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PR00249

Identifier
GPCRSECRETIN  [View Relations]  [View Alignment]  
Accession
PR00249
No. of Motifs
7
Creation Date
27-JUL-1992  (UPDATE 19-JUN-1999)
Title
Secretin-like GPCR superfamily signature
Database References
PRINTS; PR90007 7TM; PR90006 GPCRCLAN; PR01694 BAIPRECURSOR
PRINTS; PR00361 CALCITONINR; PR01278 CD97PROTEIN; PR01279 CRFRECEPTOR
PRINTS; PR01127 DIUHORMONER; PR01128 EMR1HORMONER; PR01129 GIPRECEPTOR
PRINTS; PR01422 GPR56ORPHANR; PR01695 IGHEPTARCPTR; PR01444 LATROPHILIN
PRINTS; PR00393 PTRHORMONER; PR00490 SECRETINR; PR00491 VASOACTVEIPR

PROSITE; PS00649 G_PROTEIN_RECEP_F2_1; PS00650 G_PROTEIN_RECEP_F2_2
BLOCKS; BL00649
PFAM; PF00002 7tm_2
INTERPRO; IPR000832
GCRDB; GCR_0369
Literature References
1. ATTWOOD, T.K. AND FINDLAY, J.B.C.
Fingerprinting G protein-coupled receptors.
PROTEIN ENG. 7(2) 195-203 (1994). 
 
2. ISHIHARA T., NAKAMURA S., KAZIRO, Y., TAKAHASHI, T., TAKAHASHI, K.
AND NAGATA, S.
Molecular cloning and expression of a cDNA encoding the secretin receptor
EMBO J. 10 1635-1641 (1991).
 
3. LIN, H.Y., HARRIS, T.L., FLANNERY, M.S., ARUFFO, A., KAJI, E.H., 
GORN, A., KOLAKOWSKI, L.F., LODISH, H.F. AND GOLDRING, S.R.
Expression cloning of adenylate cyclase-coupled calcitonin receptor
SCIENCE 254 1022-1024 (1991).
 
4. JUEPPNER, H., ABOU-SAMRA, A.-B., FREEMAN, M., KONG, X.F., 
SCHIPANI, E., RICHARDS, J., KOLALOWSKI, L.F., HOCK, J., POTTS, J.T.,
KRONENBERG, H.M. AND SEGRE, G.E.
A G protein linked receptor for parathyroid hormone and parathyroid
hormone-related peptide.
SCIENCE 254 1024-1026 (1991).
 
5. ISHIHARA, T., SHIGEMOTO, R., MORI, K., TAKAHASHI, K. AND NAGATA, S.
Functional expression and tissue distribution of a novel receptor for
vasoactive intestinal polypeptide.
NEURON 8(4) 811-819 (1992).

Documentation
G protein-coupled receptors (GPCRs) constitute a vast protein family that 
encompasses a wide range of functions (including various autocrine, para-
crine and endocrine processes). They show considerable diversity at the 
sequence level, on the basis of which they can be separated into distinct 
groups. We use the term clan to describe the GPCRs, as they embrace a group
of families for which there are indications of evolutionary relationship, 
but between which there is no statistically significant similarity in 
sequence [1]. The currently known clan members include the rhodopsin-like 
GPCRs, the secretin-like GPCRs, the cAMP receptors, the fungal mating
pheromone receptors, and the metabotropic glutamate receptor family.
 
The secretin-like GPCRs include secretin [2], calcitonin [3], parathyroid
hormone/parathyroid hormone-related peptides [4] and vasoactive intestinal
peptide [5], all of which activate adenylyl cyclase and the phosphatidyl-
inositol-calcium pathway. The amino acid sequences of the receptors contain
high proportions of hydrophobic residues grouped into 7 domains, in a
manner reminiscent of the rhodopsins and other receptors believed to inter-
act with G proteins. However, while a similar 3D framework has been
proposed to account for this, there is no significant sequence similarity
between these families: the secretin-like receptors thus bear their own
unique `7TM' signature.
 
GPCRSECRETIN is a 7-element fingerprint that provides a signature for the 
secretin-like GPCR superfamily. The fingerprint was derived from an initial
alignment of 4 sequences: the motifs encode the 7 hydrophobic, membrane-
spanning regions (cf. PROSITE pattern PS00650 G_PROTEIN_RECEP_F2_2). A 
single iteration on OWL17.0 was required to reach convergence, no further
sequences being identified beyond the starting set. 
 
