1
INTEGRINA:
Seed alignment containing 12 sequences:

                       1         11        21        31        41        51        61        71        81        91        101       111       121       131       141       151       161       171       181       191       201       211       221       231       241       251       261       271       281       291       301       311       321       331       341       351       361       371       381       391       401       411       421       431       441       451       461       471       481       491       501       511       521       531       541       551       561       571       581       591       601       611       621       631       641       651       661       671       681       691       701       711       721       731       741       751       761       771       781       791       801       811       821       831       841       851       861       871       881       891       901       911       921       931       941       951       961       971       981       991       1001      1011      1021      1031      1041      1051      1061      1071      1081      1091      1101      1111      1121      1131      1141      1151      1161      1171      1181      1191      1201      1211      1221      1231      1241      1251      1261      1271      1281      1291      1301      1311      1321      1331      1341      1351      1361      1371      1381      1391      1401      1411 
                       |---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|-
 ITAL_HUMAN            -----MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNG----VIVGAPGE--G-NSTGSLYQCQS--GTGHCLPVTLRGS-NYT-----------------SKYLGMTLATDPTDGSILACDPGL-SRTCDQNTYLS-----------GLCYLFRQNLQGPMLQGRPGFQECIKGN----------------VDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNT--SYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNT--FGAINYVATEVFREELGARPDATKVLIIITDG----EATDSGNID-AAKD-----IIRYIIGIG-----KHFQTKESQETLHKFASKPASEFVK---ILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGH--AVVGAVGAKDWAGGFLDLKADLQDDTF----IGNEPLTPEVRAGYLGYTVTWLPSRQK--TSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGG-------------------RVFIYQRRQLGFEEVSELQGDPGYP--LGRFGEAITALTDINGDGLVDVAVGAP--------LEEQGAVYIFNGRHG-GLSPQPSQRIEGT-QVLSGIQ-WFGRSIHGVKDLEGDGLADVAVGAES--QMIVLSSRPVVDMVTLMSFSPAEIPVHEVE-CSYSTSNKMKEGVNITICFQIKSLYPQF--QGRLVANLTYTLQLDGHRTRRRGLFPGG-RHELRRNIAVT---TSMSCTDFSFHFPV---CVQDLISPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHS-ETWEIPFEKN-CGEDKKCEANLRVSFSPAR----------------SRALRLTAFA-SLSVELSLSNLEED----------AYWVQLDLHFPPGLSFRKVEMLKPHSQ---IPVSCEELPEESRLLSR-ALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNS-ATTIIPILYPINI--LIQDQEDSTLYVSFTPKGP-------KIHQVKHMYQVR--IQPSIH------DHNIPTLEA----VVGVPQPPSEGPITHQWSVQM---EPPVPCHY---------EDLERLPDAA-------------------------EPCLP--GALFR--CPVVFR---QEILVQVIGTLELVGEIEASSM---FSLCSSLSISF-NSSKHFHLYGSNAS-LAQVVMKVDVVYEKQ----MLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDSEQLASGQEAGDPGCLKPLHEKDSESGGGKD  
