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PR00176

Identifier
NANEUSMPORT  [View Relations]  [View Alignment]  
Accession
PR00176
No. of Motifs
8
Creation Date
20-FEB-1994  (UPDATE 23-SEP-1999)
Title
Sodium/chloride neurotransmitter symporter signature
Database References
PRINTS; PR01203 5HTTRANSPORT; PR01198 BETTRANSPORT; PR01199 CRTTRANSPORT
PRINTS; PR01202 DOPTRANSPORT; PR01195 GAT1TRNSPORT; PR01196 GAT2TRNSPORT
PRINTS; PR01197 GAT3TRNSPORT; PR01204 GLY1TRNSPORT; PR01205 INEBRIATED
PRINTS; PR01201 NORTRANSPORT; PR01206 ORPHTRNSPORT; PR01200 TAUTRANSPORT

PROSITE; PS00610 NA_NEUROTRAN_SYMP_1; PS00754 NA_NEUROTRAN_SYMP_2
BLOCKS; BL00610
PFAM; PF00209 SNF
INTERPRO; IPR000175
Literature References
1. ATTELL, D. AND MOBBS, P.
Neurotransmitter transporters.
CURR.OPIN.NEUROBIOL. 4 353-359 (1994).
 
2. MALANDRO, M.S. AND KILBERG, M.S.
Molecular biology of mammalian amino acid transporters.
ANNU.REV.BIOCHEMISTRY 65 305-336 (1996).
 
3. AMARA, S.G. AND ARRIZA, J.L.
Neurotransmitter transporters: three distinct gene families.
CURR.OPIN.NEUROBIOL. 3 337-344 (1993).
 
4. UHL, G.R. AND JOHNSON, P.S.
Neurotransmitter transporters: Three important gene families for neuronal
function.
J.EXP.BIOL. 196 229-236 (1994).
 
5. LILL, H. AND NELSON, N.
Homologies and family relationships among Na+/Cl- neurotransmitter
transporters.
METHODS ENZYMOL. 306 425-436 (1998).

Documentation
Neurotransmitter transport systems are integral to the release, re-uptake
and recycling of neurotransmitters at synapses. High affinity tranport
proteins found in the plasma membrane of presynaptic nerve terminals and
glial cells are responsible for the removal from the extracellular space
of released-transmitters, thereby terminating their actions [1]. Plasma
membrane neurotransmitter transporters fall into two structurally and
mechanistically distinct families. The majority of the transporters
constitute an extensive family of homologous proteins that derive energy
from the co-transport of Na+ and Cl-, in order to transport neurotransmitter
molecules into the cell against their concentration gradient. The family 
has a common structure of 12 presumed transmembrane helices and includes 
carriers for gamma-aminobutyric acid (GABA), noradrenaline/adrenaline, 
dopamine, serotonin, proline, glycine, choline, betaine and taurine. They
are structurally distinct from the second more-restricted family of plasma
membrane transporters, which are responsible for excitatory amino acid
tranport. The latter couple glutamate and aspartate uptake to the co-
transport of Na+ and the counter-transport of K+, with no apparent
dependence on Cl- [2]. In addition, both of these transporter families
are distinct from the vesicular neurotransmitter transporters [3,4].
 
Sequence analysis of the Na+/Cl- neurotransmitter superfamily reveals that
it can be divided into four subfamilies, these being transporters for
monoamines, the amino acids proline and glycine, GABA, and a group of
orphan transporters [5].
 
NANEUSMPORT is an 8-element fingerprint that provides a signature for the
Na+/Cl- -coupled neurotransmitter transporter superfamily. The fingerprint
was derived from an initial alignment of 9 sequences: the motifs were drawn
from TM regions 1-3, 5, 7-8 and 10-11 respectively (the other TM regions
were not sufficiently well-conserved to be included in the fingerprint).
Two iterations on OWL22.1 were required to reach convergence, at which
point a true set comprising 33 sequences was identified. A single partial
match was also found, S28306, a hypothetical protein fragment from
C.elegans that is similar to 6 of the 8 motifs.
 
