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PR00888

Identifier
SM22CALPONIN  [View Relations]  [View Alignment]  
Accession
PR00888
No. of Motifs
8
Creation Date
07-JUN-1998  (UPDATE 04-JUL-1999)
Title
Smooth muscle protein/calponin family signature
Database References
PRINTS; PR00889 CALPONIN; PR00890 TRANSGELIN
PROSITE; PS01052 CALPONIN
BLOCKS; BL01052
PFAM; PF00402 calponin
INTERPRO; IPR000557
Literature References
1. STRASSER, P., GIMONA, M., MOESSLER, H., HERZOG M. AND SMALL, J.V.
Mammalian calponin. Identification and expression of genetic variants.
FEBS LETT. 330 13-18 (1993). 
 
2. APPLEGATE, D., FENG, W., GREEN, R.S.and TAUBMAN, M.B.
Cloning and expression of a novel acidic calponin isoform from rat 
aortic vascular smooth muscle. 
J.BIOL.CHEM. 269 10683-10690 (1994). 
 
3. SAMAHA, F.F., IP, H.S., MORRISEY, E.E., SELTZER, J., TANG, Z., 
SOLWAY, J. AND PARMACEK, M.S.
Developmental pattern of expression and genomic organization of the 
calponin-h1 gene. a contractile smooth muscle cell marker. 
J.BIOL.CHEM. 271 395-403 (1996). 
 
4. SOLWAY, J., SELTZER, J., SAMAHA, F.F., KIM, S., ALGER, L.E., NIU, Q.,
MORRISEY, E.E., IP, H.S. AND PARMACEK, M.S.
Structure and expression of a smooth muscle cell-specific gene, SM22 alpha. 
J.BIOL.CHEM. 270 13460-13469 (1995). 
 
5. PRINJHA, R.K., SHAPLAND, C.E., HSUAN, J.J., TOTTY, N.F., MASON, I.J.
AND LAWSON, D.
Cloning and sequencing of cDNAs encoding the actin cross-linking protein
transgelin defines a new family of actin-associated proteins. 
CELL MOTIL.CYTOSKEL. 28 243-255 (1994). 

Documentation
Calponin is a smooth muscle-specific, actin-, tropomyosin- and calmodulin-
binding protein believed to be involved in regulation or modulation of 
contraction [1,2]; interaction of the protein with actin inhibits actomyosin 
MgATPase activity. Multiple isoforms are found in smooth muscle [2].
 
Calponin is a basic protein of ~34 Kd [3]. The protein contains three 
repeats of a well-conserved 26-residue domain, which is also found in a 
variety of proteins whose physiological role is as yet unclear (these 
include vertebrate smooth muscle protein (SM22 or transgelin), Drosophila
synchronous flight muscle protein, C.elegans unc-87 protein, and rat
neuronal protein NP25).
 
SM22-alpha is expressed exclusively in smooth muscle-containing tissues of
adult animals and is one of the earliest markers of differentiated smooth
muscle cells (SMCs) [4]. SM22-alpha mRNA is expressed at high levels in the aorta,
uterus, lung, and intestine, and in primary cultures of rat aortic SMCs,
and the SMC line, A7r5 [4].
 
Transgelin is the product of a single gene that is conserved in yeast,
Drosophila, molluscs and humans [5], and is highly similar to several other
proteins of unknown function (including mouse p27 and human WS3-10). The 
smaller domains of similarity shared between transgelin and other proteins, 
such as rat NP25, chicken calponins alpha and beta, and Drosophila mp20,
suggest that these proteins may be classified as members of a new transgelin
multigene family [5]. 
 
SM22CALPONIN is an 8-element fingerprint that provides a signature for
the calponin/SM22 family. The fingerprint was derived from an initial
alignment of 11 sequences: the motifs were drawn from conserved regions
spanning virtually the full alignment length - motif 8 lies in the
C-terminal calponin-like domain encoded by PROSITE pattern CALPONIN
(PS01052). Two iterations on OWL30.2 were required to reach convergence,
at which point a true set comprising 23 sequences was identified. Several
partial matches were also found, all of which are fragments and/or
SM22/calponin homologues that fail to match one or more motifs. 
 
