SPRINT Home UMBER Home Contents Standard Search Advanced Search Relation Search

==SPRINT==> PRINTS View



  selected as


PR00868

Identifier
DNAPOLI  [View Relations]  [View Alignment]  
Accession
PR00868
No. of Motifs
9
Creation Date
29-JUN-1998  (UPDATE 10-JUN-1999)
Title
DNA-polymerase family A (pol I) signature
Database References
PRINTS; PR90005 DNADNAPOL
PROSITE; PS00447 DNA_POLYMERASE_A
BLOCKS; BL00447
PFAM; PF00476 DNA_pol_A
INTERPRO; IPR002298
PDB; 1KFS; 1KRP
SCOP; 1KFS; 1KRP
CATH; 1KFS; 1KRP
Literature References
1. JUNG, G., LEAVITT, M.C.,	HSIEH, J-C. AND	ITO, J.
Bacteriophage PRD1 DNA polymerase: Evolution of DNA	polymerases.
PROC.NATL.ACAD.SCI.U.S.A. 84 8287-8291	(1987).
 
2. DELARUE,	M., POCH, O., TORDO, N., MORAS,	D. AND ARGOS, P.
An attempt to unify	the structure of polymerases.
PROTEIN ENG. 3(6) 461-467 (1990).

Documentation
DNA	carries the biological information that instructs cells how to exist
in an ordered fashion: accurate replication is thus one of the most
important events in the cell life cycle. This function is mediated by
DNA-directed DNA-polymerases, which add nucleotide triphosphate (dNTP)
residues to the 5'-end of the growing DNA chain, using a complementary 
DNA as template. Small RNA molecules are generally used as primers for
chain elongation, although terminal proteins may also be used.
 
DNA-dependent DNA-polymerases have been grouped into families, denoted A, B
and X, on the basis of sequence similarities [1,2].	Members of family A, 
which includes bacterial and bacteriophage polymerases, share significant
similarity to E.coli polymerase I; hence family A is also known as the pol I
family. The	bacterial polymerases also contain an exonuclease activity,
which is coded for in the N-terminal portion. 
 
Three motifs, A, B and C, as defined by Delarue et al. [2], are seen to be 
conserved across all DNA-polymerases, with motifs A and C also seen in RNA- 
polymerases. They are centered on invariant residues, and their structural 
significance was implied from the Klenlow (E.coli) structure: motif A 
contains a strictly-conserved aspartate at the junction of a beta-strand 
and an alpha-helix; motif B contains an alpha-helix with positive charges; 
and motif C has a doublet of negative charges, located in a beta-turn-beta 
secondary structure [2]. 
 
DNAPOLI is a 9-element fingerprint that provides a signature for the DNA-
polymerase A family. The fingerprint was derived from an initial alignment
of 14 sequences: the motifs were drawn from conserved regions in the
C-terminal portion of the alignment - motif 1 spans strands 7 and 8, and
helix 16, and contains a conserved Arg, which binds a metal ion; motif 2 
straddles helix 17; motif 3 spans strand 9 and helix 19; motif 4 encompasses
"motif A", which contains one of the active site Asps; motif 5 spans the 
region encoded by PROSITE pattern DNA_POLYMERASE_A (PS00447), corresponding
to "motif B", which contains the strictly conserved active site Lys and the
conserved Tyr residue; motif 6 spans the C-terminal section of helix 24 and
the start of helix 25; motif 7 straddles strands 10 and 11; motif 8 spans
the central portion of helix 26; and motif 9 includes "motif C", which 
contains an active site Asp. Two iterations on OWL30.1 were required to 
reach convergence, at which point a true set comprising 28 sequences was
identified. Several partial matches were also found, all of which are true
but distant family members, including two yeast gamma polymerases. 
 
