| Literature References | 1. RAWLINGS, N.D. AND BARRETT, A.J.
Families of serine peptidases.
METHODS ENZYMOL. 244 19-61 (1994).
2. RAWLINGS, N.D AND BARRETT, A.J.
Evolutionary families of peptidases.
BIOCHEM.J. 290 205-218 (1993).
3. BODE, W. AND HUBER, R.
Crystal structure ananlysis and refinement of two variants of trigonal
trypsinogen: triginal trypsin and PEG (polyethylene glycol) trypsinogen and
their comparison with orthorhombic trypsin and trigonal trypsinogen.
FEBS LETT. 90 265-269 (1978).
4. KRATZSCHMAR, J., HAENDLER, B., LANGER, G., BOIDOL, W., BRINGMANN, P.,
ALAGON, A., DONNER, P. AND SCHLEUNING, W.D.
The plasminogen activator family from the salivary gland of the vampire
bat Desmodus rotundis: cloning and expression.
GENE 105 229-237 (1991).
5. YOUNG, C.L., BARKER, W.C., TOMASELLI, C.M. AND DAYHOFF, M.O.
In atlas of protein sequence and structure.
DAYHOFF, M.O., ED., VOL.5 SUPPL.(3) P.73 (1978).
|
| Documentation | Proteolytic enzymes that exploit serine in their catalytic activity are
ubiquitous, being found in viruses, bacteria and eukaryotes [1]. They
include a wide range of peptidase activity, including exopeptidase, endo-
peptidase, oligopeptidase and omega-peptidase activity. Over 20 families
(denoted S1 - S27) of serine protease have been identified, these being
grouped into 6 clans (SA, SB, SC, SE, SF and SG) on the basis of structural
similarity and other functional evidence [1]. Structures are known for four
of the clans (SA, SB, SC and SE): these appear to be totally unrelated,
suggesting at least four evolutionary origins of serine peptidases and
possibly many more [1].
Notwithstanding their different evolutionary origins, there are similarities
in the reaction mechanisms of several peptidases. Chymotrypsin, subtilisin
and carboxypeptidase C clans have a catalytic triad of serine, aspartate and
histidine in common: serine acts as a nucleophile, aspartate as an
electrophile, and histidine as a base [1]. The geometric orientations of
the catalytic residues are similar between families, despite different
protein folds [1]. The linear arrangements of the catalytic residues
commonly reflect clan relationships. For example the catalytic triad in
the chymotrypsin clan (SA) is ordered HDS, but is ordered DHS in the
subtilisin clan (SB) and SDH in the carboxypeptidase clan (SC) [1,2].
The trypsin family is almost totally confined to animals, although trypsin-
like enzymes are found in actinomycetes of the genera Streptomyces and
Saccharopolyspora, and in the fungus Fusarium oxysporum [1]. The enzymes
are inherently secreted, being synthesised with a signal peptide that
targets them to the secretory pathway. Animal enzymes are either secreted
directly, packaged into vesicles for regulated secretion, or are retained
in leukocyte granules [1].
Members of the chymotrypsin family may occasionally function intracellularly
(for example, the intracellular digestion of bacteria in neutrophils), but
most function extracellularly, for example in roles such as food digestion,
fibrinolysis and complement activation [1].
The essential catalytic unit of the chymotrypsin family is around 220
amino acids in length, although the protein may be extended at the
N-terminus with unrelated sequences, often containing modules. They are
rarely extended at the C-terminus: exceptions include acrosin, complement
component C2, and coagulation factor X, which has a 16 residue extension
that is removed upon activation [1].
Proteolytic activation of the protein takes place extracellularly, or
sometimes in storage organelles, creating a new N-terminal residue - this is
often isoleucine, but may be leucine, valine or methionine [3]. Salivary
plasminogen activator from vampire bat contains serine as its new N-terminal
residue [2]. The N-terminus forms a salt-bridge with Asp-194, leading to the
formation of the functional active site [1]. The cleaved propeptide can be
as small as two amino acids, but many are much larger peptides that may
contain modules. The cleaved peptide, not uncommonly, remains disulphide-
bonded to the active enzyme [1].
A number of non-functional proteins that have one or more of the active
site residues substituted belong to this family, including haptoglobulin,
azurocidin and apolipoprotein A.
Actinomycete trypsins are too similar to their eukaryotic counterparts to be
consistent with divergence 3500 million years ago when the common precursor
of prokaryotes and eukaryotes is thought to have lived. Hartley attempted
to explain this by suggesting a horizontal gene transfer from the higher
organisms to bacteria [4]. However, Young et al. suggested a horizontal gene
transfer from bacteria to higher organisms around 1300 million years ago,
when mitochondria were introduced into eukaryotes [5]. This is thought to
be a more likely scenario [1].
CHYMOTRYPSIN is a 3-element fingerprint that provides a signature for the
chymotrypsin (S1) family of serine proteases. The fingerprint was derived
from an initial alignment of 26 sequences: the motifs were drawn from
conserved regions around the active site - motif 1 includes the region
encoded by PROSITE pattern TRYPSIN_HIS (PS00134), which contains the
catalytic histidine; motif 2 contains the catalytic aspartate; and motif 3
includes the region encoded by PROSITE pattern TRYPSIN_SER (PS00135), which
contains the catalytic serine. Four iterations on OWL28.2 were required to
reach convergence, at which point a true set comprising 460 sequences was
identified. Twenty six partial matches were also found: 23 of these are
fragments, most of which lack the first motif; 9 sequences lack the second
motif; and 4 lack the final motif.
An update on SPTR37_9f identified a true set of 450 sequences, and 77
partial matches.
|
| Sequence Titles | ACH1_LONAC ACHELASE I PROTEASE (EC 3.4.21.-) - LONOMIA ACHELOUS (GIANT SILKWORM MOTH) (SATURNID MOTH).
ACH2_LONAC ACHELASE II PROTEASE (EC 3.4.21.-) - LONOMIA ACHELOUS (GIANT SILKWORM MOTH) (SATURNID MOTH).
ACRO_HUMAN ACROSIN PRECURSOR (EC 3.4.21.10) - HOMO SAPIENS (HUMAN).
ACRO_MOUSE ACROSIN PRECURSOR (EC 3.4.21.10) - MUS MUSCULUS (MOUSE).
ACRO_PIG ACROSIN PRECURSOR (EC 3.4.21.10) (53 KD FUCOSE-BINDING PROTEIN) - SUS SCROFA (PIG).
ACRO_RABIT ACROSIN PRECURSOR (EC 3.4.21.10) - ORYCTOLAGUS CUNICULUS (RABBIT).
ACRO_RAT ACROSIN PRECURSOR (EC 3.4.21.10) - RATTUS NORVEGICUS (RAT).
ANC1_AGKRH ANCROD (EC 3.4.21.74) (VENOMBIN A) (PROTEIN C ACTIVATOR) (ACC-C) - AGKISTRODON RHODOSTOMA (MALAYAN PIT VIPER) (CALLOSELASMA RHODOSTOMA).
ANC2_AGKRH ANCROD PRECURSOR (EC 3.4.21.74) (VENOMBIN A) (PROTEIN C ACTIVATOR) (ACC-C) - AGKISTRODON RHODOSTOMA (MALAYAN PIT VIPER) (CALLOSELASMA RHODOSTOMA).
ANCR_AGKCO ANCROD (EC 3.4.21.74) (VENOMBIN A) (PROTEIN C ACTIVATOR) (ACC-C) - AGKISTRODON CONTORTRIX CONTORTRIX (SOUTHERN COPPERHEAD).
APOA_HUMAN APOLIPOPROTEIN(A) PRECURSOR (EC 3.4.21.-) (APO(A)) (LP(A)) - HOMO SAPIENS (HUMAN).
BATX_BOTAT BATROXOBIN PRECURSOR (EC 3.4.21.74) (BOTHROPS ATROX SERINE PROTEINASE) (VENOMBIN A) - BOTHROPS ATROX (BARBA AMARILLA) (FER-DE-LANCE).
C1R_HUMAN COMPLEMENT C1R COMPONENT PRECURSOR (EC 3.4.21.41) - HOMO SAPIENS (HUMAN).
C1S_HUMAN COMPLEMENT C1S COMPONENT PRECURSOR (EC 3.4.21.42) (C1 ESTERASE) - HOMO SAPIENS (HUMAN).
CAC3_BOVIN PROPROTEINASE E PRECURSOR (PROCARBOXYPEPTIDASE A COMPLEX COMPONENT III) (PROCARBOXYPEPTIDASE A-S6 SUBUNIT III) (PROCPA-S6 III) - BOS TAURUS (BOVINE).
CAP7_HUMAN AZUROCIDIN PRECURSOR (CATIONIC ANTIMICROBIAL PROTEIN CAP37) (HEPARIN-BINDING PROTEIN) (HBP) - HOMO SAPIENS (HUMAN).
CAP7_PIG AZUROCIDIN (CATIONIC ANTIMICROBIAL PROTEIN CAP37) (HEPARIN-BINDING PROTEIN) (HBP) - SUS SCROFA (PIG).
CASP_MESAU CALCIUM-DEPENDENT SERINE PROTEINASE PRECURSOR (EC 3.4.21.-) (CASP) - MESOCRICETUS AURATUS (GOLDEN HAMSTER).
CATG_HUMAN CATHEPSIN G PRECURSOR (EC 3.4.21.20) - HOMO SAPIENS (HUMAN).
CATG_MOUSE CATHEPSIN G PRECURSOR (EC 3.4.21.20) (VIMENTIN-SPECIFIC PROTEASE) (VSP) - MUS MUSCULUS (MOUSE).
CERC_SCHMA CERCARIAL PROTEASE PRECURSOR (EC 3.4.21.-) (CERCARIAL ELASTASE) - SCHISTOSOMA MANSONI (BLOOD FLUKE).
CFAB_HUMAN COMPLEMENT FACTOR B PRECURSOR (EC 3.4.21.47) (C3/C5 CONVERTASE) (PROPERDIN FACTOR B) (GLYCINE-RICH BETA GLYCOPROTEIN) (GBG) (PBF2) - HOMO SAPIENS (HUMAN).
CFAB_MOUSE COMPLEMENT FACTOR B PRECURSOR (EC 3.4.21.47) (C3/C5 CONVERTASE) - MUS MUSCULUS (MOUSE).
CFAD_HUMAN COMPLEMENT FACTOR D PRECURSOR (EC 3.4.21.46) (C3 CONVERTASE ACTIVATOR) (PROPERDIN FACTOR D) (ADIPSIN) - HOMO SAPIENS (HUMAN).
CFAD_MOUSE COMPLEMENT FACTOR D PRECURSOR (EC 3.4.21.46) (C3 CONVERTASE ACTIVATOR) (PROPERDIN FACTOR D) (ADIPSIN) (28 KD PROTEIN, ADIPOCYTE) - MUS MUSCULUS (MOUSE).
CFAD_PIG COMPLEMENT FACTOR D PRECURSOR (EC 3.4.21.46) (C3 CONVERTASE ACTIVATOR) (PROPERDIN FACTOR D) (ADIPSIN) - SUS SCROFA (PIG).
CFAD_RAT COMPLEMENT FACTOR D PRECURSOR (EC 3.4.21.46) (C3 CONVERTASE ACTIVATOR) (PROPERDIN FACTOR D) (ADIPSIN) (ENDOGENOUS VASCULAR ELASTASE) - RATTUS NORVEGICUS (RAT).