An update on SPTR37_9f identified a true set of 61 sequences, and 19
partial matches.
Summary Information
  61 codes involving  8 elements
2 codes involving 7 elements
2 codes involving 6 elements
3 codes involving 5 elements
2 codes involving 4 elements
4 codes involving 3 elements
6 codes involving 2 elements
Composite Feature Index
86161616161616161
722222121
622222110
522223211
422202000
343401000
251401100
12345678
True Positives
NTBE_CANFA    NTBE_HUMAN    NTBE_MOUSE    NTBE_RABIT    
NTBE_RAT NTCH_RAT NTCR_BOVIN NTCR_HUMAN
NTCR_RABIT NTDO_BOVIN NTDO_HUMAN NTDO_RAT
NTG1_HUMAN NTG1_MOUSE NTG1_MUSCO NTG1_RAT
NTG2_MOUSE NTG2_RAT NTG3_HUMAN NTG3_MOUSE
NTG3_RAT NTGL_BOVIN NTGL_HUMAN NTGL_MOUSE
NTGL_RAT NTNO_BOVIN NTNO_HUMAN NTNO_MOUSE
NTPR_RAT NTSE_CAVPO NTSE_DROME NTSE_HUMAN
NTSE_MOUSE NTSE_RAT NTT4_RAT NTT7_RAT
NTTA_CANFA NTTA_HUMAN NTTA_MOUSE NTTA_MUSCO
NTTA_RAT O02003 O17372 O42482
O73771 O76188 O88575 O88576
O88577 P90890 Q22116 Q23969
Q25512 Q62687 Q63380 Q64093
Q91494 Q91502 Q91503 Q94917
YN05_CAEEL
True Positive Partials
Codes involving 7 elements
O88578 O88579
Codes involving 6 elements
O45813 O88580
Codes involving 5 elements
O50649 O88581 Q13032
Codes involving 4 elements
O28284 YD19_METJA
Codes involving 3 elements
O34383 O50080 Y736_HAEIN YG90_HAEIN
Codes involving 2 elements
CINA_ELEEL O07577 O30781 O67854
O83067 O84234
Sequence Titles
NTBE_CANFA  SODIUM- AND CHLORIDE-DEPENDENT BETAINE TRANSPORTER (NA+/CL- BETAINE/GABA TRANSPORTER) - CANIS FAMILIARIS (DOG). 
NTBE_HUMAN SODIUM- AND CHLORIDE-DEPENDENT BETAINE TRANSPORTER (NA+/CL- BETAINE/GABA TRANSPORTER) (BGT-1) - HOMO SAPIENS (HUMAN).
NTBE_MOUSE SODIUM- AND CHLORIDE-DEPENDENT BETAINE TRANSPORTER (NA+/CL- BETAINE/GABA TRANSPORTER) (SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 4) (GAT2) - MUS MUSCULUS (MOUSE).
NTBE_RABIT SODIUM- AND CHLORIDE-DEPENDENT BETAINE TRANSPORTER (NA+/CL- BETAINE/GABA TRANSPORTER) - ORYCTOLAGUS CUNICULUS (RABBIT).
NTBE_RAT SODIUM- AND CHLORIDE-DEPENDENT BETAINE TRANSPORTER (NA+/CL- BETAINE/GABA TRANSPORTER) - RATTUS NORVEGICUS (RAT).
NTCH_RAT SODIUM-DEPENDENT CHOLINE TRANSPORTER (CHOT1) - RATTUS NORVEGICUS (RAT).
NTCR_BOVIN SODIUM- AND CHLORIDE-DEPENDENT CREATINE TRANSPORTER 1 (CT1) - BOS TAURUS (BOVINE).
NTCR_HUMAN SODIUM- AND CHLORIDE-DEPENDENT CREATINE TRANSPORTER 1 (CT1) - HOMO SAPIENS (HUMAN).
NTCR_RABIT SODIUM- AND CHLORIDE-DEPENDENT CREATINE TRANSPORTER 1 (CT1) - ORYCTOLAGUS CUNICULUS (RABBIT).
NTDO_BOVIN SODIUM-DEPENDENT DOPAMINE TRANSPORTER (DA TRANSPORTER) (DAT) - BOS TAURUS (BOVINE).
NTDO_HUMAN SODIUM-DEPENDENT DOPAMINE TRANSPORTER (DA TRANSPORTER) (DAT) - HOMO SAPIENS (HUMAN).
NTDO_RAT SODIUM-DEPENDENT DOPAMINE TRANSPORTER (DA TRANSPORTER) (DAT) - RATTUS NORVEGICUS (RAT).
NTG1_HUMAN SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 1 - HOMO SAPIENS (HUMAN).
NTG1_MOUSE SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 1 - MUS MUSCULUS (MOUSE).
NTG1_MUSCO SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 1 - MUS COOKII.
NTG1_RAT SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 1 - RATTUS NORVEGICUS (RAT).
NTG2_MOUSE SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 2 (GAT3) - MUS MUSCULUS (MOUSE).
NTG2_RAT SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 2 - RATTUS NORVEGICUS (RAT).
NTG3_HUMAN SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 3 - HOMO SAPIENS (HUMAN).
NTG3_MOUSE SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 3 (GAT4) - MUS MUSCULUS (MOUSE).
NTG3_RAT SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 3 - RATTUS NORVEGICUS (RAT).
NTGL_BOVIN SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 1 (GLYT-1) - BOS TAURUS (BOVINE).
NTGL_HUMAN SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 1 (GLYT-1) - HOMO SAPIENS (HUMAN).
NTGL_MOUSE SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 1 (GLYT-1) - MUS MUSCULUS (MOUSE).
NTGL_RAT SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 1 (GLYT-1) - RATTUS NORVEGICUS (RAT).
NTNO_BOVIN SODIUM-DEPENDENT NORADRENALINE TRANSPORTER (NOREPINEPHRINE TRANSPORTER) (NET) - BOS TAURUS (BOVINE).
NTNO_HUMAN SODIUM-DEPENDENT NORADRENALINE TRANSPORTER (NOREPINEPHRINE TRANSPORTER) (NET) - HOMO SAPIENS (HUMAN).
NTNO_MOUSE SODIUM-DEPENDENT NORADRENALINE TRANSPORTER (NOREPINEPHRINE TRANSPORTER) (NET) - MUS MUSCULUS (MOUSE).
NTPR_RAT SODIUM-DEPENDENT PROLINE TRANSPORTER - RATTUS NORVEGICUS (RAT).
NTSE_CAVPO SODIUM-DEPENDENT SEROTONIN TRANSPORTER (5HT TRANSPORTER) (5HTT) - CAVIA PORCELLUS (GUINEA PIG).
NTSE_DROME SODIUM-DEPENDENT SEROTONIN TRANSPORTER (5HT TRANSPORTER) (5HTT) (COCAINE-SENSITIVE SEROTONIN TRANSPORTER) - DROSOPHILA MELANOGASTER (FRUIT FLY).
NTSE_HUMAN SODIUM-DEPENDENT SEROTONIN TRANSPORTER (5HT TRANSPORTER) (5HTT) - HOMO SAPIENS (HUMAN).
NTSE_MOUSE SODIUM-DEPENDENT SEROTONIN TRANSPORTER (5HT TRANSPORTER) (5HTT) - MUS MUSCULUS (MOUSE).
NTSE_RAT SODIUM-DEPENDENT SEROTONIN TRANSPORTER (5HT TRANSPORTER) (5HTT) - RATTUS NORVEGICUS (RAT).
NTT4_RAT SODIUM- AND CHLORIDE-DEPENDENT TRANSPORTER NTT4 - RATTUS NORVEGICUS (RAT).
NTT7_RAT SODIUM- AND CHLORIDE-DEPENDENT TRANSPORTER NTT73 - RATTUS NORVEGICUS (RAT).
NTTA_CANFA SODIUM- AND CHLORIDE-DEPENDENT TAURINE TRANSPORTER - CANIS FAMILIARIS (DOG).
NTTA_HUMAN SODIUM- AND CHLORIDE-DEPENDENT TAURINE TRANSPORTER - HOMO SAPIENS (HUMAN).
NTTA_MOUSE SODIUM- AND CHLORIDE-DEPENDENT TAURINE AND BETA-ALANINE TRANSPORTER - MUS MUSCULUS (MOUSE).
NTTA_MUSCO SODIUM- AND CHLORIDE-DEPENDENT TAURINE AND BETA-ALANINE TRANSPORTER - MUS COOKII.
NTTA_RAT SODIUM- AND CHLORIDE-DEPENDENT TAURINE TRANSPORTER - RATTUS NORVEGICUS (RAT).
O02003 NEUROTRANSMITTER TRANSPORTER - DROSOPHILA MELANOGASTER (FRUIT FLY).
O17372 T13B5.1 PROTEIN - CAENORHABDITIS ELEGANS.
O42482 L-EPINEPHRINE TRANSPORTER - RANA CATESBEIANA (BULL FROG).
O73771 GABA TRANSPORTER - RAJA SP.
O76188 POTASSIUM COUPLED AMINO ACID TRANSPORTER - MANDUCA SEXTA (TOBACCO HAWKMOTH) (TOBACCO HORNWORM).
O88575 ORPHAN TRANSPORTER - MUS MUSCULUS (MOUSE).
O88576 ORPHAN TRANSPORTER ISOFORM A12 - MUS MUSCULUS (MOUSE).
O88577 ORPHAN TRANSPORTER ISOFORM A11 - MUS MUSCULUS (MOUSE).
P90890 F55H12.1 PROTEIN - CAENORHABDITIS ELEGANS.
Q22116 T03F7.1 PROTEIN - CAENORHABDITIS ELEGANS.
Q23969 COCAINE-SENSITIVE SEROTONIN TRANSPORTER - DROSOPHILA MELANOGASTER (FRUIT FLY).
Q25512 GABA NEUROTRANSMITTER TRANSPORTER - MANDUCA SEXTA (TOBACCO HAWKMOTH) (TOBACCO HORNWORM).
Q62687 RENAL OSMOTIC STRESS-INDUCED NA-CL ORGANIC SOLUTE COTRANSPORTER - RATTUS NORVEGICUS (RAT).
Q63380 NOREPINEPHRINE TRANSPORTER (NACL-DEPENDENT NOREPINEPHRINE TRANSPORTER) - RATTUS NORVEGICUS (RAT).
Q64093 NEUROTRANSMITTER TRANSPORTER RB21A - RATTUS NORVEGICUS (RAT).
Q91494 GAT-1 GABA TRANSPORTER - TORPEDO CALIFORNICA (PACIFIC ELECTRIC RAY).
Q91502 CREATINE TRANSPORTER - TORPEDO MARMORATA (MARBLED ELECTRIC RAY).
Q91503 GABA/BETA-ALANINE TRANSPORTER - TORPEDO MARMORATA (MARBLED ELECTRIC RAY).
Q94917 INEBRIATED - DROSOPHILA MELANOGASTER (FRUIT FLY).
YN05_CAEEL PUTATIVE SODIUM- AND CHLORIDE-DEPENDENT TRANSPORTER T23G5.5 IN CHROMOSOME III - CAENORHABDITIS ELEGANS.

O88578 ORPHAN TRANSPORTER ISOFORM B11 - MUS MUSCULUS (MOUSE).
O88579 ORPHAN TRANSPORTER ISOFORM A10 - MUS MUSCULUS (MOUSE).

O45813 T25B6.7 PROTEIN - CAENORHABDITIS ELEGANS.
O88580 ORPHAN TRANSPORTER ISOFORM B9 - MUS MUSCULUS (MOUSE).

O50649 TNA2, TNA1, PARTIAL AND COMPLETE CDS - SYMBIOBACTERIUM THERMOPHILUM.
O88581 ORPHAN TRANSPORTER ISOFORM A8 - MUS MUSCULUS (MOUSE).
Q13032 GABA/NORADRENALINE TRANSPORTER - HOMO SAPIENS (HUMAN).

O28284 SODIUM- AND CHLORIDE-DEPENDENT TRANSPORTER - ARCHAEOGLOBUS FULGIDUS.
YD19_METJA HYPOTHETICAL SODIUM-DEPENDENT TRANSPORTER MJ1319 - METHANOCOCCUS JANNASCHII.

O34383 PUTATIVE TRANSPORTER - BACILLUS SUBTILIS.
O50080 521AA LONG HYPOTHETICAL SODIUM-DEPENDENT TRANSPORTER - PYROCOCCUS HORIKOSHII.
Y736_HAEIN HYPOTHETICAL SODIUM-DEPENDENT TRANSPORTER HI0736 - HAEMOPHILUS INFLUENZAE.
YG90_HAEIN HYPOTHETICAL SODIUM-DEPENDENT TRANSPORTER HI1690 - HAEMOPHILUS INFLUENZAE.

