| Identifier | D12N6MTFRASE [View Relations] [View Alignment]
|
| Accession | PR00505 |
| No. of Motifs | 4 |
| Creation Date | 21-MAY-1996 (UPDATE 27-JUN-1999) |
| Title | D12 class N6 adenine-specific DNA methyltransferase signature |
| Database References |
PROSITE; PS00092 N6_MTASE
BLOCKS; BL00092
INTERPRO; IPR002294
PDB; 1ADM
SCOP; 1ADM
|
| Literature References | 1. CHENG, X.
Structure and function of DNA methyltransferases.
ANNU.REV.BIOPHYS.BIOMOL.STRUCT. 24 293-318 (1995).
2. LABAHN, J., GRANZIN, J., SCHLUCKEBIER, G., ROBINSON, D.P., JACK, W.E.,
SCHILDKRAUT, I. AND SAENGER, W.
Three-dimensional structure of the adenine-specific DNA methyltransferase
M.TaqI in complex with the cofactor S-adenosylmethionine.
PROC.NATL.ACAD.SCI.U.S.A. 91 10957-10961 (1994).
3. TIMINSKAS, A., BUTKUS, V. AND JANULAITIS, A.
Sequence motifs characteristic for DNA [cytosine-N4] and DNA [adenine-N6]
methyltransferases. Classification of all DNA methyltransferases.
GENE 157 3-11 (1995).
4. WILLCOCK, D.F., DRYDEN, D.T. AND MURRAY, N.E.
A mutational analysis of the two motifs common to adenine
methyltransferases.
EMBO J. 13 3902-3908 (1994).
|
| Documentation | In prokaryotes, the major role of DNA methylation is to protect host
DNA against degradation by restriction enzymes. There are 2 major classes
of DNA methyltransferase that differ in the nature of the modifications
they effect [1]. The members of one class (C-MTases) methylate a ring
carbon and form C5-methylcytosine (see PRINTS signature C5METTRFRASE).
Members of the second class (N-MTases) methylate exocyclic nitrogens and
form either N4-methylcytosine (N4-MTases) or N6-methyladenine (N6-MTases).
Both classes of MTase utilise the cofactor S-adenosyl-L-methionine (SAM)
as the methyl donor and are active as monomeric enzymes [1].
The structure of N6-MTase TaqI (M.TaqI) has been resolved to 2.4A [2].
The molecule folds into 2 domains: an N-terminal catalytic domain, which
contains the catalytic and cofactor binding sites, and comprises a central
9-stranded beta-sheet, surrounded by 5 helices; and a C-terminal DNA
recognition domain, which is formed by 4 small beta-sheets and 8 alpha-
helices. The N- and C-terminal domains form a cleft that accommodates the
DNA substrate.
A classification of N-MTases has been proposed, based on conserved motif
(CM) arrangements [3]. According to this classification, N6-MTases that
have a DPPY motif (CM II) occuring after the FxGxG motif (CM I) are
designated D12 class N6-adenine MTases.
D12N6MTFRASE is a 4-element fingerprint that provides a signature for the
D12 class N6-adenine MTases. The fingerprint was derived from an initial
alignment of 14 sequences (note that sequences MTF1_FLAOK, MTL1_LACLA and
MTS1_STRSA contain internal duplications and both sets of motifs were used).
The motifs were drawn from some of the conserved regions used by Timinskas
et al. [3] in their DNA MTase classification: motifs 1, 2 and 4 correspond
to CM Is, I and II, respectively - motif 2, which contains the FxGxG
pattern, forms part of the cofactor (SAM) binding site; and motif 4, which
contains the N-MTase-specific tetrapeptide DPPY (cf. PROSITE pattern
N6_MTASE), is important for methylation [4]. Two iterations on OWL27.1 were
required to reach convergence, at which point a true set comprising 20
sequences was identified. A few partial matches were also found: NGOCPSPS2
is a hypothetical protein in Neisseria meningitidis capsule gene complex
(cps), which fails to match motif 4; MTEC_ENTCL (M.EcaI), which matches
motifs 2 and 3, is a D21 class N6-adenine MTase, with CM II occuring before
CM I; and YHHF_HAEIN, YF23_HAEIN and MTU000243 are hypothetical proteins
matching motifs 2 and 4, which may be regarded as potential D12 class
N6-adenine MTases.
