SPRINT Home UMBER Home Contents Standard Search Advanced Search Relation Search

==SPRINT==> PRINTS View



  selected as


PR00243

Identifier
MUSCARINICR  [View Relations]  [View Alignment]  
Accession
PR00243
No. of Motifs
9
Creation Date
13-JUL-1994  (UPDATE 03-JUL-1999)
Title
Muscarinic acetylcholine receptor signature
Database References
PRINTS; PR90007 7TM; PR90006 GPCRCLAN; PR00237 GPCRRHODOPSN
PRINTS; PR00538 MUSCRINICM1R; PR00539 MUSCRINICM2R; PR00540 MUSCRINICM3R
PRINTS; PR00541 MUSCRINICM4R; PR00542 MUSCRINICM5R
INTERPRO; IPR000995
GCRDB; GCR_0010
Literature References
1. ATTWOOD, T.K. AND FINDLAY, J.B.C. 
Fingerprinting G protein-coupled receptors.
PROTEIN ENG. 7(2) 195-203 (1994).
 
2. ATTWOOD, T.K. AND FINDLAY, J.B.C. 
G protein-coupled receptor fingerprints.
7TM, VOLUME 2, EDS. G.VRIEND AND B.BYWATER (1993).
 
3. BIRNBAUMER, L.
G proteins in signal transduction.
ANNU.REV.PHARMACOL.TOXICOL. 30 675-705 (1990).
 
4. CASEY, P.J. AND GILMAN, A.G.
G protein involvement in receptor-effector coupling.
J.BIOL.CHEM. 263(6) 2577-2580 (1988).
 
5. ATTWOOD, T.K. AND FINDLAY, J.B.C. 
Design of a discriminating fingerprint for G protein-coupled receptors.
PROTEIN ENG. 6(2) 167-176 (1993).
 
6. KERLAVAGE, A.R., FRASER, C.M., CHUNG, F-Z. AND VENTER, J.C.
Molecular structure and evolution of adrenergic and cholinergic receptors.
PROTEINS 1 287-301 (1986).

Documentation
G protein-coupled receptors (GPCRs) constitute a vast protein family that 
encompasses a wide range of functions (including various autocrine, para-
crine and endocrine processes). They show considerable diversity at the 
sequence level, on the basis of which they can be separated into distinct 
groups. We use the term clan to describe the GPCRs, as they embrace a group
of families for which there are indications of evolutionary relationship, 
but between which there is no statistically significant similarity in 
sequence [1]. The currently known clan members include the rhodopsin-like 
GPCRs, the secretin-like GPCRs, the cAMP receptors, the fungal mating
pheromone receptors, and the metabotropic glutamate receptor family.
 
The rhodopsin-like GPCRs themselves represent a widespread protein family 
that includes hormone, neurotransmitter and light receptors, all of
which transduce extracellular signals through interaction with guanine
nucleotide-binding (G) proteins. Although their activating ligands vary 
widely in structure and character, the amino acid sequences of the 
receptors are very similar and are believed to adopt a common structural 
framework comprising 7 transmembrane (TM) helices [3-5]. 
 
The muscarinic acetylcholine receptors, present in the central nervous
system, spinal cord motoneurons and autonomic preganglia, modulate a
variety of physiological functions: these include airway, eye and intestinal
smooth muscle contractions; heart rate; and glandular secretions. The
receptors mediate adenylate cyclase attenuation, calcium and potassium
channel activation, and phosphatidyl inositol turnover [6]. This diversity
may result from the occurrence of multiple receptor subtypes, which have
been classified based on observed differences in ligand binding to
receptors in membranes from several tissues.
 
