SPRINT Home UMBER Home Contents Standard Search Advanced Search Relation Search

==SPRINT==> PRINTS View



  selected as


PR01496

Identifier
SHAKERCHANEL  [View Relations]  [View Alignment]  
Accession
PR01496
No. of Motifs
5
Creation Date
26-FEB-2001
Title
Skaker voltage-gated K+ channel family signature
Database References
PRINTS; PR00169 KCHANNEL; PR01491 KVCHANNEL; PR01508 KV11CHANNEL
PRINTS; PR01509 KV12CHANNEL; PR01510 KV13CHANNEL; PR01511 KV14CHANNEL
PRINTS; PR01512 KV15CHANNEL
Literature References
1. MILLER, C.
An overview of the potassium channel family.
GENOME BIOL. 1(4) 1-5 (2000).
 
2. ASHCROFT, F.M.
Voltage-gated K+ channels.
IN ION CHANNELS AND DISEASE, ACADEMIC PRESS, 2000, PP.97-123.
 
3. SANSOM, M.S.
Putting the parts together.
CURR.BIOL. 9(19) R738-R741 (1999).   
 
4. LITTLETON, J.T. AND GANETZKY, B.
Ion Channels and synaptic organisation: analysis of the Drosophila genome.	
NEURON 26 35-43 (2000).
 
5. CONLEY, E.C. AND BRAMMAR, W.J.
Shaker.
IN THE ION CHANNEL FACTSBOOK, VOLUME IV, ACADEMIC PRESS, 1999, PP.559-614.  

Documentation
Potassium ion (K+) channels are a structurally diverse group of proteins
that facilitate the flow of K+ ions across cell membranes. They are
ubiquitous, being present in virtually all cell types. Activation of K+
channels tends to hyperpolarise cells, reducing the membrane's electrical
resistance, dampening nervous activity. In eukaryotic cells, K+ channels
are involved in neural signalling and generation of the cardiac rhythm, and
act as effectors in signal transduction pathways involving G protein-
coupled receptors (GPCRs). In prokaryotic cells, they play a role in the
maintenance of ionic homeostasis [1].
   
Structurally, Kv channels belong to the subfamily of K+ channels whose
subunits contain 6 transmembrane (TM) domains: these are the voltage-
gated K+ (Kv) channels, the KCNQ channels, the EAG-like K+ channels and
3 kinds of Ca2+-activated K+ channels (BK, IK and SK) [2]. All K+
channels share a characteristic sequence feature: a TMxTVGYG motif
that resides between the 2 C-terminal membrane spanning helices, and
forms the K+-selective pore domain [1-2].
 
The Kv family can be divided into 4 subfamilies on the basis of sequence
similarity and function: Shaker (Kv1), Shab (Kv2), Shaw (Kv3) and Shal 
(Kv4). All consist of pore-forming alpha subunits that associate with 
different types of beta subunit. To form a functional K+ channel pore,
4 alpha subunits and 4 beta subunits are required. The alpha subunits
have 6 well-conserved TM domains, a pore loop region and variable length
N- and C-termini. TM domains 5/6 and the loop region form the K+ 
channel pore through which the K+ ions pass [3]. 
 
The first Shaker (Kv1) sequence was found in Drosophila. Several vertebrate
K+ channels with similar amino acid sequences were subsequently found and,
together with the Drosophila Shaker channel, now constitute the Shaker (Kv1)
family. These channels are mostly expressed in the brain, but can also be
found in non-excitable cells, such as lymphocytes [4,5].  
 