An update on SPTR37_9f identified a true set of 35 sequences, and 6
partial matches.
|
| Summary Information | 35 codes involving 4 elements
3 codes involving 3 elements
3 codes involving 2 elements
|
| Composite Feature Index | |
| True Positives | DMA7_ECOLI DMA_BPT2 DMA_BPT4 DMA_ECOLI
DMA_HAEIN DMA_SALTY DMA_SERMA ML21_LACLC
MT1A_MORBO MT21_STRPN MT61_METJA MTC1_CHVN1
MTC2_CHVP1 MTE5_ECOLI MTF1_FLAOK MTHA_HAEPH
MTL1_LACLA MTN3_NEILA MTS1_STRSA O25809
O30358 O30889 O30892 O30893
O37398 O37399 O41063 O58765
P71101 P74637 P95820 Q47911
Q51829 Q56004 Q96718 |
| True Positive Partials | |
| Sequence Titles | DMA7_ECOLI RETRON EC67 DNA ADENINE METHYLASE (EC 2.1.1.72) (ORF1-EC67 DAM) - ESCHERICHIA COLI.
DMA_BPT2 DNA ADENINE METHYLASE (EC 2.1.1.72) (DEOXYADENOSYL-METHYLTRANSFERASE) - BACTERIOPHAGE T2.
DMA_BPT4 DNA ADENINE METHYLASE (EC 2.1.1.72) (DEOXYADENOSYL-METHYLTRANSFERASE) - BACTERIOPHAGE T4.
DMA_ECOLI DNA ADENINE METHYLASE (EC 2.1.1.72) (DEOXYADENOSYL-METHYLTRANSFERASE) - ESCHERICHIA COLI.
DMA_HAEIN DNA ADENINE METHYLASE (EC 2.1.1.72) (DEOXYADENOSYL-METHYLTRANSFERASE) - HAEMOPHILUS INFLUENZAE.
DMA_SALTY DNA ADENINE METHYLASE (EC 2.1.1.72) (DEOXYADENOSYL-METHYLTRANSFERASE) - SALMONELLA TYPHIMURIUM.
DMA_SERMA DNA ADENINE METHYLASE (EC 2.1.1.72) (DEOXYADENOSYL-METHYLTRANSFERASE) - SERRATIA MARCESCENS.
ML21_LACLC MODIFICATION METHYLASE LLADCHI A (EC 2.1.1.72) (ADENINE-SPECIFIC METHYLTRANSFERASE LLADCHI A) (M.LLADCHI A) (LLAII) - LACTOCOCCUS LACTIS (SUBSP. CREMORIS) (STREPTOCOCCUS CREMORIS).
MT1A_MORBO MODIFICATION METHYLASE MBOI A (EC 2.1.1.72) (ADENINE-SPECIFIC METHYLTRANSFERASE MBOI A) (M.MBOI A) - MORAXELLA BOVIS.
MT21_STRPN MODIFICATION METHYLASE DPNII 1 (EC 2.1.1.72) (ADENINE-SPECIFIC METHYLTRANSFERASE DPNII 1) (M.DPNII 1) - STREPTOCOCCUS PNEUMONIAE.
MT61_METJA PROBABLE MODIFICATION METHYLASE MJ0598 (EC 2.1.1.72) (ADENINE-SPECIFIC METHYLTRANSFERASE MJ0598) - METHANOCOCCUS JANNASCHII.
MTC1_CHVN1 MODIFICATION METHYLASE CVIBI (EC 2.1.1.72) (ADENINE-SPECIFIC METHYLTRANSFERASE CVIBI) (M.CVIBI) - CHLORELLA VIRUS NC-1A (CV-NC1A).
MTC2_CHVP1 MODIFICATION METHYLASE CVIAII (EC 2.1.1.72) (ADENINE-SPECIFIC METHYLTRANSFERASE CVIAII) (M.CVIAII) - PARAMECIUM BURSARIA CHLORELLA VIRUS 1 (PBCV-1).
