| Identifier | FASYNTHASE [View Relations] [View Alignment]
|
| Accession | PR01483 |
| No. of Motifs | 12 |
| Creation Date | 06-NOV-2000 |
| Title | Fatty acid synthase signature |
| Database References | |
| Literature References | 1. CHIRALA, S.S., KUZIORA, M.A., SPECTOR, D.M. AND WAKIL, S.J.
Complementation of mutations and nucleotide sequence of FAS1 gene encoding
beta subunit of yeast fatty acid synthase.
J.BIOL.CHEM. 262 4231-4240 (1987).
2. KOTTIG, H., ROTTNER, G., BECK, K.F., SCHWEIZER, M. AND SCHWEIZER, E.
The pentafunctional FAS1 genes of Saccharomyces cerevisiae and Yarrowia
lipolytica are co-linear and considerably longer than previously estimated
MOL.GEN.GENET. 226 310-314(1991).
3. BROWN, D.W., YU, J.H., KELKAR, H.S., FERNANDES, M., NESBITT, T.C.,
KELLER N.P., ADAMS, T.H. AND LEONARD, T.J.
Twenty-five coregulated transcripts define a sterigmatocystin gene cluster
in Aspergillus nidulans.
PROC.NATL.ACAD.SCI.U.S.A. 93 1418-1422 (1996).
|
| Documentation | The yeast fatty acid synthase (FAS) is a hexameric complex (alpha 6 beta 6)
of two multifunctional proteins, alpha and beta [1]. The alpha subunit
contains two of the seven enzymatic activities required for the synthesis
of fatty acids, together with the site for attachment of the prosthetic
group 4'-phosphopantetheine [1]. The beta subunit contains the remaining
five enzyme domains: acetyltransferase and malonyltransferase, s-acyl fatty
acid synthase thioesterase, enoyl-[acyl-carrier protein] reductase, and
3-hydroxypalmitoyl-[acyl-carrier protein] dehydratase.
The sequential order of the five FAS1-encoded enzyme domains is co-linear
in Yarrowia lipolytica and Saccharomyces cerevisiae, which observation is
consistent with evidence that the functional organisation of FAS genes is
similar in related organisms but differs between unrelated species [2].
Sterigmatocystin (ST) and the aflatoxins (AFs) (related fungal secondary
metabolites) are among the most toxic, mutagenic and carcinogenic natural
products known [3]. In Aspergillus nidulans, the ST biosynthetic pathway is
believed to involve at least 15 enzymatic activities; some Aspergillus
parasiticus, Aspergillus flavus and Aspergillus nomius strains contain
additional activities that convert ST to AF [3].
A 60kb region of the A.nidulans genome has been characterised and found to
contain virtually all of the genes needed for ST biosynthesis [3]. The
deduced polypeptide sequences of regions within this cluster share a high
degree of similarity with enzymes that have activities predicted for ST/AF
biosynthesis, including a polyketide synthase, a fatty acid synthase
(alpha and beta subunits), five monooxygenases, four dehydrogenases, an
esterase, an 0-methyltransferase, a reductase, an oxidase and a zinc
cluster DNA binding protein [3].
FASYNTHASE is a 12-element fingerprint that provides a signature for the
fatty acid synthases. The fingerprint was derived from an initial alignment
of 4 sequences: the motifs were drawn from conserved regions largely
spanning the central portion of the alignment - motifs 1-4 reside in the
enoyl reductase domain; motifs 5 and 6 lie between the enoyl reductase and
dehyrdatase domains; motifs 7 and 8 reside within the dehyrdatase domain;
and motifs 9-12 reside in the malonyl/palmitoyl transferase domain. Three
iterations on SPTR39_14f were required to reach convergence, at which point
a true set comprising 13 sequences was identified. Several partial matches
were also found: Q48926 is a fatty acid synthase from Mycobacterium bovis
that matches motifs 1, 2, 6, 7, 9 and 11; O59897 and O60026 are polyketide
synthases from Aspergillus fumigatus that match motifs 9 and 11; and O53664
and O69502 are hypothetical 30kDa proteins from Mycobacterium tuberculosis
and Mycobacterium leprae, both of which match motifs 6 and 7.