CINA_ELEEL SODIUM CHANNEL PROTEIN (NA+ CHANNEL) - ELECTROPHORUS ELECTRICUS (ELECTRIC EEL).
O07577 HYPOTHETICAL 48.9 KD PROTEIN - BACILLUS SUBTILIS.
O30781 SODIUM-DEPENDENT TRANSPORTER - CHLAMYDIA PSITTACI.
O67854 NA(+):NEUROTRANSMITTER SYMPORTER (SNF FAMILY) - AQUIFEX AEOLICUS.
O83067 SODIUM- AND CHLORIDE- DEPENDENT TRANSPORTER - TREPONEMA PALLIDUM.
O84234 SODIUM-DEPENDENT AMINO ACID TRANSPORTER - CHLAMYDIA TRACHOMATIS.
Scan History
OWL22_1    2  100  NSINGLE    
OWL26_0 1 100 NSINGLE
SPTR37_9f 3 100 NSINGLE
Initial Motifs
Motif 1  width=22
Element Seqn Id St Int Rpt
DFVLSVAGGFVGLGNVWRFPYL NTTA_CANFA 49 49 -
DFVLSVAGGFVGLGNVWRFPYL NTTA_MUSCO 49 49 -
DFLMSCVGYAIGLGNVWRFPYL NTG1_MOUSE 52 52 -
DFIMSCVGFAVGLGNVWRFPYL NTCR_RABIT 60 60 -
DFLLSVVGFAVDLANVWRFPYL NTNO_HUMAN 64 64 -
DFLLSVIGFAVDLANVWRFPYL NTDO_HUMAN 68 68 -
EFVLTSVGYAVGLGNVWRFPYL NTGL_RAT 35 35 -
DFLLSVIGYAVDLGNIWRFPYI NTS2_RAT 87 87 -
EFVLSVAGEIIGLGNVWRFPYL NTBE_CANFA 44 44 -

Motif 2 width=20
Element Seqn Id St Int Rpt
AFLIPYFIFLFGGGLPVFFL NTTA_CANFA 78 7 -
AFLIPYFLTLIFAGVPLFLL NTG1_MOUSE 81 7 -
VFLIPYVLIALVGGIPIFFL NTCR_RABIT 89 7 -
AFLIPYTLFLIIAGMPLFYM NTNO_HUMAN 93 7 -
AFLVPYLLFMVIAGMPLFYM NTDO_HUMAN 97 7 -
AFMFPYFIMLVFCGIPLFFM NTGL_RAT 64 7 -
AFLLPYTIMAIFGGIPLFYM NTS2_RAT 116 7 -
AFFIPYFIFFFTCGIPVFFL NTBE_CANFA 73 7 -
AFLIPYFIFLFGSGLPVFFL NTTA_MUSCO 78 7 -

Motif 3 width=27
Element Seqn Id St Int Rpt
GIAYASIVIVSLLNVYYIVILAWATYY NTTA_MUSCO 122 24 -
GLGYASMVIVFYCNTYYIMVLAWGFYY NTCR_RABIT 132 23 -
GIGYAICIIAFYIASYYNTIIAWALYY NTS2_RAT 160 24 -
GVGYGMMVVSTYIGIYYNVVICIAFYY NTGL_RAT 107 23 -
GVGFTVILISLYVGFFYNVIIAWALHY NTDO_HUMAN 140 23 -
GVGYAVILIALYVGFYYNVIIAWSLYY NTNO_HUMAN 136 23 -
GIGLASVVIESYLNIYYIIILAWALFY NTBE_CANFA 117 24 -
GIGYASIVIVSLLNIYYVIILAWATYY NTTA_CANFA 122 24 -
GVAVAAAVLSFWLNIYYIVIISWAIYY NTG1_MOUSE 124 23 -

Motif 4 width=18
Element Seqn Id St Int Rpt
IVYFTATFPYVVLVVLLV NTCR_RABIT 260 101 -
VVWVTATFPYIVLSVLLV NTS2_RAT 280 93 -
VVYFTATFPYLMLVILLI NTBE_CANFA 238 94 -
VVYFTATFPFAMLLVLLV NTTA_CANFA 245 96 -
VVYFTATFPFAMLLVLLV NTTA_MUSCO 245 96 -
VVYFSATYPYIMLIILFF NTG1_MOUSE 238 87 -
VVWITATLPYFVLFVLLV NTNO_HUMAN 262 99 -
VVWITATMPYVVLTALLL NTDO_HUMAN 265 98 -
VVYFTATFPYVVLTILFV NTGL_RAT 242 108 -

Motif 5 width=21
Element Seqn Id St Int Rpt
LLTSSINCITSFVSGFAIFSI NTNO_HUMAN 344 64 -
LVTSVVNCMTSFVSGFVIFTV NTS2_RAT 362 64 -
VIISITNCATSVYAGFVIFSI NTGL_RAT 324 64 -
IVTTSINSLTSFSSGFVVFSF NTDO_HUMAN 347 64 -
IALCFLNSATSFAAGFVVFSI NTBE_CANFA 320 64 -
MLLGCLNSGTSFVSGFAIFSI NTTA_CANFA 327 64 -
MLLGCLNSGTSFVSGFAIFSI NTTA_MUSCO 327 64 -
IIVCCINSCTSMFAGFVIFSI NTG1_MOUSE 320 64 -
IILALINSGTSFFAGFVVFSI NTCR_RABIT 342 64 -

Motif 6 width=20
Element Seqn Id St Int Rpt
LPLSSAWAVVFFIMLLTLGI NTDO_HUMAN 401 33 -
MPLSQLWSCLFFIMLIFLGL NTBE_CANFA 374 33 -
MPLPTFWSILFFIMLLLLGL NTTA_CANFA 381 33 -
MPLPTFWSILFFIMLLLLGL NTTA_MUSCO 381 33 -
LPISPLWAILFFSMLLMLGI NTG1_MOUSE 374 33 -
MPVAPLWAALFFFMLLLLGL NTCR_RABIT 396 33 -
LSGSTFWAVVFFVMLLALGL NTNO_HUMAN 398 33 -
LPISPLWSLLFFFMLILLGL NTGL_RAT 378 33 -
MPASTFFAIIFFLMLITLGL NTS2_RAT 417 34 -

Motif 7 width=21
Element Seqn Id St Int Rpt
SFSLVVISCIMCVSIMYIYGH NTGL_RAT 460 62 -
GICLLFLAMFEVICISWVYGA NTBE_CANFA 458 64 -
GVCLLWVAFFECFVIAWIYGS NTTA_CANFA 465 64 -
GVCLLWVAFFECFVIAWIYGG NTTA_MUSCO 465 64 -
GMSLLFLVFFECVSISWFYGV NTG1_MOUSE 456 62 -
GPAVLTVALIEAVAVSWFYGI NTS2_RAT 498 61 -
GTTLLWQAFWECVAVAWVYGA NTCR_RABIT 480 64 -
GTSILFAVLMEAIGVSWFYGV NTNO_HUMAN 478 60 -
GTSILFGVLIEAIGVAWFYGV NTDO_HUMAN 481 60 -