MTE5_ECOLI MODIFICATION METHYLASE ECORV (EC 2.1.1.72) (ADENINE-SPECIFIC METHYLTRANSFERASE ECORV) (M.ECORV) - ESCHERICHIA COLI.
MTF1_FLAOK MODIFICATION METHYLASE FOKI (EC 2.1.1.72) (ADENINE-SPECIFIC METHYLTRANSFERASE FOKI) (M.FOKI) - FLAVOBACTERIUM OKEANOKOITES.
MTHA_HAEPH MODIFICATION METHYLASE HPHI(A) (EC 2.1.1.72) (ADENINE-SPECIFIC METHYLTRANSFERASE HPHI(A)) (M.HPHI(A)) - HAEMOPHILUS PARAHAEMOLYTICUS.
MTL1_LACLA MODIFICATION METHYLASE LLAI (EC 2.1.1.72) (ADENINE-SPECIFIC METHYLTRANSFERASE LLAI) (M.LLAI) - LACTOCOCCUS LACTIS (SUBSP. LACTIS) (STREPTOCOCCUS LACTIS).
MTN3_NEILA MODIFICATION METHYLASE NLAIII (EC 2.1.1.72) (ADENINE-SPECIFIC METHYLTRANSFERASE NLAIII) (M.NLAIII) - NEISSERIA LACTAMICA.
MTS1_STRSA MODIFICATION METHYLASE STSI (EC 2.1.1.72) (ADENINE-SPECIFIC METHYLTRANSFERASE STSI) (M.STSI) - STREPTOCOCCUS SANGUIS.
O25809 ULCER ASSOCIATED ADENINE SPECIFIC DNA METHYLTRANSFERASE - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).
O30358 N6-METHYLADENINE METHYLTRANSFERASE - NEISSERIA GONORRHOEAE.
O30889 METHYLASE HPYI - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).
O30892 METHYLASE HPYI - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).
O30893 METHYLASE HPYI - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).
O37398 DNA ADENINE METHYLTRANSFERASE - CHLORELLA VIRUS NY-2A (CV-NY2A).
O37399 DNA ADENINE METHYLTRANSFERASE - CHLORELLA VIRUS NY-2A (CV-NY2A).
O41063 PBCV-1 M.CVIAI METHYLASE - PARAMECIUM BURSARIA CHLORELLA VIRUS 1 (PBCV-1).
O58765 330AA LONG HYPOTHETICAL MODIFICATION METHYLASE (ADENINE-SPECIFIC) - PYROCOCCUS HORIKOSHII.
P71101 METHYLTRANSFERASE - CURTOBACTERIUM ALBIDUM.
P74637 HYPOTHETICAL 32.9 KD PROTEIN - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
P95820 SPHI METHYLTRANSFERASE - STREPTOMYCES PHAEOCHROMOGENES.
Q47911 FOKIR AND FOKIM GENES ENCODING ENODONUCLEASE AND METHYLTRANSFERASE, COMPLETE CDS - FLAVOBACTERIUM OKEANOKOITES.
Q51829 PGI METHYLASE - PORPHYROMONAS GINGIVALIS (BACTEROIDES GINGIVALIS).
Q56004 DNA-METHYLTRANSFERASE - SPOROSARCINA SP.
Q96718 DNA ADENINE METHYLTRANSFERASE - CHLORELLA VIRUS SC-1A.
DMA_TREPA DNA ADENINE METHYLASE (EC 2.1.1.72) (DEOXYADENOSYL-METHYLTRANSFERASE) - TREPONEMA PALLIDUM.
P73682 ADENINE-SPECIFIC DNA METYLASE - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
Q51153 DTDP-D-GLUCOSE 4,6-DEHYDRATASE (RFBB), GLUCOSE-1-PHOSPHATE THYMIDYL TRANSFERASE (RFBA) AND RFBC GENES, COMPLETE CDS AND UPD-GLUCOSE-4-EPIMERASE (GALE) PSEUDOGENE (RFBA) (GALE) - NEISSERIA MENINGITIDIS.
O51224 CONSERVED HYPOTHETICAL PROTEIN - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
O84494 METHYLASE - CHLAMYDIA TRACHOMATIS.