MUSCARINICR is a 9-element fingerprint that provides a signature for the
muscarinic receptors. The fingerprint was derived from an initial alignment
of 11 sequences: the motifs were drawn from conserved sections within either
loop or TM regions, focusing on those areas of the alignment that
characterise the muscarinic receptors but distinguish them from the rest
of the rhodopsin-like superfamily - motif 1 lies in the N-terminal portion
of TM domain 1; motif 2 spans the C-terminus of TM domain 1 and part of the
first cytoplasmic loop; motif 3 lies at the C-terminus of TM domain 2;
motif 4 lies at the N-terminus of TM domain 3; motif 5 spans the second
cytoplasmic loop; motif 6 spans the C-terminus of TM domain 4 and part of
the second external loop; motif 7 spans part of the second external loop
leading into TM domain 5; motif 8 spans the third external loop; and motif
9 spans the C-terminus of TM domain 7 leading into the C-terminus. Two
iterations on OWL23.2 were required to reach convergence, at which point
a true set comprising 23 sequences was identfied. Several partial matches
were also found, all of which are members of the superfamily.
 
An update on SPTR37_9f identified a true set of 23 sequences, and 2
partial matches.
Summary Information
  23 codes involving  9 elements
0 codes involving 8 elements
0 codes involving 7 elements
0 codes involving 6 elements
0 codes involving 5 elements
0 codes involving 4 elements
0 codes involving 3 elements
1 codes involving 2 elements
Composite Feature Index
9232323232323232323
8000000000
7000000000
6000000000
5000000000
4000000000
3000000000
2000010001
123456789
True Positives
ACM1_DROME    ACM1_HUMAN    ACM1_MACMU    ACM1_MOUSE    
ACM1_PIG ACM1_RAT ACM2_CHICK ACM2_HUMAN
ACM2_PIG ACM2_RAT ACM3_BOVIN ACM3_CHICK
ACM3_HUMAN ACM3_PIG ACM3_RAT ACM4_CHICK
ACM4_HUMAN ACM4_MOUSE ACM4_RAT ACM4_XENLA
ACM5_HUMAN ACM5_MACMU ACM5_RAT
True Positive Partials
Codes involving 2 elements
O15970
Sequence Titles
ACM1_DROME  Muscarinic acetylcholine receptor DM1 - Drosophila melanogaster (Fruit fly). 
ACM1_HUMAN Muscarinic acetylcholine receptor M1 - Homo sapiens (Human).
ACM1_MACMU Muscarinic acetylcholine receptor M1 - Macaca mulatta (Rhesus macaque).
ACM1_MOUSE Muscarinic acetylcholine receptor M1 - Mus musculus (Mouse).
ACM1_PIG Muscarinic acetylcholine receptor M1 - Sus scrofa (Pig).
ACM1_RAT Muscarinic acetylcholine receptor M1 - Rattus norvegicus (Rat).
ACM2_CHICK Muscarinic acetylcholine receptor M2 - Gallus gallus (Chicken).
ACM2_HUMAN Muscarinic acetylcholine receptor M2 - Homo sapiens (Human).
ACM2_PIG Muscarinic acetylcholine receptor M2 - Sus scrofa (Pig).
ACM2_RAT Muscarinic acetylcholine receptor M2 - Rattus norvegicus (Rat).
ACM3_BOVIN Muscarinic acetylcholine receptor M3 - Bos taurus (Bovine).
ACM3_CHICK Muscarinic acetylcholine receptor M3 - Gallus gallus (Chicken).
ACM3_HUMAN Muscarinic acetylcholine receptor M3 - Homo sapiens (Human).
ACM3_PIG Muscarinic acetylcholine receptor M3 - Sus scrofa (Pig).
ACM3_RAT Muscarinic acetylcholine receptor M3 - Rattus norvegicus (Rat).
ACM4_CHICK Muscarinic acetylcholine receptor M4 - Gallus gallus (Chicken).
ACM4_HUMAN Muscarinic acetylcholine receptor M4 - Homo sapiens (Human).
ACM4_MOUSE Muscarinic acetylcholine receptor M4 (Mm4 mAChR) - Mus musculus (Mouse).
ACM4_RAT Muscarinic acetylcholine receptor M4 - Rattus norvegicus (Rat).
ACM4_XENLA Muscarinic acetylcholine receptor M4 - Xenopus laevis (African clawed frog).
ACM5_HUMAN Muscarinic acetylcholine receptor M5 - Homo sapiens (Human).
ACM5_MACMU Muscarinic acetylcholine receptor M5 - Macaca mulatta (Rhesus macaque).
ACM5_RAT Muscarinic acetylcholine receptor M5 - Rattus norvegicus (Rat).

