs were drawn from conserved regions spanning virtually
the full alignment length - motif 1 encompasses beta-strand 1; motif 2 spans
strand 10 and alpha-helix 7; motif 3 spans the C-terminus of helix 8 and
strands 11 and 12; motif 4 encodes strands 15 and 16; motif 5 encompasses
strands 20 and 21, and helix 13; and motif 6 spans strand 26 and helix 15.
Six iterations on SPTR40_18f were required to reach convergence, at which
point a true set comprising 51 sequences was identified. Several partial 
matches were also found, all of which are family members that fail to make
significant matches with one or more motifs.
Summary Information
  51 codes involving  6 elements
2 codes involving 5 elements
3 codes involving 4 elements
15 codes involving 3 elements
8 codes involving 2 elements
Composite Feature Index
6515151515151
5022222
4323211
31169559
2133045
123456
True Positives
5NTD_BOVIN    5NTD_DISOM    5NTD_HAEIN    5NTD_HUMAN    
5NTD_LUTLO 5NTD_MOUSE 5NTD_RAT 5NTD_TREPA
5NTD_VIBCH 5NTD_VIBPA APY_AEDAE CN16_ECOLI
CN16_HAEIN CN16_YEREN O24930 O34313
Q97HP6 Q97M47 Q98H62 Q98N00
Q9AFP8 Q9AJV8 Q9CIQ3 Q9CJJ3
Q9CLM8 Q9KE43 Q9KGN2 Q9KP17
Q9R2Z2 Q9R369 Q9RN34 Q9RN35
Q9RN36 Q9RN37 Q9RN38 Q9RN39
Q9RN40 Q9RN41 Q9RQT7 Q9RTM4
Q9TW03 Q9U9I6 Q9UB34 Q9V824
Q9V825 Q9X2J1 Q9X6T9 Q9ZMW9
USHA_ECOLI USHA_SALTY YHCR_BACSU
True Positive Partials
Codes involving 5 elements
Q98RF4 Q9VZ33
Codes involving 4 elements
Q9K7B3 Q9KPF2 Q9S2I8
Codes involving 3 elements
O29385 O32133 O67671 Q05700
Q55910 Q99VF3 Q99X70 Q99XE9
Q9CJ29 Q9D3Z8 Q9D469 Q9HPW1
Q9KM44 Q9L4N0 Q9RX10
Codes involving 2 elements
P72177 P72939 Q9A0A2 Q9CGK2
Q9HPZ0 Q9KZU9 Q9V5N4 Q9VZ32
Sequence Titles
5NTD_BOVIN  5'-nucleotidase precursor (EC 3.1.3.5) (Ecto-5'-nucleotidase) (5'-NT) (CD73 antigen) - Bos taurus (Bovine). 
5NTD_DISOM 5'-nucleotidase precursor (EC 3.1.3.5) (Ecto-nucleotidase) - Discopyge ommata (Electric ray).
5NTD_HAEIN Probable 5'-nucleotidase precursor (EC 3.1.3.5) - Haemophilus influenzae.
5NTD_HUMAN 5'-nucleotidase precursor (EC 3.1.3.5) (Ecto-5'-nucleotidase) (5'-NT) (CD73 antigen) - Homo sapiens (Human).
5NTD_LUTLO 5'-nucleotidase precursor (EC 3.1.3.5) - Lutzomyia longipalpis (Sand fly).
5NTD_MOUSE 5'-nucleotidase precursor (EC 3.1.3.5) (Ecto-5'-nucleotidase) (5'-NT) (CD73 antigen) - Mus musculus (Mouse).
5NTD_RAT 5'-nucleotidase precursor (EC 3.1.3.5) (Ecto-5'-nucleotidase) (5'-NT) (CD73 antigen) - Rattus norvegicus (Rat).
5NTD_TREPA Probable 5'-nucleotidase precursor (EC 3.1.3.5) - Treponema pallidum.
5NTD_VIBCH 5'-nucleotidase precursor (EC 3.1.3.5) - Vibrio cholerae.
5NTD_VIBPA 5'-nucleotidase precursor (EC 3.1.3.5) - Vibrio parahaemolyticus.
APY_AEDAE Apyrase precursor (EC 3.6.1.5) (ATP-diphosphatase) (Adenosine diphosphatase) (ADPASE) (ATP-diphosphohydrolase) (Allergen Aed a 1) - Aedes aegypti (Yellowfever mosquito).
CN16_ECOLI 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor (EC 3.1.4.16) - Escherichia coli.
CN16_HAEIN 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor (EC 3.1.4.16) - Haemophilus influenzae.
CN16_YEREN 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor (EC 3.1.4.16) - Yersinia enterocolitica.
O24930 2',3'-CYCLIC-NUCLEOTIDE 2'-PHOSPHODIESTERASE (CPDB) - Helicobacter pylori (Campylobacter pylori).
O34313 YFKN PROTEIN - Bacillus subtilis.
Q97HP6 5'-NUCLEOTIDASE/2',3'-CYCLIC PHOSPHODIESTERASE RELATED ENZYME - Clostridium acetobutylicum.
Q97M47 2,3-CYCLIC-NUCLEOTIDE 2'PHOSPHODIESTERASE (DUPLICATION) - Clostridium acetobutylicum.
Q98H62 5'-NUCLEOTIDASE (EC 3.1.3.5) - Rhizobium loti (Mesorhizobium loti).
Q98N00 PROBABLE MULTIFUNCTIONAL PHOSPHOESTERASE - Rhizobium loti (Mesorhizobium loti).
Q9AFP8 UDP-SUGAR HYDROLASE - Shigella flexneri.
Q9AJV8 USHA, PROBABLE PERIPLASMIC UDP-SUGAR HYDROLASE - Shigella flexneri.
Q9CIQ3 PHOSPHATASE - Lactococcus lactis (subsp. lactis) (Streptococcus lactis).
Q9CJJ3 CPDB - Pasteurella multocida.
