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PR00370

Identifier
FMOXYGENASE  [View Relations]  [View Alignment]  
Accession
PR00370
No. of Motifs
13
Creation Date
10-JUL-1995  (UPDATE 29-APR-1999)
Title
Flavin-containing monooxygenase (FMO) signature
Database References
PRINTS; PR01121 FMOXYGENASE1; PR01122 FMOXYGENASE2; PR01123 FMOXYGENASE3
PRINTS; PR01124 FMOXYGENASE4; PR01125 FMOXYGENASE5
PFAM; PF00743 FMO-like
INTERPRO; IPR000960
Literature References
1. LAWTON, M.P., CASHMAN, J.R., CRESTEIL, T., DOLPHIN, C.T., ELFARRA, A.A.,
HINES, R.N., HODGSON, E., KIMURA, T., OZOLS, J., PHILLIPS, I.R.,
PHILPOT, R.M., POULSEN, L.L., RETTIE, A.E., SHEPHARD, E.A., WILLIAMS, D.E.
AND ZIEGLER, D.M.
A nomenclature for the mammalian flavin-containing monooxygenase gene
family based on amino acid sequence identities.
ARCH.BIOCHEM.BIOPHYS. 308 (19) 254-257 (1994).
 
2. DOLPHIN, C.T., SHEPHARD, E.A., POVEY, S., PALMER, C.N.A., ZIEGLER, D.M.,
AYESH, R., SMITH, R.L. AND PHILLIPS, I.R.
Cloning, primary sequence and chromosome mapping of a human flavin-
containing monooxygenase (FMO1).
J.BIOL.CHEM. 266 12379-12385 (1991).
 
3. LAWTON, M.P., GASSER, R., TYNES, R.E., HODGSON, E. AND PHILPOT, R.M.
The flavin-containing monooxygenase enzymes expressed in rabbit liver and
lung are products of related but distinctly different genes.
J.BIOL.CHEM. 265 5855-5861 (1990).
 
4. LOMRI, N., GU, Q. AND CASHMAN, J.R.
Molecular cloning of the flavin-containing monooxygenase (FORM-II) cDNA
from adult human liver.
PROC.NATL.ACAD.SCI.U.S.A. 89 1685-1689 (1992). 
 
5. DOLPHIN, C.T., SHEPHARD, E.A., POVEY, S., SMITH, R.L. AND PHILLIPS, I. R.
Cloning, primary sequence and chromosomal localisation of human FMO2, a new
member of the flavin-containing monooxygenase family.
BIOCHEM.J. 287 261-267 (1992).
 
6. ATTA-ASAFO-ADJEI, E., LAWTON, M.P. AND PHILPOT, R.M.
Cloning, sequencing, distribution and expression in E.coli of flavin-
containing monooxygenase 1C1 - evidence for a third gene family in rabbits.
J.BIOL.CHEM. 268 9681-9689 (1993).
 
7. JOHNSTON, M., ANDREWS, S., BRINKMAN, R., COOPER, J., DING, H.,
DOVER, J., DU, Z., FAVELLO, A., FULTON, L., GATTUNG, S., GEISEL, C.,
KIRSTEN, J., KUCABA, T., HILLIER, L., JIER, M., JOHNSTON, L., LANGSTON, Y.,
LATREILLE, P., LOUIS, E.J., MACRI, C., MARDIS, E., MENEZES, S., MOUSER, L.,
NHAN, M., RIFKIN, L., RILES, L., ST.PETER, H., TREVASKIS, E., VAUGHAN, K.,
VIGNATI, D., WILCOX, L., WOHLDMAN, P., WATERSTON, R., WILSON R. AND
VAUDIN M.
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.
SCIENCE 265 2077-2082 (1994). 
 
8. STEHR, M., DIEKMANN, H., SMAU, L, SETH, O., GHISLA, S., SINGH, M. AND
MACHEROUX, P.
A hydrophobic sequence motif common to N-hydroxylating enzymes.
TRENDS BIOCHEM.SCI. 23 56-57 (1998).

Documentation
Flavin-containing monooxygenases (FMOs) constitute a family of xenobiotic-
metabolising enzymes [1]. Using an NADPH cofactor and FAD prosthetic group,
these microsomal proteins catalyse the oxygenation of nucleophilic nitrogen,
sulphur, phosphorous and selenium atoms in a range of structurally diverse
compounds. FMOs have been implicated in the metabolism of a number of
pharmaceuticals, pesticides and toxicants. In man, lack of hepatic FMO-
catalysed trimethylamine metabolism results in trimethylaminuria (fish 
odour syndrome).
 
Five mammalian forms of FMO are now known and have been designated
FMO1-FMO5 [2-6]: this is a recent nomenclature based on comparison of
amino acid sequences, and has been introduced in an attempt to eliminate
confusion inherent in multiple, laboratory-specific designations and
tissue-based classifications [1]. Following the determination of the
complete nucleotide sequence of S.cerevisiae [7], a novel gene was found
to encode a protein with similarity to mammalian monooygenases.
 