O15970 SEROTONIN RECEPTOR-LIKE PLANARIAN RECEPTOR 1 - DUGESIA JAPONICA (PLANARIAN).
Scan History
OWL23_2    2  50   NSINGLE    
OWL28_0 1 70 NSINGLE
SPTR37_9f 2 30 NSINGLE
Initial Motifs
Motif 1  width=13
Element Seqn Id St Int Rpt
FIATVTGSLSLVT ACM4_MOUSE 33 33 -
FIAFLTGILALVT ACM3_PIG 70 70 -
FIVLVAGSLSLVT ACM2_CHICK 28 28 -
TIAVVTAVVSLMT ACM5_RAT 31 31 -
FIVLVAGSLSLVT ACM2_HUMAN 25 25 -
VMGFVAAILSTVT DROMACE 106 106 -
TIAVVTAVVSLIT ACM5_HUMAN 32 32 -
FIGITTGLLSLAT ACM1_PIG 27 27 -
FIGITTGLLSLAT ACM1_HUMAN 27 27 -
FIAFLTGILALVT ACM3_HUMAN 70 70 -
FIATVTGSLSLVT ACM4_CHICK 44 44 -

Motif 2 width=9
Element Seqn Id St Int Rpt
VSIKVNRHL ACM2_CHICK 49 8 -
ISFKIDKQL DROMACE 127 8 -
VSFKVNKQL ACM3_HUMAN 91 8 -
LSIKVNRQL ACM4_CHICK 65 8 -
LSIKVNRQL ACM4_MOUSE 54 8 -
VAFKVNKQL ACM3_PIG 91 8 -
ISFKVNTEL ACM1_HUMAN 48 8 -
ISFKVNTEL ACM1_PIG 48 8 -
ISFKVNSQL ACM5_HUMAN 53 8 -
ISFKVNSQL ACM5_RAT 52 8 -
VSIKVNRHL ACM2_HUMAN 46 8 -

Motif 3 width=11
Element Seqn Id St Int Rpt
GIFSMNLYTLY ACM2_CHICK 76 18 -
GVISMNLFTTY ACM3_HUMAN 118 18 -
GVFSMNLYTVY ACM4_CHICK 92 18 -
GAFSMNLYTLY ACM4_MOUSE 81 18 -
GVISMNLFTTY ACM3_PIG 118 18 -
GTFSMNLYTTY ACM1_HUMAN 75 18 -
GTFSMNLYTTY ACM1_PIG 75 18 -
GAISMPLFAVT DROMACE 154 18 -
GIFSMNLYTTY ACM5_HUMAN 80 18 -
GIFSMNLYTTY ACM5_RAT 79 18 -
GVFSMNLYTLY ACM2_HUMAN 73 18 -

Motif 4 width=10
Element Seqn Id St Int Rpt
YLASNASVLN DROMACE 185 20 -
YVASNASVMN ACM3_HUMAN 149 20 -
YVVSNASVMN ACM4_CHICK 123 20 -
YVVSNASVMN ACM4_MOUSE 112 20 -
YVASNASVMN ACM3_PIG 149 20 -
YVASNASVMN ACM1_PIG 106 20 -
YVASNASVMN ACM1_HUMAN 106 20 -
YVASNASVMN ACM5_HUMAN 111 20 -
YVASNASVMN ACM5_RAT 110 20 -
YVVSNASVMN ACM2_CHICK 107 20 -
YVVSNASVMN ACM2_HUMAN 104 20 -