Q9CLM8 HYPOTHETICAL PROTEIN PM1193 - Pasteurella multocida.
Q9KE43 BH1015 PROTEIN - Bacillus halodurans.
Q9KGN2 NUCLEOTIDASE PRECURSOR - Bacillus halodurans.
Q9KP17 2`,3`-CYCLIC-NUCLEOTIDE 2`-PHOSPHODIESTERASE - Vibrio cholerae.
Q9R2Z2 UDP-SUGAR HYDROLASE - Salmonella enterica.
Q9R369 UDP-SUGAR HYDROLASE - Salmonella enterica.
Q9RN34 UDP-SUGAR HYDROLASE - Salmonella enterica.
Q9RN35 UDP-SUGAR HYDROLASE - Salmonella enterica.
Q9RN36 UDP-SUGAR HYDROLASE - Salmonella enterica.
Q9RN37 UDP-SUGAR HYDROLASE - Salmonella pullorum.
Q9RN38 UDP-SUGAR HYDROLASE - Salmonella enterica.
Q9RN39 UDP-SUGAR HYDROLASE - Salmonella enterica.
Q9RN40 UDP-SUGAR HYDROLASE - Salmonella gallinarum.
Q9RN41 UDP-SUGAR HYDROLASE - Salmonella enterica.
Q9RQT7 UDP-SUGAR HYDROLASE PRECURSOR - Enterobacter aerogenes (Aerobacter aerogenes).
Q9RTM4 2`,3`-CYCLIC-NUCLEOTIDE 2`-PHOSPHODIESTERASE - Deinococcus radiodurans.
Q9TW03 PUTATIVE APYRASE PRECURSOR (EC 3.6.1.5) - Anopheles gambiae (African malaria mosquito).
Q9U9I6 CHRYSOPTIN PRECURSOR - Chrysops sp.
Q9UB34 PUTATIVE 5'-NUCLEOTIDASE PRECURSOR (EC 3.1.3.5) - Anopheles gambiae (African malaria mosquito).
Q9V824 CG4827 PROTEIN - Drosophila melanogaster (Fruit fly).
Q9V825 CG4837 PROTEIN - Drosophila melanogaster (Fruit fly).
Q9X2J1 UDP-SUGAR HYDROLASE - Thermotoga maritima.
Q9X6T9 5'-NUCLEOTIDASE NUCA PRECURSOR - Haemophilus influenzae.
Q9ZMW9 2',3'-CYCLIC-NUCLEOTIDE 2'-PHOSPHODIESTERASE - Helicobacter pylori J99 (Campylobacter pylori J99).
USHA_ECOLI Protein ushA precursor [Includes: UDP-sugar hydrolase (EC 3.6.1.45) (UDP-sugar diphosphatase) (UDP-sugar pyrophosphatase); 5'-nucleotidase (EC 3.1.3.5) (5'-NT)] - Escherichia coli.
USHA_SALTY Silent protein ushA(0) precursor - Salmonella typhimurium.
YHCR_BACSU Hypothetical protein yhcR precursor - Bacillus subtilis.

Q98RF4 5'-NUCLEOTIDASE PRECURSOR (EC 3.1.3.5) - Mycoplasma pulmonis.
Q9VZ33 CG1961 PROTEIN - Drosophila melanogaster (Fruit fly).

Q9K7B3 BH3453 PROTEIN - Bacillus halodurans.
Q9KPF2 2`,3`-CYCLIC-NUCLEOTIDE 2`-PHOSPHODIESTERASE, PUTATIVE - Vibrio cholerae.
Q9S2I8 PUTATIVE NUCLEOTIDASE - Streptomyces coelicolor.

O29385 5'-NUCLEOTIDASE (NT5) - Archaeoglobus fulgidus.
O32133 YUND PROTEIN - Bacillus subtilis.
O67671 SULFUR OXIDATION PROTEIN SOXB - Aquifex aeolicus.
Q05700 ALKALINE PHOSPHATASE - Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2).
Q55910 HYPOTHETICAL 55.3 KDA PROTEIN - Synechocystis sp. (strain PCC 6803).
Q99VF3 HYPOTHETICAL PROTEIN SA0784 - Staphylococcus aureus subsp. aureus N315.
Q99X70 SA0140 PROTEIN - Staphylococcus aureus subsp. aureus N315.
Q99XE9 SA0022 PROTEIN - Staphylococcus aureus subsp. aureus N315.
Q9CJ29 HYPOTHETICAL PROTEIN YBIB - Lactococcus lactis (subsp. lactis) (Streptococcus lactis).
Q9D3Z8 4933425L06RIK PROTEIN - Mus musculus (Mouse).
Q9D469 4933425L06RIK PROTEIN - Mus musculus (Mouse).
Q9HPW1 2',3'-CYCLIC-NUCLEOTIDE 2'-PHOSPHODIESTERASE - Halobacterium sp. (strain NRC-1).
Q9KM44 5`-NUCLEOTIDASE, PUTATIVE - Vibrio cholerae.
Q9L4N0 CYCLO-NUCLEOTIDE PHOSPHODIESTERASE, PUTATIVE - Streptococcus equisimilis.
Q9RX10 5`-NUCLEOTIDASE FAMILY PROTEIN - Deinococcus radiodurans.

P72177 SOXB PROTEIN - Paracoccus denitrificans.
P72939 ALKALINE PHOSPHATASE - Synechocystis sp. (strain PCC 6803).
Q9A0A2 PUTATIVE SECRETED 5'-NUCLEOTIDASE - Streptococcus pyogenes.
Q9CGK2 NUCLEOTIDASE - Lactococcus lactis (subsp. lactis) (Streptococcus lactis).
Q9HPZ0 UDP-SUGAR HYDROLASE - Halobacterium sp. (strain NRC-1).
Q9KZU9 PUTATIVE SECRETED 5'-NUCLEOTIDASE - Streptomyces coelicolor.
Q9V5N4 HYPOTHETICAL CG11883 PROTEIN - Drosophila melanogaster (Fruit fly).
