| Literature References | 1. NUIJTEN, P.J.M., VAN ASTEN, F.J.A.M., GAASTRA, W. AND
VAN DER ZEIJST, B.A.M.
Structural and functional analyis of 2 Campylobacter jejuni flagellin genes.
J.BIOL.CHEM. 265(29) 17798-17804 (1990).
2. LAVALLIE, E.R. AND STAHL, M.L.
Cloning of the flagellin gene from Bacillus subtilus and complementation
studies of an in vitro derived deletion mutant.
J.BACTERIOL. 171(6) 3085-3094 (1989).
3. KUWAJIMA, G., ASAKA, J.I., FUJIWARA, T., NODE, K. AND KONDO, E.
Nucleotide sequence of the hag gene encoding flagellin of Escherichia coli.
J.BACTERIOL. 168(3) 1479-1483 (1986).
|
| Documentation | Bacterial flagella are responsible for motility and chemotaxis [1]. They
comprise a basal body, a hook and a filament, the latter accounting for 98%
of the mass [2]. Flagellin is the subunit protein that polymerises to form
the flagellae [3], the subunits being transported through the centre of the
filament to the tip, where they then polymerize [1]. Both the N- and C-
termini of the subunit protein, which are alpha-helical in structure [1],
are required to mediate polymerisation. Although no export or assembly
consensus sequences have been identified, Ala, Val, Leu, Ile, Gly, Ser,
Thr, Asn, Gln and Asp tend to make up around 90% of the sequence, Cys and
Trp being absent [2].
FLAGELLIN is a 3-element fingerprint that provides a signature for the
bacterial flagellins. The fingerprint was derived from an initial alignment
of 4 sequences: the motifs were drawn from well-conserved N-terminal
regions. Five iterations on OWL21.1 were required to reach convergence, at
which point a true set comprising 64 sequences was identified. Five partial
matches were also found, most of which are flagellins that fail to make a
significant match with motif 2.
An update on SPTR37_9f identified a true set of 148 sequences, and 11
partial matches.
|
| Sequence Titles | FLA1_BORBU FLAGELLAR FILAMENT 41 KD CORE PROTEIN (FLAGELLIN) (P41) (41 KD ANTIGEN) - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
FLA1_TREPA FLAGELLAR FILAMENT 34.5 KD CORE PROTEIN (CLASS B) - TREPONEMA PALLIDUM.
FLA2_TREPA FLAGELLAR FILAMENT 33 KD CORE PROTEIN (CLASS B) - TREPONEMA PALLIDUM.
FLA2_TREPH FLAGELLAR FILAMENT 33 KD CORE PROTEIN (CLASS B) - TREPONEMA PHAGEDENIS.
FLA3_TREPA FLAGELLAR FILAMENT 31 KD CORE PROTEIN (CLASS B) - TREPONEMA PALLIDUM.
FLAA_AQUPY FLAGELLIN - AQUIFEX PYROPHILUS.
FLAA_BORBR FLAGELLIN - BORDETELLA BRONCHISEPTICA.
FLAA_CAMCO FLAGELLIN A - CAMPYLOBACTER COLI.
FLAA_CAMJE FLAGELLIN A - CAMPYLOBACTER JEJUNI.
FLAA_HELMU FLAGELLIN A - HELICOBACTER MUSTELAE.
FLAA_HELPY FLAGELLIN A - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).
FLAA_LISMO FLAGELLIN - LISTERIA MONOCYTOGENES.
FLAA_PSEAE FLAGELLIN - PSEUDOMONAS AERUGINOSA.
FLAA_VIBPA LATERAL FLAGELLIN - VIBRIO PARAHAEMOLYTICUS.
FLAB_CAMCO FLAGELLIN B (FLAGELLIN N) - CAMPYLOBACTER COLI.
FLAB_CAMJE FLAGELLIN B - CAMPYLOBACTER JEJUNI.
FLAB_HELMU FLAGELLIN B (FLAGELLIN N) - HELICOBACTER MUSTELAE.
FLAB_HELPY FLAGELLIN B (FLAGELLIN N) - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).
FLA_BACS5 FLAGELLIN - BACILLUS HALODURANS (BACILLUS SP. (STRAIN C-125)).
FLA_BACSU FLAGELLIN - BACILLUS SUBTILIS.
FLA_LEGMI FLAGELLIN - LEGIONELLA MICDADEI.