Motif 5 width=15
Element Seqn Id St Int Rpt
FSITRPLTYRAKRTT ACM3_HUMAN 168 9 -
FSVTRPLTYRAKRTT DROMACE 204 9 -
FCVTKPLTYPARRTT ACM4_CHICK 142 9 -
FCVTKPLTYPARRTT ACM4_MOUSE 131 9 -
FSITRPLTYRAKRTT ACM3_PIG 168 9 -
FSVTRPLSYRAKRTP ACM1_HUMAN 125 9 -
FSVTRPLSYRAKRTP ACM1_PIG 125 9 -
FSITRPLTYRAKRTP ACM5_HUMAN 130 9 -
FSITRPLTYRAKRTP ACM5_RAT 129 9 -
FCVTKPLTYPVKRTT ACM2_CHICK 126 9 -
FCVTKPLTYPVKRTT ACM2_HUMAN 123 9 -

Motif 6 width=11
Element Seqn Id St Int Rpt
LCWQYLVGKRT ACM5_RAT 166 22 -
YSWPYIEGKRT DROMACE 241 22 -
LFWQFIVGVRT ACM2_HUMAN 160 22 -
LFWQFIVGGRT ACM2_CHICK 163 22 -
LFWQYFVGKRT ACM3_HUMAN 205 22 -
LFWQFIVGKRT ACM4_CHICK 179 22 -
LFWQFVVGKRT ACM4_MOUSE 168 22 -
LFWQYFVGKRT ACM3_PIG 205 22 -
LFWQYLVGERT ACM1_HUMAN 162 22 -
LFWQYLVGERT ACM1_PIG 162 22 -
LCWQYLVGKRT ACM5_HUMAN 167 22 -

Motif 7 width=12
Element Seqn Id St Int Rpt
FLSEPTITFGTA ACM3_PIG 225 9 -
FLSEPTITFGTA ACM3_HUMAN 225 9 -
FLSNPAVTFGTA ACM4_CHICK 199 9 -
FLSNPAVTFGTA ACM4_MOUSE 188 9 -
FLSQPIITFGTA ACM1_HUMAN 182 9 -
FLSQPIITFGTA ACM1_PIG 182 9 -
FLSEPTITFGTA ACM5_HUMAN 187 9 -
FLSEPTITFGTA ACM5_RAT 186 9 -
FFSNPAVTFGTA ACM2_CHICK 183 9 -
FFSNAAVTFGTA ACM2_HUMAN 180 9 -
IETNQYITFGTA DROMACE 262 10 -

Motif 8 width=19
Element Seqn Id St Int Rpt
FCAPCIPNTVWTIGYWLCY ACM2_HUMAN 412 220 -
FCDSCIPKTFWNLGYWLCY ACM3_HUMAN 516 279 -
FCETCVPETVWSIGYWLCY ACM4_CHICK 436 225 -
FCQSCIPERVWSIGYWLCY ACM4_MOUSE 425 225 -
FCDSCIPKTYWNLGYWLCY ACM3_PIG 516 279 -
TCSDCIPTELWDFFYALCY DROMACE 727 453 -
FCKDCVPETLWELGYWLCY ACM1_HUMAN 390 196 -
FCKDCVPETLWELGYWLCY ACM1_PIG 390 196 -
FCDKCVPVTLWHLGYWLCY ACM5_HUMAN 467 268 -
FCDKCVPVTLWHLGYWLCY ACM5_RAT 466 268 -
FCASCIPGTVWTIGYWLCY ACM2_CHICK 412 217 -

