==SPRINT==> PRINTS View

selected as

PR00359

Identifier

BP450  [View Relations]  [View Alignment]

Accession

PR00359

No. of Motifs

Creation Date

11-JUL-1995  (UPDATE 13-JUN-1999)

Title

B-class P450 signature

Database References

PRINTS; PR00385 P450
INTERPRO; IPR002397
PDB; 2CPP; 1CPT
SCOP; 2CPP; 1CPT
CATH; 2CPP; 1CPT

Literature References

1. NOMENCLATURE COMMITTEE OF THE INTERNATIONAL UNION OF BIOCHEMISTRY (NC-IUB).
Nomenclature of electron-transfer proteins. Recommendations 1989.
EUR.J.BIOCHEMISTRY 200 599-611 (1991).
 
2. NEBERT, D.W. AND GONZALEZ, F.J.
P450 genes: structure, evolution, and regulation. 
ANNU.REV.BIOCHEMISTRY 56 945-993 (1987). 
 
3. DEGTYARENKO, K.N. AND ARCHAKOV, A.I.
Molecular evolution of P450 superfamily and P450-containing monooxygenase
systems.
FEBS LETT. 332 1-8 (1993).
 
4. RUETTINGER, R.T., WEN, L.P. AND FULCO, A.J.
Coding nucleotide, 5' regulatory, and deduced amino acid sequences of 
P-450BM-3, a single peptide cytochrome P-450:NADPH-P-450 reductase from 
Bacillus megaterium. 
J.BIOL.CHEM. 264 10987-10995 (1989).
 
5. NELSON, D.R., KAMATAKI, T., WAXMAN, D.J., GUENGERICH, F.P., 
ESTABROOK, R.W., FEYEREISEN, R., GONZALEZ, F.J., COON, M.J.,   
GUNSALUS, I.C., GOTOH, O., OKUDA, K. AND NEBERT, D.W.          
The P450 superfamily: update on new sequences, gene mapping, accession 
numbers, early trivial names of enzymes, and nomenclature. 
DNA CELL BIOL. 12 1-51 (1993). 
 
6. KIZAWA, H., TOMURA, D., ODA, M., FUKAMIZU, A., HOSHINO, T., GOTOH, O.,
YASUI, T. AND SHOUN, H.
Nucleotide sequence of the unique nitrate/nitrite-inducible cytochrome 
P-450 cDNA from Fusarium oxysporum. 
J.BIOL.CHEM. 266 10632-10637 (1991). 
 
7. POULOS, T.L., FINZEL, B.C. AND HOWARD, A.J.
High-resolution crystal structure of cytochrome P450cam. 
J.MOL.BIOL. 195 687-700 (1987). 
 
8. HASEMANN, C.A., RAVICHANDRAN, K.G., PETERSON, J.A. AND DEISENHOFER, J.
Crystal structure and refinement of cytochrome P450terp at 2.3 A resolution. 
J.MOL.BIOL. 236 1169-1185 (1994). 
 
9. CUPP-VICKERY, J.R. AND POULOS, T.L. 
Structure of cytochrome P450eryF involved in erythromycin biosynthesis. 
NAT.STRUCT.BIOL. 2 144-153 (1995).

Documentation

P450 enzymes constitute a superfamily of haem-thiolate proteins [1],
widely distributed in bacteria, fungi, plants and animals. The enzymes
are involved in metabolism of a plethora of both exogenous and endogenous
compounds [2]. Usually, they act as terminal oxidases in multicomponent
electron transfer chains, called P450-containing monooxygenase systems. 
 
P450-containing monooxygenase systems primarily fall into 2 major classes:
bacterial/mitochondrial (type I), and microsomal (type II). Alternatively,
P450-containing systems can be classified according to the number of their
protein components [3]: mitochondrial and most bacterial P450 systems have
3 components - an FAD-containing flavoprotein (NADPH or NADH-dependent
reductase), an iron-sulphur protein, and P450; the eukaryotic microsomal 
P450 system contains 2 components - NADPH:P450 reductase (a flavoprotein
containing both FAD and FMN) and P450; and a soluble monooxygenase P450BM-3
from Bacillus megaterium exists as a single polypeptide chain with 2 
functional parts (the haem and flavin domains), and represents a unique 
bacterial one-component system - sequence and functional comparisons show
that these domains are more similar to P450 and the flavoprotein of the
microsomal 2-component P450 monooxygenase system than to the relevant
proteins of the 3-component system [4].
 
Current P450 nomenclature, based on divergent evolution of the P450 super-
family, was proposed and developed by Nebert et al. [5]. But evolution of
P450s is not restricted to phylogeny; phylogenetic analysis can only be
applied to certain groups of orthologous genes (e.g. CYP1A1, 1A2, 2E1, 7,
11A1, 11B1, 17, 19, 21A1, 27 and 51). Some P450 gene clusters (e.g. the
mammalian CYP1A1 and CYP1A2, rat CYP2D cluster, house fly CYP6A and CYP6C 
gene clusters, CYP13A cluster in Caenorhabditis elegans) have seemingly 
appeared via gene duplication events and should be considered paralogous.
In P450 gene subfamilies such as CYP2A, 2B, 2C, 2D, 3A, 4A and 52A, which,
presumably, have arisen through numerous species-specific gene duplication
and conversion events, orthologue assignments are impossible. This kind of
evolution can be concerned with intraspecific specialisation. Gene fusion
events can lead to the appearance of a one-component P450 system. It has
been hypothesised that the Fusarium oxysporum P450nor (CYP55) gene is a
xenologous gene of prokaryotic origin [6]. Another example of a much more
ancient horizontal gene transfer event could be the integration of former
mitochondrial genes (families CYP11 and CYP27) into the nuclear genome.
Finally, convergent evolution cannot be ignored, such as witnessed in the
membrane-binding anchors or in the substrate-binding sites of P450 enzymes
from the different families, which have similar substrate specificity. 
 
On the basis of sequence similarity, all P450s can be categorised into 2
main groups, the so-called B- and E-classes: P450 proteins of prokaryotic
3-component systems and fungal P450nor (CYP55) belong to the B-class; all
other known P450s from distinct systems are of the E-class. The data
suggest that divergence of the P450 superfamily into B- and E-classes, and
further divergence into stable P450 groups within the E-class, must be very
ancient and had occured before the appearance of eukaryotes. 
 
By contrast with the E-class, which mainly consists of multigenic families,
most families in the B-class are presented by the unique known sequence. 
Exceptions are families CYP105 (5 subfamilies), CYP107 (6 subfamilies) 
and CYP113 (2 subfamilies); only CYP105A and CYP106A subfamilies contain 
2 different genes.  
 
To date, the 3D structures of 4 P450s have been reported, 3 of which belong
to the B-class: P450cam [7], P450terp [8] and P450eryF [9]. The P450
molecule is an alpha/beta protein, shaped like a triangular prism; the
overall structure can be roughly divided into alpha-rich (`right side') and
beta-rich (`left side') domains [7-9]. However, this division appears to be
artificial since the alpha- and beta-rich domains comprise discontinuous
assemblies of secondary structure segments and do not constitute independent
folding units. Although the sequence identity between any 2 P450s with known
3D structure reaches only 20% or less, the overall topology of the proteins
is similar, with some differences in the orientations of various helices.
The most dramatic variations between P450 structures are found in regions 
responsible for substrate binding and access. 
 
BP450 is a 9-element fingerprint that provides a signature for B-class 
P450s. The fingerprint was derived from an initial alignment of 20
sequences: the motifs were drawn from the most conserved regions of the
alignment - motif 1 includes the N-terminal part of the C helix; motifs 2
and 3 are adjacent and span the E helix and the major part of the F helix;
motif 4 includes the C-terminal half of the G helix and the entire H helix;
motif 5 corresponds to the K helix (cf. motif 3 of signature P450); motifs
6 and 7 span strands 3 and 4, the 3-10 helix of P450cam (the K' helix in
P450 terp [8]) and the neighbouring loop region; motifs 8 and 9 are
adjacent, spanning the invariant Cys residue, which provides the haem iron
thiolate ligand (cf. PROSITE pattern CYTOCHROME_P450 (PS00086) and motifs
4 and 5 of signature P450) - motif 9 spans the N-terminus of the L helix
(nb. in the B-class P450s, the regions corresponding to motifs 1 and 2 of
signature P450 are not sufficiently conserved to be used in the fingerprint,
although at the structural level, the I and J helices are well conserved in
all known crystal structures [7-9]). Two iterations on OWL26.0 were required
to reach convergence, at which point a true set comprising 23 sequences was
identified. Several partial matches were also found, several of which are
P450 sequences matching 5 motifs; most of the sequences matching only 2
motifs are noise. Among the partial matches, 2 bacterial P450 sequences
were found: a hypothetical product of CYP117 gene from Bradyrhizobium
japonicum (BJU126785), matching motifs 3, 6, 8 and 9; and nitrogen fixation-
associated gene CYP110 from Anabaena sp., which matches only motifs 5 and 9.
 
An update on SPTR37_9f identified a true set of 45 sequences, and 255
partial matches.

Summary Information

  45 codes involving  9 elements
   9 codes involving  8 elements
   6 codes involving  7 elements
   5 codes involving  6 elements
   5 codes involving  5 elements
   8 codes involving  4 elements
  52 codes involving  3 elements
 170 codes involving  2 elements

Composite Feature Index

9	45	45	45	45	45	45	45	45	45
8	7	9	8	5	9	9	8	9	8
7	3	4	5	4	6	6	3	6	5
6	5	1	2	4	3	5	3	5	2
5	3	1	1	3	3	5	3	5	1
4	0	0	1	1	2	7	8	7	6
3	6	4	2	1	10	36	43	17	37
2	8	4	2	6	27	86	77	32	98
	1	2	3	4	5	6	7	8	9

True Positives

BIOI_BACSU    CPXE_STRGO    CPXF_STRGO    CPXH_STRGR    
CPXI_BACME    CPXJ_SACER    CPXK_SACER    CPXL_PSESP    
CPXM_BACME    CPXM_BACSU    CPXP_BRAJA    CPXP_RHISN    
CPXQ_SACER    CPXR_BRAJA    CPXR_RHISN    CPXY_BACSU    
FAS1_RHOFA    NOR1_CYLTO    NOR2_CYLTO    NOR_FUSOX     
O08464        O31785        O32460        O33180        
O34374        O52544        O52561        O52823        
O53563        O85697        O87192        O87605        
O87674        O87675        P71856        P77902        
Q54302        Q59523        Q59723        Q59819        
Q59831        Q59910        Q60005        YP22_MYCTU    
YU44_MYCTU

True Positive Partials

Codes involving 8 elements
CPXC_AGRT6    CPXG_STRSQ    CPXW_SULSO    O24727        
O52560        Q59921        THCB_RHOSO    Y08Q_MYCTU    
YU42_MYCTU

Codes involving 7 elements
CPXA_PSEPU    O50242        O52572        O52802        
P77977        Q59971

Codes involving 6 elements
O08362        O50243        O53936        Q59079        
Y4VG_RHISN

Codes involving 5 elements
C883_ARATH    CPXD_AGRT6    O34926        O52822        
O87673

Codes involving 4 elements
C881_MAIZE    CPN1_PIG      CPN2_MOUSE    Q54823        
Q64539        Q64546        Q64586        YU34_MYCTU

Codes involving 3 elements
AVNA_ASPPA    CP09_MYCTU    CP10_LYMST    CP2B_HUMAN    
CP2B_MOUSE    CP2B_RAT      CP36_RABIT    CP3T_PIG      
CPCB_RAT      CPCM_RAT      CPCT_MOUSE    CPCU_RABIT    
CPM1_HUMAN    CPM1_RAT      CPN1_HUMAN    CPN1_PAPHA    
CPN1_RAT      CPN2_HUMAN    CPN2_MESAU    CPN2_RAT      
CPN3_RAT      CPT7_CHICK    CPT7_ONCMY    CPT7_ORYLA    
CPT7_SQUAC    CPXU_RHISN    O08447        O13254        
O13820        O16156        O16482        O16670        
O16672        O17655        O33934        O44655        
O44658        O45317        O45659        O46515        
O54225        O65624        O69653        O81077        
O86330        O87829        P95099        Q27465        
Q27470        Q27482        THAS_PIG      THAS_RAT

Codes involving 2 elements
C2F1_HUMAN    C2F2_MOUSE    C4D1_DROME    C4D1_DROSI    
C4D2_DROME    C718_MENPI    C755_EUSGR    C756_CAMME    
C757_EUSGR    C772_SOLME    C7E1_SORBI    C823_SOYBN    
C824_SOYBN    C861_ARATH    C892_ARATH    C931_SOYBN    
C932_SOYBN    C933_SOYBN    CP18_DROME    CP27_HUMAN    
CP27_RABIT    CP27_RAT      CP31_RAT      CP33_HUMAN    
CP34_HUMAN    CP39_RAT      CP3A_MESAU    CP3C_CANFA    
CP3D_MOUSE    CP3E_CAVPO    CP3O_SHEEP    CP3R_ONCMY    
CP51_CANAL    CP51_CANGA    CP51_PENIT    CP51_SCHPO    
CP51_UNCNE    CP51_USTMA    CP74_ARATH    CP74_LINUS    
CPA3_RAT      CPA4_MOUSE    CPA5_MOUSE    CPA6_HUMAN    
CPA7_HUMAN    CPAB_RABIT    CPB9_MOUSE    CPBA_MOUSE    
CPBB_CANFA    CPC2_RABIT    CPC3_RABIT    CPC4_RABIT    
CPC5_RABIT    CPC6_RAT      CPC8_HUMAN    CPCD_RAT      
CPCG_RABIT    CPCN_RAT      CPCP_MESAU    CPCQ_MESAU    
CPD1_RAT      CPD3_RAT      CPD4_RAT      CPD5_RAT      
CPD6_HUMAN    CPD9_MOUSE    CPDA_MOUSE    CPDF_CANFA    
CPDG_CAVPO    CPDH_MACFA    CPDI_RAT      CPDJ_CALJA    
CPE1_BOVIN    CPE1_HUMAN    CPE1_MESAU    CPE1_MOUSE    
CPE1_PIG      CPE1_RABIT    CPE1_RAT      CPJ1_RABIT    
CPJ2_HUMAN    CPK1_ONCMY    CPM1_BOVIN    CPM1_CAPHI    
CPM1_ONCMY    CPM1_PIG      CPM1_SHEEP    CPN1_CAVPO    
CPN1_MESAU    CPP1_DROAC    CPS1_BOVIN    CPS1_HUMAN    
CPS1_PIG      CPS3_PIG      CPT7_ICTPU    CPT7_RANDY    
CPXN_ANASP    CPXU_BRAJA    CPZ6_CANFA    ERG5_YEAST    
HNF4_DROME    O02641        O16362        O16671        
O16673        O22185        O22188        O22744        
O23154        O23387        O23389        O23397        
O26651        O33959        O44652        O44656        
O44657        O44659        O44704        O45605        
O46051        O46053        O48786        O52819        
O58111        O61204        O61935        O62377        
O62378        O64853        O64989        O76345        
O76800        O88037        O93297        O93304        
P70983        P77900        P95746        P96813        
Q06884        Q08078        Q16741        Q16742        
Q16749        Q16753        Q16874        Q27471        
Q27506        Q29454        Q29508        Q42959        
Q43071        Q54296        Q59163        Q64460        
Q64463        Q64529        Q64530        Q64590        
Q64615        Q64639        Q92088        Q92129        
STCF_EMENI    STCL_EMENI    THAS_HUMAN    THAS_MOUSE    
TR11_FUSSP    YDAK_CAEEL