|
| Summary Information | 13 codes involving 12 elements
0 codes involving 11 elements
0 codes involving 10 elements
0 codes involving 9 elements
0 codes involving 8 elements
1 codes involving 7 elements
0 codes involving 6 elements
0 codes involving 5 elements
0 codes involving 4 elements
0 codes involving 3 elements
4 codes involving 2 elements
|
| Composite Feature Index | | 12 | 13 | 13 | 13 | 13 | 13 | 13 | 13 | 13 | 13 | 13 | 13 | 13 | | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | | 7 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 2 | 0 | 2 | 0 | | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 |
|
| True Positives | FAS1_CANAL FAS1_YARLI FAS1_YEAST P78616
P78799 P95029 Q04846 Q05747
Q59497 Q92215 Q9UUG0 Q9X7E2
STCK_EMENI |
| True Positive Partials | |
| Sequence Titles | FAS1_CANAL FATTY ACID SYNTHASE, SUBUNIT BETA (EC 2.3.1.86) [INCLUDES: 3- HYDROXYPALMITOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE (EC 4.2.1.61); ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH] (EC 1.3.1.9); [ACYL- CARRIER-PROTEIN] ACETYLTRANSFERASE (EC 2.3.1.38); [ACYL-CARRIER- PROTEIN] MALONYLTRANSFERASE (EC 2.3.1.39); S-ACYL FATTY ACID SYNTHASE THIOESTERASE (EC 3.1.2.14)] - Candida albicans (Yeast).
FAS1_YARLI FATTY ACID SYNTHASE, SUBUNIT BETA (EC 2.3.1.86) [INCLUDES: 3- HYDROXYPALMITOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE (EC 4.2.1.61); ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH] (EC 1.3.1.9); [ACYL- CARRIER-PROTEIN] ACETYLTRANSFERASE (EC 2.3.1.38); [ACYL-CARRIER- PROTEIN] MALONYLTRANSFERASE (EC 2.3.1.39); S-ACYL FATTY ACID SYNTHASE THIOESTERASE (EC 3.1.2.14)] - Yarrowia lipolytica (Candida lipolytica).
FAS1_YEAST FATTY ACID SYNTHASE, SUBUNIT BETA (EC 2.3.1.86) [INCLUDES: 3- HYDROXYPALMITOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE (EC 4.2.1.61); ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH] (EC 1.3.1.9); [ACYL- CARRIER-PROTEIN] ACETYLTRANSFERASE (EC 2.3.1.38); [ACYL-CARRIER- PROTEIN] MALONYLTRANSFERASE (EC 2.3.1.39); S-ACYL FATTY ACID SYNTHASE THIOESTERASE (EC 3.1.2.14)] - Saccharomyces cerevisiae (Baker's yeast).
P78616 FATTY ACID SYNTHASE, BETA SUBUNIT - Emericella nidulans (Aspergillus nidulans).
P78799 FATTY ACID SYNTHETASE - Schizosaccharomyces pombe (Fission yeast).
P95029 RV2524C - Mycobacterium tuberculosis.
Q04846 FATTY ACID SYNTHASE (EC 2.3.1.85) (CONTAINS: EC 2.3.1.38, EC 2.3.1.39, EC 2.3.1.41, EC 1.1.1.100, EC 4.2.1.60, EC 4.2.1.61, EC 1.3.1.10, AND EC 3.1.2.14) - Corynebacterium ammoniagenes (Brevibacterium ammoniagenes).
Q05747 FATTY ACID SYNTHASE BETA SUBUNIT - Saccharomyces cerevisiae (Baker's yeast).
Q59497 FATTY-ACID SYNTHASE (EC 2.3.1.85) - Corynebacterium ammoniagenes (Brevibacterium ammoniagenes).
Q92215 PUTATIVE FATTY ACID SYNTHASE BETA - Cochliobolus carbonum (Bipolaris zeicola).