Motif 9 width=15
Element Seqn Id St Int Rpt
CNATFKKTFRHLLLC ACM4_MOUSE 456 12 -
CNKAFRDTFRLLLLC ACM1_HUMAN 421 12 -
CNATFKKTFKHLLMC ACM2_HUMAN 443 12 -
CNATFKKTFKHLLMC ACM2_CHICK 443 12 -
CNKTFRTTFKMLLLC ACM3_HUMAN 547 12 -
CNATFRRTYVRILTC DROMACE 758 12 -
CNRTFRKTFKMLLLC ACM5_HUMAN 498 12 -
CNKAFRDTFRLLLLC ACM1_PIG 421 12 -
CNRTFRKTFKLLLLC ACM5_RAT 497 12 -
CNATFKKTFKHLLMC ACM4_CHICK 467 12 -
CNKTFRTTFKMLLLC ACM3_PIG 547 12 -
Final Motifs
Motif 1  width=13
Element Seqn Id St Int Rpt
FIAFLTGILALVT ACM3_HUMAN 70 70 -
FIATVTGSLSLVT ACM4_CHICK 44 44 -
FIATVTGSLSLVT ACM4_HUMAN 34 34 -
FIATVTGSLSLVT ACM4_MOUSE 33 33 -
FIATVTGSLSLVT ACM4_RAT 33 33 -
FIAFLTGILALVT ACM3_PIG 70 70 -
FIAFLTGVLALVT ACM3_BOVIN 70 70 -
FIGITTGLLSLAT ACM1_HUMAN 27 27 -
FIGITTGLLSLAT ACM1_MACMU 27 27 -
FIGITTGLLSLAT ACM1_PIG 27 27 -
FIGITTGLLSLAT ACM1_RAT 27 27 -
FIAFLTGFLALVT ACM3_RAT 69 69 -
FIATVTGSLSLVT ACM4_XENLA 35 35 -
TIAVVTAVVSLIT ACM5_HUMAN 32 32 -
SIAAVTAVVSLIT ACM5_MACMU 32 32 -
FIGSTTGLLSLAT ACM1_MOUSE 27 27 -
TIAVVTAVVSLMT ACM5_RAT 31 31 -
FIVLVAGSLSLVT ACM2_CHICK 28 28 -
FIVLVAGSLSLVT ACM2_PIG 25 25 -
FIVLVAGSLSLVT ACM2_HUMAN 25 25 -
LIAFLTGIIALVT ACM3_CHICK 118 118 -
FIVLVAGSLSLVT ACM2_RAT 25 25 -
VMGFVAAILSTVT ACM1_DROME 26 26 -

Motif 2 width=9
Element Seqn Id St Int Rpt
VSFKVNKQL ACM3_HUMAN 91 8 -
LSIKVNRQL ACM4_CHICK 65 8 -
LSIKVNRQL ACM4_HUMAN 55 8 -
LSIKVNRQL ACM4_MOUSE 54 8 -
LSIKVNRQL ACM4_RAT 54 8 -
VAFKVNKQL ACM3_PIG 91 8 -
VAFKVNKQL ACM3_BOVIN 91 8 -
ISFKVNTEL ACM1_HUMAN 48 8 -
ISFKVNTEL ACM1_MACMU 48 8 -
ISFKVNTEL ACM1_PIG 48 8 -
ISFKVNTEL ACM1_RAT 48 8 -
VAFKVNKQL ACM3_RAT 90 8 -
LSIKVNRQL ACM4_XENLA 56 8 -
ISFKVNSQL ACM5_HUMAN 53 8 -
ISFKVNSQL ACM5_MACMU 53 8 -
ISIKVNTEL ACM1_MOUSE 48 8 -
ISFKVNSQL ACM5_RAT 52 8 -
VSIKVNRHL ACM2_CHICK 49 8 -
VSIKVNRHL ACM2_PIG 46 8 -
VSIKVNRHL ACM2_HUMAN 46 8 -
VSFKVNKQL ACM3_CHICK 139 8 -
VSIKVSRHL ACM2_RAT 46 8 -
ISFKIDKQL ACM1_DROME 47 8 -