An update on SPTR37_9f identified a true set of 17 sequences, and 8
partial matches.
Summary Information
  17 codes involving  8 elements
0 codes involving 7 elements
0 codes involving 6 elements
0 codes involving 5 elements
2 codes involving 4 elements
2 codes involving 3 elements
2 codes involving 2 elements
Composite Feature Index
81717171717171717
700000000
600000000
500000000
410222010
300012021
200202000
12345678
True Positives
CLP1_HUMAN    CLP1_MOUSE    CLP1_PIG      CLP1_RAT      
CLP2_MOUSE CLPA_RAT CLPO_CHICK NP25_RAT
O93547 Q15417 Q24799 Q92578
SM22_CHICK SM22_HUMAN SM22_MOUSE SM22_RAT
SM2H_HUMAN
True Positive Partials
Codes involving 4 elements
MP20_DROME O44788
Codes involving 3 elements
P91888 Q93713
Codes involving 2 elements
O44727 P91763
Sequence Titles
CLP1_HUMAN  CALPONIN H1, SMOOTH MUSCLE (BASIC CALPONIN) - HOMO SAPIENS (HUMAN). 
CLP1_MOUSE CALPONIN H1, SMOOTH MUSCLE (BASIC CALPONIN) - MUS MUSCULUS (MOUSE).
CLP1_PIG CALPONIN H1, SMOOTH MUSCLE (BASIC CALPONIN) - SUS SCROFA (PIG).
CLP1_RAT CALPONIN H1, SMOOTH MUSCLE (BASIC CALPONIN) - RATTUS NORVEGICUS (RAT).
CLP2_MOUSE CALPONIN H2, SMOOTH MUSCLE - MUS MUSCULUS (MOUSE).
CLPA_RAT CALPONIN, ACIDIC ISOFORM (CALPONIN, NON-MUSCLE ISOFORM) - RATTUS NORVEGICUS (RAT).
CLPO_CHICK CALPONIN ALPHA AND BETA, SMOOTH MUSCLE - GALLUS GALLUS (CHICKEN).
NP25_RAT NEURONAL PROTEIN NP25 - RATTUS NORVEGICUS (RAT).
O93547 CALPONIN H3 - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
Q15417 ACIDIC CALPONIN - HOMO SAPIENS (HUMAN).
Q24799 MYOPHILIN ANTIGEN - ECHINOCOCCUS GRANULOSUS.
Q92578 NEUTRAL CALPONIN - HOMO SAPIENS (HUMAN).
SM22_CHICK SMOOTH MUSCLE PROTEIN 22-ALPHA (SM22-ALPHA) - GALLUS GALLUS (CHICKEN).
SM22_HUMAN SMOOTH MUSCLE PROTEIN 22-ALPHA (SM22-ALPHA) (TRANSGELIN) (WS3-10) (22 KD ACTIN-BINDING PROTEIN) - HOMO SAPIENS (HUMAN).
SM22_MOUSE SMOOTH MUSCLE PROTEIN 22-ALPHA (SM22-ALPHA) (TRANSGELIN) (ACTIN- ASSOCIATED PROTEIN P27) - MUS MUSCULUS (MOUSE).
SM22_RAT SMOOTH MUSCLE PROTEIN 22-ALPHA (SM22-ALPHA) (TRANSGELIN) - RATTUS NORVEGICUS (RAT).
SM2H_HUMAN SM22-ALPHA HOMOLOG (HA1756) (KIAA0120) - HOMO SAPIENS (HUMAN).

MP20_DROME MUSCLE-SPECIFIC PROTEIN 20 - DROSOPHILA MELANOGASTER (FRUIT FLY).
O44788 D1069.2 PROTEIN - CAENORHABDITIS ELEGANS.

P91888 CALPONIN HOMOLOG - SCHISTOSOMA MANSONI (BLOOD FLUKE).
Q93713 F43G9.9 PROTEIN - CAENORHABDITIS ELEGANS.