SHAKERCHANEL is a 5-element fingerprint that provides a signature for the
Skaker voltage-gated K+ channel family. The fingerprint was derived from an
initial alignment of 14 sequences: the motifs were drawn from conserved
regions spanning the N-terminal half of the alignment: motifs 1-3 reside in
the N-terminal domain; motif 4 spans the N-terminus of TM domain 1; and 
motif 5 spans the C-terminus of TM domain 1. Three iterations on SPTR39_15f
were required to reach convergence, at which point a true set comprising 41
sequences was identified. Several partial matches were also found, all of
which are members of the Shaker family or are closely related potassium 
channels that fail to make significant matches with 2 or more motifs.
Summary Information
  41 codes involving  5 elements
0 codes involving 4 elements
3 codes involving 3 elements
7 codes involving 2 elements
Composite Feature Index
54141414141
400000
313023
212065
12345
True Positives
CIK1_DROME    CIK1_HUMAN    CIK1_MOUSE    CIK1_RAT      
CIK2_DROME CIK2_HUMAN CIK2_MOUSE CIK2_XENLA
CIK3_HUMAN CIK3_MOUSE CIK3_RAT CIK4_BOVIN
CIK4_DROME CIK4_HUMAN CIK4_MOUSE CIK4_MUSPF
CIK4_RAT CIK5_HUMAN CIK5_MOUSE CIK5_MUSPF
CIK5_RABIT CIK5_RAT CIK6_HUMAN CIK6_RAT
O61335 Q16322 Q16968 Q25376
Q26597 Q28293 Q28656 Q61923
Q91781 Q9I829 Q9I830 Q9MYX3
Q9PWM8 Q9TS07 Q9XXX0 Q9YGX8
Q9Z1R6
True Positive Partials
Codes involving 3 elements
O70259 Q26095 Q28649
Codes involving 2 elements
CIKE_RAT CIKG_HUMAN CIKG_RAT O18476
O76457 Q09658 Q9VWZ9
Sequence Titles
CIK1_DROME  VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN, ADULT (SHAKER-ALPHA) - Drosophila melanogaster (Fruit fly). 
CIK1_HUMAN VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.1 (HUKI) (HBK1) - Homo sapiens (Human).
CIK1_MOUSE VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.1 (MK1) (MBK1) - Mus musculus (Mouse).
CIK1_RAT VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.1 (IA) (RBK1) (RCK1) - Rattus norvegicus (Rat).
CIK2_DROME VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN, LATE POPULATION (SHAKER- BETA) - Drosophila melanogaster (Fruit fly).
CIK2_HUMAN VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.2 (RBK2) (HBK5) (NGK1) (MK2) (HUKIV) - Homo sapiens (Human).
CIK2_MOUSE VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.2 (RBK2) (RCK5) (NGK1) (MK2) (HUKIV) - Mus musculus (Mouse), and Rattus norvegicus (Rat).
CIK2_XENLA VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.2 (XSHA2) - Xenopus laevis (African clawed frog).
CIK3_HUMAN VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.3 (HPCN3) (HGK5) (HUKIII) (HLK3) - Homo sapiens (Human).
CIK3_MOUSE VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.3 (MK3) - Mus musculus (Mouse).
CIK3_RAT VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.3 (RGK5) (RCK3) (KV3) - Rattus norvegicus (Rat).
CIK4_BOVIN VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.4 (BAK4) - Bos taurus (Bovine).
CIK4_DROME VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN, LARVAL (SHAKER-EPSILON) - Drosophila melanogaster (Fruit fly).
CIK4_HUMAN VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.4 (HK1) (HPCN2) (HBK4) (HUKII) - Homo sapiens (Human).
CIK4_MOUSE VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.4 - Mus musculus (Mouse).
CIK4_MUSPF VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.4 (FK1) - Mustela putorius furo (Ferret).
CIK4_RAT VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.4 (RCK4) (RHK1) (RK4) - Rattus norvegicus (Rat).
CIK5_HUMAN VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.5 (HK2) (HPCN1) - Homo sapiens (Human).
CIK5_MOUSE VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.5 (KV1-5) - Mus musculus (Mouse).
CIK5_MUSPF VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.5 - Mustela putorius furo (Ferret).
CIK5_RABIT VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.5 - Oryctolagus cuniculus (Rabbit).
CIK5_RAT VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.5 (KV1) (RCK7) - Rattus norvegicus (Rat).
CIK6_HUMAN VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.6 (HBK2) - Homo sapiens (Human).
CIK6_RAT VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.6 (RCK2) (KV2) - Rattus norvegicus (Rat).
O61335 POTASSIUM CHANNEL - Panulirus interruptus (California spiny lobster).
Q16322 CYCLIC GMP GATED POTASSIUM CHANNEL - Homo sapiens (Human).
Q16968 POTASSIUM CHANNEL - Aplysia californica (California sea hare).
Q25376 VOLTAGE-DEPENDENT POTASSIUM CHANNEL SQKV1A - Loligo opalescens (California market squid).
Q26597 POTASSIUM CHANNEL PROTEIN - Schistosoma mansoni (Blood fluke).
Q28293 DELAYED RECTIFIER K+ CHANNEL - Canis familiaris (Dog).
Q28656 GLIBENCLAMIDE-SENSITIVE VOLTAGE-GATED POTASSIUM CHANNEL - Oryctolagus cuniculus (Rabbit).
Q61923 MURINE POTASSIUM CHANNEL PROTEIN - Mus musculus (Mouse).
Q91781 POTASSIUM CHANNEL - Xenopus laevis (African clawed frog).
Q9I829 SHAKER-RELATED POTASSIUM CHANNEL TSHA2 - Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
Q9I830 SHAKER-RELATED POTASSIUM CHANNEL TSHA1 - Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
Q9MYX3 POTASSIUM CHANNEL SUBUNIT KV 1.2 - Oryctolagus cuniculus (Rabbit).
Q9PWM8 POTASSIUM CHANNEL SHAKER ALPHA SUBUNIT VARIANT CKV1.4(M) - Gallus gallus (Chicken).
Q9TS07 BAK5=DELAYED RECTIFIER POTASSIUM CHANNEL KV1.5 HOMOLOG - Bos taurus (Bovine).
Q9XXX0 TUKVI - Halocynthia roretzi (Sea squirt).
Q9YGX8 POTASSIUM CHANNEL SHAKER CKV1.4 - Gallus gallus (Chicken).
Q9Z1R6 VENTRICULAR POTASSIUM CHANNEL KV1.5 - Mus musculus (Mouse).

