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PR00802

Identifier
SERUMALBUMIN  [View Relations]  [View Alignment]  
Accession
PR00802
No. of Motifs
7
Creation Date
13-FEB-1998  (UPDATE 28-JUN-1999)
Title
Serum albumin family signature
Database References
PRINTS; PR00803 AFETOPROTEIN; PR00804 VITAMNDBNDNG
PROSITE; PS00212 ALBUMIN
BLOCKS; BL00212
PFAM; PF00273 transport_prot
INTERPRO; IPR000264
Literature References
1. HAEFLIGER, D.N., MOSKAITIS, J.E., SCHOENBERG, D.R. AND WAHLI, W.
Amphibian albumins as members of the albumin, alpha-fetoprotein, 
vitamin-D-binding protein multigene family.
J.MOL.EVOL. 29 344-354 (1989).
 
2. SCHOENTGEN, F., METZ-BOUTIGUE, M.-H., JOLLES, J., CONSTANS, J.
AND JOLLES, P.
Complete amino-acid sequence of human vitamin-D-binding protein (group-
specific component) - evidence of a 3-fold internal homology as in serum-
albumin and alpha-fetoprotein.
BIOCHIM.BIOPHYS.ACTA 871 189-198 (1986).
 
3. LICHENSTEIN, H.S., LYONS, D.E., WURFEL, M.M., JOHNSON, D.A.,
MCGINLEY, M.D., LEIDLI, J.C., TROLLINGER, D.B., MAYER, J.P., WRIGHT, S.D.
AND ZUKOWSKI, M.M.
Afamin is a new member of the albumin, alpha-fetoprotein, and 
vitamin-D-binding protein gene family.
J.BIOL.CHEM. 269 18149-18154 (1994).
 
4. HE, X.M. AND CARTER, D.C.
Atomic structure and chemistry of human serum albumin.
NATURE 358 209-215 (1992). 

Documentation
A number of serum transport proteins are known to be evolutionarily related,
including albumin, alpha-fetoprotein, vitamin D-binding protein and afamin
[1-3]. Albumin is the main protein of plasma; it binds water, cations (such
as Ca++, Na+ and  K+), fatty acids, hormones, bilirubin and drugs - its main
function is to regulate the colloidal osmotic pressure of blood. Alphafeto-
protein (alpha-fetoglobulin) is a foetal plasma protein that binds various
cations, fatty acids and bilirubin. Vitamin D-binding protein binds to
vitamin D and its metabolites, as well as to fatty acids. The biological
role of afamin (alpha-albumin) has not yet been characterised.
 
The 3D structure of human serum albumin has been determined by X-ray
crystallography to a resolution of 2.8A [4]. It comprises three homologous
domains that assemble to form a heart-shaped molecule [4]. Each domain is a
product of two subdomains that possess common structural motifs [4]. The
principal regions of ligand binding to human serum albumin are located in 
hydrophobic cavities in subdomains IIA and IIIA, which exhibit similar
chemistry. Structurally, the serum albumins are similar, each domain
containing five or six internal disulphide bonds, as shown schematically
below: 
 
                   +---+          +----+                        +-----+
                   |   |          |    |                        |     |
xxCxxxxxxxxxxxxxxxxCCxxCxxxxCxxxxxCCxxxCxxxxxxxxxCxxxxxxxxxxxxxxCCxxxxCxxxx
  |                 |       |     |              |               |
  +-----------------+       +-----+              +---------------+
 
 
SERUMALBUMIN is a 7-element fingerprint that provides a signature for the
serum albumin family. The fingerprint was derived from an initial alignment
of 15 sequences: the motifs were drawn from short conserved regions spanning 
the central portion of the alignment - motifs 1-3 lie in the first domain;
motifs 4-6 lie in the second domain; and motif 7 lies in the third domain.
Two iterations on OWL29.6 were required to reach convergence, at which point
a true set comprising 35 sequences was identified. Several partial matches
were also found, all of which are either fragments or serum albumin proteins
that fail to match one or more motifs.
 