FLB2_TREHY FLAGELLAR FILAMENT CORE PROTEIN FLAB2 (34 KD CORE PROTEIN) - TREPONEMA HYODYSENTERIAE (SERPULINA HYODYSENTERIAE).
FLC1_PROMI FLAGELLIN 1 - PROTEUS MIRABILIS.
FLC2_PROMI FLAGELLIN 2 - PROTEUS MIRABILIS.
FLIC_ECOLI FLAGELLIN - ESCHERICHIA COLI.
FLIC_SALBE FLAGELLIN (PHASE-1-I FLAGELLIN) - SALMONELLA BERTA.
FLIC_SALBU FLAGELLIN (PHASE-1-C FLAGELLIN) - SALMONELLA BUDAPEST.
FLIC_SALCH FLAGELLIN (PHASE-1-C FLAGELLIN) - SALMONELLA CHOLERAE-SUIS (SALMONELLA ENTERICA).
FLIC_SALDE FLAGELLIN (PHASE-1-C FLAGELLIN) - SALMONELLA DERBY.
FLIC_SALDU FLAGELLIN (PHASE-1-C FLAGELLIN) - SALMONELLA DUBLIN.
FLIC_SALEN FLAGELLIN (PHASE-1-C FLAGELLIN) - SALMONELLA ENTERITIDIS.
FLIC_SALMC FLAGELLIN (PHASE-1-D FLAGELLIN) - SALMONELLA MOSCOW.
FLIC_SALMO FLAGELLIN (PHASE-1-C FLAGELLIN) - SALMONELLA MONTEVIDEO.
FLIC_SALMU FLAGELLIN (PHASE-1-D FLAGELLIN) - SALMONELLA MUENCHEN.
FLIC_SALON FLAGELLIN (PHASE-1-C FLAGELLIN) - SALMONELLA ORANIENBERG.
FLIC_SALPA FLAGELLIN (PHASE-1-A FLAGELLIN) - SALMONELLA PARATYPHI-A.
FLIC_SALRO FLAGELLIN (PHASE-1-C FLAGELLIN) - SALMONELLA ROSTOCK.
FLIC_SALRU FLAGELLIN (PHASE-1-R FLAGELLIN) - SALMONELLA RUBISLAW.
FLIC_SALSE FLAGELLIN (PHASE-1-C FLAGELLIN) - SALMONELLA SENFTENBERG.
FLIC_SALTY FLAGELLIN (PHASE-1-I FLAGELLIN) - SALMONELLA TYPHIMURIUM.
FLIC_SERMA FLAGELLIN - SERRATIA MARCESCENS.
FLIC_SHIFL FLAGELLIN - SHIGELLA FLEXNERI.
FLJB_SALAE PHASE-2 FLAGELLIN - SALMONELLA ABORTUS-EQUI.
FLJB_SALTY PHASE-2 FLAGELLIN - SALMONELLA TYPHIMURIUM.
O30376 FLAGELLIN PROTEIN - AEROMONAS SALMONICIDA.
O30377 FLAGELLIN PROTEIN - AEROMONAS SALMONICIDA.
O30858 FLAGELLIN CORE PROTEIN A - VIBRIO CHOLERAE.
O31059 FLAA - BUTYRIVIBRIO FIBRISOLVENS.
O31062 FLAB - BUTYRIVIBRIO FIBRISOLVENS.
O33578 FLAGELLAR FILAMENT PROTEIN - RHODOBACTER SPHAEROIDES (RHODOPSEUDOMONAS SPHAEROIDES).
O34220 FLAGELLIN - VIBRIO CHOLERAE.
O34221 FLAGELLIN - VIBRIO CHOLERAE.
O34223 FLAGELLIN - VIBRIO CHOLERAE.
O51941 PERIPLASMIC FLAGELLIN - LEPTOSPIRA INTERROGANS.
O52529 FLJM FLAGELLIN - CAULOBACTER CRESCENTUS.
O52530 FLJN FLAGELLIN - CAULOBACTER CRESCENTUS.
O52531 FLJO FLAGELLIN - CAULOBACTER CRESCENTUS.
O52959 PHASE-1 FLAGELLIN - SALMONELLA NAESTVED.
O67803 FLAGELLIN - AQUIFEX AEOLICUS.
O68143 TYPE II FLAGELLIN - BURKHOLDERIA CEPACIA (PSEUDOMONAS CEPACIA).