FMOXYGENASE is a 13-element fingerprint that provides a signature for
flavin-containing monooxygenases. The fingerprint was derived from an
initial alignment of 17 sequences: the motifs were drawn from conserved
regions spanning the N-terminal two-thirds of the alignment - motif 1 spans 
the region presumed to bind FAD (ADP moiety); and motif 11 includes the 
so-called FATGY motif that has also been observed in a range of siderphore 
biosynthetic enzymes [8]. Two iterations on SPTR37_9f were required to reach 
convergence, at which point a true set comprising 20 sequences was 
identified. Several partial matches were also found, largely unidentified 
sequences from the C.elegans genome project, and a tryptophan 2-mono-
oxygenase from Agrobacterium rhizogenes that matches 2 motifs.
Summary Information
  20 codes involving 13 elements
0 codes involving 12 elements
0 codes involving 11 elements
0 codes involving 10 elements
1 codes involving 9 elements
1 codes involving 8 elements
2 codes involving 7 elements
1 codes involving 6 elements
0 codes involving 5 elements
0 codes involving 4 elements
1 codes involving 3 elements
1 codes involving 2 elements
Composite Feature Index
1320202020202020202020202020
120000000000000
110000000000000
100000000000000
91111001110110
81110001011110
72222001010211
61111001000100
50000000000000
40000000000000
30000101100000
21000000000001
12345678910111213
True Positives
FMO1_HUMAN    FMO1_MOUSE    FMO1_PIG      FMO1_RABIT    
FMO1_RAT FMO2_CAVPO FMO2_MACMU FMO2_RABIT
FMO3_HUMAN FMO3_MOUSE FMO3_RABIT FMO4_HUMAN
FMO4_RABIT FMO5_CAVPO FMO5_HUMAN FMO5_MOUSE
FMO5_RABIT O60774 Q99518 YHX6_YEAST
True Positive Partials
Codes involving 9 elements
Q21310
Codes involving 8 elements
Q21311
Codes involving 7 elements
P91171 Q20730
Codes involving 6 elements
Q17585
Codes involving 3 elements
O88096
Codes involving 2 elements
TR2M_AGRRA
Sequence Titles
FMO1_HUMAN  DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 1 (EC 1.14.13.8) (FETAL HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 1) (FMO 1) (DIMETHYLANILINE OXIDASE 1) - HOMO SAPIENS (HUMAN). 
FMO1_MOUSE DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 1 (EC 1.14.13.8) (HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 1) (FMO 1) (DIMETHYLANILINE OXIDASE 1) - MUS MUSCULUS (MOUSE).
FMO1_PIG DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 1 (EC 1.14.13.8) (HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 1) (FMO 1) (DIMETHYLANILINE OXIDASE 1) - SUS SCROFA (PIG).
FMO1_RABIT DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 1 (EC 1.14.13.8) (HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 1) (FMO 1) (DIMETHYLANILINE OXIDASE 1) (FMO 1A1) (FMO FORM 1) - ORYCTOLAGUS CUNICULUS (RABBIT).
FMO1_RAT DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 1 (EC 1.14.13.8) (HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 1) (FMO 1) (DIMETHYLANILINE OXIDASE 1) - RATTUS NORVEGICUS (RAT).
FMO2_CAVPO DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 2 (EC 1.14.13.8) (PULMONARY FLAVIN-CONTAINING MONOOXYGENASE 2) (FMO 2) (DIMETHYLANILINE OXIDASE 2) (FMO 1B1) - CAVIA PORCELLUS (GUINEA PIG).
FMO2_MACMU DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 2 (EC 1.14.13.8) (PULMONARY FLAVIN-CONTAINING MONOOXYGENASE 2) (FMO 2) (DIMETHYLANILINE OXIDASE 2) (FMO 1B1) - MACACA MULATTA (RHESUS MACAQUE).
FMO2_RABIT DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 2 (EC 1.14.13.8) (PULMONARY FLAVIN-CONTAINING MONOOXYGENASE 2) (FMO 2) (DIMETHYLANILINE OXIDASE 2) (FMO 1B1) - ORYCTOLAGUS CUNICULUS (RABBIT).
FMO3_HUMAN DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 3 (EC 1.14.13.8) (HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 3) (FMO 3) (DIMETHYLANILINE OXIDASE 3) (FMO II) - HOMO SAPIENS (HUMAN).
FMO3_MOUSE DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 3 (EC 1.14.13.8) (HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 3) (FMO 3) (DIMETHYLANILINE OXIDASE 3) - MUS MUSCULUS (MOUSE).
FMO3_RABIT DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 3 (EC 1.14.13.8) (HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 3) (FMO 3) (DIMETHYLANILINE OXIDASE 3) (FMO 1D1) (FMO FORM 2) - ORYCTOLAGUS CUNICULUS (RABBIT).
FMO4_HUMAN DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 4 (EC 1.14.13.8) (HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 4) (FMO 4) (DIMETHYLANILINE OXIDASE 4) - HOMO SAPIENS (HUMAN).
FMO4_RABIT DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 4 (EC 1.14.13.8) (HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 4) (FMO 4) (DIMETHYLANILINE OXIDASE 4) (FMO 1E1) - ORYCTOLAGUS CUNICULUS (RABBIT).
FMO5_CAVPO DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 5 (EC 1.14.13.8) (HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 5) (FMO 5) (DIMETHYLANILINE OXIDASE 5) - CAVIA PORCELLUS (GUINEA PIG).
FMO5_HUMAN DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 5 (EC 1.14.13.8) (HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 5) (FMO 5) (DIMETHYLANILINE OXIDASE 5) - HOMO SAPIENS (HUMAN).
FMO5_MOUSE DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 5 (EC 1.14.13.8) (HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 5) (FMO 5) (DIMETHYLANILINE OXIDASE 5) - MUS MUSCULUS (MOUSE).
FMO5_RABIT DIMETHYLANILINE MONOOXYGENASE [N-OXIDE FORMING] 5 (EC 1.14.13.8) (HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 5) (FMO 5) (DIMETHYLANILINE OXIDASE 5) (FMO 1C1) (FMO FORM 3) - ORYCTOLAGUS CUNICULUS (RABBIT).
O60774 DJ127D3.2 (FLAVIN-CONTAINING MONOOXYGENASE FAMILY PROTEIN) - HOMO SAPIENS (HUMAN).
Q99518 FLAVIN-CONTAINING MONOOXYGENASE 2 - HOMO SAPIENS (HUMAN).
YHX6_YEAST HYPOTHETICAL 42.4 KD PROTEIN IN CTR2-STB5 INTERGENIC REGION - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).

Q21310 K08C7.5 PROTEIN - CAENORHABDITIS ELEGANS.

Q21311 K08C7.2 PROTEIN - CAENORHABDITIS ELEGANS.

P91171 SIMILAR TO FLAVIN-CONTAINING MONOOXYGENASES - CAENORHABDITIS ELEGANS.
Q20730 F53F4.5 PROTEIN - CAENORHABDITIS ELEGANS.

Q17585 C01H6.4 PROTEIN - CAENORHABDITIS ELEGANS.

O88096 HYPOTHETICAL 29.3 KD PROTEIN - ESCHERICHIA COLI.

TR2M_AGRRA TRYPTOPHAN 2-MONOOXYGENASE (EC 1.13.12.3) - AGROBACTERIUM RHIZOGENES.
Scan History
OWL26_0    2  100  NSINGLE    
SPTR37_9f 2 120 NSINGLE
Initial Motifs
Motif 1  width=17
Element Seqn Id St Int Rpt
KKVAVIGAGVSGLISLK FMO2_MACMU 2 2 -
KRVAVIGAGASGLACIK FMO5_RABIT 3 3 -
KRIAVIGGGVSGLSSIK FMO5_CAVPO 3 3 -
KKVAVIGAGVSGLISLK FMO2_CAVPO 2 2 -
KRVAIVGAGVSGLASIK FMO1_PIG 2 2 -
KKVAVIGAGVSGLISLK FMO2_RABIT 2 2 -
KRIAVIGGGVSGLSSIK FMO5_HUMAN 3 3 -
KRIAVIGAGASGLTCIK FMO5_MOUSE 3 3 -
KRVAIVGAGVSGLASIK FMO1_HUMAN 2 2 -
KRVAIVGAGVSGLASIK FMO1_RABIT 2 2 -
KRVAIVGAGVSGLASIK FMO1_MOUSE 3 3 -
KRVAIVGAGVSGLASIK FMO1_RAT 3 3 -
KKVAIIGAGISGLASIR FMO3_RABIT 2 2 -
KKVAIIGAGVSGLASIR FMO3_HUMAN 2 2 -
KKVAIIGAGVSGLAAIR FMO3_MOUSE 3 3 -
KKVAVIGAGVSGLSSIK FMO4_HUMAN 2 2 -
KKVAVIGAGVSGLTSIK FMO4_RABIT 2 2 -