Q9VZ32 CG11126 PROTEIN - Drosophila melanogaster (Fruit fly).
Scan History
SPTR40_18f 6  100  NSINGLE    
Initial Motifs
Motif 1  width=19
Element Seqn Id St Int Rpt
YKITILHTNDHHGHFWRSE USHA_SALTY 32 32 -
YKITVLHTNDHHGHFWRNE USHA_ECOLI 32 32 -
YKLTVLHTNDHHGRFWQNK 5NTD_VIBPA 36 36 -
WELTILHTNDVHSRLEQTS 5NTD_BOVIN 27 27 -
WELTILHTNDVHSRLEQTS 5NTD_HUMAN 27 27 -
FQLTILHTNDVHARVEETN 5NTD_DISOM 30 30 -
YEIIILHTNDMHARFDQTN 5NTD_LUTLO 30 30 -
FPLSIVHINDFHARFEQTD Q9U9I6 34 34 -
FPLTIIHMNDLHARFAETS Q9TW03 37 37 -
FPLTLIHINDLHARFEETN APY_AEDAE 38 38 -
VELSILHINDHHSYLEPHE 5NTD_HAEIN 35 35 -
FPLTLIHINDLHARFDETN Q9UB34 34 34 -
VDLRIMETTDLHSNMMDFD CN16_ECOLI 22 22 -
VDLRVLETTDLHSNMMDFD CN16_YEREN 27 27 -
VDLRIVATTDVHSFLTDFD CN16_HAEIN 32 32 -
VPLRILSMNDLHGKIDQQY YHCR_BACSU 588 588 -

Motif 2 width=18
Element Seqn Id St Int Rpt
EKPDVIIATTHMGHYDNG USHA_SALTY 207 156 -
EKPDIIIAATHMGHYDNG USHA_ECOLI 207 156 -
ENPDLIFAVTHMGHYENG 5NTD_VIBPA 211 156 -
LNVNKIIALGHSGFEVDK 5NTD_BOVIN 210 164 -
LNVNKIIALGHSGFEMDK 5NTD_HUMAN 210 164 -
QGIDKIIALGHSGFETDK 5NTD_DISOM 211 162 -
ENAEIIIVVGHSGLIKDR 5NTD_LUTLO 217 168 -
EKVDIVIVLSHIGLDHDY Q9U9I6 214 161 -
RDVNIILVLSHCGLEVDK Q9TW03 219 163 -
DKIDIIVVLSHCSYEEDK APY_AEDAE 223 166 -
QGINKIILLSHAGSEKNI 5NTD_HAEIN 217 163 -
KNVNIIVVLSHCGLDGDK Q9UB34 219 166 -
KGADVVVVLAHSGLSADP CN16_ECOLI 215 174 -
QGANLVVAIPHSGLSSDP CN16_YEREN 220 174 -
KGADIVVALAHTGPSDEP CN16_HAEIN 225 174 -
KGVKAIAVLAHMSAEQNG YHCR_BACSU 782 175 -

Motif 3 width=24
Element Seqn Id St Int Rpt
RSLPAGSLAMIVGGHSQDPVCMAS USHA_SALTY 238 13 -
RALPAGSLAMIVGGHSQDPVCMAA USHA_ECOLI 238 13 -
RYLNEGDLDMIVGGHSQEPVCMEG 5NTD_VIBPA 242 13 -
IAQKVKGVDVVVGGHSNTFLYTGN 5NTD_BOVIN 229 1 -
IAQKVRGVDVVVGGHSNTFLYTGN 5NTD_HUMAN 229 1 -
IAQKVRGVDVVVGGHSNTFLYTGK 5NTD_DISOM 230 1 -
IAEKCPLVDIIVGGHSHTFLYTGS 5NTD_LUTLO 236 1 -
AQQAGDYIDAIIGGHSHSFLWTGE Q9U9I6 234 2 -
ALEAGDDVDVIIGGHSHSFLFPNA Q9TW03 239 2 -
AAEAGDDIDVIVGAHSHSFLYSPD APY_AEDAE 243 2 -
IAQKVNDIDVIVTGDSHYLYGNDE 5NTD_HAEIN 236 1 -
AEEAGDLIDVIVGAHSHSLLLNKD Q9UB34 239 2 -
YLSEIPGVNAIMFGHAHAVFPGKD CN16_ECOLI 243 10 -
YLSQVPGIDAIMFGHAHAVFPSKD CN16_YEREN 248 10 -
YLADVPHIDAVIFGHSHRLFPNKE CN16_HAEIN 253 10 -
ANKTDSEIDVIFAAHNHQVVNGEV YHCR_BACSU 810 10 -

Motif 4 width=21
Element Seqn Id St Int Rpt
IWIVQAHEWGKYVGRADFEFR USHA_SALTY 283 21 -
IWIVQAHEWGKYVGRADFEFR USHA_ECOLI 283 21 -
TYIVQAHEWGKYVGRADYEFR 5NTD_VIBPA 287 21 -
VPVVQAYAFGKYLGYLKVEFD 5NTD_BOVIN 275 22 -
VPVVQAYAFGKYLGYLKIEFD 5NTD_HUMAN 275 22 -
IPVVQAYAYGKYLGYLKLTFD 5NTD_DISOM 276 22 -
VPIVQAYCFTKYLGYFKVTIN 5NTD_LUTLO 282 22 -
VLIVQASAFARYVGNITLYFD Q9U9I6 281 23 -
ILIVQAYAYGKYVGRLTAYFD Q9TW03 289 26 -
IPIVQAKSFGKYVGRLTLYFD APY_AEDAE 293 26 -
VFVMEGWAYSAVVGDLGVKFS 5NTD_HAEIN 283 23 -
VLITQARSFGKYVGRLTVNFD Q9UB34 290 27 -
VPAVMPGMWGDHLGVVDLQLS CN16_ECOLI 283 16 -
