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PR01483

Identifier
FASYNTHASE  [View Relations]  [View Alignment]  
Accession
PR01483
No. of Motifs
12
Creation Date
06-NOV-2000
Title
Fatty acid synthase signature
Database References
Literature References
1. CHIRALA, S.S., KUZIORA, M.A., SPECTOR, D.M. AND WAKIL, S.J.
Complementation of mutations and nucleotide sequence of FAS1 gene encoding
beta subunit of yeast fatty acid synthase.
J.BIOL.CHEM. 262 4231-4240 (1987). 
 
2. KOTTIG, H., ROTTNER, G., BECK, K.F., SCHWEIZER, M. AND SCHWEIZER, E.
The pentafunctional FAS1 genes of Saccharomyces cerevisiae and Yarrowia
lipolytica are co-linear and considerably longer than previously estimated
MOL.GEN.GENET. 226 310-314(1991). 
 
3. BROWN, D.W., YU, J.H., KELKAR, H.S., FERNANDES, M., NESBITT, T.C.,
KELLER N.P., ADAMS, T.H. AND LEONARD, T.J.
Twenty-five coregulated transcripts define a sterigmatocystin gene cluster
in Aspergillus nidulans.
PROC.NATL.ACAD.SCI.U.S.A. 93 1418-1422 (1996).

Documentation
The yeast fatty acid synthase (FAS) is a hexameric complex (alpha 6 beta 6)
of two multifunctional proteins, alpha and beta [1]. The alpha subunit
contains two of the seven enzymatic activities required for the synthesis
of fatty acids, together with the site for attachment of the prosthetic
group 4'-phosphopantetheine [1]. The beta subunit contains the remaining
five enzyme domains: acetyltransferase and malonyltransferase, s-acyl fatty
acid synthase thioesterase, enoyl-[acyl-carrier protein] reductase, and
3-hydroxypalmitoyl-[acyl-carrier protein] dehydratase.
 
The sequential order of the five FAS1-encoded enzyme domains is co-linear 
in Yarrowia lipolytica and Saccharomyces cerevisiae, which observation is
consistent with evidence that the functional organisation of FAS genes is
similar in related organisms but differs between unrelated species [2].
 
Sterigmatocystin (ST) and the aflatoxins (AFs) (related fungal secondary 
metabolites) are among the most toxic, mutagenic and carcinogenic natural
products known [3]. In Aspergillus nidulans, the ST biosynthetic pathway is 
believed to involve at least 15 enzymatic activities; some Aspergillus
parasiticus, Aspergillus flavus and Aspergillus nomius strains contain
additional activities that convert ST to AF [3]. 
 
A 60kb region of the A.nidulans genome has been characterised and found to
contain virtually all of the genes needed for ST biosynthesis [3]. The
deduced polypeptide sequences of regions within this cluster share a high
degree of similarity with enzymes that have activities predicted for ST/AF
biosynthesis, including a polyketide synthase, a fatty acid synthase
(alpha and beta subunits), five monooxygenases, four dehydrogenases, an
esterase, an 0-methyltransferase, a reductase, an oxidase and a zinc
cluster DNA binding protein [3].
 