Sequence Titles

BIOI_BACSU  BIOTIN BIOSYNTHESIS; CYTOCHROME P450-LIKE ENZYME (EC 1.14.-.-) - BACILLUS SUBTILIS. 
CPXE_STRGO  CYTOCHROME P450-SU1 (EC 1.14.-.-) (P450-CVA1) (CYP105A1) - STREPTOMYCES GRISEOLUS. 
CPXF_STRGO  CYTOCHROME P450-SU2 (EC 1.14.-.-) (P450-CVB1) (CYP105B1) - STREPTOMYCES GRISEOLUS. 
CPXH_STRGR  CYTOCHROME P450-SOY (EC 1.14.-.-) - STREPTOMYCES GRISEUS. 
CPXI_BACME  CYTOCHROME P450(BM-1) (EC 1.14.14.1) - BACILLUS MEGATERIUM. 
CPXJ_SACER  6-DEOXYERYTHRONOLIDE B HYDROXYLASE (EC 1.-.-.-) (6-DEB HYDOXYLASE) (ERYTHOMYCIN A BIOSYNTHESIS HYDROLASE) (CYTOCHROME P450 107A1) (CYPCVIIA1) - SACCHAROPOLYSPORA ERYTHRAEA (STREPTOMYCES ERYTHRAEUS). 
CPXK_SACER  CYTOCHROME P450 107B1 (EC 1.14.-.-) (P450CVIIB1) - SACCHAROPOLYSPORA ERYTHRAEA (STREPTOMYCES ERYTHRAEUS). 
CPXL_PSESP  CYTOCHROME P450-TERP (EC 1.14.-.-) (CYTOCHROME P450 108) - PSEUDOMONAS SP. 
CPXM_BACME  CYTOCHROME P450(MEG) (EC 1.14.99.-) (STEROID 15-BETA-HYDROXYLASE) (STEROID 15-BETA-MONOOXYGENASE) - BACILLUS MEGATERIUM. 
CPXM_BACSU  CYTOCHROME P450 109 (EC 1.14.-.-) (ORF405) - BACILLUS SUBTILIS. 
CPXP_BRAJA  CYTOCHROME P450 BJ-1 (EC 1.14.14.-) (CYTOCHROME P450 112) - BRADYRHIZOBIUM JAPONICUM. 
CPXP_RHISN  CYTOCHROME P450 BJ-1 HOMOLOG (EC 1.14.14.-) - RHIZOBIUM SP. (STRAIN NGR234). 
CPXQ_SACER  CYTOCHROME P450 113A1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE) - SACCHAROPOLYSPORA ERYTHRAEA (STREPTOMYCES ERYTHRAEUS). 
CPXR_BRAJA  CYTOCHROME P450 BJ-3 (EC 1.14.14.-) (CYTOCHROME P450 114) - BRADYRHIZOBIUM JAPONICUM. 
CPXR_RHISN  CYTOCHROME P450 BJ-3 HOMOLOG (EC 1.14.14.-) - RHIZOBIUM SP. (STRAIN NGR234). 
CPXY_BACSU  CYTOCHROME P450 (EC 1.14.-.-) - BACILLUS SUBTILIS. 
FAS1_RHOFA  CYTOCHROME P450 FAS1 (EC 1.14.-.-) - RHODOCOCCUS FASCIANS. 
NOR1_CYLTO  CYTOCHROME P450 55A2 (EC 1.14.-.-) (CYTOCHROME P450NOR1) - CYLINDROCARPON TONKINENSE. 
NOR2_CYLTO  CYTOCHROME P450 55A3 (EC 1.14.-.-) (CYTOCHROME P450NOR2) - CYLINDROCARPON TONKINENSE. 
NOR_FUSOX   CYTOCHROME P450 55A1 (EC 1.14.-.-) (CYPLVA1) (P450 DNIR) (NITRIC-OXIDE REDUCTASE) (P450 NOR) - FUSARIUM OXYSPORUM. 
O08464      CYTOCHROME P450 (EC 1.14.14.1) - MYCOBACTERIUM TUBERCULOSIS. 
O31785      HYDROXYLASE OF THE POLYKETIDE PRODUCED BY THE PKS CLUSTER - BACILLUS SUBTILIS. 
O32460      ORF 10 - ACTINOMADURA HIBISCA.                
O33180      PROBABLE CYTOCHROME P450 - MYCOBACTERIUM TUBERCULOSIS. 
O34374      P450 HEME-THIOLATE PROTEIN - BACILLUS SUBTILIS. 
O52544      CYTOCHROME P450 MONOOXYGENASE - AMYCOLATOPSIS MEDITERRANEI. 
O52561      CYTOCHROME P450 MONOOXYGENASE - AMYCOLATOPSIS MEDITERRANEI. 
O52823      PCZA363.7 - AMYCOLATOPSIS ORIENTALIS.         
O53563      PUTATIVE CYTOCHROME P450 MONOXYGENASE - MYCOBACTERIUM TUBERCULOSIS. 
O85697      PUTATIVE CYTOCHROME P450 OXIDOREDUCTASE - STREPTOMYCES LIVIDANS. 
O87192      ORF-2 PROTEIN - STREPTOMYCES GRISEUS.         
O87605      CYTOCHROME P450 MONOOXYGENASE - STREPTOMYCES VIOLACEUS (STREPTOMYCES VENEZUELAE), AND STREPTOMYCES VENEZUELAE. 
O87674      OXYGENASE B - AMYCOLATOPSIS MEDITERRANEI.     
O87675      OXYGENASE C - AMYCOLATOPSIS MEDITERRANEI.     
P71856      HYPOTHETICAL 48.4 KD PROTEIN - MYCOBACTERIUM TUBERCULOSIS. 
P77902      PROBABLE CYTOCHROME P450 CY369.11C (EC 1.14.14.1) - MYCOBACTERIUM TUBERCULOSIS. 
Q54302      CYTOCHROME P450 - STREPTOMYCES HYGROSCOPICUS. 
Q59523      CYTOCHROME P450-LIKE PROTEIN (EC 1.14.14.1) - MICROMONOSPORA GRISEORUBIDA. 
Q59723      CYTOCHROME P450 LIN (EC 1.14.14.1) - PSEUDOMONAS INCOGNITA. 
Q59819      CYTOCHROME P450 (EC 1.14.14.1) - STREPTOMYCES ANTIBIOTICUS. 
Q59831      CYTOCHROME P450 SCA-2 (EC 1.14.14.1) - STREPTOMYCES CARBOPHILUS. 
Q59910      CYTOCHROME P450 (EC 1.14.14.1) - STREPTOMYCES FRADIAE. 
Q60005      PUTATIVE CYTOCHROME P-450 PROTEIN (EC 1.14.14.1) (UNSPECIFIC MONOOXYGENASE) (MICROSOMAL MONOOXYGENASE) (XENOBIOTIC MONOOXYGENASE) (ARYL-4-MONOOXYGENASE) (ARYL HYDROCARBON HYDROXYLASE) (MICROSOMAL P450) (FLAVOPROTEIN-LINKED MONOOXYGENASE) (CYTOCHROME P450) - STREPTOMYCES THERMOTOLERANS. 
YP22_MYCTU  PUTATIVE CYTOCHROME P450 CY369.22 (EC 1.14.-.-) - MYCOBACTERIUM TUBERCULOSIS. 
YU44_MYCTU  PUTATIVE CYTOCHROME P450 CY339.44C (EC 1.14.-.-) - MYCOBACTERIUM TUBERCULOSIS. 
 
CPXC_AGRT6  CYTOCHROME P450-PINF1, PLANT-INDUCIBLE (EC 1.14.-.-) - AGROBACTERIUM TUMEFACIENS. 
CPXG_STRSQ  CYTOCHROME P450 105C1 (EC 1.14.-.-) - STREPTOMYCES SP. 
CPXW_SULSO  PROBABLE CYTOCHROME P450 119 (EC 1.14.14.-) - SULFOLOBUS SOLFATARICUS. 
O24727      HYPOTHETICAL 43.4 KD PROTEIN - NOCARDIOIDES SP. (STRAIN KP7). 
O52560      CYTOCHROME P450 MONOOXYGENASE - AMYCOLATOPSIS MEDITERRANEI. 
Q59921      CYTOCHROME P450 (EC 1.14.14.1) - STREPTOMYCES HYGROSCOPICUS. 
THCB_RHOSO  CYTOCHROME P450 116 (EC 1.14.-.-) - RHODOCOCCUS SP. (STRAIN NI86/21). 
Y08Q_MYCTU  PUTATIVE CYTOCHROME P450 CY50.26 (EC 1.14.-.-) - MYCOBACTERIUM TUBERCULOSIS. 
YU42_MYCTU  PUTATIVE CYTOCHROME P450 CY339.42 (EC 1.14.-.-) - MYCOBACTERIUM TUBERCULOSIS. 
 
CPXA_PSEPU  CYTOCHROME P450-CAM (EC 1.14.15.1) (CAMPHOR 5-MONOOXYGENASE) - PSEUDOMONAS PUTIDA. 
O50242      P-450 MONOOXYGENASE - AGROBACTERIUM TUMEFACIENS. 
O52572      CYTOCHROME P450 MONOOXYGENASE - AMYCOLATOPSIS MEDITERRANEI. 
O52802      PCZA361.17 - AMYCOLATOPSIS ORIENTALIS.        
P77977      CYTOCHROME P450 (EC 1.14.14.1) - STREPTOMYCES SP. 
Q59971      CYTOCHROME P450 (DAUNOMYCIN C-14 HYDROXYLASE) (EC 1.14.14.1) - STREPTOMYCES SP. 
 
O08362      HYPOTHETICAL 43.7 KD PROTEIN (EC 1.14.14.1) - MYCOBACTERIUM TUBERCULOSIS. 
O50243      P-450 MONOXYGENASE - AGROBACTERIUM TUMEFACIENS. 
O53936      PUTATIVE CYTOCHROME P450 - MYCOBACTERIUM TUBERCULOSIS. 
Q59079      VITAMIN D3 25-HYDROXYLASE (EC 1.14.-.-) - AMYCOLATA AUTOTROPHICA. 
Y4VG_RHISN  PROBABLE CYTOCHROME P450 Y4VG (EC 1.14.14.-) - RHIZOBIUM SP. (STRAIN NGR234). 
 
C883_ARATH  CYTOCHROME P450 88A3 (EC 1.14.-.-) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS). 
CPXD_AGRT6  CYTOCHROME P450-PINF2, PLANT-INDUCIBLE (EC 1.14.-.-) - AGROBACTERIUM TUMEFACIENS. 
O34926      CYPB - BACILLUS SUBTILIS.                     
O52822      PCZA363.6 - AMYCOLATOPSIS ORIENTALIS.         
O87673      OXYGENASE A - AMYCOLATOPSIS MEDITERRANEI.     
 
C881_MAIZE  CYTOCHROME P450 88A1 (EC 1.14.-.-) (DWARF3 PROTEIN) - ZEA MAYS (MAIZE). 
CPN1_PIG    CYTOCHROME P450 11B1 PRECURSOR (EC 1.14.15.4) (CYPXIB1) (P450C11) (STEROID 11-BETA-HYDROXYLASE) - SUS SCROFA (PIG). 
CPN2_MOUSE  CYTOCHROME P450 11B2 PRECURSOR (EC 1.14.15.4) (CYPXIB2) (P450C11) (STEROID 11-BETA-HYDROXYLASE) (ALDOSTERONE SYNTHASE) - MUS MUSCULUS (MOUSE). 
Q54823      DNRP - STREPTOMYCES PEUCETIUS.                
Q64539      CYTOCHROME P450 11-BETA (EC 1.14.14.1) - RATTUS NORVEGICUS (RAT). 
Q64546      CYTOCHROME P450 C11B3 (EC 1.14.14.1) - RATTUS NORVEGICUS (RAT). 
Q64586      CYTOCHROME P450 (STEROID 11-BETA-HYDROXYLASE) (EC 1.14.14.1) - RATTUS NORVEGICUS (RAT). 
YU34_MYCTU  PUTATIVE CYTOCHROME P450 CY339.34C (EC 1.14.-.-) - MYCOBACTERIUM TUBERCULOSIS. 
 
