SPRINT Home UMBER Home Contents Standard Search Advanced Search Relation Search

==SPRINT==> PRINTS View



  selected as


PR01231

Identifier
HCO3TRNSPORT  [View Relations]  [View Alignment]  
Accession
PR01231
No. of Motifs
8
Creation Date
06-DEC-1999
Title
HCO3- transporter superfamily signature
Database References

PFAM; PF00955 Anion_Exchanger
PRODOM; PD001455
INTERPRO; IPR003020
Literature References
1. KOPITO, R.R.
Molecular biology of the anion exchanger gene family.
INT.REV.CYTOL. 123 177-199 (1990).
 
2. BORON, W.F., FONG, P., HEDIGER, M.A., BOULPAEP, E.L. AND ROMERO, M.F.
The electrogenic Na/HCO3 cotransporter.
WIEN.KLIN.WOCHENSCHR. 109 445-456 (1997).
 
3. BURNHAM, C.E., HASSANE, A., WANG, Z., SHULL, G.E. AND SOLEIMANI, M.
Cloning and functional expression of a human kidney Na+:HCO3-
cotransporter.
J.BIOL.CHEM. 272 19111-19114 (1997).

Documentation
Bicarbonate (HCO3-) transport mechanisms are the principal regulators of pH
in animal cells. Such transport also plays a vital role in acid-base
movements in the stomach, pancreas, intestine, kidney, reproductive organs
and the central nervous system. Functional studies have suggested four
different HCO3- transport modes. Anion exchanger proteins exchange HCO3-
for Cl- in a reversible, electroneutral manner [1]. Na+/HCO3- co-transport
proteins mediate the coupled movement of Na+ and HCO3- across plasma
membranes, often in an electrogenic manner [2]. Na- driven Cl-/HCO3-
exchange and K+/HCO3- exchange activities have also been detected in 
certain cell types, although the molecular identities of the proteins
responsible remain to be determined.
 
Sequence analysis of the two families of HCO3- transporters that have been
cloned to date (the anion exchangers and Na+/HCO3- co-transporters) reveals
that they are homologous. This is not entirely unexpected, given that they
both transport HCO3- and are inhibited by a class of pharmacological agents
called disulphonic stilbenes [3]. They share around ~25-30% sequence
identity, which is distributed along their entire sequence length, and have
similar predicted membrane topologies, suggesting they have ~10
transmembrane (TM) domains.
 
