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PR00678

Identifier
PI3KINASEP85  [View Relations]  [View Alignment]  
Accession
PR00678
No. of Motifs
10
Creation Date
07-FEB-1997  (UPDATE 10-JUN-1999)
Title
PI3 kinase P85 regulatory subunit signature
Database References

INTERPRO; IPR001720
Literature References
1. COURTNEIDGE, S.A., DHAND, R., FRY, M.J., GOUT, I., HILES, I., ET AL..
Characterization of two 85 kd proteins that associate with receptor
tyrosine kinases, and PI3-Kinase.   
CELL 65(1) 91-104 (1991).
 
2. ESCOBEDO, J.A., FRIED, V.A., KAVANAUGH, W.M., ET AL..
cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates
binding of PI3-Kinase to the PDGF beta-receptor.
CELL 65(1) 75-82 (1991).

Documentation
PI3 kinases are enzymes that phosphorylate phosphoinositides on the
3-hydroxyl group of the inositol ring. The precise functions of the three
products of PI3 kinase (PI-3-P, PI-3,4-P and PI-3,4,5-P) are not yet
known, but it is suggested that they function as second messengers in
signal transduction events in organisms ranging from yeast to mammals.
There are several forms of PI3 kinase. One of these is the mammalian enzyme, 
a heterodimer of a 110kd catalytic subunit and an 85kd regulatory subunit,
which allows it to bind to activated tyrosine protein kinases. PI3 kinase 
P85 alpha subunits contain an N-terminal SH3 domain, and two SH2 domains in
the C-terminal half of the sequence. 
 
PI3KINASEP85 is a 10-element fingerprint that provides a signature for
PI3 kinase P85-alpha subunits. The fingerprint was derived from an initial
alignment of 8 sequences: the motifs were drawn from conserved regions
spanning the C-terminal half of the alignment - motifs 1 and 2 lie in the
first SH2 domain; and motifs 8-10 span the second SH2 domain. Two
iterations on OWL 29.1 were required to reach convergence, at which point
a true set comprising 13 sequences was identified.     
 
An update on SPTR37_9f identified a true set of 13 sequences, and 2
partial matches.
Summary Information
  13 codes involving 10 elements
0 codes involving 9 elements
1 codes involving 8 elements
0 codes involving 7 elements
0 codes involving 6 elements
0 codes involving 5 elements
1 codes involving 4 elements
0 codes involving 3 elements
0 codes involving 2 elements
Composite Feature Index
1013131313131313131313
90000000000
81111100111
70000000000
60000000000
50000000000
41100000101
30000000000
20000000000
12345678910
True Positives
O46404        P70304        P85A_BOVIN    P85A_HUMAN    
P85A_MOUSE P85A_RAT P85B_BOVIN P85B_HUMAN
P85B_MOUSE P85B_RAT Q63789 Q64143
Q92569
True Positive Partials
Codes involving 8 elements
O60482
Codes involving 4 elements
O18683
Sequence Titles
O46404      PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY GAMMA SUBUNIT (PI3-KINASE P55-GAMMA SUBUNIT) (P55PIK) (P55-GAMMA) - BOS TAURUS (BOVINE). 
P70304 PHOSPHATIDYLINOSITOL 3-KINASE, REGULATORY SUBUNIT, POLYPEPTIDE 1 (P85 ALPHA) (PHOSPHOINOSITIDE 3-KINASE P85ALPHA) - MUS MUSCULUS (MOUSE).
P85A_BOVIN PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT (PI3-KINASE P85-ALPHA SUBUNIT) (PTDINS-3-KINASE P85-ALPHA) (PI3K) - BOS TAURUS (BOVINE).
P85A_HUMAN PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT (PI3-KINASE P85-ALPHA SUBUNIT) (PTDINS-3-KINASE P85-ALPHA) (PI3K) - HOMO SAPIENS (HUMAN).
P85A_MOUSE PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT (PI3-KINASE P85-ALPHA SUBUNIT) (PTDINS-3-KINASE P85-ALPHA) (PI3K) - MUS MUSCULUS (MOUSE).
P85A_RAT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT (PI3-KINASE P85-ALPHA SUBUNIT) (PTDINS-3-KINASE P85-ALPHA) (PI3K) - RATTUS NORVEGICUS (RAT).
P85B_BOVIN PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY BETA SUBUNIT (PI3-KINASE P85-BETA SUBUNIT) (PTDINS-3-KINASE P85-BETA) - BOS TAURUS (BOVINE).
P85B_HUMAN PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY BETA SUBUNIT (PI3-KINASE P85-BETA SUBUNIT) (PTDINS-3-KINASE P85-BETA) - HOMO SAPIENS (HUMAN).
P85B_MOUSE PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY BETA SUBUNIT (PI3-KINASE P85-BETA SUBUNIT) (PTDINS-3-KINASE P85-BETA) - MUS MUSCULUS (MOUSE).
P85B_RAT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY BETA SUBUNIT (PI3-KINASE P85-BETA SUBUNIT) (PTDINS-3-KINASE P85-BETA) - RATTUS NORVEGICUS (RAT).
Q63789 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY GAMMA SUBUNIT (PI3-KINASE P55-GAMMA SUBUNIT) (P55PIK) (P55-GAMMA) - RATTUS NORVEGICUS (RAT).
Q64143 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY GAMMA SUBUNIT (PI3-KINASE P55-GAMMA SUBUNIT) (P55PIK) (P55-GAMMA) - MUS MUSCULUS (MOUSE).
Q92569 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY GAMMA SUBUNIT (PI3-KINASE P55-GAMMA SUBUNIT) (P55PIK) (P55-GAMMA) - HOMO SAPIENS (HUMAN).