O44727 F49D11.8 PROTEIN - CAENORHABDITIS ELEGANS.
P91763 CALPONIN HOMOLOG MJCAP-1 - MELOIDOGYNE JAVANICA (ROOT-KNOT NEMATODE).
Scan History
OWL30_2    2  100  NSINGLE    
SPTR37_9f 1 40 NSINGLE
Initial Motifs
Motif 1  width=15
Element Seqn Id St Int Rpt
NRGPAYGLSAEVKNK CLP1_HUMAN 7 7 -
NKGPSYGLSAEVKNK CLPA_RAT 5 5 -
NKGPSYGMSREVQSK SM22_HUMAN 2 2 -
NKGPSYGMSREVQSK SM22_MOUSE 2 2 -
NKGPSYGMSREVQSK SM22_RAT 2 2 -
NKGPAYGMSRDVQSK SM22_CHICK 2 2 -
NRGPSYGLSREVQEK NP25_RAT 3 3 -
NKGPSYGLSAEVKNR CLP2_HUMAN 7 7 -
NRGPAYGLSAEVKNK CLP1_MOUSE 7 7 -
NRGPAYGLSAEVKNK CLP1_RAT 7 7 -
NRGPAYGLSAEVKNK CLP1_PIG 7 7 -

Motif 2 width=14
Element Seqn Id St Int Rpt
YDHQREQELREWIE CLP1_HUMAN 26 4 -
YDEELEERLVEWII SM22_HUMAN 21 4 -
YDEELEERLVEWIV SM22_MOUSE 21 4 -
YDEELEERLVEWIV SM22_RAT 21 4 -
YDDELEDRLVEWIV SM22_CHICK 21 4 -
YDADLENKLVDWII NP25_RAT 22 4 -
YDPQKEAELRTWIE CLP2_HUMAN 26 4 -
YDHQREQELREWIE CLP1_MOUSE 26 4 -
YDHQREQELREWIE CLP1_RAT 26 4 -
YDHQQEQELREWIE CLP1_PIG 26 4 -
YDQQAEEDLRNWIE CLPA_RAT 24 4 -

Motif 3 width=16
Element Seqn Id St Int Rpt
FQLGLKDGIILCELIN CLPA_RAT 48 10 -
FQVWLKNGVILSKLVN SM22_MOUSE 51 16 -
FQRGLKDGTILCTLMN CLP2_HUMAN 50 10 -
FQKWLMDGTVLCKLIN NP25_RAT 52 16 -
FQVWLKNGIVLSQLVN SM22_CHICK 51 16 -
FQVWLKNGVILSKLVN SM22_RAT 51 16 -
FMDGLKDGIILCEFIN CLP1_MOUSE 50 10 -
FMDGLKDGIILCEFIN CLP1_RAT 50 10 -
FMDGLKDGIILCEFIN CLP1_PIG 50 10 -
FMDGLKDGIILCEFIN CLP1_HUMAN 50 10 -
FQVWLKNGVILSKLVN SM22_HUMAN 51 16 -

Motif 4 width=17
Element Seqn Id St Int Rpt
KQMEQVAQFLKAAEDYG SM22_MOUSE 88 21 -
HQLENLSNFIKAMVSYG CLP2_HUMAN 83 17 -
HQLENIGNFIKAITKYG CLP1_MOUSE 83 17 -
HQLENIGNFIKAITKYG CLP1_RAT 83 17 -
HQLENIGNFIKAITKYG CLP1_PIG 83 17 -
HQLENIGNFIKAITKYG CLP1_HUMAN 83 17 -
PQLENIGNFIKAIQAYG CLPA_RAT 81 17 -
KQMEQVAQFLKAAEDSG SM22_HUMAN 88 21 -
KQMEQVAQFLKAAEDYG SM22_RAT 88 21 -
KQMEQIAQFLKAAEDYG SM22_CHICK 88 21 -
KQMEQISQFLKAAEVYG NP25_RAT 88 20 -

Motif 5 width=16
Element Seqn Id St Int Rpt
GVTKTDMFQTVDLFEG SM22_RAT 104 -1 -
GMNPVDLFEANDLFES CLP2_HUMAN 99 -1 -
GVRTTDIFQTVDLWEG NP25_RAT 104 -1 -
GVVKTDMFQTVDLFEA SM22_CHICK 104 -1 -
GVKPHDIFEANDLFEN CLP1_MOUSE 99 -1 -
GVKPHDIFEANDLFEN CLP1_RAT 99 -1 -
GVKPHDIFEANDLFEN CLP1_PIG 99 -1 -
GVKPHDIFEANDLFEN CLP1_HUMAN 99 -1 -
GMKPHDIFEANDLFEN CLPA_RAT 97 -1 -
GVIKTDMFQTVDLFEG SM22_HUMAN 104 -1 -
GVIKTDMFQTVDLYEG SM22_MOUSE 104 -1 -

