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PR00122

Identifier
VACATPASE  [View Relations]  [View Alignment]  
Accession
PR00122
No. of Motifs
4
Creation Date
09-MAR-1993  (UPDATE 04-JUL-1999)
Title
Vacuolar ATP synthase 16kD subunit signature
Database References

INTERPRO; IPR000245
Literature References
1. NELSON, H. AND NELSON, N.
The progenitor of ATP synthases was closely related to the current vacuolar
H+-ATPase.
FEBS LETT. 247(1) 147-153 (1989).
 
2. HANADA, H., HASEBE, M., MORIYAMA, Y., MAEDA, M. AND FUTAI, M.
Molecular cloning of cDNA encoding the 16kDa subunit of vacuolar H+-ATPase
from mouse cerebellum.
BIOCHEM.BIOPHYS.RES.COMMUN. 176(3) 1062-1067 (1991).
 
3. MANDEL, M., MORIYAMA, Y., HULMES, J.D., PAN, Y.C.E., NELSON, H. AND 
NELSON, N.
cDNA sequence encoding the 16kDa proteolipid of chromaffin granules implies
gene duplication in the evolution of H+-ATPases.
PROC.NATL.ACAD.SCI.U.S.A. 85(15) 5521-5524 (1988).
 
4. BOWMAN, B.J., DSCHIDA, W.J. AND BOWMAN, E.J.
Vacuolar ATPase of Neurospora crassa: electron microscopy, gene
characterization and gene inactivation/mutation. 
J.EXP.BIOL. 172 57-66 (1992).

Documentation
Several vacuolar organelles of eukaryotic cells have acidic interiors
caused by an electrochemical proton gradient created by vacuolar ATPase 
[1], which continually pumps protons into them. Although the proton
gradient is not great enough to synthesise ATP (even at low concentrations
of ATP), it is essential for some organelle functions, including
accumulation of hormones and neurotransmitters in secretory granules, and
acidification of lysosomes to create optimal conditions for lysozyme
hydrolases [2].
 
Vacuolar ATPase is distinct from 2 other forms of membrane ATPase (plasma
membrane and eubacterial), although the structures of all 3 types are
similar [3]. The protein comprises 2 main domains: a membrane bound domain,
which contains at least 2 different subunits (20kDa and 16kDa); and a
peripheral domain, which contains an ATP hydrolysis site. The 16kDa
subunit of the membrane domain has 4 transmembrane regions, and has been
implicated in the proton-conducting role of the enzyme. Electron microscopy 
studies have shown that vacuolar ATPase has a `ball and stalk' structure
resembling that of the mitochondrial F-ATPase [4].
 
VACATPASE is a 4-element fingerprint that provides a signature for the 
16kDa proteolipid subunit of vacuolar ATP synthase. The fingerprint was 
derived from an initial alignment of 9 sequences: the motifs were drawn
from conserved regions spanning virtually the full alignment length. Two
iterations on OWL19.1 were required to reach convergence, at which point 
a true set comprising 12 sequences was identified. 
 