CFAI_HUMAN COMPLEMENT FACTOR I PRECURSOR (EC 3.4.21.45) (C3B/C4B INACTIVATOR).
CLCR_RAT CALDECRIN PRECURSOR (EC 3.4.21.-) (SERUM CALCIUM-DECREASING FACTOR) (ELASTASE IV) - RATTUS NORVEGICUS (RAT).
CO2_HUMAN COMPLEMENT C2 PRECURSOR (EC 3.4.21.43) (C3/C5 CONVERTASE) - HOMO SAPIENS (HUMAN).
CO2_MOUSE COMPLEMENT C2 PRECURSOR (EC 3.4.21.43) (C3/C5 CONVERTASE) - MUS MUSCULUS (MOUSE).
COGS_HYPLI COLLAGENASE PRECURSOR (EC 3.4.21.-) (HYPODERMIN C) (HC) - HYPODERMA LINEATUM (EARLY CATTLE GRUB) (COMMON CATTLE GRUB).
COGS_UCAPU BRACHYURIN (EC 3.4.21.32) (COLLAGENOLYTIC PROTEASE) - UCA PUGILATOR (ATLANTIC SAND FIDDLER CRAB) (CELUCA PUGILATOR).
CRAR_HUMAN COMPLEMENT-ACTIVATING COMPONENT OF RA-REACTIVE FACTOR PRECURSOR (EC 3.4.21.-) (RA-REACTIVE FACTOR SERINE PROTEASE P100) (RARF) (MANNOSE-BINDING PROTEIN ASSOCIATED SERINE PROTEASE) (MASP) - HOMO SAPIENS (HUMAN).
CRAR_MOUSE COMPLEMENT-ACTIVATING COMPONENT OF RA-REACTIVE FACTOR PRECURSOR (EC 3.4.21.-) (RA-REACTIVE FACTOR SERINE PROTEASE P100) (RARF) - MUS MUSCULUS (MOUSE).
CTR1_ANOGA CHYMOTRYPSIN 1 PRECURSOR (EC 3.4.21.1) - ANOPHELES GAMBIAE (AFRICAN MALARIA MOSQUITO).
CTR1_PENVA CHYMOTRYPSIN BI PRECURSOR (EC 3.4.21.1) - PENAEUS VANNAMEI (PENOEID SHRIMP) (EUROPEAN WHITE SHRIMP).
CTR2_ANOGA CHYMOTRYPSIN 2 PRECURSOR (EC 3.4.21.1) - ANOPHELES GAMBIAE (AFRICAN MALARIA MOSQUITO).
CTR2_CANFA CHYMOTRYPSINOGEN 2 PRECURSOR (EC 3.4.21.1) - CANIS FAMILIARIS (DOG).
CTR2_PENVA CHYMOTRYPSIN BII PRECURSOR (EC 3.4.21.1) - PENAEUS VANNAMEI (PENOEID SHRIMP) (EUROPEAN WHITE SHRIMP).
CTR2_VESCR CHYMOTRYPSIN II (EC 3.4.21.1) - VESPA CRABRO (EUROPEAN HORNET).
CTR2_VESOR CHYMOTRYPSIN II (EC 3.4.21.1) - VESPA ORIENTALIS (ORIENTAL HORNET).
CTRA_BOVIN CHYMOTRYPSINOGEN A (EC 3.4.21.1) - BOS TAURUS (BOVINE).
CTRA_GADMO CHYMOTRYPSIN A PRECURSOR (EC 3.4.21.1) - GADUS MORHUA (ATLANTIC COD).
CTRB_BOVIN CHYMOTRYPSINOGEN B (EC 3.4.21.1) - BOS TAURUS (BOVINE).
CTRB_GADMO CHYMOTRYPSIN B (EC 3.4.21.1) - GADUS MORHUA (ATLANTIC COD).
CTRB_HUMAN CHYMOTRYPSINOGEN B PRECURSOR (EC 3.4.21.1) - HOMO SAPIENS (HUMAN).
CTRB_RAT CHYMOTRYPSINOGEN B PRECURSOR (EC 3.4.21.1) - RATTUS NORVEGICUS (RAT).
CTRL_HALRU CHYMOTRYPSIN-LIKE SERINE PROTEINASE PRECURSOR (EC 3.4.21.-) - HALIOTIS RUFESCENS (CALIFORNIA RED ABALONE).
CTRL_HUMAN CHYMOTRYPSIN-LIKE PROTEASE CTRL-1 PRECURSOR (EC 3.4.21.-) - HOMO SAPIENS (HUMAN).
DDN1_BOVIN DUODENASE I (EC 3.4.21.-) (DUODENUM SERINE PROTEASE) - BOS TAURUS (BOVINE).
DEF3_DERFA MITE ALLERGEN DER F 3 PRECURSOR (EC 3.4.21.-) (DER F III) - DERMATOPHAGOIDES FARINAE (HOUSE-DUST MITE).
DER3_DERPT MITE ALLERGEN DER P 3 PRECURSOR (EC 3.4.21.-) (DER P III) - DERMATOPHAGOIDES PTERONYSSINUS (HOUSE-DUST MITE).
EAST_DROME SERINE PROTEASE EASTER PRECURSOR (EC 3.4.21.-) - DROSOPHILA MELANOGASTER (FRUIT FLY).
EL1_BOVIN ELASTASE 1 PRECURSOR (EC 3.4.21.36) - BOS TAURUS (BOVINE).
EL1_PIG ELASTASE 1 PRECURSOR (EC 3.4.21.36) - SUS SCROFA (PIG).
EL1_RAT ELASTASE 1 PRECURSOR (EC 3.4.21.36) - RATTUS NORVEGICUS (RAT).
EL2A_HUMAN ELASTASE 2A PRECURSOR (EC 3.4.21.71) - HOMO SAPIENS (HUMAN).
EL2B_HUMAN ELASTASE 2B PRECURSOR (EC 3.4.21.71) - HOMO SAPIENS (HUMAN).
EL2_BOVIN ELASTASE 2 PRECURSOR (EC 3.4.21.71) - BOS TAURUS (BOVINE).
EL2_MOUSE ELASTASE 2 PRECURSOR (EC 3.4.21.71) - MUS MUSCULUS (MOUSE).
EL2_PIG ELASTASE 2 PRECURSOR (EC 3.4.21.71) - SUS SCROFA (PIG).
EL2_RAT ELASTASE 2 PRECURSOR (EC 3.4.21.71) - RATTUS NORVEGICUS (RAT).
EL3A_HUMAN ELASTASE IIIA PRECURSOR (EC 3.4.21.70) (PROTEASE E) - HOMO SAPIENS (HUMAN).
EL3B_HUMAN ELASTASE IIIB PRECURSOR (EC 3.4.21.70) (PROTEASE E) - HOMO SAPIENS (HUMAN).
ELNE_HUMAN LEUKOCYTE ELASTASE PRECURSOR (EC 3.4.21.37) (NEUTROPHIL ELASTASE) (PMN ELASTASE) (BONE MARROW SERINE PROTEASE) (MEDULLASIN) - HOMO SAPIENS (HUMAN).
ENTK_BOVIN ENTEROPEPTIDASE PRECURSOR (EC 3.4.21.9) (ENTEROKINASE).
ENTK_HUMAN ENTEROPEPTIDASE PRECURSOR (EC 3.4.21.9) (ENTEROKINASE).
ENTK_MOUSE ENTEROPEPTIDASE (EC 3.4.21.9) (ENTEROKINASE).
ENTK_PIG ENTEROPEPTIDASE PRECURSOR (EC 3.4.21.9) (ENTEROKINASE).
ESTA_CANFA ARGININE ESTERASE PRECURSOR (EC 3.4.21.35) - CANIS FAMILIARIS (DOG).
FA10_BOVIN COAGULATION FACTOR X PRECURSOR (EC 3.4.21.6) (STUART FACTOR) - BOS TAURUS (BOVINE).
FA10_CHICK COAGULATION FACTOR X PRECURSOR (EC 3.4.21.6) (STUART FACTOR) (VIRUS ACTIVATING PROTEASE) (VAP) - GALLUS GALLUS (CHICKEN).
FA10_HUMAN COAGULATION FACTOR X PRECURSOR (EC 3.4.21.6) (STUART FACTOR) - HOMO SAPIENS (HUMAN).
FA10_RABIT COAGULATION FACTOR X PRECURSOR (EC 3.4.21.6) (STUART FACTOR) - ORYCTOLAGUS CUNICULUS (RABBIT).
FA11_HUMAN COAGULATION FACTOR XI PRECURSOR (EC 3.4.21.27) (PLASMA THROMBOPLASTIN ANTECEDENT) (PTA) - HOMO SAPIENS (HUMAN).
FA12_HUMAN COAGULATION FACTOR XII PRECURSOR (EC 3.4.21.38) (HAGEMAN FACTOR) (HAF) - HOMO SAPIENS (HUMAN).
FA7_BOVIN COAGULATION FACTOR VII (EC 3.4.21.21) - BOS TAURUS (BOVINE).
FA7_HUMAN COAGULATION FACTOR VII PRECURSOR (EC 3.4.21.21) (EPTACOG ALFA) - HOMO SAPIENS (HUMAN).
FA7_MOUSE COAGULATION FACTOR VII PRECURSOR (EC 3.4.21.21) - MUS MUSCULUS (MOUSE).
FA7_RABIT COAGULATION FACTOR VII PRECURSOR (EC 3.4.21.21) - ORYCTOLAGUS CUNICULUS (RABBIT).
FA9_BOVIN COAGULATION FACTOR IX (EC 3.4.21.22) (CHRISTMAS FACTOR) - BOS TAURUS (BOVINE).
FA9_CANFA COAGULATION FACTOR IX PRECURSOR (EC 3.4.21.22) (CHRISTMAS FACTOR) - CANIS FAMILIARIS (DOG).
FA9_HUMAN COAGULATION FACTOR IX PRECURSOR (EC 3.4.21.22) (CHRISTMAS FACTOR) - HOMO SAPIENS (HUMAN).
FLVB_TRIFL FLAVOXOBIN PRECURSOR (EC 3.4.21.-) - TRIMERESURUS FLAVOVIRIDIS (HABU).
GRAC_MOUSE GRANZYME C PRECURSOR (EC 3.4.21.-) (CYTOTOXIC CELL PROTEASE 2) (CCP2) (B10) - MUS MUSCULUS (MOUSE).
GRAD_MOUSE GRANZYME D PRECURSOR (EC 3.4.21.-) - MUS MUSCULUS (MOUSE).
GRAE_MOUSE GRANZYME E PRECURSOR (EC 3.4.21.-) (CYTOTOXIC CELL PROTEASE 3) (CCP3) (CTL SERINE PROTEASE 2) (D12) (CYTOTOXIC SERINE PROTEASE 2) (MCSP2) - MUS MUSCULUS (MOUSE).
GRAF_MOUSE GRANZYME F PRECURSOR (EC 3.4.21.-) (CYTOTOXIC CELL PROTEASE 4) (CCP4) (CTL SERINE PROTEASE 3) (C134) (CYTOTOXIC SERINE PROTEASE 3) (MCSP3) - MUS MUSCULUS (MOUSE).
GRAG_MOUSE GRANZYME G PRECURSOR (EC 3.4.21.-) (CTL SERINE PROTEASE 1) (MCSP-1) - MUS MUSCULUS (MOUSE).
GRAH_HUMAN GRANZYME H PRECURSOR (EC 3.4.21.-) (CYTOTOXIC T-LYMPHOCYTE PROTEINASE) (CATHEPSIN G-LIKE 2) (CTSGL2) (CCP-X) (CYTOTOXIC SERINE PROTEASE-C) (CSP-C) - HOMO SAPIENS (HUMAN).