O60482 PHOSPHATIDYLINOSITOL 3-KINASE P55 GAMMA REGULATORY SUBUNIT - HOMO SAPIENS (HUMAN).

O18683 P60 - DROSOPHILA MELANOGASTER (FRUIT FLY).
Scan History
OWL29_1    2  50   NSINGLE    
SPTR37_9f 2 74 NSINGLE
Initial Motifs
Motif 1  width=19
Element Seqn Id St Int Rpt
SLQDAEWYWGDISREEVNE P85B_BOVIN 320 320 -
SLQNAEWYWGDISREEVNE P85A_HUMAN 327 327 -
SLQDAEWYWGDISREEVNE P85A_MOUSE 327 327 -
SLQDAEWYWGDISREEVNE P85A_BOVIN 327 327 -
SLQDAEWYWGDISREEVNE RATP3KA 327 327 -
SLQDAEWYWGDISREEVNE RATP3KB 318 318 -
SLQDAEWYWGDISREEVNE A38747 327 327 -
SLQDAEWYWGDISREEVNE RATP3KD 57 57 -

Motif 2 width=15
Element Seqn Id St Int Rpt
FHRDGHYGFSEPLTF P85B_BOVIN 377 38 -
FHRDGKYGFSDPLTF P85A_HUMAN 384 38 -
FHRDGKYGFSDPLTF P85A_MOUSE 384 38 -
FHRDGKYGFSDPLTF P85A_BOVIN 384 38 -
FHRDGKYGFSDPLTF A38747 384 38 -
FHRDGKYGFSDPLTF RATP3KA 384 38 -
FHRDGHYGFSEPLTF RATP3KB 375 38 -
FHRDGKYGFSDPLTF RATP3KD 114 38 -

Motif 3 width=24
Element Seqn Id St Int Rpt
RLLYPVSKYQQDQVVKEDSVEAVG RATP3KB 414 24 -
KLLYPVSKYQQDQVVKEDNIEAVG A38747 423 24 -
KLLYPVSKYQQDQVVKEDNIEAVG RATP3KA 423 24 -
KLLYPVSKYQQDQVVKEDNIEAVG RATP3KD 153 24 -
KLLYPVSKYQQDQVVKEDNIEAVG P85A_BOVIN 423 24 -
KLLYPVSKYQQDQVVKEDNIEAVG P85A_MOUSE 423 24 -
KLLYPVSKYQQDQVVKEDNIEAVG P85A_HUMAN 423 24 -
RLLYPVSKYQQDQIVKEDSVEAVG P85B_BOVIN 416 24 -