An update on SPTR37_9f identified a true set of 38 sequences, and 8
partial matches.
Summary Information
  38 codes involving  4 elements
3 codes involving 3 elements
3 codes involving 2 elements
Composite Feature Index
438383838
30333
21122
1234
True Positives
O22037        O22038        O22051        O22052        
O22053 O22054 O62579 VAL1_CAEEL
VAL2_CAEEL VATL_AEDAE VATL_ARATH VATL_ASCSU
VATL_AVESA VATL_BETVU VATL_BOVIN VATL_CANTR
VATL_DICDI VATL_DROME VATL_ENTDI VATL_ENTHI
VATL_GOSHI VATL_HELVI VATL_HUMAN VATL_KALDA
VATL_LYCES VATL_MANSE VATL_MOUSE VATL_NEPNO
VATL_NEUCR VATL_ORYSA VATL_PHAAU VATL_PLECA
VATL_SCHPO VATL_SHEEP VATL_TOBAC VATL_TORMA
VATL_YEAST VM11_YEAST
True Positive Partials
Codes involving 3 elements
O14046 PPA1_YEAST Q99437
Codes involving 2 elements
ATPL_AQUAE O66395 Q22087
Sequence Titles
O22037      VACUOLAR TYPE H+-ATPASE PROTEOLIPID SUBUNIT - ACETABULARIA ACETABULUM. 
O22038 VACUOLAR TYPE H+-ATPASE PROTEOLIPID SUBUNIT - ACETABULARIA ACETABULUM.
O22051 VACUOLAR TYPE H+-ATPASE PROTEOLIPID SUBUNIT - ACETABULARIA ACETABULUM.
O22052 VACUOLAR TYPE H+-ATPASE PROTEOLIPID SUBUNIT - ACETABULARIA ACETABULUM.
O22053 VACUOLAR TYPE H+-ATPASE PROTEOLIPID SUBUNIT - ACETABULARIA ACETABULUM.
O22054 VACUOLAR TYPE H+-ATPASE PROTEOLIPID SUBUNIT - ACETABULARIA ACETABULUM.
O62579 VACUOLAR ATPASE PROTEOLIPID SUBUNIT (EC 3.6.1.35) (H(+)-TRANSPORTING ATPASE) - GIARDIA INTESTINALIS.
VAL1_CAEEL VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT 1 (EC 3.6.1.34) - CAENORHABDITIS ELEGANS.
VAL2_CAEEL VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT 2 (EC 3.6.1.34) - CAENORHABDITIS ELEGANS.
VATL_AEDAE VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) (V-ATPASE C-SUBUNIT) - AEDES AEGYPTI (YELLOWFEVER MOSQUITO).
VATL_ARATH VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) (V- ATPASE 16 KD PROTEOLIPID SUBUNIT) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
VATL_ASCSU VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - ASCARIS SUUM (PIG ROUNDWORM) (ASCARIS LUMBRICOIDES).
VATL_AVESA VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - AVENA SATIVA (OAT).
VATL_BETVU VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - BETA VULGARIS (SUGAR BEET), AND MESEMBRYANTHEMUM CRYSTALLINUM (COMMON ICE PLANT).
VATL_BOVIN VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - BOS TAURUS (BOVINE).
VATL_CANTR VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - CANDIDA TROPICALIS (YEAST).
VATL_DICDI VACUOLAR ATP SYNTHASE PROTEOLIPID SUBUNIT (EC 3.6.1.34) - DICTYOSTELIUM DISCOIDEUM (SLIME MOLD).
VATL_DROME VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) (DUCTIN) - DROSOPHILA MELANOGASTER (FRUIT FLY).
VATL_ENTDI VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) (V- ATPASE 16 KD PROTEOLIPID SUBUNIT) - ENTAMOEBA DISPAR.
VATL_ENTHI VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) (V- ATPASE 16 KD PROTEOLIPID SUBUNIT) - ENTAMOEBA HISTOLYTICA.
VATL_GOSHI VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - GOSSYPIUM HIRSUTUM (UPLAND COTTON).
VATL_HELVI VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - HELIOTHIS VIRESCENS (NOCTUID MOTH) (OWLET MOTH).
VATL_HUMAN VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - HOMO SAPIENS (HUMAN).
VATL_KALDA VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) (V-TYPE H+-ATPASE 16 KD SUBUNIT) - KALANCHOE DAIGREMONTIANA.
VATL_LYCES VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - LYCOPERSICON ESCULENTUM (TOMATO).
VATL_MANSE VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - MANDUCA SEXTA (TOBACCO HAWKMOTH) (TOBACCO HORNWORM).
VATL_MOUSE VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - MUS MUSCULUS (MOUSE), AND RATTUS NORVEGICUS (RAT).
VATL_NEPNO VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - NEPHROPS NORVEGICUS (NORWAY LOBSTER).
VATL_NEUCR VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - NEUROSPORA CRASSA.
VATL_ORYSA VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - ORYZA SATIVA (RICE).
VATL_PHAAU VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - PHASEOLUS AUREUS (MUNG BEAN) (VIGNA RADIATA).
VATL_PLECA VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) (V-ATPASE 16 KD PROTEOLIPID SUBUNIT) - PLEUROCHRYSIS CARTERAE.
VATL_SCHPO VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
VATL_SHEEP VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - OVIS ARIES (SHEEP).
VATL_TOBAC VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - NICOTIANA TABACUM (COMMON TOBACCO).
VATL_TORMA VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) (15 KD MEDIATOPHORE PROTEIN) - TORPEDO MARMORATA (MARBLED ELECTRIC RAY).
VATL_YEAST VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT (EC 3.6.1.34) - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
VM11_YEAST PROTEOLIPID PROTEIN VMA11 - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).