Motif 8 width=21
Element Seqn Id St Int Rpt
KYSWAVITPALCVGCFVFSLV NTTA_MUSCO 505 19 -
KLCWSFFTPIIVAGVFLFSAV NTG1_MOUSE 496 19 -
QICWRFVSPTIIFFILIFTVI NTGL_RAT 500 19 -
RLCWKLVSPCFLLFVVVVSIV NTDO_HUMAN 521 19 -
KISWLFLTPGLCLATFLFSLS NTBE_CANFA 498 19 -
RICWVAISPLFLLFIICSFLM NTS2_RAT 537 18 -
KWCWSFFTPLVCMGIFIFNIV NTCR_RABIT 520 19 -
KYSWAVVTPVLCVGCFIFSLV NTTA_CANFA 505 19 -
RLCWKFVSPAFLLFVVVVSII NTNO_HUMAN 518 19 -
Final Motifs
Motif 1  width=22
Element Seqn Id St Int Rpt
EFVLSVAGEIIGLGNVWRFPYL NTBE_HUMAN 44 44 -
EFVLSVAGEIIGLGNVWRFPYL NTG3_MOUSE 53 53 -
EFVLSVAGEIIGLGNVWRFPYL NTG3_RAT 53 53 -
EFVLSVAGEIIGLGNVWRFPYL NTBE_CANFA 44 44 -
DFLMSCVGYAIGLGNVWRFPYL NTG1_HUMAN 52 52 -
EFVLSVAGEIIGLGNVWRFPYL NTBE_RAT 44 44 -
EFVLSVAGEIIGLGNVWRFPYL NTBE_MOUSE 44 44 -
DFVLSVAGGFVGLGNVWRFPYL NTTA_RAT 49 49 -
DFLMSCVGYAIGLGNVWRFPYL NTG1_MUSCO 52 52 -
DFLMSCVGYAIGLGNVWRFPYL NTG1_RAT 52 52 -
DFVLSVAGGFVGLGNVWRFPYL NTTA_HUMAN 49 49 -
DFVLSVAGGFVGLGNVWRFPYL NTTA_CANFA 49 49 -
DFVLSVAGGFVGLGNVWRFPYL NTTA_MOUSE 49 49 -
EFVLSVAGEIIGLGNVWRFPYL NTG3_HUMAN 58 58 -
DFVLSVAGGFVGLGNVWRFPYL NTTA_MUSCO 49 49 -
DFLMSCVGYAIGLGNVWRFPYL NTG1_MOUSE 52 52 -
EFVLSVAGEIIGLSNVWRFPYL NTBE_RABIT 44 44 -
EFVLSVAGEIIGLGNVWRFPYL Q91503 46 46 -
EFVLSVAGEIIGLGNVWRFPYL NTG2_RAT 40 40 -
DFIMSCVGFAVGLGNVWRFPYL NTCR_RABIT 60 60 -
EFVLSVAGEIIGLGNVWRFPYL NTG2_MOUSE 40 40 -
DFIMSCVGFAVGLGNVWRFPYL NTCR_BOVIN 60 60 -
DFIMSCVGFAVGLGNVWRFPYL NTCH_RAT 60 60 -
DFIMSCVGFAVGLGNVWRFPYL NTCR_HUMAN 60 60 -
DFLLSCVGYAIGLGNVWRFPYL Q91494 51 51 -
EFLLSCVGYAIGLGNVWRFPYL O73771 51 51 -
DFLLSVVGFAVDLANVWRFPYL Q63380 64 64 -
DFLLSVVGFAVDLANVWRFPYL NTNO_MOUSE 64 64 -
DFLLSVVGFAVDLANVWRFPYL NTNO_HUMAN 64 64 -
DFLLSVVGFAVDLANVWRFPYL NTNO_BOVIN 62 62 -
DFILSVIGLAIGLGNVWRFPYL Q25512 43 43 -
DFLLSVVGFSVDLANVWRFPYL O42482 77 77 -
DFIMSCVGFAVGLGNVWRFPYL Q91502 44 44 -
EFLLAVIGFAVDLGNVWRFPYI Q23969 41 41 -
EFLLAVIGFAVDLGNVWRFPYI NTSE_DROME 82 82 -
EFVLTSVGYAVGLGNVWRFPYL NTGL_BOVIN 40 40 -
DFLLSVIGYAVDLGNIWRFPYI NTSE_RAT 87 87 -
DFLLSVIGYAVDLGNIWRFPYI NTSE_MOUSE 87 87 -
DFLLSVIGFAVDLANVWRFPYL NTDO_RAT 68 68 -
DFLLSVIGYAVDLGNIWRFPYV NTSE_CAVPO 87 87 -
DFLLSVIGFAVDLANVWRFPYL NTDO_HUMAN 68 68 -
DFLLSVIGYAVDLGNVWRFPYI NTSE_HUMAN 87 87 -
DFLLSVIGFAVDLANVWRFPYL NTDO_BOVIN 68 68 -
EFVLTSVGYAVGLGNVWRFPYL NTGL_HUMAN 94 94 -
EFVLTSVGYAVGLGNVWRFPYL NTGL_RAT 35 35 -
EFVLTSVGYAVGLGNVWRFPYL NTGL_MOUSE 35 35 -
DFIMSCIGYAIGLGNVWRFPYL Q22116 40 40 -
DFLLSCIGYCVGLGNVWRFPYR NTPR_RAT 45 45 -
DFLLSVVGFAVDLGNIWRFPYL YN05_CAEEL 29 29 -
QFVFACISYAVGLGNVWRFPYL Q64093 37 37 -
QYLLSCIGFAVGLGNIWRFPYL Q62687 25 25 -
QYLLSCIGFAVGLGNIWRFPYL O88577 25 25 -
QYLLSCIGFAVGLGNIWRFPYL O88576 25 25 -
QFLLVCISYAVGLGNVWRFPYL O88575 56 56 -
QFVLACIGYSVGLGNVWRFPYM Q94917 60 60 -
QFVLACIGYSVGLGNVWRFPYM O02003 345 345 -
QYILAQVGFSVGLGNVWRFPYL NTT7_RAT 69 69 -
DFLMSMVAYAVGLGNVWRFPYL O17372 47 47 -
QYILAQIGFSVGLGNIWRFPYL NTT4_RAT 68 68 -
EFLMSCIATSVGLGNVWRFPFI O76188 59 59 -
ESLLSSLGQAIGLGNIWRFPTV P90890 116 116 -

Motif 2 width=20
Element Seqn Id St Int Rpt
AFFIPYFIFFFVCGIPVFFL NTBE_HUMAN 73 7 -
AFLIPYVVFFICCGIPVFFL NTG3_MOUSE 82 7 -
AFLIPYVVFFICCGIPVFFL NTG3_RAT 82 7 -
AFFIPYFIFFFTCGIPVFFL NTBE_CANFA 73 7 -
AFLIPYFLTLIFAGVPLFLL NTG1_HUMAN 81 7 -
AFFIPYFIFFFSCGIPVFFL NTBE_RAT 73 7 -
AFFIPYFIFFFSCGIPVFFL NTBE_MOUSE 73 7 -
AFLIPYFIFLFGSGLPVFFL NTTA_RAT 78 7 -
AFLIPYFLTLIFAGVPLFLL NTG1_MUSCO 81 7 -
AFLIPYFLTLIFAGVPLFLL NTG1_RAT 81 7 -
AFLIPYFIFLFGSGLPVFFL NTTA_HUMAN 78 7 -
AFLIPYFIFLFGGGLPVFFL NTTA_CANFA 78 7 -
AFLIPYFIFLFGSGLPVFFL NTTA_MOUSE 78 7 -
AFLIPYVVFFICCGIPVFFL NTG3_HUMAN 87 7 -
AFLIPYFIFLFGSGLPVFFL NTTA_MUSCO 78 7 -
AFLIPYFLTLIFAGVPLFLL NTG1_MOUSE 81 7 -
AFFVPYFIFFFSCGIPVFFL NTBE_RABIT 73 7 -
AFLIPYVIFFIGCGIPVFFL Q91503 75 7 -
AFFIPYLIFLFTCGIPVFFL NTG2_RAT 69 7 -
VFLIPYVLIALVGGIPIFFL NTCR_RABIT 89 7 -
AFFIPYLIFLFTCGIPVFFL NTG2_MOUSE 69 7 -
VFLIPYILIALIGGIPIFFL NTCR_BOVIN 89 7 -
VFLIPYVLIALVGGIPIFFL NTCH_RAT 89 7 -
VFLIPYVLIALVGGIPIFFL NTCR_HUMAN 89 7 -
AFLIPYFMTLIFAGMPIFLL Q91494 80 7 -
AFLIPYFLTLIFAGMPIFLL O73771 80 7 -
AFLIPYTLFLIIAGMPLFYM Q63380 93 7 -
AFLIPYTLFLIIAGMPLFYM NTNO_MOUSE 93 7 -
AFLIPYTLFLIIAGMPLFYM NTNO_HUMAN 93 7 -
AFLIPYTLFLIIAGMPLFYM NTNO_BOVIN 91 7 -
AFLIPYFLTLFLAGIPMFFM Q25512 72 7 -
AFLIPYTLFLIIAGMPLFYM O42482 106 7 -
VFLIPYLLVAVFGGIPIFFL Q91502 73 7 -
AFLVPYCLFLIFGGLPLFYM Q23969 70 7 -
AFLVPYCLFLIFGGLPLFYM NTSE_DROME 111 7 -
AFMFPYFIMLIFCGIPLFFM NTGL_BOVIN 69 7 -
AFLLPYTIMAIFGGIPLFYM NTSE_RAT 116 7 -
AFLLPYTIMAIFGGIPLFYM NTSE_MOUSE 116 7 -
AFLVPYLLFMVIAGMPLFYM NTDO_RAT 97 7 -
AFLLPYIIMAIFGGIPLFYM NTSE_CAVPO 116 7 -
AFLVPYLLFMVIAGMPLFYM NTDO_HUMAN 97 7 -
AFLLPYTIMAIFGGIPLFYM NTSE_HUMAN 116 7 -
AFLVPYLFFMVVAGVPLFYM NTDO_BOVIN 97 7 -
AFMFPYFIMLIFCGIPLFFM NTGL_HUMAN 123 7 -
AFMFPYFIMLVFCGIPLFFM NTGL_RAT 64 7 -
AFMFPYFIMLIFCGIPLFFM NTGL_MOUSE 64 7 -
AFLIPYCISLVFCGAPLFIL Q22116 69 7 -
AFLVPYFLMLAICGIPLFFL NTPR_RAT 74 7 -
VFLIPYSIMVLLTGVPLFYM YN05_CAEEL 58 7 -
SFLVPYLIMLIVEGMPLLYL Q64093 66 7 -
AFLIPYFIALVFEGIPLFYI Q62687 54 7 -
AFLIPYFIALVFEGIPLFYI O88577 54 7 -
AFLIPYFIALVFEGIPLFYI O88576 54 7 -
SFLVPYIIMLIVEGMPLLYL O88575 85 7 -
VFLVPYCIILFICSIPLLFM Q94917 89 7 -
VFLVPYCIILFICSIPLLFM O02003 374 7 -
AYLLPYLILLLVIGIPLFFL NTT7_RAT 98 7 -
SFLVVYMIFFCLAAVPIFLM O17372 76 7 -
AYLVPYLVLLIIIGIPLFFL NTT4_RAT 97 7 -
AFLVPYIIVLLLVGKPVYYL O76188 88 7 -
SFLIVYIICAFVFAVPAIHM P90890 145 7 -