FASYNTHASE is a 12-element fingerprint that provides a signature for the 
fatty acid synthases. The fingerprint was derived from an initial alignment
of 4 sequences: the motifs were drawn from conserved regions largely 
spanning the central portion of the alignment - motifs 1-4 reside in the
enoyl reductase domain; motifs 5 and 6 lie between the enoyl reductase and
dehyrdatase domains; motifs 7 and 8 reside within the dehyrdatase domain;
and motifs 9-12 reside in the malonyl/palmitoyl transferase domain. Three
iterations on SPTR39_14f were required to reach convergence, at which point
a true set comprising 13 sequences was identified. Several partial matches
were also found: Q48926 is a fatty acid synthase from Mycobacterium bovis
that matches motifs 1, 2, 6, 7, 9 and 11; O59897 and O60026 are polyketide
synthases from Aspergillus fumigatus that match motifs 9 and 11; and O53664
and O69502 are hypothetical 30kDa proteins from Mycobacterium tuberculosis
and Mycobacterium leprae, both of which match motifs 6 and 7.
Summary Information
  13 codes involving 12 elements
0 codes involving 11 elements
0 codes involving 10 elements
0 codes involving 9 elements
0 codes involving 8 elements
1 codes involving 7 elements
0 codes involving 6 elements
0 codes involving 5 elements
0 codes involving 4 elements
0 codes involving 3 elements
4 codes involving 2 elements
Composite Feature Index
12131313131313131313131313
11000000000000
10000000000000
9000000000000
8000000000000
7110001101011
6000000000000
5000000000000
4000000000000
3000000000000
2000000222020
123456789101112
True Positives
FAS1_CANAL    FAS1_YARLI    FAS1_YEAST    P78616        
P78799 P95029 Q04846 Q05747
Q59497 Q92215 Q9UUG0 Q9X7E2
STCK_EMENI
True Positive Partials
Codes involving 7 elements
Q48926
Codes involving 2 elements
O53664 O59897 O60026 O69502
Sequence Titles
FAS1_CANAL  FATTY ACID SYNTHASE, SUBUNIT BETA (EC 2.3.1.86) [INCLUDES: 3- HYDROXYPALMITOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE (EC 4.2.1.61); ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH] (EC 1.3.1.9); [ACYL- CARRIER-PROTEIN] ACETYLTRANSFERASE (EC 2.3.1.38); [ACYL-CARRIER- PROTEIN] MALONYLTRANSFERASE (EC 2.3.1.39); S-ACYL FATTY ACID SYNTHASE THIOESTERASE (EC 3.1.2.14)] - Candida albicans (Yeast). 
FAS1_YARLI FATTY ACID SYNTHASE, SUBUNIT BETA (EC 2.3.1.86) [INCLUDES: 3- HYDROXYPALMITOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE (EC 4.2.1.61); ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH] (EC 1.3.1.9); [ACYL- CARRIER-PROTEIN] ACETYLTRANSFERASE (EC 2.3.1.38); [ACYL-CARRIER- PROTEIN] MALONYLTRANSFERASE (EC 2.3.1.39); S-ACYL FATTY ACID SYNTHASE THIOESTERASE (EC 3.1.2.14)] - Yarrowia lipolytica (Candida lipolytica).
FAS1_YEAST FATTY ACID SYNTHASE, SUBUNIT BETA (EC 2.3.1.86) [INCLUDES: 3- HYDROXYPALMITOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE (EC 4.2.1.61); ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH] (EC 1.3.1.9); [ACYL- CARRIER-PROTEIN] ACETYLTRANSFERASE (EC 2.3.1.38); [ACYL-CARRIER- PROTEIN] MALONYLTRANSFERASE (EC 2.3.1.39); S-ACYL FATTY ACID SYNTHASE THIOESTERASE (EC 3.1.2.14)] - Saccharomyces cerevisiae (Baker's yeast).
P78616 FATTY ACID SYNTHASE, BETA SUBUNIT - Emericella nidulans (Aspergillus nidulans).
P78799 FATTY ACID SYNTHETASE - Schizosaccharomyces pombe (Fission yeast).
P95029 RV2524C - Mycobacterium tuberculosis.
Q04846 FATTY ACID SYNTHASE (EC 2.3.1.85) (CONTAINS: EC 2.3.1.38, EC 2.3.1.39, EC 2.3.1.41, EC 1.1.1.100, EC 4.2.1.60, EC 4.2.1.61, EC 1.3.1.10, AND EC 3.1.2.14) - Corynebacterium ammoniagenes (Brevibacterium ammoniagenes).
Q05747 FATTY ACID SYNTHASE BETA SUBUNIT - Saccharomyces cerevisiae (Baker's yeast).
Q59497 FATTY-ACID SYNTHASE (EC 2.3.1.85) - Corynebacterium ammoniagenes (Brevibacterium ammoniagenes).
Q92215 PUTATIVE FATTY ACID SYNTHASE BETA - Cochliobolus carbonum (Bipolaris zeicola).
Q9UUG0 FATTY ACID SYNTHASE, SUBUNIT BETA - Schizosaccharomyces pombe (Fission yeast).
Q9X7E2 PUTATIVE TYPE I FATTY ACID SYNTHASE - Mycobacterium leprae.
STCK_EMENI PUTATIVE STERIGMATOCYSTIN BIOSYNTHESIS FATTY ACID SYNTHASE BETA SUBUNIT - Emericella nidulans (Aspergillus nidulans).