O70259 VOLTAGE-GATED POTASSIUM CHANNEL KV1.7 - Mus musculus (Mouse).
Q26095 POTASSIUM CHANNEL HOMOLOG - Polyorchis penicillatus (Hydromedusa).
Q28649 CGMP-GATED POTASSIUM CHANNEL - Oryctolagus cuniculus (Rabbit).

CIKE_RAT VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV3.2 (KSHIIIA) - Rattus norvegicus (Rat).
CIKG_HUMAN VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV3.4 (KSHIIIC) - Homo sapiens (Human).
CIKG_RAT VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV3.4 (RAW3) - Rattus norvegicus (Rat).
O18476 KV2 VOLTAGE-GATED POTASSIUM CHANNEL - Loligo pealeii (Longfin squid).
O76457 SHAW POTASSIUM CHANNEL KV3.1A - Aplysia californica (California sea hare).
Q09658 PUTATIVE POTASSIUM CHANNEL PROTEIN ZK1321.2 IN CHROMOSOME II - Caenorhabditis elegans.
Q9VWZ9 SH GENE PRODUCT - Drosophila melanogaster (Fruit fly).
Scan History
SPTR39_15f 3  60   NSINGLE    
Initial Motifs
Motif 1  width=12
Element Seqn Id St Int Rpt
PKKRMRYFDPLR CIK1_HUMAN 66 66 -
PKKRMRYFDPLR CIK1_RAT 66 66 -
PKKRMRYFDPLR CIK1_MOUSE 66 66 -
PKRRMRYFDPLR CIK3_MOUSE 86 86 -
PKRRMRYFDPLR CIK3_RAT 83 83 -
PKKRMRYFDPLR CIK2_HUMAN 62 62 -
PKKRMRYFDPLR CIK2_XENLA 62 62 -
PEKRTQYFDPLR CIK4_BOVIN 213 213 -
PEKRTQYFDPLR CIK4_MOUSE 206 206 -
PEKRTQYFDPLR CIK4_MUSPF 206 206 -
PAKRLRYFDPLR CIK5_RABIT 133 133 -
PVKRLRYFDPLR CIK5_MOUSE 140 140 -
PGRRVRFFDPLR CIK6_HUMAN 70 70 -
PGRRVRFFDPLR CIK6_RAT 70 70 -

Motif 2 width=11
Element Seqn Id St Int Rpt
YFFDRNRPSFD CIK1_HUMAN 80 2 -
YFFDRNRPSFD CIK1_RAT 80 2 -
YFFDRNRPSFD CIK1_MOUSE 80 2 -
YFFDRNRPSFD CIK3_MOUSE 100 2 -
YFFDRNRPSFD CIK3_RAT 97 2 -
YFFDRNRPSFD CIK2_HUMAN 76 2 -
YFFDRNRPSFD CIK2_XENLA 76 2 -
YFFDRNRPSFD CIK4_BOVIN 227 2 -
YFFDRNRPSFD CIK4_MOUSE 220 2 -
YFFDRNRPSFD CIK4_MUSPF 220 2 -
YFFDRNRPSFD CIK5_RABIT 147 2 -
YFFDRNRPSFD CIK5_MOUSE 154 2 -
YFFDRNRPSFD CIK6_HUMAN 84 2 -
YFFDRNRPSFD CIK6_RAT 84 2 -