An update on SPTR37_9f identified a true set of 59 sequences, and 15
partial matches.
Summary Information
  59 codes involving  7 elements
0 codes involving 6 elements
1 codes involving 5 elements
2 codes involving 4 elements
1 codes involving 3 elements
10 codes involving 2 elements
Composite Feature Index
759595959595959
60000000
51011101
40122210
31010100
280102000
1234567
True Positives
CALR_CAVPO    CALR_HUMAN    CALR_MOUSE    CALR_PIG      
CALR_RABIT CALR_RAT CGRR_HUMAN CGRR_RAT
CRF2_HUMAN CRF2_MOUSE CRF2_RAT CRF2_XENLA
CRFR_CHICK CRFR_HUMAN CRFR_MOUSE CRFR_RAT
CRFR_SHEEP CRFR_XENLA DIHR_ACHDO DIHR_MANSE
GIPR_HUMAN GIPR_MESAU GIPR_RAT GLPR_HUMAN
GLPR_MOUSE GLPR_RAT GLR_HUMAN GLR_MOUSE
GLR_RAT GRFR_HUMAN GRFR_MOUSE GRFR_PIG
GRFR_RAT O43461 O73768 O73769
PACR_BOVIN PACR_HUMAN PACR_MOUSE PACR_RAT
PTH2_RAT PTR2_HUMAN PTRR_DIDMA PTRR_HUMAN
PTRR_MOUSE PTRR_PIG PTRR_RAT Q93245
Q99431 SCRC_HUMAN SCRC_RABIT SCRC_RAT
VIPR_CARAU VIPR_HUMAN VIPR_PIG VIPR_RAT
VIPS_HUMAN VIPS_MOUSE VIPS_RAT
True Positive Partials
Codes involving 5 elements
YQ44_CAEEL
Codes involving 4 elements
Q98955 YOW3_CAEEL
Codes involving 3 elements
EMR1_HUMAN
Codes involving 2 elements
CD97_HUMAN EMR1_MOUSE O00718 O88924
O88925 O88926 O88927 O88928
O88929 Q10922
Sequence Titles
CALR_CAVPO  CALCITONIN RECEPTOR PRECURSOR (CT-R) - CAVIA PORCELLUS (GUINEA PIG). 
CALR_HUMAN CALCITONIN RECEPTOR PRECURSOR (CT-R) - HOMO SAPIENS (HUMAN).
CALR_MOUSE CALCITONIN RECEPTOR PRECURSOR (CT-R) - MUS MUSCULUS (MOUSE).
CALR_PIG CALCITONIN RECEPTOR PRECURSOR (CT-R) - SUS SCROFA (PIG).
CALR_RABIT CALCITONIN RECEPTOR PRECURSOR (CT-R) - ORYCTOLAGUS CUNICULUS (RABBIT).
CALR_RAT CALCITONIN RECEPTOR PRECURSOR (CT-R) (C1A/C1B) - RATTUS NORVEGICUS (RAT).
CGRR_HUMAN CALCITONIN GENE-RELATED PEPTIDE TYPE 1 RECEPTOR PRECURSOR (CGRP TYPE 1 RECEPTOR) - HOMO SAPIENS (HUMAN).
CGRR_RAT CALCITONIN GENE-RELATED PEPTIDE TYPE 1 RECEPTOR PRECURSOR (CGRP TYPE 1 RECEPTOR) - RATTUS NORVEGICUS (RAT).
CRF2_HUMAN CORTICOTROPIN RELEASING FACTOR RECEPTOR 2 PRECURSOR (CRF-R) (CRF2) - HOMO SAPIENS (HUMAN).
CRF2_MOUSE CORTICOTROPIN RELEASING FACTOR RECEPTOR 2 PRECURSOR (CRF-R) (CRF2) (CRF-RB) (CRH-R2) - MUS MUSCULUS (MOUSE).
CRF2_RAT CORTICOTROPIN RELEASING FACTOR RECEPTOR 2 PRECURSOR (CRF-R) (CRF2) - RATTUS NORVEGICUS (RAT).
CRF2_XENLA CORTICOTROPIN RELEASING FACTOR RECEPTOR 2 PRECURSOR (CRF-R) (CRF2) - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
CRFR_CHICK CORTICOTROPIN RELEASING FACTOR RECEPTOR 1 PRECURSOR (CRF-R) (CRF1) - GALLUS GALLUS (CHICKEN).
CRFR_HUMAN CORTICOTROPIN RELEASING FACTOR RECEPTOR 1 PRECURSOR (CRF-R) (CRF1) - HOMO SAPIENS (HUMAN).
CRFR_MOUSE CORTICOTROPIN RELEASING FACTOR RECEPTOR 1 PRECURSOR (CRF-R) (CRF1) - MUS MUSCULUS (MOUSE).
CRFR_RAT CORTICOTROPIN RELEASING FACTOR RECEPTOR 1 PRECURSOR (CRF-R) (CRF1) - RATTUS NORVEGICUS (RAT).
CRFR_SHEEP CORTICOTROPIN RELEASING FACTOR RECEPTOR 1 PRECURSOR (CRF-R) (CRF1) - OVIS ARIES (SHEEP).
CRFR_XENLA CORTICOTROPIN RELEASING FACTOR RECEPTOR 1 PRECURSOR (CRF-R) (CRF1) - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
DIHR_ACHDO DIURETIC HORMONE RECEPTOR PRECURSOR (DH-R) - ACHETA DOMESTICUS (HOUSE CRICKET).
DIHR_MANSE DIURETIC HORMONE RECEPTOR (DH-R) - MANDUCA SEXTA (TOBACCO HAWKMOTH) (TOBACCO HORNWORM).
GIPR_HUMAN GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR PRECURSOR (GIP-R) (GLUCOSE- DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR) - HOMO SAPIENS (HUMAN).
GIPR_MESAU GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR PRECURSOR (GIP-R) (GLUCOSE- DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR) - MESOCRICETUS AURATUS (GOLDEN HAMSTER).
GIPR_RAT GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR PRECURSOR (GIP-R) (GLUCOSE- DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR) - RATTUS NORVEGICUS (RAT).
GLPR_HUMAN GLUCAGON-LIKE PEPTIDE 1 RECEPTOR PRECURSOR (GLP-1 RECEPTOR) (GLP-1-R) - HOMO SAPIENS (HUMAN).
GLPR_MOUSE GLUCAGON-LIKE PEPTIDE 1 RECEPTOR PRECURSOR (GLP-1 RECEPTOR) (GLP-1-R) - MUS MUSCULUS (MOUSE).
GLPR_RAT GLUCAGON-LIKE PEPTIDE 1 RECEPTOR PRECURSOR (GLP-1 RECEPTOR) (GLP-1-R) - RATTUS NORVEGICUS (RAT).
GLR_HUMAN GLUCAGON RECEPTOR PRECURSOR (GL-R) - HOMO SAPIENS (HUMAN).
GLR_MOUSE GLUCAGON RECEPTOR PRECURSOR (GL-R) - MUS MUSCULUS (MOUSE).
GLR_RAT GLUCAGON RECEPTOR PRECURSOR (GL-R) - RATTUS NORVEGICUS (RAT).
GRFR_HUMAN GROWTH HORMONE-RELEASING HORMONE RECEPTOR PRECURSOR (GHRH RECEPTOR) (GRF RECEPTOR) (GRFR) - HOMO SAPIENS (HUMAN).
GRFR_MOUSE GROWTH HORMONE-RELEASING HORMONE RECEPTOR PRECURSOR (GHRH RECEPTOR) (GRF RECEPTOR) (GRFR) - MUS MUSCULUS (MOUSE).
GRFR_PIG GROWTH HORMONE-RELEASING HORMONE RECEPTOR PRECURSOR (GHRH RECEPTOR) (GRF RECEPTOR) (GRFR) - SUS SCROFA (PIG).
GRFR_RAT GROWTH HORMONE-RELEASING HORMONE RECEPTOR PRECURSOR (GHRH RECEPTOR) (GRF RECEPTOR) (GRFR) - RATTUS NORVEGICUS (RAT).
O43461 CORTICOTROPIN RELEASING HORMONE RECEPTOR TYPE 2 GAMMA ISOFORM - HOMO SAPIENS (HUMAN).
O73768 GROWTH-HORMONE RELEASING HORMONE-LIKE PEPTIDE RECEPTOR - CARASSIUS AURATUS (GOLDFISH).
O73769 PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE 1 RECEPTOR PRECURSOR - CARASSIUS AURATUS (GOLDFISH).
PACR_BOVIN PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE I RECEPTOR PRECURSOR (PACAP TYPE I RECEPTOR) (PACAP-R-1) - BOS TAURUS (BOVINE).
PACR_HUMAN PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE I RECEPTOR PRECURSOR (PACAP TYPE I RECEPTOR) (PACAP-R-1) - HOMO SAPIENS (HUMAN).
PACR_MOUSE PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE I RECEPTOR PRECURSOR (PACAP TYPE I RECEPTOR) (PACAP-R-1) - MUS MUSCULUS (MOUSE).
PACR_RAT PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE IA RECEPTOR PRECURSOR (PACAP TYPE IA RECEPTOR) (PACAP-R-1) - RATTUS NORVEGICUS (RAT).
PTH2_RAT PARATHYROID HORMONE RECEPTOR PRECURSOR (PTH2 RECEPTOR) - RATTUS NORVEGICUS (RAT).
PTR2_HUMAN PARATHYROID HORMONE RECEPTOR PRECURSOR (PTH2 RECEPTOR) - HOMO SAPIENS (HUMAN).
PTRR_DIDMA PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR PRECURSOR (PTH/PTHR RECEPTOR) - DIDELPHIS MARSUPIALIS VIRGINIANA (NORTH AMERICAN OPOSSUM).
PTRR_HUMAN PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR PRECURSOR (PTH/PTHR RECEPTOR) - HOMO SAPIENS (HUMAN).
PTRR_MOUSE PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR PRECURSOR (PTH/PTHR RECEPTOR) - MUS MUSCULUS (MOUSE).
PTRR_PIG PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR PRECURSOR (PTH/PTHR RECEPTOR) - SUS SCROFA (PIG).
PTRR_RAT PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR PRECURSOR (PTH/PTHR RECEPTOR) - RATTUS NORVEGICUS (RAT).
Q93245 C18B12B.1.
Q99431 CORTICOTROPIN RELEASING HORMONE RECEPTOR TYPE 2 BETA ISOFORM (CRF2 RECEPTOR, BETA ISOFORM) - HOMO SAPIENS (HUMAN).
SCRC_HUMAN SECRETIN RECEPTOR PRECURSOR (SCT-R) - HOMO SAPIENS (HUMAN).
SCRC_RABIT SECRETIN RECEPTOR PRECURSOR (SCT-R) - ORYCTOLAGUS CUNICULUS (RABBIT).
SCRC_RAT SECRETIN RECEPTOR PRECURSOR (SCT-R) - RATTUS NORVEGICUS (RAT).
VIPR_CARAU VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR (VIP-R) (VIP RECEPTOR) - CARASSIUS AURATUS (GOLDFISH).
VIPR_HUMAN VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1 PRECURSOR (VIP-R-1) (PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE II RECEPTOR) (PACAP TYPE II RECEPTOR) (PACAP-R-2) - HOMO SAPIENS (HUMAN).
VIPR_PIG VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1 PRECURSOR (VIP-R-1) (PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE II RECEPTOR) (PACAP TYPE II RECEPTOR) (PACAP-R-2) - SUS SCROFA (PIG).
VIPR_RAT VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1 PRECURSOR (VIP-R-1) (PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE II RECEPTOR) (PACAP TYPE II RECEPTOR) (PACAP-R-2) - RATTUS NORVEGICUS (RAT).
VIPS_HUMAN VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2 PRECURSOR (VIP-R-2) (PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE III RECEPTOR) (PACAP TYPE III RECEPTOR) (PACAP-R-3) (HELODERMIN-PREFERRING VIP RECEPTOR) - HOMO SAPIENS (HUMAN).
VIPS_MOUSE VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2 PRECURSOR (VIP-R-2) (PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE III RECEPTOR) (PACAP TYPE III RECEPTOR) (PACAP-R-3) - MUS MUSCULUS (MOUSE).
VIPS_RAT VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2 PRECURSOR (VIP-R-2) (PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE TYPE III RECEPTOR) (PACAP TYPE III RECEPTOR) (PACAP-R-3) - RATTUS NORVEGICUS (RAT).