GRAK_MOUSE GRANZYME K PRECURSOR (EC 3.4.21.-) - MUS MUSCULUS (MOUSE).
GRAK_RAT GRANZYME K PRECURSOR (EC 3.4.21.-) (NK-TRYPTASE-2) (NK-TRYP-2) - RATTUS NORVEGICUS (RAT).
GRAM_HUMAN GRANZYME M PRECURSOR (EC 3.4.21.-) (MET-ASE) (NATURAL KILLER CELL GRANULAR PROTEASE) (HU-MET-1) (MET-1 SERINE PROTEASE) - HOMO SAPIENS (HUMAN).
GRL1_RAT GRANZYME-LIKE PROTEIN I PRECURSOR (EC 3.4.21.-) - RATTUS NORVEGICUS (RAT).
GRL2_RAT GRANZYME-LIKE PROTEIN II PRECURSOR (EC 3.4.21.-) - RATTUS NORVEGICUS (RAT).
HAYS_AGKHA HALYSTASE (EC 3.4.21.-) - AGKISTRODON HALYS BLOMHOFFI (MAMUSHI) (GLOYDIUS BLOMHOFFII).
HEPS_HUMAN SERINE PROTEASE HEPSIN (EC 3.4.21.-) (TRANSMEMBRANE PROTEASE, SERINE 1) - HOMO SAPIENS (HUMAN).
HEPS_MOUSE SERINE PROTEASE HEPSIN (EC 3.4.21.-) - MUS MUSCULUS (MOUSE).
HEPS_RAT SERINE PROTEASE HEPSIN (EC 3.4.21.-) - RATTUS NORVEGICUS (RAT).
HGFA_HUMAN HEPATOCYTE GROWTH FACTOR ACTIVATOR PRECURSOR (EC 3.4.21.-) (HGF ACTIVATOR) - HOMO SAPIENS (HUMAN).
HGFL_HUMAN HEPATOCYTE GROWTH FACTOR-LIKE PROTEIN PRECURSOR (MACROPHAGE STIMULATORY PROTEIN) (MSP) (MACROPHAGE STIMULATING PROTEIN) - HOMO SAPIENS (HUMAN).
HGFL_MOUSE HEPATOCYTE GROWTH FACTOR-LIKE PROTEIN PRECURSOR (MACROPHAGE STIMULATORY PROTEIN) (MSP) - MUS MUSCULUS (MOUSE).
HGF_HUMAN HEPATOCYTE GROWTH FACTOR PRECURSOR (SCATTER FACTOR) (SF) (HEPATOPOEITIN A) - HOMO SAPIENS (HUMAN).
HGF_MOUSE HEPATOCYTE GROWTH FACTOR PRECURSOR (SCATTER FACTOR) (SF) (HEPATOPOEITIN A) - MUS MUSCULUS (MOUSE).
HGF_RAT HEPATOCYTE GROWTH FACTOR PRECURSOR (SCATTER FACTOR) (SF) (HEPATOPOEITIN A) - RATTUS NORVEGICUS (RAT).
HPT1_HUMAN HAPTOGLOBIN-1 PRECURSOR - HOMO SAPIENS (HUMAN).
HPT2_HUMAN HAPTOGLOBIN-2 PRECURSOR - HOMO SAPIENS (HUMAN).
HPTR_HUMAN HAPTOGLOBIN-RELATED PROTEIN PRECURSOR - HOMO SAPIENS (HUMAN).
HPT_ATEGE HAPTOGLOBIN PRECURSOR - ATELES GEOFFROYI (BLACK-HANDED SPIDER MONKEY).
HPT_CANFA HAPTOGLOBIN ALPHA AND BETA CHAINS - CANIS FAMILIARIS (DOG).
HPT_MUSSA HAPTOGLOBIN PRECURSOR - MUS SAXICOLA (SPINY MOUSE).
HPT_RAT HAPTOGLOBIN PRECURSOR - RATTUS NORVEGICUS (RAT).
HYPA_HYPLI HYPODERMIN A PRECURSOR (EC 3.4.21.-) (HA) - HYPODERMA LINEATUM (EARLY CATTLE GRUB) (COMMON CATTLE GRUB).
HYPB_HYPLI HYPODERMIN B PRECURSOR (EC 3.4.21.-) (HB) - HYPODERMA LINEATUM (EARLY CATTLE GRUB) (COMMON CATTLE GRUB).
KAL_HUMAN PLASMA KALLIKREIN PRECURSOR (EC 3.4.21.34) (PLASMA PREKALLIKREIN) (KININOGENIN) (FLETCHER FACTOR) - HOMO SAPIENS (HUMAN).
KAL_MOUSE PLASMA KALLIKREIN PRECURSOR (EC 3.4.21.34) (PLASMA PREKALLIKREIN) (KININOGENIN) (FLETCHER FACTOR) - MUS MUSCULUS (MOUSE).
KAL_RAT PLASMA KALLIKREIN PRECURSOR (EC 3.4.21.34) (PLASMA PREKALLIKREIN) (KININOGENIN) (FLETCHER FACTOR) - RATTUS NORVEGICUS (RAT).
KLK1_HUMAN GLANDULAR KALLIKREIN 1 PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (KIDNEY/PANCREAS/SALIVARY GLAND KALLIKREIN) - HOMO SAPIENS (HUMAN).
KLK1_MACFA GLANDULAR KALLIKREIN 1 PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (KIDNEY/PANCREAS/SALIVARY GLAND KALLIKREIN) - MACACA FASCICULARIS (CRAB EATING MACAQUE) (CYNOMOLGUS MONKEY).
KLK1_MOUSE GLANDULAR KALLIKREIN K1 PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (MGK-6) (RENAL KALLIKREIN) (KAL-B) - MUS MUSCULUS (MOUSE).
KLK1_PAPHA GLANDULAR KALLIKREIN 1 PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (KIDNEY/PANCREAS/SALIVARY GLAND KALLIKREIN) - PAPIO HAMADRYAS (HAMADRYAS BABOON).
KLK1_RAT GLANDULAR KALLIKREIN, PANCREATIC 1 PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (PS KALLIKREIN) (RGK-1) - RATTUS NORVEGICUS (RAT).
KLK2_CAVPO GLANDULAR KALLIKREIN, PROSTATIC (EC 3.4.21.35) (TISSUE KALLIKREIN) (PROSTATE ESTERASE) - CAVIA PORCELLUS (GUINEA PIG).
KLK2_HUMAN GLANDULAR KALLIKREIN 2 PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (PROSTATE) (HGK-1) - HOMO SAPIENS (HUMAN).
KLK2_RAT TONIN PRECURSOR (EC 3.4.21.35) (ESTERASE 1) (S2 KALLIKREIN) (RGK-2) (RSKG-5) - RATTUS NORVEGICUS (RAT).
KLK3_MOUSE GLANDULAR KALLIKREIN K3 PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (MGK-3) (7S NERVE GROWTH FACTOR GAMMA CHAIN) (GAMMA-NGF) - MUS MUSCULUS (MOUSE).
KLK4_MOUSE 7S NERVE GROWTH FACTOR ALPHA CHAIN PRECURSOR (ALPHA-NGF) - MUS MUSCULUS (MOUSE).
KLK5_MOUSE GLANDULAR KALLIKREIN K5 PRECURSOR (EC 3.4.21.35), SUBMANDIBULAR (TISSUE KALLIKREIN) (MGK-5) - MUS MUSCULUS (MOUSE).
KLK6_MOUSE GLANDULAR KALLIKREIN K6 PRECURSOR (EC 3.4.21.35), SUBMANDIBULAR (TISSUE KALLIKREIN) (MGK-1) - MUS MUSCULUS (MOUSE).
KLK7_RAT GLANDULAR KALLIKREIN 7, SUBMANDIBULAR/RENAL PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (RGK-7) (RSKG-7) (ESTERASE B) (PROTEINASE A) - RATTUS NORVEGICUS (RAT).
KLK8_MOUSE GLANDULAR KALLIKREIN K8 PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (MGK-8) - MUS MUSCULUS (MOUSE).
KLK8_RAT GLANDULAR KALLIKREIN 8, PROSTATIC PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (P1 KALLIKREIN) (RGK-8) - RATTUS NORVEGICUS (RAT).
KLK9_MOUSE GLANDULAR KALLIKREIN K9 PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (MGK-9) (EPIDERMAL GROWTH FACTOR-BINDING PROTEIN TYPE C) (EGF-BP C) - MUS MUSCULUS (MOUSE).
KLK9_RAT GLANDULAR KALLIKREIN 9, SUBMANDIBULAR PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (S3 KALLIKREIN) (SUBMANDIBULAR ENZYMATIC VASOCONSTRICTOR) (SEV) (KLK-S3) - RATTUS NORVEGICUS (RAT).
KLKA_MOUSE GLANDULAR KALLIKREIN K11 PRECURSOR (EC 3.4.21.35), SUBMANDIBULAR (TISSUE KALLIKREIN) (MGK-11) - MUS MUSCULUS (MOUSE).
KLKB_RAT GLANDULAR KALLIKREIN 12, SUBMANDIBULAR/RENAL PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (RSKG-3) - RATTUS NORVEGICUS (RAT).
KLKC_MOUSE GLANDULAR KALLIKREIN K13 PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (MGK-13) (EPIDERMAL GROWTH FACTOR-BINDING PROTEIN TYPE B) (EGF-BP B) (PRORENIN-CONVERTING ENZYME) (PRECE) - MUS MUSCULUS (MOUSE).
KLKF_MOUSE GAMMA-RENIN, SUBMANDIBULAR GLAND PRECURSOR (EC 3.4.21.54) (MGK-16) - MUS MUSCULUS (MOUSE).
KLKL_MOUSE GLANDULAR KALLIKREIN K22 PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (MGK-22) (EPIDERMAL GROWTH FACTOR-BINDING PROTEIN TYPE A) (EGF-BP A) (NERVE GROWTH FACTOR BETA CHAIN ENDOPEPTIDASE) (BETA-NGF- ENDOPEPTIDASE) - MUS MUSCULUS (MOUSE).
KLKR_PRANA GLANDULAR KALLIKREIN, RENAL PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) - PRAOMYS NATALENSIS (AFRICAN SOFT-FURRED RAT) (MASTOMYS NATALENSIS).
KLKZ_MOUSE GLANDULAR KALLIKREIN K26 PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (PRORENIN-CONVERTING ENZYME 2) (PRECE-2) - MUS MUSCULUS (MOUSE).
KLK_PIG GLANDULAR KALLIKREIN (EC 3.4.21.35) (TISSUE KALLIKREIN) - SUS SCROFA (PIG).
LFC_TACTR LIMULUS CLOTTING FACTOR C PRECURSOR (EC 3.4.21.84) - TACHYPLEUS TRIDENTATUS (JAPANESE HORSESHOE CRAB).
MCT1_CANFA CHYMASE PRECURSOR (EC 3.4.21.39) (MAST CELL PROTEASE I) - CANIS FAMILIARIS (DOG).
MCT1_HUMAN CHYMASE PRECURSOR (EC 3.4.21.39) (MAST CELL PROTEASE I) - HOMO SAPIENS (HUMAN).
MCT1_MACFA CHYMASE PRECURSOR (EC 3.4.21.39) (MAST CELL PROTEASE I) - MACACA FASCICULARIS (CRAB EATING MACAQUE) (CYNOMOLGUS MONKEY).