Motif 6 width=15
Element Seqn Id St Int Rpt
VQSTLLALASMAKTK CLP1_HUMAN 120 5 -
VQSTLLALASMAKTK CLP1_MOUSE 120 5 -
VQSTLLALASMAKTK CLP1_RAT 120 5 -
VQSTLLALASMAKTK CLP1_PIG 120 5 -
VQTTLVALAGLAKTK CLPA_RAT 118 5 -
VQRTLMALGSLAVTK SM22_HUMAN 125 5 -
VQRTLMALGSLAVTK SM22_MOUSE 125 5 -
VQRTVMALGSLAVTK SM22_RAT 125 5 -
VQRTLVALGSLAVTK SM22_CHICK 125 5 -
VQRTLMALGSVAVTK NP25_RAT 125 5 -
VQVSLLALAGKAKTK CLP2_HUMAN 120 5 -

Motif 7 width=14
Element Seqn Id St Int Rpt
FSEEQLRQGQNVIG NP25_RAT 162 22 -
FEPEKLREGRNIIG CLP1_MOUSE 152 17 -
FEPEKLREGRNIIG CLP1_RAT 152 17 -
FEPEKLREGRNIIG CLP1_PIG 152 17 -
FEPGKLREGRNIIG CLP1_HUMAN 152 17 -
FDDATMKAGQCGIG CLP2_HUMAN 154 19 -
FDEGKLKAGQSVIG CLPA_RAT 152 19 -
FTESQLQEGKHVIG SM22_HUMAN 162 22 -
FTDSQLQEGKHVIG SM22_MOUSE 162 22 -
FTDSQLQEGKHVIG SM22_RAT 162 22 -
FSESQLKEGKNIIG SM22_CHICK 162 22 -

Motif 8 width=16
Element Seqn Id St Int Rpt
GLQMGTNKFASQQGMT CLP1_HUMAN 165 -1 -
GLQMGSNRGASQAGMT SM22_HUMAN 175 -1 -
GLQMGSNKGASQAGMT NP25_RAT 175 -1 -
GLQMGTNKGASQAGMS SM22_CHICK 175 -1 -
GLQMGTNKFASQQGMT CLP1_MOUSE 165 -1 -
GLQMGTNKCASQSGMH CLP2_HUMAN 167 -1 -
GLQMGSNRGASQAGMT SM22_RAT 175 -1 -
GLQMGSNRGASQAGMT SM22_MOUSE 175 -1 -
GLQMGTNKFASQQGMT CLP1_RAT 165 -1 -
GLQMGTNKFASQQGMT CLP1_PIG 165 -1 -
GLQMGTNKCASQAGMT CLPA_RAT 165 -1 -
Final Motifs
Motif 1  width=15
Element Seqn Id St Int Rpt
NRGPAYGLSAEVKNK CLP1_MOUSE 7 7 -
NRGPAYGLSAEVKNK CLP1_RAT 7 7 -
NRGPAYGLSAEVKNK CLP1_PIG 7 7 -
NRGPAYGLSAEVKNK CLP1_HUMAN 7 7 -
NKGPSYGLSAEVKNK Q15417 5 5 -
NKGPSYGLSAEVKNK CLPA_RAT 5 5 -
NRGPAYGLSAEVKNK CLPO_CHICK 7 7 -
NKGPSYGMSREVQSK SM22_HUMAN 2 2 -
NKGPSYGMSREVQSK SM22_MOUSE 2 2 -
NKGPSYGMSREVQSK SM22_RAT 2 2 -
NKGPSYGLSAEVKNR CLP2_MOUSE 7 7 -
NKGPSYGLSAEVKNR Q92578 7 7 -
NKGPAYGMSRDVQSK SM22_CHICK 2 2 -
NRGPSYGLSREVQEK NP25_RAT 3 3 -
NRGPAYGLSREVQQK SM2H_HUMAN 3 3 -
NKGPSYGLSAEVKNK O93547 6 6 -
NVPPPSGLSYQVKKK Q24799 3 3 -