Q48926 FATTY ACID SYNTHASE - Mycobacterium bovis.

O53664 HYPOTHETICAL 30.2 KDA PROTEIN - Mycobacterium tuberculosis.
O59897 POLYKETIDE SYNTHASE - Aspergillus fumigatus (Sartorya fumigata).
O60026 POLYKETIDE SYNTHASE - Aspergillus fumigatus (Sartorya fumigata).
O69502 HYPOTHETICAL 30.5 KDA PROTEIN - Mycobacterium leprae.
Scan History
SPTR39_14f 3  25   NSINGLE    
Initial Motifs
Motif 1  width=21
Element Seqn Id St Int Rpt
TKFSQLLGRAPLMVAGMTPTT FAS1_CANAL 568 568 -
TKFSKLIGRPPLLVPGMTPCT FAS1_YEAST 581 581 -
TKFSRLTGRAPIMVAGMTPTT FAS1_YARLI 582 582 -
TKMTRLLGTPHVMVAGMTPTT STCK_EMENI 443 443 -

Motif 2 width=19
Element Seqn Id St Int Rpt
VSASLNAGYHIELAGGGYF FAS1_CANAL 594 5 -
VAATTNAGYTIELAGGGYF FAS1_YEAST 607 5 -
VAATMNSGYHIELGGGGYF FAS1_YARLI 608 5 -
VAAIIQADYHVEFACGGYY STCK_EMENI 469 5 -

Motif 3 width=19
Element Seqn Id St Int Rpt
KPGSVDAISQVIAIAKAHP FAS1_CANAL 693 80 -
KPGSIDAISQVINIAKAHP FAS1_YEAST 706 80 -
KPGSIEAISSVIRIAKANP FAS1_YARLI 707 80 -
KPGSVDAIDRVLTIARQYP STCK_EMENI 569 81 -

Motif 4 width=20
Element Seqn Id St Int Rpt
FPIVLQWTGGRGGGHHSFED FAS1_CANAL 713 1 -
FPIALQWTGGRGGGHHSFED FAS1_YEAST 726 1 -
FPIILQWTGGRGGGHHSFED FAS1_YARLI 727 1 -
LPVGIQWTGGRAGGHHSCED STCK_EMENI 589 1 -

Motif 5 width=19
Element Seqn Id St Int Rpt
DLQEMTYKEVANRLVELMY FAS1_CANAL 900 167 -
DLATMTYEEVAKRLVELMF FAS1_YEAST 913 167 -
DLEDLTYAEVIQRLVDLMY FAS1_YARLI 915 168 -
EIEELSYRQVLRRLCQLTY STCK_EMENI 783 174 -

Motif 6 width=25
Element Seqn Id St Int Rpt
QKPVPFVPVLDERFEFFFKKDSLWQ FAS1_CANAL 1000 81 -
QKPVPFVPVLDRRFEIFFKKDSLWQ FAS1_YEAST 1012 80 -
QKPVPFIPVLDDNFEFFFKKDSLWQ FAS1_YARLI 1016 82 -
QKPVPFIPRLDADFQTWFKKDSLWQ STCK_EMENI 880 78 -

Motif 7 width=23
Element Seqn Id St Int Rpt
PGTNEPYAIVSGDYNPIHVSRVF FAS1_CANAL 1533 508 -
PSTNEPYARVSGDLNPIHVSRHF FAS1_YEAST 1547 510 -
PSSNEPYAGVSGDYNPIHVSRAF FAS1_YARLI 1568 527 -
PAQSEGYAMVSGDTNPIHVCPLF STCK_EMENI 1430 525 -