HCO3TRNSPORT is an 8-element fingerprint that provides a signature for the
HCO3- transporter superfamily. The fingerprint was derived from an initial
alignment of 18 sequences: the motifs were drawn from conserved regions
from the central portion of the alignment - motif 1 lies near the end of
the long presumed-cytoplasmic N-terminus; motifs 2-3 encode most of the
first TM domain; motif 4 spans the end of fourth TM domain and the start 
of the following cytoplasmic loop; motif 5 encodes ~2/3 of the fifth TM 
domain; motif 6 lies on the sixth TM domain; motif 7 encodes a portion of
the seventh TM domain; and motif 8 lies on the putative extracellular loop,
between TM domains 7 and 8. Two iterations on SPTR37_10f were required to
reach convergence, at which point a true set comprising 28 sequences was
identified.
Summary Information
28 codes involving  8 elements
0 codes involving 7 elements
0 codes involving 6 elements
0 codes involving 5 elements
0 codes involving 4 elements
0 codes involving 3 elements
0 codes involving 2 elements
Composite Feature Index
82828282828282828
700000000
600000000
500000000
400000000
300000000
200000000
12345678
True Positives
B3A2_HUMAN    B3A2_MOUSE    B3A2_RABIT    B3A2_RAT      
B3A3_HUMAN B3A3_MOUSE B3A3_RAT B3AT_CHICK
B3AT_HUMAN B3AT_MOUSE B3AT_ONCMY B3AT_RAT
O13134 O15153 O18917 O35422
O54815 O60350 O61304 O88343
O95233 O97915 Q20642 Q90579
Q90710 Q91452 Q99654 Q9Z0S8
Sequence Titles
B3A2_HUMAN  ANION EXCHANGE PROTEIN 2 (NON-ERYTHROID BAND 3-LIKE PROTEIN) (BND3L) - HOMO SAPI 
B3A2_MOUSE ANION EXCHANGE PROTEIN 2 (NON-ERYTHROID BAND 3-LIKE PROTEIN) (B3RP) - MUS MUSCUL
B3A2_RABIT ANION EXCHANGE PROTEIN 2 (NON-ERYTHROID BAND 3-LIKE PROTEIN) (B3RP) - ORYCTOLAGU
B3A2_RAT ANION EXCHANGE PROTEIN 2 (NON-ERYTHROID BAND 3-LIKE PROTEIN) (B3RP) - RATTUS NOR
B3A3_HUMAN ANION EXCHANGE PROTEIN 3 (CARDIAC/BRAIN BAND 3-LIKE PROTEIN) (CAE3/BAE3) - HOMO
B3A3_MOUSE ANION EXCHANGE PROTEIN 3 (NEURONAL BAND 3-LIKE PROTEIN) - MUS MUSCULUS (MOUSE).
B3A3_RAT ANION EXCHANGE PROTEIN 3 (NEURONAL BAND 3-LIKE PROTEIN) - RATTUS NORVEGICUS (RAT
B3AT_CHICK BAND 3 ANION TRANSPORT PROTEIN - GALLUS GALLUS (CHICKEN).
B3AT_HUMAN BAND 3 ANION TRANSPORT PROTEIN (ANION EXCHANGE PROTEIN 1) (AE 1) - HOMO SAPIENS
B3AT_MOUSE BAND 3 ANION EXCHANGE PROTEIN (MEB3) - MUS MUSCULUS (MOUSE).
B3AT_ONCMY BAND 3 ANION EXCHANGE PROTEIN - ONCORHYNCHUS MYKISS (RAINBOW TROUT) (SALMO GAIRD
B3AT_RAT BAND 3 ANION EXCHANGE PROTEIN, KIDNEY - RATTUS NORVEGICUS (RAT).
O13134 ELECTROGENIC NA+ BICARBONATE COTRANSPORTER - AMBYSTOMA TIGRINUM (TIGER SALAMANDE
O15153 SODIUM BICARBONATE COTRANSPORTER - HOMO SAPIENS (HUMAN).
O18917 ANION EXCHANGER 3 BRAIN ISOFORM - ORYCTOLAGUS CUNICULUS (RABBIT).
O35422 SODIUM BICARBONATE COTRANSPORTER - RATTUS NORVEGICUS (RAT).
O54815 ELECTROGENIC NA+ BICARBONATE COTRANSPORTER - RATTUS NORVEGICUS (RAT).
O60350 SODIUM BICARBONATE COTRANSPORTER2 - HOMO SAPIENS (HUMAN).
O61304 HCO3 TRANSPORTER - CAENORHABDITIS ELEGANS.
O88343 PANCREAS SODIUM BICARBONATE COTRANSPORTER - MUS MUSCULUS (MOUSE).
O95233 SODIUM BICARBONATE COTRANSPORTER - HOMO SAPIENS (HUMAN).
O97915 SODIUM BICARBONATE COTRANSPORTER - ORYCTOLAGUS CUNICULUS (RABBIT).
Q20642 F52B5.1 PROTEIN - CAENORHABDITIS ELEGANS.
Q90579 ERYTHROID ANION TRANSPORTER - GALLUS GALLUS (CHICKEN).
Q90710 AE2-1 ANION EXCHANGER - GALLUS GALLUS (CHICKEN).
Q91452 ANION EXCHANGER - ONCORHYNCHUS MYKISS (RAINBOW TROUT) (SALMO GAIRDNERI).
Q99654 AE2 ANION EXCHANGER - HOMO SAPIENS (HUMAN).
Q9Z0S8 AE2 ANION EXCHANGER - CAVIA PORCELLUS (GUINEA PIG).
Scan History
SPTR37_10f 2  100  NSINGLE    
Initial Motifs
Motif 1  width=13
Element Seqn Id St Int Rpt
PVPVRFLFLLLGP B3A2_MOUSE 546 546 -
PVPVRFLFLLLGP B3A2_RABIT 546 546 -
PVPVRFLFLLLGP B3A2_RAT 547 547 -
PVPVRFLFLLLGP B3A2_HUMAN 550 550 -
PVPIRFLFVLLGP B3AT_HUMAN 259 259 -
PVPVRFLFVMLGP B3A3_RAT 548 548 -
PVPVRFLFVMLGP B3A3_MOUSE 548 548 -
PEPVGFLLVLLGP B3AT_MOUSE 272 272 -
PEPVSFLLVLLGP B3AT_RAT 272 272 -
PVPVRFVFVLVGP B3AT_ONCMY 246 246 -
PVPTRFLFILLGP O15153 274 274 -
PVPTRFLFILLGP O35422 274 274 -
PVPTRFLFILLGP O54815 274 274 -
PVPTRFLFILLGP O88343 318 318 -
PVPTRFLFILLGP O13134 275 275 -
PLPVRFVLTVLGP B3AT_CHICK 266 266 -
PVPTRFLFLLLGP O60350 248 248 -
PVPTRFIFLLLGP O61304 275 275 -