Q9UUG0 FATTY ACID SYNTHASE, SUBUNIT BETA - Schizosaccharomyces pombe (Fission yeast).
Q9X7E2 PUTATIVE TYPE I FATTY ACID SYNTHASE - Mycobacterium leprae.
STCK_EMENI PUTATIVE STERIGMATOCYSTIN BIOSYNTHESIS FATTY ACID SYNTHASE BETA SUBUNIT - Emericella nidulans (Aspergillus nidulans).
Q48926 FATTY ACID SYNTHASE - Mycobacterium bovis.
O53664 HYPOTHETICAL 30.2 KDA PROTEIN - Mycobacterium tuberculosis.
O59897 POLYKETIDE SYNTHASE - Aspergillus fumigatus (Sartorya fumigata).
O60026 POLYKETIDE SYNTHASE - Aspergillus fumigatus (Sartorya fumigata).
O69502 HYPOTHETICAL 30.5 KDA PROTEIN - Mycobacterium leprae.
|
| Scan History | SPTR39_14f 3 25 NSINGLE
|
| Initial Motifs | Motif 1 width=21
Element Seqn Id St Int Rpt
TKFSQLLGRAPLMVAGMTPTT FAS1_CANAL 568 568 -
TKFSKLIGRPPLLVPGMTPCT FAS1_YEAST 581 581 -
TKFSRLTGRAPIMVAGMTPTT FAS1_YARLI 582 582 -
TKMTRLLGTPHVMVAGMTPTT STCK_EMENI 443 443 -
Motif 2 width=19
Element Seqn Id St Int Rpt
VSASLNAGYHIELAGGGYF FAS1_CANAL 594 5 -
VAATTNAGYTIELAGGGYF FAS1_YEAST 607 5 -
VAATMNSGYHIELGGGGYF FAS1_YARLI 608 5 -
VAAIIQADYHVEFACGGYY STCK_EMENI 469 5 -
Motif 3 width=19
Element Seqn Id St Int Rpt
KPGSVDAISQVIAIAKAHP FAS1_CANAL 693 80 -
KPGSIDAISQVINIAKAHP FAS1_YEAST 706 80 -
KPGSIEAISSVIRIAKANP FAS1_YARLI 707 80 -
KPGSVDAIDRVLTIARQYP STCK_EMENI 569 81 -
Motif 4 width=20
Element Seqn Id St Int Rpt
FPIVLQWTGGRGGGHHSFED FAS1_CANAL 713 1 -
FPIALQWTGGRGGGHHSFED FAS1_YEAST 726 1 -
FPIILQWTGGRGGGHHSFED FAS1_YARLI 727 1 -
LPVGIQWTGGRAGGHHSCED STCK_EMENI 589 1 -
Motif 5 width=19
Element Seqn Id St Int Rpt
DLQEMTYKEVANRLVELMY FAS1_CANAL 900 167 -
DLATMTYEEVAKRLVELMF FAS1_YEAST 913 167 -
DLEDLTYAEVIQRLVDLMY FAS1_YARLI 915 168 -
EIEELSYRQVLRRLCQLTY STCK_EMENI 783 174 -
Motif 6 width=25
Element Seqn Id St Int Rpt
QKPVPFVPVLDERFEFFFKKDSLWQ FAS1_CANAL 1000 81 -
QKPVPFVPVLDRRFEIFFKKDSLWQ FAS1_YEAST 1012 80 -
QKPVPFIPVLDDNFEFFFKKDSLWQ FAS1_YARLI 1016 82 -
QKPVPFIPRLDADFQTWFKKDSLWQ STCK_EMENI 880 78 -
Motif 7 width=23
Element Seqn Id St Int Rpt
PGTNEPYAIVSGDYNPIHVSRVF FAS1_CANAL 1533 508 -