Motif 2 width=25
Element Seqn Id St Int Rpt
EPTCFERTEDIGGVWRFKEKVEDGR FMO2_MACMU 26 7 -
EPVCFERTDDIGGLWRFQESPDEGR FMO5_RABIT 27 7 -
EPVCFERSADIGGLWRFQENPEEGR FMO5_CAVPO 27 7 -
EPTCFERTEDIGGLWRFKENVEDGR FMO2_CAVPO 26 7 -
EPTCFERSDDLGGLWRFTEHVEEGR FMO1_PIG 26 7 -
EPTCFERTEDIGGLWRFKENVEDGR FMO2_RABIT 26 7 -
EPVCFERTDDIGGLWRFQENPEEGR FMO5_HUMAN 27 7 -
EPVCFERSGDIGGLWRFQEAPEEGR FMO5_MOUSE 27 7 -
EPTCFERSDDLGGLWRFTEHVEEGR FMO1_HUMAN 26 7 -
EPTCFERSDDLGGLWRFTEHVEEGR FMO1_RABIT 26 7 -
EPTCFERSSDLGGLWRFTEHVEEGR FMO1_MOUSE 27 7 -
EPTCFERSCDLGGLWRFTEHVEEGR FMO1_RAT 27 7 -
EPTCFEMSDDIGGLWKFSDHAEEGR FMO3_RABIT 26 7 -
EPTCFEKSNDIGGLWKFSDHAEEGR FMO3_HUMAN 26 7 -
EPTCFERSDDVGGLWKFSDHIEEGR FMO3_MOUSE 27 7 -
EPTCFERSDDIGGLWKFTESSKDGM FMO4_HUMAN 26 7 -
EPTCFERSNDIGGLWKYTETSKDGM FMO4_RABIT 26 7 -

Motif 3 width=19
Element Seqn Id St Int Rpt
YQSVVTNTSKEMSCFSDFP FMO2_MACMU 54 3 -
YKSVIINTSKEMMCFSDYP FMO5_RABIT 55 3 -
YKSVIINTSKEMMCFSDYP FMO5_CAVPO 55 3 -
YKSVITNTSKEMSCFSDFP FMO2_CAVPO 54 3 -
YKSVVSNSCKEMSCYPDFP FMO1_PIG 54 3 -
YQSVITNTSKEMSCFSDFP FMO2_RABIT 54 3 -
YKSVIINTSKEMMCFSDYP FMO5_HUMAN 55 3 -
YQSVVINTSKEMMCFSDYP FMO5_MOUSE 55 3 -
YKSVVSNSCKEMSCYSDFP FMO1_HUMAN 54 3 -
YKSVVSNSCKEMSCYSDFP FMO1_RABIT 54 3 -
YKSVVSNSSREMSCYPDFP FMO1_MOUSE 55 3 -
YNSVVSNSSKEMSCYSDFP FMO1_RAT 55 3 -
YQSVFTNSSKEMMCFPDFP FMO3_RABIT 54 3 -
YKSVFSNSSKEMMCFPDFP FMO3_HUMAN 54 3 -
YQSVFTNSSKEMMCFPDFP FMO3_MOUSE 55 3 -
YKSLVTNVCKEMSCYSDFP FMO4_HUMAN 54 3 -
YWSLVTNVCKEMSCYSDFP FMO4_RABIT 54 3 -

Motif 4 width=16
Element Seqn Id St Int Rpt
PNFLHNSKLLEYFRIF FMO2_MACMU 78 5 -
PNFMHNSQVLEYFRMY FMO5_RABIT 79 5 -
PNFMHNSHVLEYFRMY FMO5_CAVPO 79 5 -
PNFLHNSKLLEYFRLF FMO2_CAVPO 78 5 -
PNYVPNSHFLEYLRMY FMO1_PIG 78 5 -
PNFLHNSKLLEYFRIF FMO2_RABIT 78 5 -
PNFMHNAQVLEYFRMY FMO5_HUMAN 79 5 -
PNYMHNSQVLEYFRMY FMO5_MOUSE 79 5 -
PNYVPNSQFLEYLKMY FMO1_HUMAN 78 5 -
PNYVPNSQFLDYLKMY FMO1_RABIT 78 5 -
PNFVPNSLFLEYLKLY FMO1_MOUSE 79 5 -
PNFVPNSLFLEYLQLY FMO1_RAT 79 5 -
PNFMHNSKLQEYITTF FMO3_RABIT 78 5 -
PNFMHNSKIQEYIIAF FMO3_HUMAN 78 5 -
PNFMHHSKLQEYITSF FMO3_MOUSE 79 5 -
PNFMNHEKFWDYLQEF FMO4_HUMAN 78 5 -
PNFMSHSKFWNYLQEF FMO4_RABIT 78 5 -

Motif 5 width=13
Element Seqn Id St Int Rpt
IQFQTTVLSVRKC FMO2_MACMU 103 9 -
IQFKTTVCSVKKR FMO5_RABIT 104 9 -
IQFKTTVCNVKKR FMO5_CAVPO 104 9 -
IQFQTTVLTVKKH FMO2_CAVPO 103 9 -
IQFKTKVCSVTKH FMO1_PIG 103 9 -
IQFQTTVISVKKR FMO2_RABIT 103 9 -
IRFKTTVCSVKKQ FMO5_HUMAN 104 9 -
IQFKTTVCSVKKQ FMO5_MOUSE 104 9 -
IQFKTKVCSVTKC FMO1_HUMAN 103 9 -
IQFKTTVFSITKC FMO1_RABIT 103 9 -
IYFNTKVCSITKR FMO1_MOUSE 104 9 -
IYFNTKVCSITKR FMO1_RAT 104 9 -
IQFKTLVSSIKKH FMO3_RABIT 103 9 -
IQFKTFVSSVNKH FMO3_HUMAN 103 9 -
IQFETPVTSINKC FMO3_MOUSE 104 9 -
IQFKTTVCSITKR FMO4_HUMAN 103 9 -
IQFKTTVCSVTKR FMO4_RABIT 103 9 -