An update on SPTR37_9f identified a true set of 27 sequences, and 1
partial match.
Summary Information
  27 codes involving  7 elements
1 codes involving 6 elements
0 codes involving 5 elements
0 codes involving 4 elements
0 codes involving 3 elements
0 codes involving 2 elements
Composite Feature Index
727272727272727
61111011
50000000
40000000
30000000
20000000
1234567
True Positives
AFAM_HUMAN    AFAM_RAT      ALB1_SALSA    ALB2_SALSA    
ALB2_XENLA ALBU_BOVIN ALBU_CHICK ALBU_FELCA
ALBU_HORSE ALBU_HUMAN ALBU_MERUN ALBU_PETMA
ALBU_RABIT ALBU_RAT ALBU_SHEEP FETA_GORGO
FETA_HORSE FETA_HUMAN FETA_MOUSE FETA_RAT
O77705 O89020 Q28789 Q91134
VTDB_HUMAN VTDB_RABIT VTDB_RAT
True Positive Partials
Codes involving 6 elements
ALB1_XENLA
Sequence Titles
AFAM_HUMAN  AFAMIN PRECURSOR (ALPHA-ALBUMIN) (ALPHA-ALB) - HOMO SAPIENS (HUMAN). 
AFAM_RAT AFAMIN PRECURSOR (ALPHA-ALBUMIN) (ALPHA-ALB) - RATTUS NORVEGICUS (RAT).
ALB1_SALSA SERUM ALBUMIN 1 PRECURSOR - SALMO SALAR (ATLANTIC SALMON).
ALB2_SALSA SERUM ALBUMIN 2 PRECURSOR - SALMO SALAR (ATLANTIC SALMON).
ALB2_XENLA 74 KD SERUM ALBUMIN PRECURSOR - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
ALBU_BOVIN SERUM ALBUMIN PRECURSOR - BOS TAURUS (BOVINE).
ALBU_CHICK SERUM ALBUMIN PRECURSOR - GALLUS GALLUS (CHICKEN).
ALBU_FELCA SERUM ALBUMIN PRECURSOR - FELIS SILVESTRIS CATUS (CAT).
ALBU_HORSE SERUM ALBUMIN PRECURSOR - EQUUS CABALLUS (HORSE).
ALBU_HUMAN SERUM ALBUMIN PRECURSOR - HOMO SAPIENS (HUMAN).
ALBU_MERUN SERUM ALBUMIN PRECURSOR - MERIONES UNGUICULATUS (MONGOLIAN JIRD).
ALBU_PETMA SERUM ALBUMIN PRECURSOR - PETROMYZON MARINUS (SEA LAMPREY).
ALBU_RABIT SERUM ALBUMIN PRECURSOR - ORYCTOLAGUS CUNICULUS (RABBIT).
ALBU_RAT SERUM ALBUMIN PRECURSOR - RATTUS NORVEGICUS (RAT).
ALBU_SHEEP SERUM ALBUMIN PRECURSOR - OVIS ARIES (SHEEP).
FETA_GORGO Alpha-fetoprotein precursor (Alpha-fetoglobulin) (Alpha-1- fetoprotein) - Gorilla gorilla gorilla (Lowland gorilla).
FETA_HORSE Alpha-fetoprotein precursor (Alpha-fetoglobulin) (Alpha-1- fetoprotein) - Equus caballus (Horse).
FETA_HUMAN Alpha-fetoprotein precursor (Alpha-fetoglobulin) (Alpha-1- fetoprotein) - Homo sapiens (Human).
FETA_MOUSE Alpha-fetoprotein precursor (Alpha-fetoglobulin) (Alpha-1- fetoprotein) - Mus musculus (Mouse).
FETA_RAT Alpha-fetoprotein precursor (Alpha-fetoglobulin) (Alpha-1- fetoprotein) - Rattus norvegicus (Rat).
O77705 ALBUMIN - CANIS FAMILIARIS (DOG).
O89020 AFAMIN PRECURSOR (ALPHA-ALBUMIN) (ALPHA-ALB) - MUS MUSCULUS (MOUSE).
Q28789 ALPHA-FETOPROTEIN PRECURSOR - PAN TROGLODYTES (CHIMPANZEE).
Q91134 COBRA SERUM ALBUMIN - NAJA NAJA (INDIAN COBRA).
VTDB_HUMAN VITAMIN D-BINDING PROTEIN PRECURSOR (DBP) (GROUP-SPECIFIC COMPONENT) (GC-GLOBULIN) (VDB) - HOMO SAPIENS (HUMAN).
VTDB_RABIT VITAMIN D-BINDING PROTEIN PRECURSOR (DBP) (GROUP-SPECIFIC COMPONENT) (GC-GLOBULIN) (VDB) - ORYCTOLAGUS CUNICULUS (RABBIT).
VTDB_RAT VITAMIN D-BINDING PROTEIN PRECURSOR (DBP) (GROUP-SPECIFIC COMPONENT) (GC-GLOBULIN) (VDB) - RATTUS NORVEGICUS (RAT).