Y710_METJA HYPOTHETICAL PROTEIN MJ0710 - METHANOCOCCUS JANNASCHII.
|
| Scan History | OWL27_1 2 300 NSINGLE
SPTR37_9f 2 110 NSINGLE
|
| Initial Motifs | Motif 1 width=17
Element Seqn Id St Int Rpt
WAGGKYPLVDEIRRHLP DMA_SERMA 10 10 -
WTGGKRQLLPVIRELIP MT21_STRPN 17 17 -
FIGSKVNLLDNIQEVIE MTF1_FLAOK 3 3 -
YVGGKHKLLNQIVPLFP MTF1_FLAOK 371 371 -
YTGNKQSLLPELKPHFP DMA_BPT2 7 7 -
YTGNKQSLLPELKSHFP DMA_BPT4 7 7 -
YIGSKLKLSNWLETEIS MTN3_NEILA 3 3 -
YIGSKKLLLPEIKKMVD MTS1_STRSA 3 3 -
YIGGKYKLLNQILPLFP MTS1_STRSA 369 369 -
WAGGKNSLLDEIQKRLP MT1A_MORBO 7 7 -
WAGGKFRLTDEINKAFP DMA_HAEIN 21 21 -
WAGNKTAIMSELKKHLP DMA7_ECOLI 7 7 -
YIGSKLKLKDWIFEEIS MTC2_CHVP1 6 6 -
SQGIKTKLVPCIKRIVP MTE5_ECOLI 12 12 -
YLGNKTNLLNFIQQVIK MTL1_LACLA 3 3 -
YAGSKDDVIPRIFKLLP MTL1_LACLA 353 353 -
WSGGKTDELKRFEDYIP MTC1_CHVN1 7 7 -
Motif 2 width=15
Element Seqn Id St Int Rpt
LIEPFVGAGSVFLNT DMA_SERMA 31 4 -
YFEPFVGGGALFFDL MT21_STRPN 39 5 -
FMDLFSGTGIVGENF MTF1_FLAOK 29 9 -
FVDLFSGGFNVGINV MTF1_FLAOK 393 5 -
FVDLFCGGLSVSLNV DMA_BPT2 28 4 -
FVDLFCGGLSVSLNV DMA_BPT4 28 4 -
FCDLFAGTGIVGRKF MTN3_NEILA 31 11 -
FLDLFAGTNVVANYF MTS1_STRSA 29 9 -
FVDIFSGGANVGINV MTS1_STRSA 391 5 -
LVEPFVGGGAVSLWA MT1A_MORBO 33 9 -
LIEPFVGAGAVFLNS DMA_HAEIN 43 5 -
LVEPFAGSCAVMMAT DMA7_ECOLI 28 4 -
FADLFAGSCIMTHEA MTC2_CHVP1 32 9 -
WVEPFMGTGVVAFNV MTE5_ECOLI 35 6 -
FADLFAGTGSVGDYF MTL1_LACLA 28 8 -
FVDAMGGAFNVGANR MTL1_LACLA 375 5 -
FIEPFAGGAATFFHV MTC1_CHVN1 29 5 -
Motif 3 width=14
Element Seqn Id St Int Rpt
YILADINSDLINLY DMA_SERMA 50 4 -
AVINDFNAELINCY MT21_STRPN 58 4 -
VLSNDSLYFSYILL MTF1_FLAOK 49 5 -
IIATDINTYVVEVL MTF1_FLAOK 412 4 -
VLANDIQEPIIEMY DMA_BPT2 46 3 -
VLANDIQEPIIEMY DMA_BPT4 46 3 -
VIANDMEYYSYVLN MTN3_NEILA 52 6 -
VYSNDMLFFSYVNA MTS1_STRSA 49 5 -
YIFNDMNTRINEMF MTS1_STRSA 410 4 -
LVINDCNADLINVY MT1A_MORBO 57 9 -
YILADINPDLINLF DMA_HAEIN 62 4 -
YLVADINPDLINLY DMA7_ECOLI 47 4 -
CISNDLETYPYVIM MTC2_CHVP1 53 6 -
ALLCDTNPHLISFY MTE5_ECOLI 54 4 -
VLSNDYMYFSKVIS MTL1_LACLA 48 5 -