An update on SPTR37_9f identified a true set of 26 sequences, and 15
partial matches.
Summary Information
  26 codes involving  9 elements
0 codes involving 8 elements
0 codes involving 7 elements
3 codes involving 6 elements
2 codes involving 5 elements
3 codes involving 4 elements
4 codes involving 3 elements
3 codes involving 2 elements
Composite Feature Index
9262626262626262626
8000000000
7000000000
6303130233
5002021122
4102231021
3304040010
2000120012
123456789
True Positives
DPO1_ANATH    DPO1_BACCA    DPO1_BACST    DPO1_BACSU    
DPO1_CHLAU DPO1_DEIRA DPO1_ECOLI DPO1_HAEIN
DPO1_HELPY DPO1_LACLC DPO1_MYCLE DPO1_MYCTU
DPO1_RICPR DPO1_STRPN DPO1_THEAQ DPO1_THECA
DPO1_THEFI DPO1_THEFL DPO1_THETH DPO1_TREPA
DPOL_BPSP1 O24675 O51498 O84500
Q45458 Q55971
True Positive Partials
Codes involving 6 elements
DPO1_AQUAE O18475 O75417
Codes involving 5 elements
O65531 Q23133
Codes involving 4 elements
DPOL_BPMD2 DPOL_BPT5 Q38032
Codes involving 3 elements
DPOL_BPML5 DPOL_BPT3 DPOL_BPT7 Q38544
Codes involving 2 elements
DPOG_PICPA DPOG_SCHPO DPOG_YEAST
Sequence Titles
DPO1_ANATH  DNA POLYMERASE I (EC 2.7.7.7) (POL I) - ANAEROCELLUM THERMOPHILUM. 
DPO1_BACCA DNA POLYMERASE I (EC 2.7.7.7) (POL I) - BACILLUS CALDOTENAX.
DPO1_BACST DNA POLYMERASE I (EC 2.7.7.7) (POL I) - BACILLUS STEAROTHERMOPHILUS.
DPO1_BACSU DNA POLYMERASE I (EC 2.7.7.7) (POL I) - BACILLUS SUBTILIS.
DPO1_CHLAU DNA POLYMERASE I (EC 2.7.7.7) (POL I) - CHLOROFLEXUS AURANTIACUS.
DPO1_DEIRA DNA POLYMERASE I (EC 2.7.7.7) (POL I) - DEINOCOCCUS RADIODURANS.
DPO1_ECOLI DNA POLYMERASE I (EC 2.7.7.7) (POL I) - ESCHERICHIA COLI.
DPO1_HAEIN DNA POLYMERASE I (EC 2.7.7.7) (POL I) - HAEMOPHILUS INFLUENZAE.
DPO1_HELPY DNA POLYMERASE I (EC 2.7.7.7) (POL I) - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).
DPO1_LACLC DNA POLYMERASE I (EC 2.7.7.7) (POL I) - LACTOCOCCUS LACTIS (SUBSP. CREMORIS) (STREPTOCOCCUS CREMORIS).
DPO1_MYCLE DNA POLYMERASE I (EC 2.7.7.7) (POL I) - MYCOBACTERIUM LEPRAE.
DPO1_MYCTU DNA POLYMERASE I (EC 2.7.7.7) (POL I) - MYCOBACTERIUM TUBERCULOSIS.
DPO1_RICPR DNA POLYMERASE I (EC 2.7.7.7) (POL I) - RICKETTSIA PROWAZEKII.
DPO1_STRPN DNA POLYMERASE I (EC 2.7.7.7) (POL I) - STREPTOCOCCUS PNEUMONIAE.
DPO1_THEAQ DNA POLYMERASE I, THERMOSTABLE (EC 2.7.7.7) (TAQ POLYMERASE 1) - THERMUS AQUATICUS.
DPO1_THECA DNA POLYMERASE I, THERMOSTABLE (EC 2.7.7.7) (TAC POLYMERASE 1) - THERMUS AQUATICUS (SUBSP. CALDOPHILUS).
DPO1_THEFI DNA POLYMERASE I, THERMOSTABLE (EC 2.7.7.7) (TFI POLYMERASE 1) - THERMUS FILIFORMIS.
DPO1_THEFL DNA POLYMERASE I, THERMOSTABLE (EC 2.7.7.7) (TFL POLYMERASE 1) - THERMUS AQUATICUS (SUBSP. FLAVUS).
DPO1_THETH DNA POLYMERASE I, THERMOSTABLE (EC 2.7.7.7) (TTH POLYMERASE 1) - THERMUS AQUATICUS (SUBSP. THERMOPHILUS).
DPO1_TREPA DNA POLYMERASE I (EC 2.7.7.7) (POL I) - TREPONEMA PALLIDUM.
DPOL_BPSP1 DNA POLYMERASE (EC 2.7.7.7) - BACTERIOPHAGE SP01.
O24675 DNA POLYMERASE I - BACILLUS STEAROTHERMOPHILUS.
O51498 DNA POLYMERASE I (POLA) - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
O84500 DNA POLYMERASE I - CHLAMYDIA TRACHOMATIS.
Q45458 DNA POLYMERASE I - BACILLUS STEAROTHERMOPHILUS.
Q55971 DNA POLYMERASE I - SYNECHOCYSTIS SP. (STRAIN PCC 6803).

DPO1_AQUAE DNA POLYMERASE I (EC 2.7.7.7) (POL I) - AQUIFEX AEOLICUS.
O18475 MUS308 - DROSOPHILA MELANOGASTER (FRUIT FLY).
O75417 DNA POLYMERASE ETA (EC 2.7.7.7) - HOMO SAPIENS (HUMAN).

O65531 HYPOTHETICAL 172.0 KD PROTEIN - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
Q23133 W03A3.2 PROTEIN - CAENORHABDITIS ELEGANS.

DPOL_BPMD2 DNA POLYMERASE (EC 2.7.7.7) - MYCOBACTERIOPHAGE D29.
DPOL_BPT5 DNA POLYMERASE (EC 2.7.7.7) - BACTERIOPHAGE T5.
Q38032 ORF 11 - BACTERIOPHAGE PHI-C31.

DPOL_BPML5 DNA POLYMERASE (EC 2.7.7.7) - MYCOBACTERIOPHAGE L5.
DPOL_BPT3 DNA POLYMERASE (EC 2.7.7.7) - BACTERIOPHAGE T3.
DPOL_BPT7 DNA POLYMERASE (EC 2.7.7.7) (T7 DNA POLYMERASE) - BACTERIOPHAGE T7.
Q38544 5B - BACTERIOPHAGE T3.