AVNA_ASPPA  AVERANTIN OXIDOREDUCTASE (EC 1.14.-.-) (CYTOCHROME P450 60A1) - ASPERGILLUS PARASITICUS. 
CP09_MYCTU  CYTOCHROME P450 51-LIKE RV3059 (EC 1.14.-.-) - MYCOBACTERIUM TUBERCULOSIS. 
CP10_LYMST  CYTOCHROME P450 10 (EC 1.14.-.-) (CYPX) - LYMNAEA STAGNALIS (GREAT POND SNAIL). 
CP2B_HUMAN  25-HYDROXYVITAMIN D-1 ALPHA HYDROXYLASE, MITOCHONDRIAL PRECURSOR (EC 1.14.-.-) (25-OHD-1 ALPHA-HYDROXYLASE) (25-HYDROXYVITAMIN D3 1- ALPHA-HYDROXYLASE) (VD3 1A HYDROXYLASE) (P450C1 ALPHA) (P450VD1- ALPHA) - HOMO SAPIENS (HUMAN). 
CP2B_MOUSE  25-HYDROXYVITAMIN D-1 ALPHA HYDROXYLASE, MITOCHONDRIAL PRECURSOR (EC 1.14.-.-) (25-OHD-1 ALPHA-HYDROXYLASE) (25-HYDROXYVITAMIN D3 1- ALPHA-HYDROXYLASE) (VD3 1A HYDROXYLASE) (P450C1 ALPHA) (P450VD1- ALPHA) - MUS MUSCULUS (MOUSE). 
CP2B_RAT    25-HYDROXYVITAMIN D-1 ALPHA HYDROXYLASE, MITOCHONDRIAL PRECURSOR (EC 1.14.-.-) (25-OHD-1 ALPHA-HYDROXYLASE) (25-HYDROXYVITAMIN D3 1- ALPHA-HYDROXYLASE) (VD3 1A HYDROXYLASE) (P450C1 ALPHA) (P450VD1- ALPHA) - RATTUS NORVEGICUS (RAT). 
CP36_RABIT  Cytochrome P450 3A6 (EC 1.14.14.1) (CYPIIIA6) (P450-3C) - Oryctolagus cuniculus (Rabbit). 
CP3T_PIG    Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29) - Sus scrofa (Pig). 
CPCB_RAT    CYTOCHROME P450 2C11 (EC 1.14.14.1) (CYPIIC11) (P-450(M-1)) (P450H) (P450-UT-A) (UT-2) - RATTUS NORVEGICUS (RAT). 
CPCM_RAT    CYTOCHROME P450 2C22 (EC 1.14.14.1) (CYPIIC22) (P450 MD) (P450 P49) - RATTUS NORVEGICUS (RAT). 
CPCT_MOUSE  CYTOCHROME P450 2C29 (EC 1.14.14.1) (CYPIIC29) (P-450 MUT-2) (ALDEHYDE OXYGENASE) - MUS MUSCULUS (MOUSE). 
CPCU_RABIT  CYTOCHROME P450 2C30 (EC 1.14.14.1) (CYPIIC30) - ORYCTOLAGUS CUNICULUS (RABBIT). 
CPM1_HUMAN  CYTOCHROME P450 11A1, MITOCHONDRIAL PRECURSOR (EC 1.14.15.6) (CYPXIA1) (P450(SCC)) (CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME) (CHOLESTEROL DESMOLASE) - HOMO SAPIENS (HUMAN). 
CPM1_RAT    CYTOCHROME P450 11A1, MITOCHONDRIAL PRECURSOR (EC 1.14.15.6) (CYPXIA1) (P450(SCC)) (CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME) (CHOLESTEROL DESMOLASE) - RATTUS NORVEGICUS (RAT). 
CPN1_HUMAN  CYTOCHROME P450 11B1 PRECURSOR (EC 1.14.15.4) (CYPXIB1) (P450C11) (STEROID 11-BETA-HYDROXYLASE) - HOMO SAPIENS (HUMAN). 
CPN1_PAPHA  CYTOCHROME P450 11B1 PRECURSOR (EC 1.14.15.4) (CYPXIB1) (P450C11) (STEROID 11-BETA-HYDROXYLASE) - PAPIO HAMADRYAS (HAMADRYAS BABOON). 
CPN1_RAT    CYTOCHROME P450 11B1 PRECURSOR (EC 1.14.15.4) (CYPXIB1) (P450C11) (STEROID 11-BETA-HYDROXYLASE) (P450(11 BETA)-DS) - RATTUS NORVEGICUS (RAT). 
CPN2_HUMAN  CYTOCHROME P450 11B2 PRECURSOR (EC 1.14.15.4) (CYPXIB2) (P-450ALDO) (ALDOSTERONE SYNTHASE) (ALDOS) (ALDOSTERONE-SYNTHESIZING ENZYME) (STEROID 18-HYDROXYLASE) (P-450C18) - HOMO SAPIENS (HUMAN). 
CPN2_MESAU  CYTOCHROME P450 11B2 PRECURSOR (EC 1.14.15.4) (C450XIB2) (ALDOSTERONE SYNTHASE) (P-450ALDO) (ALDOS) (ALDOSTERONE-SYNTHESIZING ENZYME) (STEROID 18-HYDROXYLASE) (P-450C18) - MESOCRICETUS AURATUS (GOLDEN HAMSTER). 
CPN2_RAT    CYTOCHROME P450 11B2 PRECURSOR (EC 1.14.15.4) (CYPXIB2) (P450-ALDO-1) (ALDOSTERONE SYNTHASE) - RATTUS NORVEGICUS (RAT). 
CPN3_RAT    CYTOCHROME P450 11B3 PRECURSOR (EC 1.14.15.4) (CYPXIB3) (P450-ALDO-2) (ALDOSTERONE SYNTHASE) - RATTUS NORVEGICUS (RAT). 
CPT7_CHICK  CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - GALLUS GALLUS (CHICKEN). 
CPT7_ONCMY  CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - ONCORHYNCHUS MYKISS (RAINBOW TROUT) (SALMO GAIRDNERI). 
CPT7_ORYLA  CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - ORYZIAS LATIPES (MEDAKA FISH). 
CPT7_SQUAC  CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - SQUALUS ACANTHIAS (SPINY DOGFISH). 
CPXU_RHISN  CYTOCHROME P450 BJ-4 HOMOLOG (EC 1.14.14.-) - RHIZOBIUM SP. (STRAIN NGR234). 
O08447      PUTATIVE CYTOCHROME P450 MONOXYGENASE (EC 1.14.14.1) - MYCOBACTERIUM TUBERCULOSIS. 
O13254      CYTOCHROME P450 SCC (EC 1.14.14.1) - GALLUS GALLUS (CHICKEN). 
O13820      PUTATIVE CYTOCHROME P450 C19A8.04 IN CHROMOSOME I (EC 1.14.-.-) - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST). 
O16156      CYTOCHROME P450 30 - MERCENARIA MERCENARIA (NORTHERN QUAHOG). 
O16482      SIMILAR TO CYTOCHROME P450 - CAENORHABDITIS ELEGANS. 
O16670      F41B5.4 PROTEIN - CAENORHABDITIS ELEGANS.     
O16672      F41B5.7 PROTEIN - CAENORHABDITIS ELEGANS.     
O17655      C41G6.1 PROTEIN - CAENORHABDITIS ELEGANS.     
O33934      ERYCII - SACCHAROPOLYSPORA ERYTHRAEA (STREPTOMYCES ERYTHRAEUS). 
O44655      B0213.10 PROTEIN - CAENORHABDITIS ELEGANS.    
O44658      B0213.14 PROTEIN - CAENORHABDITIS ELEGANS.    
O45317      Y17D7A.4 PROTEIN - CAENORHABDITIS ELEGANS.    
O45659      K05D4.4 PROTEIN - CAENORHABDITIS ELEGANS.     
O46515      CYTOCHROME P450 CHOLESTEROL SIDE-CHAIN CLEAVAGE - EQUUS CABALLUS (HORSE). 
O54225      DTDP-4-KETO-6-DEOXY-HEXOSE 3,4-ISOMERASE - SACCHAROPOLYSPORA ERYTHRAEA (STREPTOMYCES ERYTHRAEUS). 
O65624      CYTOCHROME P450 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS). 
O69653      PUTATIVE CYTOCHROME P-450 - MYCOBACTERIUM TUBERCULOSIS. 
O81077      PUTATIVE CYTOCHROME P450 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS). 
O86330      HYPOTHETICAL 47.9 KD PROTEIN - MYCOBACTERIUM TUBERCULOSIS. 
O87829      CYTOCHROME P450 MONOOXYGENASE - STREPTOMYCES ANTIBIOTICUS. 
P95099      HYPOTHETICAL 56.2 KD PROTEIN (EC 1.14.14.1) - MYCOBACTERIUM TUBERCULOSIS. 
Q27465      SIMILAR TO CYTOCHROME P450 (EC 1.14.14.1) - CAENORHABDITIS ELEGANS. 
Q27470      SIMILAR TO CYTOCHROME P450 (EC 1.14.14.1) - CAENORHABDITIS ELEGANS. 
Q27482      SIMILAR TO CYTOCHROME P450 (EC 1.14.14.1) - CAENORHABDITIS ELEGANS. 
THAS_PIG    THROMBOXANE-A SYNTHASE (EC 5.3.99.5) (TXA SYNTHASE) (TXS) - SUS SCROFA (PIG). 
THAS_RAT    THROMBOXANE-A SYNTHASE (EC 5.3.99.5) (TXA SYNTHASE) (TXS) - RATTUS NORVEGICUS (RAT). 
 