ITA6_HUMAN ---------------------------------------------------------------------------------------------------------------------------MAAAGQLCLLYLSAGLLS-------RLGAAFNLDTR---------EDNVIRKYGD---------PGSLFG---------------------FSLAMHWQLQPE----------DKRLLLVGAPRGE-ALPLQRANRTGGLYSCDITAR-GPCTRIEFDNDADPTSES----------KEDQWMGVTVQS---QGPGGKVVTCAH------RYEKRQHVNTKQESRDIFGRCYVLSQN------------------LRIEDDMDGGDWS---FCDGRLRGHEKFGSCQ-QGVAATFTKDFH-------YIVFGAPGTYNWKG-IVRVEQKNNTFFDMNIFEDGPYEVGGET----EHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDG-WQDIVIGAPQYFDRDGEVG-----------------GAVYVYMNQQGRWN-NVKPIRLNGTK--DSMFGIAVKNIGDINQDGYPDIAVGAP--------YDDLGKVFIYHGSAN-GINTKPTQVLKG-------ISPYFGYSIAGNMDLDRNSYPDVAVGSLS-DSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSG----ICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDN---IRDKLRPIPITASVEIQEPSSRRRVN--SLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQK-DIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPE---KQLSCVANQ----NGSQ--ADCELGNPFKRN-SNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSG-VAKPSQVYFGGTVVGEQAMKS---EDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKE-INSLNLTESHN--SRKKREITEKQIDDNRK------------FSLFAERKYQTLNCSVN-VNCVNIRCPLRGLD--SKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSKTVAQYSG---VPWWIILVAILAGILMLALLVFILWKCGFFKRNKKDHYDATYHKAEIHAQ--------PSDKERLTSDA-
ITA5_HUMAN ------------------------------------------------------------------------------------------MGSRTPESPLH---AV-----------------QLRWGPRRRPPLVPLLLLLV-PPP-PRVGGFNLDAE-----------APAVLSGP---------PGSFFG---------------------FSVEFYRPGTDG------------VSVLVGAPKAN--TSQPGVLQGGAVYLCPWGASPTQCTPIEFDSKGSRLLESSLSSSEGEEPVEYKSLQWFGAT--VRAHGSSILACAP------LYSWRTEKE-PLSD--PVGTCYLSTDN--------------F--TRILEYAPCR--------SDFSWAAGQGYCQG---GFSAEFTKTG--------RVVLGGPGSYFWQG--QILSATQEQIAESYYPEYLINLVQGQ-----LQTRQASSIYDDSYLGYSVAVGEFSGDD-TEDFVAGVPKGNLT-YGYVTILNGS--DIRSLYNFSGEQMASYFGYAVAATDVNGDG-LDDLLVGAPLLMDRTPDGR-------------PQEVGRVYVYLQ-HPAGIEPTPTLTLTGHDE-FGRFGSSLTPLGDLDQDGYNDVAIGAPFG-----GETQQGVVFVFPGGPG-GLGSKPSQVLQPL-WAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPIVSASASLTIFPAMFNPEERS-CSLEGN--PVACINLSFCLNASGKHVAD--SIGFTVELQLDWQKQKG-GVRRALFLAS-RQATLTQTLLIQNGAREDCREMKIYLRNES-EFRDKLSPIHIALNFSLDPQAPVDS------HGLRPALHYQSKSRIEDKAQILLD-CGEDNICVPDLQLEVFGE-----------------QNHVYLGDKN-ALNLTFHAQNVGEGG---------AYEAELRVTAPPEAEYSGLVRHPGNFS----SLSCDYFA---VNQSR-LLVCDLGNPMKAG-ASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSDVVS-FRLSVEAQAQVTLNGVSKPEAVLFPVSDWHPRDQPQ-KEEDLGPAVHHVYELINQGPSSISQ--GVLELSCPQALEG-QQLLYVTR--VTG-LNCTTNHPI---NPKGLELD-------PEGSLHHQQKRE---APSR-------SSASS-G-PQILKCPE--AECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQREHQ--PFSLQCEAVYKA-LKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILFGLLLLGLLIYILYKLGFFKRSLPYGTAMEKAQLK--PPA-------TSDA--