ALB1_XENLA 68 KD SERUM ALBUMIN PRECURSOR - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
Scan History
OWL29_6    2  100  NSINGLE    
SPTR37_9f 4 100 NSINGLE
Initial Motifs
Motif 1  width=15
Element Seqn Id St Int Rpt
GCCNQSGVERHQCLL FETA_RAT 114 114 -
MCCEKTAAERTHCFV ALB2_SALSA 106 106 -
ECCTKEGLGRKLCMA VTDB_RABIT 110 110 -
ECCTKEGLERKLCMA VTDB_HUMAN 110 110 -
DCCEKEEPERNECFL ALBU_PIG 111 111 -
ECCTKEGLERKLCMA VTDB_MOUSE 106 106 -
DCCTKQEPERNECFL P07724 35 35 -
DCCEKKEPERNECFL ALBU_FELCA 113 113 -
DCCEKQEPERNECFL ALBU_HORSE 113 113 -
DCCSQSEEGRHNCFL FETA_HUMAN 112 112 -
DCCSQSEEGRHNCFL FETA_GORGO 112 112 -
GCCSQNEEERHNCLL FETA_HORSE 112 112 -
GCCSQSGVERHQCLL FETA_MOUSE 108 108 -
HCCSKVDAQRRLCFF AFAM_HUMAN 112 112 -

Motif 2 width=24
Element Seqn Id St Int Rpt
CQAYESNRESLLNHFLYEVARRNP AFAM_HUMAN 148 21 -
CKAHEENRAVFMNRFIYEVSRRNP FETA_MOUSE 144 21 -
CKAYEENREMFLNRYLYEIARRHP FETA_HORSE 148 21 -
CEAYEEDRETFMNKFIYEIARRHP FETA_GORGO 148 21 -
CADFQEDEQKFWGKYLYEIARRHP ALBU_PIG 145 19 -
CEAFRRDPKGFADQFLYEYSSNYG VTDB_MOUSE 141 20 -
CEAYEEDRETFMNKFIYEIARRHP FETA_HUMAN 148 21 -
CAAFQEDPDKFLGKYLYEVARRHP ALBU_HORSE 147 19 -
CTSFKENPTTFMGHYLHEVARRHP P07724 70 20 -
CTAFHENEQRFLGKYLYEIARRHP ALBU_FELCA 148 20 -
CEAFRKDPKEYANQFMWEYSTNYG VTDB_HUMAN 145 20 -
CEAFRQDPMEFADKFLYEYSSNYG VTDB_RABIT 145 20 -
CEDFKKDHKAFVGRFIFKFSKSNP ALB2_SALSA 142 21 -
CPAYEENRAMSINTFIYDVSKRNP FETA_RAT 150 21 -

Motif 3 width=18
Element Seqn Id St Int Rpt
FEEVAKSCCEEQNKVNCL AFAM_HUMAN 185 13 -
YNEILTQCCAEADKESCL P07724 107 13 -
YKDVFSECCQAADKAACL ALBU_PIG 182 13 -
YLSMVGSCCTSANPTVCF VTDB_MOUSE 178 13 -
YKGVFTECCEAADKAACL ALBU_FELCA 185 13 -
YKADFTECCPADDKLACL ALBU_HORSE 184 13 -
YDKIIPSCCKAENAVECF FETA_HUMAN 185 13 -
YDKIIPSCCKAENAVECF FETA_GORGO 185 13 -
YDKIISACCKSENAVECF FETA_HORSE 185 13 -
YDKVVLACCKADNKEECF FETA_MOUSE 181 13 -
YDKAVPACCKADNMEECF FETA_RAT 187 13 -
YGEVLTTCCGEAEAQTCF ALB2_SALSA 179 13 -
YLSMVGTCCTSASPTVCF VTDB_RABIT 182 13 -
YLSMVGSCCTSASPTVCF VTDB_HUMAN 182 13 -