C2F1_HUMAN  CYTOCHROME P450 2F1 (EC 1.14.14.1) (CYPIIF1) - HOMO SAPIENS (HUMAN). 
C2F2_MOUSE  CYTOCHROME P450 2F2 (EC 1.14.14.-) (CYPIIF2) (NAPHTHALENE DEHYDROGENASE) (NAPHTHALENE HYDROXYLASE) (P450-NAH-2) - MUS MUSCULUS (MOUSE). 
C4D1_DROME  CYTOCHROME P450 4D1 (EC 1.14.14.1) (CYPIVD1) - DROSOPHILA MELANOGASTER (FRUIT FLY). 
C4D1_DROSI  CYTOCHROME P450 4D1 (EC 1.14.14.1) (CYPIVD1) - DROSOPHILA SIMULANS (FRUIT FLY). 
C4D2_DROME  CYTOCHROME P450 4D2 (EC 1.14.14.1) (CYPIVD2) - DROSOPHILA MELANOGASTER (FRUIT FLY). 
C718_MENPI  CYTOCHROME P450 71A8 (EC 1.14.-.-) - MENTHA PIPERITA (PEPPERMINT). 
C755_EUSGR  FLAVONOID 3',5'-HYDROXYLASE (EC 1.14.-.-) (F3'5'H) (CYTOCHROME P450 75A5) - EUSTOMA GRANDIFLORUM (BLUEBELLS) (LISIANTHUS RUSSELLIANUS). 
C756_CAMME  FLAVONOID 3',5'-HYDROXYLASE (EC 1.14.-.-) (F3'5'H) (CYTOCHROME P450 75A6) - CAMPANULA MEDIUM (CANTERBURY BELLS). 
C757_EUSGR  FLAVONOID 3',5'-HYDROXYLASE (EC 1.14.-.-) (F3'5'H) (CYTOCHROME P450 75A7) - EUSTOMA GRANDIFLORUM (BLUEBELLS) (LISIANTHUS RUSSELLIANUS). 
C772_SOLME  CYTOCHROME P450 77A2 (EC 1.14.-.-) (CYPLXXVIIA2) (P-450EG5) - SOLANUM MELONGENA (EGGPLANT) (AUBERGINE). 
C7E1_SORBI  CYTOCHROME P450 71E1 (EC 1.14.-.-) - SORGHUM BICOLOR MILO (SORGHUM). 
C823_SOYBN  CYTOCHROME P450 82A3 (EC 1.14.-.-) (P450 CP6) - GLYCINE MAX (SOYBEAN). 
C824_SOYBN  CYTOCHROME P450 82A4 (EC 1.14.-.-) (P450 CP9) - GLYCINE MAX (SOYBEAN). 
C861_ARATH  CYTOCHROME P450 86A1 (EC 1.14.-.-) (CYPLXXXVI) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS). 
C892_ARATH  CYTOCHROME P450 89A2 (EC 1.14.-.-) (CYPLXXXIX) (ATH 6-1) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS). 
C931_SOYBN  CYTOCHROME P450 93A1 (EC 1.14.-.-) - GLYCINE MAX (SOYBEAN). 
C932_SOYBN  CYTOCHROME P450 93A2 (EC 1.14.-.-) - GLYCINE MAX (SOYBEAN). 
C933_SOYBN  CYTOCHROME P450 93A3 (EC 1.14.-.-) (P450 CP5) - GLYCINE MAX (SOYBEAN). 
CP18_DROME  CYTOCHROME P450 18 (EC 1.14.14.-) (CYPXVIII) - DROSOPHILA MELANOGASTER (FRUIT FLY). 
CP27_HUMAN  STEROL 26-HYDROXYLASE, MITOCHONDRIAL PRECURSOR (EC 1.14.-.-) (VITAMIN D(3) 25-HYDROXYLASE) (5-BETA-CHOLESTANE-3-ALPHA,7-ALPHA,12-ALPHA-TRIOL 27-HYDROXYLASE) - HOMO SAPIENS (HUMAN). 
CP27_RABIT  STEROL 26-HYDROXYLASE, MITOCHONDRIAL PRECURSOR (EC 1.14.-.-) (VITAMIN D(3) 25-HYDROXYLASE) (5-BETA-CHOLESTANE-3-ALPHA,7-ALPHA,12-ALPHA-TRIOL 27-HYDROXYLASE) - ORYCTOLAGUS CUNICULUS (RABBIT). 
CP27_RAT    STEROL 26-HYDROXYLASE, MITOCHONDRIAL PRECURSOR (EC 1.14.-.-) (VITAMIN D(3) 25-HYDROXYLASE) (5-BETA-CHOLESTANE-3-ALPHA,7-ALPHA,12-ALPHA-TRIOL 27-HYDROXYLASE) - RATTUS NORVEGICUS (RAT). 
CP31_RAT    Cytochrome P450 3A1 (EC 1.14.14.1) (CYPIIIA1) (P450-PCN1) - Rattus norvegicus (Rat). 
CP33_HUMAN  Cytochrome P450 3A3 (EC 1.14.14.1) (CYPIIIA3) (HLp) - Homo sapiens (Human). 
CP34_HUMAN  Cytochrome P450 3A4 (EC 1.14.14.1) (CYPIIIA4) (Nifedipine oxidase) (NF-25) (P450-PCN1) - Homo sapiens (Human). 
CP39_RAT    Cytochrome P450 3A9 (EC 1.14.14.1) (CYPIIIA9) (P450-OLF3) (Olfactive) (3AH15) - Rattus norvegicus (Rat). 
CP3A_MESAU  Cytochrome P450 3A10 (EC 1.14.14.1) (CYPIIIA10) (6 beta-hydroxylase) - Mesocricetus auratus (Golden hamster). 
CP3C_CANFA  Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12) (P450-PBD-1) - Canis familiaris (Dog). 
CP3D_MOUSE  Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13) - Mus musculus (Mouse). 
CP3E_CAVPO  Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14) - Cavia porcellus (Guinea pig). 
CP3O_SHEEP  Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24) - Ovis aries (Sheep). 
CP3R_ONCMY  Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27) - Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri). 
CP51_CANAL  CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450-L1A1) (STEROL 14- ALPHA DEMETHYLASE) (LANOSTEROL 14-ALPHA DEMETHYLASE) (P450-14DM) - CANDIDA ALBICANS (YEAST). 
CP51_CANGA  CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450-L1A1) (STEROL 14- ALPHA-DEMETHYLASE) (LANOSTEROL 14-ALPHA DEMETHYLASE) (P450-14DM) - CANDIDA GLABRATA (YEAST) (TORULOPSIS GLABRATA). 
CP51_PENIT  CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450-L1A1) (STEROL 14- ALPHA DEMETHYLASE) (EBURICOL 14-ALPHA-DEMETHYLASE) (P450-14DM) - PENICILLIUM ITALICUM. 
CP51_SCHPO  PROBABLE CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450-L1A1) (STEROL 14-ALPHA DEMETHYLASE) (LANOSTEROL 14-ALPHA DEMETHYLASE) (P450-14DM) - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST). 
CP51_UNCNE  CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450-L1A1) (STEROL 14- ALPHA DEMETHYLASE) (EBURICOL 14-ALPHA-DEMETHYLASE) (P450-14DM) - UNCINULA NECATOR (GRAPE POWDERY MILDEW). 
CP51_USTMA  CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450-L1A1) (STEROL 14- ALPHA DEMETHYLASE) (LANOSTEROL 14-ALPHA DEMETHYLASE) (P450-14DM) - USTILAGO MAYDIS (SMUT FUNGUS). 
CP74_ARATH  ALLENE OXIDE SYNTHASE PRECURSOR (EC 4.2.1.92) (HYDROPEROXIDE DEHYDRASE) (CYTOCHROME P450 74A) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS). 
CP74_LINUS  ALLENE OXIDE SYNTHASE PRECURSOR (EC 4.2.1.92) (HYDROPEROXIDE DEHYDRASE) (CYTOCHROME P450 74A) - LINUM USITATISSIMUM (FLAX) (LINSEED). 
CPA3_RAT    Cytochrome P450 2A3 (EC 1.14.14.1) (CYPIIA3) (Coumarin 7-hydroxylase) - Rattus norvegicus (Rat). 
CPA4_MOUSE  Cytochrome P450 2A4 (EC 1.14.14.1) (CYPIIA4) (Testosterone 15-alpha- hydroxylase) (P450-15-alpha) (P450-IIA3.1) - Mus musculus (Mouse). 
CPA5_MOUSE  Cytochrome P450 2A5 (EC 1.14.14.1) (CYPIIA5) (Coumarin 7-hydroxylase) (P450-15-COH) (P450-IIA3.2) - Mus musculus (Mouse). 
CPA6_HUMAN  Cytochrome P450 2A6 (EC 1.14.14.1) (CYPIIA6) (Coumarin 7-hydroxylase) (IIA3) (CYP2A3) (P450(I)) - Homo sapiens (Human). 
CPA7_HUMAN  Cytochrome P450 2A7 (EC 1.14.14.1) (CYPIIA7) (P450-IIA4) - Homo sapiens (Human). 
CPAB_RABIT  Cytochrome P450 2A11 (EC 1.14.14.1) (CYPIIA11) (P450-IIA11) - Oryctolagus cuniculus (Rabbit). 
CPB9_MOUSE  Cytochrome P450 2B9 (EC 1.14.14.1) (CYPIIB9) (Testosterone 16-alpha hydroxylase) (P450-16-alpha) (Clone PF26) - Mus musculus (Mouse). 
CPBA_MOUSE  Cytochrome P450 2B10 (EC 1.14.14.1) (CYPIIB10) (Testosterone 16-alpha hydroxylase) (P450-16-alpha) (Clone PF3/46) - Mus musculus (Mouse). 
CPBB_CANFA  Cytochrome P450 2B11 (EC 1.14.14.1) (CYPIIB11) (P450 PBD-2) - Canis familiaris (Dog). 
CPC2_RABIT  CYTOCHROME P450 2C2 (EC 1.14.14.1) (CYPIIC2) (P450 PBC2) (PHP2) (LAURATE OMEGA-1 HYDROXYLASE) - ORYCTOLAGUS CUNICULUS (RABBIT). 
CPC3_RABIT  CYTOCHROME P450 2C3 (EC 1.14.14.1) (CYPIIC3) (P450 PBC3) (P450 FORM 3B) - ORYCTOLAGUS CUNICULUS (RABBIT). 
CPC4_RABIT  CYTOCHROME P450 2C4 (EC 1.14.14.1) (CYPIIC4) (PROGESTERONE 21- HYDROXYLASE) (P450 PBC4) (P1-88) - ORYCTOLAGUS CUNICULUS (RABBIT). 
CPC5_RABIT  CYTOCHROME P450 2C5 (EC 1.14.14.1) (CYPIIC5) (P450 1) (PROGESTERONE 21-HYDROXYLASE) (P450IIC5) - ORYCTOLAGUS CUNICULUS (RABBIT). 
CPC6_RAT    CYTOCHROME P450 2C6 (EC 1.14.14.1) (CYPIIC6) (P450 PB1) (PTF2) - RATTUS NORVEGICUS (RAT). 
CPC8_HUMAN  CYTOCHROME P450 2C8 (EC 1.14.14.1) (CYPIIC8) (P450 FORM 1) (P450 MP- 12/MP-20) (P450 IIC2) (S-MEPHENYTOIN 4-HYDROXYLASE) - HOMO SAPIENS (HUMAN). 
CPCD_RAT    CYTOCHROME P450 2C13, MALE-SPECIFIC (EC 1.14.14.1) (CYPIIC13) (P450- G) (UT-5) - RATTUS NORVEGICUS (RAT). 
CPCG_RABIT  CYTOCHROME P450 2C16 (EC 1.14.14.1) (CYPIIC16) - ORYCTOLAGUS CUNICULUS (RABBIT). 
CPCN_RAT    CYTOCHROME P450 2C23 (EC 1.14.14.1) (CYPIIC23) (ARACHIDONIC ACID EPOXYGENASE) - RATTUS NORVEGICUS (RAT). 
CPCP_MESAU  CYTOCHROME P450 2C26 (EC 1.14.14.1) (CYPIIC26) (P450 HSM2) - MESOCRICETUS AURATUS (GOLDEN HAMSTER). 
CPCQ_MESAU  CYTOCHROME P450 2C27 (EC 1.14.14.1) (CYPIIC27) (P450 HSM3) - MESOCRICETUS AURATUS (GOLDEN HAMSTER). 
CPD1_RAT    Cytochrome P450 2D1 (EC 1.14.14.1) (CYPIID1) (P450-DB1) (P450-CMF1A) (P450-UT-7) (Debrisoquine 4-hydroxylase) - Rattus norvegicus (Rat). 
CPD3_RAT    Cytochrome P450 2D3 (EC 1.14.14.1) (CYPIID3) (P450-DB3) (Debrisoquine 4-hydroxylase) - Rattus norvegicus (Rat). 
CPD4_RAT    Cytochrome P450 2D4 (EC 1.14.14.1) (CYPIID4) (P450-DB4) (P450-CMF3) (Debrisoquine 4-hydroxylase) - Rattus norvegicus (Rat). 
CPD5_RAT    Cytochrome P450 2D5 (EC 1.14.14.1) (CYPIID5) (P450-DB5) (P450-CMF1B) (Debrisoquine 4-hydroxylase) - Rattus norvegicus (Rat). 
CPD6_HUMAN  Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6) (P450-DB1) (Debrisoquine 4-hydroxylase) - Homo sapiens (Human). 
CPD9_MOUSE  Cytochrome P450 2D9 (EC 1.14.14.1) (CYPIID9) (P450-16-alpha) (CA) (Testosterone 16-alpha hydroxylase) - Mus musculus (Mouse). 
CPDA_MOUSE  Cytochrome P450 2D10 (EC 1.14.14.1) (CYPIID10) (P450-16-alpha) (P450CB) (Testosterone 16-alpha hydroxylase) - Mus musculus (Mouse). 
CPDF_CANFA  Cytochrome P450 2D15 (EC 1.14.14.1) (CYPIID15) (P450 DUT2) - Canis familiaris (Dog). 
CPDG_CAVPO  Cytochrome P450 2D16 (EC 1.14.14.1) (CYPIID16) - Cavia porcellus (Guinea pig). 
CPDH_MACFA  Cytochrome P450 2D17 (EC 1.14.14.1) (CYPIID17) - Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey). 
CPDI_RAT    Cytochrome P450 2D18 (EC 1.14.14.1) (CYPIID18) (P450 2D-29/2D-35) - Rattus norvegicus (Rat). 
CPDJ_CALJA  Cytochrome P450 2D19 (EC 1.14.14.1) (CYPIID19) (P450 CM2D-1) - Callithrix jacchus (Common marmoset). 
CPE1_BOVIN  Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) - Bos taurus (Bovine). 
CPE1_HUMAN  Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (P450-J) - Homo sapiens (Human). 
CPE1_MESAU  Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (P450-J) - Mesocricetus auratus (Golden hamster). 
CPE1_MOUSE  Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (P450-J) (P450-ALC) - Mus musculus (Mouse). 
CPE1_PIG    Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (P450-J) (P-450-J) - Sus scrofa (Pig). 
CPE1_RABIT  Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (Isozyme 3A) (P450-ALC) - Oryctolagus cuniculus (Rabbit). 
CPE1_RAT    Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (P450-J) (P450RLM6) - Rattus norvegicus (Rat). 
CPJ1_RABIT  Cytochrome P450 2J1 (EC 1.14.14.1) (CYPIIJ1) (P-450IB) - Oryctolagus cuniculus (Rabbit). 
CPJ2_HUMAN  Cytochrome P450 2J2 (EC 1.14.14.1) (CYPIIJ2) (Arachidonic acid epoxygenase) - Homo sapiens (Human). 
CPK1_ONCMY  CYTOCHROME P450 2K1 (EC 1.14.14.1) (CYPIIK1) (P450 LMC2) - ONCORHYNCHUS MYKISS (RAINBOW TROUT) (SALMO GAIRDNERI). 
CPM1_BOVIN  CYTOCHROME P450 11A1, MITOCHONDRIAL PRECURSOR (EC 1.14.15.6) (CYPXIA1) (P450(SCC)) (CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME) (CHOLESTEROL DESMOLASE) - BOS TAURUS (BOVINE). 
CPM1_CAPHI  CYTOCHROME P450 11A1, MITOCHONDRIAL PRECURSOR (EC 1.14.15.6) (CYPXIA1) (P450(SCC)) (CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME) (CHOLESTEROL DESMOLASE) - CAPRA HIRCUS (GOAT). 
CPM1_ONCMY  CYTOCHROME P450 11A1, MITOCHONDRIAL PRECURSOR (EC 1.14.15.6) (CYPXIA1) (P450(SCC)) (CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME) (CHOLESTEROL DESMOLASE) - ONCORHYNCHUS MYKISS (RAINBOW TROUT) (SALMO GAIRDNERI). 
CPM1_PIG    CYTOCHROME P450 11A1, MITOCHONDRIAL PRECURSOR (EC 1.14.15.6) (CYPXIA1) (P450(SCC)) (CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME) (CHOLESTEROL DESMOLASE) - SUS SCROFA (PIG). 
CPM1_SHEEP  CYTOCHROME P450 11A1, MITOCHONDRIAL PRECURSOR (EC 1.14.15.6) (CYPXIA1) (P450(SCC)) (CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME) (CHOLESTEROL DESMOLASE) - OVIS ARIES (SHEEP). 
CPN1_CAVPO  CYTOCHROME P450 11B1 PRECURSOR (EC 1.14.15.4) (CYPXIB1) (P450C11) (STEROID 11-BETA-HYDROXYLASE) (ALDOSTERONE SYNTHASE) - CAVIA PORCELLUS (GUINEA PIG). 
CPN1_MESAU  CYTOCHROME P450 11B1 PRECURSOR (EC 1.14.15.4) (CYPXIB1) (P450C11) (STEROID 11-BETA-HYDROXYLASE) - MESOCRICETUS AURATUS (GOLDEN HAMSTER). 
CPP1_DROAC  CYTOCHROME P450 12B1 PRECURSOR (EC 1.14.-.-) (CYPXIIB1) - DROSOPHILA ACANTHOPTERA (FRUIT FLY). 
CPS1_BOVIN  CYTOCHROME P450 XXIA1 (EC 1.14.99.10) (STEROID 21-HYDROXYLASE) (P450-C21) - BOS TAURUS (BOVINE). 
CPS1_HUMAN  CYTOCHROME P450 XXIB (EC 1.14.99.10) (STEROID 21-HYDROXYLASE) (P450-C21B) - HOMO SAPIENS (HUMAN). 
CPS1_PIG    CYTOCHROME P450 XXIA1 (EC 1.14.99.10) (STEROID 21-HYDROXYLASE) (P450-C21) - SUS SCROFA (PIG). 
CPS3_PIG    CYTOCHROME P450 XXIA3 (EC 1.14.99.10) (STEROID 21-HYDROXYLASE) (P450-C21) - SUS SCROFA (PIG). 
CPT7_ICTPU  CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - ICTALURUS PUNCTATUS (CHANNEL CATFISH). 
CPT7_RANDY  CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - RANA DYBOWSKII (FROG). 
CPXN_ANASP  PROBABLE CYTOCHROME P450 110 (EC 1.14.-.-) (ORF3) - ANABAENA SP. (STRAIN PCC 7120). 
CPXU_BRAJA  CYTOCHROME P450 BJ-4 (EC 1.14.14.-) (CYTOCHROME P450 117) - BRADYRHIZOBIUM JAPONICUM. 
CPZ6_CANFA  CYTOCHROME P450 2C41 (EC 1.14.14.1) (CYPIIC41) - CANIS FAMILIARIS (DOG). 
ERG5_YEAST  CYTOCHROME P450 61 (EC 1.14.14.-) (C-22 STEROL DESATURASE) - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST). 
HNF4_DROME  TRANSCRIPTION FACTOR HNF-4 HOMOLOG (DHNF4) - DROSOPHILA MELANOGASTER (FRUIT FLY). 
O02641      PUTATIVE CYTOCHROME P450 (EC 1.14.14.1) - CAENORHABDITIS ELEGANS. 
O16362      F44C8.1 PROTEIN - CAENORHABDITIS ELEGANS.     
O16671      F41B5.3 PROTEIN - CAENORHABDITIS ELEGANS.     
O16673      F41B5.2 PROTEIN - CAENORHABDITIS ELEGANS.     
O22185      PUTATIVE CYTOCHROME P450 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS). 
O22188      PUTATIVE CYTOCHROME P450 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS). 
O22744      PUTATIVE OBTUSIFOLIOL 14-ALPHA DEMETHYLASE - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS). 
O23154      CYTOCHROME P450-LIKE PROTEIN - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS). 
O23387      SIMILARITY TO CYTOCHROME P450 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS). 
O23389      SIMILARITY TO CYTOCHROME P450 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS). 
O23397      ALLENE OXIDE SYNTHASE - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS). 
O26651      DNA HELICASE II RELATED PROTEIN - METHANOBACTERIUM THERMOAUTOTROPHICUM. 
O33959      TYL ORFX - STREPTOMYCES FRADIAE.              
O44652      K07C6.2 PROTEIN - CAENORHABDITIS ELEGANS.     
O44656      B0213.11 PROTEIN - CAENORHABDITIS ELEGANS.    
O44657      B0213.12 PROTEIN - CAENORHABDITIS ELEGANS.    
O44659      B0213.15 PROTEIN - CAENORHABDITIS ELEGANS.    
O44704      C45H4.2 PROTEIN - CAENORHABDITIS ELEGANS.     
O45605      H02I12.8 PROTEIN - CAENORHABDITIS ELEGANS.    
O46051      EG:152A3.2 PROTEIN - DROSOPHILA MELANOGASTER (FRUIT FLY). 
O46053      COSMID 152A3 - DROSOPHILA MELANOGASTER (FRUIT FLY). 
O48786      PUTATIVE CYTOCHROME P450 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS). 
O52819      PCZA363.3 - AMYCOLATOPSIS ORIENTALIS.         
O58111      230AA LONG HYPOTHETICAL COBALAMIN SYNTHASE - PYROCOCCUS HORIKOSHII. 
O61204      B0213.16 PROTEIN - CAENORHABDITIS ELEGANS.    
O61935      COSMID T09H2 - CAENORHABDITIS ELEGANS.        
O62377      T10H4.11 PROTEIN - CAENORHABDITIS ELEGANS.    
O62378      T10H4.10 PROTEIN - CAENORHABDITIS ELEGANS.    
O64853      PUTATIVE THROMBOXANE-A SYNTHASE - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS). 
O64989      STEROID 22-ALPHA-HYDROXYLASE - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS). 
O76345      CYTOCHROME P450 - HOMARUS AMERICANUS (AMERICAN LOBSTER). 
O76800      CYP6-LIKE MICROSOMAL CYTOCHROME P450 - DROSOPHILA MELANOGASTER (FRUIT FLY). 
O88037      HYPOTHETICAL 100.1 KD PROTEIN - STREPTOMYCES COELICOLOR. 
O93297      CYTOCHROME P450 2K4 (EC 1.14.14.1) (CYPIIK4) - ONCORHYNCHUS MYKISS (RAINBOW TROUT) (SALMO GAIRDNERI). 
O93304      CYTOCHROME P450 2K1 (EC 1.14.14.1) (CYPIIK1) (P450 LMC2) - ONCORHYNCHUS MYKISS (RAINBOW TROUT) (SALMO GAIRDNERI). 
P70983      ALKALINE AMYLOPULLULANASE - BACILLUS SP.      
P77900      HYPOTHETICAL 52.2 KD PROTEIN CY21B4.11C (EC 1.14.14.1) - MYCOBACTERIUM TUBERCULOSIS. 
P95746      HYPOTHETICAL 44.1 KD PROTEIN - STREPTOMYCES FRADIAE. 
P96813      HYPOTHETICAL 49.3 KD PROTEIN (EC 1.14.14.1) - MYCOBACTERIUM TUBERCULOSIS. 
Q06884      CYTOCHROME P450 IIIA (EC 1.14.14.1) (STEROID INDUCIBLE) - Rattus norvegicus (Rat). 
Q08078      CYTOCHROME P450 2C25 (EC 1.14.14.1) (CYPIIC25) (P450 HSM1) - MESOCRICETUS AURATUS (GOLDEN HAMSTER). 
Q16741      CYTOCHROME P450 (EC 1.14.99.10) (STEROID 21-HYDROXYLASE). (EC 1.14.14.1) - HOMO SAPIENS (HUMAN). 
Q16742      CYTOCHROME P450 (EC 1.14.99.10) (STEROID 21-HYDROXYLASE) - HOMO SAPIENS (HUMAN). 
Q16749      CYTOCHROME P450 (EC 1.14.99.10) (STEROID 21-HYDROXYLASE) - HOMO SAPIENS (HUMAN). 
Q16753      DEBRISOQUINE 4-HYDROXYLASE MUTANT ALLELE (EC 1.14.14.1) - Homo sapiens (Human). 
Q16874      CYTOCHROME P450 21-HYDROXYLASE (STEROID 21-MONOOXYGENASE) (EC 1.14.99.10) (STEROID 21-HYDROXYLASE) (CYTOCHROME P450 XXIA1) - HOMO SAPIENS (HUMAN). 
Q27471      SIMILAR TO CYTOCHROME P450 (EC 1.14.14.1) - CAENORHABDITIS ELEGANS. 
Q27506      K09A11.2 PROTEIN - CAENORHABDITIS ELEGANS.    
Q29454      CYTOCHROME P450 IID (EC 1.14.14.1) - Bos taurus (Bovine). 
Q29508      CYTOCHROME P450 (P450IIE2) (EC 1.14.14.1) - Oryctolagus cuniculus (Rabbit). 
Q42959      CYTOCHROME P450 (EC 1.14.14.1) - NICOTIANA TABACUM (COMMON TOBACCO). 
Q43071      CYTOCHROME P450 (EC 1.14.14.1) - PHALAENOPSIS SP. 
Q54296      POLYKETIDE SYNTHASE - STREPTOMYCES HYGROSCOPICUS. 
Q59163      CYTOCHROME P450 (EC 1.14.14.1) - ANABAENA VARIABILIS. 
Q64460      CYTOCHROME P450 (TESTOSTERONE 16-ALPHA HYDROXYLASE TYPE B) (EC 1.14.14.1) - Mus musculus (Mouse). 
Q64463      CYTOCHROME P450 (TESTOSTERONE 16-ALPHA HYDROXYLASE TYPE A) (EC 1.14.14.1) - Mus musculus (Mouse). 
Q64529      CYTOCHROME P450 16A-MS1 (EC 1.14.14.1) - Mus spretus (Western wild mouse). 
Q64530      CYTOCHROME P450 16A-MS2 (EC 1.14.14.1) - Mus spretus (Western wild mouse). 
Q64590      CYTOCHROME P450 (EC 1.14.14.1) - RATTUS NORVEGICUS (RAT). 
Q64615      CYTOCHROME P450 C27/25 (EC 1.14.14.1) - RATTUS NORVEGICUS (RAT). 
Q64639      CYTOCHROME P450 C27/25 (EC 1.14.14.1) - RATTUS NORVEGICUS (RAT). 
Q92088      CYTOCHROME P450 2M1 (EC 1.14.14.1) (CYPIIM1) (AURIC ACID OMEGA-6- HYDROXYLASE) (LMC1) - ONCORHYNCHUS MYKISS (RAINBOW TROUT) (SALMO GAIRDNERI). 
Q92129      CYTOCHROME P-450 (EC 1.14.14.1) - Xenopus laevis (African clawed frog). 
STCF_EMENI  PROBABLE STERIGMATOCYSTIN BIOSYNTHESIS P450 MONOOXYGENASE STCF (EC 1.14.-.-) (CYTOCHROME P450 60A2) - EMERICELLA NIDULANS (ASPERGILLUS NIDULANS). 
STCL_EMENI  PROBABLE STERIGMATOCYSTIN BIOSYNTHESIS P450 MONOOXYGENASE STCL (EC 1.14.-.-) (CYTOCHROME P450 60B) - EMERICELLA NIDULANS (ASPERGILLUS NIDULANS). 
THAS_HUMAN  THROMBOXANE-A SYNTHASE (EC 5.3.99.5) (TXA SYNTHASE) (TXS) - HOMO SAPIENS (HUMAN). 
THAS_MOUSE  THROMBOXANE-A SYNTHASE (EC 5.3.99.5) (TXA SYNTHASE) (TXS) (TS) - MUS MUSCULUS (MOUSE). 
TR11_FUSSP  ISOTRICHODERMIN C-15 HYDROXYLASE (EC 1.14.-.-) (CYTOCHROME P450 65A1) - FUSARIUM SPOROTRICHIOIDES. 
YDAK_CAEEL  PUTATIVE CYTOCHROME P450 C34B7.3 IN CHROMOSOME I (EC 1.14.-.-) - CAENORHABDITIS ELEGANS.