Motif 8 width=22
Element Seqn Id St Int Rpt
FAAYAKLPGTITHGMYSSASIR FAS1_CANAL 1555 -1 -
FASYANLPGTITHGMFSSASVR FAS1_YEAST 1569 -1 -
FASYASLPGTITQGMYSSAAVR FAS1_YARLI 1590 -1 -
FSRFAGLGQPVVHGLHLSATVR STCK_EMENI 1452 -1 -

Motif 9 width=20
Element Seqn Id St Int Rpt
EAEIEQPTTTYVFTGQGSQE FAS1_CANAL 1641 64 -
EAEIEQPVTTFVFTGQGSQE FAS1_YEAST 1654 63 -
EAEVEQPISTFVFTGQGSQE FAS1_YARLI 1676 64 -
EAVLEQAQTTYVFTGQGTQE STCK_EMENI 1538 64 -

Motif 10 width=24
Element Seqn Id St Int Rpt
GMGMELYNSSEVAREVWDKADRHF FAS1_CANAL 1662 1 -
GMGMDLYKTSKAAQDVWNRADNHF FAS1_YEAST 1675 1 -
GMGMDLYASSEVAKKVWDKADEHF FAS1_YARLI 1697 1 -
GMGMALYDTNAAARAVWDRAERHF STCK_EMENI 1559 1 -

Motif 11 width=20
Element Seqn Id St Int Rpt
GLIPSDIMFAGHSLGEYSAL FAS1_CANAL 1784 98 -
GLIPADATFAGHSLGEYAAL FAS1_YEAST 1796 97 -
GLVPVDATFAGHSLGEYSAL FAS1_YARLI 1820 99 -
GVVQTQAIFAGHSLGEYSSL STCK_EMENI 1672 89 -

Motif 12 width=22
Element Seqn Id St Int Rpt
FYRGMTMQVAVPRDELGRSNYG FAS1_CANAL 1820 16 -
FYRGMTMQVAVPRDELGRSNYG FAS1_YEAST 1832 16 -
FYRGMTMQVAVPRDAQGRSNYG FAS1_YARLI 1856 16 -
LYRGLKMQNTLPRNANGRTDYG STCK_EMENI 1708 16 -
Final Motifs
Motif 1  width=21
Element Seqn Id St Int Rpt
TKFSQLLGRAPLMVAGMTPTT FAS1_CANAL 568 568 -
TKFSKLIGRPPLLVPGMTPCT FAS1_YEAST 581 581 -
TKMSRLLGIPPIMVAGMTPTT P78616 592 592 -
TKFSRLTGRAPIMVAGMTPTT FAS1_YARLI 582 582 -
TKFSKLIGRPPLLVPGMTPCT Q05747 581 581 -
TRLSRMLGLPPLWVAGMTPTS P78799 571 571 -
TRLSRMLGLPPLWVAGMTPTS Q9UUG0 571 571 -
TKMSRLLGLPPIMVGGMTPTT Q92215 582 582 -
TKFTRLTGRSPILLAGMTPTT P95029 409 409 -
TKFTRLTGRSPILLAGMTPTT Q9X7E2 409 409 -
TKMTRLLGTPHVMVAGMTPTT STCK_EMENI 443 443 -
TRFTELTGYSPVVLAGMTPST Q04846 378 378 -
TRFSEWTGMSPIILGGMTPTT Q59497 365 365 -

Motif 2 width=19
Element Seqn Id St Int Rpt
VSASLNAGYHIELAGGGYF FAS1_CANAL 594 5 -
VAATTNAGYTIELAGGGYF FAS1_YEAST 607 5 -
VAATMNAGYHIELAGGGYY P78616 618 5 -
VAATMNSGYHIELGGGGYF FAS1_YARLI 608 5 -
VAATTNAGYTIELAGGGYF Q05747 607 5 -
CSAIAKAGFTYELAGGGYF P78799 597 5 -
CSAIAKAGFTYELAGGGYF Q9UUG0 597 5 -
VAATMNAGYHIELAAGGYS Q92215 608 5 -
VAAAANAGHWAELAGGGQV P95029 435 5 -
VAAAANAGHWAELAGGGQV Q9X7E2 435 5 -
VAAIIQADYHVEFACGGYY STCK_EMENI 469 5 -
VAAAANAGFWAELAGGGQV Q04846 404 5 -
VAAAANGGYWSEMAGGGQY Q59497 391 5 -