Motif 4 width=24
Element Seqn Id St Int Rpt
EIQKLVLDVAHVHEHCCRGDVLDC FETA_HUMAN 254 51 -
NVLPLAEDFTEILSRCCESTSEDC VTDB_MOUSE 246 50 -
EISKIVTDLAKVHKECCHGDLLEC ALBU_PIG 251 51 -
DVLPLAEDITNILSKCCESASEDC VTDB_HUMAN 250 50 -
EVLPLAEDITNILSKCCESTSEDC VTDB_RABIT 250 50 -
EMAGMVDKIVATVAPCCSGDMVTC ALB2_SALSA 248 51 -
EIRKLALDVAHIHEQCCHGNAMEC FETA_RAT 256 51 -
EITKLATDLTKVNKECCHGDLLEC P07724 176 51 -
ELISLVEDVSSNYDGCCEGDVVQC AFAM_HUMAN 254 51 -
EIQKLALDVAHIHEECCQGNSLEC FETA_MOUSE 250 51 -
EIQKLVLDVAHAHEECCRGNVEEC FETA_HORSE 254 51 -
EIQKLVLDVAHVHEHCCRGDVLDC FETA_GORGO 254 51 -
EISKLVTDLAKIHKECCHGDLLEC ALBU_FELCA 254 51 -
EVSKIVTDLTKVHKECCHGDLLEC ALBU_HORSE 253 51 -

Motif 5 width=14
Element Seqn Id St Int Rpt
FMASFLHEYSRTHP FETA_MOUSE 346 72 -
FLGTFLYEYSRRHP ALBU_FELCA 350 72 -
FLGTFLYEYSRRHP ALBU_HORSE 349 72 -
FLASFVHEYSRRHP FETA_HUMAN 350 72 -
FLASFVHEYSRRHP FETA_GORGO 350 72 -
FMARFTYEYSRRHT FETA_HORSE 350 72 -
FFAKFTFEYSRRHP AFAM_HUMAN 350 72 -
FMASFLHEYSRNHP FETA_RAT 352 72 -
AMGKLVYEISVRHP ALB2_SALSA 346 74 -
VMDQYTFELSRKTH VTDB_RABIT 342 68 -
VMDKYTFELSRRTH VTDB_HUMAN 342 68 -
AMDQYTFELSRRTQ VTDB_MOUSE 338 68 -
FLGTFLYEYSRRHP ALBU_PIG 347 72 -
FLGTFLYEYSRRHP P07724 272 72 -

Motif 6 width=24
Element Seqn Id St Int Rpt
ILRFAKEAEQALLQCCDMEDHAEC ALB2_SALSA 366 6 -
LLRIAKIYEATLEDCCAKEDPPAC ALBU_PIG 367 6 -
LLRLAKKYEATLEKCCAEANPPAC P07724 292 6 -
LSKVLEPTLKTLRECCDTQDSVAC VTDB_MOUSE 357 5 -
LLRLAKEYEATLEKCCATDDPPAC ALBU_FELCA 370 6 -
LLRIAKTYEATLEKCCAEADPPAC ALBU_HORSE 369 6 -
ILRVAKGYQELLEKCFQTENPLEC FETA_HUMAN 370 6 -
ILRVAKGYQELLEKCFQTENPLEC FETA_GORGO 370 6 -
ILRVAKGYQEFLEKCSQSENPLEC FETA_HORSE 370 6 -
LSKVLEPTLKSLSECCHSADSTAC VTDB_RABIT 361 5 -
LSKVLEPTLKSLGECCDVEDSTTC VTDB_HUMAN 361 5 -
ILRIAKTYQEILEKCSQSGNLPGC FETA_MOUSE 366 6 -
LLRIVQIYKDLLRNCCNTENPPGC AFAM_HUMAN 370 6 -
ILKTAKSYQEILEKCSQSETPSKC FETA_RAT 372 6 -