IPAVMPGQWGDHLGVVDFVLN CN16_YEREN 288 16 -
IPESMAGYWANNISVVDLGLT CN16_HAEIN 293 16 -
KLIVQAFEYGKAIGVVDVEID YHCR_BACSU 836 2 -

Motif 5 width=24
Element Seqn Id St Int Rpt
DITYKSVLKVQPFGNIVVYADMSG USHA_SALTY 417 113 -
DISYKNVLKVQPFGNVVVYADMTG USHA_ECOLI 417 113 -
DITYKDVLTVQPFGNMVSYVDMSG 5NTD_VIBPA 420 112 -
TITWENLAAVLPFGGTFDLVQLKG 5NTD_BOVIN 405 109 -
TITWENLAAVLPFGGTFDLVQLKG 5NTD_HUMAN 405 109 -
TIQVDSLLAVLPFGSTIDLLEVYG 5NTD_DISOM 405 108 -
SITRLELDNVLPFGNALYVVKVPG 5NTD_LUTLO 415 112 -
NVTVSQIITMAPFENTVDTFDLSG Q9U9I6 406 104 -
DITNEEAIGASPFSNTVDLLTLRG Q9TW03 408 98 -
KITNGDIIEAAPFGSTADLIRLKG APY_AEDAE 412 98 -
NVTFNDAYTFLPFGNTLYTYKMEG 5NTD_HAEIN 444 140 -
DITNGLAIEAAPYGSSVDMIKLSG Q9UB34 409 98 -
QLTFRNAADLYLYPNTLIVVKASG CN16_ECOLI 428 124 -
ELTFRNAADLYLYPNTLVVVKASG CN16_YEREN 433 124 -
KLTFRNAADLYLYPNTLVVVKATG CN16_HAEIN 438 124 -
PITWGDLYNIQPFGNVLTKLEIKG YHCR_BACSU 953 96 -

Motif 6 width=20
Element Seqn Id St Int Rpt
PVDPAKTYRMATLSFNATGG USHA_SALTY 484 43 -
PVDPAKTYRMATLNFNATGG USHA_ECOLI 484 43 -
QLRLDGRYRFTVPSYNASGG 5NTD_VIBPA 487 43 -
PLRMDKVYKVILPSFLVSGG 5NTD_BOVIN 486 57 -
PLKMDEVYKVILPNFLANGG 5NTD_HUMAN 486 57 -
PLLDNKIYKIVTNSYIAEGG 5NTD_DISOM 486 57 -
PLRNKKTYNVIMDSFMKDGG 5NTD_LUTLO 498 59 -
PLDPEETYKIVTASFLANGG Q9U9I6 490 60 -
PLNRTANYRVVTMSFIATGK Q9TW03 488 56 -
PLDKQAEYYIVVPSYLADGK APY_AEDAE 494 58 -
PIDDNKRYLVGTNAYVAGGK 5NTD_HAEIN 526 58 -
ALKKDQIYYVAVPSYLADGK Q9UB34 487 54 -
PIDPNAMFLVATNNYRAYGG CN16_ECOLI 530 78 -
PIDPQATFLIGTNNYRAYSG CN16_YEREN 535 78 -
PVDPKAEFLIATNNYRAYGN CN16_HAEIN 540 78 -
EIQPDATYTLTVNNFMATAT YHCR_BACSU 1021 44 -
Final Motifs
Motif 1  width=19
Element Seqn Id St Int Rpt
YKITILHTNDHHGHFWRSE Q9R2Z2 32 32 -
YKITILHTNDHHGHFWRSE Q9R369 32 32 -
YKITILHTNDHHGHFWRSE Q9RN34 32 32 -
YKITILHTNDHHGHFWRSE Q9RN35 32 32 -
YKITILHTNDHHGHFWRSE Q9RN36 32 32 -
YKITILHTNDHHGHFWRSE Q9RN37 32 32 -
YKITILHTNDHHGHFWRSE Q9RN38 32 32 -
YKITILHTNDHHGHFWRSE Q9RN40 32 32 -
YKITILHTNDHHGHFWRSE USHA_SALTY 32 32 -
YKITILHTNDHHGHFWRSE Q9RN41 32 32 -
YKITILHTNDHHGHFWRSE Q9RN39 32 32 -
YKITVLHTNDHHGHFWRNE USHA_ECOLI 32 32 -
YKITILHTNDHHGHFWRND Q9RQT7 32 32 -
YKITVLHTNDHHGHFWRNN Q9AFP8 49 49 -
YKITVLHTNDHHGHFWRNN Q9AJV8 32 32 -
YKLTILHTNDHHGRFWQNQ 5NTD_VIBCH 36 36 -
YKLTVLHTNDHHGRFWQNK 5NTD_VIBPA 36 36 -
YNITVLHANDTHGHFWKNS Q9CLM8 29 29 -
WELTILHTNDVHSRLEQTS 5NTD_MOUSE 29 29 -
WELTILHTNDVHSRLEQTS 5NTD_BOVIN 27 27 -
WELTILHTNDVHSRLEQTS 5NTD_HUMAN 27 27 -
FQLTILHTNDVHARVEETN 5NTD_DISOM 30 30 -
WELTIMHTNDVHSRLEQTS 5NTD_RAT 29 29 -
VHLSILATTDIHANMMDYD O34313 43 43 -
YTLNILHFNDWHSRIEGNN Q98H62 26 26 -
YEIIILHTNDMHARFDQTN 5NTD_LUTLO 30 30 -
ARLTILHVNDTHGHAWAFD Q9X2J1 20 20 -
FPLSIVHINDFHARFEQTD Q9U9I6 34 34 -
FELTIIHINDHHSHLEPEP 5NTD_TREPA 32 32 -
TEFIILHNNDMHARFDQTS Q9V825 31 31 -
ERLSIVHTNDLHGRILPNE Q9KGN2 170 170 -
FPLTIIHMNDLHARFAETS Q9TW03 37 37 -