Scan History

OWL25_3    2  1000 NSINGLE    
SPTR37_9f  3  300  NSINGLE

Initial Motifs

Motif 1  width=12
Element                        Seqn Id          St    Int   Rpt 
EDEPIHTERRRL                   RSU171302       110    110     - 
HEGREHARLRAI                   BJU126781        88     88     - 
KDPPTHTRLRRL                   BJU126782        50     50     - 
SNGETHGKRRSG                   CPXC_AGRT6      106    106     - 
SDPPTHTRLRKL                   CPXJ_SACER       93     93     - 
TDPPDHTRLRKL                   CPXK_SACER       96     96     - 
LDPPEHGTRRRM                   CPXE_STRGO       97     97     - 
MDDPEHARLRRM                   CPXF_STRGO       97     97     - 
MDPPKHTKLRAL                   CPXM_BACSU       86     86     - 
VDDPEHNTQRRM                   CPXH_STRGR      105    105     - 
LDPPDHRKARSL                   CPXI_BACME       92     92     - 
MDPPTHTAYRGL                   CPXL_PSESP      105    105     - 
KDGTEHARERMA                   CPXD_AGRT6       96     96     - 
AATLEDERCRRL                   CPXG_STRSQ       75     75     - 
MDPPEHMHQRSM                   CP55_FUSOX       88     88     - 
LDPPDHTRLRHI                   S42052           93     93     - 
QDGPGHLRLRRL                   STMCARAA         97     97     - 
IDPPEHRALRKV                   B40634           90     90     - 
LDPPVHTQYRKV                   A48495           94     94     - 
MDPPEQRQFRAL                   CPXA_PSEPU      103    103     - 
 
Motif 2  width=17
Element                        Seqn Id          St    Int   Rpt 
DLHREFALALPMLVFAE              BJU126782       100     38     - 
DIVDRFAHPLPIKVICE              CPXJ_SACER      139     34     - 
NFTEMYASQLPALTIAS              CPXC_AGRT6      152     34     - 
DTVDLFAEICGPVAARI              CPXD_AGRT6      140     32     - 
DLVEHFALPVPSLVIAE              CPXG_STRSQ      122     35     - 
DLVKEFALPVPSYIIYT              CP55_FUSOX      138     38     - 
DLMDRYALPVSLLVLCE              S42052          140     35     - 
DVLEDFSYPLSIDVICE              STMCARAA        146     37     - 
DLVDVLAFPLPVTIVAE              B40634          134     32     - 
DLVPLLSAPLPLLTLAE              A48495          140     34     - 
DLIGDLLYEVPCIVALI              RSU171302       156     34     - 
DLRRHLSFPLPAMVISA              BJU126781       135     35     - 
DLIDEFAFPLPITVISE              CPXK_SACER      142     34     - 
DLVSQFALPVPSMVICR              CPXE_STRGO      144     35     - 
DLVTEFALPLPSLVICL              CPXF_STRGO      144     35     - 
NFTEDYAEPFPIRIFML              CPXA_PSEPU      149     34     - 
DIIEDFAGPLPVIIIAE              CPXM_BACSU      132     34     - 
ELVSAFALPVPSMVICA              CPXH_STRGR      152     35     - 
NIVDDLSSPFPSLVIAD              CPXI_BACME      138     34     - 
DFMTDCALYYPLHVVMT              CPXL_PSESP      152     35     - 
 