O68144 TYPE I FLAGELLIN - BURKHOLDERIA CEPACIA (PSEUDOMONAS CEPACIA).
O69136 FLAGELLIN - CLOSTRIDIUM ACETOBUTYLICUM.
O85179 FLAGELLIN A - CAMPYLOBACTER JEJUNI.
O85180 FLAGELLIN A - CAMPYLOBACTER JEJUNI.
O85181 FLAGELLIN B - CAMPYLOBACTER JEJUNI.
O85182 FLAGELLIN A - CAMPYLOBACTER JEJUNI.
O85183 FLAGELLIN A - CAMPYLOBACTER JEJUNI.
O85825 FLAGELLIN SUBUNIT - ESCHERICHIA COLI.
O86045 FLAGELLIN - BURKHOLDERIA THAILANDENSIS.
O86265 FLAGELLIN - PSEUDOMONAS AERUGINOSA.
O86266 FLAGELLIN - PSEUDOMONAS AERUGINOSA.
O87081 POLAR FLAGELLIN - VIBRIO PARAHAEMOLYTICUS.
P70944 FLAGELLIN - BURKHOLDERIA PSEUDOMALLAI (PSEUDOMONAS PSEUDOMALLAI).
P71246 FLAGELLIN - ESCHERICHIA COLI.
P72151 FLAGELLIN - PSEUDOMONAS AERUGINOSA.
P96747 FLAGELLIN - CAMPYLOBACTER JEJUNI.
P96752 FLAGELLIN - CAMPYLOBACTER SP.
Q01673 FLAGELLIN - CAMPYLOBACTER JEJUNI.
Q02871 FLAGELLIN (PHASE-1-I FLAGELLIN) - SALMONELLA TYPHIMURIUM.
Q03844 FLAGELLIN (FLAGELLIN A) - CAMPYLOBACTER JEJUNI.
Q06351 FLAGELLIN - ESCHERICHIA COLI.
Q06352 FLAGELLIN - ESCHERICHIA COLI.
Q06353 FLAGELLIN - ESCHERICHIA COLI.
Q09012 FLAGELLIN - SHIGELLA SONNEI.
Q26501 FLAGELLAR PROTEIN - TREPONEMA HYODYSENTERIAE (SERPULINA HYODYSENTERIAE).
Q43896 FLAGELLIN LAF1 - AZOSPIRILLUM BRASILENSE.
Q44649 FLAGELLIN - BORRELIA ANSERINA.
Q44650 FLAGELLIN - BORRELIA AFZELII.
Q44746 P41 GENE - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
Q44895 FLAGELLIN - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
Q44932 P41 GENE - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
Q45019 P41 PROTEIN - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
Q45027 P41 GENE - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
Q45042 P41 GENE - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
Q45080 FLAGELLIN - BORRELIA CROCIDURAE.
Q45102 FLAGELLIN - BORRELIA CROCIDURAE.
Q45204 FLAGELLIN - BORRELIA HERMSII.
Q45565 FLAGELLIN PROTEIN - BORRELIA MIYAMOTOI.
Q45761 FLAGELLIN - BACILLUS THURINGIENSIS.
Q45762 FLAGELLIN - BACILLUS THURINGIENSIS.
Q46009 FLAGELLIN - CAMPYLOBACTER COLI.
Q46113 FLAGELLIN A - CAMPYLOBACTER JEJUNI.
Q46114 FLAGELLIN B - CAMPYLOBACTER JEJUNI.
Q47226 FLAGELLIN - ESCHERICHIA COLI.
Q48824 FLAGELLIN - LEGIONELLA PNEUMOPHILA.
Q52079 FLAGELLIN - PSEUDOMONAS PUTIDA.
Q52080 FLAGELLIN - PSEUDOMONAS PUTIDA.
Q52694 FLAGELLIN - ROSEBURIA CECICOLA.
Q53789 FLAGELLIN - SHIGELLA BOYDII.
Q53834 PHASE-2 FLAGELLIN STRUCTURAL PROTEIN - SALMONELLA CHOLERAE-SUIS (SALMONELLA ENTERICA).
Q53835 PHASE-2 FLAGELLIN STRUCTURAL PROTEIN - SALMONELLA CHOLERAE-SUIS (SALMONELLA ENTERICA).