MCT1_MERUN MAST CELL PROTEASE 1 PRECURSOR (EC 3.4.21.-) - MERIONES UNGUICULATUS (MONGOLIAN JIRD).
MCT1_MOUSE MAST CELL PROTEASE 1 PRECURSOR (EC 3.4.21.-) (MMCP-1) - MUS MUSCULUS (MOUSE).
MCT1_PAPHA CHYMASE PRECURSOR (EC 3.4.21.39) (MAST CELL PROTEASE I) - PAPIO HAMADRYAS (HAMADRYAS BABOON).
MCT1_RAT MAST CELL PROTEASE I PRECURSOR (EC 3.4.21.39) (RMCP-I) (CHYMASE) - RATTUS NORVEGICUS (RAT).
MCT1_SHEEP MAST CELL PROTEASE 1A PRECURSOR (EC 3.4.21.-) (SMCP-1A) - OVIS ARIES (SHEEP).
MCT2_MERUN MAST CELL PROTEASE 2 PRECURSOR (EC 3.4.21.-) - MERIONES UNGUICULATUS (MONGOLIAN JIRD).
MCT2_MOUSE MAST CELL PROTEASE 2 PRECURSOR (EC 3.4.21.-) (MMCP-2) - MUS MUSCULUS (MOUSE).
MCT2_RAT MAST CELL PROTEASE II PRECURSOR (EC 3.4.21.-) (RMCP-II) (GROUP- SPECIFIC PROTEASE) - RATTUS NORVEGICUS (RAT).
MCT3_RAT MAST CELL PROTEASE III PRECURSOR (EC 3.4.21.-) (RMCP-III) - RATTUS NORVEGICUS (RAT).
MCT4_MOUSE MAST CELL PROTEASE 4 PRECURSOR (EC 3.4.21.-) (MMCP-4) (SEROSAL MAST CELL PROTEASE) (MSMCP) - MUS MUSCULUS (MOUSE).
MCT5_MOUSE MAST CELL PROTEASE 5 PRECURSOR (EC 3.4.21.-) (MMCP-5) (MAST CELL CHYMASE 1) - MUS MUSCULUS (MOUSE).
MCT6_MOUSE MAST CELL PROTEASE 6 PRECURSOR (EC 3.4.21.-) (MMCP-6) (TRYPTASE) - MUS MUSCULUS (MOUSE).
MCT7_MOUSE MAST CELL PROTEASE 7 PRECURSOR (EC 3.4.21.-) (MMCP-7) (TRYPTASE) - MUS MUSCULUS (MOUSE).
MCT7_RAT MAST CELL PROTEASE 7 PRECURSOR (EC 3.4.21.-) (RMCP-7) (TRYPTASE, SKIN) - RATTUS NORVEGICUS (RAT).
MCT8_MOUSE MAST CELL PROTEASE 8 PRECURSOR (EC 3.4.21.-) (MMCP-8) - MUS MUSCULUS (MOUSE).
MCT9_MOUSE MAST CELL PROTEASE 9 PRECURSOR (EC 3.4.21.-) (MMCP-9) - MUS MUSCULUS (MOUSE).
MCTX_MOUSE MAST CELL PROTEASE-LIKE PROTEIN PRECURSOR (EC 3.4.21.-) - MUS MUSCULUS (MOUSE).
NDL_DROME SERINE PROTEASE NUDEL PRECURSOR (EC 3.4.21.-).
O00187 MASP-2 PROTEIN PRECURSOR - HOMO SAPIENS (HUMAN).
O01309 TRYPSINOGEN - BOTRYLLUS SCHLOSSERI.
O01310 TRYPSINOGEN - BOTRYLLUS SCHLOSSERI.
O01566 SIMILARITY TO THE PEPTIDASE FAMILLY S1 - CAENORHABDITIS ELEGANS.
O01654 ASMASPA - HALOCYNTHIA RORETZI (SEA SQUIRT).
O01887 SIMILAR TO THE PEPTIDASE FAMILY S1 - CAENORHABDITIS ELEGANS.
O02569 EARLY TRYPSIN PRECURSOR - CULEX QUINQUEFASCIATUS (SOUTHERN HOUSE MOSQUITO).
O02570 LATE TRYPSIN PRECURSOR - CULEX QUINQUEFASCIATUS (SOUTHERN HOUSE MOSQUITO).
O08643 LYMPHOCTYE MET-ASE 1 PRECURSOR (LMET-1) - MUS MUSCULUS (MOUSE).
O08732 CHYMASE - MESOCRICETUS AURATUS (GOLDEN HAMSTER).
O08762 PROTEASE, SERINE, 12 NEUROTRYPSIN, (MOTOPSIN) PRECURSOR - MUS MUSCULUS (MOUSE).
O08809 PROTEINASE 3 (PRE-PRO-PROTEINASE 3) - MUS MUSCULUS (MOUSE).
O13057 SERINE PROTEASE PRECURSOR - TRIMERESURUS FLAVOVIRIDIS (HABU).
O13058 SERINE PROTEASE PRECURSOR - TRIMERESURUS FLAVOVIRIDIS (HABU).
O13059 SERINE PROTEASE PRECURSOR - TRIMERESURUS GRAMINEUS (INDIAN GREEN TREE VIPER) (GREEN HABU SNAKE).
O13060 SERINE PROTEASE PRECURSOR - TRIMERESURUS GRAMINEUS (INDIAN GREEN TREE VIPER) (GREEN HABU SNAKE).
O13061 SERINE PROTEASE PRECURSOR - TRIMERESURUS GRAMINEUS (INDIAN GREEN TREE VIPER) (GREEN HABU SNAKE).
O13062 SERINE PROTEASE PRECURSOR - TRIMERESURUS GRAMINEUS (INDIAN GREEN TREE VIPER) (GREEN HABU SNAKE).
O13063 SERINE PROTEASE PRECURSOR - TRIMERESURUS GRAMINEUS (INDIAN GREEN TREE VIPER) (GREEN HABU SNAKE).
O13069 KN-BJ2 PRECURSOR - BOTHROPS JARARACA (JARARACA).
O15944 26KDA PROTEASE - SARCOPHAGA PEREGRINA (FLESH FLY).
O16126 TRYPSINOGEN 1 PRECURSOR - BOLTENIA VILLOSA.
O16133 TRYPSIN - ANOPHELES STEPHENSI (INDO-PAKISTAN MALARIA MOSQUITO).
O17489 SERINE PROTEASE 14D - ANOPHELES GAMBIAE (AFRICAN MALARIA MOSQUITO).
O17490 INFECTION RESPONSIVE SERINE PROTEASE LIKE PROTEIN PRECURSOR - ANOPHELES GAMBIAE (AFRICAN MALARIA MOSQUITO).
O18434 TRYPSIN-LIKE PROTEASE PRECURSOR - HELICOVERPA ARMIGERA (COTTON BOLLWORM).
O18435 TRYPSIN-LIKE PROTEASE PRECURSOR - HELICOVERPA ARMIGERA (COTTON BOLLWORM).
O18436 TRYPSIN-LIKE PROTEASE PRECURSOR - HELICOVERPA ARMIGERA (COTTON BOLLWORM).
O18438 CHYMOTRYPSIN-LIKE PROTEASE PRECURSOR - HELICOVERPA ARMIGERA (COTTON BOLLWORM).
O18440 TRYPSIN-LIKE PROTEASE PRECURSOR - HELICOVERPA ARMIGERA (COTTON BOLLWORM).
O18445 CHYMOTRYPSIN-LIKE PROTEASE PRECURSOR - HELICOVERPA ARMIGERA (COTTON BOLLWORM).
O18447 TRYPSIN-LIKE PROTEASE PRECURSOR - HELICOVERPA ARMIGERA (COTTON BOLLWORM).
O18450 CHYMOTRYPSIN-LIKE PROTEASE PRECURSOR - HELICOVERPA ARMIGERA (COTTON BOLLWORM).
O18459 SERINE PROTEINASE PRECURSOR - HETERODERA GLYCINES.
O18599 DVTRY-1 TRYPSIN PRECUSOR - DROSOPHILA VIRILIS (FRUIT FLY).
O18600 DVTRY-2 TRYPSIN PRECUSOR - DROSOPHILA VIRILIS (FRUIT FLY).
O18783 PLASMINOGEN - MACROPUS EUGENII (TAMMAR WALLABY).
O34289 SERINE PROTEASE-LIKE PROTEIN PRECURSOR - SALVELINUS FONTINALIS (BROOK TROUT).
O35086 HAPTOGLOBIN PRECURSOR - MESOCRICETUS AURATUS (GOLDEN HAMSTER).
O35342 SKELETAL MUSCLE NEUTRAL PROTEASE MEKRATIN - MESOCRICETUS AURATUS (GOLDEN HAMSTER).
O35727 FACTOR XII - MUS MUSCULUS (MOUSE).
O42158 TRYPSINOGEN A2 PRECURSOR - PETROMYZON MARINUS (SEA LAMPREY).
O42207 CAPILLARY PERMEABILITY-INCREASING ENZYME-2 - GLOYDIUS USSURIENSIS.
O42272 SERINE PROTEASE - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
O42608 TRYPSINOGEN A3 PRECURSOR - PETROMYZON MARINUS (SEA LAMPREY).
O44330 HEMOCYTE PROTEASE-1 - MANDUCA SEXTA (TOBACCO HAWKMOTH) (TOBACCO HORNWORM).
O44331 HEMOCYTE PROTEASE-2 - MANDUCA SEXTA (TOBACCO HAWKMOTH) (TOBACCO HORNWORM).
O44332 HEMOCYTE PROTEASE-3 - MANDUCA SEXTA (TOBACCO HAWKMOTH) (TOBACCO HORNWORM).
O44333 HEMOCYTE PROTEASE-4 - MANDUCA SEXTA (TOBACCO HAWKMOTH) (TOBACCO HORNWORM).
O45048 SERINE PROTEINASE - ANOPHELES GAMBIAE (AFRICAN MALARIA MOSQUITO).
O46164 SERINE PROTEASE-LIKE PROTEIN PRECURSOR - SCHISTOCERCA GREGARIA (DESERT LOCUST).
O46644 ELASTASE I PRECURSOR - MACACA FASCICULARIS (CRAB EATING MACAQUE) (CYNOMOLGUS MONKEY).
O46683 MAST CELL PROTEINASE-3 - OVIS ARIES (SHEEP).
O54740 COAGULATION FACTOR X PRECURSOR (EC 3.4.21.6) - MUS MUSCULUS (MOUSE).
O54854 MYELENCEPHALON SPECIFIC PROTEASE - RATTUS NORVEGICUS (RAT).
O60235 AIRWAY TRYPSIN-LIKE PROTEASE - HOMO SAPIENS (HUMAN).
O60259 NEUROPSIN PRECURSOR (EC 3.4.21.-) (NP) - HOMO SAPIENS (HUMAN).
O69997 PUTATIVE SERINE PROTEASE - STREPTOMYCES COELICOLOR.
O70164 CHYMASE 2 - MESOCRICETUS AURATUS (GOLDEN HAMSTER).
O70169 TESTICULAR SERINE PROTEASE 1 (TESP1) - MUS MUSCULUS (MOUSE).
O70170 TESTICULAR SERINE PROTEASE 2 (TESP2) - MUS MUSCULUS (MOUSE).
O70500 VASCULAR CHYMASE - RATTUS NORVEGICUS (RAT).
O70542 SERINE PROTEASE - RATTUS NORVEGICUS (RAT).