Motif 3  width=16
Element                        Seqn Id          St    Int   Rpt 
IVGIPEEAREQWHTWG               STMCARAA        163      0     - 
LLGVPYADRDELRDRT               S42052          157      0     - 
LLGVPFNDLEYLTQQN               CP55_FUSOX      155      0     - 
LLGVPPPDREHFQHDT               CPXG_STRSQ      139      0     - 
ILGICEASDVEIIRWS               CPXD_AGRT6      160      3     - 
VLGLPSEDTPFFTRLV               CPXC_AGRT6      169      0     - 
LAGLPEEDIPHLKYLT               CPXA_PSEPU      166      0     - 
LLGVDEKYRGEFGRWS               CPXJ_SACER      156      0     - 
MLGAPIEDRHLIKTYS               CPXM_BACSU      149      0     - 
LLGVPYADHAFFEERS               CPXH_STRGR      169      0     - 
LFGVPVKDRYQFKKWV               CPXI_BACME      155      0     - 
ALGVPEDDEPLMLKLT               CPXL_PSESP      169      0     - 
LLGLDPDCWYELYNWT               A48495          157      0     - 
FLGVPDEDIETCRQYG               RSU171302       173      0     - 
LMGVLYEDHAFFAGLS               BJU126781       152      0     - 
LFGMPQDDMFELAAGI               BJU126782       117      0     - 
LLGVPYEDHAFFQERS               CPXF_STRGO      161      0     - 
LLGVPYADHEFFQDAS               CPXE_STRGO      161      0     - 
LMGVEDSRRDDFRSWT               CPXK_SACER      159      0     - 
LLGLPPMDHEQFGDWS               B40634          151      0     - 
 
Motif 4  width=23
Element                        Seqn Id          St    Int   Rpt 
EYLARLARTKRERPDDAIISRLV        CPXF_STRGO      198     21     - 
DYLIPIIEQRRQKPGTDAISIVA        CPXA_PSEPU      202     20     - 
DYVRSVIADSGRRMRDDFLSRYL        CPXC_AGRT6      212     27     - 
CLFNDLVKKHRSAPNPSAFATML        CPXD_AGRT6      204     28     - 
GQLQRLVRLKRTEPGDDLLSGLI        CPXG_STRSQ      176     21     - 
DYLAILVEQRLVEPKDDIISKLC        CP55_FUSOX      192     21     - 
RYMATLVTRAQEQPGDDLLGILA        S42052          194     21     - 
DHLHLLIEQRRATPTGDLLTGLV        STMCARAA        198     19     - 
AYLKARCAERRADPGDDLISRLV        B40634          195     28     - 
GFCQELFESRRANPGPDIATLLA        A48495          199     26     - 
EFAGGLVDKLKADPNAKGWIPHA        RSU171302       216     27     - 
AYIRGKMRDKRQDPDDNLLTDLL        BJU126781       192     24     - 
AYFGDLIQRKRTDPRRDIVSMLV        BJU126782       160     27     - 
DYFNGFTVDRRSCPKDDVMSLLA        CPXL_PSESP      221     36     - 
QYLYPIVIEKRSNLSDDIISDLI        CPXI_BACME      198     27     - 
EYLGALIDRKRAEPGDGLLDELI        CPXH_STRGR      205     20     - 
DYFRDILSKRRAEPKEDLMTMLL        CPXM_BACSU      195     30     - 
NFILDLVERRRTEPGDDLLSALI        CPXJ_SACER      194     22     - 
EYLTELIAKKRTEPGDDLLTALL        CPXK_SACER      195     20     - 
GYLDGLITQFQTEPGAGLVGALV        CPXE_STRGO      197     20     - 
 
Motif 5  width=12
Element                        Seqn Id          St    Int   Rpt 
QAVDELMRWCTP                   STMCARAA        280     59     - 
SGIEELLRWLSV                   S42052          273     56     - 
QFVEELCRYHTA                   CP55_FUSOX      273     58     - 
SAVEELLRHLSV                   CPXG_STRSQ      254     55     - 
QAFEEGLRWVAP                   CPXD_AGRT6      281     54     - 
AAVEEGLRFEPP                   CPXC_AGRT6      293     58     - 
AACEELLRRFSL                   CPXA_PSEPU      283     58     - 
RLVDEAVRWTAP                   CPXL_PSESP      302     58     - 
AFVEEVLRCDAP                   BJU126782       242     59     - 
KAVQEILRMYPP                   BJU126781       272     57     - 
KAIEECLRYSGS                   RSU171302       299     60     - 
TATAEMVRHASP                   A48495          280     58     - 
AIVEEVLRYRPP                   B40634          276     58     - 
KAVEEMLRYRFH                   CPXI_BACME      280     59     - 
VVVEELLRFLSI                   CPXH_STRGR      286     58     - 
NVIEETLRYYSP                   CPXM_BACSU      276     58     - 
NAVEEILRYIAP                   CPXJ_SACER      276     59     - 
GAIEETLRYESP                   CPXK_SACER      276     58     - 
GAVEELLRYLAI                   CPXE_STRGO      278     58     - 
GAVEELLRYLTI                   CPXF_STRGO      275     54     - 
 
Motif 6  width=28
Element                        Seqn Id          St    Int   Rpt 
RTAMEDTEIGGQAIAKGDKVVLWYASGN   A48495          297      5     - 
RILTSDYEFHGVQLKKGDQILLPQMLSG   CPXA_PSEPU      299      4     - 
RLALKDIDLDGYVLPKGSLLALSVMSGL   CPXC_AGRT6      310      5     - 
RLVREDTEIRGFIVPKGDIVMTIQASAN   CPXD_AGRT6      298      5     - 
RAALQDADIEGTPVKAGEVVVVSLGAAN   CPXG_STRSQ      272      6     - 
RTAKEDVMIGDKLVRANEGIIASNQSAN   CP55_FUSOX      291      6     - 
RMAVTEVQIAGVTIPAGSFVIPSLLAAN   S42052          291      6     - 
RYATEDLDVGGVTVRKGEQVVAVIGAAG   STMCARAA        298      6     - 
RTTTKATEVAGVPIPADVMVNTWVLSAN   B40634          293      5     - 
RKAVVDTTVGEVDIPAGGRLLIVMASAN   RSU171302       316      5     - 
RYPRTDVTIAGEHIPAESKVLVGLPATS   BJU126781       292      8     - 
RIAQRDIELGGVVIPKNADVRVLIASGN   BJU126782       261      7     - 
RIATEDVLIGGRTIAAGEGVLCMISSAN   CPXF_STRGO      293      6     - 
RVATADIEVEGHLIRAGEGVIVVNSIAN   CPXE_STRGO      296      6     - 
RHTAEAVRFGDVVIPEGELVWVALGAAN   CPXK_SACER      294      6     - 
RFAAEEVEIGGVAIPQYSTVLVANGAAN   CPXJ_SACER      293      5     - 
RVATEDTELGGVFIKKGSSVISWIASAN   CPXM_BACSU      293      5     - 
RLATEDMEVDGATIRKGEGVVFSTSLIN   CPXH_STRGR      303      5     - 
RTVKQDNELLGVKLKKGDVVIAWMSACN   CPXI_BACME      297      5     - 
RTALADTEVRGQNIKRGDRIMLSYPSAN   CPXL_PSESP      319      5     - 
 
Motif 7  width=16
Element                        Seqn Id          St    Int   Rpt 
RDSDAHDDPDRFDPSA               B40634          321      0     - 
HDPDRFPDPERFDITR               STMCARAA        326      0     - 
RDSNLTDRPDDLDITR               S42052          319      0     - 
RDEEVFENPDEFNMNR               CP55_FUSOX      319      0     - 
RDPARFERPDAVDVTR               CPXG_STRSQ      300      0     - 
RDEDVFEDGESFNVFR               CPXD_AGRT6      326      0     - 
RDEKHYEHPQLFDVGR               CPXC_AGRT6      338      0     - 
LDERENACPMHVDFSR               CPXA_PSEPU      327      0     - 
RDPKQFPDPHRFDVTR               CPXJ_SACER      321      0     - 
RDGERFEDPDRFDITR               CPXK_SACER      322      0     - 
RDGTVYEDPDALDIHR               CPXE_STRGO      324      0     - 
RDAEVFPGGDDLDVAR               CPXF_STRGO      321      0     - 
RDADVFPRAETLDWDR               CPXH_STRGR      331      0     - 
RDEEVFSNPDEFDITR               CPXL_PSESP      347      0     - 
RDEDKFCKPDCFKIDR               CPXM_BACSU      321      0     - 
MDETMFENPFSVDIHR               CPXI_BACME      325      0     - 
RDPDAFADPDRFDPAR               BJU126782       289      0     - 
FDPHHFDDPEIFDIER               BJU126781       320      0     - 
RDDSMFPEPDDFDIHR               RSU171302       344      0     - 
RDESVFSDADRFDVTR               A48495          325      0     - 
 
Motif 8  width=10
Element                        Seqn Id          St    Int   Rpt 
LGFGAGVHRC                     CPXC_AGRT6      360      6     - 
LSFGHGIHFC                     BJU126782       320     15     - 
LAFSYGPHAC                     BJU126781       341      5     - 
LTFGIGSHTC                     RSU171302       366      6     - 
VGFGSGQHVC                     A48495          346      5     - 
SSFGHGVHFC                     B40634          345      8     - 
VGFGFGPHYC                     STMCARAA        351      9     - 
LAFGHGVHFC                     S42052          340      5     - 
LGFGFGDHRC                     CP55_FUSOX      342      7     - 
LAFGHGMHQC                     CPXG_STRSQ      321      5     - 
QSFGSGPHHC                     CPXD_AGRT6      347      5     - 
TTFGHGSHLC                     CPXA_PSEPU      348      5     - 
VAFGFGVHQC                     CPXF_STRGO      342      5     - 
LAFGFGVHQC                     CPXE_STRGO      345      5     - 
VAFGHGIHFC                     CPXK_SACER      343      5     - 
LSFGQGIHFC                     CPXJ_SACER      342      5     - 
LSFGFGIHFC                     CPXM_BACSU      342      5     - 
LAFGFGVHQC                     CPXH_STRGR      352      5     - 
LTFGNGPHFC                     CPXI_BACME      347      6     - 
LGFGWGAHMC                     CPXL_PSESP      368      5     - 
 
Motif 9  width=12
Element                        Seqn Id          St    Int   Rpt 
CLGRQLARIELR                   CPXG_STRSQ      330     -1     - 
CLGQHLARREII                   CPXA_PSEPU      357     -1     - 
CLGETLARIELQ                   CPXC_AGRT6      369     -1     - 
CPGAQISRQTVG                   CPXD_AGRT6      356     -1     - 
CLGAQLARVQLA                   BJU126782       329     -1     - 
CIGVALARLELK                   BJU126781       350     -1     - 
CLGATLARLEMK                   RSU171302       375     -1     - 
CVGSRLAEMQLR                   A48495          355     -1     - 
CLAAPLARLENR                   B40634          354     -1     - 
CLGAALAHQETA                   STMCARAA        360     -1     - 
CLGHSLARMTLR                   S42052          349     -1     - 
CIAEHLAKAELT                   CP55_FUSOX      351     -1     - 
CLGAPLARLEAN                   CPXM_BACSU      351     -1     - 
CLGQNLARAELD                   CPXH_STRGR      361     -1     - 
CLGAPLARLEMK                   CPXI_BACME      356     -1     - 
CLGQHLAKLEMK                   CPXL_PSESP      377     -1     - 
CMGRPLAKLEGE                   CPXJ_SACER      351     -1     - 
CVGAALARLEAQ                   CPXK_SACER      352     -1     - 
CLGQNLARLELE                   CPXE_STRGO      354     -1     - 
CLGQPLARVELQ                   CPXF_STRGO      351     -1     -

Final Motifs

Motif 1  width=12
Element                        Seqn Id          St    Int   Rpt 
MDPPEHSRLRRL                   Q59523           86     86     - 
MDPPEHTRMRKI                   O32460           98     98     - 
SDPPRHTRLRKL                   O87605           95     95     - 
MDDPEHARLRRM                   CPXF_STRGO       97     97     - 
LDPPEHGTRRRM                   CPXE_STRGO       97     97     - 
MDPPEHGTRRRM                   Q59831          102    102     - 
TDPPDHTRLRKL                   CPXK_SACER       96     96     - 
QDPPDHTRLRRL                   Q59819           96     96     - 
IDPPRHGPLRKL                   Q59910          101    101     - 
KDTPDHTRLRSL                   O31785           96     96     - 
SDPPTHTRLRKL                   CPXJ_SACER       93     93     - 
MDPPKHTKIRSV                   O34374           84     84     - 
VDDPEHRAQRRM                   O85697           99     99     - 
SDPPDHNRLRTL                   CPXY_BACSU       99     99     - 
MDPPKHTKLRAL                   CPXM_BACSU       86     86     - 
IDPPEHRALRKV                   CPXQ_SACER       76     76     - 
VDDPEHNTQRRM                   CPXH_STRGR      105    105     - 
KDPPTHTRLRRL                   CPXR_BRAJA       97     97     - 
YDPPEHTRLRQK                   O87674           91     91     - 
MDDPRHTRIRRL                   YP22_MYCTU       98     98     - 
MDPPEHTRYRKL                   O52544           92     92     - 
QNQPDHRRLRTL                   BIOI_BACSU       84     84     - 
SDPPDHRKRRSL                   CPXM_BACME       91     91     - 
LDPPDHTRLRHI                   FAS1_RHOFA       93     93     - 
MDPPEHTRLRRV                   Q54302           93     93     - 
YDPPEHTRLRQK                   O52823           99     99     - 
MDDPAHLLRRKL                   O53563           78     78     - 
KEPPTHTRLRRL                   CPXR_RHISN       97     97     - 
VEPPDHTRYRKT                   O08464          114    114     - 
MDDPAHLRMRTL                   P77902           89     89     - 
MDAPAHMNQRSM                   NOR2_CYLTO       95     95     - 
LDPPDHRKARSL                   CPXI_BACME       92     92     - 
MDPPASSRLRGL                   O87192           95     95     - 
SDGEEHARLRKL                   O52561          103    103     - 
LDDPRHQRLRSI                   YU44_MYCTU      113    113     - 
QDGPGHLRLRRL                   Q60005           97     97     - 
MDPPEHMHQRSM                   NOR_FUSOX        88     88     - 
YDPPEHTRLRKM                   O87675          100    100     - 
MDPPTHTAYRGL                   CPXL_PSESP      105    105     - 
HEGGEHARLRTI                   CPXP_RHISN       87     87     - 
MDAPDHMNQRGM                   NOR1_CYLTO       89     89     - 
HEGREHARLRAI                   CPXP_BRAJA       88     88     - 
MDAPHHTRLRKI                   P71856          119    119     - 
LDPPVHTQYRKV                   Q59723           94     94     - 
ADDPAHAVHRKL                   O33180          123    123     - 
 