Motif 4 width=19
Element Seqn Id St Int Rpt
AFNETIKIFEEQGQTQEKC P85B_BOVIN 479 39 -
AFNETIKIFEEQCQTQERY P85A_HUMAN 486 39 -
AFNETIKIFEEQCQTQERY P85A_MOUSE 486 39 -
AFNETIKIFEEQCQTQERY P85A_BOVIN 486 39 -
AFNDTIKIFEEQCHPQERY RATP3KD 216 39 -
AFNETILIFEEQGQTQEKC RATP3KB 477 39 -
AFNDTIKIFEEQCHPQERY RATP3KA 486 39 -
AFNETIKIFEEQCQTQERY A38747 486 39 -

Motif 5 width=23
Element Seqn Id St Int Rpt
SKDYIEKFKREGNEKEIQRIMHN RATP3KD 235 0 -
SKEYLERFRREGNEKEMQRILLN RATP3KB 496 0 -
SKDYIEKFKREGNEKEIQRIMHN RATP3KA 505 0 -
SKEYIGKFKREGNEKEIQRIMHN A38747 505 0 -
SKEYLERFRREGNEKEMQRILLN P85B_BOVIN 498 0 -
SKEYIEKFKREGNEKEIQRIMHN P85A_HUMAN 505 0 -
SKEYIGKFKREGNEKEIQRIMHN P85A_MOUSE 505 0 -
SKEYIEKFKREGNETEIQRIMHN P85A_BOVIN 505 0 -

Motif 6 width=20
Element Seqn Id St Int Rpt
REIDKRMNSIKPDLIQLRKT A38747 557 29 -
REIDKRMNSIKPDLIQLRKT P85A_HUMAN 557 29 -
REIDKRMNSIKPDLIQLRKT P85A_MOUSE 557 29 -
REIDKRMNSIKPDLIQLRKT P85A_BOVIN 557 29 -
REIDKRMNSIKPDLIQLRKT RATP3KD 287 29 -
REIDKRMNSLKPDLMQLRKI RATP3KB 548 29 -
REIDKRMNSIKPDLIQLRKT RATP3KA 557 29 -
REIDKRMNSLKPDLMQLRKI P85B_BOVIN 550 29 -

Motif 7 width=26
Element Seqn Id St Int Rpt
RDQYLMWLTQKGVRQKKLNEWLGNEN P85A_MOUSE 577 0 -
RDQYLMWLTQKGVRQKKLNEWLGNEN RATP3KA 577 0 -
RDQYLVWLTQKGARQRKINEWLGIKN RATP3KB 568 0 -
RDQYLMWLTQKGVRQKKLNEWLGNEN RATP3KD 307 0 -
RDQYLMWLTQKGVRQKKLNEWLGNEN P85A_BOVIN 577 0 -
RDQYLMWLTQKGVRQKKLNEWLGNEN A38747 577 0 -
RDQYLMWLTQKGVRQKKLNEWLGNEN P85A_HUMAN 577 0 -
RDQYLVWLTQKGARQKKINEWLGIKN P85B_BOVIN 570 0 -

Motif 8 width=23
Element Seqn Id St Int Rpt
NRTQAEEMLSGKRDGTFLIRESS P85B_BOVIN 624 28 -
NRNKAENLLRGKRDGTFLVRESS RATP3KD 360 27 -
NRTQAEEMLSAKRDGTFLIRESS RATP3KB 622 28 -
NRNKAENLLRGKRDGTFLVRESS RATP3KA 630 27 -
NRNKAENLLRGKRDGTFLVRESS A38747 630 27 -
NRNKAENLLRGKRDGTFLVRESS P85A_BOVIN 630 27 -
NRNKAENLLRGKRDGTFLVRESS P85A_MOUSE 630 27 -
NRNKAENLLRGKRDGTFLVRESS P85A_HUMAN 630 27 -

Motif 9 width=18
Element Seqn Id St Int Rpt
GCYACSVVVDGEVKHCVI P85A_BOVIN 655 2 -
GCYACSVVVDGEVKHCVI P85A_MOUSE 655 2 -
GCYACSVVVDGEVKHCVI P85A_HUMAN 655 2 -
GCYACSVVVDGDTKHCVI P85B_BOVIN 649 2 -
GCYACSVVVDGEVKHCVI RATP3KD 385 2 -
GCYACSVVVDGDTKHCVI RATP3KB 647 2 -
GCYACSVVVDGEVKHCVI RATP3KA 655 2 -
GCYACSVVVDGEVKHCVI A38747 655 2 -