Motif 7 width=23
Element Seqn Id St Int Rpt
PQVSTPTLVEVARKLGLVGSRCC ALBU_PIG 437 46 -
PQVSTPTLVEAARNLGRVGTKCC P07724 362 46 -
PQVSTPTLVEIGRTLGKVGSRCC ALBU_HORSE 439 46 -
PDATPKELAKLVNKRSDFASNCC VTDB_HUMAN 431 46 -
PEATSAELAELVEKHSDFASKCC VTDB_RABIT 431 46 -
PQASFDQLHMVSETVHDVLHACC ALB2_SALSA 438 48 -
PQLTSAELIDLTGKMVSIASTCC FETA_RAT 442 46 -
PQLSTEELVSLGEKMVTAFTTCC AFAM_HUMAN 440 46 -
PQLTSAELIDLTGKMVSIASTCC FETA_MOUSE 436 46 -
PQLTPPELIALTRKMATAAATCC FETA_HORSE 440 46 -
PQLTSSELMAITRKMAATAATCC FETA_GORGO 440 46 -
PQVSTPTLVEVSRSLGKVGSKCC ALBU_FELCA 440 46 -
PNTSPAELKDMVEKHSDFASKCC VTDB_MOUSE 427 46 -
PQLTSSELMAITRKMAATAATCC FETA_HUMAN 440 46 -
Final Motifs
Motif 1  width=15
Element Seqn Id St Int Rpt
DCCEKKEPERNECFL ALBU_FELCA 113 113 -
DCCEKQEPDRNECFL O77705 90 90 -
DCCEKQEPERNECFL ALBU_HORSE 113 113 -
DCCEKQEPERNECFL ALBU_BOVIN 113 113 -
DCCEKQEPERNECFL ALBU_SHEEP 113 113 -
DCCEKKEPERNECFL ALBU_RABIT 113 113 -
DCCAKQEPERNECFL ALBU_HUMAN 113 113 -
DCCAKQEPERNECFL ALBU_MERUN 114 114 -
DCCAKQEPERNECFL ALBU_RAT 113 113 -
DCCSQSEEGRHNCFL Q28789 112 112 -
DCCSQSEEGRHNCFL FETA_HUMAN 112 112 -
DCCSQSEEGRHNCFL FETA_GORGO 112 112 -
GCCSQNEEERHNCLL FETA_HORSE 112 112 -
DCCSKADPERNECFL ALBU_CHICK 116 116 -
GCCSQSGVERHQCLL FETA_MOUSE 108 108 -
HCCSKVDAQRRLCFF AFAM_HUMAN 112 112 -
GCCNQSGVERHQCLL FETA_RAT 114 114 -
HCCGKAGFPRRLCFF O89020 112 112 -
HCCRQAGFQRRLCFF AFAM_RAT 112 112 -
DCCAKADPDRNECVL Q91134 116 116 -
ECCAKQDPERAQCFK ALB2_XENLA 115 115 -
MCCEKTAAERTHCFV ALB1_SALSA 106 106 -
MCCEKTAAERTHCFV ALB2_SALSA 106 106 -
ECCTKEGLERKLCMA VTDB_RAT 110 110 -
ECCTKEGLGRKLCMA VTDB_RABIT 110 110 -
ECCTKEGLERKLCMA VTDB_HUMAN 110 110 -
RCCALAGSERHDCFH ALBU_PETMA 123 123 -

Motif 2 width=24
Element Seqn Id St Int Rpt
CTAFHENEQRFLGKYLYEIARRHP ALBU_FELCA 148 20 -
CAAFQDNEQLFLGKYLYEIARRHP O77705 125 20 -
CAAFQEDPDKFLGKYLYEVARRHP ALBU_HORSE 147 19 -
CDEFKADEKKFWGKYLYEIARRHP ALBU_BOVIN 147 19 -
CAEFKADEKKFWGKYLYEVARRHP ALBU_SHEEP 147 19 -
CKAFHDDEKAFFGHYLYEVARRHP ALBU_RABIT 148 20 -
CTAFHDNEETFLKKYLYEIARRHP ALBU_HUMAN 148 20 -
CTAFQENAEAFMGHYLHEVARRHP ALBU_MERUN 149 20 -
CTSFQENPTSFLGHYLHEVARRHP ALBU_RAT 148 20 -
CEAYEEDRETFMNKFIYEIARRHP Q28789 148 21 -
CEAYEEDRETFMNKFIYEIARRHP FETA_HUMAN 148 21 -
CEAYEEDRETFMNKFIYEIARRHP FETA_GORGO 148 21 -
CKAYEENREMFLNRYLYEIARRHP FETA_HORSE 148 21 -
CQEYQDNRVSFLGHFIYSVARRHP ALBU_CHICK 152 21 -
CKAHEENRAVFMNRFIYEVSRRNP FETA_MOUSE 144 21 -
CQAYESNRESLLNHFLYEVARRNP AFAM_HUMAN 148 21 -
CPAYEENRAMSINTFIYDVSKRNP FETA_RAT 150 21 -
CQAYKNKSESFLHLYMYEVARRNP O89020 148 21 -
CQAYKNNSESFLNLYMYEVARRNP AFAM_RAT 148 21 -
CQAFQNDRDSVLAQYIFELSRRYP Q91134 152 21 -
CKLLKEHPDDLLSAFIHEEARNHP ALB2_XENLA 147 17 -
CEDFKKDHKAFVGRFIFKFSKSNP ALB1_SALSA 142 21 -
CEDFKKDHKAFVGRFIFKFSKSNP ALB2_SALSA 142 21 -
CEAFRKDPKGFADQFLFEYSSNYG VTDB_RAT 145 20 -
CEAFRQDPMEFADKFLYEYSSNYG VTDB_RABIT 145 20 -
CEAFRKDPKEYANQFMWEYSTNYG VTDB_HUMAN 145 20 -
CALHATANARLYDTLLWEFSRRYP ALBU_PETMA 167 29 -