Motif 3 width=11
Element Seqn Id St Int Rpt
GVISMNLFTTY ACM3_HUMAN 118 18 -
GVFSMNLYTVY ACM4_CHICK 92 18 -
GAFSMNLYTVY ACM4_HUMAN 82 18 -
GAFSMNLYTLY ACM4_MOUSE 81 18 -
GAFSMNLYTLY ACM4_RAT 81 18 -
GVISMNLFTTY ACM3_PIG 118 18 -
GVISMNLFTTY ACM3_BOVIN 118 18 -
GTFSMNLYTTY ACM1_HUMAN 75 18 -
GTFSMNLYTTY ACM1_MACMU 75 18 -
GTFSMNLYTTY ACM1_PIG 75 18 -
GTFSMNLYTTY ACM1_RAT 75 18 -
GVISMNLFTTY ACM3_RAT 117 18 -
GVFSMNLYSLY ACM4_XENLA 83 18 -
GIFSMNLYTTY ACM5_HUMAN 80 18 -
GIFSMNLYTTY ACM5_MACMU 80 18 -
GTFSMNLYTTY ACM1_MOUSE 75 18 -
GIFSMNLYTTY ACM5_RAT 79 18 -
GIFSMNLYTLY ACM2_CHICK 76 18 -
GVFSMNLYTLY ACM2_PIG 73 18 -
GVFSMNLYTLY ACM2_HUMAN 73 18 -
GVISMNLFTTY ACM3_CHICK 166 18 -
GVFSMNLYTLY ACM2_RAT 73 18 -
GTISMPLFAVT ACM1_DROME 74 18 -

Motif 4 width=10
Element Seqn Id St Int Rpt
YVASNASVMN ACM3_HUMAN 149 20 -
YVVSNASVMN ACM4_CHICK 123 20 -
YVVSNASVMN ACM4_HUMAN 113 20 -
YVVSNASVMN ACM4_MOUSE 112 20 -
YVVSNASVMN ACM4_RAT 112 20 -
YVASNASVMN ACM3_PIG 149 20 -
YVASNASVMN ACM3_BOVIN 149 20 -
YVASNASVMN ACM1_HUMAN 106 20 -
YVASNASVMN ACM1_MACMU 106 20 -
YVASNASVMN ACM1_PIG 106 20 -
YVASNASVMN ACM1_RAT 106 20 -
YVASNASVMN ACM3_RAT 148 20 -
YVVSNASVMN ACM4_XENLA 114 20 -
YVASNASVMN ACM5_HUMAN 111 20 -
YVASNASVMN ACM5_MACMU 111 20 -
YVASNASVMN ACM1_MOUSE 106 20 -
YVASNASVMN ACM5_RAT 110 20 -
YVVSNASVMN ACM2_CHICK 107 20 -
YVVSNASVMN ACM2_PIG 104 20 -
YVVSNASVMN ACM2_HUMAN 104 20 -
YVASNASVMN ACM3_CHICK 197 20 -
YVVSNASVMN ACM2_RAT 104 20 -
YLASNASVLN ACM1_DROME 105 20 -

Motif 5 width=15
Element Seqn Id St Int Rpt
FSITRPLTYRAKRTT ACM3_HUMAN 168 9 -
FCVTKPLTYPARRTT ACM4_CHICK 142 9 -
FCVTKPLTYPARRTT ACM4_HUMAN 132 9 -
FCVTKPLTYPARRTT ACM4_MOUSE 131 9 -
FCVTKPLTYPARRTT ACM4_RAT 131 9 -
FSITRPLTYRAKRTT ACM3_PIG 168 9 -
FSITRPLTYRAKRTT ACM3_BOVIN 168 9 -
FSVTRPLSYRAKRTP ACM1_HUMAN 125 9 -
FSVTRPLSYRAKRTP ACM1_MACMU 125 9 -
FSVTRPLSYRAKRTP ACM1_PIG 125 9 -
FSVTRPLSYRAKRTP ACM1_RAT 125 9 -
FSITRPLTYRAKRTT ACM3_RAT 167 9 -
FCVTKPLTYPARRTT ACM4_XENLA 133 9 -
FSITRPLTYRAKRTP ACM5_HUMAN 130 9 -
FSITRPLTYRAKRTP ACM5_MACMU 130 9 -
FSVTRPLSYRAKRTP ACM1_MOUSE 125 9 -
FSITRPLTYRAKRTP ACM5_RAT 129 9 -
FCVTKPLTYPVKRTT ACM2_CHICK 126 9 -
FCVTKPLTYPVKRTT ACM2_PIG 123 9 -
FCVTKPLTYPVKRTT ACM2_HUMAN 123 9 -
FSITRPLTYRAKRTT ACM3_CHICK 216 9 -
FCVTKPLTYPVKRTT ACM2_RAT 123 9 -
FSVTRPLTYRAKGTT ACM1_DROME 124 9 -