O14046 PUTATIVE PROTEOLIPID PROTEIN C2C4.13 - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
PPA1_YEAST PROTEOLIPID PROTEIN PPA1 - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
Q99437 PROTON-ATPASE-LIKE PROTEIN - HOMO SAPIENS (HUMAN).

ATPL_AQUAE ATP SYNTHASE C CHAIN (EC 3.6.1.34) (LIPID-BINDING PROTEIN) - AQUIFEX AEOLICUS.
O66395 AMMONIUM TRANSPORTER, AMTB - AZORHIZOBIUM CAULINODANS.
Q22087 T01H3.1 PROTEIN - CAENORHABDITIS ELEGANS.
Scan History
OWL19_1    2  100  NSINGLE    
OWL25_3 2 100 NSINGLE
SPTR37_9f 2 231 NSINGLE
Initial Motifs
Motif 1  width=25
Element Seqn Id St Int Rpt
AAYGTAKSGTGIAAMSVMRPELIMK S08261 29 29 -
AAYGTAKSGTGIAAMSVMRPELIMK S19985 27 27 -
AAYGTAKSGVGISAMSVMRPELIMK S108665 29 29 -
AAIGTAKSGIGIAGIGTFKPELIMK A41712 34 34 -
AAYGTAKSGTGIAAMSVMRPELIMK VATL_MOUSE 30 30 -
AAYGTAKSGTGIAAMSVMRPEMIMK VATL_BOVIN 30 30 -
AAYGTAKSGTGIAAMSVMRPEQIMK VATL_HUMAN 30 30 -
AAYGTAKSGTGIAAMSVMRPELIMK VATL_DROME 32 32 -

Motif 2 width=25
Element Seqn Id St Int Rpt
LIPVVMSGILAIYGLVVAVLIAGNL A41712 60 1 -
IIPVVMAGIIAIYGLVVAVLIANSL VATL_MOUSE 56 1 -
IIPVVMAGIIAIYGLVVAVLIANSL VATL_BOVIN 56 1 -
IIPVVMAGIIAIYGLVVAVLIANSL VATL_HUMAN 56 1 -
IIPVVMAGIIAIYGLVVAVLIAGAL VATL_DROME 58 1 -
IIPVVMAGIIAIYGLVVAVLIANSL S08261 55 1 -
IIPVVMAGIIAIYGLVVAVLIAGSL S19985 53 1 -
IIPVVMAGIIAIYGLVVAVLIAGKL S108665 55 1 -

Motif 3 width=27
Element Seqn Id St Int Rpt
LAAGFAIGIVGDAGVRGTAQQPRLFVG VATL_MOUSE 104 23 -
LAAGFAIGIVGDAGVRGTAQQPRLFVG S19985 104 26 -
LAAGFAIGIVGDAGVRGTAQQPRLYVG S108665 105 25 -
LSSGYAIGMVGDVGVRKYMHQPRLFVG A41712 110 25 -
LAAGFAIGIVGDAGVRGTAQQPRLFVG VATL_BOVIN 104 23 -
LAAGFAIGIVGDAGVRGTAQQPRLFVG VATL_HUMAN 104 23 -
LAAGFAIGIVGDAGVRGTAQQPRLFVG VATL_DROME 108 25 -
LAAGFAIGIVGDAGVRGTAQQPRLFVG S08261 103 23 -