Motif 3 width=12
Element Seqn Id St Int Rpt
GEEAMEKFREDE CIK1_HUMAN 123 32 -
GEEAMEKFREDE CIK1_RAT 123 32 -
GEEAMEKFREDE CIK1_MOUSE 123 32 -
GEEAMEKFREDE CIK3_MOUSE 143 32 -
GEEAMEKFREDE CIK3_RAT 140 32 -
GEEAMEMFREDE CIK2_HUMAN 119 32 -
GEEAMEIFREDE CIK2_XENLA 119 32 -
GEEALLKFREDE CIK4_BOVIN 270 32 -
GEEALLKFREDE CIK4_MOUSE 263 32 -
GEEALLKFREDE CIK4_MUSPF 263 32 -
GDEAMERFREDE CIK5_RABIT 190 32 -
GDEAMERFREDE CIK5_MOUSE 197 32 -
GDEALAAFREDE CIK6_HUMAN 127 32 -
GDEALAAFREDE CIK6_RAT 127 32 -

Motif 4 width=17
Element Seqn Id St Int Rpt
FEYPESSGPARVIAIVS CIK1_HUMAN 157 22 -
FEYPESSGPARVIAIVS CIK1_RAT 157 22 -
FEYPESSGPARVIAIVS CIK1_MOUSE 157 22 -
FEYPESSGPARGIAIVS CIK3_MOUSE 177 22 -
FEYPESSGPARGIAIVS CIK3_RAT 174 22 -
FEYPESSGPARIIAIVS CIK2_HUMAN 153 22 -
FEYPESSGPARIIAIIS CIK2_XENLA 153 22 -
FEYPESSSPARGIAIVS CIK4_BOVIN 305 23 -
FEYPESSSPARGIAIVS CIK4_MOUSE 298 23 -
FEYPESSSPARGIAIVS CIK4_MUSPF 298 23 -
FEYPESSGSARAIAIVS CIK5_RABIT 224 22 -
FEYPESSGSARAIAIVS CIK5_MOUSE 231 22 -
FEYPESSGPARGIAIVS CIK6_HUMAN 164 25 -
FEYPESSGPARGIAIVS CIK6_RAT 164 25 -