O73800 SALMOBIN - GLOYDIUS HALYS (HALYS VIPER).
O74696 TRYPSIN-LIKE PROTEASE - PHAEOSPHAERIA NODORUM (SEPTORIA NODORUM).
O75754 MASP-2 PROTEIN PRECURSOR - HOMO SAPIENS (HUMAN).
O75837 SERINE PROTEASE (TLSP) - HOMO SAPIENS (HUMAN).
O76498 TRYPSIN PRECURSOR - DIAPREPES ABBREVIATUS (SUGARCANE ROOTSTALK BORER WEEVIL).
O76520 MIDGUT-SPECIFIC SERINE PROTEASE 2 - STOMOXYS CALCITRANS (STABLE FLY).
O76898 EG:80H7.1 PROTEIN - DROSOPHILA MELANOGASTER (FRUIT FLY).
O76920 EG:9D2.4 PROTEIN - DROSOPHILA MELANOGASTER (FRUIT FLY).
O76954 TRYPSIN PRECURSOR - LACANOBIA OLERACEA.
O77102 PROPHENOL OXIDASE ACTIVATING ENZYME PRECURSOR - MANDUCA SEXTA (TOBACCO HAWKMOTH) (TOBACCO HORNWORM).
O82261 F17A22.33 PROTEIN - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O83752 PERIPLASMIC SERINE PROTEASE DO (HTRA-1) - TREPONEMA PALLIDUM.
O87845 PUTATIVE SECRETED ESTERASE - STREPTOMYCES COELICOLOR.
O88301 SERINE PROTEASE (BSP) - MUS MUSCULUS (MOUSE).
O88309 PRORENIN-CONVERTING ENZYME (MK13B) PRECURSOR (MK13B) - MUS MUSCULUS (MOUSE).
O88780 NEUROPSIN PRECURSOR (EC 3.4.21.-) (NP) (BRAIN SERINE PROTEASE 1) - RATTUS NORVEGICUS (RAT).
O88947 COAGULATION FACTOR X PRECURSOR - MUS MUSCULUS (MOUSE).
O93265 TRYPSINOGEN 1 PRECURSOR (EC 3.4.21.4) - PLEURONECTES AMERICANUS.
O93266 TRYPSINOGEN 2 PRECURSOR (EC 3.4.21.4) - PLEURONECTES AMERICANUS.
O93502 SALMOBIN - GLOYDIUS HALYS (HALYS VIPER).
P70521 HEPATOCYTE GROWTH FACTOR-LIKE PROTEIN PRECURSOR (MACROPHAGE STIMULATORY PROTEIN) (MSP) - RATTUS NORVEGICUS (RAT).
P79204 PROTEASE-2 PRECURSOR - OVIS ARIES (SHEEP).
P79343 ACROSIN - BOS TAURUS (BOVINE).
P79816 BF/C2 PROTEIN - ORYZIAS LATIPES (MEDAKA FISH).
P79953 OVIDUCTIN - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
P91777 MASQUERADE-LIKE PROTEIN - PACIFASTACUS LENIUSCULUS (SIGNAL CRAYFISH).
P91817 LIMULUS FACTOR D - TACHYPLEUS TRIDENTATUS (JAPANESE HORSESHOE CRAB).
P91894 TRYPSIN-LIKE PROTEASE - ARENICOLA MARINA (LUGWORM) (ROCK WORM).
P97592 MAST CELL PROTEASE 4 PRECURSOR - RATTUS NORVEGICUS (RAT).
P97594 MAST CELL PROTEASE 8 PRECURSOR - RATTUS NORVEGICUS (RAT).
P97611 GRANZYME J - RATTUS NORVEGICUS (RAT).
PCE_TACTR PROCLOTTING ENZYME PRECURSOR (EC 3.4.21.86) - TACHYPLEUS TRIDENTATUS (JAPANESE HORSESHOE CRAB).
PLMN_BOVIN PLASMINOGEN PRECURSOR (EC 3.4.21.7) - BOS TAURUS (BOVINE).
PLMN_ERIEU PLASMINOGEN PRECURSOR (EC 3.4.21.7) - ERINACEUS EUROPAEUS (WESTERN EUROPEAN HEDGEHOG).
PLMN_HUMAN PLASMINOGEN PRECURSOR (EC 3.4.21.7) [CONTAINS: ANGIOSTATIN] - HOMO SAPIENS (HUMAN).
PLMN_MACMU PLASMINOGEN PRECURSOR (EC 3.4.21.7) - MACACA MULATTA (RHESUS MACAQUE).
PLMN_MOUSE PLASMINOGEN PRECURSOR (EC 3.4.21.7) [CONTAINS: ANGIOSTATIN] - MUS MUSCULUS (MOUSE).
PLMN_PIG PLASMINOGEN (EC 3.4.21.7) - SUS SCROFA (PIG).
PRN3_HUMAN MYELOBLASTIN PRECURSOR (EC 3.4.21.76) (LEUKOCYTE PROTEINASE 3) (PR-3) (PR3) (AGP7) (WEGENER'S AUTOANTIGEN) (P29) (C-ANCA ANTIGEN) - HOMO SAPIENS (HUMAN).
PROS_HUMAN PROSTATE SPECIFIC ANTIGEN PRECURSOR (EC 3.4.21.77) (PSA) (GAMMA- SEMINOPROTEIN) (SEMENOGELASE) (SEMININ) (P-30 ANTIGEN) - HOMO SAPIENS (HUMAN).
PROS_MACMU PROSTATE SPECIFIC ANTIGEN PRECURSOR (EC 3.4.21.35) (PSA) (GAMMA- SEMINOPROTEIN) - MACACA MULATTA (RHESUS MACAQUE).
PRTC_HUMAN VITAMIN-K DEPENDENT PROTEIN C PRECURSOR (EC 3.4.21.69) (AUTOPROTHROMBIN IIA) (ANTICOAGULANT PROTEIN C) (BLOOD COAGULATION FACTOR XIV) - HOMO SAPIENS (HUMAN).
PRTC_MOUSE VITAMIN-K DEPENDENT PROTEIN C PRECURSOR (EC 3.4.21.69) (AUTOPROTHROMBIN IIA) (ANTICOAGULANT PROTEIN C) (BLOOD COAGULATION FACTOR XIV) - MUS MUSCULUS (MOUSE).
PRTC_RAT VITAMIN-K DEPENDENT PROTEIN C PRECURSOR (EC 3.4.21.69) (AUTOPROTHROMBIN IIA) (ANTICOAGULANT PROTEIN C) (BLOOD COAGULATION FACTOR XIV) - RATTUS NORVEGICUS (RAT).
PSL1_HUMAN PROTEASE SERINE-LIKE 1 PRECURSOR (EC 3.4.21.-) (NORMAL EPITHELIAL CELL-SPECIFIC 1) - HOMO SAPIENS (HUMAN).
PSS8_HUMAN PROSTASIN PRECURSOR (EC 3.4.21.-) - HOMO SAPIENS (HUMAN).
PSS9_HUMAN PROTEASE M PRECURSOR (EC 3.4.21.-) (NEUROSIN) (ZYME) (SP59) - HOMO SAPIENS (HUMAN).
Q00344 ALP1 - COCHLIOBOLUS CARBONUM (BIPOLARIS ZEICOLA).
Q01136 TRYPSIN-LIKE PROTEASE 1 PRECURSOR - METARHIZIUM ANISOPLIAE.
Q03711 COMPLEMENT FACTOR I PRECURSOR (EC 3.4.21.45) (C3B/C4B INACTIVATOR) - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
Q10922 HYPOTHETICAL 174.3 KD PROTEIN B0286.2 IN CHROMOSOME II - CAENORHABDITIS ELEGANS.
Q13350 HEPATOCYTE GROWTH FACTOR-LIKE PROTEIN PRECURSOR (MACROPHAGE STIMULATORY PROTEIN) (MSP) (MACROPHAGE STIMULATING PROTEIN) - HOMO SAPIENS (HUMAN).
Q14243 PANCREATIC ELASTASE 2 PRECURSOR - HOMO SAPIENS (HUMAN).
Q14339 PREPROFACTOR VIIB PRECURSOR - HOMO SAPIENS (HUMAN).
Q14520 HGF ACTIVATOR LIKE PROTEIN - HOMO SAPIENS (HUMAN).
Q14870 MACROPHAGE-STIMULATING PROTEIN PRECURSOR - HOMO SAPIENS (HUMAN).
Q15146 PLASMINOGEN PRECURSOR - HOMO SAPIENS (HUMAN).
Q15661 TRYPTASE-I - HOMO SAPIENS (HUMAN).
Q15665 TRYPSINOGEN IV B-FORM - HOMO SAPIENS (HUMAN).
Q16618 UROKINASE PRECURSOR (EC 3.4.99.26) - HOMO SAPIENS (HUMAN).
Q17030 SERINE PROTEASE - ANOPHELES GAMBIAE (AFRICAN MALARIA MOSQUITO).
Q17086 ASTRYP1 - ANOPHELES STEPHENSI (INDO-PAKISTAN MALARIA MOSQUITO).
Q17800 SIMILAR TO PEPTIDASE FAMILY S1 - CAENORHABDITIS ELEGANS.
Q24019 MASQUERADE - DROSOPHILA MELANOGASTER (FRUIT FLY).
Q24091 TRYPSIN-LIKE PROTEASE (EC 3.4.21.-) (TRY29F) - DROSOPHILA MELANOGASTER (FRUIT FLY).
Q25081 SERINE PROTEASE - HYPODERMA LINEATUM (EARLY CATTLE GRUB) (COMMON CATTLE GRUB).
Q25082 SERINE PROTEASE - HYPODERMA LINEATUM (EARLY CATTLE GRUB) (COMMON CATTLE GRUB).
Q25101 SERINE PROTEINASE - HERDMANIA MOMUS.
Q25227 CHYMOTRYPSINOGEN PRECURSOR - LUCILIA CUPRINA (GREENBOTTLE FLY) (AUSTRALIAN SHEEP BLOWFLY).
Q25503 CHYMOTRYPSINOGEN PRECURSOR - MANDUCA SEXTA (TOBACCO HAWKMOTH) (TOBACCO HORNWORM).
Q25510 ELASTASE PRECURSOR - MANDUCA SEXTA (TOBACCO HAWKMOTH) (TOBACCO HORNWORM).
Q26422 FACTOR C - CARCINOSCORPIUS ROTUNDICAUDA (SOUTHEAST ASIAN HORSESHOE CRAB).
Q26423 FACTOR C - CARCINOSCORPIUS ROTUNDICAUDA (SOUTHEAST ASIAN HORSESHOE CRAB).
Q26552 ELASTASE - SCHISTOSOMA MANSONI (BLOOD FLUKE).
Q27081 HORSESHOE CRAB COAGULATION FACTOR B PRECURSOR - TACHYPLEUS TRIDENTATUS (JAPANESE HORSESHOE CRAB).
Q27083 CLOTTING FACTOR G BETA SUBUNIT PRECURSOR - TACHYPLEUS TRIDENTATUS (JAPANESE HORSESHOE CRAB).
Q27440 TRYPSIN PRECURSOR (EC 3.4.21.4) (ALPHA- AND BETA-TRYPSIN) - AEDES AEGYPTI (YELLOWFEVER MOSQUITO).
Q27444 CHYMOTRYPSINOGEN PRECURSOR (EC 3.4.21.1) (CHYMOTRYPSIN A) (CHYMOTRYPSIN B) (ALPHA-CHYMOTRYPSIN) - ARENICOLA MARINA (LUGWORM) (ROCK WORM).