Motif 2 width=14
Element Seqn Id St Int Rpt
YDHQREQELREWIE CLP1_MOUSE 26 4 -
YDHQREQELREWIE CLP1_RAT 26 4 -
YDHQQEQELREWIE CLP1_PIG 26 4 -
YDHQREQELREWIE CLP1_HUMAN 26 4 -
YDHQAEEDLRNWIE Q15417 24 4 -
YDQQAEEDLRNWIE CLPA_RAT 24 4 -
YDPQTERQLRVWIE CLPO_CHICK 26 4 -
YDEELEERLVEWII SM22_HUMAN 21 4 -
YDEELEERLVEWIV SM22_MOUSE 21 4 -
YDEELEERLVEWIV SM22_RAT 21 4 -
YDPQKEAELRSWIE CLP2_MOUSE 26 4 -
YDPQKEAELRTWIE Q92578 26 4 -
YDDELEDRLVEWIV SM22_CHICK 21 4 -
YDADLENKLVDWII NP25_RAT 22 4 -
YDADLEQILIQWIT SM2H_HUMAN 22 4 -
YDPQKETELKVWIE O93547 25 4 -
RDKDQENEALEWIE Q24799 22 4 -

Motif 3 width=16
Element Seqn Id St Int Rpt
FMDGLKDGIILCEFIN CLP1_MOUSE 50 10 -
FMDGLKDGIILCEFIN CLP1_RAT 50 10 -
FMDGLKDGIILCEFIN CLP1_PIG 50 10 -
FMDGLKDGIILCEFIN CLP1_HUMAN 50 10 -
FQLGLKDGIILCELIN Q15417 48 10 -
FQLGLKDGIILCELIN CLPA_RAT 48 10 -
FMDGLKDGVILCELIN CLPO_CHICK 50 10 -
FQVWLKNGVILSKLVN SM22_HUMAN 51 16 -
FQVWLKNGVILSKLVN SM22_MOUSE 51 16 -
FQVWLKNGVILSKLVN SM22_RAT 51 16 -
FQKGLKDGVILCTLMN CLP2_MOUSE 50 10 -
FQKGLKDGTILCTLMN Q92578 50 10 -
FQVWLKNGIVLSQLVN SM22_CHICK 51 16 -
FQKWLMDGTVLCKLIN NP25_RAT 52 16 -
FQNWLKDGTVLCELIN SM2H_HUMAN 52 16 -
FQKGLKDGVILCELMN O93547 49 10 -
YEDILKDGTVLCKLMN Q24799 48 12 -

Motif 4 width=17
Element Seqn Id St Int Rpt
HQLENIGNFIKAITKYG CLP1_MOUSE 83 17 -
HQLENIGNFIKAITKYG CLP1_RAT 83 17 -
HQLENIGNFIKAITKYG CLP1_PIG 83 17 -
HQLENIGNFIKAITKYG CLP1_HUMAN 83 17 -
PQLENIGNFIKAIQAYG Q15417 81 17 -
PQLENIGNFIKAIQAYG CLPA_RAT 81 17 -
HKLENIGNFLRAIKHYG CLPO_CHICK 83 17 -
KQMEQVAQFLKAAEDSG SM22_HUMAN 88 21 -
KQMEQVAQFLKAAEDYG SM22_MOUSE 88 21 -
KQMEQVAQFLKAAEDYG SM22_RAT 88 21 -
HQLENLSNFIKAMVSYG CLP2_MOUSE 83 17 -
HQLENLSNFIKAMVSYG Q92578 83 17 -
KQMEQIAQFLKAAEDYG SM22_CHICK 88 21 -
KQMEQISQFLKAAEVYG NP25_RAT 88 20 -
KQMEQISQFLQAAERYG SM2H_HUMAN 88 20 -
HQLENLSNFIKAMSLYG O93547 82 17 -
KIMENISAFLEAMKGYG Q24799 82 18 -

Motif 5 width=16
Element Seqn Id St Int Rpt
GVKPHDIFEANDLFEN CLP1_MOUSE 99 -1 -
GVKPHDIFEANDLFEN CLP1_RAT 99 -1 -
GVKPHDIFEANDLFEN CLP1_PIG 99 -1 -
GVKPHDIFEANDLFEN CLP1_HUMAN 99 -1 -
GMKPHDIFEANDLFEN Q15417 97 -1 -
GMKPHDIFEANDLFEN CLPA_RAT 97 -1 -
GVKPHDIFEANDLFEN CLPO_CHICK 99 -1 -
GVIKTDMFQTVDLFEG SM22_HUMAN 104 -1 -
GVIKTDMFQTVDLYEG SM22_MOUSE 104 -1 -
GVTKTDMFQTVDLFEG SM22_RAT 104 -1 -
GMNPVDLFEANDLFES CLP2_MOUSE 99 -1 -
GMNPVDLFEANDLFES Q92578 99 -1 -
GVVKTDMFQTVDLFEA SM22_CHICK 104 -1 -
GVRTTDIFQTVDLWEG NP25_RAT 104 -1 -
GINTTDIFQTVDLWEG SM2H_HUMAN 104 -1 -
GMKSVDLFEANDLFEN O93547 98 -1 -
GVPVADLFQTVDLFEK Q24799 98 -1 -