FPLTLIHINDLHARFEETN APY_AEDAE 38 38 -
HELTIVYTNDIHARIDGYG Q9KE43 42 42 -
VELSILHINDHHSYLEPHE 5NTD_HAEIN 35 35 -
VELSILHINDHHSYLEPHE Q9X6T9 35 35 -
AEFIILHNNDMHARFEQTS Q9V824 35 35 -
VDLRILETTDLHTNALGYD Q9RTM4 64 64 -
FPLTLIHINDLHARFDETN Q9UB34 34 34 -
ASLRIIATTDLHSFLTDFD Q9CJJ3 31 31 -
AHLRIMETTDIHVNVLPYD Q98N00 38 38 -
IKLRIVETTDIHTNLMDYD Q9KP17 56 56 -
VDLRIMETTDLHSNMMDFD CN16_ECOLI 22 22 -
VDLRVLETTDLHSNMMDFD CN16_YEREN 27 27 -
VDLRIVATTDVHSFLTDFD CN16_HAEIN 32 32 -
VPLRILSMNDLHGKIDQQY YHCR_BACSU 588 588 -
STISILATSDIHGNVLNYD Q97M47 540 540 -
VKIVFLETSDIHGRLFSYD O24930 21 21 -
EHIVILETSDVHGNIFPVN Q97HP6 6 6 -
VKIVFLETSDIHGRLFSYD Q9ZMW9 21 21 -
MKIRILETSDLHGFVLPTN Q9CIQ3 1 1 -

Motif 2 width=18
Element Seqn Id St Int Rpt
EKPDVIIATTHMGHYDNG Q9R2Z2 207 156 -
EKPDVIIATTHMGHYDNG Q9R369 207 156 -
EKPDVIIATTHMGHYDNG Q9RN34 207 156 -
EKPDVIIATTHMGHYDNG Q9RN35 207 156 -
EKPDVIIATTHMGHYDNG Q9RN36 207 156 -
EKPDVIIATTHMGHYDNG Q9RN37 207 156 -
EKPDVIIATTHMGHYDNG Q9RN38 207 156 -
EKPDVIIATTHMGHYDNG Q9RN40 207 156 -
EKPDVIIATTHMGHYDNG USHA_SALTY 207 156 -
EKPDVIIATTHMGHYDNG Q9RN41 207 156 -
EKTDLIIATTHMGHYDNG Q9RN39 207 156 -
EKPDIIIAATHMGHYDNG USHA_ECOLI 207 156 -
EKPDVILATTHMGHYDNG Q9RQT7 207 156 -
EKPDIIIAATHMGHYDNG Q9AFP8 224 156 -
EKPDIIIAATHMGHYDNG Q9AJV8 207 156 -
EKPDLIIAVTHMGHYQNG 5NTD_VIBCH 211 156 -
ENPDLIFAVTHMGHYENG 5NTD_VIBPA 211 156 -
EKPDIRIALTHMGYYFDG Q9CLM8 204 156 -
LNVNKIIALGHSGFEMDK 5NTD_MOUSE 212 164 -
LNVNKIIALGHSGFEVDK 5NTD_BOVIN 210 164 -
LNVNKIIALGHSGFEMDK 5NTD_HUMAN 210 164 -
QGIDKIIALGHSGFETDK 5NTD_DISOM 211 162 -
LNVNKIIALGHSGFEMDK 5NTD_RAT 212 164 -
EKVNKIIALTHIGHNRDL O34313 862 800 -
QGVNKIIAVTHIGYNRER Q98H62 212 167 -
ENAEIIIVVGHSGLIKDR 5NTD_LUTLO 217 168 -
KQADVVIALAHLDWGEPK Q9X2J1 195 156 -
EKVDIVIVLSHIGLDHDY Q9U9I6 214 161 -
QGVNKIILLSHAGFEKNC 5NTD_TREPA 214 163 -
QGIDIIIALGHSGYEKDM Q9V825 722 672 -
PTVDHVFLLTHIGYGVDR Q9KGN2 341 152 -
RDVNIILVLSHCGLEVDK Q9TW03 219 163 -
DKIDIIVVLSHCSYEEDK APY_AEDAE 223 166 -
EQADVIIALTHIGYGADR Q9KE43 205 144 -
QGINKIILLSHAGSEKNI 5NTD_HAEIN 217 163 -
QGINKIILLSHAGSEKNI Q9X6T9 217 163 -
QGINIIIALGHSGYQKDQ Q9V824 224 170 -
AGADIIVAVAHSGINADY Q9RTM4 262 179 -
KNVNIIVVLSHCGLDGDK Q9UB34 219 166 -
KGADIIIALAHTGPSDEP Q9CJJ3 224 174 -
EGADIVIALSHSGIDVKQ Q98N00 239 182 -
KGADVIVAIPHSGISTDE Q9KP17 249 174 -
KGADVVVVLAHSGLSADP CN16_ECOLI 215 174 -
QGANLVVAIPHSGLSSDP CN16_YEREN 220 174 -
KGADIVVALAHTGPSDEP CN16_HAEIN 225 174 -
KGVKAIAVLAHMSAEQNG YHCR_BACSU 782 175 -
AGANVVIVAAHSGEEGAA Q97M47 729 170 -
GKYDILIGAFHLGREDEK O24930 200 160 -
KKVDIVVVSYHGGFEKNI Q97HP6 190 165 -
GKYDILIGAFHLGREDEK Q9ZMW9 200 160 -
QSVDLLIVAYHGGFERDL Q9CIQ3 186 166 -

Motif 3 width=24
Element Seqn Id St Int Rpt
RSLPAGSLAMIVGGHSQDPVCMAS Q9R2Z2 238 13 -
RSLPAGSLAMIVGGHSQDPVCMAS Q9R369 238 13 -