Motif 5 width=12
Element Seqn Id St Int Rpt
SIVIFCLETLPE CIK1_HUMAN 180 6 -
SIVIFCLETLPE CIK1_RAT 180 6 -
SIVIFCLETLPE CIK1_MOUSE 180 6 -
SIVIFCLETLPE CIK3_MOUSE 200 6 -
SIVIFCLETLPE CIK3_RAT 197 6 -
SIVSFCLETLPI CIK2_HUMAN 176 6 -
SIVSFCLETLPV CIK2_XENLA 176 6 -
SIVIFCLETLPE CIK4_BOVIN 328 6 -
SIVIFCLETLPE CIK4_MOUSE 321 6 -
SIVIFCLETLPE CIK4_MUSPF 321 6 -
SIITFCLETLPE CIK5_RABIT 247 6 -
SIITFCLETLPE CIK5_MOUSE 254 6 -
SIVIFCLETLPQ CIK6_HUMAN 187 6 -
SIVIFCLETLPQ CIK6_RAT 187 6 -
Final Motifs
Motif 1  width=12
Element Seqn Id St Int Rpt
PKKRMRYFDPLR CIK1_HUMAN 66 66 -
PKKRMRYFDPLR CIK1_RAT 66 66 -
PKKRMRYFDPLR CIK1_MOUSE 66 66 -
PKRRMRYFDPLR CIK3_HUMAN 81 81 -
PKRRMRYFDPLR CIK3_MOUSE 86 86 -
PKRRMRYFDPLR CIK3_RAT 83 83 -
PKKRMRYFDPLR Q91781 63 63 -
PAKRGRYFDPLR Q9PWM8 221 221 -
PAKRGRYFDPLR Q9YGX8 221 221 -
PKRRMRYFDPVR Q28656 74 74 -
PKKRMRYFDPLR CIK2_HUMAN 62 62 -
PKKRMRYFDPLR Q9MYX3 62 62 -
PKKRMRYFDPLR CIK2_MOUSE 62 62 -
PKKRMRYFDPLR CIK2_XENLA 62 62 -
PEKRTQYFDPLR CIK4_BOVIN 213 213 -
PEKRTQYFDPLR CIK4_MOUSE 206 206 -
PEKRTQYFDPLR CIK4_MUSPF 206 206 -
PEKRTQYFDPLR CIK4_RAT 207 207 -
PAKRLRYFDPLR CIK5_MUSPF 138 138 -
PEKRTQYFDPLR CIK4_HUMAN 205 205 -
PAKRLRYFDPLR CIK5_RABIT 133 133 -
PVKRLRYFDPLR CIK5_MOUSE 140 140 -
PVKRLRYFDPLR Q9Z1R6 140 140 -
PAKRLPYFDPLR Q9TS07 134 134 -
PAKRLPYFDPLR CIK5_HUMAN 149 149 -
PAKRLHYFDPLR CIK5_RAT 140 140 -
PGRRVRFFDPLR Q61923 70 70 -
PKKRMRFFDPLR Q28293 62 62 -
PGRRVRFFDPLR CIK6_HUMAN 70 70 -
PGRRVRFFDPLR CIK6_RAT 70 70 -
PKKRMRYFDPLR Q9I830 61 61 -
PARRIRYFDPLR O61335 83 83 -
PARRLRYFDPLR CIK1_DROME 126 126 -
PARRLRYFDPLR CIK2_DROME 114 114 -
PARRLRYFDPLR CIK4_DROME 126 126 -
PRKRMRFFDPLR Q9I829 63 63 -
PQKRNRYYDPLR Q16968 95 95 -
REKRMQFFDSMR Q16322 115 115 -
PNKRNHYYDPLR Q26597 80 80 -
PKKRNRYYDPYR Q25376 69 69 -
RDKRMEFYDPLR Q9XXX0 95 95 -

Motif 2 width=11
Element Seqn Id St Int Rpt
YFFDRNRPSFD CIK1_HUMAN 80 2 -
YFFDRNRPSFD CIK1_RAT 80 2 -
YFFDRNRPSFD CIK1_MOUSE 80 2 -
YFFDRNRPSFD CIK3_HUMAN 95 2 -
YFFDRNRPSFD CIK3_MOUSE 100 2 -
YFFDRNRPSFD CIK3_RAT 97 2 -
YFFDRNRPSFD Q91781 77 2 -
YFFDRNRPSFD Q9PWM8 235 2 -
YFFDRNRPSFD Q9YGX8 235 2 -
YFFDRNRPSFD Q28656 88 2 -
YFFDRNRPSFD CIK2_HUMAN 76 2 -
YFFDRNRPSFD Q9MYX3 76 2 -
YFFDRNRPSFD CIK2_MOUSE 76 2 -
YFFDRNRPSFD CIK2_XENLA 76 2 -
YFFDRNRPSFD CIK4_BOVIN 227 2 -
YFFDRNRPSFD CIK4_MOUSE 220 2 -
YFFDRNRPSFD CIK4_MUSPF 220 2 -
YFFDRNRPSFD CIK4_RAT 221 2 -
YFFDRNRPSFD CIK5_MUSPF 152 2 -
YFFDRNRPSFD CIK4_HUMAN 219 2 -
YFFDRNRPSFD CIK5_RABIT 147 2 -
YFFDRNRPSFD CIK5_MOUSE 154 2 -
YFFDRNRPSFD Q9Z1R6 154 2 -
YFFDRNRPSFD Q9TS07 148 2 -
YFFDRNRPSFD CIK5_HUMAN 163 2 -
YFFDRNRPSFD CIK5_RAT 154 2 -
YFFDRNRPSFD Q61923 84 2 -
IFFVRNRPSFD Q28293 76 2 -
YFFDRNRPSFD CIK6_HUMAN 84 2 -
YFFDRNRPSFD CIK6_RAT 84 2 -
YFFDRSRTSFD Q9I830 75 2 -
YFFDRNRPSFD O61335 97 2 -
YFFDRSRPSFD CIK1_DROME 140 2 -
YFFDRSRPSFD CIK2_DROME 128 2 -
YFFDRSRPSFD CIK4_DROME 140 2 -
YFFDRNRPSFD Q9I829 77 2 -
YFFDRNRPSFD Q16968 109 2 -
YFFDRNRPSFD Q16322 129 2 -
YFFDRNRSSFD Q26597 94 2 -
YFFDGNRPSFD Q25376 83 2 -
YFFDRNRPSFD Q9XXX0 109 2 -