YQ44_CAEEL PROBABLE G PROTEIN-COUPLED RECEPTOR C13B9.4 IN CHROMOSOME III - CAENORHABDITIS ELEGANS.

Q98955 GLUCAGON RECEPTOR - MELEAGRIS GALLOPAVO (COMMON TURKEY).
YOW3_CAEEL PROBABLE G PROTEIN-COUPLED RECEPTOR ZK643.3 - CAENORHABDITIS ELEGANS.

EMR1_HUMAN CELL SURFACE GLYCOPROTEIN EMR1 PRECURSOR (EMR1 HORMONE RECEPTOR) - HOMO SAPIENS (HUMAN).

CD97_HUMAN LEUCOCYTE ANTIGEN CD97 PRECURSOR - HOMO SAPIENS (HUMAN).
EMR1_MOUSE CELL SURFACE GLYCOPROTEIN EMR1 PRECURSOR (EMR1 HORMONE RECEPTOR) (CELL SURFACE GLYCOPROTEIN F4/80) - MUS MUSCULUS (MOUSE).
O00718 CD97 - HOMO SAPIENS (HUMAN).
O88924 CL3AA - RATTUS NORVEGICUS (RAT).
O88925 CL3AB - RATTUS NORVEGICUS (RAT).
O88926 CL3AC - RATTUS NORVEGICUS (RAT).
O88927 CALCIUM-INDEPENDENT ALPHA-LATROTOXIN RECEPTOR 3 PRECURSOR (LATROPHILIN 3) (LRP3) (CIRL) (CL3) (LPH3) - Rattus norvegicus (Rat).
O88928 CL3BB - RATTUS NORVEGICUS (RAT).
O88929 CL3BC - RATTUS NORVEGICUS (RAT).
Q10922 HYPOTHETICAL 174.3 KD PROTEIN B0286.2 IN CHROMOSOME II - CAENORHABDITIS ELEGANS.
Scan History
OWL17_0    1  50   NSINGLE    
OWL18_0 1 50 NSINGLE
OWL19_1 1 50 NSINGLE
OWL20_1 1 50 NSINGLE
OWL21_1 1 100 NSINGLE
OWL23_2 2 100 NSINGLE
OWL28_0 1 200 NSINGLE
SPTR37_9f 3 80 NSINGLE
Initial Motifs
Motif 1  width=25
Element Seqn Id St Int Rpt
VMYTVGYSSSLAMLLVALSILCSFR SCRC_RAT 144 144 -
MIYTVGYSISLGSLTVAVLILGYFR PTRR_DIDMA 186 186 -
MIYTVGYSMSLASLTVAVLILAYFR PTRR_RAT 189 189 -
YLAIVGHSLSIFTLVISLGIFVFFR CALR_HUMAN 150 150 -

Motif 2 width=25
Element Seqn Id St Int Rpt
YIHMHLFVSFILRALSNFIKDAVLF SCRC_RAT 176 7 -
YIHMHLFVSFMLRAVSIFIKDAVLY PTRR_DIDMA 218 7 -
YIHMHMFLSFMLRAASIFVKDAVLY PTRR_RAT 221 7 -
TLHKNMFLTYILNSMIIIIHLVEVV CALR_HUMAN 198 23 -

Motif 3 width=24
Element Seqn Id St Int Rpt
LVMIFFQYCIMANYAWLLVEGLYL SCRC_RAT 217 16 -
VAVTVFLYFLTTNYYWILVEGLYL PTRR_DIDMA 277 34 -
VAVTFFLYFLATNYYWILVEGLYL PTRR_RAT 283 37 -
ILHFFHQYMMACNYFWMLCEGIYL CALR_HUMAN 237 14 -

Motif 4 width=26
Element Seqn Id St Int Rpt
LQAFVLLGWGSPAIFVALWAITRHFL SCRC_RAT 255 14 -
LWGFTLFGWGLPAVFVAVWVTVRATL PTRR_DIDMA 315 14 -
LWGFTIFGWGLPAVFVAVWVGVRATL PTRR_RAT 321 14 -
LRWYYLLGWGFPLVPTTIHAITRAVY CALR_HUMAN 275 14 -

Motif 5 width=26
Element Seqn Id St Int Rpt
WVIRGPVILSILINFIFFINILRILM SCRC_RAT 296 15 -
WIIQVPILAAIVVNFILFINIIRVLA PTRR_DIDMA 355 14 -
WIIQVPILASVVLNFILFINIIRVLA PTRR_RAT 361 14 -
YIIHGPVMAALVVNFFFLLNIVRVLV CALR_HUMAN 315 14 -

Motif 6 width=21
Element Seqn Id St Int Rpt
LAKSTLLLIPLFGIHYIVFAF SCRC_RAT 340 18 -
LLKSTLVLMPLFGVHYIVFMA PTRR_DIDMA 400 19 -
LLRSTLVLVPLFGVHYTVFMA PTRR_RAT 406 19 -
AVKATMILVPLLGIQFVVFPW CALR_HUMAN 357 16 -