DPOG_PICPA DNA POLYMERASE GAMMA (EC 2.7.7.7) (MITOCHONDRIAL DNA POLYMERASE CATALYTIC SUBUNIT) - PICHIA PASTORIS (YEAST).
DPOG_SCHPO DNA POLYMERASE GAMMA (EC 2.7.7.7) (MITOCHONDRIAL DNA POLYMERASE CATALYTIC SUBUNIT) - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
DPOG_YEAST DNA POLYMERASE GAMMA (EC 2.7.7.7) (MITOCHONDRIAL DNA POLYMERASE CATALYTIC SUBUNIT) - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
Scan History
OWL30_1    2  100  NSINGLE    
SPTR37_9f 2 115 NSINGLE
Initial Motifs
Motif 1  width=23
Element Seqn Id St Int Rpt
LHTRFNQTATATGRLSSSDPNLQ DPO1_THEAQ 560 560 -
LHTRFNQTATATGRLSSSDPNLQ DPO1_THETH 562 562 -
VHTIFNQALTQTGRLSSTEPNLQ DPO1_BACCA 603 603 -
VHPSYNIHGTVTGRLSSNEPNAQ DPOL_BPSP1 577 577 -
IHTTFNQTIATTGRLSSTEPNLQ DPO1_MYCLE 633 633 -
IHTTFNQTIAATGRLSSTEPNLQ DPO1_MYCTU 629 629 -
IHTTFLQTSTTTGRLSSQEPNLQ RPFTSY1 596 596 -
IHTTFIQTGTATGRLSSHSPNLQ DPO1_HELPY 621 621 -
IHTDFNQAVTSTGRLSSSNPNLQ S77056 699 699 -
VHTSYHQAVTATGRLSSSDPNLQ DPO1_HAEIN 658 658 -
LHTTFAQTAVATGRLSSLNPNLQ DPO1_DEIRA 650 650 -
VHTSYHQAVTATGRLSSTDPNLQ DPO1_ECOLI 655 655 -
IHTRYVQDLTQTGRLSSVDPNLQ DPO1_STRPN 602 602 -
LHTRFNQTATATGRLSSSDPNLQ DPO1_THEFL 559 559 -

Motif 2 width=16
Element Seqn Id St Int Rpt
NTPTLFQYNFEIKKMF DPOL_BPSP1 606 6 -
NVPIRSSDGNKIREAF RPFTSY1 619 0 -
NIPIRSDFSRQIRRAF S77056 722 0 -
NIPIRLEEGRKIRQAF DPO1_BACCA 626 0 -
NIPVRTPLGQRIRRAF DPO1_THETH 585 0 -
NIPVRTPLGQRIRRAF DPO1_THEAQ 583 0 -
NIPVRTPLGQRIRRAF DPO1_THEFL 582 0 -
NIPARLEQGRLIRKAF DPO1_STRPN 625 0 -
NIPVRNEEGRRIRQAF DPO1_ECOLI 678 0 -
NIPIRSELGREIRKGF DPO1_DEIRA 673 0 -
NIPIRNEEGRHIRQAF DPO1_HAEIN 681 0 -
NIPIRTDAGRRIRDAF DPO1_MYCTU 652 0 -
NIPIRTNAGRQIRDAF DPO1_MYCLE 656 0 -
NIPVRSPKGLLIRKGF DPO1_HELPY 644 0 -

Motif 3 width=24
Element Seqn Id St Int Rpt
LLVALDYSQIELRVLAHLSGDENL DPO1_THEAQ 605 6 -
ALVALDYSQIELRVLAHLSGDENL DPO1_THETH 607 6 -
LIFAADYSQIELRVLAHIAEDDNL DPO1_BACCA 649 7 -
VLVVLDYSQIELRVLAHLSGDENL DPO1_THEFL 604 6 -
VLLSSDYSQIELRVLAHISKDEHL DPO1_STRPN 648 7 -
VIVSADYSQIELRIMAHLSRDKGL DPO1_ECOLI 700 6 -
TLIAADYSQIELRLLAHIADDPLM DPO1_DEIRA 695 6 -
SIVAADYSQIELRIMAHLSGDQGL DPO1_HAEIN 703 6 -
ELMTADYSQIEMRIMAHLSGDEGL DPO1_MYCTU 675 7 -
ELMTADYSQIEMRIMAHLSRDEGL DPO1_MYCLE 682 10 -
CLLGVDYSQIELRLLAHFSQDKDL DPO1_HELPY 667 7 -
VIVQFDYSQLELRILVCYYSRPYT DPOL_BPSP1 630 8 -
KLISADYSQIELRILSHIANIDVL RPFTSY1 641 6 -
LLVSADYSQIELRILAHLSQEPVL S77056 744 6 -