RSLPAGSLAMIVGGHSQDPVCMAS Q9RN34 238 13 -
RSLPAGSLAMIVGGHSQDPVCMAS Q9RN35 238 13 -
RSLPAGSLAMIVGGHSQDPVCMAS Q9RN36 238 13 -
RSLPAGSLAMIVGGHSQDPVCMAS Q9RN37 238 13 -
RSLPAGSLAMIVGGHSQDPVCMAS Q9RN38 238 13 -
RSLPAGSLAMIVGGHSQDPVCMAS Q9RN40 238 13 -
RSLPAGSLAMIVGGHSQDPVCMAS USHA_SALTY 238 13 -
RNLPAGSLAMIVGGHSQDPVCMAS Q9RN41 238 13 -
RSLPAGSLAMIVGGHSQDPVCMAS Q9RN39 238 13 -
RALPAGSLAMIVGGHSQDPVCMAA USHA_ECOLI 238 13 -
RSLPAGSLAMIVGGHSQDPVCMAS Q9RQT7 238 13 -
RSLPTGSLAMIVGGHSQAPVCMAS Q9AFP8 255 13 -
RSLPTGSLAMIVGGHSQAPVCMAS Q9AJV8 238 13 -
RYLPAGELDMIVGGHSQEPVCMEG 5NTD_VIBCH 242 13 -
RYLNEGDLDMIVGGHSQEPVCMEG 5NTD_VIBPA 242 13 -
RTLDKGAFDLIIGGHTHDTVCIDE Q9CLM8 235 13 -
IAQKVRGVDIVVGGHSNTFLYTGN 5NTD_MOUSE 231 1 -
IAQKVKGVDVVVGGHSNTFLYTGN 5NTD_BOVIN 229 1 -
IAQKVRGVDVVVGGHSNTFLYTGN 5NTD_HUMAN 229 1 -
IAQKVRGVDVVVGGHSNTFLYTGK 5NTD_DISOM 230 1 -
IAQKVRGVDVVVGGHTNTFLYTGN 5NTD_RAT 231 1 -
LAKKVKGIDLIIGGHTHTLVDKME O34313 881 1 -
IIAKIPGVDVVVGGHSHTLLSNTD Q98H62 231 1 -
IAEKCPLVDIIVGGHSHTFLYTGS 5NTD_LUTLO 236 1 -
QLAGVEGIDVVIAGHSHVLGSDVV Q9X2J1 221 8 -
AQQAGDYIDAIIGGHSHSFLWTGE Q9U9I6 234 2 -
IAQNISGIDVIVSGDTHYLLGDES 5NTD_TREPA 233 1 -
IAKRCPDVDIVVGGQSHTFLYSGK Q9V825 741 1 -
IAEQVEGIDLILGGHSHTTLESPV Q9KGN2 360 1 -
ALEAGDDVDVIIGGHSHSFLFPNA Q9TW03 239 2 -
AAEAGDDIDVIVGAHSHSFLYSPD APY_AEDAE 243 2 -
LAEQVDYFDLIIGGHSHTTLTSPQ Q9KE43 224 1 -
IAQKVNDIDVIVTGDSHYLYGNDE 5NTD_HAEIN 236 1 -
IAQKVNDIDVIVTGDSHYLYGNDE Q9X6T9 236 1 -
IAMNCPEVDIVIGGHSHTFLDANQ Q9V824 243 1 -
ELTKVPGIDVVLSGHSHQEFPGPV Q9RTM4 289 9 -
AEEAGDLIDVIVGAHSHSLLLNKD Q9UB34 239 2 -
YLADVKGIDAVIFGHSHRLFPNKE Q9CJJ3 252 10 -
FVAGVDGIDAVFTGHQHLVFPGKK Q98N00 266 9 -
YLTQVKGIDAIAFGHSHAVFPGKD Q9KP17 277 10 -
YLSEIPGVNAIMFGHAHAVFPGKD CN16_ECOLI 243 10 -
YLSQVPGIDAIMFGHAHAVFPSKD CN16_YEREN 248 10 -
YLADVPHIDAVIFGHSHRLFPNKE CN16_HAEIN 253 10 -
ANKTDSEIDVIFAAHNHQVVNGEV YHCR_BACSU 810 10 -
IATNVSGIDAIVAGHAHVTVNDTS Q97M47 757 10 -
LAKKFPQFDIIFAGHEHAVYNTKV O24930 225 7 -
LCNEVDGIDVLLTGHQHREIYGMK Q97HP6 225 17 -
LAKKFPQFDIIFAGHEHAVYNTKV Q9ZMW9 225 7 -
VEEYKDYIDALVTGHQHREIADHL Q9CIQ3 222 18 -

Motif 4 width=21
Element Seqn Id St Int Rpt
IWIVQAHEWGKYVGRADFEFR Q9R2Z2 283 21 -
IWIVQAHEWGKYVGRADFEFR Q9R369 283 21 -
IWIVQAHEWGKYVGRADFEFR Q9RN34 283 21 -
IWIVQAHEWGKYVGRADFEFR Q9RN35 283 21 -
IWIVQAHEWGKYVGRADFEFR Q9RN36 283 21 -
IWIVQAHEWGKYVGRADFEFR Q9RN37 283 21 -
IWIVQAHEWGKYVGRADFEFR Q9RN38 283 21 -
IWIVQAHEWGKYVGRADFEFR Q9RN40 283 21 -
IWIVQAHEWGKYVGRADFEFR USHA_SALTY 283 21 -
IWIVQAHEWGKYVGRADFEFR Q9RN41 283 21 -
IWIVQAHEWGKYVGRADFEFR Q9RN39 283 21 -
IWIVQAHEWGKYVGRADFEFR USHA_ECOLI 283 21 -
IWIVQAHEWGKYVGRADFEFR Q9RQT7 283 21 -
IWIVQAHEWGKYVGQADFEFC Q9AFP8 300 21 -
IWIVQAHEWGKYVGQADFEFC Q9AJV8 283 21 -
TYIVQAYEWGKYVGRADYEFR 5NTD_VIBCH 287 21 -
TYIVQAHEWGKYVGRADYEFR 5NTD_VIBPA 287 21 -
TWIVQAGEWGKYIGRADFEFK Q9CLM8 280 21 -