Motif 6 width=11
Element Seqn Id St Int Rpt
LFWQYFVGKRT ACM3_HUMAN 205 22 -
LFWQFIVGKRT ACM4_CHICK 179 22 -
LFWQFVVGKRT ACM4_HUMAN 169 22 -
LFWQFVVGKRT ACM4_MOUSE 168 22 -
LFWQFVVGKRT ACM4_RAT 168 22 -
LFWQYFVGKRT ACM3_PIG 205 22 -
LFWQYFVGKRT ACM3_BOVIN 205 22 -
LFWQYLVGERT ACM1_HUMAN 162 22 -
LFWQYLVGERT ACM1_MACMU 162 22 -
LFWQYLVGERT ACM1_PIG 162 22 -
LFWQYLVGERT ACM1_RAT 162 22 -
LFWQYFVGKRT ACM3_RAT 204 22 -
LFWQFIVGQRT ACM4_XENLA 170 22 -
LCWQYLVGKRT ACM5_HUMAN 167 22 -
LCWQYLVGKRT ACM5_MACMU 167 22 -
LFWQYLVGERT ACM1_MOUSE 162 22 -
LCWQYLVGKRT ACM5_RAT 166 22 -
LFWQFIVGGRT ACM2_CHICK 163 22 -
LFWQFIVGVRT ACM2_PIG 160 22 -
LFWQFIVGVRT ACM2_HUMAN 160 22 -
LFWQYFVGKRT ACM3_CHICK 253 22 -
LFWQFIVGVRT ACM2_RAT 160 22 -
YSWPYIEGKRT ACM1_DROME 160 21 -

Motif 7 width=12
Element Seqn Id St Int Rpt
FLSEPTITFGTA ACM3_HUMAN 225 9 -
FLSNPAVTFGTA ACM4_CHICK 199 9 -
FLSNPAVTFGTA ACM4_HUMAN 189 9 -
FLSNPAVTFGTA ACM4_MOUSE 188 9 -
FLSNPAVTFGTA ACM4_RAT 188 9 -
FLSEPTITFGTA ACM3_PIG 225 9 -
FLSEPTITFGTA ACM3_BOVIN 225 9 -
FLSQPIITFGTA ACM1_HUMAN 182 9 -
FLSQPIITFGTA ACM1_MACMU 182 9 -
FLSQPIITFGTA ACM1_PIG 182 9 -
FLSQPIITFGTA ACM1_RAT 182 9 -
FLSEPTITFGTA ACM3_RAT 224 9 -
FLSNPAVTFGTA ACM4_XENLA 190 9 -
FLSEPTITFGTA ACM5_HUMAN 187 9 -
FLSEPTITFGTA ACM5_MACMU 187 9 -
FLSQPIITFGTA ACM1_MOUSE 182 9 -
FLSEPTITFGTA ACM5_RAT 186 9 -
FFSNPAVTFGTA ACM2_CHICK 183 9 -
FFSNAAVTFGTA ACM2_PIG 180 9 -
FFSNAAVTFGTA ACM2_HUMAN 180 9 -
FLSEPIITFGTA ACM3_CHICK 273 9 -
FFSNAAVTFGTA ACM2_RAT 180 9 -
IETNQYITFGTA ACM1_DROME 181 10 -