Motif 3 width=12
Element Seqn Id St Int Rpt
GEEAMEKFREDE CIK1_HUMAN 123 32 -
GEEAMEKFREDE CIK1_RAT 123 32 -
GEEAMEKFREDE CIK1_MOUSE 123 32 -
GEEAMEKFREDE CIK3_HUMAN 138 32 -
GEEAMEKFREDE CIK3_MOUSE 143 32 -
GEEAMEKFREDE CIK3_RAT 140 32 -
GEEAMEKFREDE Q91781 120 32 -
GEEAMLKFREDE Q9PWM8 278 32 -
GEEAMLKFREDE Q9YGX8 278 32 -
GEEAMEKFREDE Q28656 131 32 -
GEEAMEMFREDE CIK2_HUMAN 119 32 -
GEEAMEMFREDE Q9MYX3 119 32 -
GEEAMEMFREDE CIK2_MOUSE 119 32 -
GEEAMEIFREDE CIK2_XENLA 119 32 -
GEEALLKFREDE CIK4_BOVIN 270 32 -
GEEALLKFREDE CIK4_MOUSE 263 32 -
GEEALLKFREDE CIK4_MUSPF 263 32 -
GEEALLKFREDE CIK4_RAT 264 32 -
GDEAMERFREDE CIK5_MUSPF 195 32 -
GEEALLKFREDE CIK4_HUMAN 262 32 -
GDEAMERFREDE CIK5_RABIT 190 32 -
GDEAMERFREDE CIK5_MOUSE 197 32 -
GDEAMERFREDE Q9Z1R6 197 32 -
GEEAMERFREDE Q9TS07 191 32 -
GDEAMERFREDE CIK5_HUMAN 206 32 -
GDEAMERFREDE CIK5_RAT 197 32 -
GEEALAAFREDE Q61923 127 32 -
GEEAMEMFREDE Q28293 119 32 -
GDEALAAFREDE CIK6_HUMAN 127 32 -
GDEALAAFREDE CIK6_RAT 127 32 -
GDEAIELFREDE Q9I830 118 32 -
GEVAINKFREDE O61335 140 32 -
GDQAINKFREDE CIK1_DROME 183 32 -
GDQAINKFREDE CIK2_DROME 171 32 -
GDQAINKFREDE CIK4_DROME 183 32 -
EEEAIDMFKEDE Q9I829 120 32 -
GENAFERYREDE Q16968 152 32 -
GSEAMDQFREDE Q16322 172 32 -
GEEALAKYREEE Q26597 137 32 -
GEEVIDKYRAEE Q25376 126 32 -
GEMALEKYKADE Q9XXX0 152 32 -