Motif 6 width=17
Element Seqn Id St Int Rpt
QWKVVTQSNGKEQSAVF FMO2_MACMU 123 7 -
QWEVLTECEGKKESAVF FMO5_RABIT 124 7 -
QWEVVTEHEGKTKVDVF FMO5_CAVPO 124 7 -
QWEVVTQSDGKEQSAVF FMO2_CAVPO 123 7 -
QWDVVTLCEGKQESAVF FMO1_PIG 123 7 -
QWEVVTQSNSKQQSAVF FMO2_RABIT 123 7 -
QWEVVTESEGKKEMNVF FMO5_HUMAN 124 7 -
QWQVVTECEGKQQVDVF FMO5_MOUSE 124 7 -
QWEVVTMHEEKQESAIF FMO1_HUMAN 123 7 -
QWEVVTLHEGKQESAIF FMO1_RABIT 123 7 -
QWEVVTVTNGKQNSAIF FMO1_MOUSE 124 7 -
QWEVVTVCQGKQSSDTF FMO1_RAT 124 7 -
QWYVSTERNGKKETAVF FMO3_RABIT 123 7 -
QWDVTTERDGKKESAVF FMO3_HUMAN 123 7 -
KWEVTTEKHGKKETAVF FMO3_MOUSE 124 7 -
QWDVVTETEGKQNRAVF FMO4_HUMAN 123 7 -
QWDVVTETEGKQHRAVF FMO4_RABIT 123 7 -

Motif 7 width=17
Element Seqn Id St Int Rpt
FDAVMVCTGHHFLPHIP FMO2_MACMU 139 -1 -
FDGVLVCTGHHTSAHLP FMO5_RABIT 140 -1 -
FDAVMVCTGHHTNAHLP FMO5_CAVPO 140 -1 -
FDAVMVCSGHHILPHIP FMO2_CAVPO 139 -1 -
FDAVMVCTGFLTNPYLP FMO1_PIG 139 -1 -
FDAVMVCSGHHILPNIP FMO2_RABIT 139 -1 -
FDGVMVCTGHHTNAHLP FMO5_HUMAN 140 -1 -
FDGVLVCTGHHTDAHLP FMO5_MOUSE 140 -1 -
FDAVMVCTGFLTNPYLP FMO1_HUMAN 139 -1 -
FDAVMVCTGFLTNPHLP FMO1_RABIT 139 -1 -
FDAVMVCTGFLTNPHLP FMO1_MOUSE 140 -1 -
FAAVMVCTGFLTNPHLP FMO1_RAT 140 -1 -
FDAVMICSGHHVYPNLP FMO3_RABIT 139 -1 -
FDAVMVCSGHHVYPNLP FMO3_HUMAN 139 -1 -
FDATMICSGHHIFPHVP FMO3_MOUSE 140 -1 -
FDAVMVCTGHFLNPHLP FMO4_HUMAN 139 -1 -
FDAVMVCTGKFLNPRLP FMO4_RABIT 139 -1 -

Motif 8 width=15
Element Seqn Id St Int Rpt
FHSRQYKHPDGFEGK FMO2_MACMU 170 14 -
LHSRDYKNPEKFTGK FMO5_RABIT 171 14 -
FHSRDYKNPEAFTGK FMO5_CAVPO 171 14 -
FHSRQYKHPAGFEGK FMO2_CAVPO 170 14 -
FHSRQYKHPDIFKDK FMO1_PIG 170 14 -
FHSRQYKHPAGLEGK FMO2_RABIT 170 14 -
FHSRDYKNPEGFTGK FMO5_HUMAN 171 14 -
FHSRDYKNPVEFTGK FMO5_MOUSE 171 14 -
FHSRQYKHPDIFKDK FMO1_HUMAN 170 14 -
FHSRQYKHPDIFKDK FMO1_RABIT 170 14 -
FHSRQYKHPDIFKDK FMO1_MOUSE 171 14 -
FHSRQYKHPDVFKDK FMO1_RAT 171 14 -
FHSREYKEPGIFKGK FMO3_RABIT 170 14 -
FHSRDYKEPGVFNGK FMO3_HUMAN 170 14 -
FHSRDYKEPGIWKGK FMO3_MOUSE 171 14 -
LHSQEYKIPEGFQGK FMO4_HUMAN 170 14 -
LHCQEYKIPEGFRGQ FMO4_RABIT 170 14 -

Motif 9 width=16
Element Seqn Id St Int Rpt
DIAVELSKSAAQVFIS FMO2_MACMU 197 12 -
DLAVEISHTAKQVFLS FMO5_RABIT 198 12 -
DLAVEISHTAKQVFLS FMO5_CAVPO 198 12 -
DIASELSKNAAQVFIS FMO2_CAVPO 197 12 -
DIAVEASHLAKKVFLS FMO1_PIG 197 12 -
DIAVELSKKAAQVYIS FMO2_RABIT 197 12 -
DLAVEISQTAKQVFLS FMO5_HUMAN 198 12 -
DLAVEISHTAKQVFLS FMO5_MOUSE 198 12 -
DIAVEASHLAEKVFLS FMO1_HUMAN 197 12 -
DIAVEASHVAKKVFLS FMO1_RABIT 197 12 -
DIAVEASHLAKKVFLS FMO1_MOUSE 198 12 -
DIAVEASHLAKKVFLS FMO1_RAT 198 12 -
DIATELSHTAEQVVIS FMO3_RABIT 197 12 -
DIATELSRTAEQVMIS FMO3_HUMAN 197 12 -
DIAAELSHVAQKVTIS FMO3_MOUSE 198 12 -
DIAVELSRTAAQVLLS FMO4_HUMAN 197 12 -
DVAVELSRVAAQVLLS FMO4_RABIT 197 12 -

Motif 10 width=18
Element Seqn Id St Int Rpt
AIKVKSTVKELTETSAIF FMO2_MACMU 295 82 -
SVKIKGNVKEFTETAAIF FMO5_RABIT 296 82 -
MVKVKGNVKEFTETAAIF FMO5_CAVPO 296 82 -
AVKVKSRVTQLTETSALF FMO2_CAVPO 295 82 -
KVLIKPSIKEVKENSVVF FMO1_PIG 295 82 -
TIKVKRRVKELTESAAIF FMO2_RABIT 295 82 -
LVKVKGNVKEFTETAAIF FMO5_HUMAN 296 82 -
LVKVKGNVKEFTETAAIF FMO5_MOUSE 296 82 -
KVFIRPSIKEVKENSVIF FMO1_HUMAN 295 82 -
KVFIRPSIKEVKENSVVF FMO1_RABIT 295 82 -
KVFIKPSIKEVKENSVVF FMO1_MOUSE 296 82 -
KVLIKPSIKEVKENSVVF FMO1_RAT 296 82 -
TVSIKPNVKEFTETSAIF FMO3_RABIT 295 82 -
IVSVKPNVKEFTETSAIF FMO3_HUMAN 295 82 -
MVTIKPNVKEFTETSAVF FMO3_MOUSE 296 82 -
AITMKTSVIEFTETSAVF FMO4_HUMAN 294 81 -
TVTVKTSVKEFTETSAIF FMO4_RABIT 294 81 -

