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The PRINTS Fingerprint Database


PRINTS RELEASE NOTES 1.0 Current contents Release 38.1 of PRINTS contains 1904 entries, encoding 11,451 individual motifs. Overall, the database is still relatively small, largely because the detailed annotation of fingerprints is so time-consuming. Nevertheless, the additional, unique information contained in PRINTS makes this database a useful adjunct to PROSITE, Pfam, Blocks, etc.. PRINTS is released in major and minor versions: minor releases reflect updates, bringing the contents in line with the current version of the source database(s) (formerly, PRINTS was derived from OWL, but since version 23.1, the database has changed to SWISS-PROT and TrEMBL sources); major releases denote the addition of new material to the resource. We endeavour to make major releases available quarterly. 1.1 Database growth The database has gathered momentum since October 1993, from which time it has shown a >10-fold increase in size. We used to maintain a steady growth by adding around 50 new entries with each release, but this has proved impossible in recent years. The database growth since its first release is summarised below: DATABASE DATE NO.OF DATABASE TOTAL NO. VERSION ENTRIES OF MOTIFS 1.0 18.10.1991 29 116 1.1 16.10.1992 28 110 2.0 13.03.1993 59 279 2.1 16.04.1993 59 279 3.0 22.07.1993 104 486 4.0 29.10.1993 150 702 5.0 20.04.1994 200 951 6.0 22.07.1994 250 1211 7.0 22.11.1994 300 1433 8.0 22.03.1995 350 1686 9.0 22.07.1995 400 1942 9.1 14.11.1995 400 1942 10.0 21.12.1995 450 2227 11.0 08.04.1996 500 2559 12.0 21.06.1996 550 2875 12.1 22.08.1996 550 2874 13.0 29.09.1996 600 3197 13.a 03.11.1996 614 3280 14.0 16.12.1996 650 3504 15.0 15.04.1997 700 3838 16.0 16.06.1997 750 4136 17.0 13.09.1997 800 4460 18.0 31.03.1998 865 4892 19.0 20.07.1998 925 5334 20.0 25.10.1998 990 5701 21.0 03.01.1999 1050 6142 22.0 23.03.1999 1100 6510 23.0 30.06.1999 1160 6938 23.1 15.08.1999 1159 6935 24.0 01.10.1999 1210 7241 25.0 07.01.2000 1260 7559 26.0 29.03.2000 1310 7897 27.0 31.05.2000 1360 8244 28.0 25.09.2000 1410 8550 29.0 01.01.2001 1460 8880 30.0 30.03.2001 1500 9136 31.0 30.06.2001 1550 9531 32.0 23.09.2001 1600 9800 33.0 01.01.2002 1650 10085 34.0 01.04.2002 1700 10342 35.0 14.07.2002 1750 10626 36.0 11.04.2003 1800 10931 37.0 06.06.2003 1850 11170 38.0 16.06.2005 1900 11435 38.1 25.05.2007 1904 11451 1.2 Future directions We have now integrated PRINTS, PROSITE, profiles and Pfam within the framework of a single protein family annotation resource; the annotation server is based at the EBI, while the pattern databases continue to be managed from their respective host institutions. This collaborative European initiative, known as InterPro, aims to reduce duplication of effort by streamlining the current annotation bottleneck. InterPro is accessible at http://www.ebi.ac.uk/interpro/ 1.3 Citing PRINTS The most recent NAR publication is: PRINTS and its automatic supplement, prePRINTS. Attwood, T.K., Bradley, P., Flower, D.R., Gaulton, A., Maudling, N., Mitchell, A., Moulton, G., Nordle, A., Paine, K., Taylor, P., Uddin, A. and Zygouri, C. Nucleic Acids Research, 31(1), 400-402 (2003). References to other PRINTS-related publications can be found at: http://attwoodlab.smith.man.ac.uk/dbbrowser/index/biblio.html