VVYNEYHPFVFEMM MTL1_LACLA 395 5 -
KVLSDVHVELVALY MTC1_CHVN1 50 6 -
Motif 4 width=13
Element Seqn Id St Int Rpt
GAVVYCDPPYAPL DMA_SERMA 175 111 -
GDFVYFDPPYIPL MT21_STRPN 188 116 -
GDILYIDPPYNGR MTF1_FLAOK 212 149 -
NDLVYCDPPYLIT MTF1_FLAOK 542 116 -
GDFVYVDPPYLIT DMA_BPT2 165 105 -
GDFVYVDPPYLIT DMA_BPT4 165 105 -
GDILYLDPPYNAR MTN3_NEILA 205 139 -
ADIVYIDTPYNSR MTS1_STRSA 210 147 -
NDFIYLDPPYLIT MTS1_STRSA 540 116 -
PCLFYLDPPYRPI MT1A_MORBO 192 121 -
DSVIYCDPPYAPL DMA_HAEIN 188 112 -
GDVVYCDPPYDGT DMA7_ECOLI 173 112 -
TDIAYVDPPYNSR MTC2_CHVP1 202 135 -
DDVVYCDPPYIGR MTE5_ECOLI 187 119 -
GDIAYIDPPYTIT MTL1_LACLA 212 150 -
DTVFYFDPPYLVT MTL1_LACLA 522 113 -
SNFVFLDPPYDSV MTC1_CHVN1 171 107 -
|
| Final Motifs | Motif 1 width=17
Element Seqn Id St Int Rpt
YIGSKYKLIPFIKENIH O25809 3 3 -
YIGSKYKLIPFIKENIH O30892 3 3 -
YIGSKYKLIPFIKENIH O30889 3 3 -
YIGSKYKLIPFIKENIH O30893 3 3 -
WAGGKYPLLDDIKRHLP DMA_SALTY 10 10 -
WAGGKYPLLDDIKRHLP DMA_ECOLI 10 10 -
WAGGKYPLVDEIRRHLP DMA_SERMA 10 10 -
WTGGKRQLLPVIRELIP MT21_STRPN 17 17 -
WTGGKRQLLPHIQYLMP ML21_LACLC 17 17 -
FIGSKVNLLDNIQEVIE MTF1_FLAOK 3 3 -
YVGGKHKLLNQIVPLFP MTF1_FLAOK 371 371 -
YVGGKHKLLNQIVPLFP Q47911 371 371 -
YTGNKQSLLPELKPHFP DMA_BPT2 7 7 -
YTGNKQSLLPELKSHFP DMA_BPT4 7 7 -
YIGSKLKLSNWLETEIS MTN3_NEILA 3 3 -
WAGGKRQILHYIVSLMP O58765 8 8 -
WVGGKQKFVNNIITHFP O41063 8 8 -
YIGSKKLLLPEIKKMVD MTS1_STRSA 3 3 -
YIGGKYKLLNQILPLFP MTS1_STRSA 369 369 -
WAGGKNSLLDEIQKRLP MT1A_MORBO 7 7 -
WVGGKRQLIPEIKNLLP Q51829 22 22 -
WAGGKTQILSQIEENLP MT61_METJA 9 9 -
WAGGKFRLTDEINKAFP DMA_HAEIN 21 21 -
WAGNKTAIMSELKKHLP DMA7_ECOLI 7 7 -
YIGSKLKLKDWIFEEIS MTC2_CHVP1 6 6 -
YIGSKLKLKDWIFDEIS O37399 6 6 -
SQGIKTKLVPCIKRIVP MTE5_ECOLI 12 12 -
YIGSKLKLKDWIFEEIS Q96718 6 6 -
YLGNKTNLLNFIQQVIK MTL1_LACLA 3 3 -
YAGSKDDVIPRIFKLLP MTL1_LACLA 353 353 -
YIGNKEKIAEWICEQLP MTHA_HAEPH 11 11 -
YPGGKSKALRQILPHVP P74637 26 26 -
YQGSKRALASQILSLFP P95820 21 21 -
YPGSKWSLARQIVAEFD P71101 33 33 -
YIGNKEKIASWICDQLP O30358 10 10 -
