| Literature References | 1. MAYO, M.A., ROBINSON, D.J., JOLLY, C.A. AND HYMAN, L.
Nucleotide sequence of potato leafroll luteovirus RNA.
J.GEN.VIROL. 70 1037-1051 (1989).
2. VAN DER WILK, F., HUISMAN, M.J., CORNELISSEN, B.J., HUTTINGA, H.
AND GOLDBACH, R.
Nucleotide sequence and organization of potato leafroll virus genomic RNA.
FEBS LETT. 245 51-56 (1989).
3.VEIDT, I., LOT, H., LEISER, M., SCHEIDECKER, D., GUILLEY, H.,
RICHARDS, K. AND JONARD, G.
Nucleotide sequence of beet western yellows virus RNA.
NUCLEIC ACIDS RES. 16 9917-9932 (1988).
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| Documentation | The nucleotide sequence for the RNA of potato leafroll luteovirus (PLRV) has
been determined [1,2]. The sequence contains six large open reading frames
(ORFs). The 5' coding region encodes two polypeptides of 28K and 70K, which
overlap in different reading frames; it is suggested that the third ORF in
the 5' block is translated by frameshift readthrough near the end of the 70K
protein, yielding a 118K polypeptide [1]. Segments of the predicted amino
acid sequences of these ORFs resemble those of known viral RNA polymerases,
ATP-binding proteins and viral genome-linked proteins.
The nucleotide sequence of the genomic RNA of beet western yellow virus
(BWYV) has been determined [3]. The sequence contains six long ORFs. A
cluster of three of these ORFs, including the coat protein cistron, display
extensive amino acid sequence similarity to corresponding ORFs of a second
luteovirus, the PAV isolate of barley yellow dwarf virus (BYDV) [3].
LVIRUSORF2 is a 9-element fingerprint that provides a signature for the
luteovirus ORF2 putative replicase 1 family. The fingerprint was derived
from an initial alignment of 7 sequences: the motifs were drawn from short
conserved regions spanning the C-terminal half of the alignment. A single
iteration on OWL30.1 was required to reach convergence, no further
sequences being identified beyond the starting set. A single partial match
was found, JQ1383, a hypothetical protein from pea enation mosaic virus
that matches motifs 2 and 5.
An update on SPTR37_9f identified a true set of 7 sequences.
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