Motif 11 width=28
Element Seqn Id St Int Rpt
DGTVEENIDVIIFATGYSFSFPFLEDSL FMO2_MACMU 314 1 -
DGSREDDIDAVIFATGYSFSFPFLEDSV FMO5_RABIT 315 1 -
DGSREDDIDAVIFATGYSFDFPFLEDSV FMO5_CAVPO 315 1 -
DGTVEEDIDVIVFATGYTFSFPFLEESL FMO2_CAVPO 314 1 -
SSPEEEPIDIIVFATGYTFAFPFLDESV FMO1_PIG 314 1 -
DGTVEEDIDVIVFATGYTFAFPFLEESL FMO2_RABIT 314 1 -
DGSREDDIDAVIFATGYSFDFPFLEDSV FMO5_HUMAN 315 1 -
DGSREDGIDVVIFATGYSFAFPFLEDSV FMO5_MOUSE 315 1 -
NTSKEEPIDIIVFATGYTFAFPFLDESV FMO1_HUMAN 314 1 -
NTPSEEPIDVIVFATGYTFAFPFLDESV FMO1_RABIT 317 4 -
NTPKEEPIDIIVFATGYTFAFPFLDESV FMO1_MOUSE 315 1 -
NTPKEEPIDVIVFATGYSFAFPFLDESI FMO1_RAT 315 1 -
DGTVFEAIDSVIFATGYGYAYPFLDDSI FMO3_RABIT 314 1 -
DGTIFEGIDCVIFATGYSFAYPFLDESI FMO3_HUMAN 314 1 -
DGTMFEAIDCVIFATGYGYAYPFLDDSI FMO3_MOUSE 315 1 -
DGTVEENIDVVIFTTGYTFSFPFFEEPL FMO4_HUMAN 313 1 -
DGTVEENIDSVIFTTGYVFSFPFLEEPL FMO4_RABIT 313 1 -

Motif 12 width=18
Element Seqn Id St Int Rpt
KSTFACIGLIQPLGSIFP FMO2_MACMU 362 20 -
KPTLAIIGLIQPLGAIMP FMO5_RABIT 362 19 -
RPTLAIIGLIQPLGAIMP FMO5_CAVPO 362 19 -
KPTLTCMGLIQPLGSIFP FMO2_CAVPO 362 20 -
KPTLAVIGLIKPLGSLLP FMO1_PIG 362 20 -
KSTFACLGLIQPLGSIFP FMO2_RABIT 362 20 -
RPTLAIIGLIQPLGAIMP FMO5_HUMAN 362 19 -
KPTLAIIGLIQPLGAIMP FMO5_MOUSE 362 19 -
KPTLAIIGLIKPLGSMIP FMO1_HUMAN 362 20 -
KPTLAVIGLIKPLGSMLP FMO1_RABIT 365 20 -
KPTLAVIGLIKPLGSMVP FMO1_MOUSE 363 20 -
KPTLAVIGLIKPLGSMIP FMO1_RAT 363 20 -
KPTMAVIGLVQSLGAAIP FMO3_RABIT 362 20 -
KSTIAVIGFVQSLGAAIP FMO3_HUMAN 362 20 -
KPTMAVIGLVQSLGATIP FMO3_MOUSE 363 20 -
RATLAIIGLIGLKGSILS FMO4_HUMAN 361 20 -
RASMAIIGLISLKGSILT FMO4_RABIT 361 20 -

Motif 13 width=14
Element Seqn Id St Int Rpt
PTAELQARWVTRVF FMO2_MACMU 379 -1 -
PISELQARWATLVF FMO5_RABIT 379 -1 -
PISELQGRWAVQVF FMO5_CAVPO 379 -1 -
PTVELQARWATRVF FMO2_CAVPO 379 -1 -
PTGDTQARWAVRVL FMO1_PIG 379 -1 -
PTVELQARWATRVF FMO2_RABIT 379 -1 -
PISELQGRWATQVF FMO5_HUMAN 379 -1 -
PISELQGRWATQVF FMO5_MOUSE 379 -1 -
PTGETQARWAVRVL FMO1_HUMAN 379 -1 -
PTGETQARYTVQVF FMO1_RABIT 382 -1 -
PTGETQARWVVQVL FMO1_MOUSE 380 -1 -
PTGETQARWVVQVL FMO1_RAT 380 -1 -
PTTDLQARWAAQVI FMO3_RABIT 379 -1 -
PTVDLQSRWAAQVI FMO3_HUMAN 379 -1 -
PITDLQARWAAQVI FMO3_MOUSE 380 -1 -
SGTELQARWVTRVF FMO4_HUMAN 378 -1 -
TGTELQARWATRVF FMO4_RABIT 378 -1 -
Final Motifs
Motif 1  width=17
Element Seqn Id St Int Rpt
KKVAVIGAGVSGLISLK Q99518 3 3 -
KKVAVIGAGVSGLISLK FMO2_MACMU 2 2 -
KRVAVIGAGASGLACIK FMO5_RABIT 3 3 -
KRIAVIGGGVSGLSSIK FMO5_CAVPO 3 3 -
KKVAVIGAGVSGLISLK FMO2_CAVPO 2 2 -
KRVAIVGAGVSGLASIK FMO1_PIG 2 2 -
KKVAVIGAGVSGLISLK FMO2_RABIT 2 2 -
KRIAVIGGGVSGLSSIK FMO5_HUMAN 3 3 -
KRIAVIGAGASGLTCIK FMO5_MOUSE 3 3 -
KRVAIVGAGVSGLASIK FMO1_HUMAN 2 2 -
KRVAIVGAGVSGLASIK FMO1_RABIT 2 2 -
KRVAIVGAGVSGLASIK FMO1_MOUSE 3 3 -
KRVAIVGAGVSGLASIK FMO1_RAT 3 3 -
KKVAIIGAGISGLASIR FMO3_RABIT 2 2 -
KKVAIIGAGVSGLASIR FMO3_HUMAN 2 2 -
KRVGIIGAGVSGLAAIW O60774 3 3 -
KKVAIIGAGVSGLAAIR FMO3_MOUSE 3 3 -
KKVAVIGAGVSGLSSIK FMO4_HUMAN 2 2 -
KKVAVIGAGVSGLTSIK FMO4_RABIT 2 2 -
KRLAIIGGGPGGLAAAR YHX6_YEAST 7 7 -