Motif 7 width=22
Element Seqn Id St Int Rpt
LFFELALGSFQGLVVAVLYCFL SCRC_RAT 370 9 -
MHYEMLFNSFQGFFVAIIYCFC PTRR_DIDMA 435 14 -
MHYEMLFNSFQGFFVAIIYCFC PTRR_RAT 441 14 -
DYVMHSLIHFQGFFVATIYCFC CALR_HUMAN 389 11 -
Final Motifs
Motif 1  width=25
Element Seqn Id St Int Rpt
TGYTIGYSLSLASLLVAMAILSLFR VIPR_RAT 145 145 -
VMYTVGYSSSLAMLLVALSILCSFR SCRC_RAT 144 144 -
VMYTVGYSSSLVMLLVALGILCAFR SCRC_HUMAN 144 144 -
ALYTVGYSTSLATLTTAMVILCRFR PACR_RAT 154 154 -
ALYTVGYSTSLVTLTTAMVILCRFR PACR_MOUSE 155 155 -
ALYTVGYSTSLVTLTTAMVILCRFR PACR_HUMAN 155 155 -
ALYTVGYSTSLVSLTTAMVILCRFR O73769 147 147 -
ALYTVGYSTSLVTLTTAMVILCRFR PACR_BOVIN 172 172 -
VMYTVGYSSSLVMLLVALGILCAFR SCRC_RABIT 140 140 -
TGYTIGYGLSLATLLVATAILSLFR VIPR_HUMAN 144 144 -
TGYTIGYSLSLAALLVATAILSLFR VIPR_PIG 145 145 -
AIYTLGYSVSLMSLATGSIILCLFR VIPS_HUMAN 128 128 -
MIYTVGYSVSLASLTVAVLILAYFR PTRR_HUMAN 189 189 -
MIYTVGYSISLGSLTVAVLILGYFR PTRR_DIDMA 186 186 -
MIYTVGYSVSLASLTVAVLILAYFR PTRR_PIG 185 185 -
IGYTIGHSVSLISLTTAIVILCMSR VIPR_CARAU 105 105 -
AIYTLGYSVSLMSLTTGSIIICLFR VIPS_MOUSE 127 127 -
AIYTLGYSVSLMSLTTGSIIICLFR VIPS_RAT 127 127 -
MIYTVGYSMSLASLTVAVLILAYFR PTRR_MOUSE 189 189 -
MIYTVGYSMSLASLTVAVLILAYFR PTRR_RAT 189 189 -
QLYTAGYATSLISLITAVIIFTCFR O73768 138 138 -
VVYTVGYSLSLATLLLALLILSLFR GIPR_RAT 136 136 -
VMYTVGYSLSLATLLLALLILSLFR GIPR_HUMAN 139 139 -
VVYTVGYSLSLGTLLLALLILSLFR GIPR_MESAU 136 136 -
VMYTVGYSLSLGALLLALVILLGLR GLR_RAT 144 144 -
IIYTVGYALSFSALVIASAILVSFR GLPR_RAT 146 146 -
VMYTVGYSLSLGALLLALVILLGLR GLR_MOUSE 144 144 -
IIYTVGYALSFSALVIASAILVGFR GLPR_MOUSE 146 146 -
VMYTVGYSLSLGALLLALAILGGLS GLR_HUMAN 143 143 -
IIYTVGYALSFSALVIASAILLGFR GLPR_HUMAN 146 146 -
IINYLGHCISLVALLVAFVLFLRLR CRFR_MOUSE 121 121 -
IINYLGHCISLAALLVAFVLFLRLR CRFR_SHEEP 121 121 -
IINYLGHCISLVALLVAFVLFLRLR CRFR_HUMAN 121 121 -
IINYLGHCISLVALLVAFVLFLRLR CRFR_RAT 121 121 -
VINFLGHSISLCALLVAFILFLRLR CRFR_XENLA 121 121 -
IINYLGHCVSVVALVAAFLLFLVLR CRF2_RAT 118 118 -
VMYTVGYSISFGSLAVAILIIGYFR PTR2_HUMAN 146 146 -
IVYTTGHSVSAVALFVAIAILVALR GRFR_PIG 131 131 -
VVNYLGHCVSVAALVAAFLLFLALR Q99431 145 145 -
VVNYLGHCVSVAALVAAFLLFLALR O43461 104 104 -
VVNYLGHCVSVAALVAAFLLFLALR CRF2_HUMAN 118 118 -
IIYTVGHSISIVALFVAITILVALR GRFR_HUMAN 131 131 -
ILYTVGYSISFGSLAVAILIIGYFR PTH2_RAT 144 144 -
IIYTTGHSISIVALCVAIAILVALR GRFR_RAT 131 131 -
IVNYLGHCVSVVALVAAFLLFLVLR CRF2_MOUSE 138 138 -
IIYTTGHSISIVALCVAIAILVALR GRFR_MOUSE 131 131 -
IINYLGHCVSLGTLLVAFVLFMRLR CRFR_CHICK 126 126 -
IINYLGHCISILALVIAFLLFLCLR CRF2_XENLA 120 120 -
YLAIVGHSMSIITLVVSLGIFVYFR CALR_CAVPO 150 150 -
YLAIVGHSLSIFTLVISLGIFVFFR CALR_HUMAN 150 150 -
YLAIVGHSLSIFTLVISLGIFKCFR CALR_RABIT 150 150 -
YLALVGHSMSIAALIASMGIFLFFK CALR_RAT 150 150 -
YLALVGHSLSIAALVASMLIFWIFK CALR_MOUSE 150 150 -
YLAIVGHSLSILTLLISLGIFMFLR CALR_PIG 151 151 -
LIYLAGYSLSLAVLSLAVFVFLYFK DIHR_MANSE 88 88 -
YLTIIGHGLSIASLLISLGIFFYFK CGRR_HUMAN 143 143 -
YLTIIGHGLSIASLIISLIIFFYFK CGRR_RAT 143 143 -
FVFFVGFCLSLVAIAVAIWIFLYFK DIHR_ACHDO 135 135 -
SVSLTLSFVSVILLVAAIVLFSIFD Q93245 40 40 -

Motif 2 width=25
Element Seqn Id St Int Rpt
YIHMHLFMSFILRATAVFIKDMALF VIPR_RAT 177 7 -
YIHMHLFVSFILRALSNFIKDAVLF SCRC_RAT 176 7 -
YIHMHLFVSFILRALSNFIKDAVLF SCRC_HUMAN 176 7 -
FIHMNLFVSFMLRAISVFIKDWILY PACR_RAT 186 7 -
FIHMNLFVSFMLRAISVFIKDWILY PACR_MOUSE 187 7 -
FIHMNLFVSFMLRAISVFIKDWILY PACR_HUMAN 187 7 -
FIHMNLFVSFMLRAISVFIKDGVLY O73769 179 7 -
FIHMNLFVSFMLRAISVFIKDWILY PACR_BOVIN 204 7 -
YIHMHLFLSFILRALSNFIKDAVLF SCRC_RABIT 172 7 -
YIHMHLFISFILRAAAVFIKDLALF VIPR_HUMAN 176 7 -
YIHMHLFISFILRATAVFIKDLALF VIPR_PIG 177 7 -
YIHLNLFLSFILRAISVLVKDDVLY VIPS_HUMAN 160 7 -
YIHMHLFLSFMLRAVSIFVKDAVLY PTRR_HUMAN 221 7 -
YIHMHLFVSFMLRAVSIFIKDAVLY PTRR_DIDMA 218 7 -
YIHMHLFLSFMLRAVSIFVKDAVLY PTRR_PIG 217 7 -
YIHMHLFVSFILKAIAVFVKDAVLY VIPR_CARAU 137 7 -
YIHLNLFLSFMLRAISVLVKDSVLY VIPS_MOUSE 159 7 -
YIHLNLFLSFMLRAISVLVKDSVLY VIPS_RAT 159 7 -
YIHMHMFLSFMLRAASIFVKDAVLY PTRR_MOUSE 221 7 -
YIHMHMFLSFMLRAASIFVKDAVLY PTRR_RAT 221 7 -
YIHINLFVSFILRATAVFIKDAVLF O73768 170 7 -
YIHMNLFTSFMLRAGAILTRDQLLP GIPR_RAT 168 7 -
YIHINLFTSFMLRAAAILSRDRLLP GIPR_HUMAN 171 7 -
YIHMNVFLSFMLRAVAILTRDRLLP GIPR_MESAU 168 7 -
YIHGNLFASFVLKAGSVLVIDWLLK GLR_RAT 176 7 -
YIHLNLFASFILRALSVFIKDAALK GLPR_RAT 178 7 -
YIHGNLFASFVLKAGSVLVIDWLLK GLR_MOUSE 176 7 -
YIHLNLFASFILRALSVFIKDAALK GLPR_MOUSE 178 7 -
AIHANLFASFVLKASSVLVIDGLLR GLR_HUMAN 175 7 -
YIHLNLFASFILRALSVFIKDAALK GLPR_HUMAN 178 7 -
IIHWNLISAFILRNATWFVVQLTVS CRFR_MOUSE 153 7 -
IIHWNLISAFILRNATWFVVQLTMS CRFR_SHEEP 153 7 -
IIHWNLISAFILRNATWFVVQLTMS CRFR_HUMAN 182 36 -
IIHWNLISAFILRNATWFVVQLTVS CRFR_RAT 153 7 -
IIHWNLITAFILRNVTWFVMQLTLS CRFR_XENLA 153 7 -
VIHWNLITTFILRNITWFLLQLIDH CRF2_RAT 150 7 -
YIHMHLFVSFMLRATSIFVKDRVVH PTR2_HUMAN 178 7 -
YIHSQLFATFILKAGAVFLKDAALF GRFR_PIG 163 7 -
VIHWNLITTFILRNVMWFLLQLVDH Q99431 177 7 -
VIHWNLITTFILRNVMWFLLQLVDH O43461 136 7 -
VIHWNLITTFILRNVMWFLLQLVDH CRF2_HUMAN 150 7 -
YVHTQLFTTFILKAGAVFLKDAALF GRFR_HUMAN 163 7 -
YIHLHLFVSFMLRAXSIFVKDRVAQ PTH2_RAT 176 7 -
YIHTQLFATFILKASAVFLKDAAVF GRFR_RAT 163 7 -
VIHWNLITTFILRNIAWFLLQLIDH CRF2_MOUSE 170 7 -
YIHTQLFATFILKASAVFLKDAAIF GRFR_MOUSE 163 7 -
IIHWNLITAFILRNATWFVVQLTMN CRFR_CHICK 158 7 -
IIHWNLITTFILRNIMWFLLQMIDH CRF2_XENLA 152 7 -
TLHKNMFLTYILNSMIIIIHLVEVV CALR_CAVPO 182 7 -
TLHKNMFLTYILNSMIIIIHLVEVV CALR_HUMAN 198 23 -
TLHKNMFLTYILNSMIIIIHLVEVV CALR_RABIT 182 7 -
TLHKNMFLTYILNSIIIIIHLVEVV CALR_RAT 182 7 -
TLHKHMFLTYILNSIIIIIHLVEVV CALR_MOUSE 182 7 -
TLHKNMFLTYVLNSIIIIVHLVVIV CALR_PIG 199 23 -
TIHTNLMSTYILSACSWILNLVLQN DIHR_MANSE 120 7 -
TLHKNLFFSFVCNSVVTIIHLTAVA CGRR_HUMAN 175 7 -
TLHKNLFFSFVCNSIVTIIHLTAVA CGRR_RAT 175 7 -
TIHTNLMATYICNDATWIISAVVQE DIHR_ACHDO 167 7 -
SIHKNLATAFVFRFAVLAIWTIVQT Q93245 91 26 -