Motif 4 width=24
Element Seqn Id St Int Rpt
IVLILIFSEVLGLYGMIVALILNT A41712 137 0 -
MILILIFAEVLGLYGLIVALILST VATL_BOVIN 131 0 -
MILILIFAEVLGLYGLIVALILST VATL_HUMAN 131 0 -
MILILIFAEVLGLYGLIVAIYLYT VATL_DROME 135 0 -
MILILIFAEVLGLYGLIVALILST S08261 130 0 -
MILILIFAEVLGLYGLIVAIYLYT S19985 131 0 -
MILILIFAEVLGLYGLIVAIFLYT S108665 132 0 -
MILILIFAEVLGLYGLIVALILST VATL_MOUSE 131 0 -
Final Motifs
Motif 1  width=25
Element Seqn Id St Int Rpt
AAYGTAKSGVGVASMGVMRPELVMK VATL_AVESA 30 30 -
AAYGTAKSGVGVASMGVMRPELVMK VATL_ORYSA 30 30 -
AAYGTAKSGVGIASMGVMRPELVMK O22054 38 38 -
AAYGTAKSGVGIASMGVMRPELVMK O22053 37 37 -
AAYGTAKSGVGIASMGVMRPELVMK O22052 38 38 -
AAYGTAKSGVGIASMGVMRPELVMK O22038 46 46 -
AAYGTAKSGVGVASMGVMRPELVMK VATL_ARATH 30 30 -
AAYGTAKSGVGVASMGVMRPELVMK VATL_TOBAC 30 30 -
AAYGTAKSGVGVASMGVMRPELVMK VATL_PHAAU 29 29 -
AAYGTAKSGVGVASMGVMRPELVMK VATL_LYCES 29 29 -
AAYGTAKSGVGVASMGVMRPELVMK VATL_KALDA 30 30 -
AAYGTAKSGVGVASMGVMRPELVMK VATL_GOSHI 30 30 -
AAYGTAKSGVGVASMGVMRPELVMK VATL_BETVU 30 30 -
AAYGTAKSGTGIAAMSVMRPELIMK VATL_TORMA 29 29 -
AAYGTAKSGTGIAAMSVMRPELIMK VATL_MOUSE 30 30 -
AAYGTAKSGTGIAAMSVMRPELIMK VATL_MANSE 27 27 -
AAYGTAKSGTGIAAMSVMRPELIMK VATL_HELVI 27 27 -
AAYGTAKSGTGIAAMSVMRPELIMK VATL_AEDAE 30 30 -
AAYGTAKSGTGIAAMSVMRPEMIMK VATL_BOVIN 30 30 -
AAYGTAKSGTGIAAMSVMRPEMIMK VATL_SHEEP 30 30 -
AAYGTAKSGTGIAAMSVMRPEQIMK VATL_HUMAN 30 30 -
AAYGTAKSGTGIAAMSVMRPELIMK VATL_DROME 32 32 -
AAYGTAKSGIGIAQMGVMRPELVMK O22037 32 32 -
AAYGTAKSGVGISAMSVMRPELIMK VATL_NEPNO 29 29 -
AAYGTAKSGIGIAQMGVMKPELVMK O22051 32 32 -
ASYGTAKSGVGIAAMGVLRPDLIVK VATL_NEUCR 28 28 -
AAYGTAKAGVGISAMGVLRPDLIVK VATL_SCHPO 29 29 -
AAYGTAKSGVGVSSMGVMKPDLVMK VATL_PLECA 28 28 -
AAYGTAKSAVGISSMGVMRPELIMK VATL_ASCSU 33 33 -
AAYGTAKSAVGICSMGVMRPELIMK VAL2_CAEEL 33 33 -
ASYGTAKSGVGICATSVTRPDLLVK VATL_CANTR 28 28 -
AAYGTAKSGVGICATCVLRPDLLFK VATL_YEAST 28 28 -
SAYGTAKAGTGIASMAVARPDLVMK VAL1_CAEEL 41 41 -
AAYGTAKASVGISNMGVMKPDLVIK VATL_DICDI 47 47 -
AAIGTAKSGIGIAGIGTFKPELIMK VM11_YEAST 34 34 -
GAYGTAKSSVGISSVGVMKPEFIVR VATL_ENTHI 37 37 -
GAYGTAKSSVGISSVGVMKPEFIMR VATL_ENTDI 35 35 -
AAYGTAKAGSGLGVAGLINPAPVTK O62579 36 36 -