Q27458 SERINE PROTEASE (EC 3.4.21.1) (CHYMOTRYPSIN) (CHYMOTRYPSIN A) (CHYMOTRYPSIN B) (ALPHA-CHYMOTRYPSIN) - BOTRYLLUS SCHLOSSERI.
Q27540 TRYPSIN (EC 3.4.21.4) (ALPHA- AND BETA-TRYPSIN) - CHORISTONEURA FUMIFERANA (SPRUCE BUDWORM).
Q27761 TRYPSIN PRECURSOR (EC 3.4.21.4) (ALPHA- AND BETA-TRYPSIN) - PENAEUS VANNAMEI (PENOEID SHRIMP) (EUROPEAN WHITE SHRIMP).
Q27824 SERINE COLLAGENASE 1 PRECURSOR (EC 3.4.21.32) (BRACHYURIN) (COLLAGENOLYTIC PROTEASE) - UCA PUGILATOR (ATLANTIC SAND FIDDLER CRAB) (CELUCA PUGILATOR).
Q29015 PREPROACROSIN - SUS SCROFA (PIG).
Q29474 KALLIKREIN PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) (GLANDULAR KALLIKREIN) (KININOGENIN) - CANIS FAMILIARIS (DOG).
Q31430 COMPLEMENT FACTOR B - LAMPETRA JAPONICA (JAPANESE LAMPREY).
Q40953 SERINE PROTEASE-LIKE PROTEIN PRECURSOR - PORPHYRA PURPUREA.
Q54137 TRYPSIN-LIKE PROTEASE - SACCHAROPOLYSPORA ERYTHRAEA (STREPTOMYCES ERYTHRAEUS).
Q54165 SEPA GENE PRECURSOR - SHIGELLA FLEXNERI.
Q54168 TRYPSINOGEN PRECURSOR - STREPTOMYCES FRADIAE.
Q54213 SERINE PROTEASE - STREPTOMYCES GRISEUS.
Q54344 ESTERASE PRECURSOR - STREPTOMYCES LIVIDANS.
Q54345 ESTERASE PRECURSOR - STREPTOMYCES LIVIDANS.
Q60574 HAPTOGLOBIN - MUS CAROLI (WILD MOUSE) (RICEFIELD MOUSE).
Q61109 COAGULATION FACTOR VII - MUS MUSCULUS (MOUSE).
Q61129 COMPLEMENT COMPONENT FACTOR I (COMPLEMENT FACTOR I) - MUS MUSCULUS (MOUSE).
Q61388 CYTOTOXIC CELL PROTEINASE 5 - MUS MUSCULUS (MOUSE).
Q61515 NEUTROPHIL ELASTASE - MUS MUSCULUS (MOUSE).
Q61646 HAPTOGLOBIN - MUS MUSCULUS (MOUSE).
Q61855 TISSUE KALLIKREIN - MUS MUSCULUS (MOUSE).
Q61955 NEUROPSIN PRECURSOR (EC 3.4.21.-) (NP) - MUS MUSCULUS (MOUSE).
Q63207 FACTOR X - RATTUS NORVEGICUS (RAT).
Q63224 GRANZYME-LIKE PROTEIN III - RATTUS NORVEGICUS (RAT).
Q63636 NATURAL KILLER CELL PROTEASE 4 - RATTUS NORVEGICUS (RAT).
Q63637 NATURAL KILLER CELL PROTEASE 7 - RATTUS NORVEGICUS (RAT).
Q64007 HEPATOCYTE GROWTH FACTOR - MUS MUSCULUS (MOUSE).
Q90422 COMPLEMENT FACTOR B PRECURSOR - BRACHYDANIO RERIO (ZEBRAFISH) (ZEBRA DANIO).
Q90504 THROMBIN - EPTATRETUS STOUTII (PACIFIC HAGFISH).
Q90865 HEPATOCYTE GROWTH FACTOR-LIKE/MACROPHAGE STIMULATING PROTEIN - GALLUS GALLUS (CHICKEN).
Q90978 HEPATOCYTE GROWTH FACTOR PRECURSOR (SCATTER FACTOR) (SF) (HEPATOPOEITIN A) (HGF/SF) - GALLUS GALLUS (CHICKEN).
Q91001 THROMBIN - GALLUS GALLUS (CHICKEN).
Q91039 ELASTASE A PRECURSOR - GADUS MORHUA (ATLANTIC COD).
Q91053 CALOBIN - GLOYDIUS USSURIENSIS.
Q91500 PREPROTRIMUBIN PRECURSOR - TRIMERESURUS MUCROSQUAMATUS (TAIWAN HABU).
Q91507 MUCOFIRASE 1 - TRIMERESURUS MUCROSQUAMATUS (TAIWAN HABU).
Q91508 MUCOFIRASE 2 - TRIMERESURUS MUCROSQUAMATUS (TAIWAN HABU).
Q91509 MUCOFIRASE 3 - TRIMERESURUS MUCROSQUAMATUS (TAIWAN HABU).
Q91510 MUCOFIRASE 4 - TRIMERESURUS MUCROSQUAMATUS (TAIWAN HABU).
Q91511 MUCOFIRASE 5 - TRIMERESURUS MUCROSQUAMATUS (TAIWAN HABU).
Q91516 VENOM PLASMINOGEN ACTIVATOR PRECURSOR - TRIMERESURUS STEJNEGERI (CHINESE GREEN TREE VIPER).
Q91674 POLYPROTEIN (OVOCHYMASE) - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
Q91701 XENOPUS BF B - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
Q91900 COMPLEMENT FACTOR B - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
Q92046 PREPROTRYPSIN PRECURSOR (EC 3.4.21.4) (ALPHA- AND BETA-TRYPSIN) - DISSOSTICHUS MAWSONI.
Q92077 ELASTASE PRECURSOR (EC 3.4.21.37) (LEUKOCYTE ELASTASE) (LYSOSOMAL ELASTASE) (NEUTROPHIL ELASTASE) (BONE MARROW SERINE PROTEASE) (MEDULLASIN) - GADUS MORHUA (ATLANTIC COD).
Q92099 TRYPSIN PRECURSOR (EC 3.4.21.4) (ALPHA- AND BETA-TRYPSIN) - PARANOTOTHENIA MAGELLANICA.
Q92658 HAPTOGLOBIN - HOMO SAPIENS (HUMAN).
Q92659 HAPTOGLOBIN-RELATED PROTEIN - HOMO SAPIENS (HUMAN).
Q92743 NOVEL SERINE PROTEASE - HOMO SAPIENS (HUMAN).
Q94176 SIMILAR TO PEPTIDASE FAMILY S1 - CAENORHABDITIS ELEGANS.
RVVA_DABRU VIPERA RUSSELLI PROTEINASE RVV-V ALPHA (EC 3.4.21.95) (FACTOR V- ACTIVATING PROTEINASE ALPHA) (SNAKE VENOM FACTOR V ACTIVATOR ALPHA) - DABOIA RUSSELLI SIAMENSIS (SIAMESE RUSSELL'S VIPER) (VIPERA RUSSELLI SIAMENSIS).
RVVG_DABRU VIPERA RUSSELLI PROTEINASE RVV-V GAMMA (EC 3.4.21.95) (FACTOR V- ACTIVATING PROTEINASE GAMMA) (SNAKE VENOM FACTOR V ACTIVATOR GAMMA) - DABOIA RUSSELLI SIAMENSIS (SIAMESE RUSSELL'S VIPER) (VIPERA RUSSELLI SIAMENSIS).
S24D_ANOGA SERINE PROTEASE SP24D PRECURSOR (EC 3.4.21.-) (AGSP24D) - ANOPHELES GAMBIAE (AFRICAN MALARIA MOSQUITO).
SCCE_HUMAN STRATUM CORNEUM CHYMOTRYPTIC ENZYME PRECURSOR (EC 3.4.21.-) (SCCE) - HOMO SAPIENS (HUMAN).
SER1_DROME SERINE PROTEASES 1 AND 2 PRECURSOR (EC 3.4.21.-) - DROSOPHILA MELANOGASTER (FRUIT FLY).
SNAK_DROME SERINE PROTEASE SNAKE PRECURSOR (EC 3.4.21.-) - DROSOPHILA MELANOGASTER (FRUIT FLY).
STUB_DROME SERINE PROTEINASE STUBBLE (EC 3.4.21.-) (STUBBLE-STUBBLOID PROTEIN) - DROSOPHILA MELANOGASTER (FRUIT FLY).
THRB_BOVIN PROTHROMBIN PRECURSOR (EC 3.4.21.5) - BOS TAURUS (BOVINE).
THRB_HUMAN PROTHROMBIN PRECURSOR (EC 3.4.21.5) (COAGULATION FACTOR II) - HOMO SAPIENS (HUMA
THRB_MOUSE PROTHROMBIN PRECURSOR (EC 3.4.21.5) - MUS MUSCULUS (MOUSE).
THRB_RAT PROTHROMBIN PRECURSOR (EC 3.4.21.5) - RATTUS NORVEGICUS (RAT).
TMS2_HUMAN TRANSMEMBRANE PROTEASE, SERINE 2 (EC 3.4.21.-) - HOMO SAPIENS (HUMAN).
TRY1_ANOGA TRYPSIN 1 PRECURSOR (EC 3.4.21.4) - ANOPHELES GAMBIAE (AFRICAN MALARIA MOSQUITO).
TRY1_CANFA TRYPSINOGEN, CATIONIC PRECURSOR (EC 3.4.21.4) - CANIS FAMILIARIS (DOG).
TRY1_CHICK TRYPSINOGEN I-P1 PRECURSOR - GALLUS GALLUS (CHICKEN).
TRY1_GADMO TRYPSINOGEN I PRECURSOR (EC 3.4.21.4) - GADUS MORHUA (ATLANTIC COD).
TRY1_HUMAN TRYPSINOGEN I PRECURSOR (EC 3.4.21.4) (CATIONIC TRYPSINOGEN) - HOMO SAPIENS (HUMAN).
TRY1_RAT TRYPSINOGEN I, ANIONIC PRECURSOR (EC 3.4.21.4) (PRETRYPSINOGEN I) - RATTUS NORVEGICUS (RAT).
TRY1_SALSA TRYPSINOGEN I PRECURSOR (EC 3.4.21.4) - SALMO SALAR (ATLANTIC SALMON).
TRY1_XENLA TRYPSIN PRECURSOR (EC 3.4.21.4) - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
TRY2_ANOGA TRYPSIN 2 PRECURSOR (EC 3.4.21.4) - ANOPHELES GAMBIAE (AFRICAN MALARIA MOSQUITO).
TRY2_BOVIN TRYPSINOGEN, ANIONIC PRECURSOR (EC 3.4.21.4) - BOS TAURUS (BOVINE).
TRY2_CANFA TRYPSINOGEN, ANIONIC PRECURSOR (EC 3.4.21.4) - CANIS FAMILIARIS (DOG).
TRY2_CHICK TRYPSINOGEN I-P38 PRECURSOR - GALLUS GALLUS (CHICKEN).
TRY2_HUMAN TRYPSINOGEN II PRECURSOR (EC 3.4.21.4) (ANIONIC TRYPSINOGEN) - HOMO SAPIENS (HUMAN).
TRY2_RAT TRYPSINOGEN II, ANIONIC PRECURSOR (EC 3.4.21.4) (PRETRYPSINOGEN II) - RATTUS NORVEGICUS (RAT).