Motif 10 width=26
Element Seqn Id St Int Rpt
TATGYGFAEPYNLYSSLKELVLHYQH P85A_BOVIN 675 2 -
TATGFGFAEPYNLYGSLKELVLHYQH RATP3KB 667 2 -
TATGYGFAEPYNLYSSLKELVLHYQH RATP3KA 675 2 -
TATGYGFAEPYNLYSSLKELVIHYQH A38747 675 2 -
TATGFGFAEPYNLYGSLKELVLHYQH P85B_BOVIN 669 2 -
TATGYGFAEPYNLYSSLKELVLHYQH P85A_HUMAN 675 2 -
TATGYGFAEPYNLYSSLKELVLHYQH P85A_MOUSE 675 2 -
TATGYGFAEPYNLYSSLKELVLHYQH RATP3KD 405 2 -
Final Motifs
Motif 1  width=19
Element Seqn Id St Int Rpt
SLQDAEWYWGDISREEVNE P70304 327 327 -
SLQDAEWYWGDISREEVNE P85A_BOVIN 327 327 -
SLQDAEWYWGDISREEVNE P85A_MOUSE 327 327 -
SLQNAEWYWGDISREEVNE P85A_HUMAN 327 327 -
SLQDAEWYWGDISREEVNE P85A_RAT 327 327 -
SLQDAEWYWGDISREEVNE P85B_MOUSE 318 318 -
SLQDAEWYWGDISREEVNE P85B_BOVIN 320 320 -
SLQDAEWYWGDISREEVNE P85B_HUMAN 324 324 -
SLQDAEWYWGDISREEVND Q92569 59 59 -
SLQDAEWYWGDISREEVNE P85B_RAT 318 318 -
SLQDAEWYWGDISREEVND O46404 59 59 -
SLQDAEWYWGDISREEVND Q64143 59 59 -
SLQDAEWYWGDISREEVND Q63789 59 59 -

Motif 2 width=15
Element Seqn Id St Int Rpt
FHRDGKYGFSDPLTF P70304 384 38 -
FHRDGKYGFSDPLTF P85A_BOVIN 384 38 -
FHRDGKYGFSDPLTF P85A_MOUSE 384 38 -
FHRDGKYGFSDPLTF P85A_HUMAN 384 38 -
FHRDGKYGFSDPLTF P85A_RAT 384 38 -
FHRDGHYGFSEPLTF P85B_MOUSE 375 38 -
FHRDGHYGFSEPLTF P85B_BOVIN 377 38 -
FHRDGHYGFSEPLTF P85B_HUMAN 381 38 -
YHRDGKYGFSDPLTF Q92569 116 38 -
FHRDGHYGFSEPLTF P85B_RAT 375 38 -
YHRDGKYGFSDPLTF O46404 116 38 -
YHRDGKYGFSEPLTF Q64143 116 38 -
YHRDGNYGFSEPLTF Q63789 116 38 -

Motif 3 width=24
Element Seqn Id St Int Rpt
KLLYPVSKYQQDQVVKEDNIEAVG P70304 423 24 -
KLLYPVSKYQQDQVVKEDNIEAVG P85A_BOVIN 423 24 -
KLLYPVSKYQQDQVVKEDNIEAVG P85A_MOUSE 423 24 -
KLLYPVSKYQQDQVVKEDNIEAVG P85A_HUMAN 423 24 -
KLLYPVSKYQQDQVVKEDNIEAVG P85A_RAT 423 24 -
RLLYPVSKYQQDQVVKEDSVEAVG P85B_MOUSE 414 24 -
RLLYPVSKYQQDQIVKEDSVEAVG P85B_BOVIN 416 24 -
RLLYPVSKYQQDQIVKEDSVEAVG P85B_HUMAN 420 24 -
KLMYPVSRYQQDQLVKEDNIDAVG Q92569 155 24 -
RLLYPVSKYQQDQVVKEDSVEAVG P85B_RAT 414 24 -
KLMYPVSRYQQDQLVKEDNIDAVG O46404 155 24 -
KLTYPVSRFQQDQLVKEDNIDAVG Q64143 155 24 -
KLMYPVSRYQQDQLVKEDNIDAVG Q63789 155 24 -