Motif 2 width=25
Element Seqn Id St Int Rpt
IVPVVMAGVLGIYGLIIAVIISTGI VATL_AVESA 56 1 -
IVPVVMAGVLGIYGLIIAVIISTGI VATL_ORYSA 56 1 -
IVPVVMAGVLGIYGLIIAVIISTNV O22054 64 1 -
IVPVVMAGVLGIYGLIIAVIISTNV O22053 63 1 -
IVPVVMAGVLGIYGLIIAVIISTNV O22052 64 1 -
IVPVVMAGVLGIYGLIIAVIISTNV O22038 72 1 -
IVPVVMAGVLGIYGLIIAVIISTGI VATL_ARATH 56 1 -
IVPVVMAGVLGIYGLIIAVIISTGI VATL_TOBAC 56 1 -
IVPVVMAGVLGIYGLIIAVIISTGI VATL_PHAAU 55 1 -
IVPVVMAGVLGIYGLIIAVIISTGI VATL_LYCES 55 1 -
IVPVVMAGVLGIYGLIIAVIISTGI VATL_KALDA 56 1 -
IVPVVMAGVLGIYGLIIAVIISTGI VATL_GOSHI 56 1 -
IVPVVMAGVLGIYGLIIAVIISTGI VATL_BETVU 56 1 -
IIPVVMAGIIAIYGLVVAVLIANSL VATL_TORMA 55 1 -
IIPVVMAGIIAIYGLVVAVLIANSL VATL_MOUSE 56 1 -
IIPVVMAGIIAIYGLVVAVLIAGSL VATL_MANSE 53 1 -
IIPVVMAGIIAIYGLVVAVLIAGSL VATL_HELVI 53 1 -
IIPVVMAGIIAIYGLVVAVLIAGSL VATL_AEDAE 56 1 -
IIPVVMAGIIAIYGLVVAVLIANSL VATL_BOVIN 56 1 -
IIPVVMAGIIAIYGLVVAVLIANSL VATL_SHEEP 56 1 -
IIPVVMAGIIAIYGLVVAVLIANSL VATL_HUMAN 56 1 -
IIPVVMAGIIAIYGLVVAVLIAGAL VATL_DROME 58 1 -
IVPVVMAGVLGIYGLIIAVIISTNV O22037 58 1 -
IIPVVMAGIIAIYGLVVAVLIAGKL VATL_NEPNO 55 1 -
IVPVVMAGVLGIYGLIIAVIISTNV O22051 58 1 -
IVPVIMAGIIGIYGLVVSVLISDAL VATL_NEUCR 54 1 -
TIPVVMAGIIAIYGLVVSVLISGNL VATL_SCHPO 55 1 -
IIPVVMAGVLGIYGLIIAVIIGNGV VATL_PLECA 54 1 -
VIPVIMAGIIGIYGLVVAMVLRGKV VATL_ASCSU 59 1 -
VIPVIMAGIIGIYGLVVAMVLKGKV VAL2_CAEEL 59 1 -
VVPVVMAGIIAIYGLVVSVLVSDSL VATL_CANTR 54 1 -
IVPVIMAGIIAIYGLVVSVLVCYSL VATL_YEAST 54 1 -
IIPVVMAGIVAIYGLVVAVIVSGKV VAL1_CAEEL 67 1 -
FIPVIFAGVIAIYGLIICVILVGGI VATL_DICDI 73 1 -
LIPVVMSGILAIYGLVVAVLIAGNL VM11_YEAST 60 1 -
VAPVVFAGIIGLYGLIVCILLFINV VATL_ENTHI 63 1 -
LFPVVFAGVIGLYGLIVCIVLFINV VATL_ENTDI 61 1 -
TLPVIMAGILSIYGLITSLLINSRV O62579 62 1 -