Motif 4 width=14
Element Seqn Id St Int Rpt
GEDLHSFVASRAFG DPO1_MYCLE 712 6 -
RQDVHGVTAKLLFG S77056 774 6 -
KEDIHTQTACQIFN RPFTSY1 671 6 -
DLDIHTKTAMDIFQ DPO1_BACCA 679 6 -
GKDIHTQTASWMFG DPO1_THETH 637 6 -
GRDIHTETASWMFG DPO1_THEAQ 635 6 -
GRDIHTQTASWMFG DPO1_THEFL 634 6 -
GADIHTSTAMRVFG DPO1_STRPN 678 6 -
GKDIHRATAAEVFG DPO1_ECOLI 730 6 -
GADIHRRTAAQVLG DPO1_DEIRA 725 6 -
GKDIHRSTAAEIFG DPO1_HAEIN 733 6 -
GEDLHSFVASRAFG DPO1_MYCTU 705 6 -
GRDIHLETSKALFG DPO1_HELPY 697 6 -
GADLHKAVASDAFG DPOL_BPSP1 660 6 -

Motif 5 width=26
Element Seqn Id St Int Rpt
RRNAKAVNFGVVYGISDFGLSNNLGI DPO1_STRPN 703 11 -
RRSAKAINFGLIYGMSAFGLARQLNI DPO1_ECOLI 754 10 -
RRAAKTVNFGVLYGMSAHRLSNDLGI DPO1_DEIRA 749 10 -
RRNAKAINFGLIYGMSAFGLSRQLGI DPO1_HAEIN 757 10 -
RRRVKAMSYGLAYGLSAYGLSQQLKI DPO1_MYCTU 729 10 -
RRRVKAMSYGLAYGLSAYGLATQLKI DPO1_MYCLE 736 10 -
RSIAKSINFGLVYGMGSKKLSETLNI DPO1_HELPY 718 7 -
RTASKKIQFGIVYQESARGLSEDLRA DPOL_BPSP1 684 10 -
RRKAKAINFGIIYGISAFGLAKQLNV RPFTSY1 695 10 -
RNLGKTINFGVIYGMGAQRFARETGI S77056 796 8 -
RRQAKAVNFGIVYGISDYGLAQNLNI DPO1_BACCA 703 10 -
RRAAKTVNFGVLYGMSAHRLSQELAI DPO1_THETH 661 10 -
RRAAKTINFGVLYGMSAHRLSQELAI DPO1_THEAQ 659 10 -
RRAAKTINFGVLYGMSAHRLSGELSI DPO1_THEFL 658 10 -

Motif 6 width=12
Element Seqn Id St Int Rpt
YFERYPGVLEYM DPO1_ECOLI 791 11 -
YFQRYPSVQQFM DPO1_HAEIN 794 11 -
YFARFGGVRDYL DPO1_MYCTU 766 11 -
YFARFGGVRDYL DPO1_MYCLE 773 11 -
YFKRFPSIKDYL DPO1_HELPY 755 11 -
YFKRFPKVSKWI DPOL_BPSP1 726 16 -
YFAEYKGVQEYM RPFTSY1 732 11 -
YHRTYAQVFDYL S77056 833 11 -
YFESFPGVKRYM DPO1_BACCA 740 11 -
YFQSFPKVRAWI DPO1_THETH 698 11 -
YFQSFPKVRAWI DPO1_THEAQ 696 11 -
YFQSYPKVRAWI DPO1_THEFL 695 11 -
YFERFPGIKNYM DPO1_STRPN 740 11 -
YFATYPGIRRYI DPO1_DEIRA 786 11 -

Motif 7 width=12
Element Seqn Id St Int Rpt
GYVETLFGRRLY DPO1_HAEIN 816 10 -
GYVTTIVGRRRY S77056 855 10 -
GYVTNFFGRKCF RPFTSY1 754 10 -
STVKTLTGATRN DPOL_BPSP1 748 10 -
SKAFTLLGRYRV DPO1_HELPY 777 10 -
GYTSTVLGRRRY DPO1_MYCLE 795 10 -
GYVTTLLHRRRY DPO1_BACCA 762 10 -
GYVETLFGRRRY DPO1_THETH 720 10 -
GYVETLFGRRRY DPO1_THEAQ 718 10 -
GYVETLFGRRRY DPO1_THEFL 717 10 -
GYVETLFKRRRE DPO1_STRPN 762 10 -
GYVETLDGRRLY DPO1_ECOLI 813 10 -
GYVETLYGRRRY DPO1_DEIRA 808 10 -
GYTSTVLGRRRY DPO1_MYCTU 788 10 -

Motif 8 width=17
Element Seqn Id St Int Rpt
NAPMQGTAADIIKRAMI DPO1_HAEIN 848 20 -
NTPIQGSAADIIKKAMI DPO1_BACCA 794 20 -
NMPVQGTAADLMKLAMV DPO1_THETH 752 20 -
NMPVQGTAADLMKLAMV DPO1_THEAQ 750 20 -
NMPVQGTAADLMKLAMV DPO1_THEFL 749 20 -
NSPIQGSAADILKIAMI DPO1_STRPN 794 20 -
NAPMQGTAADIIKRAMI DPO1_ECOLI 845 20 -
NMPIQGTAADIMKLAMV DPO1_DEIRA 840 20 -
NAPIQGSAADIIKVAMI DPO1_MYCTU 820 20 -
NAPIQGSAADIIKVAMI DPO1_MYCLE 827 20 -
NAIFQGSASDLLKLGML DPO1_HELPY 808 19 -
NTPIQGTGSDCTLMSLI DPOL_BPSP1 780 20 -
NAPIQGTNADIIKIAMI RPFTSY1 784 18 -
NAPIQGSSADIIKIAMV S77056 905 38 -