Motif 3 width=27
Element Seqn Id St Int Rpt
GIGLASVVIESYLNVYYIIILAWALFY NTBE_HUMAN 117 24 -
GIGYATQVIEAHLNVYYIIILAWAIFY NTG3_MOUSE 126 24 -
GIGYATQVIEAHLNVYYIIILAWAIFY NTG3_RAT 126 24 -
GIGLASVVIESYLNIYYIIILAWALFY NTBE_CANFA 117 24 -
GVGLAAAVLSFWLNIYYIVIISWAIYY NTG1_HUMAN 124 23 -
GIGMASVVIESYLNIYYIIILAWALFY NTBE_RAT 117 24 -
GIGMASVVIESYLNIYYIIILAWALFY NTBE_MOUSE 117 24 -
GIGYASIVIVSLLNVYYIVILAWATYY NTTA_RAT 122 24 -
GVGLAAAVLSFWLNIYYIVIISWAIYY NTG1_MUSCO 124 23 -
GVGLAAAVLSFWLNIYYIVIISWAIYY NTG1_RAT 124 23 -
GIGYASVVIVSLLNVYYIVILAWATYY NTTA_HUMAN 122 24 -
GIGYASIVIVSLLNIYYVIILAWATYY NTTA_CANFA 122 24 -
GIGYASIVIVSLLNVYYIVILAWATYY NTTA_MOUSE 122 24 -
GIGYATQVIEAHLNVYYIIILAWAIFY NTG3_HUMAN 131 24 -
GIAYASIVIVSLLNVYYIVILAWATYY NTTA_MUSCO 122 24 -
GVAVAAAVLSFWLNIYYIVIISWAIYY NTG1_MOUSE 124 23 -
GIGLASVVIESYLNVYYIIILAWALFY NTBE_RABIT 117 24 -
GIGYATQVIEAHLNMFYIIVLAWAIFY Q91503 119 24 -
GIGYASQMIVSLLNVYYIVVLAWALFY NTG2_RAT 113 24 -
GLGYASMVIVFYCNTYYIMVLAWGFYY NTCR_RABIT 132 23 -
GIGYASQMIVSLLNVYYIVVLAWALFY NTG2_MOUSE 113 24 -
GLGYASMVIVFYCNTYYIMVLAWGFYY NTCR_BOVIN 132 23 -
GLGYASMVIVFYCNTYYIMVLAWGFYY NTCH_RAT 132 23 -
GLGYASMVIVFYCNTYYIMVLAWGFYY NTCR_HUMAN 132 23 -
GVGLAAAVLSFWLNIYYVVIIAWAIYY Q91494 123 23 -
GVGLAAAVLSFWLNIYYVVIIAWAIYY O73771 123 23 -
GVGYAVILIALYVGFYYNVIIAWSLYY Q63380 136 23 -
GVGYAVILIALYVGFYYNVIIAWSLYY NTNO_MOUSE 136 23 -
GVGYAVILIALYVGFYYNVIIAWSLYY NTNO_HUMAN 136 23 -
GVGYAVILIALYVGFYYNVIIAWSLYY NTNO_BOVIN 134 23 -
GIGYAAAVMSCWMNVYYIVILAWAIFY Q25512 115 23 -
GVGYTVILIALYVGFYYNVIIAWSLYY O42482 149 23 -
GLGYASMVIVFFCNTYYILVLTWSSFY Q91502 116 23 -
GVGYAICLIDIYMGMYYNTIIGWAVYY Q23969 114 24 -
GVGYAICLIDIYMGMYYNTIIGWAVYY NTSE_DROME 155 24 -
GVGYGMMVVSTYIGIYYNVVICIAFYY NTGL_BOVIN 112 23 -
GIGYAICIIAFYIASYYNTIIAWALYY NTSE_RAT 160 24 -
GIGYAICIIAFYIASYYNTIIAWALYY NTSE_MOUSE 160 24 -
GVGFTVILISFYVGFFYNVIIAWALHY NTDO_RAT 140 23 -
GIGYTICIIAFYIASYYNTIIAWALYY NTSE_CAVPO 160 24 -
GVGFTVILISLYVGFFYNVIIAWALHY NTDO_HUMAN 140 23 -
GIGYAICIIAFYIASYYNTIMAWALYY NTSE_HUMAN 160 24 -
GVGYTAILISLYIGFFYNVIIAWALHY NTDO_BOVIN 140 23 -
GVGYGMMVVSTYIGIYYNVVICIAFYY NTGL_HUMAN 166 23 -
GVGYGMMVVSTYIGIYYNVVICIAFYY NTGL_RAT 107 23 -
GVGYGMMVVSTYIGIYYNVVICIAFYY NTGL_MOUSE 107 23 -
GVGIAAAVMAFWLNIYYIVVLSWAATY Q22116 112 23 -
GAGAAMLLIVGLVAIYYNMIIAYVLFY NTPR_RAT 117 23 -
GIGYCVILTAFYVDFFYNVILAWGLHY YN05_CAEEL 102 24 -
GVGVASVVVSFFLSMYYNVINAWGFWY Q64093 110 24 -
GVGLGCFSVSFLVSLYYNTILLWVLWF Q62687 98 24 -
GVGLGCFSVSFLVSLYYNTVLLWVLWF O88577 98 24 -
GVGLGCFSVSFLVSLYYNTVLLWVLWF O88576 98 24 -
GVGIASLVVSFLASVYFNVINTWALWY O88575 129 24 -
GAGLASVVVSFLMSTYYSVIIGYSIYY Q94917 133 24 -
GAGLASVVVSFLMSTYYSVIIGYSIYY O02003 418 24 -
GIGFASCVVCYFVALYYNVIIGWTLFY NTT7_RAT 142 24 -
GVGIGNVVIAFMCIAYFCVIVAWAMFY O17372 119 23 -
GIGFSSCIVCLFVGLYYNVIIGWSVFY NTT4_RAT 141 24 -
GTGYAQAVGCGYILSYYVVICGLCLFY O76188 131 23 -
GVGWMTCIVGAVIGVYYMILISWIVLY P90890 189 24 -