Motif 3 width=19
Element Seqn Id St Int Rpt
KPGSVDAISQVIAIAKAHP FAS1_CANAL 693 80 -
KPGSIDAISQVINIAKAHP FAS1_YEAST 706 80 -
KPGSVDAIQQVINIAKANP P78616 717 80 -
KPGSIEAISSVIRIAKANP FAS1_YARLI 707 80 -
KPGSIDAISQVINIAKAHP Q05747 706 80 -
KPGSVEAVNAVISIAKANP P78799 696 80 -
KPGSVEAVNAVISIAKANP Q9UUG0 696 80 -
KPGPTTAIDAVIEIAQANP Q92215 707 80 -
KPGTIEQIRSVIRIATEVP P95029 540 86 -
KPGTIEQIRSVIRIATEMS Q9X7E2 540 86 -
KPGSVDAIDRVLTIARQYP STCK_EMENI 569 81 -
KPGAVRHVHQVLAIADDLP Q04846 509 86 -
KPGTTKQIQDCVAIAADNP Q59497 496 86 -

Motif 4 width=20
Element Seqn Id St Int Rpt
FPIVLQWTGGRGGGHHSFED FAS1_CANAL 713 1 -
FPIALQWTGGRGGGHHSFED FAS1_YEAST 726 1 -
FPVILQWTGGRGGGHHSFED P78616 737 1 -
FPIILQWTGGRGGGHHSFED FAS1_YARLI 727 1 -
FPIALQWTGGRGGGHHSFED Q05747 726 1 -
FPIVLQWTGGRAGGHHSFED P78799 716 1 -
FPIVLQWTGGRAGGHHSFED Q9UUG0 716 1 -
FPVFLQWTGGRSGGHHSNED Q92215 727 1 -
KPVIMHVEGGRAGGHHSWED P95029 560 1 -
KPVIMHVEGGRAGGHHSWED Q9X7E2 560 1 -
LPVGIQWTGGRAGGHHSCED STCK_EMENI 589 1 -
TTVIMQVEGGKAGGHHSWED Q04846 529 1 -
HRVIIQIEDAHAGGHHSWVD Q59497 516 1 -

Motif 5 width=19
Element Seqn Id St Int Rpt
DLQEMTYKEVANRLVELMY FAS1_CANAL 900 167 -
DLATMTYEEVAKRLVELMF FAS1_YEAST 913 167 -
DLEDMTYAEVVHRMVDLMY P78616 925 168 -
DLEDLTYAEVIQRLVDLMY FAS1_YARLI 915 168 -
DLATMTYEEVAKRLVELMF Q05747 913 167 -
SVEDMTYAELLYRAIDLMY P78799 914 178 -
SVEDMTYAELLYRAIDLMY Q9UUG0 914 178 -
ELRDMTYAEVLRRMVQLLY Q92215 915 168 -
DVADMTYLQWLRRYVELAI P95029 730 150 -
DVSEMTYLQWLQRYVELTI Q9X7E2 730 150 -
EIEELSYRQVLRRLCQLTY STCK_EMENI 783 174 -
DINAMTYAEWLARYVEVSY Q04846 704 155 -
DLSEMTYEDWVARFAERAY Q59497 689 153 -