Motif 9 width=14
Element Seqn Id St Int Rpt
RMIMQVHDELVFEV DPO1_ECOLI 875 13 -
RICITVHDSIVLDC DPOL_BPSP1 810 13 -
RLLLQVHDELIFEI DPO1_HELPY 837 12 -
RMLLQVHDELLFEV DPO1_MYCLE 857 13 -
KMLLQVHDEIVLEV DPO1_STRPN 824 13 -
RLLLQVHDELILEA DPO1_BACCA 824 13 -
RLILQIHDELLFEV RPFTSY1 814 13 -
RMLLQVHDELIFEM S77056 933 11 -
RMLLQVHDELLLEA DPO1_THETH 780 11 -
RMLLQVHDELVLEA DPO1_THEAQ 778 11 -
RMLLQVHDELLFEI DPO1_MYCTU 850 13 -
RMLLQVHDELVLEA DPO1_THEFL 777 11 -
EMIMQVHDELVFEV DPO1_HAEIN 877 12 -
RMLLQVHDELLIEA DPO1_DEIRA 868 11 -
Final Motifs
Motif 1  width=23
Element Seqn Id St Int Rpt
VHTMFNQALTQTGRLSSVEPNLQ DPO1_BACST 602 602 -
VHTMFNQTLTQTGRLSSAEPNLQ O24675 604 604 -
VHTMFNQALTQTGRLSSAEPNLQ Q45458 602 602 -
VHTIFNQALTQTGRLSSTEPNLQ DPO1_BACCA 603 603 -
LHTRFNQTATATGRLSSSDPNLQ DPO1_THECA 562 562 -
LHTRFNQTATATGRLSSSDPNLQ DPO1_THETH 562 562 -
LHTRFNQTATATGRLSSSDPNLQ DPO1_THEAQ 560 560 -
LHTRFNQTATATGRLSSSDPNLQ DPO1_THEFI 560 560 -
LHTRFNQTATATGRLSSSDPNLQ DPO1_THEFL 559 559 -
VHTRFNQALTQTGRLSSTDPNLQ DPO1_BACSU 606 606 -
IHTRYVQDLTQTGRLSSVDPNLQ DPO1_STRPN 602 602 -
VHTSYHQAVTATGRLSSTDPNLQ DPO1_ECOLI 655 655 -
IHTSYNQLGAATGRLSSNNPNLQ DPO1_CHLAU 664 664 -
LHTTFAQTAVATGRLSSLNPNLQ DPO1_DEIRA 650 650 -
IHTRYVQDLTQTGRLSSVDPNLQ DPO1_LACLC 603 603 -
VHTSYHQAVTATGRLSSSDPNLQ DPO1_HAEIN 658 658 -
IHTTFNQTIAATGRLSSTEPNLQ DPO1_MYCTU 629 629 -
IHTTFNQTIATTGRLSSTEPNLQ DPO1_MYCLE 633 633 -
VHTSFVQIGTATGRLSSRNPNLQ DPO1_TREPA 724 724 -
VHTTFIQTGTATGRLASSDPNLQ DPO1_ANATH 577 577 -
LHTSFIQTKTATGRITSINPNLQ O51498 635 635 -
IHTTFLQTSTTTGRLSSQEPNLQ DPO1_RICPR 596 596 -
IHTDFNQAVTSTGRLSSSNPNLQ Q55971 699 699 -
IHPTFNQVGTVTGRLSCQDPNLQ O84500 594 594 -
IHTTFIQTGTATGRLSSHSPNLQ DPO1_HELPY 621 621 -
VHPSYNIHGTVTGRLSSNEPNAQ DPOL_BPSP1 577 577 -

Motif 2 width=16
Element Seqn Id St Int Rpt
NIPIRLEEGRKIRQAF DPO1_BACST 625 0 -
NIPIRLEEGRKIRQAF O24675 627 0 -
NIPIRLEEGRKIRQAF Q45458 625 0 -
NIPIRLEEGRKIRQAF DPO1_BACCA 626 0 -
NIPVRTPLGQRIRRAF DPO1_THECA 585 0 -
NIPVRTPLGQRIRRAF DPO1_THETH 585 0 -
NIPVRTPLGQRIRRAF DPO1_THEAQ 583 0 -
NIPVRTPLGQRIRKAF DPO1_THEFI 583 0 -
NIPVRTPLGQRIRRAF DPO1_THEFL 582 0 -
NIPIRLEEGRKIRQAF DPO1_BACSU 629 0 -
NIPARLEQGRLIRKAF DPO1_STRPN 625 0 -
NIPVRNEEGRRIRQAF DPO1_ECOLI 678 0 -
NIPVRTEEGREIRRAF DPO1_CHLAU 687 0 -
NIPIRSELGREIRKGF DPO1_DEIRA 673 0 -
NIPVRLEEGRKIRKAF DPO1_LACLC 626 0 -
NIPIRNEEGRHIRQAF DPO1_HAEIN 681 0 -
NIPIRTDAGRRIRDAF DPO1_MYCTU 652 0 -
NIPIRTNAGRQIRDAF DPO1_MYCLE 656 0 -
NIPIKSTEGRKIRQAF DPO1_TREPA 747 0 -
NIPVKYDEGKLIRKVF DPO1_ANATH 600 0 -
NIPIKDEKGRKIRKAF O51498 658 0 -
NVPIRSSDGNKIREAF DPO1_RICPR 619 0 -
NIPIRSDFSRQIRRAF Q55971 722 0 -
NIPVRSERGRSLREAF O84500 617 0 -
NIPVRSPKGLLIRKGF DPO1_HELPY 644 0 -
NTPTLFQYNFEIKKMF DPOL_BPSP1 606 6 -