Motif 4 width=18
Element Seqn Id St Int Rpt
VVYFTATFPYLMLVILLI NTBE_HUMAN 238 94 -
VVYVTATFPYIMLLILLI NTG3_MOUSE 248 95 -
VVYVTATFPYIMLLILLI NTG3_RAT 248 95 -
VVYFTATFPYLMLVILLI NTBE_CANFA 238 94 -
VVYFSATYPYIMLIILFF NTG1_HUMAN 239 88 -
VVYFTATFPYLMLIILLI NTBE_RAT 238 94 -
VVYFTATFPYLMLIILLI NTBE_MOUSE 238 94 -
VVYFTATFPFAMLLVLLV NTTA_RAT 245 96 -
VVYFSATYPYIMLIILFF NTG1_MUSCO 238 87 -
VVYFSATYPYIMLIILFF NTG1_RAT 239 88 -
VVYFTATFPFAMLLVLLV NTTA_HUMAN 245 96 -
VVYFTATFPFAMLLVLLV NTTA_CANFA 245 96 -
VVYFTATFPFAMLLVLLV NTTA_MOUSE 245 96 -
VVYVTATFPYIMLLILLI NTG3_HUMAN 253 95 -
VVYFTATFPFAMLLVLLV NTTA_MUSCO 245 96 -
VVYFSATYPYIMLIILFF NTG1_MOUSE 238 87 -
VVYFTATFPYLMLVILLI NTBE_RABIT 238 94 -
VVYVTATFPYLMLLVLLI Q91503 241 95 -
VVYFTATFPYLMLVVLLI NTG2_RAT 233 93 -
IVYFTATFPYVVLVVLLV NTCR_RABIT 260 101 -
VVYFTATFPYLMLVVLLI NTG2_MOUSE 233 93 -
IVYFTATFPYVVLVVLLV NTCR_BOVIN 260 101 -
IVYFTATFPYVVLVVLLV NTCH_RAT 260 101 -
IVYFTATFPYVVLVVLLV NTCR_HUMAN 260 101 -
VVYFSAIYPYIMLLTLFF Q91494 238 88 -
VVYFSAIYPYIMLLTLFF O73771 238 88 -
VVWITATLPYFVLFVLLV Q63380 262 99 -
VVWITATLPYFVLFVLLV NTNO_MOUSE 262 99 -
VVWITATLPYFVLFVLLV NTNO_HUMAN 262 99 -
VVWITATLPYLVLFVLLV NTNO_BOVIN 260 99 -
VVYFTALFPYFLLTVLLI Q25512 252 110 -
VVWITATLPYVVLFVLLI O42482 275 99 -
VVYVTATFPYIILVILLV Q91502 237 94 -
VVWVTALAPYVVLIILLV Q23969 231 90 -
VVWVTALAPYVVLIILLV NTSE_DROME 272 90 -
VVYFTATFPYVVLTILFI NTGL_BOVIN 247 108 -
VVWVTATFPYIVLSVLLV NTSE_RAT 280 93 -
VVWVTATFPYIVLSVLLV NTSE_MOUSE 280 93 -
VVWITATMPYVVLTALLL NTDO_RAT 264 97 -
VVWVTATFPYIVLSVLLV NTSE_CAVPO 280 93 -
VVWITATMPYVVLTALLL NTDO_HUMAN 265 98 -
VVWVTATFPYIILSVLLV NTSE_HUMAN 280 93 -
VVWITATMPYVVLFALLL NTDO_BOVIN 262 95 -
VVYFTATFPYVVLTILFV NTGL_HUMAN 301 108 -
VVYFTATFPYVVLTILFV NTGL_RAT 242 108 -
VVYFTATFPYVVLTILFV NTGL_MOUSE 242 108 -
VVYITASFPYMMLFCLLI Q22116 270 131 -
VVYFTATFPYLILLMLLV NTPR_RAT 242 98 -
VVWFTALFPYVVLGILFI YN05_CAEEL 239 110 -
VVYFTALMPYCVLIIYLV Q64093 219 82 -
VIYFTALFPYLVLTIFLI Q62687 207 82 -
VIYFTALFPYLVLTIFLI O88577 207 82 -
VIYFTALFPYLVLTIFLI O88576 207 82 -
VVYFTTSLPYFVLIIYLV O88575 238 82 -
VRYFTATFPFVLIIILMV Q94917 252 92 -
VRYFTATFPFVLIIILMV O02003 537 92 -
IMYFSSLFPYVVLICFLI NTT7_RAT 253 84 -
FVYFCALFPYVLIFILLI O17372 246 100 -
VMYFSSLFPYVVLACFLV NTT4_RAT 252 84 -
AAYFLALFPYVVMITLFI O76188 250 92 -
LSYVTVILPYFIIVSLLI P90890 346 130 -

Motif 5 width=21
Element Seqn Id St Int Rpt
IALCFLNSATSFVAGFVVFSI NTBE_HUMAN 320 64 -
IMLCCLNSGTSFVAGFAIFSV NTG3_MOUSE 330 64 -
IMLCCLNSGTSFVAGFAIFSV NTG3_RAT 330 64 -
IALCFLNSATSFAAGFVVFSI NTBE_CANFA 320 64 -
IIVCCINSCTSMFAGFVIFSI NTG1_HUMAN 321 64 -
IALCFLNSATSFVAGFVVFSI NTBE_RAT 320 64 -
IALCFLNSATSFVAGFVVFSI NTBE_MOUSE 320 64 -
MLLGCLNSGTSFVSGFAIFSI NTTA_RAT 327 64 -
IIVCCINSCTSMFAGFVIFSI NTG1_MUSCO 320 64 -
IIVCCINSCTSMFAGFVIFSI NTG1_RAT 321 64 -
MLLGCLNSGTSFVSGFAIFSI NTTA_HUMAN 327 64 -
MLLGCLNSGTSFVSGFAIFSI NTTA_CANFA 327 64 -
MLLGCLNSGTSFVLGFAIFSI NTTA_MOUSE 327 64 -
IMLCCLNSGTSFVAGFAIFSV NTG3_HUMAN 335 64 -
MLLGCLNSGTSFVSGFAIFSI NTTA_MUSCO 327 64 -
IIVCCINSCTSMFAGFVIFSI NTG1_MOUSE 320 64 -
IALCFLNSATSFVAGFVVFSV NTBE_RABIT 320 64 -
IMLCCLNSGTSFVAGFAIFSV Q91503 323 64 -
VALCILNSSTSFVAGFAIFSI NTG2_RAT 315 64 -
IILALINSGTSFFAGFVVFSI NTCR_RABIT 342 64 -
IALCILNSSTSFMAGFAIFSI NTG2_MOUSE 315 64 -
IILALINSGTSFFAGFVVFSI NTCR_BOVIN 342 64 -
IILALINSGTSFFAGFVVFSI NTCH_RAT 342 64 -
IILALINSGTSFFAGFVVFSI NTCR_HUMAN 342 64 -
IIVCCINSTTSMFAGFVIFSI Q91494 320 64 -
IIVCCINSTTSMFAGFVIFSI O73771 320 64 -
LLTSTINCVTSFISGFAIFSI Q63380 344 64 -
LLTSTINCVTSFISGFAIFSI NTNO_MOUSE 344 64 -
LLTSSINCITSFVSGFAIFSI NTNO_HUMAN 344 64 -
LLTSTINCVTSFISGFAIFSI NTNO_BOVIN 342 64 -
LIVCSVNSSTSMFAGFVIFSV Q25512 334 64 -
LLTSTINCVTSFISGFAIFSI O42482 357 64 -
FILSLVNSATSFFAGLVVFSI Q91502 319 64 -
LITSSINCLTSFLAGFVIFSV Q23969 313 64 -
LITSSINCLTSFLAGFVIFSV NTSE_DROME 354 64 -
VIISITNCATSVYAGFVIFSI NTGL_BOVIN 329 64 -
LVTSVVNCMTSFVSGFVIFTV NTSE_RAT 362 64 -
LVTSVVNCMTSFVSGFVIFTV NTSE_MOUSE 362 64 -
IITTSINSLTSFSSGFVVFSF NTDO_RAT 346 64 -
LVTSAVNCMTSFVSGFVIFTV NTSE_CAVPO 362 64 -
IVTTSINSLTSFSSGFVVFSF NTDO_HUMAN 347 64 -
LVTSVVNCMTSFVSGFVIFTV NTSE_HUMAN 362 64 -
IITTSVNSLTSFSSGFVVFSF NTDO_BOVIN 344 64 -
VIISITNCATSVYAGFVIFSI NTGL_HUMAN 383 64 -
VIISITNCATSVYAGFVIFSI NTGL_RAT 324 64 -
VIISITNCATRLYAGFVIFSI NTGL_MOUSE 324 64 -
LTVCFVNSGTSVFAGFVIFSF Q22116 352 64 -
FIVTLGNAITSILAGFAIFSV NTPR_RAT 324 64 -
LFTSFINCATSFLSGFVIFSV YN05_CAEEL 321 64 -
VIVSVINSSTSIFASIVTFSI Q64093 301 64 -
VTIALVNSMTSLYASITIFSI Q62687 289 64 -
VIIALVNSMTSLYASIAIFSV O88577 289 64 -
VIIALVNSMTSLYASIAIFSV O88576 289 64 -
LIVSVINSTTAIFSSIVTFSI O88575 320 64 -
VAVSAVNMITSLLVGIFAFST Q94917 334 64 -
VAVSAVNMITSLLVGIFAFST O02003 619 64 -
VLVSFINFFTSVLATLVVFAV NTT7_RAT 335 64 -
ITMCFINGCTSITAGFAVFSI O17372 328 64 -
ALVSFINFFTSVLATLVVFAV NTT4_RAT 334 64 -
LIVTTLDTFTSFLSGCTIFGI O76188 332 64 -
YIIVFLDTLMSILGGITVFST P90890 429 65 -