Motif 2 width=10
Element Seqn Id St Int Rpt
SDFRDALDPQ B3A2_MOUSE 694 135 -
SDFRDALDPQ B3A2_RABIT 694 135 -
SDFRDALDPQ B3A2_RAT 695 135 -
SDFRDALDPQ B3A2_HUMAN 697 134 -
SDITDAFSPQ B3AT_HUMAN 395 123 -
SDLRDALHSQ B3A3_RAT 697 136 -
SDLRDALHSQ B3A3_MOUSE 697 136 -
SDITDALSPQ B3AT_MOUSE 414 129 -
SDITDALSPQ B3AT_RAT 412 127 -
SDFTDALDPQ B3AT_ONCMY 384 125 -
SDFYDALNIQ O15153 415 128 -
SDFYDALNIQ O35422 415 128 -
SDFYDALNIQ O54815 415 128 -
SDFYDALNIQ O88343 459 128 -
SDFYDALSIQ O13134 414 126 -
SDIRDALNPQ B3AT_CHICK 408 129 -
SDFKDALSLQ O60350 384 123 -
SDFTDAFNLQ O61304 418 130 -

Motif 3 width=12
Element Seqn Id St Int Rpt
AITFGGLLGEKT B3A2_MOUSE 719 15 -
AITFGGLLGEKT B3A2_RABIT 719 15 -
AITFGGLLGEKT B3A2_RAT 720 15 -
AITFGGLLGEKT B3A2_HUMAN 722 15 -
AITFGGLLGEKT B3AT_HUMAN 420 15 -
AITFGGLLGEKT B3A3_RAT 722 15 -
AITFGGLLGEKT B3A3_MOUSE 722 15 -
AVTFGGLLGEKT B3AT_MOUSE 439 15 -
AVTFGGLLGEKT B3AT_RAT 437 15 -
AITFGGLLADKT B3AT_ONCMY 409 15 -
AITFGGLLGDAT O15153 440 15 -
AITFGGLLGDAT O35422 440 15 -
AITFGGLLGDAT O54815 440 15 -
AITFGGLLGDAT O88343 484 15 -
AITFGGLLGDAT O13134 439 15 -
AITFGGLLGEKT B3AT_CHICK 433 15 -
VITFGGLLGEAT O60350 409 15 -
IVTFGGLLEEAT O61304 443 15 -