Motif 3 width=24
Element Seqn Id St Int Rpt
AAVVFFQYCVMANFFWLLVEGLYL VIPR_RAT 218 16 -
LVMIFFQYCIMANYAWLLVEGLYL SCRC_RAT 217 16 -
LVMVLFQYCIMANYSWLLVEGLYL SCRC_HUMAN 217 16 -
AVMVFFHYCVVSNYFWLFIEGLYL PACR_RAT 227 16 -
AVMVFFHYCVVSNYFWLFIEGLYL PACR_MOUSE 228 16 -
AVMVFFHYCVVSNYFWLFIEGLYL PACR_HUMAN 228 16 -
AVMVFFHYCVMSNYFWLFIEGLYL O73769 220 16 -
AVMVFFHYCVVSNYFWLFIEGLYL PACR_BOVIN 245 16 -
LVMVFFQYCIMANYAWLLVEGLYL SCRC_RABIT 213 16 -
AAMVFFQYCVMANFFWLLVEGLYL VIPR_HUMAN 217 16 -
AAVVLFQYCVMANFFWLLVEGLYL VIPR_PIG 218 16 -
LSLVFLQYCIMANFFWLLVEGLYL VIPS_HUMAN 204 19 -
VAVTFFLYFLATNYYWILVEGLYL PTRR_HUMAN 283 37 -
VAVTVFLYFLTTNYYWILVEGLYL PTRR_DIDMA 277 34 -
VAVTFFLYFLATNYYWILVEGLYL PTRR_PIG 278 36 -
AVIVFFQYCIMASFFWLLVEGLYL VIPR_CARAU 179 17 -
LSLVFFQYCIMANFYWLLVEGLYL VIPS_MOUSE 203 19 -
LSLVFFQYCIMANFYWLLVEGLYL VIPS_RAT 203 19 -
VAVTFFLYFLATNYYWILVEGLYL PTRR_MOUSE 283 37 -
VAVTFFLYFLATNYYWILVEGLYL PTRR_RAT 283 37 -
TAVTFFQFCILTNYFWLLVEGLYL O73768 211 16 -
TAQILTQYCVGANYTWLLVEGVYL GIPR_RAT 215 22 -
TAQIVTQYCVGANYTWLLVEGVYL GIPR_HUMAN 218 22 -
TAQIVTQYCVGANYTWLLVEGVYL GIPR_MESAU 215 22 -
VATVIMQYGIIANYCWLLVEGVYL GLR_RAT 227 26 -
LVFLLMQYCVAANYYWLLVEGVYL GLPR_RAT 228 25 -
VATVIMQYGIIPNYCWLLVEGVYL GLR_MOUSE 227 26 -
LVFLLMQYCVAANYYWLLVEGVYL GLPR_MOUSE 228 25 -
VAAVFMQYGIVANYCWLLVEGLYL GLR_HUMAN 226 26 -
LVFLLMQYCVAANYYWLLVEGVYL GLPR_HUMAN 228 25 -
LVTAAYNYFHVTNFFWMFGEGCYL CRFR_MOUSE 190 12 -
LVTAAYNYFHVTNFFWMFGEGCYL CRFR_SHEEP 190 12 -
LVTAAYNYFHVTNFFWMFGEGCYL CRFR_HUMAN 219 12 -
LVTAAYNYFHVTNFFWMFGEGCYL CRFR_RAT 190 12 -
LVTIAHNYFYVTNFFWMFGEGCYL CRFR_XENLA 190 12 -
CVTTIFNYFVVTNFFWMFVEGCYL CRF2_RAT 186 11 -
IAVVMFIYFLATNYYWILVEGLYL PTR2_HUMAN 238 35 -
VSVATSHFATMTNFSWLLAEAVYL GRFR_PIG 204 16 -
CITTIFNYFVVTNFFWMFVEGCYL Q99431 213 11 -
CITTIFNYFVVTNFFWMFVEGCYL O43461 172 11 -
CITTIFNYFVVTNFFWMFVEGCYL CRF2_HUMAN 186 11 -
VSVAASHFATMTNFSWLLAEAVYL GRFR_HUMAN 204 16 -
IAVVMFIYFLATNYYWILVEGLYL PTH2_RAT 236 35 -
VSVAVSHFATMTNFSWLLAEAVYL GRFR_RAT 204 16 -
CITTIFNYFVVTNFFWMFVEGCYL CRF2_MOUSE 206 11 -
VSVAISHLATMTNFSWLLAEAVYL GRFR_MOUSE 204 16 -
LVTAAYNYFHVTNFFWMFGEGCYL CRFR_CHICK 195 12 -
CITTIYNYFVVTNFFWMFVEGCYL CRF2_XENLA 188 11 -
ILHFFHQYMMACNYFWMLCEGIYL CALR_CAVPO 221 14 -
ILHFFHQYMMACNYFWMLCEGIYL CALR_HUMAN 237 14 -
VLHFFHQYMMSCNYFWMLCEGIYL CALR_RABIT 221 14 -
ILHFFHQYMMACNYFWMLCEGIYL CALR_RAT 258 51 -
VLHFLHQYMMSCNYFWMLCEGIYL CALR_MOUSE 258 51 -
VLHFFHQYMMSCNYFWMLCEGVYL CALR_PIG 238 14 -
ILVICMNYFYLTNFFWMLVEGLYL DIHR_MANSE 158 13 -
VSQFIHLYLMGCNYFWMLCEGIYL CGRR_HUMAN 214 14 -
VSQFIHLYLMGCNYFWMLCEGIYL CGRR_RAT 214 14 -
VLAVLMHYFYLTNFFWMFVEGLYL DIHR_ACHDO 201 9 -
AILWFVIYFNVASVMWMLIEGAFL Q93245 139 23 -