Motif 2 width=25
Element Seqn Id St Int Rpt
EPTCFERTEDIGGVWRFKENVEDGR Q99518 27 7 -
EPTCFERTEDIGGVWRFKEKVEDGR FMO2_MACMU 26 7 -
EPVCFERTDDIGGLWRFQESPDEGR FMO5_RABIT 27 7 -
EPVCFERSADIGGLWRFQENPEEGR FMO5_CAVPO 27 7 -
EPTCFERTEDIGGLWRFKENVEDGR FMO2_CAVPO 26 7 -
EPTCFERSDDLGGLWRFTEHVEEGR FMO1_PIG 26 7 -
EPTCFERTEDIGGLWRFKENVEDGR FMO2_RABIT 26 7 -
EPVCFERTDDIGGLWRFQENPEEGR FMO5_HUMAN 27 7 -
EPVCFERSGDIGGLWRFQEAPEEGR FMO5_MOUSE 27 7 -
EPTCFERSDDLGGLWRFTEHVEEGR FMO1_HUMAN 26 7 -
EPTCFERSDDLGGLWRFTEHVEEGR FMO1_RABIT 26 7 -
EPTCFERSSDLGGLWRFTEHVEEGR FMO1_MOUSE 27 7 -
EPTCFERSCDLGGLWRFTEHVEEGR FMO1_RAT 27 7 -
EPTCFEMSDDIGGLWKFSDHAEEGR FMO3_RABIT 26 7 -
EPTCFEKSNDIGGLWKFSDHAEEGR FMO3_HUMAN 26 7 -
EPTCFERSDDVGGLWKFSDHTEEGR O60774 27 7 -
EPTCFERSDDVGGLWKFSDHIEEGR FMO3_MOUSE 27 7 -
EPTCFERSDDIGGLWKFTESSKDGM FMO4_HUMAN 26 7 -
EPTCFERSNDIGGLWKYTETSKDGM FMO4_RABIT 26 7 -
EIEIFVKDYDIGGVWHYPEQKSDGR YHX6_YEAST 33 9 -

Motif 3 width=19
Element Seqn Id St Int Rpt
YQSVVTNTSKEMSCFSDFP Q99518 55 3 -
YQSVVTNTSKEMSCFSDFP FMO2_MACMU 54 3 -
YKSVIINTSKEMMCFSDYP FMO5_RABIT 55 3 -
YKSVIINTSKEMMCFSDYP FMO5_CAVPO 55 3 -
YKSVITNTSKEMSCFSDFP FMO2_CAVPO 54 3 -
YKSVVSNSCKEMSCYPDFP FMO1_PIG 54 3 -
YQSVITNTSKEMSCFSDFP FMO2_RABIT 54 3 -
YKSVIINTSKEMMCFSDYP FMO5_HUMAN 55 3 -
YQSVVINTSKEMMCFSDYP FMO5_MOUSE 55 3 -
YKSVVSNSCKEMSCYSDFP FMO1_HUMAN 54 3 -
YKSVVSNSCKEMSCYSDFP FMO1_RABIT 54 3 -
YKSVVSNSSREMSCYPDFP FMO1_MOUSE 55 3 -
YNSVVSNSSKEMSCYSDFP FMO1_RAT 55 3 -
YQSVFTNSSKEMMCFPDFP FMO3_RABIT 54 3 -
YKSVFSNSSKEMMCFPDFP FMO3_HUMAN 54 3 -
YQSVFTNSSKEMMCFPDFP O60774 55 3 -
YQSVFTNSSKEMMCFPDFP FMO3_MOUSE 55 3 -
YKSLVTNVCKEMSCYSDFP FMO4_HUMAN 54 3 -
YWSLVTNVCKEMSCYSDFP FMO4_RABIT 54 3 -
YDHLETNISKKLMQFSGFP YHX6_YEAST 60 2 -

Motif 4 width=16
Element Seqn Id St Int Rpt
PNFLHNSKLLEYFRIF Q99518 79 5 -
PNFLHNSKLLEYFRIF FMO2_MACMU 78 5 -
PNFMHNSQVLEYFRMY FMO5_RABIT 79 5 -
PNFMHNSHVLEYFRMY FMO5_CAVPO 79 5 -
PNFLHNSKLLEYFRLF FMO2_CAVPO 78 5 -
PNYVPNSHFLEYLRMY FMO1_PIG 78 5 -
PNFLHNSKLLEYFRIF FMO2_RABIT 78 5 -
PNFMHNAQVLEYFRMY FMO5_HUMAN 79 5 -
PNYMHNSQVLEYFRMY FMO5_MOUSE 79 5 -
PNYVPNSQFLEYLKMY FMO1_HUMAN 78 5 -
PNYVPNSQFLDYLKMY FMO1_RABIT 78 5 -
PNFVPNSLFLEYLKLY FMO1_MOUSE 79 5 -
PNFVPNSLFLEYLQLY FMO1_RAT 79 5 -
PNFMHNSKLQEYITTF FMO3_RABIT 78 5 -
PNFMHNSKIQEYIIAF FMO3_HUMAN 78 5 -
PNYIHHSKLQEYIKTY O60774 79 5 -
PNFMHHSKLQEYITSF FMO3_MOUSE 79 5 -
PNFMNHEKFWDYLQEF FMO4_HUMAN 78 5 -
PNFMSHSKFWNYLQEF FMO4_RABIT 78 5 -
PLYPSRRNIWEYLKAY YHX6_YEAST 84 5 -

Motif 5 width=13
Element Seqn Id St Int Rpt
IQFQTTVLSVRKC Q99518 104 9 -
IQFQTTVLSVRKC FMO2_MACMU 103 9 -
IQFKTTVCSVKKR FMO5_RABIT 104 9 -
IQFKTTVCNVKKR FMO5_CAVPO 104 9 -
IQFQTTVLTVKKH FMO2_CAVPO 103 9 -
IQFKTKVCSVTKH FMO1_PIG 103 9 -
IQFQTTVISVKKR FMO2_RABIT 103 9 -
IRFKTTVCSVKKQ FMO5_HUMAN 104 9 -
IQFKTTVCSVKKQ FMO5_MOUSE 104 9 -
IQFKTKVCSVTKC FMO1_HUMAN 103 9 -
IQFKTTVFSITKC FMO1_RABIT 103 9 -
IYFNTKVCSITKR FMO1_MOUSE 104 9 -
IYFNTKVCSITKR FMO1_RAT 104 9 -
IQFKTLVSSIKKH FMO3_RABIT 103 9 -
IQFKTFVSSVNKH FMO3_HUMAN 103 9 -
IQFETLVSGIKKC O60774 104 9 -
IQFETPVTSINKC FMO3_MOUSE 104 9 -
IQFKTTVCSITKR FMO4_HUMAN 103 9 -
IQFKTTVCSVTKR FMO4_RABIT 103 9 -
IHFSTEVTYLKKK YHX6_YEAST 112 12 -