PSTNEPYARVSGDLNPIHVSRHF FAS1_YEAST 1547 510 -
PSSNEPYAGVSGDYNPIHVSRAF FAS1_YARLI 1568 527 -
PAQSEGYAMVSGDTNPIHVCPLF STCK_EMENI 1430 525 -
Motif 8 width=22
Element Seqn Id St Int Rpt
FAAYAKLPGTITHGMYSSASIR FAS1_CANAL 1555 -1 -
FASYANLPGTITHGMFSSASVR FAS1_YEAST 1569 -1 -
FASYASLPGTITQGMYSSAAVR FAS1_YARLI 1590 -1 -
FSRFAGLGQPVVHGLHLSATVR STCK_EMENI 1452 -1 -
Motif 9 width=20
Element Seqn Id St Int Rpt
EAEIEQPTTTYVFTGQGSQE FAS1_CANAL 1641 64 -
EAEIEQPVTTFVFTGQGSQE FAS1_YEAST 1654 63 -
EAEVEQPISTFVFTGQGSQE FAS1_YARLI 1676 64 -
EAVLEQAQTTYVFTGQGTQE STCK_EMENI 1538 64 -
Motif 10 width=24
Element Seqn Id St Int Rpt
GMGMELYNSSEVAREVWDKADRHF FAS1_CANAL 1662 1 -
GMGMDLYKTSKAAQDVWNRADNHF FAS1_YEAST 1675 1 -
GMGMDLYASSEVAKKVWDKADEHF FAS1_YARLI 1697 1 -
GMGMALYDTNAAARAVWDRAERHF STCK_EMENI 1559 1 -
Motif 11 width=20
Element Seqn Id St Int Rpt
GLIPSDIMFAGHSLGEYSAL FAS1_CANAL 1784 98 -
GLIPADATFAGHSLGEYAAL FAS1_YEAST 1796 97 -
GLVPVDATFAGHSLGEYSAL FAS1_YARLI 1820 99 -
GVVQTQAIFAGHSLGEYSSL STCK_EMENI 1672 89 -
Motif 12 width=22
Element Seqn Id St Int Rpt
FYRGMTMQVAVPRDELGRSNYG FAS1_CANAL 1820 16 -
FYRGMTMQVAVPRDELGRSNYG FAS1_YEAST 1832 16 -
FYRGMTMQVAVPRDAQGRSNYG FAS1_YARLI 1856 16 -
LYRGLKMQNTLPRNANGRTDYG STCK_EMENI 1708 16 -
|
| Final Motifs | Motif 1 width=21
Element Seqn Id St Int Rpt
TKFSQLLGRAPLMVAGMTPTT FAS1_CANAL 568 568 -
TKFSKLIGRPPLLVPGMTPCT FAS1_YEAST 581 581 -
TKMSRLLGIPPIMVAGMTPTT P78616 592 592 -
TKFSRLTGRAPIMVAGMTPTT FAS1_YARLI 582 582 -
TKFSKLIGRPPLLVPGMTPCT Q05747 581 581 -
TRLSRMLGLPPLWVAGMTPTS P78799 571 571 -
TRLSRMLGLPPLWVAGMTPTS Q9UUG0 571 571 -
TKMSRLLGLPPIMVGGMTPTT Q92215 582 582 -
TKFTRLTGRSPILLAGMTPTT P95029 409 409 -
TKFTRLTGRSPILLAGMTPTT Q9X7E2 409 409 -
TKMTRLLGTPHVMVAGMTPTT STCK_EMENI 443 443 -
TRFTELTGYSPVVLAGMTPST Q04846 378 378 -
TRFSEWTGMSPIILGGMTPTT Q59497 365 365 -
Motif 2 width=19
Element Seqn Id St Int Rpt
VSASLNAGYHIELAGGGYF FAS1_CANAL 594 5 -
VAATTNAGYTIELAGGGYF FAS1_YEAST 607 5 -
VAATMNAGYHIELAGGGYY P78616 618 5 -