ITA1_HUMAN ------------------------------FNVDVKNSMTFSGPVED-MFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPV--GRGESLPCVKLDLPVNTSIPN-------VTEVKENMTFGSTLVTNPNGGFLA-CGPLY-AYRCGHLHYTT-----------GICSDVSP--TFQVVNSIAPVQECS-TQ----------------LDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPK--QTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMT-ALGTDTARKEAFTEARGARRGVKKVMVIVTDG----ESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFN---VSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQDW--VMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATASSG--DVLYIAGQPRYNHTGQVIIYRMEDG--NIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPC-GARFGTAIAAVKDLNLDGFNDIVIGAP-L-----EDDHGGAVYIYHGSGK-TIRKEYAQRIPSG-GDGKTLK-FFGQSIHGEMDLNGDGLTDVTIGGLG--GAALFWSRDVAVVKVTMNFEPNKVNIQKKN-CHMEGK--ETVCINATVCFEVKLKSKED---TIYEADLQYRVTLDSLRQISRSFFSGT-QERKVQRNITVR---KSECTKHSFYMLD----KHDFQDSVRITLDFNLTDPEN-----------G-PVLDDSLPNSVHEYIPFAKD-CGNKEKCISDLSLHVATTE----------------KDLLIVRSQNDKFNVSLTVKNTKDS----------AYNTRTIVHYSPNLVFSGIEAIQ--------KDSCESNH---------NITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNV-VNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPE--LKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFE---DPFSINSGK-----KMTTSTDHLKRGT------------------------ILDCNT--CKFATITCNLTSS---DISQVNVSLILWKPTFIKSYFS--SLNLTIRGELRS-ENASLVLSSSNQKR---ELAIQISKDGLPG--RVPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKKKMEK
ITAE_HUMAN ------------MWLFHTLLCIASLALLAAFNVDVARPWLTPKGGAPFVLSSLLHQDPSTNQTWLLVTSPRT---KRTPGPLHRCSLVQDEILCHPVEHVPIQGEAPGSDRCPEPPRCFDMHSSAGPAPHSLSSELTGTCSLLGPDLRPQAQANFFDLENLLDPDARVDTGDCYSNKEGGGEDDVNTARQRRALEKEEEEDKEEEEDEEEEEAGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQDVMASLARVQNITQVGSVTKT--ASAMQHVLDSIFTSSHGSRRKASKVMVVLTDG---GIFEDPLNLTTVINSPKMQGVERFAIGVG-----EEFKSARTARELNLIASDPDETHAFK---VTNYMALDGLLSKLRYNIISMEGTVGD---ALHYQLAQIGFSAQILDERQ-VLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCS---LSYVAGAPQYKHHGAVFELQKEGR--EASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGR-----------------VYVYRLSEQDGSFSLARILSGHPGFT--NARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWD-GLSASPSQRIRAS-TVAPGLQ-YFGMSMAGGFDISGDGLADITVGTLG--QAVVFRSRPVVRLKVSMAFTPSALPIGFN--GVVNVR----------LCFEISSVTTASE-SGLREALLNFTLDVDVGKQRRRLQCSDV-RSCLGCLREWSS--GSQLCEDLLLMPTEGELCEEDCFSNASVKVSYQLQTPEGQTD-------HPQPILDRYTEPFAIFQLPYEKA-CKNKLFCVAELQLATTVS-----------------QQELVVGLTK-ELTLNINLTNSGED----------SYMTSMALNYPRNLQLKRMQKPPSP------NIQCDDPQ---PVASVLIMNCRIGHPVLKR-SSAHVSVVWQLEENAFPNRTADITVTVTNSNERRSLANETH-TLQFRHGFVAVLS---K-PSIMYVNTGQGLSHHK---------EFLFHVHGENLFGAEYQL------QICVPTKLR----GLQVAAVKKLTRTQASTVCTW---SQERACAY---------SSVQHVEEWH-----------------------------------SVS-CVIASD----KENVTVAAEISWDHSEELLKD--VTELQILGEISF-NKSLYEGLNAENHR----TKITVVFLKDEKYH--SLPIIIKGSVGGLLVLIVILVILFKCGFFKRKYQQLNLESIRKAQLKSEN-------LLEEEN-
ITA4_HUMAN ---------------------------------------------------------------------------------------------MFPTESAWLGKR------------------GANPGPEAAVRETVMLLLCLG---VPTGRPYNVDTE-----------SALLYQGP---------HNTLFG---------------------YSVVLHSHGANR------------W-LLVGAPTAN-WLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCG-------KTCLEERDNQWLGVTLSRQPGENGSIVTCG-------HRWKNIFYIKNENKLPTGGCYGVPP--------------------DLRTELSKR------IAPCYQDYVKKFGEN----------FAS--------C-QAGISSFYTKDL--IVMGAPGSSYWTGSLFVYNITTNKYK-----AFLDKQNQVKFGSYLGYSVGAGHFRSQH-TTEVVGGAPQHEQIGKAYIFSIDEK--ELNILHEMKGKKLGSYFGASVCAVDLNADG-FSDLLVGAPMQSTIREEG-------------------RVFVYINSGSGAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQE------DDLQGAIYIYNGRAD-GISSTFSQRIEGL-QISKSLS-MFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLSHPES-VNRTKFD-CVENGWP--SVCIDLTLCFSYKGKEVPG--YIVLFYNMSLDVNRKAE-SPPRFYFSSNGTSDVITGSIQVS-SREANCRTHQAFMRKD---VRDILTPIQIEAAYHLGPHVISKRS-TEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CSADLQVSAKIGFLKP-----------HENKTYLAVGSMKTLMLNVSLFNAGDD----------AYETTLHVKLPVGLYFIKILELEEK------QINCEVTD----NSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENEPE----TCMVEKMNLTFHVINTGNSMAPN--VSVEIMVPNSFSPQTDKLFNILDVQTTTGECHFENYQR-VCALEQQKS-------AMQTLKGIVRFLS------------------KTDKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETS--ALKFEIRATGFP-EPNPRVIELNKDENVAHVLLEGLHHQRPKR--YFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEENRRDSWSYIN--------SKSNDD
ITAX_HUMAN -----MTRTRAALLLFTALA------TSLGFNLDTEELTAFRVDSAG--FGDSVVQYANSW---VVVGAPQKITAANQTGGLYQCGY--STGACEPIGLQVPPEAV-----------------NMSLGLSLASTTSPSQLLACGPTV-HHECGRNMYLT-----------GLCFLLGP--TQLTQRLPVSRQECPRQE----------------QDIVFLIDGSGSISSRNFATMMNFVRAVISQFQRP--STQFSLMQFSNKFQTHFTFEEFRRTSNPLSLLASVHQLQGFTYT--ATAIQNVVHRLFHASYGARRDATKILIVITDGKKEGDSLDYKDVI-PMAD--AAGIIRYAIGVG-----LAFQNRNSWKELNDIASKPSQEHIFK---VEDFDALKDIQNQLKEKIFAIEGTETTSSSSFELEMAQEGFSAVFTPDG--PVLGAVGSFTWSGGAFLYPPNMSPTF-----INMSQENVDMRDSYLGYSTELALWKG---VQSLVLGAPRYQHTGKAVIFTQVSR--QWRMKAEVTGTQIGSYFGASLCSVDVDTDGSTDLVLIGAPHYYEQTRGG----------------QVSVCPLPRG-WRRWWCDAVLYGEQGHP--WGRFGAALTVLGDVNGDKLTDVVIGAP-G-----EEENRGAVYLFHGVLGPSISPSHSQRIAGS-QLSSRLQ-YFGQALSGGQDLTQDGLVDLAVGARG--QVLLLRTRPVLWVGVSMQFIPAEIPRSAFE-CREQVVS-EQTLVQSNICLYIDKRSKNLLGSRDLQSSVTLDLALDPGRLSPRATFQET-KNRSLSRVRVL--GLKAHCENFNLLLPS---CVEDSVTPITLRLNFTLVGKPLLAF------RNLRPMLAALAQRYFTASLPFEKN-CGADHICQDNLGISFSFPG----------------LKSLLVGSNL-ELNAEVMVWNDGED----------SYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAP-VGSQGTW-STSCRINHLIFRGGAQITFLATFDVSPKAVLGDRLLLTANVSSEN-NTPRTSKTT-FQLELPVKYAVYT--VVSSHEQFTKYLNFSESEEK------ESHVAMHRYQVNNLGQRDLP---VSINFWVPVELN--QEAVWMDV-EVSHPQNPSLRCSS---EKIAPPAS---------DFLAHIQKNP------------------------VLDCSI--AGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQK--KVSVVSVAEITF-DTSVYSQLPGQEAFMRAQTTTVLEKYKVHN----PTPLIVGSSIGGLLLLALITAVLYKVGFFKRQYKEMMEEANGQIA--PEN-------GTQTPSPPSEK
ITA2_HUMAN MGPERTGAAPLPLLLVLALSQG-ILNCCLAYNVGLPEAKIFSGPSSE-QFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKCPVDLSTATCEKLNLQTS-TSIPN---------VTEMKTNMSLGLILTRNMGTGGFLTCGPLW-AQQCGNQYYTT-----------GVCSDISP-DFQLSASFSPATQPCP-SL----------------IDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPT--KTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTN-TFGAIQYARKYAYSAASGGRRSATKVMVVVTDG----ESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFN---VSDEAALLEKAGTLGEQIFSIEGTVQGG-DNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFP--KQAFDQILQDRNHSSYLGYSVAAISTGES---THFVAGAPRANYTGQIVLYSVNENG-NITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEE-----------------GRVYLFTIKKGILGQHQFLEGPEGIE--NTRFGSAIAALSDINMDGFNDVIVGSP-L-----ENQNSGAVYIYNGHQG-TIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFG--QVVQLWSQSIADVAIEASFTPEKITLVNKN-AQIILK----------LCFSAKFRPTKQNNQVAIVYNITLDADGFSSRVTSRGLFKEN-NERCLQKNMVVN--QAQSCPEHIIYIQE----PSDVVNSLDLRVDISLENPGTS------------PALEAYSETAKVFSIPFHKD-CGEDGLCISDLVLDVRQIPAA-----------Q--EQPFIVSNQNKRLTFSVTLKNKRES----------AYNTGIVVDFSENLFFASFSLPVDGT-----EVTCQVAA------SQKSVACDVGYPALKREQQVTFTINFDFNLQN-LQNQASLSFQALSES-QEENKADNL-VNLKIPLLYDAEIHLTRSTNINFYEISSDGNVPSIVHSFEDVGPKFIFSLKVT-TGSVPVSM--ATVIIHIPQYTKEKNPLMYLTGVQTDKAGDISCNADI---NPLKIGQTS-----SSVSFKSENFRHT-----------------------KELNCRT--ASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQ--TVQLTAAAEINT-YNPEIYVIEDNTVT----IPLMIMKPDEKA--EVPTGVIIGSIIAGILLLLALVAILWKLGFFKRKYEKMTKNPDEIDET------------TELSS-