Motif 3 width=27
Element Seqn Id St Int Rpt
LAAGMAIGIVGDAGVRANAQQPKLFVG VATL_AVESA 107 26 -
LAAGMAIGIVGDAGVRANAQQPKLFVG VATL_ORYSA 107 26 -
LPAGMAIGIVGDAGVRANAQQPKLFVG O22054 113 24 -
LPAGMAIGIVGDAGVRANAQQPKLFVG O22053 112 24 -
LPAGMAIGIVGDAGVRANAQQPKLFVG O22052 113 24 -
LPAGMAIGIVGDAGVRANAQQPKLFVG O22038 121 24 -
LSAGMAIGIVGDAGVRANAQQPKLFVG VATL_ARATH 107 26 -
LSAGMAIGIVGDAGVRANAQQPKLFVG VATL_TOBAC 107 26 -
LSAGMAIGIVGDAGVRANAQQPKLFVG VATL_PHAAU 106 26 -
LSAGMAIGIVGDAGVRANAQQPKLFVG VATL_LYCES 106 26 -
LSAGMAIGIVGDAGVRANAQQPKLFVG VATL_KALDA 107 26 -
LSAGMAIGIVGDAGVRANAQQPKLFVG VATL_GOSHI 107 26 -
LSAGMAIGIVGDAGVRANAQQPKLFVG VATL_BETVU 107 26 -
LAAGFAIGIVGDAGVRGTAQQPRLFVG VATL_TORMA 103 23 -
LAAGFAIGIVGDAGVRGTAQQPRLFVG VATL_MOUSE 104 23 -
LAAGFAIGIVGDAGVRGTAQQPRLFVG VATL_MANSE 104 26 -
LAAGFAIGIVGDAGVRGTAQQPRLFVG VATL_HELVI 104 26 -
LAAGFAIGIVGDAGVRGTAQQPRLFVG VATL_AEDAE 106 25 -
LAAGFAIGIVGDAGVRGTAQQPRLFVG VATL_BOVIN 104 23 -
LAAGFAIGIVGDAGVRGTAQQPRLFVG VATL_SHEEP 104 23 -
LAAGFAIGIVGDAGVRGTAQQPRLFVG VATL_HUMAN 104 23 -
LAAGFAIGIVGDAGVRGTAQQPRLFVG VATL_DROME 108 25 -
MPAGMAIGIVGDAGVRANAQQPKLFVG O22037 107 24 -
LAAGFAIGIVGDAGVRGTAQQPRLYVG VATL_NEPNO 105 25 -
MPAGMAIGIVGDAGVRANAQQPKLFVG O22051 107 24 -
LAAGFAIGIVGDAGVRGTAQQPRLFVG VATL_NEUCR 103 24 -
LAAGFAIGIVGDAGVRGTAQQPRLFVA VATL_SCHPO 103 23 -
MAAGIAIGIVGDAGVRASAQQAKLYVG VATL_PLECA 108 29 -
LGAGYAIGIVGDAGVRGTAQQPRLFVG VATL_ASCSU 110 26 -
LGAGYAIGIVGDAGVRGTAQQPRLFVG VAL2_CAEEL 110 26 -
LAAGFAIGIVGDAGVRGTAQQPRLFVG VATL_CANTR 102 23 -
LAAGFAIGIVGDAGVRGSSQQPRLFVG VATL_YEAST 102 23 -
LGAGYAIGIAGDAGVRALSQQPRMFVG VAL1_CAEEL 118 26 -
LAAGMAIGIVGDSGVRAFGQQPKLYVI VATL_DICDI 123 25 -
LSSGYAIGMVGDVGVRKYMHQPRLFVG VM11_YEAST 110 25 -
LASGMAIGISGDCGVRGAAQQPKLFVG VATL_ENTHI 112 24 -
LASGMSIGISGDCGVRGAAQQPKLFVS VATL_ENTDI 110 24 -
LAAGLAIGVSGSAAVKAVAKQPSLFVV O62579 113 26 -