Motif 6 width=25
Element Seqn Id St Int Rpt
QKPVPFVPVLDERFEFFFKKDSLWQ FAS1_CANAL 1000 81 -
QKPVPFVPVLDRRFEIFFKKDSLWQ FAS1_YEAST 1012 80 -
QKPVPFVPSLDENFEYWFKKDSLWQ P78616 1025 81 -
QKPVPFIPVLDDNFEFFFKKDSLWQ FAS1_YARLI 1016 82 -
QKPVPFVPVLDRRFEIFFKKDSLWQ Q05747 1012 80 -
QKPVPFIPAIDDTFEFYFKKDSLWQ P78799 1014 81 -
QKPVPFIPAIDDTFEFYFKKDSLWQ Q9UUG0 1014 81 -
QKPVPFVPALDEDFEFFFKKDSLWQ Q92215 1015 81 -
GKPVNFVPVIDQDVRRWWRSDSLWQ P95029 840 91 -
GKPVNFVPVIDKDVRRWWRSDSLWQ Q9X7E2 840 91 -
QKPVPFIPRLDADFQTWFKKDSLWQ STCK_EMENI 880 78 -
GKPPAFVPVIDSDVRRWWRQDSLWQ Q04846 800 77 -
VKPMPWTTAIDGDLKEWFAKDTLWQ Q59497 785 77 -

Motif 7 width=23
Element Seqn Id St Int Rpt
PGTNEPYAIVSGDYNPIHVSRVF FAS1_CANAL 1533 508 -
PSTNEPYARVSGDLNPIHVSRHF FAS1_YEAST 1547 510 -
PASNETYARVSGDYNPIHVSRVF P78616 1572 522 -
PSSNEPYAGVSGDYNPIHVSRAF FAS1_YARLI 1568 527 -
PSTNEPYARVSGDLNPIHVSRHF Q05747 1547 510 -
PPTNSPYAEVSGDYNPIHVSPTF P78799 1563 524 -
PPTNSPYAEVSGDYNPIHVSPTF Q9UUG0 1563 524 -
PSSNEAYARTSGDLNPIHVSRTF Q92215 1565 525 -
PVDMRPFAVVSGDHNPIHTDRAA P95029 1217 352 -
PIDMRPFAVVSGDHNPIHTDRTA Q9X7E2 1219 354 -
PAQSEGYAMVSGDTNPIHVCPLF STCK_EMENI 1430 525 -
PASMHPFAVVTGDRNPIHVSAAA Q04846 1163 338 -
PSDMTPFALVSGDYNPIHTSTNA Q59497 1185 375 -

Motif 8 width=22
Element Seqn Id St Int Rpt
FAAYAKLPGTITHGMYSSASIR FAS1_CANAL 1555 -1 -
FASYANLPGTITHGMFSSASVR FAS1_YEAST 1569 -1 -
FSSYANLPGTITHGMYTSAAVR P78616 1594 -1 -
FASYASLPGTITQGMYSSAAVR FAS1_YARLI 1590 -1 -
FASYANLLGTITHGMFSSTSVR Q05747 1569 -1 -
AFVELPGTHGITHGMYTSAAAR P78799 1587 1 -
AFVELPGTHGITHGMYTSAAAR Q9UUG0 1587 1 -
FAEYAGLPGLITHGMYCSAAIQ Q92215 1587 -1 -
AALLAGLESPIVHGMWLSAAAQ P95029 1239 -1 -
AALLAGLESPIVHGMWLSAAAQ Q9X7E2 1241 -1 -
FSRFAGLGQPVVHGLHLSATVR STCK_EMENI 1452 -1 -
ARLAGLENGVIVHGMWTSAIGQ Q04846 1186 0 -
AARLVNLDAPLVHGMWLSATAQ Q59497 1207 -1 -

Motif 9 width=20
Element Seqn Id St Int Rpt
EAEIEQPTTTYVFTGQGSQE FAS1_CANAL 1641 64 -
EAEIEQPVTTFVFTGQGSQE FAS1_YEAST 1654 63 -
EAEVEQPVTAYVFTGQGSQE P78616 1680 64 -
EAEVEQPISTFVFTGQGSQE FAS1_YARLI 1676 64 -
EAEIEQPVTTFVFTGQGSQE Q05747 1654 63 -
TAEVEQPVSAYVFTGQGSQE P78799 1673 64 -
TAEVEQPVSAYVFTGQGSQE Q9UUG0 1673 64 -
EAKITQKMTTYVFTGQGSQE Q92215 1673 64 -
SARLAAPKTVYAFPGQGIQH P95029 1324 63 -
TARLAAPKTVYAFPGQGIQH Q9X7E2 1326 63 -
EAVLEQAQTTYVFTGQGTQE STCK_EMENI 1538 64 -
TATMAAPRTFYGFPGQGIQS Q04846 1268 60 -
QALMAQPRTAYVYPGQGIQA Q59497 1285 56 -