Motif 6 width=17
Element Seqn Id St Int Rpt
QWKVVTQSNGKEQSAVF Q99518 124 7 -
QWKVVTQSNGKEQSAVF FMO2_MACMU 123 7 -
QWEVLTECEGKKESAVF FMO5_RABIT 124 7 -
QWEVVTEHEGKTKVDVF FMO5_CAVPO 124 7 -
QWEVVTQSDGKEQSAVF FMO2_CAVPO 123 7 -
QWDVVTLCEGKQESAVF FMO1_PIG 123 7 -
QWEVVTQSNSKQQSAVF FMO2_RABIT 123 7 -
QWEVVTESEGKKEMNVF FMO5_HUMAN 124 7 -
QWQVVTECEGKQQVDVF FMO5_MOUSE 124 7 -
QWEVVTMHEEKQESAIF FMO1_HUMAN 123 7 -
QWEVVTLHEGKQESAIF FMO1_RABIT 123 7 -
QWEVVTVTNGKQNSAIF FMO1_MOUSE 124 7 -
QWEVVTVCQGKQSSDTF FMO1_RAT 124 7 -
QWYVSTERNGKKETAVF FMO3_RABIT 123 7 -
QWDVTTERDGKKESAVF FMO3_HUMAN 123 7 -
QWVVVTEKDGKQESTIF O60774 124 7 -
KWEVTTEKHGKKETAVF FMO3_MOUSE 124 7 -
QWDVVTETEGKQNRAVF FMO4_HUMAN 123 7 -
QWDVVTETEGKQHRAVF FMO4_RABIT 123 7 -
QWEITSKDELRTTKSDF YHX6_YEAST 127 2 -

Motif 7 width=17
Element Seqn Id St Int Rpt
FDAVMVCSGHHILPHIP Q99518 140 -1 -
FDAVMVCTGHHFLPHIP FMO2_MACMU 139 -1 -
FDGVLVCTGHHTSAHLP FMO5_RABIT 140 -1 -
FDAVMVCTGHHTNAHLP FMO5_CAVPO 140 -1 -
FDAVMVCSGHHILPHIP FMO2_CAVPO 139 -1 -
FDAVMVCTGFLTNPYLP FMO1_PIG 139 -1 -
FDAVMVCSGHHILPNIP FMO2_RABIT 139 -1 -
FDGVMVCTGHHTNAHLP FMO5_HUMAN 140 -1 -
FDGVLVCTGHHTDAHLP FMO5_MOUSE 140 -1 -
FDAVMVCTGFLTNPYLP FMO1_HUMAN 139 -1 -
FDAVMVCTGFLTNPHLP FMO1_RABIT 139 -1 -
FDAVMVCTGFLTNPHLP FMO1_MOUSE 140 -1 -
FAAVMVCTGFLTNPHLP FMO1_RAT 140 -1 -
FDAVMICSGHHVYPNLP FMO3_RABIT 139 -1 -
FDAVMVCSGHHVYPNLP FMO3_HUMAN 139 -1 -
FDAVMICSGHHVYPNLP O60774 140 -1 -
FDATMICSGHHIFPHVP FMO3_MOUSE 140 -1 -
FDAVMVCTGHFLNPHLP FMO4_HUMAN 139 -1 -
FDAVMVCTGKFLNPRLP FMO4_RABIT 139 -1 -
FDFVIVASGHYSVPKLP YHX6_YEAST 143 -1 -

Motif 8 width=15
Element Seqn Id St Int Rpt
FHSRQYKHPDGFEGK Q99518 171 14 -
FHSRQYKHPDGFEGK FMO2_MACMU 170 14 -
LHSRDYKNPEKFTGK FMO5_RABIT 171 14 -
FHSRDYKNPEAFTGK FMO5_CAVPO 171 14 -
FHSRQYKHPAGFEGK FMO2_CAVPO 170 14 -
FHSRQYKHPDIFKDK FMO1_PIG 170 14 -
FHSRQYKHPAGLEGK FMO2_RABIT 170 14 -
FHSRDYKNPEGFTGK FMO5_HUMAN 171 14 -
FHSRDYKNPVEFTGK FMO5_MOUSE 171 14 -
FHSRQYKHPDIFKDK FMO1_HUMAN 170 14 -
FHSRQYKHPDIFKDK FMO1_RABIT 170 14 -
FHSRQYKHPDIFKDK FMO1_MOUSE 171 14 -
FHSRQYKHPDVFKDK FMO1_RAT 171 14 -
FHSREYKEPGIFKGK FMO3_RABIT 170 14 -
FHSRDYKEPGVFNGK FMO3_HUMAN 170 14 -
LHSRDYKNPEAFKGK O60774 171 14 -
FHSRDYKEPGIWKGK FMO3_MOUSE 171 14 -
LHSQEYKIPEGFQGK FMO4_HUMAN 170 14 -
LHCQEYKIPEGFRGQ FMO4_RABIT 170 14 -
FHSKDFKNCEFAREK YHX6_YEAST 175 15 -

Motif 9 width=16
Element Seqn Id St Int Rpt
DIAVELSKNAAQVFIS Q99518 198 12 -
DIAVELSKSAAQVFIS FMO2_MACMU 197 12 -
DLAVEISHTAKQVFLS FMO5_RABIT 198 12 -
DLAVEISHTAKQVFLS FMO5_CAVPO 198 12 -
DIASELSKNAAQVFIS FMO2_CAVPO 197 12 -
DIAVEASHLAKKVFLS FMO1_PIG 197 12 -
DIAVELSKKAAQVYIS FMO2_RABIT 197 12 -
DLAVEISQTAKQVFLS FMO5_HUMAN 198 12 -
DLAVEISHTAKQVFLS FMO5_MOUSE 198 12 -
DIAVEASHLAEKVFLS FMO1_HUMAN 197 12 -
DIAVEASHVAKKVFLS FMO1_RABIT 197 12 -
DIAVEASHLAKKVFLS FMO1_MOUSE 198 12 -
DIAVEASHLAKKVFLS FMO1_RAT 198 12 -
DIATELSHTAEQVVIS FMO3_RABIT 197 12 -
DIATELSRTAEQVMIS FMO3_HUMAN 197 12 -
DIAVELSRLATQVIIS O60774 198 12 -
DIAAELSHVAQKVTIS FMO3_MOUSE 198 12 -
DIAVELSRTAAQVLLS FMO4_HUMAN 197 12 -
DVAVELSRVAAQVLLS FMO4_RABIT 197 12 -
DIANQLTTVAKKVYNS YHX6_YEAST 202 12 -