Motif 4 width=24
Element Seqn Id St Int Rpt
MILILIFAEALALYGLIVGIILSS VATL_AVESA 134 0 -
MILILIFAEALALYGLIVGIILSS VATL_ORYSA 134 0 -
MILILIFAEALALYGLIVGIILAS O22054 140 0 -
MILILIFAEALALYGLIVGIILAS O22053 139 0 -
MILILIFAEALALYGLIVGIILAS O22052 140 0 -
MILILIFAEALALYGLIVGIILAS O22038 148 0 -
MILILIFAEALALYGLIVGIILSS VATL_ARATH 134 0 -
MILILIFAEALALYGLIVGIILSS VATL_TOBAC 134 0 -
MILILIFAEALALYGLIVGIILSS VATL_PHAAU 133 0 -
MILILIFAEALALYGLIVGIILSS VATL_LYCES 133 0 -
MILILIFAEALALYGLIVGIILSS VATL_KALDA 134 0 -
MILILIFAEALALYGLIVGIILSS VATL_GOSHI 134 0 -
MILILIFAEALALYGLIVGIILSS VATL_BETVU 134 0 -
MILILIFAEVLGLYGLIVALILST VATL_TORMA 130 0 -
MILILIFAEVLGLYGLIVALILST VATL_MOUSE 131 0 -
MILILIFAEVLGLYGLIVAIYLYT VATL_MANSE 131 0 -
MILILIFAEVLGLYGLIVAIYLYT VATL_HELVI 131 0 -
MILILIFAEVLGLYGLIVAIYLYT VATL_AEDAE 133 0 -
MILILIFAEVLGLYGLIVALILST VATL_BOVIN 131 0 -
MILILIFAEVLGLYGLIVALILST VATL_SHEEP 131 0 -
MILILIFAEVLGLYGLIVALILST VATL_HUMAN 131 0 -
MILILIFAEVLGLYGLIVAIYLYT VATL_DROME 135 0 -
VILILIFAEALALYGLIVGIILAS O22037 134 0 -
MILILIFAEVLGLYGLIVAIFLYT VATL_NEPNO 132 0 -
VILILIFAEALALYGLIVGIILAS O22051 134 0 -
MILILIFAEVLGLYGLIVALLMNS VATL_NEUCR 130 0 -
MILILIFAEVLGLYGLIVALLLNT VATL_SCHPO 130 0 -
MVLILIFAEALGLYGLIVGLILTS VATL_PLECA 135 0 -
MILILIFSEVLGLYGMIVALILGT VATL_ASCSU 137 0 -
MILILIFSEVLGLYGMIVALILGT VAL2_CAEEL 137 0 -
MILILIFAEVLGLYGLIVALLLNS VATL_CANTR 129 0 -
MILILIFAEVLGLYGLIVALLLNS VATL_YEAST 129 0 -
MILILIFAEVLGLYGMIVALILGA VAL1_CAEEL 145 0 -
MMLILIFSEALGLYGLIIGILLSS VATL_DICDI 150 0 -
IVLILIFSEVLGLYGMIVALILNT VM11_YEAST 137 0 -
MLICLIFSEALALYGFIVALIMAS VATL_ENTHI 139 0 -
MLICLIFSEALALYGFIVALIMAA VATL_ENTDI 137 0 -
MLIVLIFSEALALYGLIIALILST O62579 140 0 -