Motif 4 width=17
Element Seqn Id St Int Rpt
FEYPESSGPARVIAIVS CIK1_HUMAN 157 22 -
FEYPESSGPARVIAIVS CIK1_RAT 157 22 -
FEYPESSGPARVIAIVS CIK1_MOUSE 157 22 -
FEYPESSGPARGIAIVS CIK3_HUMAN 172 22 -
FEYPESSGPARGIAIVS CIK3_MOUSE 177 22 -
FEYPESSGPARGIAIVS CIK3_RAT 174 22 -
FEFPESSGPARIIAIIS Q91781 154 22 -
FEYPESSSPARGIAIVS Q9PWM8 313 23 -
FEYPESSSPARGIAIVS Q9YGX8 313 23 -
FEYPESSGPARGIAIVS Q28656 165 22 -
FEYPESSGPARIIAIVS CIK2_HUMAN 153 22 -
FEYPESSGPARIIAIVS Q9MYX3 153 22 -
FEYPESSGPARIIAIVS CIK2_MOUSE 153 22 -
FEYPESSGPARIIAIIS CIK2_XENLA 153 22 -
FEYPESSSPARGIAIVS CIK4_BOVIN 305 23 -
FEYPESSSPARGIAIVS CIK4_MOUSE 298 23 -
FEYPESSSPARGIAIVS CIK4_MUSPF 298 23 -
FEYPESSSPARGIAIVS CIK4_RAT 299 23 -
FEYPESSGSARGIAIVS CIK5_MUSPF 229 22 -
FEYPESSDPARGIAIVS CIK4_HUMAN 297 23 -
FEYPESSGSARAIAIVS CIK5_RABIT 224 22 -
FEYPESSGSARAIAIVS CIK5_MOUSE 231 22 -
FEYPESSGSARAIAIVS Q9Z1R6 231 22 -
FEYPESSGSARAIAIVS Q9TS07 225 22 -
FEYPESSGSARAIAIVS CIK5_HUMAN 240 22 -
FEYPESSGSARAIAIVS CIK5_RAT 231 22 -
FEYPESSGPARGIAIVS Q61923 164 25 -
FEYPESSGPARIIAIVS Q28293 153 22 -
FEYPESSGPARGIAIVS CIK6_HUMAN 164 25 -
FEYPESSGPARGIAIVS CIK6_RAT 164 25 -
FEYPESSGPARIIAIIS Q9I830 152 22 -
FEYPESSQNARVVAIIS O61335 174 22 -
FEYPESSQAARVVAIIS CIK1_DROME 217 22 -
FEYPESSQAARVVAIIS CIK2_DROME 205 22 -
FEYPESSQAARVVAIIS CIK4_DROME 217 22 -
FEYPESSGPARMIAVVS Q9I829 154 22 -
FEYPESSAAARLCAIFS Q16968 186 22 -
FEYPESSSAARAVAVVS Q16322 206 22 -
FEYPESSLAARILAIGS Q26597 171 22 -
VEHPESSTPARVIAIVS Q25376 160 22 -
FEYPESSAAARGIAIMS Q9XXX0 186 22 -

Motif 5 width=12
Element Seqn Id St Int Rpt
SIVIFCLETLPE CIK1_HUMAN 180 6 -
SIVIFCLETLPE CIK1_RAT 180 6 -
SIVIFCLETLPE CIK1_MOUSE 180 6 -
SIVIFCLETLPE CIK3_HUMAN 195 6 -
SIVIFCLETLPE CIK3_MOUSE 200 6 -
SIVIFCLETLPE CIK3_RAT 197 6 -
SIVIFCLETLPE Q91781 177 6 -
SIVIFCLETLPE Q9PWM8 336 6 -
SIVIFCLETLPE Q9YGX8 336 6 -
SIVIFCLETLPE Q28656 188 6 -
SIVSFCLETLPI CIK2_HUMAN 176 6 -
SIVSFCLETLPI Q9MYX3 176 6 -
SIVSFCLETLPI CIK2_MOUSE 176 6 -
SIVSFCLETLPV CIK2_XENLA 176 6 -
SIVIFCLETLPE CIK4_BOVIN 328 6 -
SIVIFCLETLPE CIK4_MOUSE 321 6 -
SIVIFCLETLPE CIK4_MUSPF 321 6 -
SIVIFCLETLPE CIK4_RAT 322 6 -
SIITFCLETLPE CIK5_MUSPF 252 6 -
SIVIFCLETLPE CIK4_HUMAN 320 6 -
SIITFCLETLPE CIK5_RABIT 247 6 -
SIITFCLETLPE CIK5_MOUSE 254 6 -
SIITFCLETLPE Q9Z1R6 254 6 -
SIITFCLETLPE Q9TS07 248 6 -
SIITFCLETLPE CIK5_HUMAN 263 6 -
SIITFCLETLPE CIK5_RAT 254 6 -
SIVIFCLETLPQ Q61923 187 6 -
SIVSFCLETLPI Q28293 176 6 -
SIVIFCLETLPQ CIK6_HUMAN 187 6 -
SIVIFCLETLPQ CIK6_RAT 187 6 -
SIVSFCLETLPI Q9I830 175 6 -
SIVIFCLETLPE O61335 197 6 -
SIVIFCLETLPE CIK1_DROME 240 6 -
SIVIFCLETLPE CIK2_DROME 228 6 -
SIVIFCLETLPE CIK4_DROME 240 6 -
SIVIFCLETLPQ Q9I829 177 6 -
SIVIFCLETLPQ Q16968 209 6 -
SITIFCLETLPE Q16322 229 6 -
SIIIFCLETLPH Q26597 194 6 -
SIVTFCLETLPE Q25376 183 6 -
SIISFCLETLPA Q9XXX0 209 6 -