Motif 2  width=17
Element                        Seqn Id          St    Int   Rpt 
DLVAMFARQLPVRVICE              Q59523          133     35     - 
DLIAHLALPLPVTVICE              O32460          145     35     - 
DLMESLAWPLPITVISE              O87605          143     36     - 
DLVTEFALPLPSLVICL              CPXF_STRGO      144     35     - 
DLVSQFALPVPSMVICR              CPXE_STRGO      144     35     - 
DLVSQFALPVPSMVICH              Q59831          149     35     - 
DLIDEFAFPLPITVISE              CPXK_SACER      142     34     - 
DLVEFLAVPFPVAVICE              Q59819          143     35     - 
DVVSDLAYPLPVIVIAE              Q59910          147     34     - 
DIMKSFASPLPFIVISE              O31785          142     34     - 
DIVDRFAHPLPIKVICE              CPXJ_SACER      139     34     - 
DLVHDFSYPLPVIVISE              O34374          130     34     - 
DLVTAFALPVPSMVICA              O85697          146     35     - 
NLVDDYAFPLPIIVISE              CPXY_BACSU      145     34     - 
DIIEDFAGPLPVIIIAE              CPXM_BACSU      132     34     - 
DLVDVLAFPLPVTIVAE              CPXQ_SACER      120     32     - 
ELVSAFALPVPSMVICA              CPXH_STRGR      152     35     - 
DLHREFALALPMLVFAE              CPXR_BRAJA      147     38     - 
DLVAFVADKVPGAVLCE              O87674          138     35     - 
DFVVEIAAELPMQMICI              YP22_MYCTU      144     34     - 
DVVMDFAKPLVLRMLGE              O52544          139     35     - 
EVISDFAFPLASFVIAN              BIOI_BACSU      130     34     - 
DIVASLASPLPIIVMAD              CPXM_BACME      137     34     - 
DLMDRYALPVSLLVLCE              FAS1_RHOFA      140     35     - 
DLMEDFALPLPIIMICE              Q54302          140     35     - 
DLIEFVADEVPGAVLCE              O52823          146     35     - 
DFVRDLAAPLPMAVIGD              O53563          124     34     - 
DLHRQFALALPMLVFAE              CPXR_RHISN      147     38     - 
DVVGRYCSQLPIVVISE              O08464          161     35     - 
DFVAEFAGKLPMDVISE              P77902          135     34     - 
DLIEKFALPVPSYIIYT              NOR2_CYLTO      144     37     - 
NIVDDLSSPFPSLVIAD              CPXI_BACME      138     34     - 
DFVARVSAPLPLITICE              O87192          142     35     - 
DLVESFCYPLPVTVICE              O52561          153     38     - 
DLVSELAGPLPLQIICD              YU44_MYCTU      162     37     - 
DVLEDFSYPLSIDVICE              Q60005          146     37     - 
DLVKEFALPVPSYIIYT              NOR_FUSOX       138     38     - 
DLQALFADPVGALALCE              O87675          147     35     - 
DFMTDCALYYPLHVVMT              CPXL_PSESP      152     35     - 
DLRRHLSFPLPAMVISA              CPXP_RHISN      134     35     - 
DLVKEFALPVPSYIIYT              NOR1_CYLTO      139     38     - 
DLRRHLSFPLPAMVISA              CPXP_BRAJA      135     35     - 
DFVEQVSCELPLQAIAG              P71856          165     34     - 
DLVPLLSAPLPLLTLAE              Q59723          140     34     - 
EWMGAMANRLPMMVVAE              O33180          169     34     - 
 
Motif 3  width=16
Element                        Seqn Id          St    Int   Rpt 
LLGVPSADHDRFTRWS               Q59523          150      0     - 
MLGVPPEDRPRFQDWT               O32460          162      0     - 
LLGVPEPDRAAFRVWT               O87605          160      0     - 
LLGVPYEDHAFFQERS               CPXF_STRGO      161      0     - 
LLGVPYADHEFFQDAS               CPXE_STRGO      161      0     - 
MLGVPYADHEFFQDAS               Q59831          166      0     - 
LMGVEDSRRDDFRSWT               CPXK_SACER      159      0     - 
LLGVPLEDRDLFRTFS               Q59819          160      0     - 
LLGIPAEDRDLFREWV               Q59910          164      0     - 
LMGIPKEDRSQFQIWT               O31785          159      0     - 
LLGVDEKYRGEFGRWS               CPXJ_SACER      156      0     - 
LLGVPSAHMEQFKAWS               O34374          147      0     - 
LLGVPYADHEFFEEQS               O85697          163      0     - 
MLGIPLEDRQKFRVWS               CPXY_BACSU      162      0     - 
MLGAPIEDRHLIKTYS               CPXM_BACSU      149      0     - 
LLGLPPMDHEQFGDWS               CPXQ_SACER      137      0     - 
LLGVPYADHAFFEERS               CPXH_STRGR      169      0     - 
LFGMPQDDMFELAAGI               CPXR_BRAJA      164      0     - 
LIGVPRDDRATFMQLC               O87674          155      0     - 
LLGVPETDRHWLFEAV               YP22_MYCTU      161      0     - 
LVGLPYEERDRYVPAV               O52544          156      0     - 
IIGVPEEDREQLKEWA               BIOI_BACSU      147      0     - 
LMGVPSKDRLLFKKWV               CPXM_BACME      154      0     - 
LLGVPYADRDELRDRT               FAS1_RHOFA      157      0     - 
LLGVPIEDQTKFRTWS               Q54302          157      0     - 
LIGVPRDDRAMFMQLC               O52823          163      0     - 
MLGVRPEQRDMFLRWS               O53563          141      0     - 
LFGMPQDDMFGLAAGI               CPXR_RHISN      164      0     - 
ILGVPEHDRPRVLEFG               O08464          178      0     - 
LIGVPDTDRARIRALA               P77902          152      0     - 
ILGVPFEDLEYLTEQN               NOR2_CYLTO      161      0     - 
LFGVPVKDRYQFKKWV               CPXI_BACME      155      0     - 
ALDIPEADRPWLRAHA               O87192          159      0     - 
LVGVDHEDRPQWRAWS               O52561          170      0     - 
MMGIPKADHQRIFHWT               YU44_MYCTU      179      0     - 
IVGIPEEAREQWHTWG               Q60005          163      0     - 
LLGVPFNDLEYLTQQN               NOR_FUSOX       155      0     - 
LLGIPRDDQREFVRRI               O87675          164      0     - 
ALGVPEDDEPLMLKLT               CPXL_PSESP      169      0     - 
LMGVLYEDHAFFAGLS               CPXP_RHISN      151      0     - 
ILGVPFNDLDHLTNQN               NOR1_CYLTO      156      0     - 
LMGVLYEDHAFFAGLS               CPXP_BRAJA      152      0     - 
LLGVPQEDRGKLFHWS               P71856          182      0     - 
LLGLDPDCWYELYNWT               Q59723          157      0     - 
LIGLPDPDIAQLVKWG               O33180          186      0     - 
 
Motif 4  width=23
Element                        Seqn Id          St    Int   Rpt 
AYMGDLIDRRRKEPTDDLVSALV        Q59523          188     22     - 
GYLAELIDAKTAAPADDLLSLLS        O32460          203     25     - 
GYLSRLIDSKRGQDGEDLLSALV        O87605          196     20     - 
EYLARLARTKRERPDDAIISRLV        CPXF_STRGO      198     21     - 
GYLDGLITQFQTEPGAGLVGALV        CPXE_STRGO      197     20     - 
RYLDGLITKLESEPGTGLLGKLV        Q59831          202     20     - 
EYLTELIAKKRTEPGDDLLTALL        CPXK_SACER      195     20     - 
VYMDGLVAQRRDAPTEDLLGALA        Q59819          198     22     - 
DYLYRRIALKRETPTDDLMSGLI        Q59910          210     30     - 
DYIAKLIHDRRIKPKDDLISKLV        O31785          197     22     - 
NFILDLVERRRTEPGDDLLSALI        CPXJ_SACER      194     22     - 
AFFAGIIEEKRNKPEQDIISILV        O34374          193     30     - 
AYLGELIDRKRRAPGEGLLDDLV        O85697          199     20     - 
EYLESLVRKKRREPAGDLISALI        CPXY_BACSU      202     24     - 
DYFRDILSKRRAEPKEDLMTMLL        CPXM_BACSU      195     30     - 
AYLKARCAERRADPGDDLISRLV        CPXQ_SACER      181     28     - 
EYLGALIDRKRAEPGDGLLDELI        CPXH_STRGR      205     20     - 
AYFGDLIQRKRTDPRRDIVSMLV        CPXR_BRAJA      207     27     - 
RYLLAMIARERKDPGEGLIGAVV        O87674          192     21     - 
TYALELIAGKRAEPADDMLSVVA        YP22_MYCTU      204     27     - 
KFFDEVIERRRQRPQDDLISSLV        O52544          193     21     - 
AYFKELIQKRKRHPQQDMISMLL        BIOI_BACSU      190     27     - 
QYLYPIVVQKRLNPADDIISDLL        CPXM_BACME      197     27     - 
RYMATLVTRAQEQPGDDLLGILA        FAS1_RHOFA      194     21     - 
LYLSELIAERRKQDTNDLLGSLV        Q54302          195     22     - 
RYLLAMIARERKDPGEGLIGAVI        O52823          200     21     - 
DFTRATIAARRADPTDDLVSVLV        O53563          184     27     - 
AYFGDLIQRKCIDPRHDIVATLV        CPXR_RHISN      207     27     - 
CWLEGHLQQLRHAPGDDLMSQLI        O08464          221     27     - 
RYYADLIAEFRRRPANNLTSALL        P77902          193     25     - 
KYLAKLVDQRLQEPKDDLIGRLV        NOR2_CYLTO      198     21     - 
QYLYPIVIEKRSNLSDDIISDLI        CPXI_BACME      198     27     - 
GYFQELTADRRRSPGEDLISTLA        O87192          197     22     - 
AAARGMIERRRAEPKDDMVTALV        O52561          205     19     - 
AYATALAEDRRVNHHDDLTSSLV        YU44_MYCTU      221     26     - 
DHLHLLIEQRRATPTGDLLTGLV        Q60005          198     19     - 
DYLAILVEQRLVEPKDDIISKLC        NOR_FUSOX       192     21     - 
RYLDNLIARQRRDADDGFLGMIV        O87675          201     21     - 
DYFNGFTVDRRSCPKDDVMSLLA        CPXL_PSESP      221     36     - 
AYIRGKMRDKRQDPGDNLLTDLL        CPXP_RHISN      191     24     - 
DYLASLVEKRLEEPKDDLISKLC        NOR1_CYLTO      193     21     - 
AYIRGKMRDKRQDPDDNLLTDLL        CPXP_BRAJA      192     24     - 
GYAMKMAEEKAKNPADDIVTQLI        P71856          222     24     - 
GFCQELFESRRANPGPDIATLLA        Q59723          199     26     - 
GYIFEQFDRAAADPRDNLLGELA        O33180          229     27     - 
 
Motif 5  width=12
Element                        Seqn Id          St    Int   Rpt 
SAVEELTRWVPL                   Q59523          269     58     - 
AAVEELLRYGQI                   O32460          283     57     - 
GAVEEMLRYEGP                   O87605          278     59     - 
GAVEELLRYLTI                   CPXF_STRGO      275     54     - 
GAVEELLRYLAI                   CPXE_STRGO      278     58     - 
GAVEELLRVLAI                   Q59831          283     58     - 
GAIEETLRYESP                   CPXK_SACER      276     58     - 
AAVEEMLRYTPL                   Q59819          279     58     - 
GAIEETLRYRSP                   Q59910          291     58     - 
TAVEELLRYTSP                   O31785          278     58     - 
NAVEEILRYIAP                   CPXJ_SACER      276     59     - 
QAVEEALRFRAP                   O34374          274     58     - 
GAVEELMRVLSI                   O85697          280     58     - 
SAIEEALRFHSP                   CPXY_BACSU      283     58     - 
NVIEETLRYYSP                   CPXM_BACSU      276     58     - 
AIVEEVLRYRPP                   CPXQ_SACER      262     58     - 
VVVEELLRFLSI                   CPXH_STRGR      286     58     - 
AFVEEVLRCDAP                   CPXR_BRAJA      289     59     - 
RAVDELIRYLTV                   O87674          271     56     - 
TAIEEIVRWTSP                   YP22_MYCTU      288     61     - 
AAIEELLRYLTV                   O52544          269     53     - 
TAVEECLRYESP                   BIOI_BACSU      270     57     - 
QAVEEMLRFRFN                   CPXM_BACME      279     59     - 
SGIEELLRWLSV                   FAS1_RHOFA      273     56     - 
KAVDELLRIIPI                   Q54302          276     58     - 
RAVDELIRYLTV                   O52823          279     56     - 
GAIEEMLRWTAP                   O53563          265     58     - 
AFVEEVLRCDAP                   CPXR_RHISN      289     59     - 
NTVEEILRLDSP                   O08464          305     61     - 
MWVEETLRYDTS                   P77902          274     58     - 
GFVEELCRYHTG                   NOR2_CYLTO      279     58     - 
KAVEEMLRYRFH                   CPXI_BACME      280     59     - 
RTLEELLRHIPF                   O87192          278     58     - 
QAVRELQRLGPI                   O52561          287     59     - 
TAVEEIVRWASP                   YU44_MYCTU      303     59     - 
QAVDELMRWCTP                   Q60005          280     59     - 
QFVEELCRYHTA                   NOR_FUSOX       273     58     - 
RVVNELLRYLSP                   O87675          280     56     - 
RLVDEAVRWTAP                   CPXL_PSESP      302     58     - 
KAVEEILRMYPP                   CPXP_RHISN      271     57     - 
QFVEELCRYHTA                   NOR1_CYLTO      274     58     - 
KAVQEILRMYPP                   CPXP_BRAJA      272     57     - 
TAADEIVRWATP                   P71856          301     56     - 
TATAEMVRHASP                   Q59723          280     58     - 
AFIEETLRYEPP                   O33180          309     57     - 
 