Motif 6 width=20
Element Seqn Id St Int Rpt
MPLSQLWSCLFFIMLIFLGL NTBE_HUMAN 374 33 -
MPLSPLWATLFFMMLIFLGL NTG3_MOUSE 384 33 -
MPLSPLWATLFFMMLIFLGL NTG3_RAT 384 33 -
MPLSQLWSCLFFIMLIFLGL NTBE_CANFA 374 33 -
LPISPLWAILFFSMLLMLGI NTG1_HUMAN 375 33 -
MPLSQLWSCLFFLMLLFLGL NTBE_RAT 374 33 -
MPLSQLWSCLFFIMLLFLGL NTBE_MOUSE 374 33 -
MPLPTFWSILFFIMLLLLGL NTTA_RAT 381 33 -
LPISPLWAILFFSMLLMLGI NTG1_MUSCO 374 33 -
LPISPLWAILFFSMLLMLGI NTG1_RAT 375 33 -
MPLPTFWSILFFIMLLLLGL NTTA_HUMAN 381 33 -
MPLPTFWSILFFIMLLLLGL NTTA_CANFA 381 33 -
MPLPTFWSILFFIMLLLLGL NTTA_MOUSE 381 33 -
MPLSPLWATLFFMMLIFLGL NTG3_HUMAN 389 33 -
MPLPTFWSILFFIMLLLLGL NTTA_MUSCO 381 33 -
LPISPLWAILFFSMLLMLGI NTG1_MOUSE 374 33 -
MPLSQLWSCLFFIMLIFLGL NTBE_RABIT 374 33 -
MPLAPLWAFLFFLMLIFLGL Q91503 377 33 -
LPFSPLWACCFFFMVVLLGL NTG2_RAT 369 33 -
MPVAPLWAALFFFMLLLLGL NTCR_RABIT 396 33 -
LPFSPLWACCFFFMVVLLGL NTG2_MOUSE 369 33 -
MPVAPLWAALFFFMLLLLGL NTCR_BOVIN 396 33 -
MPVAPLWAALFFFMLLLLGL NTCH_RAT 396 33 -
MPVAPLWAALFFFMLLLLGL NTCR_HUMAN 396 33 -
LPISPLWSILFFSMLLMLGI Q91494 374 33 -
LPISPFWSILFFSMLLMLGI O73771 374 33 -
LSGSTFWAVLFFLMLLALGL Q63380 398 33 -
LSGSTFWAVLFFLMLLALGL NTNO_MOUSE 398 33 -
LSGSTFWAVVFFVMLLALGL NTNO_HUMAN 398 33 -
LSGSTFWAIVFFIMLLALGI NTNO_BOVIN 396 33 -
LPGAPLWSCLFFFMLLLIGL Q25512 388 33 -
LRGSTFWAVVFFIMLLTLGI O42482 411 33 -
MPFPQVWAVLFFIMLLCLGL Q91502 373 33 -
MSGSVFWSIIFFLMLITLGL Q23969 367 33 -
MSGSVFWSIIFFLMLITLGL NTSE_DROME 408 33 -
LPISPLWSLLFFFMLILLGL NTGL_BOVIN 383 33 -
MPASTFFAIIFFLMLITLGL NTSE_RAT 417 34 -
MPASTFFAIIFFLMLITLGL NTSE_MOUSE 417 34 -
LPLSSAWAAVFFLMLLTLGI NTDO_RAT 400 33 -
MPASTFFAIIFFLMLITLGL NTSE_CAVPO 417 34 -
LPLSSAWAVVFFIMLLTLGI NTDO_HUMAN 401 33 -
MPASTFFAIIFFLMLITLGL NTSE_HUMAN 417 34 -
LPLSSVWAVVFFVMLLTLGI NTDO_BOVIN 398 33 -
LPISPLWSLLFFFMLILLGL NTGL_HUMAN 437 33 -
LPISPLWSLLFFFMLILLGL NTGL_RAT 378 33 -
LPISPLWSLLFFFMLILLGL NTGL_MOUSE 378 33 -
LPYTQFWSCLFFLMVLFLGV Q22116 406 33 -
LPLSPFWSFLFFFMLLTLGL NTPR_RAT 378 33 -
MPYAPFWSVLFFLMLMTLGL YN05_CAEEL 375 33 -
MEVSQLWSVLYFFMLLMLGM Q64093 409 87 -
MPGASVWSVLFFGMLFTLGL Q62687 395 85 -
MPGASVWSVLFFGMLFTLGL O88577 395 85 -
MPGASVWSVLFFGMLFTLGL O88576 395 85 -
MEVSQLWSVLYFFMLLTLGM O88575 428 87 -
MPYAQLWAVMFFFMLLCLGL Q94917 388 33 -
MPYAQLWAVMFFFMLLCLGL O02003 673 33 -
FPASPFWSVMFFLMLINLGL NTT7_RAT 453 97 -
LPMKQVFAVLFFLMITILGL O17372 382 33 -
FPASPFWSVMFFLMLINLGL NTT4_RAT 452 97 -
TFQPQLFSVLFFLMMSVLGI O76188 387 34 -
MPVPYLWYALFFIMLFLLGI P90890 489 39 -