Motif 4 width=13
Element Seqn Id St Int Rpt
SFLVRFVSRFTQE B3A2_MOUSE 809 78 -
SFLVRFVSRFTQE B3A2_RABIT 809 78 -
SFLVRFVSRFTQE B3A2_RAT 810 78 -
SFLVRFVSRFTRE B3A2_HUMAN 812 78 -
SFLVRFISRYTQE B3AT_HUMAN 510 78 -
SFLVRYISPFTQE B3A3_RAT 812 78 -
TFLVRYISPFTQE B3A3_MOUSE 812 78 -
SFLVQYISRYTQE B3AT_MOUSE 529 78 -
SFLVQYISRYTQE B3AT_RAT 527 78 -
SFLVKFISRFTQE B3AT_ONCMY 499 78 -
SFLVQYFTRFTEE O15153 530 78 -
SFLVQYFTRFTEE O35422 530 78 -
SFLVQYFTRFTEE O54815 530 78 -
SFLVQYFTRFTEE O88343 574 78 -
SFLVKYFTRFTEE O13134 529 78 -
TVLVRYLSRYTQE B3AT_CHICK 523 78 -
SSLVCYITRFTEE O60350 499 78 -
SALVSFITRFTEE O61304 533 78 -

Motif 5 width=13
Element Seqn Id St Int Rpt
IFIYETFYKLIKI B3A2_MOUSE 830 8 -
IFIYETFYKLIKI B3A2_RABIT 830 8 -
IFIYETFYKLIKI B3A2_RAT 831 8 -
IFIYETFYKLVKI B3A2_HUMAN 833 8 -
IFIYETFSKLIKI B3AT_HUMAN 531 8 -
IFIYETFHKLYKV B3A3_RAT 833 8 -
IFIYETFHKLYKV B3A3_MOUSE 833 8 -
IFIYETFSKLIKI B3AT_MOUSE 550 8 -
IFIYETFSKLIKI B3AT_RAT 548 8 -
IFIYETFSKLGKI B3AT_ONCMY 520 8 -
IFIYDAFKKMIKL O15153 551 8 -
IFIYDAFKKMIKL O35422 551 8 -
IFIYDAFKKMIKL O54815 551 8 -
IFIYDAFKKMIKL O88343 595 8 -
IFIYDAFKKMIKL O13134 550 8 -
IFIYETFAKLVTI B3AT_CHICK 544 8 -
IFIYEALEKLFDL O60350 520 8 -
IFIYEAIMKLVKI O61304 554 8 -

Motif 6 width=10
Element Seqn Id St Int Rpt
DFGVPIAILI B3A2_MOUSE 933 90 -
DFGVPIAILI B3A2_RABIT 933 90 -
DFGVPIAILI B3A2_RAT 930 86 -
DFGVPIAILI B3A2_HUMAN 936 90 -
DFGVPISILI B3AT_HUMAN 607 63 -
DFGIPISILV B3A3_RAT 924 78 -
DFGIPISILV B3A3_MOUSE 924 78 -
DFGVPISILI B3AT_MOUSE 625 62 -
DFGVPISILI B3AT_RAT 623 62 -
DFGVPIAIFF B3AT_ONCMY 620 87 -
DFAIILSILI O15153 685 121 -
DFAIILSILI O35422 685 121 -
DFAIILSILI O54815 685 121 -
DFAIILSILI O88343 729 121 -
DFAIILSILI O13134 685 122 -
DFGVPISIFV B3AT_CHICK 618 61 -
DFAVFLTIVI O60350 647 114 -
DFAVMIAIAS O61304 684 117 -

Motif 7 width=10
Element Seqn Id St Int Rpt
ILIFMETQIT B3A2_MOUSE 1002 59 -
ILIFMETQIT B3A2_RABIT 1002 59 -
ILIFMETQIT B3A2_RAT 999 59 -
ILIFMETQIT B3A2_HUMAN 1005 59 -
ILIFLESQIT B3AT_HUMAN 676 59 -
ILIFMETQIT B3A3_RAT 993 59 -
ILIFMETQIT B3A3_MOUSE 993 59 -
ILIFLESQIT B3AT_MOUSE 694 59 -
ILIFLESQIT B3AT_RAT 692 59 -
ILIFLESQIT B3AT_ONCMY 689 59 -
ILIFMDQQIT O15153 749 54 -
ILIFMDQQIT O35422 749 54 -
ILIFMDQQIT O54815 749 54 -
ILIFMDQQIT O88343 793 54 -
ILIFMDQQIT O13134 749 54 -
ILIFLETQIT B3AT_CHICK 687 59 -
ILIFMDQQIT O60350 711 54 -
ILIFMDQQIT O61304 748 54 -