Motif 4 width=19
Element Seqn Id St Int Rpt
AFNETIKIFEEQCQTQERY P70304 486 39 -
AFNETIKIFEEQCQTQERY P85A_BOVIN 486 39 -
AFNETIKIFEEQCQTQERY P85A_MOUSE 486 39 -
AFNETIKIFEEQCQTQERY P85A_HUMAN 486 39 -
AFNDTIKIFEEQCHPQERY P85A_RAT 486 39 -
AFNETIKIFEEQGQTQEKC P85B_MOUSE 477 39 -
AFNETIKIFEEQGQTQEKC P85B_BOVIN 479 39 -
AFNETIKIFEEQGQTQEKC P85B_HUMAN 483 39 -
AFNETIKIFEEQCHTQEQH Q92569 218 39 -
AFNETILIFEEQGQTQEKC P85B_RAT 477 39 -
AFNETIKIFEEQCHTQEQH O46404 218 39 -
AFNETIKIFEEQCHTQEQH Q64143 218 39 -
AFNETIKIFEEQCHTQEQH Q63789 218 39 -

Motif 5 width=23
Element Seqn Id St Int Rpt
SKEYIEKFKREGNEKEIQRIMHN P70304 505 0 -
SKEYIEKFKREGNETEIQRIMHN P85A_BOVIN 505 0 -
SKEYIGKFKREGNEKEIQRIMHN P85A_MOUSE 505 0 -
SKEYIEKFKREGNEKEIQRIMHN P85A_HUMAN 505 0 -
SKDYIEKFKREGNEKEIQRIMHN P85A_RAT 505 0 -
SKEYLERFRREGNEKEMQRILLN P85B_MOUSE 496 0 -
SKEYLERFRREGNEKEMQRILLN P85B_BOVIN 498 0 -
SKEYLERFRREGNEKEMQRILLN P85B_HUMAN 502 0 -
SKEYIERFRREGNEKEIERIMMN Q92569 237 0 -
SKEYLERFRREGNEKEMQRILLN P85B_RAT 496 0 -
SKEYIERFRKEGNEKEIERIMMN O46404 237 0 -
SKDYIERFRREGNEKEIERIMMN Q64143 237 0 -
SKDYIERFRREGNEKEIERIMMN Q63789 237 0 -

Motif 6 width=20
Element Seqn Id St Int Rpt
REIDKRMNSIKPDLIQLRKT P70304 557 29 -
REIDKRMNSIKPDLIQLRKT P85A_BOVIN 557 29 -
REIDKRMNSIKPDLIQLRKT P85A_MOUSE 557 29 -
REIDKRMNSIKPDLIQLRKT P85A_HUMAN 557 29 -
REIDKRMNSIKPDLIQLRKT P85A_RAT 557 29 -
REIDKRMNSLKPDLMQLRKI P85B_MOUSE 548 29 -
REIDKRMNSLKPDLMQLRKI P85B_BOVIN 550 29 -
REIDKRMNSLKPDLMQLRKI P85B_HUMAN 554 29 -
REIDKKMNSIKPDLIQLRKI Q92569 289 29 -
REIDKRMNSLKPDLMQLRKI P85B_RAT 548 29 -
REIDKKMNSIKPDLIRLRKI O46404 289 29 -
REIDKKMNSIKPDLIQLRKI Q64143 289 29 -
REIDKKMNSIKPDLIQLRKI Q63789 289 29 -

Motif 7 width=26
Element Seqn Id St Int Rpt
RDQYLMWLTQKGVRQKKLNEWLGNEN P70304 577 0 -
RDQYLMWLTQKGVRQKKLNEWLGNEN P85A_BOVIN 577 0 -
RDQYLMWLTQKGVRQKKLNEWLGNEN P85A_MOUSE 577 0 -
RDQYLMWLTQKGVRQKKLNEWLGNEN P85A_HUMAN 577 0 -
RDQYLMWLTQKGVRQKKLNEWLGNEN P85A_RAT 577 0 -
RDQYLVWLTQKGARQRKINEWLGIKN P85B_MOUSE 568 0 -
RDQYLVWLTQKGARQKKINEWLGIKN P85B_BOVIN 570 0 -
RDQYLVWLTQKGARQKKINEWLGIKN P85B_HUMAN 574 0 -
RDQHLVWLNHKGVRQKRLNVWLGIKN Q92569 309 0 -
RDQYLVWLTQKGARQRKINEWLGIKN P85B_RAT 568 0 -
RDQHLVWLNHKGVRQKRLNAWLGIKN O46404 309 0 -
RDQHLVWLNHRGVRQRRLNAWLGIKN Q64143 309 0 -
RDQHLVWLNHRGVRQRRLNAWLGIKS Q63789 309 0 -