ITAM_HUMAN -----MALR---VLLLTALT------LCHGFNLDTENAMTFQENARG--FGQSVVQLQGSR---VVVGAPQEIVAANQRGSLYQCDY--STGSCEPIRLQVPVEAV-----------------NMSLGLSLAATTSPPQLLACGPTV-HQTCSENTYVK-----------GLCFLFGSNLRQQPQKFPEALRGCPQED----------------SDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKS--KTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHT--ATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPLGYEDVI-PEAD--REGVIRYVIGVG-----DAFRSEKSRQELNTIASKPPRDHVFQ---VNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNG--PLLSTVGSYDWAGGVFLYTSKEKSTF-----INMTRVDSDMNDAYLGYAAAIILRNR---VQSLVLGAPRYQHIGLVAMFRQNTG--MWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGG----------------QVSVCPLPRG-RARWQCDAVLYGEQGQP--WGRFGAALTVLGDVNGDKLTDVAIGAP-G-----EEDNRGAVYLFHGTSGSGISPSHSQRIAGS-KLSPRLQ-YFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKAIMEFNPREVARNVFE-CNDQVVK-GKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNET-KNSTRRQTQVL--GLTQTCETLKLQLPN---CIEDPVSPIVLRLNFSLVGTPLSAF------GNLRPVLAEDAQRLFTALFPFEKN-CGNDNICQDDLSITFSFMS----------------LDCLVVGGPR-EFNVTVTVRNDGED----------SYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN-NMPRTNKTE-FQLELPVKYAVYM--VVTSHGVSTKYLNFTASEN-------TSRVMQHQYQVSNLGQRSLP---ISLVFLVPVRLN--QTVIWDRP-QVTFSENLSSTCHT---KERLPSHS---------DFLAELRKAP------------------------VVNCSI--AVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHN--HLLIVSTAEILF-NDSVFTLLPGQGAFVRSQTETKVEPFEVPN----PLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMSEG-G--P--P---------GAE-PQ
ITAV_HUMAN -------------------------------------------------------------------------------------------MAFPPRR-------------------------RLRLGPRGLPLLLSGLLL---P----LCRAFNLDVD-----------SPAEYSGP---------EGSYFG---------------------FAVDFFVPSASSR-----------MFLLVGAPKAN--TTQPGIVEGGQVLKCDWSST-RRCQPIEFDATGNRDYAK-------DDPLEFKSHQWFGAS--VRSKQDKILACAP------LYHWRTEMK-QERE--PVGTCFLQDG------------------TKTVEYAPCR--------SQDIDADGQGFCQG---GFSIDFTKAD--------RVLLGGPGSFYWQG--QLISDQVAEIVSKYDPNVYSIKYNNQ-----LATRTAQAIFDDSYLGYSVAVGDFNGDG-IDDFVSGVPRAART-LGMVYIYDGK--NMSSLYNFTGEQMAAYFGFSVAATDINGDD-YADVFIGAPLFMDRGSDGK-------------LQEVGQVSVSLQ-RASG--DFQTTKLNGFEV-FARFGSAIAPLGDLDQDGFNDIAIAAPYG-----GEDKKGIVYIFNGRST-GLNAVPSQILEGQ-WAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKT-CSLPGTALKVSCFNVRFCLKADGKGVLPR-KLNFQVELLLDKLKQKG-AIRRALFLYS-RSPSHSKNMTISRGGLMQCEELIAYLRDES-EFRDKLTPITIFMEYRLDYRTAADT------TGLQPILNQFTPANISRQAHILLD-CGEDNVCKPKLEVSVDSD-----------------QKKIYIGDDN-PLTLIVKAQNQGEG----------AYEAELIVSIPLQADFIGVVRNNEALA----RLSCAFKT---ENQTR-QVVCDLGNPMKAG-TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVS-HKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPE-TEEDVGPVVQHIYELRNNGPSSFSK--AMLHLQWPYKYNN-NTLLYILHYDIDGPMNCTSDMEI---NPLRIKISS-LQTTEKNDTVAGQGERDHL-ITKR-------DLALSEGDIHTLGCGV--AQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNV-IEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQ--PHE-------NGEGNSET