Q53836 PHASE-2 FLAGELLIN STRUCTURAL PROTEIN - SALMONELLA CHOLERAE-SUIS (SALMONELLA ENTERICA).
Q53837 PHASE-2 FLAGELLIN STRUCTURAL PROTEIN - SALMONELLA CHOLERAE-SUIS (SALMONELLA ENTERICA).
Q53969 FLAGELLIN - SHIGELLA DYSENTERIAE.
Q53970 PHASE-1 FLAGELLIN - SALMONELLA DUBLIN.
Q53990 PHASE 1 FLAGELLIN - SALMONELLA TYPHIMURIUM.
Q53991 PHASE 1 FLAGELLIN - SALMONELLA TYPHIMURIUM.
Q53992 PHASE 1 FLAGELLIN - SALMONELLA TYPHIMURIUM.
Q53993 PHASE 1 FLAGELLIN - SALMONELLA TYPHIMURIUM.
Q53994 PHASE 1 FLAGELLIN - SALMONELLA TYPHIMURIUM.
Q53995 PHASE 1 FLAGELLIN - SALMONELLA TYPHIMURIUM.
Q53996 PHASE 1 FLAGELLIN - SALMONELLA TYPHIMURIUM.
Q54210 PHASE-1 FLAGELLIN - SALMONELLA GALLINARUM.
Q54444 FLAGELLIN - SERRATIA MARCESCENS.
Q54489 PHASE 1 FLAGELLIN - SALMONELLA NEWMEXICO.
Q54515 PHASE 1 FLAGELLIN - SALMONELLA PENSACOLA.
Q54863 PHASE-1 FLAGELLIN - SALMONELLA PULLORUM.
Q54864 PHASE-1 FLAGELLIN - SALMONELLA PULLORUM.
Q56086 FLAGELLIN - SALMONELLA TYPHI.
Q56570 FLAGELLIN E - VIBRIO ANGUILLARUM.
Q56571 FLAGELLIN D - VIBRIO ANGUILLARUM.
Q56572 FLAGELLIN B - VIBRIO ANGUILLARUM.
Q56574 FLAGELLIN C - VIBRIO ANGUILLARUM.
Q56603 FLAGELLIN (ORF4) - VIBRIO CHOLERAE.
Q56609 FLAGELLIN (ORF5) - VIBRIO CHOLERAE.
Q56702 FLAB - VIBRIO PARAHAEMOLYTICUS.
Q56703 FLAA - VIBRIO PARAHAEMOLYTICUS.
Q56712 FLAC - VIBRIO PARAHAEMOLYTICUS.
Q56713 FLAD - VIBRIO PARAHAEMOLYTICUS.
Q56746 FLAGELLIN - WOLINELLA SUCCINOGENES.
Q56826 FLAGELLIN - XENORHABDUS NEMATOPHILUS.
Q56911 THERMOREGULATED MOTILITY PROTEIN - YERSINIA ENTEROCOLITICA.
Q56912 THERMOREGULATED MOTILITY PROTEIN - YERSINIA ENTEROCOLITICA.
Q57019 P41 P41 PROTEIN - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
Q57381 PHASE-1 FLAGELLIN - SALMONELLA ENTERITIDIS, AND SALMONELLA OTHMARSCHEN.
Q57406 FLAGELLIN - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
Q57436 FLAGELLIN - BORRELIA GARINII, AND BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
Q60246 FLAGELLIN A - VIBRIO ANGUILLARUM.
FLAA_RHIME FLAGELLIN - RHIZOBIUM MELILOTI.
FLAB_RHIME FLAGELLIN - RHIZOBIUM MELILOTI.
O34166 FLAD - AGROBACTERIUM TUMEFACIENS.
P96307 FLAA, FLAB & FLAC GENES - AGROBACTERIUM TUMEFACIENS.
P96308 FLAA, FLAB & FLAC GENES - AGROBACTERIUM TUMEFACIENS.
P96309 FLAA, FLAB & FLAC GENES - AGROBACTERIUM TUMEFACIENS.
Q03841 FLAGELLIN - RHIZOBIUM MELILOTI.
Q03842 FLAGELLIN - RHIZOBIUM MELILOTI.
Q52941 FLAB PROTEIN - RHIZOBIUM MELILOTI.
Q52942 FLAD PROTEIN - RHIZOBIUM MELILOTI.
Q52943 FLAC PROTEIN - RHIZOBIUM MELILOTI.
|