Motif 8 width=23
Element Seqn Id St Int Rpt
NRNKAENLLRGKRDGTFLVRESS P70304 630 27 -
NRNKAENLLRGKRDGTFLVRESS P85A_BOVIN 630 27 -
NRNKAENLLRGKRDGTFLVRESS P85A_MOUSE 630 27 -
NRNKAENLLRGKRDGTFLVRESS P85A_HUMAN 630 27 -
NRNKAENLLRGKRDGTFLVRESS P85A_RAT 630 27 -
NRTQAEEMLSGKRDGTFLIRESS P85B_MOUSE 622 28 -
NRTQAEEMLSGKRDGTFLIRESS P85B_BOVIN 624 28 -
NRTQAEEMLSGKRDGTFLIRESS P85B_HUMAN 628 28 -
NRVQAEDLLYGKPDGAFLIRESS Q92569 364 29 -
NRTQAEEMLSAKRDGTFLIRESS P85B_RAT 622 28 -
NRVQAEDLLYGKPDGAFLIRESS O46404 364 29 -
NRVQAEDLLYGKPDGAFLIRESS Q64143 364 29 -
NRVQAEDLLYGKPDGAFLIRESS Q63789 364 29 -

Motif 9 width=18
Element Seqn Id St Int Rpt
GCYACSVVVDGEVKHCVI P70304 655 2 -
GCYACSVVVDGEVKHCVI P85A_BOVIN 655 2 -
GCYACSVVVDGEVKHCVI P85A_MOUSE 655 2 -
GCYACSVVVDGEVKHCVI P85A_HUMAN 655 2 -
GCYACSVVVDGEVKHCVI P85A_RAT 655 2 -
GCYACSVVVDGDTKHCVI P85B_MOUSE 647 2 -
GCYACSVVVDGDTKHCVI P85B_BOVIN 649 2 -
GCYACSVVVDGDTKHCVI P85B_HUMAN 653 2 -
GCYACSVVADGEVKHCVI Q92569 389 2 -
GCYACSVVVDGDTKHCVI P85B_RAT 647 2 -
GCYACSVVADGEVKHCVI O46404 389 2 -
GCYACSVVADGEVKHCVI Q64143 389 2 -
GCYACSVVADGEVKPCVI Q63789 389 2 -

Motif 10 width=26
Element Seqn Id St Int Rpt
TATGYGFAEPYNLYSSLKELVLHYQH P70304 675 2 -
TATGYGFAEPYNLYSSLKELVLHYQH P85A_BOVIN 675 2 -
TATGYGFAEPYNLYSSLKELVLHYQH P85A_MOUSE 675 2 -
TATGYGFAEPYNLYSSLKELVLHYQH P85A_HUMAN 675 2 -
TATGYGFAEPYNLYSSLKELVLHYQH P85A_RAT 675 2 -
TATGFGFAEPYNLYGSLKELVLHYQH P85B_MOUSE 667 2 -
TATGFGFAEPYNLYGSLKELVLHYQH P85B_BOVIN 669 2 -
TATGFGFAEPYNLYGSLKELVLHYQH P85B_HUMAN 673 2 -
TARGYGFAEPYNLYSSLKELVLHYQQ Q92569 409 2 -
TATGFGFAEPYNLYGSLKELVLHYQH P85B_RAT 667 2 -
TARGYGFAEPYNLYGSLKELVLHYQR O46404 409 2 -
TARGYGFAEPYNLYSSLKELVLHYQQ Q64143 409 2 -
PARGYGFAEPYNLYGSLKELVLHYQQ Q63789 409 2 -