ITA3_HUMAN ----------------------------------------------------------------------------------------------------------------------------MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNL-----------DTRFLVVK----EAG-NPGSLFG---------------------YSVALHRQTERQ------QR----YLLLAGAPRELA-VPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHI----------IEDMWLGVTVAS---QGPAGRVLVCAH-------RYTQVLWSGSEDQRRMVGKCYVRGN--------------------DLELDSSD--------D--WQTYHNEMCNS-----NTDYLETG--------MCQLGTSGGFTQNT--VYFGAPGAYNWKGNSYMIQRKEWDLS-----EYSYKDPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGG-DLRRRQVLEGSQVGAYFGSAIALADLNNDG-WQDLLVGAPYYFERKEEVG-----------------GAIYVFMNQAGTSFPAHPSLLLHGPS--GSAFGLSVASIGDINQDGFQDIAVGAP--------FEGLGKVYIYHSSSK-GLLRQPQQVIHGEKLGLPGLA-TFGYSLSGQMDVDENFYPDLLVGSLS-DHIVLLRARPVIN-IVHKTLVPRPAVLDPAL-CTATSC------VQVELCFAYNQSAGNP--NYRRNITLAYTLEADRDRRPPRLRFAGS-ESAVFHGFFSMP---EMRCQKLELLLMDN---LRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKE-CGPDNKCESNLQMRAAFVSEQ-----------QQKLSRLQYSRDVRKLLLSINVTNTRTSERS----GEDAHEALLTLVVPPALLLSSVRPPG----------ACQANE------T---IFCELGNPFKRN-QRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLWPMIL-TLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKT---VEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSD----PGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAP--VVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAE---IELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKRQKAEMKSQ-------PSETERLTDDY
ITAB_HUMAN ---------------------------------------------------------------------------------------------------------M-----------------ARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPV-----------QLTFYAGP---------NGSQFG---------------------FSLDFHKDSHGR------------VAIVVGAPR----TLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVG--S----QTLQTFKARQGLGAS--VVSWSDVIVACAP------WQHWNVLEKTEEAEKTPVGSCFLAQPE-------S---------GRRAEYSPCRGNTLSRIYVENDFSWDKRYCEA---GFSSVVTQAG--------ELVLGAPGGYYFLG--LLAQAPVADIFSSYRPGILLWHVSSQS----LSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWT-LGAVEILDS---YYQRLHRLRAEQMASYFGHSVAVTDVNGDG-RHDLLVGAPLYMESRADRK-------------LAEVGRVYLFLQPRGPHALGAPSLLLTGTQL-YGRFGSAIAPLGDLDRDGYNDIAVAAPYG-----GPSGRGQVLVFLGQSE-GLRSRPSQVLD----SPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDS-LNPAVKS-CVLPQTKTPVSCFNIQMCVGATGHNIPQ--KLSLNAELQLDRQKPRQ--GRRVLLLGS-QQAGTTLNLDLGGKHSPICHTTMAFLRDEA-DFRDKLSPIVLSLNVSLPPTEA----------GMAPAVVLHGDTHVQEQTRIVLD-CGEDDVCVPQLQLTASVT-----------------GSPLLVGADN-VLELQMDAANEGEG----------AYEAELAVHLPQGAHYMRALSNVEGFE----RLICNQKK---ENETR-VVLCELGNPMKKN-AQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVL-LDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNS---LDSWGPKVEHTYELHNNGPGTVNG--LHLSIHLPGQSQP-SDLLYILDIQPQGGLQCFPQPPV---NPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEP-------EQPSRLQDPVLVSCDS--APCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLD--QFVLQSHAWFNV-SSLPYAVPPLSLPRGEAQVWTQLLRALEER--AIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEE----------------GE