Motif 3 width=24
Element Seqn Id St Int Rpt
LIFAADYSQIELRVLAHIAEDDNL DPO1_BACST 648 7 -
LIFAADYSQIELRVLAHIADDDNL O24675 650 7 -
LIFAADYSQIELRVLAHIADDDNL Q45458 648 7 -
LIFAADYSQIELRVLAHIAEDDNL DPO1_BACCA 649 7 -
ALVALDYSQIELRVLAHLSGDENL DPO1_THECA 607 6 -
ALVALDYSQIELRVLAHLSGDENL DPO1_THETH 607 6 -
LLVALDYSQIELRVLAHLSGDENL DPO1_THEAQ 605 6 -
LLLAADYSQIELRVLAHLSGDENL DPO1_THEFI 605 6 -
VLVVLDYSQIELRVLAHLSGDENL DPO1_THEFL 604 6 -
LIFAADYSQIELRVLAHISKDENL DPO1_BACSU 652 7 -
VLLSSDYSQIELRVLAHISKDEHL DPO1_STRPN 648 7 -
VIVSADYSQIELRIMAHLSRDKGL DPO1_ECOLI 700 6 -
RFVAADYSQIELRVLAHMSGDENL DPO1_CHLAU 709 6 -
TLIAADYSQIELRLLAHIADDPLM DPO1_DEIRA 695 6 -
LLLSSDYSQIELRVLAHISADEHL DPO1_LACLC 648 6 -
SIVAADYSQIELRIMAHLSGDQGL DPO1_HAEIN 703 6 -
ELMTADYSQIEMRIMAHLSGDEGL DPO1_MYCTU 675 7 -
ELMTADYSQIEMRIMAHLSRDEGL DPO1_MYCLE 682 10 -
ELISADYTQIELVVLAHLSQDRNL DPO1_TREPA 769 6 -
VLIDADYSQIELRILAHISEDERL DPO1_ANATH 622 6 -
IFISADYSQIELAILAHLSQDEVL O51498 680 6 -
KLISADYSQIELRILSHIANIDVL DPO1_RICPR 641 6 -
LLVSADYSQIELRILAHLSQEPVL Q55971 744 6 -
YFLAADYSQIELRFLAHLSQDEML O84500 640 7 -
CLLGVDYSQIELRLLAHFSQDKDL DPO1_HELPY 667 7 -
VIVQFDYSQLELRILVCYYSRPYT DPOL_BPSP1 630 8 -

Motif 4 width=14
Element Seqn Id St Int Rpt
GLDIHTKTAMDIFH DPO1_BACST 678 6 -
DLDIHTKTAMDIFH O24675 680 6 -
DLDIHTKTAMDIFH Q45458 678 6 -
DLDIHTKTAMDIFQ DPO1_BACCA 679 6 -
GKDIHTQTASWMFG DPO1_THECA 637 6 -
GKDIHTQTASWMFG DPO1_THETH 637 6 -
GRDIHTETASWMFG DPO1_THEAQ 635 6 -
GKDIHTETAAWMFG DPO1_THEFI 635 6 -
GRDIHTQTASWMFG DPO1_THEFL 634 6 -
DMDIHTKTAMDVFH DPO1_BACSU 682 6 -
GADIHTSTAMRVFG DPO1_STRPN 678 6 -
GKDIHRATAAEVFG DPO1_ECOLI 730 6 -
GLDIHAATASRLFG DPO1_CHLAU 739 6 -
GADIHRRTAAQVLG DPO1_DEIRA 725 6 -
GADIHTSTAMRVFG DPO1_LACLC 678 6 -
GKDIHRSTAAEIFG DPO1_HAEIN 733 6 -
GEDLHSFVASRAFG DPO1_MYCTU 705 6 -
GEDLHSFVASRAFG DPO1_MYCLE 712 6 -
HIDIHALTAAYIFN DPO1_TREPA 799 6 -
NVDIHSQTAAEVFG DPO1_ANATH 652 6 -
NKDIHTETASKLFK O51498 710 6 -
KEDIHTQTACQIFN DPO1_RICPR 671 6 -
RQDVHGVTAKLLFG Q55971 774 6 -
GEDIHAFTASQVFN O84500 670 6 -
GRDIHLETSKALFG DPO1_HELPY 697 6 -
GADLHKAVASDAFG DPOL_BPSP1 660 6 -