Motif 10 width=24
Element Seqn Id St Int Rpt
GMGMELYNSSEVAREVWDKADRHF FAS1_CANAL 1662 1 -
GMGMDLYKTSKAAQDVWNRADNHF FAS1_YEAST 1675 1 -
GMGMELYATSPVAKEVWDRPSFHW P78616 1701 1 -
GMGMDLYASSEVAKKVWDKADEHF FAS1_YARLI 1697 1 -
GMGMDLYKTSKAAQDVWNRADNHF Q05747 1675 1 -
GMGMDLYASSPVARKIWDSADKHF P78799 1694 1 -
GMGMDLYASSPVARKIWDSADKHF Q9UUG0 1694 1 -
GMGMDLYNQCPAAREVWDRGDKYF Q92215 1694 1 -
GMGMEVRARSKAARKVWDTADKFT P95029 1345 1 -
GMGMDVRARSKAARRVWDDADKFT Q9X7E2 1347 1 -
GMGMALYDTNAAARAVWDRAERHF STCK_EMENI 1559 1 -
GMGMESYASSSAAREVWERADAHT Q04846 1289 1 -
GMGRGDRDASAAAREVWRRADRHT Q59497 1306 1 -

Motif 11 width=20
Element Seqn Id St Int Rpt
GLIPSDIMFAGHSLGEYSAL FAS1_CANAL 1784 98 -
GLIPADATFAGHSLGEYAAL FAS1_YEAST 1796 97 -
GLVQRDSSFAGHSLGEYSAL P78616 1821 96 -
GLVPVDATFAGHSLGEYSAL FAS1_YARLI 1820 99 -
GLIPADATFAGHSLGEYAAL Q05747 1796 97 -
GLVQNDCAFAGHSLGEYSAL P78799 1816 98 -
GLVQNDCAFAGHSLGEYSAL Q9UUG0 1816 98 -
GLVDGNCYYAGHSLGEFSAL Q92215 1816 98 -
GAFVEGAIACGHSVGEYTAL P95029 1426 57 -
GAFVEGAIACGHSVGEYTAL Q9X7E2 1428 57 -
GVVQTQAIFAGHSLGEYSSL STCK_EMENI 1672 89 -
GVKSQDTYFAGHSVGEYNAL Q04846 1370 57 -
DALGTNSMYAGHSLGEYTAL Q59497 1387 57 -

Motif 12 width=22
Element Seqn Id St Int Rpt
FYRGMTMQVAVPRDELGRSNYG FAS1_CANAL 1820 16 -
FYRGMTMQVAVPRDELGRSNYG FAS1_YEAST 1832 16 -
FYRGLTMQVAVERDEQGRSNYS P78616 1857 16 -
FYRGMTMQVAVPRDAQGRSNYG FAS1_YARLI 1856 16 -
FYRGMTMQVAVPRDELGRSNYG Q05747 1832 16 -
FLRGLTMQNAVHRDELGRSDYG P78799 1852 16 -
FLRGLTMQNAVHRDELGRSDYG Q9UUG0 1852 16 -
FYRGLTMQKAVNRDESGRSNYS Q92215 1852 16 -
FHRGSKMHDIVPRDELGRSNYR P95029 1462 16 -
FHRGSKMHDIVLRDELGRSNYR Q9X7E2 1464 16 -
LYRGLKMQNTLPRNANGRTDYG STCK_EMENI 1708 16 -
YARGLTMHRLVDRDAEGNSNYG Q04846 1406 16 -
YSRGSAMGTLVERDENGNSNYG Q59497 1423 16 -