TRY2_XENLA TRYPSINOGEN PRECURSOR - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
TRY3_AEDAE TRYPSIN 3A1 PRECURSOR (EC 3.4.21.4) - AEDES AEGYPTI (YELLOWFEVER MOSQUITO).
TRY3_ANOGA TRYPSIN 3 PRECURSOR (EC 3.4.21.4) - ANOPHELES GAMBIAE (AFRICAN MALARIA MOSQUITO).
TRY3_CHICK TRYPSINOGEN II-P29 PRECURSOR - GALLUS GALLUS (CHICKEN).
TRY3_HUMAN TRYPSINOGEN III PRECURSOR (EC 3.4.21.4) - HOMO SAPIENS (HUMAN).
TRY3_RAT TRYPSINOGEN III, CATIONIC PRECURSOR (EC 3.4.21.4) (PRETRYPSINOGEN III) - RATTUS NORVEGICUS (RAT).
TRY4_ANOGA TRYPSIN 4 PRECURSOR (EC 3.4.21.4) - ANOPHELES GAMBIAE (AFRICAN MALARIA MOSQUITO).
TRY4_HUMAN TRYPSINOGEN IVA PRECURSOR (EC 3.4.21.4) - HOMO SAPIENS (HUMAN).
TRY4_LUCCU TRYPSIN ALPHA-4 PRECURSOR (EC 3.4.21.4) - LUCILIA CUPRINA (GREENBOTTLE FLY) (AUSTRALIAN SHEEP BLOWFLY).
TRY4_RAT TRYPSINOGEN IV PRECURSOR (EC 3.4.21.4) (PRETRYPSINOGEN IV) - RATTUS NORVEGICUS (RAT).
TRY5_ANOGA TRYPSIN 5 PRECURSOR (EC 3.4.21.4) - ANOPHELES GAMBIAE (AFRICAN MALARIA MOSQUITO).
TRY6_ANOGA TRYPSIN 6 PRECURSOR (EC 3.4.21.4) - ANOPHELES GAMBIAE (AFRICAN MALARIA MOSQUITO).
TRY7_ANOGA TRYPSIN 7 PRECURSOR (EC 3.4.21.4) - ANOPHELES GAMBIAE (AFRICAN MALARIA MOSQUITO).
TRYA_DROER TRYPSIN ALPHA PRECURSOR (EC 3.4.21.4) - DROSOPHILA ERECTA (FRUIT FLY).
TRYA_DROME TRYPSIN ALPHA PRECURSOR (EC 3.4.21.4) - DROSOPHILA MELANOGASTER (FRUIT FLY).
TRYA_HUMAN ALPHA-TRYPTASE PRECURSOR (EC 3.4.21.59) (TRYPTASE 1) - HOMO SAPIENS (HUMAN).
TRYA_MANSE TRYPSIN, ALKALINE A PRECURSOR - MANDUCA SEXTA (TOBACCO HAWKMOTH) (TOBACCO HORNWORM).
TRYA_RAT TRYPSINOGEN V-A PRECURSOR (EC 3.4.21.4) - RATTUS NORVEGICUS (RAT).
TRYB_DROER TRYPSIN BETA PRECURSOR (EC 3.4.21.4) - DROSOPHILA ERECTA (FRUIT FLY).
TRYB_DROME TRYPSIN BETA PRECURSOR (EC 3.4.21.4) - DROSOPHILA MELANOGASTER (FRUIT FLY).
TRYB_HUMAN BETA-TRYPTASE PRECURSOR (EC 3.4.21.59) (TRYPTASE 2) - HOMO SAPIENS (HUMAN).
TRYB_MANSE TRYPSIN, ALKALINE B PRECURSOR - MANDUCA SEXTA (TOBACCO HAWKMOTH) (TOBACCO HORNWORM).
TRYB_RAT TRYPSINOGEN V-B PRECURSOR (EC 3.4.21.4) - RATTUS NORVEGICUS (RAT).
TRYC_MANSE TRYPSIN, ALKALINE C PRECURSOR - MANDUCA SEXTA (TOBACCO HAWKMOTH) (TOBACCO HORNWORM).
TRYD_DROER TRYPSIN DELTA/GAMMA PRECURSOR (EC 3.4.21.4) - DROSOPHILA ERECTA (FRUIT FLY).
TRYD_DROME TRYPSIN DELTA PRECURSOR (EC 3.4.21.4) - DROSOPHILA MELANOGASTER (FRUIT FLY).
TRYE_DROER TRYPSIN EPSILON PRECURSOR (EC 3.4.21.4) - DROSOPHILA ERECTA (FRUIT FLY).
TRYE_DROME TRYPSIN EPSILON PRECURSOR (EC 3.4.21.4) - DROSOPHILA MELANOGASTER (FRUIT FLY).
TRYG_DROME TRYPSIN GAMMA PRECURSOR (EC 3.4.21.4) - DROSOPHILA MELANOGASTER (FRUIT FLY).
TRYI_DROME TRYPSIN IOTA PRECURSOR (EC 3.4.21.4) - DROSOPHILA MELANOGASTER (FRUIT FLY).
TRYM_CANFA MASTOCYTOMA PROTEASE PRECURSOR (EC 3.4.21.-) - CANIS FAMILIARIS (DOG).
TRYM_RAT MAST CELL TRYPTASE PRECURSOR (EC 3.4.21.59) (MAST CELL PROTEASE 6) (RMCP-6) - RATTUS NORVEGICUS (RAT).
TRYP_ASTFL TRYPSIN I (EC 3.4.21.4) - ASTACUS FLUVIATILIS (BROAD-FINGERED CRAYFISH) (ASTACUS ASTACUS).
TRYP_CHOFU TRYPSIN CFT-1 PRECURSOR (EC 3.4.21.4) - CHORISTONEURA FUMIFERANA (SPRUCE BUDWORM).
TRYP_FUSOX TRYPSIN PRECURSOR (EC 3.4.21.4) - FUSARIUM OXYSPORUM.
TRYP_MOUSE TRYPSINOGEN PRECURSOR (EC 3.4.21.4) - MUS MUSCULUS (MOUSE).
TRYP_PIG TRYPSIN PRECURSOR (EC 3.4.21.4) - SUS SCROFA (PIG).
TRYP_SACER TRYPSIN (EC 3.4.21.4) (SET) - SACCHAROPOLYSPORA ERYTHRAEA (STREPTOMYCES ERYTHRAEUS).
TRYP_SARBU TRYPSIN PRECURSOR (EC 3.4.21.4) - SARCOPHAGA BULLATA (GREY FLESH FLY) (NEOBELLIERIA BULLATA).
TRYP_SQUAC TRYPSIN PRECURSOR (EC 3.4.21.4) - SQUALUS ACANTHIAS (SPINY DOGFISH).
TRYP_STRGA TRYPSIN-LIKE PROTEASE PRECURSOR (EC 3.4.21.-) - STREPTOMYCES GLAUCESCENS.
TRYP_STRGR TRYPSIN PRECURSOR (EC 3.4.21.4) (SGT) - STREPTOMYCES GRISEUS.
TRYT_CANFA TRYPTASE PRECURSOR (EC 3.4.21.59) - CANIS FAMILIARIS (DOG).
TRYT_DROER TRYPSIN THETA PRECURSOR (EC 3.4.21.4) - DROSOPHILA ERECTA (FRUIT FLY).
TRYT_DROME TRYPSIN THETA PRECURSOR (EC 3.4.21.4) - DROSOPHILA MELANOGASTER (FRUIT FLY).
TRYT_MERUN MAST CELL TRYPTASE PRECURSOR (EC 3.4.21.59) - MERIONES UNGUICULATUS (MONGOLIAN JIRD).
TRYU_DROER TRYPSIN ETA PRECURSOR (EC 3.4.21.4) - DROSOPHILA ERECTA (FRUIT FLY).
TRYU_DROME TRYPSIN ETA PRECURSOR (EC 3.4.21.4) - DROSOPHILA MELANOGASTER (FRUIT FLY).
TRYX_GADMO TRYPSINOGEN X PRECURSOR (EC 3.4.21.4) - GADUS MORHUA (ATLANTIC COD).
TRYZ_DROER TRYPSIN ZETA PRECURSOR (EC 3.4.21.4) - DROSOPHILA ERECTA (FRUIT FLY).
TRYZ_DROME TRYPSIN ZETA PRECURSOR (EC 3.4.21.4) - DROSOPHILA MELANOGASTER (FRUIT FLY).
UROK_BOVIN UROKINASE-TYPE PLASMINOGEN ACTIVATOR PRECURSOR (EC 3.4.21.73) (UPA) (U-PLASMINOGEN ACTIVATOR) - BOS TAURUS (BOVINE).
UROK_CHICK UROKINASE-TYPE PLASMINOGEN ACTIVATOR PRECURSOR (EC 3.4.21.73) (UPA) (U-PLASMINOGEN ACTIVATOR) - GALLUS GALLUS (CHICKEN).
UROK_HUMAN UROKINASE-TYPE PLASMINOGEN ACTIVATOR PRECURSOR (EC 3.4.21.73) (UPA) (U-PLASMINOGEN ACTIVATOR) - HOMO SAPIENS (HUMAN).
UROK_MOUSE UROKINASE-TYPE PLASMINOGEN ACTIVATOR PRECURSOR (EC 3.4.21.73) (UPA) (U-PLASMINOGEN ACTIVATOR) - MUS MUSCULUS (MOUSE).
UROK_PAPCY UROKINASE-TYPE PLASMINOGEN ACTIVATOR PRECURSOR (EC 3.4.21.73) (UPA) (U-PLASMINOGEN ACTIVATOR) - PAPIO CYNOCEPHALUS (YELLOW BABOON).
UROK_PIG UROKINASE-TYPE PLASMINOGEN ACTIVATOR PRECURSOR (EC 3.4.21.73) (UPA) (U-PLASMINOGEN ACTIVATOR) - SUS SCROFA (PIG).
UROK_RAT UROKINASE-TYPE PLASMINOGEN ACTIVATOR PRECURSOR (EC 3.4.21.73) (UPA) (U-PLASMINOGEN ACTIVATOR) - RATTUS NORVEGICUS (RAT).
UROT_BOVIN TISSUE PLASMINOGEN ACTIVATOR PRECURSOR (EC 3.4.21.68) (TPA) (T-PLASMINOGEN ACTIVATOR) - BOS TAURUS (BOVINE).
UROT_HUMAN TISSUE PLASMINOGEN ACTIVATOR PRECURSOR (EC 3.4.21.68) (TPA) (T-PLASMINOGEN ACTIVATOR) (ALTEPLASE) (RETEPLASE) - HOMO SAPIENS (HUMAN).
UROT_MOUSE TISSUE PLASMINOGEN ACTIVATOR PRECURSOR (EC 3.4.21.68) (TPA) (T-PLASMINOGEN ACTIVATOR) - MUS MUSCULUS (MOUSE).
UROT_RAT TISSUE PLASMINOGEN ACTIVATOR PRECURSOR (EC 3.4.21.68) (TPA) (T-PLASMINOGEN ACTIVATOR) - RATTUS NORVEGICUS (RAT).
URT1_DESRO SALIVARY PLASMINOGEN ACTIVATOR ALPHA 1 PRECURSOR (EC 3.4.21.68) (DSPA ALPHA-1) - DESMODUS ROTUNDUS (VAMPIRE BAT).
URT2_DESRO SALIVARY PLASMINOGEN ACTIVATOR ALPHA 2 PRECURSOR (EC 3.4.21.68) (DSPA ALPHA-2) (BAT-PA) (T-PLASMINOGEN ACTIVATOR) - DESMODUS ROTUNDUS (VAMPIRE BAT).