Motif 3 width=18
Element Seqn Id St Int Rpt
YKGVFTECCEAADKAACL ALBU_FELCA 185 13 -
YKGVFAECCQAADKAACL O77705 162 13 -
YKADFTECCPADDKLACL ALBU_HORSE 184 13 -
YNGVFQECCQAEDKGACL ALBU_BOVIN 184 13 -
YNGVFQECCQAEDKGACL ALBU_SHEEP 184 13 -
YKAILTECCEAADKGACL ALBU_RABIT 185 13 -
YKAAFTECCQAADKAACL ALBU_HUMAN 185 13 -
YTAVLTECCAADDKGACL ALBU_MERUN 186 13 -
YNEVLTQCCTESDKAACL ALBU_RAT 185 13 -
YDKIIPSCCKAENAVECF Q28789 185 13 -
YDKIIPSCCKAENAVECF FETA_HUMAN 185 13 -
YDKIIPSCCKAENAVECF FETA_GORGO 185 13 -
YDKIISACCKSENAVECF FETA_HORSE 185 13 -
FEHALQSCCKESDVGACL ALBU_CHICK 189 13 -
YDKVVLACCKADNKEECF FETA_MOUSE 181 13 -
FEEVAKSCCEEQNKVNCL AFAM_HUMAN 185 13 -
YDKAVPACCKADNMEECF FETA_RAT 187 13 -
FEEAATTCCEQQQKATCF O89020 185 13 -
FEEAATTCCEQQQKATYF AFAM_RAT 185 13 -
YKKILETCCAEADKDACI Q91134 189 13 -
YHKLAEHCCEEEDKEKCF ALB2_XENLA 184 13 -
YGEVLTTCCGEAEAQTCF ALB1_SALSA 179 13 -
YGEVLTTCCGEAEAQTCF ALB2_SALSA 179 13 -
YLSMVGSCCTSAKPTVCF VTDB_RAT 182 13 -
YLSMVGTCCTSASPTVCF VTDB_RABIT 182 13 -
YLSMVGSCCTSASPTVCF VTDB_HUMAN 182 13 -
ITGLTTCCLVEEEHGACL ALBU_PETMA 205 14 -