VAATMNSGYHIELGGGGYF FAS1_YARLI 608 5 -
VAATTNAGYTIELAGGGYF Q05747 607 5 -
CSAIAKAGFTYELAGGGYF P78799 597 5 -
CSAIAKAGFTYELAGGGYF Q9UUG0 597 5 -
VAATMNAGYHIELAAGGYS Q92215 608 5 -
VAAAANAGHWAELAGGGQV P95029 435 5 -
VAAAANAGHWAELAGGGQV Q9X7E2 435 5 -
VAAIIQADYHVEFACGGYY STCK_EMENI 469 5 -
VAAAANAGFWAELAGGGQV Q04846 404 5 -
VAAAANGGYWSEMAGGGQY Q59497 391 5 -
Motif 3 width=19
Element Seqn Id St Int Rpt
KPGSVDAISQVIAIAKAHP FAS1_CANAL 693 80 -
KPGSIDAISQVINIAKAHP FAS1_YEAST 706 80 -
KPGSVDAIQQVINIAKANP P78616 717 80 -
KPGSIEAISSVIRIAKANP FAS1_YARLI 707 80 -
KPGSIDAISQVINIAKAHP Q05747 706 80 -
KPGSVEAVNAVISIAKANP P78799 696 80 -
KPGSVEAVNAVISIAKANP Q9UUG0 696 80 -
KPGPTTAIDAVIEIAQANP Q92215 707 80 -
KPGTIEQIRSVIRIATEVP P95029 540 86 -
KPGTIEQIRSVIRIATEMS Q9X7E2 540 86 -
KPGSVDAIDRVLTIARQYP STCK_EMENI 569 81 -
KPGAVRHVHQVLAIADDLP Q04846 509 86 -
KPGTTKQIQDCVAIAADNP Q59497 496 86 -
Motif 4 width=20
Element Seqn Id St Int Rpt
FPIVLQWTGGRGGGHHSFED FAS1_CANAL 713 1 -
FPIALQWTGGRGGGHHSFED FAS1_YEAST 726 1 -
FPVILQWTGGRGGGHHSFED P78616 737 1 -
FPIILQWTGGRGGGHHSFED FAS1_YARLI 727 1 -
FPIALQWTGGRGGGHHSFED Q05747 726 1 -
FPIVLQWTGGRAGGHHSFED P78799 716 1 -
FPIVLQWTGGRAGGHHSFED Q9UUG0 716 1 -
FPVFLQWTGGRSGGHHSNED Q92215 727 1 -
KPVIMHVEGGRAGGHHSWED P95029 560 1 -
KPVIMHVEGGRAGGHHSWED Q9X7E2 560 1 -
LPVGIQWTGGRAGGHHSCED STCK_EMENI 589 1 -
TTVIMQVEGGKAGGHHSWED Q04846 529 1 -
HRVIIQIEDAHAGGHHSWVD Q59497 516 1 -
Motif 5 width=19
Element Seqn Id St Int Rpt
DLQEMTYKEVANRLVELMY FAS1_CANAL 900 167 -
DLATMTYEEVAKRLVELMF FAS1_YEAST 913 167 -
DLEDMTYAEVVHRMVDLMY P78616 925 168 -
DLEDLTYAEVIQRLVDLMY FAS1_YARLI 915 168 -
DLATMTYEEVAKRLVELMF Q05747 913 167 -
SVEDMTYAELLYRAIDLMY P78799 914 178 -
SVEDMTYAELLYRAIDLMY Q9UUG0 914 178 -
ELRDMTYAEVLRRMVQLLY Q92215 915 168 -
DVADMTYLQWLRRYVELAI P95029 730 150 -
DVSEMTYLQWLQRYVELTI Q9X7E2 730 150 -
EIEELSYRQVLRRLCQLTY STCK_EMENI 783 174 -
DINAMTYAEWLARYVEVSY Q04846 704 155 -
DLSEMTYEDWVARFAERAY Q59497 689 153 -
Motif 6 width=25
Element Seqn Id St Int Rpt
QKPVPFVPVLDERFEFFFKKDSLWQ FAS1_CANAL 1000 81 -