URTB_DESRO SALIVARY PLASMINOGEN ACTIVATOR BETA PRECURSOR (EC 3.4.21.68) (DSPA BETA) - DESMODUS ROTUNDUS (VAMPIRE BAT).
URTG_DESRO SALIVARY PLASMINOGEN ACTIVATOR GAMMA PRECURSOR (EC 3.4.21.68) (DSPA GAMMA) - DESMODUS ROTUNDUS (VAMPIRE BAT).
VDP_BOMMO VITELLIN-DEGRADING PROTEASE PRECURSOR (EC 3.4.21.-) [CONTAINS: ALPHA-VTN PROTEASE; BETA-VTN PROTEASE] - BOMBYX MORI (SILK MOTH).
DEGQ_ECOLI PROTEASE DEGQ PRECURSOR (EC 3.4.21.-) - ESCHERICHIA COLI.
DNBI_HCMVA MAJOR DNA-BINDING PROTEIN (MDBP) - HUMAN CYTOMEGALOVIRUS (STRAIN AD169).
ETA_STAAU Exfoliative toxin A precursor (EC 3.4.21.-) (Epidermolytic toxin A) - Staphylococcus aureus.
GILX_HELHO GILATOXIN (EC 3.4.21.-) - HELODERMA HORRIDUM HORRIDUM (MEXICAN BEADED LIZARD).
GSEP_BACLI GLUTAMYL ENDOPEPTIDASE PRECURSOR (EC 3.4.21.19) (GLUTAMATE SPECIFIC ENDOPEPTIDASE) (GSE) - BACILLUS LICHENIFORMIS.
HTOA_HAEIN PROBABLE PERIPLASMIC SERINE PROTEASE DO/HHOA-LIKE PRECURSOR - HAEMOPHILUS INFLUENZAE.
HTRA_ECOLI PROTEASE DO PRECURSOR (EC 3.4.21.-) - ESCHERICHIA COLI.
HTRA_SALTY PROTEASE DO PRECURSOR (EC 3.4.21.-) - SALMONELLA TYPHIMURIUM.
IGA0_HAEIN IMMUNOGLOBULIN A1 PROTEASE PRECURSOR (EC 3.4.21.72) (IGA1 PROTEASE) - HAEMOPHILUS INFLUENZAE.
IGA1_HAEIN IMMUNOGLOBULIN A1 PROTEASE PRECURSOR (EC 3.4.21.72) (IGA1 PROTEASE) - HAEMOPHILUS INFLUENZAE.
IGA2_HAEIN IMMUNOGLOBULIN A1 PROTEASE PRECURSOR (EC 3.4.21.72) (IGA1 PROTEASE) - HAEMOPHILUS INFLUENZAE.
O01655 ASMASPB - HALOCYNTHIA RORETZI (SEA SQUIRT).
O01771 SIMILAR TO THE S1 FAMILY OF PEPTIDASES - CAENORHABDITIS ELEGANS.
O01953 SERINE PROTEASE PRECURSOR - BOMBYX MORI (SILK MOTH).
O04480 F5I14.16 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O04481 SIMILARITY TO F5I14.16 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O04674 HTRA-LIKE PROTEIN - HAEMATOCOCCUS PLUVIALIS.
O06439 FDXE GENE - RHODOBACTER CAPSULATUS (RHODOPSEUDOMONAS CAPSULATA).
O16101 SERINE PROTEASE SER4 PRECURSOR - DROSOPHILA MELANOGASTER (FRUIT FLY).
O18441 TRYPSIN-LIKE PROTEASE PRECURSOR - HELICOVERPA ARMIGERA (COTTON BOLLWORM).
O18442 TRYPSIN-LIKE PROTEASE PRECURSOR - HELICOVERPA ARMIGERA (COTTON BOLLWORM).
O18457 SERINE PROTEINASE PRECURSOR - HETERODERA GLYCINES.
O18458 SERINE PROTEINASE PRECURSOR - HETERODERA GLYCINES.
O18655 CHYMOTRYPSINOGEN-LIKE PROTEIN - PLODIA INTERPUNCTELLA (INDIAN MEAL MOTH).
O31686 YKVU PROTEIN - BACILLUS SUBTILIS.
O43464 SERINE PROTEASE - HOMO SAPIENS (HUMAN).
O45421 F31D4.6 PROTEIN - CAENORHABDITIS ELEGANS.
O46137 CHYMOTRYSIN PRECURSOR - LUMBRICUS RUBELLUS (HUMUS EARTHWORM).
O49507 HYPOTHETICAL 92.1 KD PROTEIN - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O51131 PERIPLASMIC SERINE PROTEASE DO (HTRA) - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
O53896 PUTATIVE SERINE PROTEASE - MYCOBACTERIUM TUBERCULOSIS.
O62589 SERINE PROTEASE (EC 3.4.21.-) (GASTRULATION DEFECTIVE PROTEIN) (GD) - DROSOPHILA MELANOGASTER (FRUIT FLY).
O62598 TRYPSIN - PLODIA INTERPUNCTELLA (INDIAN MEAL MOTH).
O68198 HTRA - HAEMOPHILUS INFLUENZAE.
O69639 SERINE PROTEASE - MYCOBACTERIUM TUBERCULOSIS.
O76519 MIDGUT-SPECIFIC SERINE PROTEASE 1 - STOMOXYS CALCITRANS (STABLE FLY).
O76652 F25E5.4 PROTEIN - CAENORHABDITIS ELEGANS.
O76900 EG:80H7.3 PROTEIN - DROSOPHILA MELANOGASTER (FRUIT FLY).
O84502 ADP/ATP TRANSLOCASE - CHLAMYDIA TRACHOMATIS.
O85291 PERIPLASMIC SERINE PROTEASE - BUCHNERA APHIDICOLA.
O89278 NONSTRUCTURAL PROTEIN PRECURSOR - HIMETOBI P VIRUS.
P70006 HEPATOCYTE GROWTH FACTOR-LIKE PROTEIN PRECURSOR - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
P72780 PROTEASE HHOA - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
P73354 SERINE PROTEASE HTRA - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
P73940 PROTEASE HHOB - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
P74978 GSRA PROTEIN - YERSINIA ENTEROCOLITICA.
P76176 FROM BASES 1663181 TO 1676139 (SECTION 145 OF 400) OF THE COMPLETE GENOME (SECTION 145 OF 400) - ESCHERICHIA COLI.
P96358 HYPOTHETICAL 36.1 KD PROTEIN - MYCOBACTERIUM TUBERCULOSIS.
POLG_DEN2J GENOME POLYPROTEIN [CONTAINS: CAPSID PROTEIN C (CORE PROTEIN); MATRIX PROTEIN (ENVELOPE GLYCOPROTEIN M); MAJOR ENVELOPE PROTEIN E; NONSTRUCTURAL PROTEINS NS1, NS2A, NS2B, NS4A AND NS4B; HELICASE (NS3); RNA-DIRECTED RNA POLYMERASE (EC 2.7.7.48) (NS5)] - DENGUE VIRUS TYPE 2 (STRAIN JAMAICA).
POLG_DEN2P GENOME POLYPROTEIN [CONTAINS: CAPSID PROTEIN C (CORE PROTEIN); MATRIX PROTEIN (ENVELOPE GLYCOPROTEIN M); MAJOR ENVELOPE PROTEIN E; NONSTRUCTURAL PROTEINS NS1, NS2A, NS2B, NS4A AND NS4B; HELICASE (NS3); RNA-DIRECTED RNA POLYMERASE (EC 2.7.7.48) (NS5)] - DENGUE VIRUS TYPE 2 (STRAIN PR159/S1).
PRTA_STRGR STREPTOGRISIN A PRECURSOR (EC 3.4.21.80) (PROTEASE A) (SGPA) (PRONASE ENZYME A) - STREPTOMYCES GRISEUS.
PRTZ_BOVIN VITAMIN K-DEPENDENT PROTEIN Z - BOS TAURUS (BOVINE).
PRTZ_HUMAN VITAMIN K-DEPENDENT PROTEIN Z PRECURSOR - HOMO SAPIENS (HUMAN).
Q07277 KALLIKREIN PRECURSOR (EC 3.4.21.35) (TISSUE KALLIKREIN) - HOMO SAPIENS (HUMAN).
Q13208 HEPATOCYTE GROWTH FACTOR-LIKE PROTEIN HOMOLOG (D1F15S1A) - HOMO SAPIENS (HUMAN).
Q15213 PROTEIN Z PRECURSOR - HOMO SAPIENS (HUMAN).
Q15946 GLANDULAR KALLIKREIN-1 PROTEIN - HOMO SAPIENS (HUMAN).
Q16900 CHYMOTRYPSIN-LIKE PROTEASE PRECURSOR - AEDES AEGYPTI (YELLOWFEVER MOSQUITO).
Q23528 SIMILAR TO PLASMINOGEN AND TO TRYPSIN-LIKE SERINE PROTEASES - CAENORHABDITIS ELEGANS.
Q25394 LUMBROKINASE-1T4 PRECURSOR - LUMBRICUS RUBELLUS (HUMUS EARTHWORM).
Q25395 LUMBROKINASE-3(1) PRECURSOR - LUMBRICUS RUBELLUS (HUMUS EARTHWORM).
Q26553 ELASTASE - SCHISTOSOMA MANSONI (BLOOD FLUKE).
Q26912 PROTEIN 1 OF A DISPERSED GENE FAMILY (DGF-1) - TRYPANOSOMA CRUZI.
Q28609 PUTATIVE PREPROSPERMINOGEN PRECURSOR - ORYCTOLAGUS CUNICULUS (RABBIT).
Q50320 34KDA PROTEIN PRECURSOR - MYCOBACTERIUM PARATUBERCULOSIS.
Q52423 ENDO ALPHA-1,4 POLYGALACTOSAMINIDASE PRECUSOR PRECURSOR - PSEUDOMONAS SP.
Q53756 SAM-P20 SERINE PROTEASE PRECURSOR - STREPTOMYCES ALBOGRISEOLUS.
Q54392 PROTEASE - STREPTOMYCES LIVIDANS.
Q65538 GB GLYCOPROTEIN - BABOON HERPESVIRUS 2.
Q65540 GB GLYCOPROTEIN - BABOON HERPESVIRUS 2.
Q91691 GROWTH FACTOR LIVERTINE - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
RLPB_ECOLI RARE LIPOPROTEIN B PRECURSOR - ESCHERICHIA COLI.
RPOA_LELV POL POLYPROTEIN (ORF1A/1B) [CONTAINS: RNA-DIRECTED RNA POLYMERASE (EC 2.7.7.48); HELICASE; PROTEASE (EC 3.4.21.-)] - LELYSTAD VIRUS (LV) (PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS).
SFA2_STRFR SERINE PROTEASE 2 (EC 3.4.21.-) (SFASE-2) - STREPTOMYCES FRADIAE.
THRL_LACMU GYROXIN ANALOG (EC 3.4.21.74) (THROMBIN-LIKE ENZYME) (VENOMBIN A) - LACHESIS MUTA MUTA (BUSHMASTER).
TRYP_PLEPL TRYPSIN PRECURSOR (EC 3.4.21.4) - PLEURONECTES PLATESSA (PLAICE).
Y4BJ_RHISN HYPOTHETICAL 67.9 KD PROTEIN Y4BJ - RHIZOBIUM SP. (STRAIN NGR234).
|