Motif 8 width=14
Element Seqn Id St Int Rpt
SKKERMLQKGSGFH B3A2_MOUSE 1016 4 -
SKKERMLQKGSGFH B3A2_RABIT 1016 4 -
SKKERMLQKGSGFH B3A2_RAT 1013 4 -
SKKERMLQKGSGFH B3A2_HUMAN 1019 4 -
SKPERKMVKGSGFH B3AT_HUMAN 690 4 -
SQKARRLLKGSGFH B3A3_RAT 1007 4 -
SQKARRLLKGSGFH B3A3_MOUSE 1007 4 -
SKPERKMIKGSGFH B3AT_MOUSE 708 4 -
SKPERKMIKGSGFH B3AT_RAT 706 4 -
SKPERKMVKGSGFH B3AT_ONCMY 703 4 -
NRKEHKLKKGAGYH O15153 763 4 -
NRKEHKLKKGAGYH O35422 763 4 -
NRKEHKLKKGAGYH O54815 763 4 -
NRKEHKLQKGAGYH O88343 807 4 -
NRKEHKLKKGAGYH O13134 763 4 -
SKPERKLVKGSGFH B3AT_CHICK 701 4 -
NRKEHKLKKGAGYH O60350 725 4 -
NRKENKLKKGCGYH O61304 762 4 -
Final Motifs
Motif 1  width=13
Element Seqn Id St Int Rpt
PVPVRFLFLLLGP B3A2_MOUSE 546 546 -
PVPVRFLFLLLGP B3A2_RABIT 546 546 -
PVPVRFLFLLLGP B3A2_RAT 547 547 -
PVPVRFLFLLLGP Q99654 550 550 -
PVPVRFLFLLLGP Q9Z0S8 546 546 -
PVPVRFLFLLLGP B3A2_HUMAN 550 550 -
PVPVRFLFLLLGP Q90710 547 547 -
PVPIRFLFVLLGP B3AT_HUMAN 259 259 -
PVPVRFLFVMLGP B3A3_HUMAN 549 549 -
PVPVRFLFVMLGP B3A3_RAT 548 548 -
PVPVRFLFVMLGP B3A3_MOUSE 548 548 -
PEPVGFLLVLLGP B3AT_MOUSE 272 272 -
PEPVSFLLVLLGP B3AT_RAT 272 272 -
PVPVRFLFVMLGP O18917 550 550 -
PVPVRFVFVLVGP B3AT_ONCMY 246 246 -
PVPVRFVFVLVGP Q91452 240 240 -
PVPTRFLFILLGP O15153 274 274 -
PVPTRFLFILLGP O35422 274 274 -
PVPTRFLFILLGP O54815 274 274 -
PVPTRFLFILLGP O97915 274 274 -
PVPTRFLFILLGP O88343 318 318 -
PVPTRFLFILLGP O13134 275 275 -
PLPVRFVLTVLGP Q90579 188 188 -
PLPVRFVLTVLGP B3AT_CHICK 266 266 -
PVPTRFLFLLLGP O60350 248 248 -
PIPTRFLFILLGP O95233 334 334 -
PVPTRFIFLLLGP O61304 275 275 -
PVPTRFIFLLLGP Q20642 317 317 -