QKPVPFVPVLDRRFEIFFKKDSLWQ FAS1_YEAST 1012 80 -
QKPVPFVPSLDENFEYWFKKDSLWQ P78616 1025 81 -
QKPVPFIPVLDDNFEFFFKKDSLWQ FAS1_YARLI 1016 82 -
QKPVPFVPVLDRRFEIFFKKDSLWQ Q05747 1012 80 -
QKPVPFIPAIDDTFEFYFKKDSLWQ P78799 1014 81 -
QKPVPFIPAIDDTFEFYFKKDSLWQ Q9UUG0 1014 81 -
QKPVPFVPALDEDFEFFFKKDSLWQ Q92215 1015 81 -
GKPVNFVPVIDQDVRRWWRSDSLWQ P95029 840 91 -
GKPVNFVPVIDKDVRRWWRSDSLWQ Q9X7E2 840 91 -
QKPVPFIPRLDADFQTWFKKDSLWQ STCK_EMENI 880 78 -
GKPPAFVPVIDSDVRRWWRQDSLWQ Q04846 800 77 -
VKPMPWTTAIDGDLKEWFAKDTLWQ Q59497 785 77 -
Motif 7 width=23
Element Seqn Id St Int Rpt
PGTNEPYAIVSGDYNPIHVSRVF FAS1_CANAL 1533 508 -
PSTNEPYARVSGDLNPIHVSRHF FAS1_YEAST 1547 510 -
PASNETYARVSGDYNPIHVSRVF P78616 1572 522 -
PSSNEPYAGVSGDYNPIHVSRAF FAS1_YARLI 1568 527 -
PSTNEPYARVSGDLNPIHVSRHF Q05747 1547 510 -
PPTNSPYAEVSGDYNPIHVSPTF P78799 1563 524 -
PPTNSPYAEVSGDYNPIHVSPTF Q9UUG0 1563 524 -
PSSNEAYARTSGDLNPIHVSRTF Q92215 1565 525 -
PVDMRPFAVVSGDHNPIHTDRAA P95029 1217 352 -
PIDMRPFAVVSGDHNPIHTDRTA Q9X7E2 1219 354 -
PAQSEGYAMVSGDTNPIHVCPLF STCK_EMENI 1430 525 -
PASMHPFAVVTGDRNPIHVSAAA Q04846 1163 338 -
PSDMTPFALVSGDYNPIHTSTNA Q59497 1185 375 -
Motif 8 width=22
Element Seqn Id St Int Rpt
FAAYAKLPGTITHGMYSSASIR FAS1_CANAL 1555 -1 -
FASYANLPGTITHGMFSSASVR FAS1_YEAST 1569 -1 -
FSSYANLPGTITHGMYTSAAVR P78616 1594 -1 -
FASYASLPGTITQGMYSSAAVR FAS1_YARLI 1590 -1 -
FASYANLLGTITHGMFSSTSVR Q05747 1569 -1 -
AFVELPGTHGITHGMYTSAAAR P78799 1587 1 -
AFVELPGTHGITHGMYTSAAAR Q9UUG0 1587 1 -
FAEYAGLPGLITHGMYCSAAIQ Q92215 1587 -1 -
AALLAGLESPIVHGMWLSAAAQ P95029 1239 -1 -
AALLAGLESPIVHGMWLSAAAQ Q9X7E2 1241 -1 -
FSRFAGLGQPVVHGLHLSATVR STCK_EMENI 1452 -1 -
ARLAGLENGVIVHGMWTSAIGQ Q04846 1186 0 -
AARLVNLDAPLVHGMWLSATAQ Q59497 1207 -1 -
Motif 9 width=20
Element Seqn Id St Int Rpt
EAEIEQPTTTYVFTGQGSQE FAS1_CANAL 1641 64 -
EAEIEQPVTTFVFTGQGSQE FAS1_YEAST 1654 63 -
EAEVEQPVTAYVFTGQGSQE P78616 1680 64 -
EAEVEQPISTFVFTGQGSQE FAS1_YARLI 1676 64 -
EAEIEQPVTTFVFTGQGSQE Q05747 1654 63 -
TAEVEQPVSAYVFTGQGSQE P78799 1673 64 -