Motif 7 width=21
Element Seqn Id St Int Rpt
GICLLFLSLFEVVCISWVYGA NTBE_HUMAN 458 64 -
GMCLLFVAIFECVCIGWVYGS NTG3_MOUSE 468 64 -
GMCLLFVAIFECVCIGWVYGS NTG3_RAT 468 64 -
GICLLFLAMFEVICISWVYGA NTBE_CANFA 458 64 -
GMSLLFLVFFECVSISWFYGV NTG1_HUMAN 457 62 -
GICLLFLSLFEVICIGWVYGA NTBE_RAT 458 64 -
GICLLFLSLFEVICIGWVYGA NTBE_MOUSE 458 64 -
GVCLLWVAFFECFVIAWIYGG NTTA_RAT 465 64 -
GMSLLFLVFFECVSISWFYGV NTG1_MUSCO 456 62 -
GMSLLFLVFFECVSISWFYGV NTG1_RAT 457 62 -
GVCLLWVAFFECFVIAWIYGG NTTA_HUMAN 465 64 -
GVCLLWVAFFECFVIAWIYGS NTTA_CANFA 465 64 -
GVCLLWVAFFECFVIAWIYGG NTTA_MOUSE 465 64 -
GMCLLFVAIFECICIGWVYGS NTG3_HUMAN 473 64 -
GVCLLWVAFFECFVIAWIYGG NTTA_MUSCO 465 64 -
GMSLLFLVFFECVSISWFYGV NTG1_MOUSE 456 62 -
GICLLFLSVFEVVSISWVYGA NTBE_RABIT 458 64 -
GMCLLFVAIFECICIGWVYGG Q91503 461 64 -
GMCLLFVAIFESLCVAWVYGA NTG2_RAT 453 64 -
GTTLLWQAFWECVAVAWVYGA NTCR_RABIT 480 64 -
GMCLLFVAIFESLCVAWVYGA NTG2_MOUSE 453 64 -
GTTLLWQAFWECVVVAWVYGA NTCR_BOVIN 480 64 -
GTTLLWQAFWECVVVAWVYGA NTCH_RAT 480 64 -
GTTLLWQAFWECVVVAWVYGA NTCR_HUMAN 480 64 -
GMSLLFLVFFETVSISWCYGV Q91494 456 62 -
GMSLLFLVFFETISISWCYGV O73771 456 62 -
GTSILFAVLMEAIGVSWFYGV Q63380 478 60 -
GTSILFAVLMEAIGVSWFYGV NTNO_MOUSE 478 60 -
GTSILFAVLMEAIGVSWFYGV NTNO_HUMAN 478 60 -
GTSILFAVLMEAIGVSWFYGV NTNO_BOVIN 476 60 -
GFCLLFLIFFECVSISWAFGV Q25512 470 62 -
GTSILFAVLIEAVGVSWFYGV O42482 491 60 -
GTTLLWTAFWECVAVAWVYGG Q91502 457 64 -
GLAILFVVFVEAAGVFWFYGV Q23969 448 61 -
GLAILFVVFVEAAGVFWFYGV NTSE_DROME 489 61 -
SFSLVIISCIMCVSIMYIYGH NTGL_BOVIN 465 62 -
GPAVLTVALIEAVAVSWFYGI NTSE_RAT 498 61 -
GPAVLTVALIEAVVVSWFYGI NTSE_MOUSE 498 61 -
GTSILFGVLIEAIGVAWFYGV NTDO_RAT 480 60 -
GPAVLTVVFIEAIAVSWFYGV NTSE_CAVPO 498 61 -
GTSILFGVLIEAIGVAWFYGV NTDO_HUMAN 481 60 -
GPAVLTVALIEAVAVSWFYGI NTSE_HUMAN 498 61 -
GTSILFGVLMEVIGVAWFYGV NTDO_BOVIN 478 60 -
SFSLVVISCIMCVAIMYIYGH NTGL_HUMAN 519 62 -
SFSLVVISCIMCVSIMYIYGH NTGL_RAT 460 62 -
SFSLVVISCIMCVSIMYIYGH NTGL_MOUSE 460 62 -
GWALLWLLFFECIAISWSLGI Q22116 490 64 -
SFGLMVVVITTCLAVTRVYGI NTPR_RAT 459 61 -
TWGLLIAVFCEAMVIAYIYGL YN05_CAEEL 455 60 -
TLSLLLIVLVETIAVCYVYGL Q64093 490 61 -
SLNLIIFAFMEVVGVIHVYGI Q62687 476 61 -
SLNLIIFAFMEVVGVIHIYGM O88577 466 51 -
SLNLIIFAFMEVVGVIHIYGM O88576 476 61 -
TLSLLLIVLVETIAVCYVYGL O88575 509 61 -
SVTIMFLAFCQMIAIAWFYGT Q94917 472 64 -
SVTIMFLAFCQMIAIAWFYGT O02003 757 64 -
TLPLLIVVILENIAVSFVYGI NTT7_RAT 530 57 -
GYALLFVVFFEVVGLAYGFGA O17372 463 61 -
TLPLTVIVILENIAVAWIYGT NTT4_RAT 529 57 -
TFLVLFCAISELAGVFWIYGL O76188 465 58 -
GISATFGTAIMCMTVFWCYGT P90890 569 60 -

Motif 8 width=21
Element Seqn Id St Int Rpt
KISWLFLTPGLCLATFLFSLS NTBE_HUMAN 498 19 -
KWCWKVVTPGICAGIFIFFLV NTG3_MOUSE 508 19 -
KWCWKVVTPGICAGIFIFFLV NTG3_RAT 508 19 -
KISWLFLTPGLCLATFLFSLS NTBE_CANFA 498 19 -
KLCWSFFTPIIVAGVFIFSAV NTG1_HUMAN 497 19 -
KISWLFLTPGLCLATFFFSLS NTBE_RAT 498 19 -
KISWLFLTPGLCLATFFFSLS NTBE_MOUSE 498 19 -
KYSWAVITPALCVGCFIFSLV NTTA_RAT 505 19 -
KLCWSFFTPIIVAGVFLFSAV NTG1_MUSCO 496 19 -
KLCWSFFTPIIVAGVFLFSAV NTG1_RAT 497 19 -
KYSWAVITPVLCVGCFIFSLV NTTA_HUMAN 505 19 -
KYSWAVVTPVLCVGCFIFSLV NTTA_CANFA 505 19 -
KYSWAVITPALCVGCFVFSLV NTTA_MOUSE 505 19 -
KWCWMIMTPGICAGIFIFFLI NTG3_HUMAN 513 19 -
KYSWAVITPALCVGCFVFSLV NTTA_MUSCO 505 19 -
KLCWSFFTPIIVAGVFLFSAV NTG1_MOUSE 496 19 -
KISWLFLTPGLCLATFLFSLS NTBE_RABIT 498 19 -
KWCWIFITPGICAAIFIFFIV Q91503 501 19 -
KYCWLFFTPAVCLATFLFSLI NTG2_RAT 493 19 -
KWCWSFFTPLVCMGIFIFNIV NTCR_RABIT 520 19 -
KYCWLFFTPAVCLATFLFSLI NTG2_MOUSE 493 19 -
KWCWSFFTPLVCMGIFIFNVV NTCR_BOVIN 520 19 -
KWCWSFFTPLVCMGIFIFNVV NTCH_RAT 520 19 -
KWCWSFFTPLVCMGIFIFNVV NTCR_HUMAN 520 19 -
KLCWSFFTPIIVGGVFLFSAI Q91494 496 19 -
KLCWSFFTPIIVGGVFLFSAI O73771 496 19 -
RLCWKFVSPAFLLFVVVVSII Q63380 518 19 -
RLCWKFVSPAFLLFVVVVSII NTNO_MOUSE 518 19 -
RLCWKFVSPAFLLFVVVVSII NTNO_HUMAN 518 19 -
RLCWKFVSPAFLLFVVIVSII NTNO_BOVIN 516 19 -
KFCWVGFTPAICISVFIFNLV Q25512 510 19 -
RLCWKFVSPAFLLFVVITSIV O42482 531 19 -
KWCWSVITPLVCMGIFTFHLV Q91502 497 19 -
RICWTYISPVFLLTIFIFSIM Q23969 488 19 -
RICWTYISPVFLLTIFIFSIM NTSE_DROME 529 19 -
QICWRFVSPAIIFFILIFSVI NTGL_BOVIN 505 19 -
RICWVAISPLFLLFIICSFLM NTSE_RAT 538 19 -
RICWVAISPLFLLFIICSFLM NTSE_MOUSE 538 19 -
RLCWKLVSPCFLLYVVVVSIV NTDO_RAT 520 19 -
RICWVAVSPVFLLFIICSFLM NTSE_CAVPO 538 19 -
RLCWKLVSPCFLLFVVVVSIV NTDO_HUMAN 521 19 -
RICWVAISPLFLLFIICSFLM NTSE_HUMAN 538 19 -
RLCWKFVSPCFLLFVVVVSIA NTDO_BOVIN 518 19 -
QICWRFVSPAIIFFILVFTVI NTGL_HUMAN 559 19 -
QICWRFVSPTIIFFILIFTVI NTGL_RAT 500 19 -
QICWRFVSPAIIFFILIFTVI NTGL_MOUSE 500 19 -
KFCWVFATPSVCFGVLLFGLI Q22116 530 19 -
RACWLFLSPATLLALLVYSIV NTPR_RAT 499 19 -
KFCWSCAAPFILLSMITSNFI YN05_CAEEL 495 19 -
KAMWAFVSPLLIIGLFIFYLS Q64093 530 19 -
QVTWRVVSPMLLFGIFLSYIV Q62687 516 19 -
QVTWRVVSPMLLFGIFLSYIV O88577 506 19 -
QVTWRVVSPMLLFGIFLSYIV O88576 516 19 -
KVMWAFVSPLLIVGLFIFYLS O88575 549 19 -
RSCWLVLGPCLLFAIWVLSLI Q94917 512 19 -
RSCWLVLGPCLLFAIWVLSLI O02003 797 19 -
YYMWKYISPLMLVTLLIASIV NTT7_RAT 570 19 -
EYVWKFCAPATSLVLFVFCVV O17372 503 19 -
FYMWKFVSPLCMAVLTTASII NTT4_RAT 569 19 -
RLCWGIVTPGMMIIVFIYALL O76188 505 19 -
TLIWKFVTPVCSLLMMGLWIW P90890 619 29 -