Motif 4 width=24
Element Seqn Id St Int Rpt
EISKLVTDLAKIHKECCHGDLLEC ALBU_FELCA 254 51 -
EISKVVTDLTKVHKECCHGDLLEC O77705 231 51 -
EVSKIVTDLTKVHKECCHGDLLEC ALBU_HORSE 253 51 -
EVTKLVTDLTKVHKECCHGDLLEC ALBU_BOVIN 253 51 -
DVTKIVTDLTKVHKECCHGDLLEC ALBU_SHEEP 253 51 -
DISKIVTDLTKVHKECCHGDLLEC ALBU_RABIT 254 51 -
EVSKLVTDLTKVHTECCHGDLLEC ALBU_HUMAN 254 51 -
EITKLATDLTKVTQECCHGDLLEC ALBU_MERUN 255 51 -
EITKLATDVTKINKECCHGDLLEC ALBU_RAT 254 51 -
EIQKLVLDVAHVHEHCCRGDVLDC Q28789 254 51 -
EIQKLVLDVAHVHEHCCRGDVLDC FETA_HUMAN 254 51 -
EIQKLVLDVAHVHEHCCRGDVLDC FETA_GORGO 254 51 -
EIQKLVLDVAHAHEECCRGNVEEC FETA_HORSE 254 51 -
EVSKFVHDSIGVHKECCEGDMVEC ALBU_CHICK 258 51 -
EIQKLALDVAHIHEECCQGNSLEC FETA_MOUSE 250 51 -
ELISLVEDVSSNYDGCCEGDVVQC AFAM_HUMAN 254 51 -
EIRKLALDVAHIHEQCCHGNAMEC FETA_RAT 256 51 -
DLTTLLEDVSSMYEGCCEGDVVHC O89020 254 51 -
DLTSLLEDVSSMYDGCCEGDVVQC AFAM_RAT 254 51 -
TITGIAEFVVHIYEEICMGDSVDV Q91134 258 51 -
LAHNFTEEVTHFIKDCCHDDMFEC ALB2_XENLA 253 51 -
EMGGMVDKIVATVAPCCSGDMVTC ALB1_SALSA 248 51 -
EMAGMVDKIVATVAPCCSGDMVTC ALB2_SALSA 248 51 -
DVLPLAEDLTEILSRCCKSTSEDC VTDB_RAT 250 50 -
EVLPLAEDITNILSKCCESTSEDC VTDB_RABIT 250 50 -
DVLPLAEDITNILSKCCESASEDC VTDB_HUMAN 250 50 -
LIQKLAHRFEVLAEKCCELGHSDR ALBU_PETMA 274 51 -

Motif 5 width=14
Element Seqn Id St Int Rpt
FLGTFLYEYSRRHP ALBU_FELCA 350 72 -
FLGTFLYEYSRRHP O77705 327 72 -
FLGTFLYEYSRRHP ALBU_HORSE 349 72 -
FLGSFLYEYSRRHP ALBU_BOVIN 349 72 -
FLGSFLYEYSRRHP ALBU_SHEEP 349 72 -
FLGKFLYEYSRRHP ALBU_RABIT 350 72 -
FLGMFLYEYARRHP ALBU_HUMAN 350 72 -
FLGTFLYEYSRRHP ALBU_MERUN 351 72 -
FLGTFLYEYSRRHP ALBU_RAT 350 72 -
FLASFVHEYSRRHP Q28789 350 72 -
FLASFVHEYSRRHP FETA_HUMAN 350 72 -
FLASFVHEYSRRHP FETA_GORGO 350 72 -
FMARFTYEYSRRHT FETA_HORSE 350 72 -
FMAEFVYEYSRRHP ALBU_CHICK 354 72 -
FMASFLHEYSRTHP FETA_MOUSE 346 72 -
FFAKFTFEYSRRHP AFAM_HUMAN 350 72 -
FMASFLHEYSRNHP FETA_RAT 352 72 -
FFAEFIYEYSRRHP O89020 350 72 -
FFAEFLYDYSRRHT AFAM_RAT 350 72 -
YKESFLFTLTRNHP Q91134 354 72 -
FLGRYLHAVSRKHQ ALB2_XENLA 349 72 -
AMGKLVYEISVRHP ALB1_SALSA 346 74 -
AMGKLVYEISVRHP ALB2_SALSA 346 74 -
AMDQYTFELSRRTQ VTDB_RAT 342 68 -
VMDQYTFELSRKTH VTDB_RABIT 342 68 -
VMDKYTFELSRRTH VTDB_HUMAN 342 68 -
LTDQVMFEFARRHP ALBU_PETMA 757 459 -