Motif 4 width=26
Element Seqn Id St Int Rpt
FWGYILIGWGVPSVFITIWTVVRIYF VIPR_RAT 256 14 -
LQAFVLLGWGSPAIFVALWAITRHFL SCRC_RAT 255 14 -
LQGFVAFGWGSPAIFVALWAIARHFL SCRC_HUMAN 255 14 -
FYWYTIIGWGTPTVCVTVWAVLRLYF PACR_RAT 265 14 -
FYWYTIIGWGTPTVCVTVWAVLRLYF PACR_MOUSE 266 14 -
FYWYTIIGWGTPTVCVTVWATLRLYF PACR_HUMAN 266 14 -
FYWYTIIGWGTPTICVTIWAVLRLHF O73769 258 14 -
FYWYIIIGWGTPTVCVSVWAMLRLYF PACR_BOVIN 283 14 -
LQGFVVLGWGSPAMFVTSWAVTRHFL SCRC_RABIT 251 14 -
FWGYILIGWGVPSTFTMVWTIARIHF VIPR_HUMAN 255 14 -
FWGYIFVGWGVPSTFIMVWTVVRIHF VIPR_PIG 256 14 -
FLAYLLIGWGLPTVCIGAWTAARLYL VIPS_HUMAN 241 13 -
LWGFTVFGWGLPAVFVAVWVSVRATL PTRR_HUMAN 321 14 -
LWGFTLFGWGLPAVFVAVWVTVRATL PTRR_DIDMA 315 14 -
LWGFTVFGWGLPAIFVAVWVSVRATL PTRR_PIG 316 14 -
FWWYILIGWGGPTIFIMAWSFAKAYF VIPR_CARAU 217 14 -
FLAYLLIGWGIPSVCIGAWTATRLSL VIPS_MOUSE 240 13 -
FLAYLLIGWGIPSVCIGAWIATRLSL VIPS_RAT 240 13 -
LWGFTIFGWGLPAVFVAVWVGVRATL PTRR_MOUSE 321 14 -
LWGFTIFGWGLPAVFVAVWVGVRATL PTRR_RAT 321 14 -
FWWYILIGWGVPSVVLIVWVLTRQFY O73768 249 14 -
FRCYLLLGWGAPALFVIPWVIVRYLY GIPR_RAT 253 14 -
FRYYLLLGWGAPALFVIPWVIVRYLY GIPR_HUMAN 256 14 -
FRCYLLLGWGAPALFVIPWVIVRYLL GIPR_MESAU 253 14 -
FSLYLCIGWGSPLLFVIPWVVVKCLF GLR_RAT 265 14 -
FKLYLSIGWGVPLLFVIPWGIVKYLY GLPR_RAT 266 14 -
FSLYLGIGWGAPLLFVIPWVVVKCLF GLR_MOUSE 265 14 -
FKLYLSIGWGVPLLFVIPWGIVKYLY GLPR_MOUSE 266 14 -
FSLYLGIGWGAPMLFVVPWAVVKCLF GLR_HUMAN 264 14 -
FRLYVSIGWGVPLLFVVPWGIVKYLY GLPR_HUMAN 266 14 -
KWMFVCIGWGVPFPIIVAWAIGKLYY CRFR_MOUSE 228 14 -
KWMFICIGWGVPFPIIVAWAIGKLYY CRFR_SHEEP 228 14 -
KWMFICIGWGVPFPIIVAWAIGKLYY CRFR_HUMAN 257 14 -
KWMFVCIGWGVPFPIIVAWAIGKLHY CRFR_RAT 228 14 -
KWMFICIGWCIPFPIIVAWAIGKLYY CRFR_XENLA 228 14 -
KWLFLFIGWCIPCPIIVAWAVGKLYY CRF2_RAT 224 14 -
LWGFILIGWGFPAAFVAAWAVARATL PTR2_HUMAN 276 14 -
FWWLVLAGWGLPLLFTGTWVGCKLAF GRFR_PIG 242 14 -
KCLFLFIGWCIPFPIIVAWAIGKLYY Q99431 251 14 -
KCLFLFIGWCIPFPIIVAWAIGKLYY O43461 210 14 -
KCLFLFIGWCIPFPIIVAWAIGKLYY CRF2_HUMAN 224 14 -
FWWLVLAGWGLPVLFTGTWVSCKLAF GRFR_HUMAN 242 14 -
LWGFILIGWGFPAVFVVAWAVARATL PTH2_RAT 274 14 -
FWWLVLAGWGLPVLCTGTWVGCKLAF GRFR_RAT 242 14 -
KWLFLFIGWCIPCPIIIAWAVGKLYY CRF2_MOUSE 244 14 -
FWWLVLAGWGLPVLCTGTWVGCKHSF GRFR_MOUSE 242 14 -
KWMFICIGWCIPFPIIVAWAIGKLYY CRFR_CHICK 233 14 -
KWVFLFIGWCIPSPIIVTWAICKLFY CRF2_XENLA 226 14 -
LRWYYLLGWGFPLVPTTIHAITRALY CALR_CAVPO 259 14 -
LRWYYLLGWGFPLVPTTIHAITRAVY CALR_HUMAN 275 14 -
LRWYYLLGWGFPLVPTTIHAITRAIY CALR_RABIT 259 14 -
LRWYYLLGWGFPIVPTIIHAITRAVY CALR_RAT 296 14 -
LRWYYLLGWGFPIVPTIIHAITRALY CALR_MOUSE 296 14 -
LWWYHVLGWGFPLIPTTAHAITRAVL CALR_PIG 276 14 -
LKVYTTIGWGAPAVFITIWVISRCFV DIHR_MANSE 196 14 -
LMWYYFLGWGFPLIPACIHAIARSLY CGRR_HUMAN 252 14 -
LMWYYFLGWGFPLLPACIHAIARSLY CGRR_RAT 252 14 -
LQIYIIIGWGIPGVIVVTWAIIKHLG DIHR_ACHDO 239 14 -
WSLYLACGWGVPFVVVTAWALVHQYI Q93245 178 15 -