TAEVEQPVSAYVFTGQGSQE Q9UUG0 1673 64 -
EAKITQKMTTYVFTGQGSQE Q92215 1673 64 -
SARLAAPKTVYAFPGQGIQH P95029 1324 63 -
TARLAAPKTVYAFPGQGIQH Q9X7E2 1326 63 -
EAVLEQAQTTYVFTGQGTQE STCK_EMENI 1538 64 -
TATMAAPRTFYGFPGQGIQS Q04846 1268 60 -
QALMAQPRTAYVYPGQGIQA Q59497 1285 56 -
Motif 10 width=24
Element Seqn Id St Int Rpt
GMGMELYNSSEVAREVWDKADRHF FAS1_CANAL 1662 1 -
GMGMDLYKTSKAAQDVWNRADNHF FAS1_YEAST 1675 1 -
GMGMELYATSPVAKEVWDRPSFHW P78616 1701 1 -
GMGMDLYASSEVAKKVWDKADEHF FAS1_YARLI 1697 1 -
GMGMDLYKTSKAAQDVWNRADNHF Q05747 1675 1 -
GMGMDLYASSPVARKIWDSADKHF P78799 1694 1 -
GMGMDLYASSPVARKIWDSADKHF Q9UUG0 1694 1 -
GMGMDLYNQCPAAREVWDRGDKYF Q92215 1694 1 -
GMGMEVRARSKAARKVWDTADKFT P95029 1345 1 -
GMGMDVRARSKAARRVWDDADKFT Q9X7E2 1347 1 -
GMGMALYDTNAAARAVWDRAERHF STCK_EMENI 1559 1 -
GMGMESYASSSAAREVWERADAHT Q04846 1289 1 -
GMGRGDRDASAAAREVWRRADRHT Q59497 1306 1 -
Motif 11 width=20
Element Seqn Id St Int Rpt
GLIPSDIMFAGHSLGEYSAL FAS1_CANAL 1784 98 -
GLIPADATFAGHSLGEYAAL FAS1_YEAST 1796 97 -
GLVQRDSSFAGHSLGEYSAL P78616 1821 96 -
GLVPVDATFAGHSLGEYSAL FAS1_YARLI 1820 99 -
GLIPADATFAGHSLGEYAAL Q05747 1796 97 -
GLVQNDCAFAGHSLGEYSAL P78799 1816 98 -
GLVQNDCAFAGHSLGEYSAL Q9UUG0 1816 98 -
GLVDGNCYYAGHSLGEFSAL Q92215 1816 98 -
GAFVEGAIACGHSVGEYTAL P95029 1426 57 -
GAFVEGAIACGHSVGEYTAL Q9X7E2 1428 57 -
GVVQTQAIFAGHSLGEYSSL STCK_EMENI 1672 89 -
GVKSQDTYFAGHSVGEYNAL Q04846 1370 57 -
DALGTNSMYAGHSLGEYTAL Q59497 1387 57 -
Motif 12 width=22
Element Seqn Id St Int Rpt
FYRGMTMQVAVPRDELGRSNYG FAS1_CANAL 1820 16 -
FYRGMTMQVAVPRDELGRSNYG FAS1_YEAST 1832 16 -
FYRGLTMQVAVERDEQGRSNYS P78616 1857 16 -
FYRGMTMQVAVPRDAQGRSNYG FAS1_YARLI 1856 16 -
FYRGMTMQVAVPRDELGRSNYG Q05747 1832 16 -
FLRGLTMQNAVHRDELGRSDYG P78799 1852 16 -
FLRGLTMQNAVHRDELGRSDYG Q9UUG0 1852 16 -
FYRGLTMQKAVNRDESGRSNYS Q92215 1852 16 -
FHRGSKMHDIVPRDELGRSNYR P95029 1462 16 -
FHRGSKMHDIVLRDELGRSNYR Q9X7E2 1464 16 -
LYRGLKMQNTLPRNANGRTDYG STCK_EMENI 1708 16 -
YARGLTMHRLVDRDAEGNSNYG Q04846 1406 16 -
YSRGSAMGTLVERDENGNSNYG Q59497 1423 16 -
|