Motif 5 width=26
Element Seqn Id St Int Rpt
RRQAKAVNFGIVYGISDYGLAQNLNI DPO1_BACST 702 10 -
RRQAKAVNFGIVYGISDYGLAQNLNI O24675 704 10 -
RRQAKAVNFGIVYGISDYGLAQNLNI Q45458 702 10 -
RRQAKAVNFGIVYGISDYGLAQNLNI DPO1_BACCA 703 10 -
RRAAKTVNFGVLYGMSAHRLSQELAI DPO1_THECA 661 10 -
RRAAKTVNFGVLYGMSAHRLSQELAI DPO1_THETH 661 10 -
RRAAKTINFGVLYGMSAHRLSQELAI DPO1_THEAQ 659 10 -
RRAAKTVNFGVLYGMSAHRLSQELGI DPO1_THEFI 659 10 -
RRAAKTINFGVLYGMSAHRLSGELSI DPO1_THEFL 658 10 -
RRQAKAVNFGIVYGISDYGLSQNLGI DPO1_BACSU 706 10 -
RRNAKAVNFGVVYGISDFGLSNNLGI DPO1_STRPN 703 11 -
RRSAKAINFGLIYGMSAFGLARQLNI DPO1_ECOLI 754 10 -
RRVAKTVVFGVIYGISAFGLAQRLGI DPO1_CHLAU 763 10 -
RRAAKTVNFGVLYGMSAHRLSNDLGI DPO1_DEIRA 749 10 -
RRNAKAVNFGVVYGISDFGLARNLGI DPO1_LACLC 703 11 -
RRNAKAINFGLIYGMSAFGLSRQLGI DPO1_HAEIN 757 10 -
RRRVKAMSYGLAYGLSAYGLSQQLKI DPO1_MYCTU 729 10 -
RRRVKAMSYGLAYGLSAYGLATQLKI DPO1_MYCLE 736 10 -
RRIAKTINFGIVYGMSAFRLSDELKI DPO1_TREPA 823 10 -
RSQAKAVNFGIVYGISDYGLARDIKI DPO1_ANATH 676 10 -
RRIAKSINFGIIYRMSDFRLAKELGI O51498 734 10 -
RRKAKAINFGIIYGISAFGLAKQLNV DPO1_RICPR 695 10 -
RNLGKTINFGVIYGMGAQRFARETGI Q55971 796 8 -
RYQAKAVNFGLVYGQQAYGLSKILKI O84500 694 10 -
RSIAKSINFGLVYGMGSKKLSETLNI DPO1_HELPY 718 7 -
RTASKKIQFGIVYQESARGLSEDLRA DPOL_BPSP1 684 10 -

Motif 6 width=12
Element Seqn Id St Int Rpt
YFASFPGVKQYM DPO1_BACST 739 11 -
YFASFPGVRRYM O24675 741 11 -
YFASFPGVKQYM Q45458 739 11 -
YFESFPGVKRYM DPO1_BACCA 740 11 -
YFQSFPKVRAWI DPO1_THECA 698 11 -
YFQSFPKVRAWI DPO1_THETH 698 11 -
YFQSFPKVRAWI DPO1_THEAQ 696 11 -
YFQSFPKVRAWI DPO1_THEFI 696 11 -
YFQSYPKVRAWI DPO1_THEFL 695 11 -
YLESFQGVKAYM DPO1_BACSU 743 11 -
YFERFPGIKNYM DPO1_STRPN 740 11 -
YFERYPGVLEYM DPO1_ECOLI 791 11 -
LFAQFPGIRRYI DPO1_CHLAU 800 11 -
YFATYPGIRRYI DPO1_DEIRA 786 11 -
YFERYPGIKTYM DPO1_LACLC 740 11 -
YFQRYPSVQQFM DPO1_HAEIN 794 11 -
YFARFGGVRDYL DPO1_MYCTU 766 11 -
YFARFGGVRDYL DPO1_MYCLE 773 11 -
YFETYPGVYAFS DPO1_TREPA 860 11 -
YFERYPKVKEYL DPO1_ANATH 713 11 -
YFDSYPKIKEFI O51498 771 11 -
YFAEYKGVQEYM DPO1_RICPR 732 11 -
YHRTYAQVFDYL Q55971 833 11 -
YFARYPLAAEFI O84500 731 11 -
YFKRFPSIKDYL DPO1_HELPY 755 11 -
YFKRFPKVSKWI DPOL_BPSP1 726 16 -