Motif 5 width=26
Element Seqn Id St Int Rpt
WIIKAPILLSILVNFVLFICIIRILV VIPR_RAT 297 15 -
WVIRGPVILSILINFIFFINILRILM SCRC_RAT 296 15 -
WIIRGPVILSILINFILFINILRILM SCRC_HUMAN 296 15 -
WVIKGPVVGSIMVNFVLFIGIIIILV PACR_RAT 306 15 -
WVIKGPVVGSIMVNFVLFIGIIIILV PACR_MOUSE 307 15 -
WVIKGPVVGSIMVNFVLFIGIIVILV PACR_HUMAN 307 15 -
WVIKGPVVASIMINFVLFIGIIIILV O73769 299 15 -
WVIKGPVVGSIMVNFVLFIGIIVILV PACR_BOVIN 324 15 -
WVIRGPVILSILINFILFINILRILT SCRC_RABIT 292 15 -
WIIKGPILTSILVNFILFICIIRILL VIPR_HUMAN 295 14 -
WIIKAPILASILVNFILFIRIIGILV VIPR_PIG 296 14 -
WVIRIPILISIIVNFVLFISIIRILL VIPS_HUMAN 282 15 -
WIIQVPILASIVLNFILFINIVRVLA PTRR_HUMAN 361 14 -
WIIQVPILAAIVVNFILFINIIRVLA PTRR_DIDMA 355 14 -
WIIQVPILASIVLNFILFINIVRVLA PTRR_PIG 356 14 -
WIIKTPILASILMNFILFICIIRILR VIPR_CARAU 259 16 -
WVIRMPILISIVVNFALFISIVRILL VIPS_MOUSE 281 15 -
WVIRMPILISIVVNFALFISIVRILL VIPS_RAT 281 15 -
WIIQVPILASVVLNFILFINIIRVLA PTRR_MOUSE 361 14 -
WIIQVPILASVVLNFILFINIIRVLA PTRR_RAT 361 14 -
WIIKGPITVSLIANIIIFLNVIRILV O73768 290 15 -
WIIRTPILITILINFLIFIRILGILV GIPR_RAT 294 15 -
WIIRTPILMTILINFLIFIRILGILL GIPR_HUMAN 297 15 -
WIIRTPILITILINFFIFIRILGILV GIPR_MESAU 294 15 -
WILRIPVLLAILINFFIFVRIIHLLV GLR_RAT 306 15 -
LIIRLPILFAIGVNFLVFIRVICIVI GLPR_RAT 307 15 -
WILRIPVFLALLINFFIFVHIIQLLV GLR_MOUSE 306 15 -
LIIRLPILFAIGVNFLIFIRVICIVV GLPR_MOUSE 307 15 -
WILRFPVFLAILINFFIFVRIVQLLV GLR_HUMAN 305 15 -
LIIRLPILFAIGVNFLIFVRVICIVV GLPR_HUMAN 307 15 -
YIYQGPMILVLLINFIFLFNIVRILM CRFR_MOUSE 270 16 -
YIYQGPMILVLLINFIFLFNIVRILM CRFR_SHEEP 270 16 -
YIYQGPMILVLLINFIFLFNIVRILM CRFR_HUMAN 299 16 -
YIYQGPMILVLLINFIFLFNIVRILM CRFR_RAT 270 16 -
FIYQGPVILVLLINFIFLFNIVRILM CRFR_XENLA 270 16 -
YIYQGPIILVLLINFVFLFNIVRILM CRF2_RAT 266 16 -
WIYQAPILAAIGLNFILFLNTVRVLA PTR2_HUMAN 316 14 -
WIIKGPIVLSVGVNFGLFLNIIRILL GRFR_PIG 283 15 -
YIYQGPIILVLLINFVFLFNIVRILM Q99431 293 16 -
YIYQGPIILVLLINFVFLFNIVRILM O43461 252 16 -
YIYQGPIILVLLINFVFLFNIVRILM CRF2_HUMAN 266 16 -
WIIKGPIVLSVGVNFGLFLNIIRILV GRFR_HUMAN 283 15 -
WIYXXPILAAIGLNFILFLNTVRVLA PTH2_RAT 313 13 -
WIIKGPIVLSVGVNFGLFLNIICILL GRFR_RAT 283 15 -
YIYQGPVMLVLLINFVFLFNIVRILM CRF2_MOUSE 286 16 -
WIIKGPIVLSVGVNFGLFLNIICILL GRFR_MOUSE 283 15 -
YIYQGPMILVLLINFIFLFNIVRILM CRFR_CHICK 275 16 -
YIYQGRVILVLLINFVFLFNIVRILM CRF2_XENLA 268 16 -
YIIHGPVMVALVVNFFFLLNIVRVLV CALR_CAVPO 299 14 -
YIIHGPVMAALVVNFFFLLNIVRVLV CALR_HUMAN 315 14 -
YIIHGPVMAALVVNFFFLLNIVRVLV CALR_RABIT 299 14 -
YIIHGPVMAALVVNFFFLLNIVRVLV CALR_RAT 336 14 -
YIIHGPVMVALVVNFFFLLNIVRVLV CALR_MOUSE 336 14 -
YIIHGPVMAALVVNFFFLLNILRVLV CALR_PIG 316 14 -
WIHKAPALVGLALNLFFLIRIMWVLI DIHR_MANSE 251 29 -
YIIHGPICAALLVNLFFLLNIVRVLI CGRR_HUMAN 292 14 -
YIIHGPICAALLVNLFFLLNIVRVLI CGRR_RAT 292 14 -
WIHQAPVITVLAVNLVFLFSIMWVLI DIHR_ACHDO 294 29 -
WILAGTMGSALIMNLIFLLMIVVILV Q93245 223 19 -

Motif 6 width=21
Element Seqn Id St Int Rpt
LAKSTLLLIPLFGIHYVMFAF VIPR_RAT 341 18 -
LAKSTLLLIPLFGIHYIVFAF SCRC_RAT 340 18 -
LARSTLLLIPLFGIHYIVFAF SCRC_HUMAN 340 18 -
LARSTLLLIPLFGIHYTVFAF PACR_RAT 406 74 -
LARSTLLLIPLFGIHYTVFAF PACR_MOUSE 379 46 -
LARSTLLLIPLFGIHYTVFAF PACR_HUMAN 351 18 -
LARSTLLLIPLFGIHYTVFAF O73769 343 18 -
LARSTLLLIPLFGIHYTVFAF PACR_BOVIN 396 46 -
LARSTLLLIPLFGVHYIVFVF SCRC_RABIT 336 18 -
LARSTLLLIPLFGVHYIMFAF VIPR_HUMAN 339 18 -
LAKSTLLLIPLFGVHYIMFAF VIPR_PIG 340 18 -
LAKSTLLLIPLFGVHYMVFAV VIPS_HUMAN 326 18 -
LLKSTLVLMPLFGVHYIVFMA PTRR_HUMAN 406 19 -
LLKSTLVLMPLFGVHYIVFMA PTRR_DIDMA 400 19 -
LLKSTLVLMPLFGVHYIVFMA PTRR_PIG 401 19 -
LAKSTLLLIPLFGINFIIFAF VIPR_CARAU 303 18 -
LAKSTLLLIPLFGVHYMVFAA VIPS_MOUSE 325 18 -
LAKSTLLLIPLFGVHYMVFAA VIPS_RAT 325 18 -
LLRSTLVLVPLFGVHYTVFMA PTRR_MOUSE 406 19 -
LLRSTLVLVPLFGVHYTVFMA PTRR_RAT 406 19 -
LAKSTLFLIPLFGMHYTLFAF O73768 334 18 -
LARSTLTLMPLLGVHEVVFAP GIPR_RAT 336 16 -
LARSTLTLVPLLGVHEVVFAP GIPR_HUMAN 339 16 -
LARSTLTLVPLLGVHEVVFAP GIPR_MESAU 336 16 -
LARSTLTLIPLLGVHEVVFAF GLR_RAT 348 16 -
LAKSTLTLIPLLGTHEVIFAF GLPR_RAT 349 16 -
LARSTLTLIPLLGVHEVVFAF GLR_MOUSE 348 16 -
LAKSTLTLIPLLGTHEVIFAF GLPR_MOUSE 349 16 -
LAKSTLTLIPLLGVHEVVFAF GLR_HUMAN 347 16 -
LAKSTLTLIPLLGTHEVIFAF GLPR_HUMAN 349 16 -
AVKATLVLLPLLGITYMLFFV CRFR_MOUSE 312 16 -
AVKATLVLLPLLGITYMLFFV CRFR_SHEEP 312 16 -
AVKATLVLLPLLGITYMLFFV CRFR_HUMAN 341 16 -
AVKATLVLLPLLGITYMLFFV CRFR_RAT 312 16 -
AVKATLVLLPLLGITYMLFFV CRFR_XENLA 312 16 -
AVKATLVLLPLLGITYMLFFV CRF2_RAT 308 16 -
LAKSTLVLVLVFGVHYIVFVC PTR2_HUMAN 361 19 -
LSKSTLLLIPLFGIHYVIFNF GRFR_PIG 327 18 -
AVKATLVLLPLLGITYMLFFV Q99431 335 16 -
AVKATLVLLPLLGITYMLFFV O43461 294 16 -
AVKATLVLLPLLGITYMLFFV CRF2_HUMAN 308 16 -
LSKSTLFLIPLFGIHYIIFNF GRFR_HUMAN 327 18 -
LAKSTLVLVLVFGVHYIVFIC PTH2_RAT 358 19 -
LSKSTLLLIPLFGIHYIIFNF GRFR_RAT 368 59 -
AVKATLVLLPLLGITYMLFFV CRF2_MOUSE 328 16 -
LSKSTLLLIPLFGIHYIIFNF GRFR_MOUSE 327 18 -
AVKATLVLLSLLGITYMLFFV CRFR_CHICK 317 16 -
AVKATLVLLPLLGITYMLFFV CRF2_XENLA 310 16 -
AVKATMILVPLLGIQFVVFPW CALR_CAVPO 341 16 -
AVKATMILVPLLGIQFVVFPW CALR_HUMAN 357 16 -
AVKATMILVPLLGIQFVVFPW CALR_RABIT 341 16 -
AVKATMVLVPLLGIQFVVFPW CALR_RAT 378 16 -
AVKATMVLVPLLGIQFVVFPW CALR_MOUSE 378 16 -
AVRATLILVPLLGVQFVVLPW CALR_PIG 358 16 -
ATKALLVLIPLLGITNLLVLC DIHR_MANSE 293 16 -
AVRATLILVPLLGIEFVLIPW CGRR_HUMAN 334 16 -
AVRATLILVPLLGIEFVLFPW CGRR_RAT 334 16 -
ATKALLVLFPLLGITYILMMQ DIHR_ACHDO 336 16 -
TIKATLLLVPLLGISNIPLFY Q93245 265 16 -