WSGGKSDELKRFEEYIP O37398 7 7 -
WSGGKTDELKRFEDYIP MTC1_CHVN1 7 7 -
YLGSKRTLVPVLGDIAS Q56004 4 4 -
Motif 2 width=15
Element Seqn Id St Int Rpt
FCDLFAGTGIVGRAF O25809 31 11 -
FCDLFAGTGIVGRAF O30892 31 11 -
FCDLFAGTGIVGRAF O30889 31 11 -
FCDLFAGTGIVGRAF O30893 31 11 -
LVEPFVGAGSVFLNT DMA_SALTY 31 4 -
LVEPFVGAGSVFLNT DMA_ECOLI 31 4 -
LIEPFVGAGSVFLNT DMA_SERMA 31 4 -
YFEPFVGGGALFFDL MT21_STRPN 39 5 -
FFEPFIGGGALFFEP ML21_LACLC 39 5 -
FMDLFSGTGIVGENF MTF1_FLAOK 29 9 -
FVDLFSGGFNVGINV MTF1_FLAOK 393 5 -
FVDLFSGGFNVGINV Q47911 393 5 -
FVDLFCGGLSVSLNV DMA_BPT2 28 4 -
FVDLFCGGLSVSLNV DMA_BPT4 28 4 -
FCDLFAGTGIVGRKF MTN3_NEILA 31 11 -
FHEPFFGGGAVTFWL O58765 32 7 -
YHEPFLGGGSVLLAV O41063 30 5 -
FLDLFAGTNVVANYF MTS1_STRSA 29 9 -
FVDIFSGGANVGINV MTS1_STRSA 391 5 -
LVEPFVGGGAVSLWA MT1A_MORBO 33 9 -
YYEPFIGGGALLFEL Q51829 46 7 -
YIEPFVGGGAVLFYL MT61_METJA 36 10 -
LIEPFVGAGAVFLNS DMA_HAEIN 43 5 -
LVEPFAGSCAVMMAT DMA7_ECOLI 28 4 -
FADLFAGSCIMTHEA MTC2_CHVP1 32 9 -
FADLFAGSCIMTHEA O37399 32 9 -
WVEPFMGTGVVAFNV MTE5_ECOLI 35 6 -
FADLFAASCIMTHEA Q96718 32 9 -
FADLFAGTGSVGDYF MTL1_LACLA 28 8 -
FVDAMGGAFNVGANR MTL1_LACLA 375 5 -
IADVFSGGCSFSFEA MTHA_HAEPH 33 5 -
YREPFIGGGSVFLAI P74637 48 5 -
LVEPFAGSAAISVAA P95820 44 6 -
YVEPFFGSGAVFFSK P71101 54 4 -
VADVFSGGCSFAYEA O30358 32 5 -
FIEPFAGGAATFFHV O37398 29 5 -
FIEPFAGGAATFFHV MTC1_CHVN1 29 5 -
AVDLFTGTTRVAQEF Q56004 27 6 -
Motif 3 width=14
Element Seqn Id St Int Rpt
VISNDLEYYSFVLN O25809 52 6 -
VISNDLEYYSFVLN O30892 52 6 -
VISNDLEYYSFVLN O30889 52 6 -
IISNDLEYYSFVLN O30893 52 6 -
YILADINSDLISLY DMA_SALTY 50 4 -
YILADINSDLISLY DMA_ECOLI 50 4 -
YILADINSDLINLY DMA_SERMA 50 4 -
AVINDFNAELINCY MT21_STRPN 58 4 -
AVINDFNSELINCY ML21_LACLC 58 4 -
VLSNDSLYFSYILL MTF1_FLAOK 49 5 -
IIATDINTYVVEVL MTF1_FLAOK 412 4 -
IIATDINTYVVEVL Q47911 412 4 -
VLANDIQEPIIEMY DMA_BPT2 46 3 -
VLANDIQEPIIEMY DMA_BPT4 46 3 -
VIANDMEYYSYVLN MTN3_NEILA 52 6 -
GTINDINPKLINFY O58765 51 4 -
IRANDLNAYLIQTY O41063 54 9 -