Motif 6 width=15
Element Seqn Id St Int Rpt
VQSTLLALASMAKTK CLP1_MOUSE 120 5 -
VQSTLLALASMAKTK CLP1_RAT 120 5 -
VQSTLLALASMAKTK CLP1_PIG 120 5 -
VQSTLLALASMAKTK CLP1_HUMAN 120 5 -
VQTTLVALAGLAKTK Q15417 118 5 -
VQTTLVALAGLAKTK CLPA_RAT 118 5 -
VQSTLIALASQAKTK CLPO_CHICK 120 5 -
VQRTLMALGSLAVTK SM22_HUMAN 125 5 -
VQRTLMALGSLAVTK SM22_MOUSE 125 5 -
VQRTVMALGSLAVTK SM22_RAT 125 5 -
VQVSLLALAGKAKTK CLP2_MOUSE 120 5 -
VQVSLLALAGKAKTK Q92578 120 5 -
VQRTLVALGSLAVTK SM22_CHICK 125 5 -
VQRTLMALGSVAVTK NP25_RAT 125 5 -
VQRTLMNLGGLAVAR SM2H_HUMAN 125 5 -
VQVSLLSLAGLAKSK O93547 119 5 -
VTRTLFALGRTCQTH Q24799 119 5 -

Motif 7 width=14
Element Seqn Id St Int Rpt
FEPEKLREGRNIIG CLP1_MOUSE 152 17 -
FEPEKLREGRNIIG CLP1_RAT 152 17 -
FEPEKLREGRNIIG CLP1_PIG 152 17 -
FEPGKLREGRNIIG CLP1_HUMAN 152 17 -
FDEGKLKAGQSVIG Q15417 152 19 -
FDEGKLKAGQSVIG CLPA_RAT 152 19 -
FQPEKLREGRNIIG CLPO_CHICK 152 17 -
FTESQLQEGKHVIG SM22_HUMAN 162 22 -
FTDSQLQEGKHVIG SM22_MOUSE 162 22 -
FTDSQLQEGKHVIG SM22_RAT 162 22 -
FDDATMKAGQCVIG CLP2_MOUSE 154 19 -
FDDATMKAGQCVIG Q92578 154 19 -
FSESQLKEGKNIIG SM22_CHICK 162 22 -
FSEEQLRQGQNVIG NP25_RAT 162 22 -
FSDNQLQEGKNVIG SM2H_HUMAN 162 22 -
FDDNTKKAGNCVIG O93547 152 18 -
FTEQQLREGQNVVS Q24799 153 19 -

Motif 8 width=16
Element Seqn Id St Int Rpt
GLQMGTNKFASQQGMT CLP1_MOUSE 165 -1 -
GLQMGTNKFASQQGMT CLP1_RAT 165 -1 -
GLQMGTNKFASQQGMT CLP1_PIG 165 -1 -
GLQMGTNKFASQQGMT CLP1_HUMAN 165 -1 -
GLQMGTNKCASQAGMT Q15417 165 -1 -
GLQMGTNKCASQAGMT CLPA_RAT 165 -1 -
GLQMGTNKFASQQGMT CLPO_CHICK 165 -1 -
GLQMGSNRGASQAGMT SM22_HUMAN 175 -1 -
GLQMGSNRGASQAGMT SM22_MOUSE 175 -1 -
GLQMGSNRGASQAGMT SM22_RAT 175 -1 -
GLQMGTNKCASQSGMT CLP2_MOUSE 167 -1 -
GLQMGTNKCASQSGMT Q92578 167 -1 -
GLQMGTNKGASQAGMS SM22_CHICK 175 -1 -
GLQMGSNKGASQAGMT NP25_RAT 175 -1 -
GLQMGTNRGASQAGMT SM2H_HUMAN 175 -1 -
SLQMGSNKGASQVGMT O93547 206 40 -
SLQYGSNKGASQAGIN Q24799 166 -1 -