Motif 8 width=19
Element Seqn Id St Int Rpt
FCDSCIPKTFWNLGYWLCY ACM3_HUMAN 516 279 -
FCETCVPETVWSIGYWLCY ACM4_CHICK 436 225 -
FCQSCIPDTVWSIGYWLCY ACM4_HUMAN 425 224 -
FCQSCIPERVWSIGYWLCY ACM4_MOUSE 425 225 -
FCQSCIPERVWSIGYWLCY ACM4_RAT 424 224 -
FCDSCIPKTYWNLGYWLCY ACM3_PIG 516 279 -
FCDSCIPKTYWNLGYWLCY ACM3_BOVIN 516 279 -
FCKDCVPETLWELGYWLCY ACM1_HUMAN 390 196 -
FCKDCVPETLWELGYWLCY ACM1_MACMU 390 196 -
FCKDCVPETLWELGYWLCY ACM1_PIG 390 196 -
FCKDCVPETLWELGYWLCY ACM1_RAT 390 196 -
FCDSCIPKTYWNLGYWLCY ACM3_RAT 515 279 -
FCQTCIPETIWYIGYWLCY ACM4_XENLA 430 228 -
FCDKCVPVTLWHLGYWLCY ACM5_HUMAN 467 268 -
FCDKCVPVTLWHLGYWLCY ACM5_MACMU 467 268 -
FCKDCVPETLWELGYWLCY ACM1_MOUSE 390 196 -
FCDKCVPVTLWHLGYWLCY ACM5_RAT 466 268 -
FCASCIPGTVWTIGYWLCY ACM2_CHICK 412 217 -
FCAPCIPNTVWTIGYWLCY ACM2_PIG 412 220 -
FCAPCIPNTVWTIGYWLCY ACM2_HUMAN 412 220 -
TFCDCVPKTVWNLGYWLCY ACM3_CHICK 565 280 -
FCAPCIPNTVWTIGYWLCY ACM2_RAT 412 220 -
TCSDCIPTELWDFFYALCY ACM1_DROME 661 468 -

Motif 9 width=15
Element Seqn Id St Int Rpt
CNKTFRTTFKMLLLC ACM3_HUMAN 547 12 -
CNATFKKTFKHLLMC ACM4_CHICK 467 12 -
CNATFKKTFRHLLLC ACM4_HUMAN 456 12 -
CNATFKKTFRHLLLC ACM4_MOUSE 456 12 -
CNATFKKTFRHLLLC ACM4_RAT 455 12 -
CNKTFRTTFKMLLLC ACM3_PIG 547 12 -
CNKTFRNTFKMLLLC ACM3_BOVIN 547 12 -
CNKAFRDTFRLLLLC ACM1_HUMAN 421 12 -
CNKAFRDTFRLLLLC ACM1_MACMU 421 12 -
CNKAFRDTFRLLLLC ACM1_PIG 421 12 -
CNKAFRDTFRLLLLC ACM1_RAT 421 12 -
CNKTFRTTFKTLLLC ACM3_RAT 546 12 -
CNATFKKTFKHLLMC ACM4_XENLA 461 12 -
CNRTFRKTFKMLLLC ACM5_HUMAN 498 12 -
CNRTFRKTFKMLLLC ACM5_MACMU 498 12 -
CNKAFRDHFRLLLLC ACM1_MOUSE 421 12 -
CNRTFRKTFKLLLLC ACM5_RAT 497 12 -
CNATFKKTFKHLLMC ACM2_CHICK 443 12 -
CNATFKKTFKHLLMC ACM2_PIG 443 12 -
CNATFKKTFKHLLMC ACM2_HUMAN 443 12 -
CNKMFRNTFKMLLLC ACM3_CHICK 596 12 -
CNATFKKTFKHLLMC ACM2_RAT 443 12 -
CNATFRRTYVRILTC ACM1_DROME 692 12 -