VYSNDMLFFSYVNA MTS1_STRSA 49 5 -
YIFNDMNTRINEMF MTS1_STRSA 410 4 -
LVINDCNADLINVY MT1A_MORBO 57 9 -
ATINDYNEELINVY Q51829 65 4 -
VIISDINEDLMLCY MT61_METJA 59 8 -
YILADINPDLINLF DMA_HAEIN 62 4 -
YLVADINPDLINLY DMA7_ECOLI 47 4 -
CISNDLETYPYVIM MTC2_CHVP1 53 6 -
CISNDLETYSYVIL O37399 53 6 -
ALLCDTNPHLISFY MTE5_ECOLI 54 4 -
CISNDLETYSYVIM Q96718 53 6 -
VLSNDYMYFSKVIS MTL1_LACLA 48 5 -
VVYNEYHPFVFEMM MTL1_LACLA 395 5 -
VIANDILNINYQLA MTHA_HAEPH 54 6 -
YWINDLNFDLYCFW P74637 73 10 -
ALISDVNEPLMGLW P95820 67 8 -
EILNDTNGQVVNLF P71101 74 5 -
VITNDILAINYQIA O30358 53 6 -
RAISDVHTELIALY O37398 50 6 -
KVLSDVHVELVALY MTC1_CHVN1 50 6 -
VLANDVATYSEVLA Q56004 48 6 -
Motif 4 width=13
Element Seqn Id St Int Rpt
GDILYLDPPYNAR O25809 204 138 -
GDILYLDPPYNAR O30892 204 138 -
GDILYLDPPYNAR O30889 204 138 -
GDILYLDPPYNAR O30893 204 138 -
SSVVYCDPPYAPL DMA_SALTY 175 111 -
ASVVYCDPPYAPL DMA_ECOLI 175 111 -
GAVVYCDPPYAPL DMA_SERMA 175 111 -
GDFVYFDPPYIPL MT21_STRPN 188 116 -
GDFVYFDPPYIPL ML21_LACLC 188 116 -
GDILYIDPPYNGR MTF1_FLAOK 212 149 -
NDLVYCDPPYLIT MTF1_FLAOK 542 116 -
NDLVYCDPPYLIT Q47911 542 116 -
GDFVYVDPPYLIT DMA_BPT2 165 105 -
GDFVYVDPPYLIT DMA_BPT4 165 105 -
GDILYLDPPYNAR MTN3_NEILA 205 139 -
GDLVYFDPPYQPI O58765 195 130 -
HDFVYLDPPYAPE O41063 179 111 -
ADIVYIDTPYNSR MTS1_STRSA 210 147 -
NDFIYLDPPYLIT MTS1_STRSA 540 116 -
PCLFYLDPPYRPI MT1A_MORBO 192 121 -
SSFVYLDPPYHPI Q51829 193 114 -
ESFVYFDPPYKPL MT61_METJA 193 120 -
DSVIYCDPPYAPL DMA_HAEIN 188 112 -
GDVVYCDPPYDGT DMA7_ECOLI 173 112 -
TDIAYVDPPYNSR MTC2_CHVP1 202 135 -
TDIAYVDPPYNSR O37399 199 132 -
DDVVYCDPPYIGR MTE5_ECOLI 187 119 -
TDVAYVDPPYNSR Q96718 202 135 -
GDIAYIDPPYTIT MTL1_LACLA 212 150 -
DTVFYFDPPYLVT MTL1_LACLA 522 113 -
ADAVYLDPPYTGT MTHA_HAEPH 218 150 -
NVFIFLDPPYLSA P74637 194 107 -
DELVYMDPPYQGT P95820 193 112 -
NALIYADPPYLHS P71101 197 109 -
ADAVYLDPPYTGT O30358 217 150 -
DNFVFLDPPYDSV O37398 171 107 -
SNFVFLDPPYDSV MTC1_CHVN1 171 107 -
VQLMYLDPPYNQH Q56004 195 133 -
|