Motif 2 width=10
Element Seqn Id St Int Rpt
SDFRDALDPQ B3A2_MOUSE 694 135 -
SDFRDALDPQ B3A2_RABIT 694 135 -
SDFRDALDPQ B3A2_RAT 695 135 -
SDFRDALDPQ Q99654 698 135 -
SDFRDALDPQ Q9Z0S8 695 136 -
SDFRDALDPQ B3A2_HUMAN 697 134 -
SDFRDALNPQ Q90710 690 130 -
SDITDAFSPQ B3AT_HUMAN 395 123 -
SDLRDALHSQ B3A3_HUMAN 698 136 -
SDLRDALHSQ B3A3_RAT 697 136 -
SDLRDALHSQ B3A3_MOUSE 697 136 -
SDITDALSPQ B3AT_MOUSE 414 129 -
SDITDALSPQ B3AT_RAT 412 127 -
SDLRDALHSQ O18917 699 136 -
SDFTDALDPQ B3AT_ONCMY 384 125 -
SDFTDALDPQ Q91452 378 125 -
SDFYDALNIQ O15153 415 128 -
SDFYDALNIQ O35422 415 128 -
SDFYDALNIQ O54815 415 128 -
SDFYDALNIQ O97915 415 128 -
SDFYDALNIQ O88343 459 128 -
SDFYDALSIQ O13134 414 126 -
SDIRDALNPQ Q90579 330 129 -
SDIRDALNPQ B3AT_CHICK 408 129 -
SDFKDALSLQ O60350 384 123 -
SDYRDALSLQ O95233 468 121 -
SDFTDAFNLQ O61304 418 130 -
SDFTDAFNLQ Q20642 460 130 -

Motif 3 width=12
Element Seqn Id St Int Rpt
AITFGGLLGEKT B3A2_MOUSE 719 15 -
AITFGGLLGEKT B3A2_RABIT 719 15 -
AITFGGLLGEKT B3A2_RAT 720 15 -
AITFGGLLGEKT Q99654 723 15 -
AITFGGLLGEKT Q9Z0S8 720 15 -
AITFGGLLGEKT B3A2_HUMAN 722 15 -
AITFGGLLGEKT Q90710 715 15 -
AITFGGLLGEKT B3AT_HUMAN 420 15 -
AITFGGLLGEKT B3A3_HUMAN 723 15 -
AITFGGLLGEKT B3A3_RAT 722 15 -
AITFGGLLGEKT B3A3_MOUSE 722 15 -
AVTFGGLLGEKT B3AT_MOUSE 439 15 -
AVTFGGLLGEKT B3AT_RAT 437 15 -
AITFGGLLGEKT O18917 724 15 -
AITFGGLLADKT B3AT_ONCMY 409 15 -
AITFGGLLADKT Q91452 403 15 -
AITFGGLLGDAT O15153 440 15 -
AITFGGLLGDAT O35422 440 15 -
AITFGGLLGDAT O54815 440 15 -
AITFGGLLGDAT O97915 440 15 -
AITFGGLLGDAT O88343 484 15 -
AITFGGLLGDAT O13134 439 15 -
AITFGGLLGEKT Q90579 355 15 -
AITFGGLLGEKT B3AT_CHICK 433 15 -
VITFGGLLGEAT O60350 409 15 -
VITFGGLLGEAT O95233 493 15 -
IVTFGGLLEEAT O61304 443 15 -
IVTFGGLLEEAT Q20642 485 15 -