Motif 6  width=28
Element                        Seqn Id          St    Int   Rpt 
RYAVEDVTLRGVTIRAGEPVLASTGAAN   Q59523          288      7     - 
RIAVEDVEVGGTLVRAGEAVIPLFNAAN   O32460          302      7     - 
RFPVEPVDLDGTVIPAGDTVLVVLADAH   O87605          296      6     - 
RIATEDVLIGGRTIAAGEGVLCMISSAN   CPXF_STRGO      293      6     - 
RVATADIEVEGHLIRAGEGVIVVNSIAN   CPXE_STRGO      296      6     - 
RIATADIEIDGQLIRAGEGVIVTNSIAN   Q59831          301      6     - 
RHTAEAVRFGDVVIPEGELVWVALGAAN   CPXK_SACER      294      6     - 
RVATEDVELSTVTVRAGEPCVVHFASAN   Q59819          298      7     - 
RLLKEDTDILGHPMKAGQMVVAWIASAN   Q59910          308      5     - 
RWAIEDFTYKGHSIKRGDMIFIGIGSAN   O31785          296      6     - 
RFAAEEVEIGGVAIPQYSTVLVANGAAN   CPXJ_SACER      293      5     - 
RIAKRDTEIGGHLIKEGDMVLAFVASAN   O34374          291      5     - 
RMATEDIDVDGQTIRAGDGVVFSTSVIN   O85697          297      5     - 
RWTAEPFILHGQEIKRKDVIIISLASAN   CPXY_BACSU      301      6     - 
RVATEDTELGGVFIKKGSSVISWIASAN   CPXM_BACSU      293      5     - 
RTTTKATEVAGVPIPADVMVNTWVLSAN   CPXQ_SACER      279      5     - 
RLATEDMEVDGATIRKGEGVVFSTSLIN   CPXH_STRGR      303      5     - 
RIAQRDIELGGVVIPKNADVRVLIASGN   CPXR_BRAJA      308      7     - 
RIAKQDVTVGDQVIKAGESVICSLPAAN   O87674          289      6     - 
RTASRAVSLGGQPIEAGQKVVVWEGSAN   YP22_MYCTU      305      5     - 
RTALEDVKLEGELIKKGDTVTVSLPAAN   O52544          287      6     - 
RVASEDIDICGVTIRQGEQVYLLLGAAN   BIOI_BACSU      287      5     - 
RTVKEDNDLLGVELKEGDSVVVWMSAAN   CPXM_BACME      296      5     - 
RMAVTEVQIAGVTIPAGSFVIPSLLAAN   FAS1_RHOFA      291      6     - 
RMAVEDVELSGTIVKAGEAVAIQTHSAN   Q54302          295      7     - 
RIAMQDVIVASQMIKKGESVICSLPAAN   O52823          297      6     - 
RVLTADTEFHGTALCAGEKMMLLFESAN   O53563          282      5     - 
RIAQSDIELSGVVIPKNADVRVLIAAGN   CPXR_RHISN      308      7     - 
RVACRDVEVAGVRIKRGEVVVIYLAAAN   O08464          322      5     - 
RTVAHDLTLYDTTIPEGEVLLLLPGSAN   P77902          291      5     - 
RVAKEDMELGGKLIRAGEGIIASNQSAN   NOR2_CYLTO      297      6     - 
RTVKQDNELLGVKLKKGDVVIAWMSACN   CPXI_BACME      297      5     - 
RIALEDVELSGVLIKAGDVVHVSYLTAN   O87192          297      7     - 
RFATEDIEVGGTVIPRGMPVVPLIMAAN   O52561          304      5     - 
RTLTQDIELRGTKMAAGDKVSLWYCSAN   YU44_MYCTU      320      5     - 
RYATEDLDVGGVTVRKGEQVVAVIGAAG   Q60005          298      6     - 
RTAKEDVMIGDKLVRANEGIIASNQSAN   NOR_FUSOX       291      6     - 
SLAVKDVIIDGQLIKAGDYVLCSVLMAN   O87675          298      6     - 
RTALADTEVRGQNIKRGDRIMLSYPSAN   CPXL_PSESP      319      5     - 
RYPRTDVTIAGVHIPAESKVLVGLPATS   CPXP_RHISN      291      8     - 
RTAKVDLEIGGKHIKANEGIIASNQSAN   NOR1_CYLTO      292      6     - 
RYPRTDVTIAGEHIPAESKVLVGLPATS   CPXP_BRAJA      292      8     - 
RTALRDYELSGVQIKKGQRVVMFYRSAN   P71856          318      5     - 
RTAMEDTEIGGQAIAKGDKVVLWYASGN   Q59723          297      5     - 
RHVRNATTLDGTELPADSHLLLLWGAAN   O33180          326      5     - 
 
Motif 7  width=16
Element                        Seqn Id          St    Int   Rpt 
RDQAQFPDADRIDVDR               Q59523          316      0     - 
RDPEVFADPEELDLGR               O32460          330      0     - 
RTPERFPDPHRFDIRR               O87605          324      0     - 
RDAEVFPGGDDLDVAR               CPXF_STRGO      321      0     - 
RDGTVYEDPDALDIHR               CPXE_STRGO      324      0     - 
RDSSVFENPDRLDVHR               Q59831          329      0     - 
RDGERFEDPDRFDITR               CPXK_SACER      322      0     - 
RDEEVFDHADELDFHR               Q59819          326      0     - 
RDSAHFSDPDTFDVRR               Q59910          336      0     - 
RDPNFFENPEILNINR               O31785          324      0     - 
RDPKQFPDPHRFDVTR               CPXJ_SACER      321      0     - 
RDEAKFDRPHMFDIRR               O34374          319      0     - 
RDESVYPEPDALDWHR               O85697          325      0     - 
RDEKIFPNADIFDIER               CPXY_BACSU      329      0     - 
RDEDKFCKPDCFKIDR               CPXM_BACSU      321      0     - 
RDSDAHDDPDRFDPSR               CPXQ_SACER      307      0     - 
RDADVFPRAETLDWDR               CPXH_STRGR      331      0     - 
RDPDAFADPDRFDPAR               CPXR_BRAJA      336      0     - 
RDPALVPDADRLDVTR               O87674          317      0     - 
RDPSVFDRADEFDITR               YP22_MYCTU      333      0     - 
RDPAKFGCPAELDIER               O52544          315      0     - 
RDPSIFTNPDVFDITR               BIOI_BACSU      315      0     - 
MDEEMFEDPFTLNIHR               CPXM_BACME      324      0     - 
RDSNLTDRPDDLDITR               FAS1_RHOFA      319      0     - 
TDPKVYDHPEEIDFHR               Q54302          323      0     - 
RDPALVPDPNRLDVTR               O52823          325      0     - 
FDEAVFCEPEKFDVQR               O53563          310      0     - 
RDPDAFADPDRFDPAR               CPXR_RHISN      336      0     - 
RDPAVFPDPHRFDIER               O08464          350      0     - 
RDDRVFDDPDDYRIGR               P77902          319      0     - 
RDEDVFPNPDVFDMHR               NOR2_CYLTO      325      0     - 
MDETMFENPFSVDIHR               CPXI_BACME      325      0     - 
RDSAKFDRPDELDPDR               O87192          325      0     - 
SDPRKFPEPEKLQIDR               O52561          332      0     - 
RDESKFADPWTFDLAR               YU44_MYCTU      348      0     - 
HDPDRFPDPERFDITR               Q60005          326      0     - 
RDEEVFENPDEFNMNR               NOR_FUSOX       319      0     - 
RDEALTPNPNVFDANR               O87675          326      0     - 
RDEEVFSNPDEFDITR               CPXL_PSESP      347      0     - 
FDPRHFEDPEIFDIGR               CPXP_RHISN      319      0     - 
RDADIFENPDEFNMNR               NOR1_CYLTO      320      0     - 
FDPHHFDDPEIFDIER               CPXP_BRAJA      320      0     - 
FDEEVFQDPFTFNILR               P71856          346      0     - 
RDESVFSDADRFDVTR               Q59723          325      0     - 
RDPAQFEAPGEFRLDR               O33180          354      0     - 
 
Motif 8  width=10
Element                        Seqn Id          St    Int   Rpt 
LGFGHGVHHC                     Q59523          337      5     - 
IALGHGIHYC                     O32460          351      5     - 
LAFGHGIHFC                     O87605          345      5     - 
VAFGFGVHQC                     CPXF_STRGO      342      5     - 
LAFGFGVHQC                     CPXE_STRGO      345      5     - 
LSFGYGVHQC                     Q59831          350      5     - 
VAFGHGIHFC                     CPXK_SACER      343      5     - 
IAFGHGAHHC                     Q59819          347      5     - 
MSFGHGIHHC                     Q59910          357      5     - 
ISFGFGIHFC                     O31785          345      5     - 
LSFGQGIHFC                     CPXJ_SACER      342      5     - 
IAFGHGIHFC                     O34374          340      5     - 
VAFGFGIHQC                     O85697          346      5     - 
IAFGHGNHFC                     CPXY_BACSU      350      5     - 
LSFGFGIHFC                     CPXM_BACSU      342      5     - 
FSFGHGVHFC                     CPXQ_SACER      330      7     - 
LAFGFGVHQC                     CPXH_STRGR      352      5     - 
LSFGHGIHFC                     CPXR_BRAJA      367     15     - 
VAFGHGIHHC                     O87674          338      5     - 
LGFGQGVHYC                     YP22_MYCTU      354      5     - 
VAFGFGIHQC                     O52544          336      5     - 
LSFGHGHHVC                     BIOI_BACSU      336      5     - 
LTFGNGPHFC                     CPXM_BACME      346      6     - 
LAFGHGVHFC                     FAS1_RHOFA      340      5     - 
MSLGHGAHHC                     Q54302          344      5     - 
VAFGHGVHHC                     O52823          346      5     - 
LAFGFGTHFC                     O53563          331      5     - 
LSFGHGIHFC                     CPXR_RHISN      367     15     - 
LAFSTGRHFC                     O08464          372      6     - 
VSFGSGAHFC                     P77902          341      6     - 
LGFGFGPHRC                     NOR2_CYLTO      348      7     - 
LTFGNGPHFC                     CPXI_BACME      347      6     - 
MTFGWGAHHC                     O87192          346      5     - 
LGFGKGIHRC                     O52561          356      8     - 
GFGGGGAHFC                     YU44_MYCTU      370      6     - 
VGFGFGPHYC                     Q60005          351      9     - 
LGFGFGDHRC                     NOR_FUSOX       342      7     - 
VGFGHGIHYC                     O87675          347      5     - 
LGFGWGAHMC                     CPXL_PSESP      368      5     - 
LAFSYGPHYC                     CPXP_RHISN      340      5     - 
LGYGFGPHRC                     NOR1_CYLTO      343      7     - 
LAFSYGPHAC                     CPXP_BRAJA      341      5     - 
GFGGTGAHYC                     P71856          368      6     - 
VGFGSGQHVC                     Q59723          346      5     - 
ISFGKGAHFC                     O33180          376      6     - 
 
Motif 9  width=12
Element                        Seqn Id          St    Int   Rpt 
CLGAPLARVELQ                   Q59523          346     -1     - 
CLGAPLARLELQ                   O32460          360     -1     - 
CIGAPLARLEAR                   O87605          354     -1     - 
CLGQPLARVELQ                   CPXF_STRGO      351     -1     - 
CLGQNLARLELE                   CPXE_STRGO      354     -1     - 
CLGQNLARLELE                   Q59831          359     -1     - 
CVGAALARLEAQ                   CPXK_SACER      352     -1     - 
CIGAQLGRLELQ                   Q59819          356     -1     - 
CLGSFLARLEAK                   Q59910          366     -1     - 
CLGAPLARLEGH                   O31785          354     -1     - 
CMGRPLAKLEGE                   CPXJ_SACER      351     -1     - 
CLGAPLARLEAN                   O34374          349     -1     - 
CLGQNLARAELE                   O85697          355     -1     - 
CLGAQLARLEAK                   CPXY_BACSU      359     -1     - 
CLGAPLARLEAN                   CPXM_BACSU      351     -1     - 
CLGAPLARLENR                   CPXQ_SACER      339     -1     - 
CLGQNLARAELD                   CPXH_STRGR      361     -1     - 
CLGAQLARVQLA                   CPXR_BRAJA      376     -1     - 
CLGAALARLELR                   O87674          347     -1     - 
CLGANLARLELR                   YP22_MYCTU      363     -1     - 
CLGQNLARIELR                   O52544          345     -1     - 
CLGSSLARLEAQ                   BIOI_BACSU      345     -1     - 
CLGAPLARLEAK                   CPXM_BACME      355     -1     - 
CLGHSLARMTLR                   FAS1_RHOFA      349     -1     - 
CMGAQLVRVEMQ                   Q54302          353     -1     - 
CLGAALSRLELR                   O52823          355     -1     - 
CLGNQLARLELS                   O53563          340     -1     - 
CLGAQLARVQLA                   CPXR_RHISN      376     -1     - 
CLGAALARAEGE                   O08464          381     -1     - 
CLGAHLARMEAR                   P77902          350     -1     - 
CIAELLAKAELE                   NOR2_CYLTO      357     -1     - 
CLGAPLARLEMK                   CPXI_BACME      356     -1     - 
CLGAPLATMELE                   O87192          355     -1     - 
CLGQHVAYLEAE                   O52561          365     -1     - 
CLGANLARREIR                   YU44_MYCTU      379     -1     - 
CLGAALAHQETA                   Q60005          360     -1     - 
CIAEHLAKAELT                   NOR_FUSOX       351     -1     - 
CVGAALARSMLR                   O87675          356     -1     - 
CLGQHLAKLEMK                   CPXL_PSESP      377     -1     - 
CIGMALARLELK                   CPXP_RHISN      349     -1     - 
CIAEHLAKAELT                   NOR1_CYLTO      352     -1     - 
CIGVALARLELK                   CPXP_BRAJA      350     -1     - 
CIGANLARMTIN                   P71856          377     -1     - 
CVGSRLAEMQLR                   Q59723          355     -1     - 
CVGAALARLEAR                   O33180          385     -1     -