Motif 10 width=18
Element Seqn Id St Int Rpt
AIKVKSTVKELTETSAIF Q99518 296 82 -
AIKVKSTVKELTETSAIF FMO2_MACMU 295 82 -
SVKIKGNVKEFTETAAIF FMO5_RABIT 296 82 -
MVKVKGNVKEFTETAAIF FMO5_CAVPO 296 82 -
AVKVKSRVTQLTETSALF FMO2_CAVPO 295 82 -
KVLIKPSIKEVKENSVVF FMO1_PIG 295 82 -
TIKVKRRVKELTESAAIF FMO2_RABIT 295 82 -
LVKVKGNVKEFTETAAIF FMO5_HUMAN 296 82 -
LVKVKGNVKEFTETAAIF FMO5_MOUSE 296 82 -
KVFIRPSIKEVKENSVIF FMO1_HUMAN 295 82 -
KVFIRPSIKEVKENSVVF FMO1_RABIT 295 82 -
KVFIKPSIKEVKENSVVF FMO1_MOUSE 296 82 -
KVLIKPSIKEVKENSVVF FMO1_RAT 296 82 -
TVSIKPNVKEFTETSAIF FMO3_RABIT 295 82 -
IVSVKPNVKEFTETSAIF FMO3_HUMAN 295 82 -
TLSIKPSVKEFTETSAVF O60774 296 82 -
MVTIKPNVKEFTETSAVF FMO3_MOUSE 296 82 -
AITMKTSVIEFTETSAVF FMO4_HUMAN 294 81 -
TVTVKTSVKEFTETSAIF FMO4_RABIT 294 81 -
QLKAKLIETVQTIDSADW YHX6_YEAST 225 7 -

Motif 11 width=28
Element Seqn Id St Int Rpt
DGTVEENIDVIIFATGYSFSFPFLEDSL Q99518 315 1 -
DGTVEENIDVIIFATGYSFSFPFLEDSL FMO2_MACMU 314 1 -
DGSREDDIDAVIFATGYSFSFPFLEDSV FMO5_RABIT 315 1 -
DGSREDDIDAVIFATGYSFDFPFLEDSV FMO5_CAVPO 315 1 -
DGTVEEDIDVIVFATGYTFSFPFLEESL FMO2_CAVPO 314 1 -
SSPEEEPIDIIVFATGYTFAFPFLDESV FMO1_PIG 314 1 -
DGTVEEDIDVIVFATGYTFAFPFLEESL FMO2_RABIT 314 1 -
DGSREDDIDAVIFATGYSFDFPFLEDSV FMO5_HUMAN 315 1 -
DGSREDGIDVVIFATGYSFAFPFLEDSV FMO5_MOUSE 315 1 -
NTSKEEPIDIIVFATGYTFAFPFLDESV FMO1_HUMAN 314 1 -
NTPSEEPIDVIVFATGYTFAFPFLDESV FMO1_RABIT 317 4 -
NTPKEEPIDIIVFATGYTFAFPFLDESV FMO1_MOUSE 315 1 -
NTPKEEPIDVIVFATGYSFAFPFLDESI FMO1_RAT 315 1 -
DGTVFEAIDSVIFATGYGYAYPFLDDSI FMO3_RABIT 314 1 -
DGTIFEGIDCVIFATGYSFAYPFLDESI FMO3_HUMAN 314 1 -
DGTMFEAIDSVIFATGYDYSYPFLDETI O60774 315 1 -
DGTMFEAIDCVIFATGYGYAYPFLDDSI FMO3_MOUSE 315 1 -
DGTVEENIDVVIFTTGYTFSFPFFEEPL FMO4_HUMAN 313 1 -
DGTVEENIDSVIFTTGYVFSFPFLEEPL FMO4_RABIT 313 1 -
DGRVLQNIDYIIFATGYYYSFPFIEPSV YHX6_YEAST 251 8 -

Motif 12 width=18
Element Seqn Id St Int Rpt
KSTLACIGLIQPLGSIFP Q99518 363 20 -
KSTFACIGLIQPLGSIFP FMO2_MACMU 362 20 -
KPTLAIIGLIQPLGAIMP FMO5_RABIT 362 19 -
RPTLAIIGLIQPLGAIMP FMO5_CAVPO 362 19 -
KPTLTCMGLIQPLGSIFP FMO2_CAVPO 362 20 -
KPTLAVIGLIKPLGSLLP FMO1_PIG 362 20 -
KSTFACLGLIQPLGSIFP FMO2_RABIT 362 20 -
RPTLAIIGLIQPLGAIMP FMO5_HUMAN 362 19 -
KPTLAIIGLIQPLGAIMP FMO5_MOUSE 362 19 -
KPTLAIIGLIKPLGSMIP FMO1_HUMAN 362 20 -
KPTLAVIGLIKPLGSMLP FMO1_RABIT 365 20 -
KPTLAVIGLIKPLGSMVP FMO1_MOUSE 363 20 -
KPTLAVIGLIKPLGSMIP FMO1_RAT 363 20 -
KPTMAVIGLVQSLGAAIP FMO3_RABIT 362 20 -
KSTIAVIGFVQSLGAAIP FMO3_HUMAN 362 20 -
KPTLAVIGLVQSLGAAIP O60774 363 20 -
KPTMAVIGLVQSLGATIP FMO3_MOUSE 363 20 -
RATLAIIGLIGLKGSILS FMO4_HUMAN 361 20 -
RASMAIIGLISLKGSILT FMO4_RABIT 361 20 -
KDPTLSFILTPQLVIPFP YHX6_YEAST 308 29 -

Motif 13 width=14
Element Seqn Id St Int Rpt
PTAELQARWVTRVF Q99518 380 -1 -
PTAELQARWVTRVF FMO2_MACMU 379 -1 -
PISELQARWATLVF FMO5_RABIT 379 -1 -
PISELQGRWAVQVF FMO5_CAVPO 379 -1 -
PTVELQARWATRVF FMO2_CAVPO 379 -1 -
PTGDTQARWAVRVL FMO1_PIG 379 -1 -
PTVELQARWATRVF FMO2_RABIT 379 -1 -
PISELQGRWATQVF FMO5_HUMAN 379 -1 -
PISELQGRWATQVF FMO5_MOUSE 379 -1 -
PTGETQARWAVRVL FMO1_HUMAN 379 -1 -
PTGETQARYTVQVF FMO1_RABIT 382 -1 -
PTGETQARWVVQVL FMO1_MOUSE 380 -1 -
PTGETQARWVVQVL FMO1_RAT 380 -1 -
PTTDLQARWAAQVI FMO3_RABIT 379 -1 -
PTVDLQSRWAAQVI FMO3_HUMAN 379 -1 -
PTADLQAWWAAKVF O60774 380 -1 -
PITDLQARWAAQVI FMO3_MOUSE 380 -1 -
SGTELQARWVTRVF FMO4_HUMAN 378 -1 -
TGTELQARWATRVF FMO4_RABIT 378 -1 -
PLSELQAAIMVEVF YHX6_YEAST 325 -1 -