Motif 4 width=13
Element Seqn Id St Int Rpt
SFLVRFVSRFTQE B3A2_MOUSE 809 78 -
SFLVRFVSRFTQE B3A2_RABIT 809 78 -
SFLVRFVSRFTQE B3A2_RAT 810 78 -
SFLVRFVSRFTQE Q99654 813 78 -
SFLVRFGSRFTQE Q9Z0S8 810 78 -
SFLVRFVSRFTRE B3A2_HUMAN 812 78 -
SFLVRFVSRFTQE Q90710 805 78 -
SFLVRFISRYTQE B3AT_HUMAN 510 78 -
SFLVRYISPFTQE B3A3_HUMAN 813 78 -
SFLVRYISPFTQE B3A3_RAT 812 78 -
TFLVRYISPFTQE B3A3_MOUSE 812 78 -
SFLVQYISRYTQE B3AT_MOUSE 529 78 -
SFLVQYISRYTQE B3AT_RAT 527 78 -
TFLVRYISPFTQE O18917 814 78 -
SFLVKFISRFTQE B3AT_ONCMY 499 78 -
SFLVKFISRFTQE Q91452 493 78 -
SFLVQYFTRFTEE O15153 530 78 -
SFLVQYFTRFTEE O35422 530 78 -
SFLVQYFTRFTEE O54815 530 78 -
SFLVQYFTRFTEE O97915 530 78 -
SFLVQYFTRFTEE O88343 574 78 -
SFLVKYFTRFTEE O13134 529 78 -
SVLVRYLSRYTQE Q90579 445 78 -
TVLVRYLSRYTQE B3AT_CHICK 523 78 -
SSLVCYITRFTEE O60350 499 78 -
SSLVCYITRFTEE O95233 583 78 -
SALVSFITRFTEE O61304 533 78 -
SALVSFITRFTEE Q20642 575 78 -

Motif 5 width=13
Element Seqn Id St Int Rpt
IFIYETFYKLIKI B3A2_MOUSE 830 8 -
IFIYETFYKLIKI B3A2_RABIT 830 8 -
IFIYETFYKLIKI B3A2_RAT 831 8 -
IFIYETFYKLVKI Q99654 834 8 -
IFIYETFYKLVKI Q9Z0S8 831 8 -
IFIYETFYKLVKI B3A2_HUMAN 833 8 -
IFIYETFSKLGKI Q90710 826 8 -
IFIYETFSKLIKI B3AT_HUMAN 531 8 -
IFIYETFYKLYKV B3A3_HUMAN 834 8 -
IFIYETFHKLYKV B3A3_RAT 833 8 -
IFIYETFHKLYKV B3A3_MOUSE 833 8 -
IFIYETFSKLIKI B3AT_MOUSE 550 8 -
IFIYETFSKLIKI B3AT_RAT 548 8 -
IFIYETFHKLYKV O18917 835 8 -
IFIYETFSKLGKI B3AT_ONCMY 520 8 -
IFIYETFSKLGKI Q91452 514 8 -
IFIYDAFKKMIKL O15153 551 8 -
IFIYDAFKKMIKL O35422 551 8 -
IFIYDAFKKMIKL O54815 551 8 -
IFIYDAFKKMIKL O97915 551 8 -
IFIYDAFKKMIKL O88343 595 8 -
IFIYDAFKKMIKL O13134 550 8 -
IFIYETFAKLVTI Q90579 466 8 -
IFIYETFAKLVTI B3AT_CHICK 544 8 -
IFIYEALEKLFDL O60350 520 8 -
IFIYEAIEKLIHL O95233 604 8 -
IFIYEAIMKLVKI O61304 554 8 -
IFIYEAIMKLVKI Q20642 596 8 -

Motif 6 width=10
Element Seqn Id St Int Rpt
DFGVPIAILI B3A2_MOUSE 933 90 -
DFGVPIAILI B3A2_RABIT 933 90 -
DFGVPIAILI B3A2_RAT 930 86 -
DFGVPIAILI Q99654 937 90 -
DFGVPIAILI Q9Z0S8 934 90 -
DFGVPIAILI B3A2_HUMAN 936 90 -
DFGVPIAILV Q90710 916 77 -
DFGVPISILI B3AT_HUMAN 607 63 -
DFGIPISILV B3A3_HUMAN 929 82 -
DFGIPISILV B3A3_RAT 924 78 -
DFGIPISILV B3A3_MOUSE 924 78 -
DFGVPISILI B3AT_MOUSE 625 62 -
DFGVPISILI B3AT_RAT 623 62 -
DFGIPISILL O18917 930 82 -
DFGVPIAIFF B3AT_ONCMY 620 87 -
DFGVPIAIFF Q91452 614 87 -
DFAIILSILI O15153 685 121 -
DFAIILSILI O35422 685 121 -
DFAIILSILI O54815 685 121 -
DFAIILSILI O97915 685 121 -
DFAIILSILI O88343 729 121 -
DFAIILSILI O13134 685 122 -
DFGVPISIFV Q90579 540 61 -
DFGVPISIFV B3AT_CHICK 618 61 -
DFAVFLTIVI O60350 647 114 -
DFAVFLTIFT O95233 731 114 -
DFAVMIAIAS O61304 684 117 -
DFAVMIAIAS Q20642 726 117 -