Motif 6 width=24
Element Seqn Id St Int Rpt
LLRLAKEYEATLEKCCATDDPPAC ALBU_FELCA 370 6 -
LLRLAKEYEATLEKCCATDDPPTC O77705 347 6 -
LLRIAKTYEATLEKCCAEADPPAC ALBU_HORSE 369 6 -
LLRLAKEYEATLEECCAKDDPHAC ALBU_BOVIN 369 6 -
LLRLAKEYEATLEDCCAKEDPHAC ALBU_SHEEP 369 6 -
LLRLGKAYEATLKKCCATDDPHAC ALBU_RABIT 370 6 -
LLRLAKTYETTLEKCCAAADPHEC ALBU_HUMAN 370 6 -
LLRLAKKYEATLEKCCAEADPHAC ALBU_MERUN 371 6 -
LLRLAKKYEATLEKCCAEGDPPAC ALBU_RAT 370 6 -
ILRVAKGYQELLEKCFQTENPLEC Q28789 370 6 -
ILRVAKGYQELLEKCFQTENPLEC FETA_HUMAN 370 6 -
ILRVAKGYQELLEKCFQTENPLEC FETA_GORGO 370 6 -
ILRVAKGYQEFLEKCSQSENPLEC FETA_HORSE 370 6 -
IMRIAKGYESLLEKCCKTDNPAEC ALBU_CHICK 374 6 -
ILRIAKTYQEILEKCSQSGNLPGC FETA_MOUSE 366 6 -
LLRIVQIYKDLLRNCCNTENPPGC AFAM_HUMAN 370 6 -
ILKTAKSYQEILEKCSQSETPSKC FETA_RAT 372 6 -
LLRITKVYMDFLEDCCSRENPAGC O89020 370 6 -
LLRITKVYKDLLEDCCNRKNPLSC AFAM_RAT 370 6 -
DLEILYKYEKLLEECCQSEHHVQC Q91134 374 6 -
LLQSAKEYESLLNKCCKTDNPPEC ALB2_XENLA 369 6 -
ILRFAKEAEQALLQCCDMEDHAEC ALB1_SALSA 366 6 -
ILRFAKEAEQALLQCCDMEDHAEC ALB2_SALSA 366 6 -
LSKVLDTTLKTLRECCDTQDSVSC VTDB_RAT 361 5 -
LSKVLEPTLKSLSECCHSADSTAC VTDB_RABIT 361 5 -
LSKVLEPTLKSLGECCDVEDSTTC VTDB_HUMAN 361 5 -
ILEIANRMSRGLARCCEQGNNVGC ALBU_PETMA 856 85 -

Motif 7 width=23
Element Seqn Id St Int Rpt
PQVSTPTLVEVSRSLGKVGSKCC ALBU_FELCA 440 46 -
PQVSTPTLVEVSRKLGKVGTKCC O77705 417 46 -
PQVSTPTLVEIGRTLGKVGSRCC ALBU_HORSE 439 46 -
PQVSTPTLVEVSRSLGKVGTRCC ALBU_BOVIN 439 46 -
PQVSTPTLVEISRSLGKVGTKCC ALBU_SHEEP 439 46 -
PQVSTPTLVEISRSLGKVGSKCC ALBU_RABIT 440 46 -
PQVSTPTLVEVSRNLGKVGSKCC ALBU_HUMAN 440 46 -
PQVSTPTLVEAARSLGRVGTHCC ALBU_MERUN 441 46 -
PQVSTPTLVEAARNLGRVGTKCC ALBU_RAT 440 46 -
PQLTSSELMAITRKMAATAATCC Q28789 440 46 -
PQLTSSELMAITRKMAATAATCC FETA_HUMAN 440 46 -
PQLTSSELMAITRKMAATAATCC FETA_GORGO 440 46 -
PQLTPPELIALTRKMATAAATCC FETA_HORSE 440 46 -
PQVPTDLLLETGKKMTTIGTKCC ALBU_CHICK 444 46 -
PQLTSAELIDLTGKMVSIASTCC FETA_MOUSE 436 46 -
PQLSTEELVSLGEKMVTAFTTCC AFAM_HUMAN 440 46 -
PQLTSAELIDLTGKMVSIASTCC FETA_RAT 442 46 -
PQLPMEELVSLSKEMVAALTTCC O89020 440 46 -
PQLPMEELVSLSKEMVAALATCC AFAM_RAT 440 46 -
PQAPTSFLIELTEKVGKVAEKCC Q91134 444 46 -
PQVSDETLIGIAHQMADIGEHCC ALB2_XENLA 439 46 -
PQASFDQLHMVSETVHDVLHACC ALB1_SALSA 438 48 -
PQASFDQLHMVSETVHDVLHACC ALB2_SALSA 438 48 -
PNASPEELADMVAKHSDFASKCC VTDB_RAT 431 46 -
PEATSAELAELVEKHSDFASKCC VTDB_RABIT 431 46 -
PDATPKELAKLVNKRSDFASNCC VTDB_HUMAN 431 46 -
PNASFEKVSQLARHFLSLAKKCC ALBU_PETMA 1069 189 -