| Literature References | 1. GOLDEN, B.L., RAMAKRISHNAN, V. AND WHITE, S.W.
Ribosomal protein L: structural evidence of gene duplication from a
primitive RNA binding protein.
EMBO J. 12 4901-4908 (1993).
2. LAN, Q., NIU, L.L. AND FALLON, A.M.
Mosquito ribosomal protein rpL31 resembles rat rpL34: cDNA and deduced
amino acid sequence.
BIOCHIM.BIOPHYS.ACTA 1218 460-462 (1994).
3. GAO, J., KIM, S.R., CHUNG, Y.Y., LEE, J.M. AND AN, G.
Developmental and environmental regulation of two ribosomal protein genes
in tobacco.
PLANT MOL.BIOL. 25 761-770 (1994).
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| Documentation | Protein synthesis is co-ordinated in all cells by ribosomes, ribonucleo-
protein particles containing more than 50 different proteins and several
large RNAs [1]. Low resolution models show the protein arrangement in both
the large and small ribosomal subunits, but higher resolution structures are
required to reveal the detailed mechanistic functioning of the complex [2].
Ribosomal protein L34 contains 89-129 amino acid residues. On the basis of
sequence similarity, the ribosomal L34 family can be shown to include:
mammalian L34; mosquito L31 [1]; plant L34 [2]; yeast putative ribosomal
protein YIL052c; and Methanococcus jannaschii MJ0655.
RIBOSOMALL34 is a 4-element fingerprint that provides a signature for
ribosomal L34 proteins. The fingerprint was derived from an initial
alignment of 10 sequences: the motifs were drawn from conserved regions
spanning virtually the full alignment length - motif 1 spans the region
encoded by PROSITE pattern RIBOSOMAL_L34E (PS01145). Two iterations on
SPTR37_10f were required to reach convergence, at which point a true set
comprising 14 sequences was identified.
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