Motif 7 width=22
Element Seqn Id St Int Rpt
MVFELVVGSFQGFVVAILYCFL VIPR_RAT 372 10 -
LFFELALGSFQGLVVAVLYCFL SCRC_RAT 370 9 -
LFFELALGSFQGLVVAVLYCFL SCRC_HUMAN 370 9 -
LVFELGLGSFQGFVVAVLYCFL PACR_RAT 437 10 -
LVFELGLGSFQGFVVAVLYCFL PACR_MOUSE 410 10 -
LVFELGLGSFQGFVVAVLYCFL PACR_HUMAN 382 10 -
LVFELGLGSFQGFVVAVLYCFL O73769 374 10 -
LVFELGLGSFQGFVVAVLYCFL PACR_BOVIN 427 10 -
LFFELALGSFQGLVVAVLYCFL SCRC_RABIT 366 9 -
MVFELVVGSFQGFVVAILYCFL VIPR_HUMAN 370 10 -
MVFELIVGSFQGCVVAILYCFL VIPR_PIG 371 10 -
ILFELCLGSFQGLVVAVLYCFL VIPS_HUMAN 357 10 -
MHYEMLFNSFQGFFVAIIYCFC PTRR_HUMAN 441 14 -
MHYEMLFNSFQGFFVAIIYCFC PTRR_DIDMA 435 14 -
MHYEMLFNSFQGFFVAIIYCFC PTRR_PIG 436 14 -
LVFDLILGSFQGFVVAVLYCFL VIPR_CARAU 334 10 -
ILFELCVGSFQGLVVAVLYCFL VIPS_MOUSE 356 10 -
ILFELCVGSFQGLVVAVLYCFL VIPS_RAT 356 10 -
MHYEMLFNSFQGFFVAIIYCFC PTRR_MOUSE 441 14 -
MHYEMLFNSFQGFFVAIIYCFC PTRR_RAT 441 14 -
FYIELGLGSFQGFVVALLYCFL O73768 365 10 -
LAFEIFLSSFQGFLVSVLYCFI GIPR_RAT 371 14 -
LGFEIFLSSFQGFLVSVLYCFI GIPR_HUMAN 374 14 -
LAFEIFLSSFQGFLVSVLYCFI GIPR_MESAU 371 14 -
LFFDLFFSSFQGLLVAVLYCFL GLR_RAT 383 14 -
LFTELSFTSFQGFMVAVLYCFV GLPR_RAT 384 14 -
LFFDLFLSSFQGLLVAVLYCFL GLR_MOUSE 383 14 -
LFTELSFTSFQGLMVAILYCFV GLPR_MOUSE 384 14 -
LFFDLFLSSFQGLLVAVLYCFL GLR_HUMAN 382 14 -
LFTELSFTSFQGLMVAILYCFV GLPR_HUMAN 384 14 -
IYFNSFLESFQGFFVSVFYCFL CRFR_MOUSE 345 12 -
IYFNSFLESFQGFFVSVFYCFL CRFR_SHEEP 345 12 -
IYFNSFLESFQGFFVSVFYCFL CRFR_HUMAN 374 12 -
IYFNSFLESFQGFFVSVFYCFL CRFR_RAT 345 12 -
IYFNSFLQSFQGFFVSVFYCFL CRFR_XENLA 345 12 -
IYFNSFLQSFQGFFVSVFYCFF CRF2_RAT 341 12 -
MHCELFFNSFQGFFVSIIYCYC PTR2_HUMAN 395 13 -
LPLELGLGSFQGFIVAILYCFL GRFR_PIG 358 10 -
IYFNSFLQSFQGFFVSVFYCFF Q99431 368 12 -
IYFNSFLQSFQGFFVSVFYCFF O43461 327 12 -
IYFNSFLQSFQGFFVSVFYCFF CRF2_HUMAN 341 12 -
LPLELGLGSFQGFIVAILYCFL GRFR_HUMAN 358 10 -
MHCELFFNSFQGFFVSIVYCYC PTH2_RAT 392 13 -
LPLELGLGSFQGFVVAVLYCFL GRFR_RAT 399 10 -
IYFNSFLQSFQGFFVSVFYCFF CRF2_MOUSE 361 12 -
VPLELGLGSFQGFIVAVLYCFL GRFR_MOUSE 358 10 -
IYFNSFLESFQGFFVSVFYCFL CRFR_CHICK 350 12 -
IYFNSFLQSFQGFFVSVFYCFL CRF2_XENLA 343 12 -
DYFMHSLIHFQGFFVATIYCFC CALR_CAVPO 373 11 -
DYVMHSLIHFQGFFVATIYCFC CALR_HUMAN 389 11 -
DYLMHSLIHFQGFFVATIYCFC CALR_RABIT 373 11 -
DYLMHSLIHFQGFFVATIYCFC CALR_RAT 410 11 -
DYLMHSLIHFQGFFVATIYCFC CALR_MOUSE 410 11 -
DYVVHSLIHFQGFFVAIIYCFC CALR_PIG 390 11 -
DYTRALMLSTQGFTVALFYCFM DIHR_MANSE 326 12 -
DYIMHILMHFQGLLVSTIFCFF CGRR_HUMAN 366 11 -
DYVMHILMHYQGLLVSTIFCFF CGRR_RAT 366 11 -
RNAQALLLSLQGFTVALFYCFL DIHR_ACHDO 368 11 -
MLGSAILQHSQGIFIAVLYCFL Q93245 295 9 -