Motif 7 width=10
Element Seqn Id St Int Rpt
ILIFMETQIT B3A2_MOUSE 1002 59 -
ILIFMETQIT B3A2_RABIT 1002 59 -
ILIFMETQIT B3A2_RAT 999 59 -
ILIFMETQIT Q99654 1006 59 -
ILIFMETQIT Q9Z0S8 1003 59 -
ILIFMETQIT B3A2_HUMAN 1005 59 -
ILIFMETQIT Q90710 985 59 -
ILIFLESQIT B3AT_HUMAN 676 59 -
ILIFMETQIT B3A3_HUMAN 998 59 -
ILIFMETQIT B3A3_RAT 993 59 -
ILIFMETQIT B3A3_MOUSE 993 59 -
ILIFLESQIT B3AT_MOUSE 694 59 -
ILIFLESQIT B3AT_RAT 692 59 -
ILIFMETQIT O18917 999 59 -
ILIFLESQIT B3AT_ONCMY 689 59 -
ILIFLESQIT Q91452 683 59 -
ILIFMDQQIT O15153 749 54 -
ILIFMDQQIT O35422 749 54 -
ILIFMDQQIT O54815 749 54 -
ILIFMDQQIT O97915 749 54 -
ILIFMDQQIT O88343 793 54 -
ILIFMDQQIT O13134 749 54 -
ILIFLETQIT Q90579 609 59 -
ILIFLETQIT B3AT_CHICK 687 59 -
ILIFMDQQIT O60350 711 54 -
ILIFMDQQIT O95233 795 54 -
ILIFMDQQIT O61304 748 54 -
ILIFMDQQIT Q20642 790 54 -

Motif 8 width=14
Element Seqn Id St Int Rpt
SKKERMLQKGSGFH B3A2_MOUSE 1016 4 -
SKKERMLQKGSGFH B3A2_RABIT 1016 4 -
SKKERMLQKGSGFH B3A2_RAT 1013 4 -
SKKERMLQKGSGFH Q99654 1020 4 -
SKKERMLQKGSGFH Q9Z0S8 1017 4 -
SKKERMLQKGSGFH B3A2_HUMAN 1019 4 -
SKKERMLQKGSGFH Q90710 999 4 -
SKPERKMVKGSGFH B3AT_HUMAN 690 4 -
SQKARRLLKGSGFH B3A3_HUMAN 1012 4 -
SQKARRLLKGSGFH B3A3_RAT 1007 4 -
SQKARRLLKGSGFH B3A3_MOUSE 1007 4 -
SKPERKMIKGSGFH B3AT_MOUSE 708 4 -
SKPERKMIKGSGFH B3AT_RAT 706 4 -
SQKARRLLKGSGFH O18917 1013 4 -
SKPERKMVKGSGFH B3AT_ONCMY 703 4 -
SKPERKMVKGSGFH Q91452 697 4 -
NRKEHKLKKGAGYH O15153 763 4 -
NRKEHKLKKGAGYH O35422 763 4 -
NRKEHKLKKGAGYH O54815 763 4 -
NRKEHKLKKGAGYH O97915 763 4 -
NRKEHKLQKGAGYH O88343 807 4 -
NRKEHKLKKGAGYH O13134 763 4 -
SKPERKLVKGSGFH Q90579 623 4 -
SKPERKLVKGSGFH B3AT_CHICK 701 4 -
NRKEHKLKKGAGYH O60350 725 4 -
NRKEHKLKKGCGYH O95233 809 4 -
NRKENKLKKGCGYH O61304 762 4 -
NRKENKLKKGCGYH Q20642 804 4 -