VPVVQAYAFGKYLGYLKVEFD 5NTD_MOUSE 277 22 -
VPVVQAYAFGKYLGYLKVEFD 5NTD_BOVIN 275 22 -
VPVVQAYAFGKYLGYLKIEFD 5NTD_HUMAN 275 22 -
IPVVQAYAYGKYLGYLKLTFD 5NTD_DISOM 276 22 -
VPVVQAYAFGKYLGYLKVEFD 5NTD_RAT 277 22 -
TIVAQAKEYGQFLGRVDVAFD O34313 912 7 -
VPVVQAASYSKYLGEFKVVFD Q98H62 273 18 -
VPIVQAYCFTKYLGYFKVTIN 5NTD_LUTLO 282 22 -
KIIASAGEYGKYVGRLDLDIE Q9X2J1 247 2 -
VLIVQASAFARYVGNITLYFD Q9U9I6 281 23 -
VYVVEAWEYGKCLGELNVVFD 5NTD_TREPA 280 23 -
VPVVQAYAYTKYLGNLSLEFD Q9V825 787 22 -
TYITQAYEHGKAVGVTYVLFH Q9KGN2 388 4 -
ILIVQAYAYGKYVGRLTAYFD Q9TW03 289 26 -
IPIVQAKSFGKYVGRLTLYFD APY_AEDAE 293 26 -
TPIVQSGANLTNVGKVVLELD Q9KE43 252 4 -
VFVMEGWAYSAVVGDLGVKFS 5NTD_HAEIN 283 23 -
VFVMEGWAYSAVVGDLGVKFS Q9X6T9 283 23 -
VPVVQAYAYTKYLGKIHVQFD Q9V824 295 28 -
KPVVMAGYWGNDLGVVDLQLN Q9RTM4 329 16 -
VLITQARSFGKYVGRLTVNFD Q9UB34 290 27 -
VPESMAGYWGNNISVVDLELA Q9CJJ3 292 16 -
KPAVMGGFWGSHMGLIDLMLE Q98N00 307 17 -
VTAVMPGRWGSHVGVMDLTLE Q9KP17 317 16 -
VPAVMPGMWGDHLGVVDLQLS CN16_ECOLI 283 16 -
IPAVMPGQWGDHLGVVDFVLN CN16_YEREN 288 16 -
IPESMAGYWANNISVVDLGLT CN16_HAEIN 293 16 -
KLIVQAFEYGKAIGVVDVEID YHCR_BACSU 836 2 -
VPVVEPNKWGTFVSQIDITLD Q97M47 789 8 -
VHTIEPGAYGAYLAKGVVVFD O24930 251 2 -
VTIIQPGSSAKNIGKVDIIAE Q97HP6 252 3 -
VHTIEPGAYGAYLAKGVVVFD Q9ZMW9 251 2 -
VPVIQPGYRGAFVGEIELELD Q9CIQ3 248 2 -

Motif 5 width=24
Element Seqn Id St Int Rpt
DITYKSVLKVQPFGNIVVYADMSG Q9R2Z2 417 113 -
DITYKSVLKVQPFGNIVVYADMSG Q9R369 417 113 -
DITYKSVLKVQPFGNIVVYADMSG Q9RN34 417 113 -
DITYKSVLKVQPFGNIVVYADMSG Q9RN35 417 113 -
DITYKSVLKVQPFGNIVVYADMSG Q9RN36 417 113 -
DITYKSVLKVQPFGNIVVYADMSG Q9RN37 417 113 -
DITYKSVLKVQPFGNIVVYADMSG Q9RN38 417 113 -
DITYKSVLKVQPFGNIVVYADMSG Q9RN40 417 113 -
DITYKSVLKVQPFGNIVVYADMSG USHA_SALTY 417 113 -
DITYKSVLKVQPFGNIVVYADMSG Q9RN41 417 113 -
DITYKSVLKVQPFGNIVVYADMSG Q9RN39 417 113 -
DISYKNVLKVQPFGNVVVYADMTG USHA_ECOLI 417 113 -
DITYKDVMKVQPFGNVLTYVDMSG Q9RQT7 417 113 -
NITYKDILKVQPFGNTVVSIDLTG Q9AFP8 434 113 -
NITYKDILKVQPFGNTVVSIDLTG Q9AJV8 417 113 -
DITYKDVLKVQPFGNIVSYVDMNG 5NTD_VIBCH 420 112 -
DITYKDVLTVQPFGNMVSYVDMSG 5NTD_VIBPA 420 112 -
ETTYKDLLTVQPFGNMIATVDFTG Q9CLM8 414 113 -
TITWENLAAVLPFGGTFDLVQLKG 5NTD_MOUSE 407 109 -
TITWENLAAVLPFGGTFDLVQLKG 5NTD_BOVIN 405 109 -
TITWENLAAVLPFGGTFDLVQLKG 5NTD_HUMAN 405 109 -
TIQVDSLLAVLPFGSTIDLLEVYG 5NTD_DISOM 405 108 -
TITWENLAAVLPFGGTFDLVQLKG 5NTD_RAT 407 109 -
DITLGEVLNVMPFGNTLYVADLTG O34313 1035 102 -
TVTMGEVLTVLPFQNTLATFQISG Q98H62 393 99 -
SITRLELDNVLPFGNALYVVKVPG 5NTD_LUTLO 415 112 -
KITVRDILTVLPFGNTLYVLELTG Q9X2J1 376 108 -
NVTVSQIITMAPFENTVDTFDLSG Q9U9I6 406 104 -
EITYNDAYTLLPFSNTLVLVDVSG 5NTD_TREPA 444 143 -
AITEADVVTVLPFSQDLYYTRISG Q9V825 919 111 -
DVTKGDVIAAFPFTNTVIALEITG Q9KGN2 504 95 -
DITNEEAIGASPFSNTVDLLTLRG Q9TW03 408 98 -
KITNGDIIEAAPFGSTADLIRLKG APY_AEDAE 412 98 -