Motif 7 width=12
Element Seqn Id St Int Rpt
GYVTTLLHRRRY DPO1_BACST 761 10 -
GYVTTLLHRRRY O24675 763 10 -
GYVTTLLHRRRY Q45458 761 10 -
GYVTTLLHRRRY DPO1_BACCA 762 10 -
GYVETLFGRRRY DPO1_THECA 720 10 -
GYVETLFGRRRY DPO1_THETH 720 10 -
GYVETLFGRRRY DPO1_THEAQ 718 10 -
GYVETLFGRRRY DPO1_THEFI 718 10 -
GYVETLFGRRRY DPO1_THEFL 717 10 -
GYVTTLMHRRRY DPO1_BACSU 765 10 -
GYVETLFKRRRE DPO1_STRPN 762 10 -
GYVETLDGRRLY DPO1_ECOLI 813 10 -
GYVQTLFGRRRV DPO1_CHLAU 822 10 -
GYVETLYGRRRY DPO1_DEIRA 808 10 -
GFVETMSHRRRK DPO1_LACLC 762 10 -
GYVETLFGRRLY DPO1_HAEIN 816 10 -
GYTSTVLGRRRY DPO1_MYCTU 788 10 -
GYTSTVLGRRRY DPO1_MYCLE 795 10 -
GYVTSLAGRRRY DPO1_TREPA 882 10 -
GFVLTLFNRKRY DPO1_ANATH 735 10 -
GYSETILKRRRY O51498 793 10 -
GYVTNFFGRKCF DPO1_RICPR 754 10 -
GYVTTIVGRRRY Q55971 855 10 -
QKVTTMLGRERI O84500 753 10 -
SKAFTLLGRYRV DPO1_HELPY 777 10 -
STVKTLTGATRN DPOL_BPSP1 748 10 -

Motif 8 width=17
Element Seqn Id St Int Rpt
NTPIQGSAADIIKKAMI DPO1_BACST 793 20 -
NTPIQGSAADIIKKAMI O24675 795 20 -
NTPIQGSAADIIKKAMI Q45458 793 20 -
NTPIQGSAADIIKKAMI DPO1_BACCA 794 20 -
NMPVQGTAADLMKLAMV DPO1_THECA 752 20 -
NMPVQGTAADLMKLAMV DPO1_THETH 752 20 -
NMPVQGTAADLMKLAMV DPO1_THEAQ 750 20 -
NMPVQGTAADLMKIAMV DPO1_THEFI 750 20 -
NMPVQGTAADLMKLAMV DPO1_THEFL 749 20 -
NTPIQGSAADIIKKAMI DPO1_BACSU 797 20 -
NSPIQGSAADILKIAMI DPO1_STRPN 794 20 -
NAPMQGTAADIIKRAMI DPO1_ECOLI 845 20 -
NAPIQGTAADLMKMAMV DPO1_CHLAU 853 19 -
NMPIQGTAADIMKLAMV DPO1_DEIRA 840 20 -
NSPIQGSAADILKIAMI DPO1_LACLC 794 20 -
NAPMQGTAADIIKRAMI DPO1_HAEIN 848 20 -
NAPIQGSAADIIKVAMI DPO1_MYCTU 820 20 -
NAPIQGSAADIIKVAMI DPO1_MYCLE 827 20 -
NTQIQSSAADIVKIAMI DPO1_TREPA 914 20 -
NSPIQGSPADIMKLAMI DPO1_ANATH 767 20 -
NSIIQGSAADIMKIAMV O51498 825 20 -
NAPIQGTNADIIKIAMI DPO1_RICPR 784 18 -
NAPIQGSSADIIKIAMV Q55971 905 38 -
NTRIQGSAAELIKLAML O84500 784 19 -
NAIFQGSASDLLKLGML DPO1_HELPY 808 19 -
NTPIQGTGSDCTLMSLI DPOL_BPSP1 780 20 -

Motif 9 width=14
Element Seqn Id St Int Rpt
RLLLQVHDELILEA DPO1_BACST 823 13 -
RLLLQVHDELILEA O24675 825 13 -
RLLLQVHDELILEA Q45458 823 13 -
RLLLQVHDELILEA DPO1_BACCA 824 13 -
RMLLQVHDELLLEA DPO1_THECA 780 11 -
RMLLQVHDELLLEA DPO1_THETH 780 11 -
RMLLQVHDELVLEA DPO1_THEAQ 778 11 -
HLLLQVHDELVLEV DPO1_THEFI 778 11 -
RMLLQVHDELVLEA DPO1_THEFL 777 11 -
RLLLQVHDELIFEA DPO1_BACSU 827 13 -
KMLLQVHDEIVLEV DPO1_STRPN 824 13 -
RMIMQVHDELVFEV DPO1_ECOLI 875 13 -
RLLLQVHDELIAEA DPO1_CHLAU 883 13 -
RMLLQVHDELLIEA DPO1_DEIRA 868 11 -
KLLLQVHDEIILDV DPO1_LACLC 824 13 -
EMIMQVHDELVFEV DPO1_HAEIN 877 12 -
RMLLQVHDELLFEI DPO1_MYCTU 850 13 -
RMLLQVHDELLFEV DPO1_MYCLE 857 13 -
QLLLQVHDELIFEA DPO1_TREPA 944 13 -
KIILQVHDELLIEA DPO1_ANATH 797 13 -
KILLQVHDEMLIES O51498 855 13 -
RLILQIHDELLFEV DPO1_RICPR 814 13 -
RMLLQVHDELIFEM Q55971 933 11 -
RLLLQIHDELLFEV O84500 814 13 -
RLLLQVHDELIFEI DPO1_HELPY 837 12 -
RICITVHDSIVLDC DPOL_BPSP1 810 13 -