EVTVGDIYRIEPFANEIMLFEMTG Q9KE43 368 95 -
NVTFNDAYTFLPFGNTLYTYKMEG 5NTD_HAEIN 444 140 -
NVTFNDAYTFLPFGNTLYTYKMEG Q9X6T9 444 140 -
VINGATLLAVLPFENNLYVTRILG Q9V824 425 109 -
TLAIKNVADLYVYPNTVQAVLVTG Q9RTM4 474 124 -
DITNGLAIEAAPYGSSVDMIKLSG Q9UB34 409 98 -
ELTFRNAADLYLYPNTLVIVKVSG Q9CJJ3 437 124 -
DIAIKNVADLYLYPNTVRAVEITG Q98N00 452 124 -
ELTFRNAADLYLYPNTLVTMKVSG Q9KP17 462 124 -
QLTFRNAADLYLYPNTLIVVKASG CN16_ECOLI 428 124 -
ELTFRNAADLYLYPNTLVVVKASG CN16_YEREN 433 124 -
KLTFRNAADLYLYPNTLVVVKATG CN16_HAEIN 438 124 -
PITWGDLYNIQPFGNVLTKLEIKG YHCR_BACSU 953 96 -
DVTIKDIMSVYVYENYLYGIKMTG Q97M47 904 94 -
PFKRKDVTYIYKFANTLIGVRITG O24930 379 107 -
KVTMRDIVSNYVYPNTLKVMKVKG Q97HP6 371 98 -
PFKRKDVAYIYKFANTLIGVRITG Q9ZMW9 379 107 -
EISMRSILTNYIYPNTLAVLRVTG Q9CIQ3 365 96 -

Motif 6 width=20
Element Seqn Id St Int Rpt
PVDPAKTYRMATLSFNATGG Q9R2Z2 484 43 -
PVDPAKTYRMATLSFNATGG Q9R369 484 43 -
PVDPAKTYRMATLSFNATGG Q9RN34 484 43 -
PVDPAKTYRMATLSFNATGG Q9RN35 484 43 -
PVDPAKTYRMATLSFNATGG Q9RN36 484 43 -
PVDPAKTYRMATLSFNATGG Q9RN37 484 43 -
PVDPAKTYRMATLSFNATGG Q9RN38 484 43 -
PVDPAKTYRMATLSFNATGG Q9RN40 484 43 -
PVDPAKTYRMATLSFNATGG USHA_SALTY 484 43 -
PVDPAKTYRMATLSFNATGG Q9RN41 484 43 -
PVDPAKTYRMATLSFNATGG Q9RN39 484 43 -
PVDPAKTYRMATLNFNATGG USHA_ECOLI 484 43 -
PVDPAKTYRMATLSFNATGR Q9RQT7 484 43 -
SVDLNKKYRMTTFSFNATGG Q9AFP8 501 43 -
SVDLNKKYRMTTFSFNATGG Q9AJV8 484 43 -
QLRLDATYRFTVPSFNAAGG 5NTD_VIBCH 487 43 -
QLRLDGRYRFTVPSYNASGG 5NTD_VIBPA 487 43 -
ALDLNKTYKVSVPDYCAGGG Q9CLM8 483 45 -
PLEMDKVYKVTLPSYLANGG 5NTD_MOUSE 488 57 -
PLRMDKVYKVILPSFLVSGG 5NTD_BOVIN 486 57 -
PLKMDEVYKVILPNFLANGG 5NTD_HUMAN 486 57 -
PLLDNKIYKIVTNSYIAEGG 5NTD_DISOM 486 57 -
PLEMDKVYKVVLPSYLVNGG 5NTD_RAT 488 57 -
AINTDDTYRVATNNFVGAGG O34313 1113 54 -
PIKPDKDYLVATNNYVRQGG Q98H62 471 54 -
PLRNKKTYNVIMDSFMKDGG 5NTD_LUTLO 498 59 -
PLDPEKKYKVVTNNYMAGGG Q9X2J1 443 43 -
PLDPEETYKIVTASFLANGG Q9U9I6 490 60 -
PVDERAPYRLGVNSYIARGK 5NTD_TREPA 525 57 -
AVDTNGYYGVVVTSFLLNGG Q9V825 1001 58 -
PLDKNKTYTVATNDFLAAGG Q9KGN2 577 49 -
PLNRTANYRVVTMSFIATGK Q9TW03 488 56 -
PLDKQAEYYIVVPSYLADGK APY_AEDAE 494 58 -
PIDEEATYRVAVPDYIGTGG Q9KE43 440 48 -
PIDDNKRYLVGTNAYVAGGK 5NTD_HAEIN 526 58 -
PIDDNKRYLVGTNAYVAGGK Q9X6T9 526 58 -
SINETALYQVIVPQFLLEGG Q9V824 507 58 -
PIDPAAQFVVATNNYRASGG Q9RTM4 575 77 -
ALKKDQIYYVAVPSYLADGK Q9UB34 487 54 -
PVDPKAEFLIATNNYRAYSA Q9CJJ3 539 78 -
PIDPNQKFVVATNNYRAGGG Q98N00 552 76 -
PIDTQQTFLIATNNYRAYSN Q9KP17 564 78 -
PIDPNAMFLVATNNYRAYGG CN16_ECOLI 530 78 -
PIDPQATFLIGTNNYRAYSG CN16_YEREN 535 78 -
PVDPKAEFLIATNNYRAYGN CN16_HAEIN 540 78 -
EIQPDATYTLTVNNFMATAT YHCR_BACSU 1021 44 -
PIKDSDVFTVAINDYRYNGG Q97M47 1005 77 -
PIDPKAIYKLAINNYRFGTL O24930 466 63 -
PVNMEQDYNIALNNYRAAGG Q97HP6 460 65 -
PINPKAVYKLAINNYRFGTL Q9ZMW9 466 63 -
QVKDDEILEIVVNQYRAVGG Q9CIQ3 455 66 -